K. Yi

发表

Integrative genome-scale metabolic analysis of Vibrio vulnificus for drug targeting and discovery

S. Lee, H. Kim, T. Kim, 2011, Molecular systems biology.

Studies on Benzofuran-7-carboxamides as Poly(ADP-ribose) Polymerase-1 (PARP-1) Inhibitors

K. Yi, Sunkyung Lee, B. Lee, 2012 .

A comparative molecular field analysis and molecular modelling studies on pyridylimidazole type of angiotensin II antagonists.

K. Yi, S. Lee, S. Yoo, 1999, Bioorganic & medicinal chemistry.

2-Heteroaryl Benzimidazole Derivatives as Melanin Concentrating Hormone Receptor 1 (MCH-R1) Antagonists

K. Yi, B. Lee, Kwang-Seok Oh, 2013 .

Predicted Ligands for the Human Urotensin‐II G Protein‐Coupled Receptor with Some Experimental Validation

W. Goddard, K. Yi, B. Trzaskowski, 2014, ChemMedChem.

KR-31761, a novel K+(ATP)-channel opener, exerts cardioprotective effects by opening both mitochondrial K+(ATP) and Sarcolemmal K+(ATP) channels in rat models of ischemia/reperfusion-induced heart injury.

K. Yi, H. Won, H. Seo, 2009, Journal of pharmacological sciences.

Pharmacodynamic characteristics and cardioprotective effects of new NHE1 inhibitors.

Min Goo Lee, K. Yi, Yi-Sook Jung, 2007, European journal of pharmacology.

KR-31378 protects cardiac H9c2 cells from chemical hypoxia-induced cell death via inhibition of JNK/p38 MAPK activation.

K. Yi, Yong-Sam Jung, Eunhee Kim, 2004, The Japanese journal of physiology.

KR-31378, a novel benzopyran analog, attenuates hypoxia-induced cell death via mitochondrial KATP channel and protein kinase C-epsilon in heart-derived H9c2 cells.

K. Yi, Yi-Sook Jung, M. J. Kim, 2004, European journal of pharmacology.

Cardioselective anti-ischemic ATP-sensitive potassium channel (KATP) openers: benzopyranyl indoline and indole analogues.

K. Yi, H. Seo, J. Suh, 2003, European journal of medicinal chemistry.

KR-31466, a benzopyranylindol analog, attenuates hypoxic injury through mitochondrial K(ATP) channel and protein kinase C activation in heart-derived H9c2 cells.

K. Yi, Yi-Sook Jung, E. Baik, 2003, Journal of pharmacological sciences.

Characterization of cytochrome P450 enzymes and P‐glycoprotein involved in the metabolism and transport of a new anti‐angiogenic agent KR‐31831

K. Yi, H. Lee, H. Ji, 2005 .

Pharmacokinetics of a novel antiangiogenic agent KR‐31831 in rats

K. Yi, Sunkyung Lee, S. Yoo, 2005, Biopharmaceutics & drug disposition.

Determination of a Novel Antiangiogenic Agent KR‐31831 in Rat Plasma by Liquid Chromatography‐Tandem Mass Spectrometry

K. Yi, Sook jin Kim, H. Lee, 2004 .

Identification of a novel antiangiogenic agent; 4-(N-imidazol-2-ylmethyl)amino benzopyran analogues.

K. Yi, Guncheol Kim, Chong-Ock Lee, 2003, Bioorganic & medicinal chemistry letters.

2‐Heteroaryl Benzimidazole Derivatives as Melanin Concentrating Hormone Receptor 1 (MCH‐R1) Antagonists.

K. Yi, B. Lee, Kwang-Seok Oh, 2013 .

Synthesis and SAR of 5-aryl-furan-2-carboxamide derivatives as potent urotensin-II receptor antagonists.

K. Yi, Hye-Jin Park, B. Lee, 2019, Bioorganic & medicinal chemistry letters.

Indole‐2‐carboxamide Derivatives as Potent Urotensin‐II Receptor (UT) Antagonists

K. Yi, B. Lee, Kwang-Seok Oh, 2017 .

Effects of sabiporide, a specific Na+/H+ exchanger inhibitor, on neuronal cell death and brain ischemia

K. Yi, B. Lee, Yi-Sook Jung, 2005, Brain Research.

Cardioprotective effects of the novel Na+/H+ exchanger-1 inhibitor KR-32560 in a perfused rat heart model of global ischemia and reperfusion: Involvement of the Akt-GSK-3β cell survival pathway and antioxidant enzyme

K. Yi, S. Yoo, W. Choi, 2010, Archives of pharmacal research.

Pharmacological profile of KR-33028, a highly selective inhibitor of Na+/H+ exchanger.

K. Yi, Yi-Sook Jung, M. J. Kim, 2006, European journal of pharmacology.

KR-32570, a novel Na+/H+ exchanger-1 inhibitor, attenuates hypoxia-induced cell death through inhibition of intracellular Ca2+ overload and mitochondrial death pathway in H9c2 cells.

K. Yi, Yi-Sook Jung, M. J. Kim, 2005, European journal of pharmacology.

4-[(N-Imidazol-2-ylmethyl)anilino]pyranopyridine Analogues as Novel Antiangiogenic Agents.

K. Yi, Sunkyung Lee, C. Oh, 2005 .

Effects of KR-30035, a novel multidrug-resistance modulator, on the cardiovascular system of rats in vivo and on the cell cycle of human cancer cells in vitro

K. Yi, B. Lee, S. Yoo, 2000, Anti-cancer drugs.

A urotensin II receptor antagonist, KR36676, decreases vascular remodeling and inflammation in experimental pulmonary hypertension.

K. Yi, J. H. Lee, H. Seo, 2016, International immunopharmacology.

Synthesis and SAR of thieno[3,2-b]pyridinyl urea derivatives as urotensin-II receptor antagonists.

K. Yi, B. Lee, Kwang-Seok Oh, 2014, Bioorganic & medicinal chemistry letters.

A novel imidazo[1,5-b]isoquinolinone derivative, U63A05, inhibits Syk activation in mast cells to suppress IgE-mediated anaphylaxis in mice.

K. Yi, Hye-Jin Park, D. Park, 2011, Journal of pharmacological sciences.

The orally active urotensin receptor antagonist, KR36676, attenuates cellular and cardiac hypertrophy

C. H. Park, K. Yi, H. Seo, 2015, British journal of pharmacology.

KR-39038, a Novel GRK5 Inhibitor, Attenuates Cardiac Hypertrophy and Improves Cardiac Function in Heart Failure

K. Yi, J. H. Lee, H. Seo, 2020, Biomolecules & therapeutics.

Cardioprotective effect of KR-33889, a novel PARP inhibitor, against oxidative stress-induced apoptosis in H9c2 cells and isolated rat hearts

K. Yi, Bokyung Kim, Hun-Jong Chung, 2017, Archives of pharmacal research.

Differential effects of the optical isomers of KR30031 on cardiotoxicity and on multidrug resistance reversal activity

K. Yi, Chong-Ock Lee, B. Lee, 2003, Anti-cancer drugs.

A novel anti-neuroinflammatory pyridylimidazole compound KR-31360.

K. Yi, K. Suk, Je-Yoel Cho, 2010, Biochemical pharmacology.

Identification of N-(5-(phenoxymethyl)-1,3,4-thiadiazol-2-yl)acetamide derivatives as novel protein tyrosine phosphatase epsilon inhibitors exhibiting anti-osteoclastic activity.

K. Yi, Seung Jun Kim, Hwangseo Park, 2018, Bioorganic & medicinal chemistry.

KR33426, [2-(2,5-dichlorophenyl)-5-methyloxazol-4yl]carbonylguanidine, is a novel compound to be effective on mouse systemic lupus erythematosus.

Young Yang, K. Yi, S. Han, 2011, European journal of pharmacology.

An increase in B cell apoptosis by interfering BAFF-BAFF-R interaction with small synthetic molecules.

K. Yi, E. Moon, Sunkyung Lee, 2011, International immunopharmacology.

KR-31762, a novel KATP channel opener, exerts cardioprotective effects by opening SarcKATP channels in rat models of ischemia/reperfusion-induced heart injury

K. Yi, H. Won, H. Seo, 2008, Archives of pharmacal research.

Cardioprotective effects of bms-180448, a prototype mitokatp channel opener, and the role of salvage kinases, in the rat model of global ischemia and reperfusion heart injury

K. Yi, Ju-Han Lee, Bokyung Kim, 2007, Archives of pharmacal research.

Cardioprotective Effects of [5-(2-Methyl-5-Fluorophenyl)furan-2-ylcarbonyl]guanidine (KR-32568) in an Anesthetized Rat Model of Ischemia and Reperfusion Heart Injury

K. Yi, Y. Yun, S. Yoo, 2005, Pharmacology.

KR-33028, a Novel Na + /H + Exchanger-1 Inhibitor, Attenuates Glutamate-Induced Apoptotic Cell Death through Maintaining Mitochondrial Function

K. Yi, B. Lee, Yi-Sook Jung, 2011 .

4-Aminophthalazin-1(2H)-one Derivatives as Melanin Concentrating Hormone Receptor 1 (MCH-R1) Antagonists

K. Yi, Nakjeong Kim, B. Lee, 2013 .

Synthesis and SAR study of pyrrolo[3,4-b]pyridin-7(6H)-one derivatives as melanin concentrating hormone receptor 1 (MCH-R1) antagonists.

K. Yi, Ji Young Kim, B. Lee, 2013, Bioorganic & medicinal chemistry letters.

4-arylphthalazin-1(2H)-one derivatives as potent antagonists of the melanin concentrating hormone receptor 1 (MCH-R1).

K. Yi, B. Lee, Kwang-Seok Oh, 2012, Bioorganic & medicinal chemistry letters.

Synthesis and Biological Evaluation of 4-Heteroaryl-2-amino-5-methylimidazole Analogs as NHE-1 Inhibitors

K. Yi, Sunkyung Lee, B. Lee, 2009 .

BMS-191095, a cardioselective mitochondrial katp opener, inhibits human platelet aggregation by opening mitochondrial katp channels

K. Yi, Y. Yun, S. Yoo, 2005, Archives of pharmacal research.

Effects of [5-(2-methoxy-5-fluorophenyl)furan-2-ylcarbonyl]guanidine (KR-32560), a novel sodium/hydrogen exchanger-1 inhibitor, on myocardial infarct size and ventricular arrhythmias in a rat model of ischemia/reperfusion heart injury.

K. Yi, Y. Yun, S. Yoo, 2005, Journal of pharmacological sciences.

Benzo[b]thiophene-2-carboxamide derivatives as potent urotensin-II receptor antagonists.

Simon S. Woo, K. Yi, B. Lee, 2016, Bioorganic & medicinal chemistry letters.

1,3,4‐Thiadiazol‐2‐amine Derivatives as Urotensin‐II Receptor (UT) Antagonists

K. Yi, B. Lee, Kwang-Seok Oh, 2015 .

Design, syntheses and biological evaluations of nonpeptidic caspase 3 inhibitors

K. Yi, Yong-Sam Jung, Sunkyung Lee, 2002 .

(2-Aryl-5-methylimidazol-4-ylcarbonyl)guanidines and (2-aryl-5-methyloxazol-4-ylcarbonyl)guanidines as NHE-1 inhibitors.

K. Yi, Sunkyung Lee, B. Lee, 2009, Bioorganic & medicinal chemistry letters.

Evaluation of anti-coccidial effects of 1-[4-(4-nitrophenoxy)phenyl]propane-1-one and identification of its potential target proteins in Toxoplasma gondii

K. Yi, Jae-Hoon Lee, Hyun Park, 2015, Archives of pharmacal research.

Determination of a selective Na+/H+ exchanger inhibitor, 4-cyano(benzo[b]thiophene-2-carbonyl)guanidine (KR-33028) in rat plasma by liquid chromatography-tandem mass spectrometry.

K. Yi, You Sun Kim, H. Lee, 2007, Biomedical chromatography : BMC.

A Novel and Orally Active Poly(ADP-Ribose) Polymerase Inhibitor, KR-33889 [2-[Methoxycarbonyl(4-methoxyphenyl) methylsulfanyl]-1H-benzimidazole-4-carboxylic Acid Amide], Attenuates Injury in in Vitro Model of Cell Death and in Vivo Model of Cardiac Ischemia

K. Yi, H. Seo, H. Koo, 2009, Journal of Pharmacology and Experimental Therapeutics.

1,1′-Thiocarbonyldi-2,2′-pyridone. A New Useful Reagent for Functional Group Conversions under Essentially Neutral Conditions.

K. Yi, Sunggak Kim, 1987 .

DI-2-pyridyl sulfite. A new useful reagent for the preparation of N-sulfinylamines, nitriles, isocyanides, and carbodiimides under mild conditions

K. Yi, Sunggak Kim, 1986 .

Di-2-Pyridyl thionocarbonate. A new reagent for the preparation of isothiocyanates and carbodiimides.

K. Yi, Sunggak Kim, 1985 .

3-Substituted-(5-arylfuran-2-ylcarbonyl)guanidines as NHE-1 inhibitors.

K. Yi, Sunkyung Lee, B. Lee, 2007, Bioorganic & medicinal chemistry letters.

Synthesis of 5‐Aryl and Vinyl Tetrazoles by the Palladium‐Catalyzed Cross‐Coupling Reaction.

K. Yi, S. Yoo, 1995 .

Synthesis and biological evaluation of 3-substituted-benzofuran-2-carboxylic esters as a novel class of ischemic cell death inhibitors.

K. Yi, Yun S. Lee, Eunhee Kim, 2010, Bioorganic & medicinal chemistry letters.

Catalytic enatioselective synthesis of (3S)-2,3-oxidosqualene

E. Corey, K. Yi, S. Matsuda, 1992 .

1,1'-Thiocarbonyldi-2,2'-pyridone. A new useful reagent for functional group conversions under essentially neutral conditions

K. Yi, Sunggak Kim, 1986 .

New Amino-protective Reagents for t-Butoxycarbonylation and Benzyloxycarbonylation of Amines and Amino Acids

K. Yi, Sunggak Kim, Jae In Lee, 1985 .

Solid phase synthesis of biphenyltetrazole derivatives

K. Yi, Jin-soo Seo, S. Yoo, 1997 .

Synthesis of 5-aryl and vinyl tetrazoles by the palladium-catalyzed cross-coupling reaction

K. Yi, S. Yoo, 1995 .

Introduction of Heterocycles at the 2-Position of Indoline as Ester Bioisosteres

K. Yi, Sunkyung Lee, S. Yoo, 2004 .

(5-Arylfuran-2-ylcarbonyl)guanidines as cardioprotectives through the inhibition of Na+/H+ exchanger isoform-1.

K. Yi, Sunkyung Lee, B. Lee, 2005, Journal of medicinal chemistry.

A Novel Urotensin II Receptor Antagonist, KR-36996 Inhibits Smooth Muscle Proliferation through ERK/ROS Pathway

K. Yi, Yi-Sook Jung, B. Lee, 2017, Biomolecules & therapeutics.

Blockade of Urotensin II Receptor Prevents Vascular Dysfunction

K. Yi, Yi-Sook Jung, B. Lee, 2016, Biomolecules & therapeutics.

A novel urotensin II receptor antagonist, KR‐36996, improved cardiac function and attenuated cardiac hypertrophy in experimental heart failure

K. Yi, H. Seo, B. Lee, 2017, European journal of pharmacology.

A novel urotensin II receptor antagonist, KR‐36676, prevents ABCA1 repression via ERK/IL‐1&bgr; pathway

K. Yi, Yi-Sook Jung, B. Lee, 2017, European journal of pharmacology.

Cardioprotective effect of KR-33889, a novel PARP inhibitor, against oxidative stress-induced apoptosis in H9c2 cells and isolated rat hearts

K. Yi, Hun-Jong Chung, Hwa-Sup Shin, 2017, Archives of Pharmacal Research.

4-Heteroaryl Phthalazin-1(2H)-one Derivatives as Potent Melanin Concentrating Hormone Receptor 1 (MCH-R1) Antagonists

K. Yi, B. Lee, K. E. Lee, 2012 .

In vitro metabolism of a new cardioprotective agent, KR-33028 in the human liver microsomes and cryopreserved human hepatocytes

K. Yi, Kwang-Hyeon Liu, Hyunmi Kim, 2005, Archives of pharmacal research.

Synthesis and SAR investigations of novel 2-arylbenzimidazole derivatives as melanin-concentrating hormone receptor 1 (MCH-R1) antagonists.

K. Yi, Nakjeong Kim, B. Lee, 2011, Bioorganic & medicinal chemistry letters.

5-AIQ inhibits H2O2-induced apoptosis through reactive oxygen species scavenging and Akt/GSK-3β signaling pathway in H9c2 cardiomyocytes.

K. Yi, Zhong-Ping Feng, Bokyung Kim, 2013, Toxicology and applied pharmacology.

Protective effect of KR-31378 on oxidative stress in cardiac myocytes

K. Yi, Yi-Sook Jung, E. Baik, 2005, Archives of pharmacal research.

A novel anti-ischemic ATP-sensitive potassium channel (K(ATP)) opener without vasorelaxation: N-(6-aminobenzopyranyl)-N'-benzyl-N' '-cyanoguanidine analogue.

K. Yi, H. Seo, H. S. Shin, 2001, Journal of medicinal chemistry.

Effects of KR-32570, a new sodium hydrogen exchanger inhibitor, on myocardial infarction and arrhythmias induced by ischemia and reperfusion.

K. Yi, Sunkyung Lee, B. Lee, 2005, European journal of pharmacology.

KR-31831, a new synthetic anti-ischemic agent, inhibits in vivo and in vitro angiogenesis

Hyun Seok Song, K. Yi, M. Son, 2006, Experimental & Molecular Medicine.

KR-31831, benzopyran derivative, inhibits VEGF-induced angiogenesis of HUVECs through suppressing KDR expression.

Hyun Seok Song, K. Yi, S. Yoo, 1992, International journal of oncology.

Evaluation of anti-coccidial effects of 1-[4-(4-nitrophenoxy)phenyl]propane-1-one and identification of its potential target proteins in Toxoplasma gondii

K. Yi, Hyun-Ok Song, Seon-Ju Yeo, 2014, Archives of Pharmacal Research.

Effects of KR‐33028, a novel Na+/H+ exchanger‐1 inhibitor, on ischemia and reperfusion‐induced myocardial infarction in rats and dogs

K. Yi, H. Seo, Sunkyung Lee, 2007, Fundamental & clinical pharmacology.

Effects of KR-33028, a novel Na+/H+ exchanger-1 inhibitor, on glutamate-induced neuronal cell death and ischemia-induced cerebral infarct

Min Goo Lee, K. Yi, B. Lee, 2009, Brain Research.

4-Substituted (benzo[b]thiophene-2-carbonyl)guanidines as novel Na+/H+ exchanger isoform-1 (NHE-1) inhibitors.

K. Yi, Sunkyung Lee, B. Lee, 2005, Bioorganic & medicinal chemistry letters.

Effects of KR-32570, a new Na+/H+ exchanger inhibitor, on functional and metabolic impairments produced by global ischemia and reperfusion in the perfused rat heart.

K. Yi, H. Seo, Sunkyung Lee, 2005, European journal of pharmacology.

Antiplatelet activity of [5-(2-methoxy-5-chlorophenyl)furan-2-ylcarbonyl]guanidine (KR-32570), a novel sodium/hydrogen exchanger-1 and its mechanism of action

K. Yi, Y. Yun, Yong-ri Jin, 2006, Archives of pharmacal research.

Synthesis and photochromic properties of phenanthropyran derivative substituted with styryl group

K. Yi, Guncheol Kim, Nakjeong Kim, 2005 .

Computational studies of COX-2 inhibitors: 3D-QSAR and docking.

Chong Hak Chae, Sung-Eun Yoo, Kyung-Lae Park, 2004, Bioorganic & medicinal chemistry.

Synthesis and structure-activity relationship of naphtho[1,2-b]furan-2-carboxamide derivatives as melanin concentrating hormone receptor 1 antagonists.

K. Yi, B. Lee, K. Oh, 2013, Chemical & pharmaceutical bulletin.