Shunqi Yan

发表

Small molecule activation of PKM2 in cancer cells induces serine auxotrophy.

L. Cantley, C. Kung, J. Hixon, 2012, Chemistry & biology.

Identification of isothiazole-4-carboxamidines derivatives as a novel class of allosteric MEK1 inhibitors.

Shunqi Yan, C. Varaprasad, D. Barawkar, 2006, Bioorganic & medicinal chemistry letters.

Structure-based design of a novel thiazolone scaffold as HCV NS5B polymerase allosteric inhibitors.

Gary Larson, Shunqi Yan, J. Wu, 2006, Bioorganic & medicinal chemistry letters.

Novel thiazolones as HCV NS5B polymerase allosteric inhibitors: Further designs, SAR, and X-ray complex structure.

Gary Larson, Shunqi Yan, J. Wu, 2007, Bioorganic & medicinal chemistry letters.

Structure-activity relationship (SAR) studies of quinoxalines as novel HCV NS5B RNA-dependent RNA polymerase inhibitors.

Gary Larson, Shunqi Yan, J. Wu, 2007, Bioorganic & medicinal chemistry letters.

Isothiazoles as active-site inhibitors of HCV NS5B polymerase.

Shunqi Yan, J. Wu, R. Hamatake, 2006, Bioorganic & medicinal chemistry letters.

Identification and structure-activity relationships of substituted pyridones as inhibitors of Pim-1 kinase.

I. W. Cheney, Shunqi Yan, J. Wu, 2007, Bioorganic & medicinal chemistry letters.

Absolute kinetics of phenylchlorocarbene CH insertion reactions

Shunqi Yan, R. Moss, 1998 .

Ab Initio Electronic Structure Calculations on Chlorocarbene−Ethylene and Chlorocarbene−Benzene Complexes

Shunqi Yan, R. Moss, K. Krogh-Jespersen, 1999 .

Targeted Inhibition of Mutant IDH2 in Leukemia Cells Induces Cellular Differentiation

Fang Wang, Erica Hansen, Francesco G. Salituro, 2013, Science.

Acquired Resistance to the TRK Inhibitor Entrectinib in Colorectal Cancer.

Gang Li, R. Shoemaker, Shunqi Yan, 2015, Cancer discovery.

Discovery of the First Potent Inhibitors of Mutant IDH1 That Lower Tumor 2-HG in Vivo.

S. Gross, Shunqi Yan, J. Saunders, 2012, ACS medicinal chemistry letters.

Antitumor Activity of RXDX-105 in Multiple Cancer Types with RET Rearrangements or Mutations

M. Ladanyi, A. Drilon, Shunqi Yan, 2016, Clinical Cancer Research.

Identification of novel, selective and potent Chk2 inhibitors.

Shunqi Yan, Huanming Chen, J. Wu, 2007, Bioorganic & medicinal chemistry letters.

Using cyclooxygenase-2 inhibitors as molecular platforms to develop a new class of apoptosis-inducing agents.

Shunqi Yan, Ho-pi Lin, Xueqin Song, 2002, Journal of the National Cancer Institute.

MODULATION OF CARBENIC REACTIVITY BY PI -COMPLEXATION TO AROMATICS

Shunqi Yan, R. Moss, K. Krogh-Jespersen, 1998 .

RDEA119: A potent and highly selective MEK inhibitor for the treatment of cancer

Shunqi Yan, R. Hamatake, G. Larson, 2007 .

Identification and structure-activity relationships of substituted pyridones as inhibitors of Pim-1 kinase.

I. W. Cheney, Shunqi Yan, R. Hamatake, 2007, Bioorganic & medicinal chemistry letters.

Structure-based library design in efficient discovery of novel inhibitors.

Shunqi Yan, Robert Selliah, Shunqi Yan, 2011, Methods in molecular biology.