D. Mikulecky

发表

Application of network thermodynamics to the computer modeling of the pharmacology of anticancer agents: a network model for methotrexate action as a comprehensive example.

J. White, D. Mikulecky, 1981, Pharmacology & therapeutics.

SPICE2 NETWORK THERMODYNAMIC SIMULATION OF ANTIFOLATE EFFECTS ON PURINE AND PYRIMIDINE BIOSYNTHESIS: EXPLORING THE ROLE OF TETRAHYDROFOLATE COFACTOR DEPLETION VERSUS DIHYDROFOLATE FEEDBACK INHIBITION

D. C. Mikulecky, D. Mikulecky, R. Seither, 1990 .

Even More than Life Itself: Beyond Complexity

D. Mikulecky, 2011 .

Complexity, communication between cells, and identifying the functional components of living systems: Some observations

D. Mikulecky, 1996, Acta biotheoretica.

Determination of Urea Permeability in Red Cells by Minimum Method

A. K. Solomon, D. Mikulecky, G. T. Rich, 1970, The Journal of general physiology.

Transcapillary solute exchange. A comparison of the Kedem-Katchalsky convection-diffusion equations with the rigorous nonlinear equations for this special case.

S. R. Thomas, D. Mikulecky, S. Thomas, 1978, Microvascular research.

Topological determinants of dynamic molecular properties: a network thermodynamic approach

D. Mikulecky, 1995 .

GROWTH MESSAGES IN PLANTS: PRINCIPLE OF A POSSIBLE MODELLING, AND FURTHER EXPERIMENTAL CHARACTERISTICS

D. Mikulecky, M. Thellier, M. Desbiez, 1994 .

Dilute solution approximation and generalization of the reflection coefficient method of describing volume and solute flows.

D. Mikulecky, 1973, Biophysical journal.

More than Life Itself : Beyond Complexity

D. Mikulecky, 2010 .

Causality and Complexity: The Myth of Objectivity in Science

D. Mikulecky, 2007, Chemistry & biodiversity.

The Imbalance Between Experiment and Theory in Biology: The Need for Theory-Directed Modeling

D. Mikulecky, M. L. Fidelman, 1986 .

A continuum mechanical approach to the flow equations for membrane transport. I. Water flow.

D. Mikulecky, 1972, Biophysical journal.

A network thermodynamic model of salt and water flow across the kidney proximal tubule.

D C Mikulecky, S. R. Thomas, D. Mikulecky, 1978, The American journal of physiology.

A nonlinear boundary value problem arising in the structure of the double layer at an enzymatic surface

D. Mikulecky, J. Desimone, J. A. Pennline, 1977 .

Folate-pool interconversions and inhibition of biosynthetic processes after exposure of L1210 leukemia cells to antifolates. Experimental and network thermodynamic analyses of the role of dihydrofolate polyglutamylates in antifolate action in cells.

D C Mikulecky, D. Mikulecky, R. Seither, 1989, The Journal of biological chemistry.

Sodium - Potassium Ion Exchange Equilibria for Fragmented Human Erythrocyte Ghosts

D. Mikulecky, 1965, Nature.

PHOSPHOLIPID-CHOLESTEROL MEMBRANE MODEL. I. CORRELATION OF RESISTANCE WITH ION CONTENT. II. CATION EXCHANGE PROPERTIES. 3. EFFECT OF CA ON SALT PERMEABILITY. IV. CA-K UPTAKE BY SONICALLY FRAGMENTED ERYTHROCYTE GHOSTS.

D. Mikulecky, J. Tobias, 1964, Journal of cellular and comparative physiology.

Network thermodynamic modeling of hormone regulation of active Na+ transport in cultured renal epithelium (A6).

D C Mikulecky, D. Mikulecky, M L Fidelman, 1986, The American journal of physiology.

Exploration of apical sodium transport mechanisms in an epithelial model by network thermodynamic simulation of the effect of mucosal sodium depletion: II. An apical sodium channel and amiloride blocking.

D C Mikulecky, D. Mikulecky, S. Thomas, 1986, Journal of theoretical biology.

Exploration of apical sodium transport mechanisms in an epithelial model by network thermodynamic simulation of the effect of mucosal sodium depletion: I. Comparison of three different apical sodium permeability expressions.

D C Mikulecky, S. R. Thomas, D. Mikulecky, 1986, Journal of theoretical biology.

Network Thermodynamics and Complexity: A Transition to Relational Systems Theory

Donald C. Mikulecky, D. Mikulecky, 2001, Comput. Chem..

A network thermodynamic two-port element to represent the coupled flow of salt and current. Improved alternative for the equivalent circuit.

D C Mikulecky, D. Mikulecky, 1979, Biophysical journal.

A simple network thermodynamic method for series-parallel coupled flows: II. The non-linear theory, with applications to coupled solute and volume flow in a series membrane.

D C Mikulecky, D. Mikulecky, 1977, Journal of theoretical biology.

The Choice of Reference Frame in the Treatment of Membrane Transport by Nonequilibrium Thermodynamics

D. Mikulecky, S. Caplan, 1966 .

Global flow equations for membrane transport from local equations of motion: I. The general case for (n−1) nonelectrolyte solutes plus water

D. Mikulecky, 1978, Bulletin of mathematical biology.

Dynamic simulation of pharmacokinetic systems using the electrical circuit analysis program SPICE2.

K M Thakker, J H Wood, D C Mikulecky, 1982, Computer programs in biomedicine.

A network thermodynamic model of glomerular dynamics: application in the rat.

D E Oken, D C Mikulecky, D. Mikulecky, 1981, Kidney international.

Network thermodynamic approach compartmental analysis. Na+ transients in frog skin.

E G Huf, D C Mikulecky, S. R. Thomas, 1979, Biophysical journal.

Modelling and simulation of the nonlinear dose-plasma concentration response of phenylbutazone on periodic multiple oral dosing: A mechanistic approach

Donald C. Mikulecky, D. Mikulecky, K. Thakker, 1986 .

Modeling intestinal absorption and other nutrition-related processes using PSPICE and STELLA.

D. Mikulecky, 1990, Journal of pediatric gastroenterology and nutrition.

Nonlinear and philosophical issues in biological modelling: When is a mechanism not a mechanism? The network thermodynamic approach to complex systems

D. C. Mikulecky, D. Mikulecky, 1988 .

The Circle That Never Ends: Can Complexity be Made Simple?

Donald C. Mikulecky, D. Mikulecky, 2005 .

Methods of Mathematical Modelling

Donald C. Mikulecky, Dieter Walz, S. Roy Caplan, 1995 .

Robert Rosen: the well‐posed question and its answer ‐ why are organisms different from machines?

Donald C. Mikulecky, D. Mikulecky, 2000 .

A simple network thermodynamic method for modeling series-parallel coupled flows. I. The linear case.

D C Mikulecky, J S Shiner, D. Mikulecky, 1977, Journal of theoretical biology.

Network thermodynamic simulation of biological systems: An overview

D. C. Mikulecky, D. Mikulecky, 1982 .

The Emergence of Complexity: Science Coming of Age Or Science Growing Old?

Donald C. Mikulecky, D. Mikulecky, 2001, Comput. Chem..

Network thermodynamics: a simulation and modeling method based on the extension of thermodynamic thinking into the realm of highly organized systems

Donald C. Mikulecky, D. Mikulecky, 1984 .

The simple model of adipocyte hexose transport. Kinetic features, effect of insulin, and network thermodynamic computer simulations.

D C Mikulecky, D. Mikulecky, J. M. May, 1982, The Journal of biological chemistry.

COMPLEXITY SCIENCE AS AN ASPECT OF THE COMPLEXITY OF SCIENCE

Donald C. Mikulecky, D. Mikulecky, 2007 .

The application of electrical network theory to the analysis and simulation of dynamic physiological systems

D. C. Mikulecky, D. Mikulecky, 1991, IEEE Proceedings of the SOUTHEASTCON '91.

The role of the reference state in nonlinear kinetic models: Network thermodynamics leads to a linear and reciprocal coordinate system far from equilibrium

D. C. Mikulecky, D. Mikulecky, F. Sauer, 1988 .

A network thermodynamic approach to Hill and King–Altman reaction–diffusion kinetics

D. C. Mikulecky, S. Roy Caplan, Barry Bunow, 1985 .

Determination of Urea Permeability in Red Cells by Minimum Method the Journal of General Physiology

D. Mikulecky, R. I. Sha 'afi, G. T. Rich, 2022 .

n-ports: What are they good for?

D. C. Mikulecky, D. Mikulecky, 1994 .

The reference state and the metric structure of biological networks: a network thermodynamic study

D. Mikulecky, 1989, Proceedings. IEEE Energy and Information Technologies in the Southeast'.

Some applications of the current divider principle to physical networks: a network thermodynamic approach to a 'biological' circuit theory

D. C. Mikulecky, D. Mikulecky, 1988, Conference Proceedings '88., IEEE Southeastcon.

A New Approach to a Theory of Management: Manage the Real Complex System, Not its Model

Donald C. Mikulecky, D. Mikulecky, 2010 .

Compartmental analysis of the Na+ flux ratio with application to data on frog skin epidermis.

E G Huf, D C Mikulecky, D. Mikulecky, 1985, Journal of theoretical biology.

Some network thermodynamic models of coupled, dynamic physiological systems

D. C. Mikulecky, S. R. Thomas, S. R. Thomas, 1979 .