M. Antoch

发表

Circadian and CLOCK-controlled regulation of the mouse transcriptome and cell proliferation

Erin L. McDearmon, B. H. Miller, J. Takahashi, 2007, Proceedings of the National Academy of Sciences.

Coordinated Transcription of Key Pathways in the Mouse by the Circadian Clock

B. H. Miller, A. Su, P. Schultz, 2002, Cell.

BMAL1-dependent regulation of the mTOR signaling pathway delays aging

M. Antoch, R. Kondratov, Rohini V. Khapre, 2014, Aging.

Metabolic clock generates nutrient anticipation rhythms in mTOR signaling

M. Antoch, R. Kondratov, Rohini V. Khapre, 2014, Aging.

Positional syntenic cloning and functional characterization of the mammalian circadian mutation tau.

J. Takahashi, M. Antoch, M. Menaker, 2000, Science.

Positional Cloning of the Mouse Circadian Clock Gene

Minoru Tanaka, D. P. King, J. Kornhauser, 1997, Cell.

Functional Identification of the Mouse Circadian Clock Gene by Transgenic BAC Rescue

Anne-Marie Chang, D. P. King, J. Takahashi, 1997, Cell.

The Murine Cone Photoreceptor A Single Cone Type Expresses Both S and M Opsins with Retinal Spatial Patterning

M. Antoch, M. Applebury, L. C. Baxter, 2000, Neuron.

Senescent cells expose and secrete an oxidized form of membrane-bound vimentin as revealed by a natural polyreactive antibody

A. Osterman, M. Antoch, A. Gudkov, 2017, Proceedings of the National Academy of Sciences.

Pharmacological modulators of the circadian clock as potential therapeutic drugs.

M. Antoch, M. Chernov, 2009, Mutation research.

Identification of a blood test-based biomarker of aging through deep learning of aging trajectories in large phenotypic datasets of mice

M. Antoch, A. Gudkov, P. Fedichev, 2020, bioRxiv.

A small molecule inhibitor of p53 stimulates amplification of hematopoietic stem cells but does not promote tumor development in mice

M. Antoch, P. Komarov, A. Gudkov, 2010, Cell cycle.

Physiological frailty index (PFI): quantitative in-life estimate of individual biological age in mice

M. Antoch, A. Hutson, A. Gudkov, 2017, Aging.

Circadian Rhythm Disruption Increases Tumor Growth Rate and Accumulation of Myeloid-Derived Suppressor Cells

M. Antoch, E. Repasky, H. Mohammadpour, 2022, Advanced biology.

Circadian Clock Genes as Modulators of Sensitivity to Genotoxic Stress

J. Takahashi, M. Antoch, R. Kondratov, 2005, Cell cycle.

New nanoformulation of rapamycin Rapatar extends lifespan in homozygous p53−/− mice by delaying carcinogenesis

M. Antoch, A. Gudkov, M. Blagosklonny, 2012, Aging.

Pharmacological modulators of the circadian clock as potential therapeutic drugs: focus on genotoxic/anticancer therapy.

M. Antoch, R. Kondratov, 2013, Handbook of experimental pharmacology.

Unsupervised learning of aging principles from longitudinal data

M. Antoch, A. Gudkov, P. Fedichev, 2022, Nature Communications.

Daily Time of Radiation Treatment Is Associated with Subsequent Oral Mucositis Severity during Radiotherapy in Head and Neck Cancer Patients

Anurag K. Singh, M. Antoch, A. Hutson, 2020, Cancer Epidemiology, Biomarkers & Prevention.

Rapamycin extends lifespan and delays tumorigenesis in heterozygous p53+/− mice

M. Antoch, A. Gudkov, E. Komarova, 2012, Aging.

On the role of transducin GTPase in the quenching of a phosphodiesterase cascade of vision

M. Antoch, V. Arshavsky, P. P. Philippov, 1987, FEBS letters.

OT-82, a novel anticancer drug candidate that targets the strong dependence of hematological malignancies on NAD biosynthesis

M. Antoch, P. Komarov, A. Gudkov, 2020, Leukemia.

Early aging and age-related pathologies in mice deficient in BMAL1, the core componentof the circadian clock.

M. Antoch, R. Kondratov, A. Kondratova, 2006, Genes & development.

Transducin GTPase provides for rapid quenching of the cGMP cascade in rod outer segments

M. Antoch, V. Arshavsky, P. P. Philippov, 1989, FEBS letters.

LINE1 Derepression in Aged Wild-Type and SIRT6-Deficient Mice Drives Inflammation.

Margarita V. Meer, V. Gladyshev, M. Antoch, 2019, Cell metabolism.

Inhibition of retrotransposition improves health and extends lifespan of SIRT6 knockout mice

M. Antoch, S. Helfand, N. Neretti, 2018 .

Superior cancer preventive efficacy of low versus high dose of mTOR inhibitor in a mouse model of prostate cancer

Bryan M. Gillard, E. Karasik, M. T. Moser, 2020, Oncotarget.

Antioxidant N-acetyl-L-cysteine ameliorates symptoms of premature aging associated with the deficiency of the circadian protein BMAL1

M. Antoch, R. Kondratov, A. Kondratova, 2009, Aging.

The mouse Clock locus: sequence and comparative analysis of 204 kb from mouse chromosome 5.

J. Takahashi, M. Antoch, L. Wilsbacher, 2000, Genome research.

Innate sensitivity to stress facilitates inflammation, alters metabolism and shortens lifespan in a mouse model of social hierarchy

M. Antoch, A. Pinhasov, I. Michaelevski, 2019, Aging.

Circadian clock proteins control adaptation to novel environment and memory formation

M. Antoch, R. Kondratov, Anna A.Kondratova, 2010, Aging.

A serine cluster mediates BMAL1-dependent CLOCK phosphorylation and degradation

M. Antoch, K. Kuropatwinski, Molly Schumer, 2009, Cell cycle.

Circadian Proteins and Genotoxic Stress Response

M. Antoch, R. Kondratov, 2010, Circulation research.

Circadian Proteins and Genotoxic Stress Circadian Clocks and the Transcriptome Functions of the Cardiomyocyte Circadian Clock Circadian Clocks and Vascular Function Molecular Clocks and Cardiometabolic Syndrome

M. Antoch, R. Kondratov, M. Young, 2009 .

The role of mammalian circadian proteins in normal physiology and genotoxic stress responses.

M. Antoch, R. Kondratov, V. Gorbacheva, 2007, Current topics in developmental biology.

Circadian sensitivity to the chemotherapeutic agent cyclophosphamide depends on the functional status of the CLOCK/BMAL1 transactivation complex.

J. Takahashi, M. Antoch, Renliang Zhang, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Daily rhythms are retained both in spontaneously developed sarcomas and in xenografts grown in immunocompromised SCID mice

M. Antoch, K. Kuropatwinski, I. Toshkov, 2014, Chronobiology international.

Core circadian protein CLOCK is a positive regulator of NF-κB–mediated transcription

M. Antoch, A. Gudkov, K. Kuropatwinski, 2012, Proceedings of the National Academy of Sciences.

Rapamycin extends maximal lifespan in cancer-prone mice.

M. Antoch, V. Anisimov, I. Popovich, 2010, The American journal of pathology.

Deficiency in PER proteins has no effect on the rate of spontaneous and radiation-induced carcinogenesis

M. Antoch, K. Kuropatwinski, I. Toshkov, 2013, Cell cycle.

Disruption of the circadian clock due to the Clock mutation has discrete effects on aging and carcinogenesis

M. Antoch, R. Kondratov, A. Nikitin, 2008, Cell cycle.

Circadian proteins in the regulation of cell cycle and genotoxic stress responses.

M. Antoch, R. Kondratov, 2007, Trends in cell biology.

The clock proteins, aging, and tumorigenesis.

M. Antoch, R. Kondratov, 2007, Cold Spring Harbor symposia on quantitative biology.

BMAL1-dependent circadian oscillation of nuclear CLOCK: posttranslational events induced by dimerization of transcriptional activators of the mammalian clock system.

M. Antoch, A. Gudkov, R. Kondratov, 2003, Genes & development.

Selenium is a modulator of circadian clock that protects mice from the toxicity of a chemotherapeutic drug via upregulation of the core clock protein, BMAL1

M. Antoch, A. Gudkov, Y. Rustum, 2011, Oncotarget.

Posttranslational Regulation of Circadian Transcriptional Clock (NPAS2)/BMAL1 Complex by Cryptochromes

M. Antoch, R. Kondratov, A. Kondratova, 2006, Cell cycle.

Dual role of the CLOCK/BMAL1 circadian complex in transcriptional regulation

M. Antoch, R. Kondratov, A. Kondratova, 2006, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Tissue-Specific Changes in Molecular Clocks During the Transition from Pregnancy to Lactation in Mice1

M. Antoch, K. Kuropatwinski, T. Casey, 2014, Biology of reproduction.

Mammalian Circadian Autoregulatory Loop A Timeless Ortholog and mPer1 Interact and Negatively Regulate CLOCK-BMAL1-Induced Transcription

D. P. King, J. Takahashi, C. Weitz, 1998, Neuron.

The mouse Clock mutation reduces circadian pacemaker amplitude and enhances efficacy of resetting stimuli and phase-response curve amplitude.

Anne-Marie Chang, Ethan D Buhr, J. Takahashi, 2006, Proceedings of the National Academy of Sciences of the United States of America.

Deficiency in core circadian protein Bmal1 is associated with a prothrombotic and vascular phenotype

M. Antoch, E. Podrez, T. Byzova, 2011, Journal of cellular physiology.

Immune checkpoint protein VSIG4 as a biomarker of aging in murine adipose tissue

M. Antoch, A. Gudkov, S. Vujcic, 2020, Aging cell.

The orphan receptor Rev-erbα gene is a target of the circadian clock pacemaker

Gérard Triqueneaux, Joseph S. Takahashi, Vincent Laudet, 2004 .

Evidence for circadian regulation of activating transcription factor 5 but not tyrosine hydroxylase by the chromaffin cell clock.

M. Antoch, S. Ojeda, H. Urbanski, 2007, Endocrinology.

The orphan receptor Rev-erbalpha gene is a target of the circadian clock pacemaker.

Gérard Triqueneaux, Vincent Laudet, Franck Delaunay, 2004, Journal of molecular endocrinology.