I. Barrett

发表

Specific synthetic lethal killing of RAD54B-deficient human colorectal cancer cells by FEN1 silencing

P. Hieter, K. McManus, I. Barrett, 2009, Proceedings of the National Academy of Sciences.

Lead identification of conformationally restricted benzoxepin type combretastatin analogs: synthesis, antiproliferative activity, and tubulin effects

I. Barrett, D. Zisterer, L. Greene, 2010, Journal of enzyme inhibition and medicinal chemistry.

Synthesis, biological evaluation, structural-activity relationship, and docking study for a series of benzoxepin-derived estrogen receptor modulators.

Andrew J. S. Knox, Andrew J S Knox, Mary J Meegan, 2008, Bioorganic & medicinal chemistry.

Benzothiepin-derived molecular scaffolds for estrogen receptor modulators: synthesis and antagonistic effects in breast cancer cells

Andrew J. S. Knox, I. Barrett, D. Zisterer, 2007, Journal of enzyme inhibition and medicinal chemistry.

Chromatid cohesion defects may underlie chromosome instability in human colorectal cancers

G. Parmigiani, K. Kinzler, B. Vogelstein, 2008, Proceedings of the National Academy of Sciences.

YB-1 evokes susceptibility to cancer through cytokinesis failure, mitotic dysfunction, and HER2 amplification

P. Hieter, I. Barrett, C. Maxwell, 2011, Oncogene.

Lead Optimization of Benzoxepin-Type Selective Estrogen Receptor (ER) Modulators and Downregulators with Subtype-Specific ERα and ERβ Activity.

Andrew J. S. Knox, I. Barrett, D. Zisterer, 2017, Journal of medicinal chemistry.

Synthetic Lethality of Cohesins with PARPs and Replication Fork Mediators

P. Hieter, Payal Sipahimalani, I. Barrett, 2012, PLoS genetics.

An Evolutionarily Conserved Synthetic Lethal Interaction Network Identifies FEN1 as a Broad-Spectrum Target for Anticancer Therapeutic Development

P. Hieter, K. McManus, I. Barrett, 2013, PLoS genetics.

R-loop-mediated genome instability in mRNA cleavage and polyadenylation mutants.

P. Hieter, Payal Sipahimalani, I. Barrett, 2012, Genes & development.

polyadenylation mutants R-loop-mediated genome instability in mRNA cleavage and Material Supplemental

P. Hieter, Payal Sipahimalani, I. Barrett, 2012 .

Genome-Wide Synthetic Lethal Screens Identify an Interaction Between the Nuclear Envelope Protein, Apq12p, and the Kinetochore in Saccharomyces cerevisiae

P. Hieter, I. Barrett, V. Measday, 2005, Genetics.

3 Aminobenzamide, an inhibitor of poly ADP-ribose polymerase, decreases the frequency of alkaline labile lesions and increases growth in human fibroblasts exposed to 3-methyl 4-nitroquinoline 1-oxide

I. Barrett, R. Waters, F. Ramsay, 1982 .

R-loop-mediated genome instability in mRNA cleavage and polyadenylation mutants.

P. Hieter, Payal Sipahimalani, I. Barrett, 2012, Genes & development.