A. Strasser

发表

Aminobenzimidazoles and Structural Isomers as Templates for Dual‐Acting Butyrylcholinesterase Inhibitors and hCB2R Ligands To Combat Neurodegenerative Disorders

Dominik Dolles, Martin Nimczick, M. Scheiner, 2016, ChemMedChem.

Modelling of GPCRs

Hans-Joachim Wittmann, A. Strasser, 2013, Springer Netherlands.

New insights into the cross-linking and degradation mechanism of Diels-Alder hydrogels.

Hans-Joachim Wittmann, A. Strasser, A. Goepferich, 2015, Journal of materials chemistry. B.

Optical properties of tris(cyclopentadienyl)gadolinium. Luminescence from an interligand triplet under ambient conditions

A. Strasser, A. Vogler, 2003 .

Phosphorescence of gadolinium(III) chelates under ambient conditions

A. Strasser, A. Vogler, 2004 .

Species-dependent activities of G-protein-coupled receptor ligands: lessons from histamine receptor orthologs.

Hans-Joachim Wittmann, A. Strasser, R. Seifert, 2013, Trends in pharmacological sciences.

Dibenzo[b,f][1,4]oxazepines and dibenzo[b,e]oxepines: Influence of the chlorine substitution pattern on the pharmacology at the H1R, H4R, 5-HT2AR and other selected GPCRs.

Hans-Joachim Wittmann, A. Strasser, P. Gmeiner, 2016, Pharmacological research.

Molecular and cellular analysis of human histamine receptor subtypes.

A. Strasser, R. Seifert, A. Buschauer, 2013, Trends in pharmacological sciences.

Molecular Modelling Approaches for the Analysis of Histamine Receptors and Their Interaction with Ligands.

Hans-Joachim Wittmann, A. Strasser, 2017, Handbook of experimental pharmacology.

Enhanced photoreactivity of zirconium(IV) and hafnium(IV) porphyrin complexes promoted by water molecules

A. Strasser, G. Knör, 2005 .

Shining light on the histamine H2 receptor: Synthesis of carbamoylguanidine-type agonists as a pharmacological tool to study internalization.

A. Strasser, T. Littmann, Katharina Tropmann, 2021, Bioorganic & medicinal chemistry letters.

Striking differences of action of lisuride stereoisomers at histamine H1 receptors

A. Strasser, R. Seifert, H. Pertz, 2006, Naunyn-Schmiedeberg's Archives of Pharmacology.

Microsoft Word-47256044-file00

R. Thurmond, A. Strasser, R. Seifert, 2010 .

Force Fields

Hans-Joachim Wittmann, A. Strasser, 2020, War at the Speed of Light.

LigPath: a module for predictive calculation of a ligand’s pathway into a receptor-application to the gpH1 - receptor

Hans-Joachim Wittmann, A. Strasser, 2006, Journal of molecular modeling.

Intraligand phosphorescence of lead(II) β-diketonates under ambient conditions

A. Strasser, A. Vogler, 2004 .

Optical properties of thallium(I), lead(II) and bismuth(III) hexafluoroacetylacetonates. Intraligand phosphorescence under ambient conditions

A. Strasser, A. Vogler, 2004 .

Intraligand fluorescence and phosphorescence of tris(pyrazolyl) hydridoborate complexes

A. Strasser, A. Vogler, H. Kunkely, 2008 .

Synthesis, biological evaluation, and computational studies of Tri- and tetracyclic nitrogen-bridgehead compounds as potent dual-acting AChE inhibitors and hH3 receptor antagonists.

Martin Nimczick, C. Sotriffer, Hans-Joachim Wittmann, 2014, ACS chemical neuroscience.

Conformational Restriction and Enantioseparation Increase Potency and Selectivity of Cyanoguanidine-Type Histamine H4 Receptor Agonists.

Hans-Joachim Wittmann, A. Strasser, A. Buschauer, 2016, Journal of medicinal chemistry.

Molecular modeling and QSAR-based design of histamine receptor ligands

A. Strasser, 2009, Expert opinion on drug discovery.

Molecularmodelingand QSAR-baseddesignofhistamine receptorligands

A. Strasser, 2009 .

Nanofibers resulting from cooperative electrostatic and hydrophobic interactions between peptides and polyelectrolytes of opposite charge.

Hans-Joachim Wittmann, A. Strasser, J. Engel, 2011, Langmuir : the ACS journal of surfaces and colloids.

Pharmacological Profile of Histaprodifens at Four Recombinant Histamine H1 Receptor Species Isoforms

Hans-Joachim Wittmann, A. Strasser, R. Seifert, 2008, Journal of Pharmacology and Experimental Therapeutics.

Influence of the N-terminus and the E2-loop onto the binding kinetics of the antagonist mepyramine and the partial agonist phenoprodifen to H(1)R.

Hans-Joachim Wittmann, A. Strasser, R. Seifert, 2011, Biochemical pharmacology.

Mathematical analysis of the sodium sensitivity of the human histamine H3 receptor

Hans-Joachim Wittmann, A. Strasser, R. Seifert, 2014, In Silico Pharmacology.

Impact of the DRY Motif and the Missing “Ionic Lock” on Constitutive Activity and G-Protein Coupling of the Human Histamine H4 Receptor

A. Strasser, R. Seifert, E. Schneider, 2010, Journal of Pharmacology and Experimental Therapeutics.

Analysis of the activation mechanism of the guinea-pig Histamine H1-receptor

Hans-Joachim Wittmann, Andrea Straßer, Hans-Joachim Wittmann, 2007, J. Comput. Aided Mol. Des..

Interactions of recombinant human histamine H1, H2, H3, and H4 receptors with 34 antidepressants and antipsychotics

A. Strasser, R. Seifert, S. Dove, 2011, Naunyn-Schmiedeberg's Archives of Pharmacology.

Structural Requirements for Inverse Agonism and Neutral Antagonism of Indole-, Benzimidazole-, and Thienopyrrole-Derived Histamine H4 Receptor Ligands

Roland Seifert, Andrea Strasser, R. Thurmond, 2010, Journal of Pharmacology and Experimental Therapeutics.

Comparison of the pharmacological properties of human and rat histamine H(3)-receptors.

A. Strasser, R. Seifert, D. Schnell, 2010, Biochemical pharmacology.

Label-Free Investigations on the G Protein Dependent Signaling Pathways of Histamine Receptors

A. Strasser, A. Inoue, G. Bernhardt, 2021, International journal of molecular sciences.

A Dynamic, Split-Luciferase-Based Mini-G Protein Sensor to Functionally Characterize Ligands at All Four Histamine Receptor Subtypes

A. Strasser, G. Bernhardt, Steffen Pockes, 2020, International journal of molecular sciences.

Contribution of Binding Enthalpy and Entropy to Affinity of Antagonist and Agonist Binding at Human and Guinea Pig Histamine H1-Receptor

Hans-Joachim Wittmann, A. Strasser, R. Seifert, 2009, Molecular Pharmacology.

Competitive association binding kinetic assays: a new tool to detect two different binding orientations of a ligand to its target protein under distinct conditions?

Hans-Joachim Wittmann, A. Strasser, 2017, Naunyn-Schmiedeberg's Archives of Pharmacology.

Binding Kinetics and Pathways of Ligands to GPCRs.

Hans-Joachim Wittmann, A. Strasser, R. Seifert, 2017, Trends in pharmacological sciences.

Distinct interactions between the human adrenergic β2 receptor and Gαs—an in silico study

Hans-Joachim Wittmann, A. Strasser, 2010, Journal of molecular modeling.

Mepyramine-JNJ7777120-hybrid compounds show high affinity to hH(1)R, but low affinity to hH(4)R.

Hans-Joachim Wittmann, A. Strasser, S. Elz, 2011, Bioorganic & medicinal chemistry letters.

Structure-Dependent Deconjugation of Flavonoid Glucuronides by Human β-Glucuronidase – In Vitro and In Silico Analyses

Hans-Joachim Wittmann, A. Strasser, J. Heilmann, 2015, Planta Medica.

Loratadine and analogues: discovery and preliminary structure-activity relationship of inhibitors of the amino acid transporter B(0)AT2.

K. Wanner, G. Höfner, F. Holsboer, 2014, Journal of medicinal chemistry.

Specific Engineered G Protein Coupling to Histamine Receptors Revealed from Cellular Assay Experiments and Accelerated Molecular Dynamics Simulations

Christian A. Söldner, A. Strasser, Jinan Wang, 2021, International journal of molecular sciences.

In silico analysis of the histaprodifen induced activation pathway of the guinea-pig histamine H1-receptor

Hans-Joachim Wittmann, Andrea Straßer, Hans-Joachim Wittmann, 2010, J. Comput. Aided Mol. Des..

Molecular determinants for the high constitutive activity of the human histamine H4 receptor: functional studies on orthologues and mutants

A. Strasser, R. Seifert, A. Buschauer, 2015, British journal of pharmacology.

Paradoxical Stimulatory Effects of the “Standard” Histamine H4-Receptor Antagonist JNJ7777120: the H4 Receptor Joins the Club of 7 Transmembrane Domain Receptors Exhibiting Functional Selectivity

A. Strasser, R. Seifert, A. Buschauer, 2011, Molecular Pharmacology.

Interactions of Histamine H1-Receptor Agonists and Antagonists with the Human Histamine H4-Receptor

A. Strasser, R. Seifert, D. Neumann, 2009, Molecular Pharmacology.

2,4-Diaminopyrimidines as dual ligands at the histamine H1 and H4 receptor-H1/H4-receptor selectivity.

Hans-Joachim Wittmann, A. Strasser, S. Elz, 2016, Bioorganic & medicinal chemistry letters.

Theoretical studies on the interaction of partial agonists with the 5-HT2A receptor

Stefan Dove, Andrea Straßer, Ralf Heim, 2011, J. Comput. Aided Mol. Des..

Modulation of GPCRs by monovalent cations and anions

Hans-Joachim Wittmann, A. Strasser, R. Seifert, 2015, Naunyn-Schmiedeberg's Archives of Pharmacology.

Sodium binding to hH3R and hH4R — a molecular modeling study

Hans-Joachim Wittmann, A. Strasser, R. Seifert, 2014, Journal of Molecular Modeling.

Role of the second and third extracellular loops of the histamine H4 receptor in receptor activation

A. Strasser, R. Seifert, A. Buschauer, 2011, Naunyn-Schmiedeberg's Archives of Pharmacology.

Concept and Definitions in Cyclostratigraphy (Second Report of the Cyclostratigraphy Working Group)

A. Strasser, W. Schwarzacher, Fredrik Hilgen, 2004 .

Interactions of recombinant human histamine H1, H2, H3, and H4 receptors with 34 antidepressants and antipsychotics

A. Strasser, R. Seifert, S. Dove, 2012, Naunyn-Schmiedeberg's Archives of Pharmacology.

Binding of Ligands to GPCRs – How Valid is a Thermodynamic Discrimination of Antagonists and Agonists?

Andrea Strasser, Hans Joachim Wittmann, Hans-Joachim Wittmann, 2012 .

The First Photochromic Affinity Switch for the Human Cannabinoid Receptor 2

Dominik Dolles, Hans-Joachim Wittmann, A. Strasser, 2018 .

Structure-Activity Relationships and Computational Investigations into the Development of Potent and Balanced Dual-Acting Butyrylcholinesterase Inhibitors and Human Cannabinoid Receptor 2 Ligands with Pro-Cognitive in Vivo Profiles.

Dominik Dolles, Hans-Joachim Wittmann, A. Strasser, 2018, Journal of medicinal chemistry.

Molecular Modelling Approaches for the Analysis of Histamine Receptors and Their Interaction with Ligands.

Hans-Joachim Wittmann, A. Strasser, 2017, Handbook of experimental pharmacology.

New insights into the cross-linking and degradation mechanism of Diels-Alder hydrogels.

Hans-Joachim Wittmann, A. Strasser, A. Goepferich, 2015, Journal of materials chemistry. B.

Molecular modeling studies give hint for the existence of a symmetric hβ2R-Gαβγ-homodimer

Hans-Joachim Wittmann, A. Strasser, 2013, Journal of Molecular Modeling.

Conformational Restriction and Enantioseparation Increase Potency and Selectivity of Cyanoguanidine-Type Histamine H4 Receptor Agonists.

Hans-Joachim Wittmann, A. Strasser, A. Buschauer, 2016, Journal of medicinal chemistry.

Synthesis and Structure−Activity Relationships of Cyanoguanidine-Type and Structurally Related Histamine H4 Receptor Agonists§

A. Strasser, R. Seifert, Patrick Igel, 2009 .

Modulation of GPCRs by monovalent cations and anions

Hans-Joachim Wittmann, A. Strasser, R. Seifert, 2014, Naunyn-Schmiedeberg's Archives of Pharmacology.

Molecular and cellular analysis of human histamine receptor subtypes.

A. Strasser, R. Seifert, A. Buschauer, 2013, Trends in pharmacological sciences.

Nα-Methylated phenylhistamines exhibit affinity to the hH4R—a pharmacological and molecular modelling study

Hans-Joachim Wittmann, A. Strasser, R. Seifert, 2011, Naunyn-Schmiedeberg's Archives of Pharmacology.

Interactions of Histamine H1-Receptor Agonists and Antagonists with the Human Histamine H4-Receptor

A. Strasser, R. Seifert, D. Neumann, 2009, Molecular Pharmacology.

Binding pathway of histamine to the hH4R, observed by unconstrained molecular dynamics.

Andrea Strasser, Hans-Joachim Wittmann, Hans-Joachim Wittmann, 2015, Bioorganic & medicinal chemistry letters.

Pharmacological profile of astemizole-derived compounds at the histamine H1 and H4 receptor—H1/H4 receptor selectivity

Hans-Joachim Wittmann, A. Strasser, S. Elz, 2013, Naunyn-Schmiedeberg's Archives of Pharmacology.

Molecular Basis for the Selective Interaction of Synthetic Agonists with the Human Histamine H1-Receptor Compared with the Guinea Pig H1-Receptor

Hans-Joachim Wittmann, A. Strasser, R. Seifert, 2009, Molecular Pharmacology.

Ligand-Specific Contribution of the N Terminus and E2-Loop to Pharmacological Properties of the Histamine H1-Receptor

Hans-Joachim Wittmann, A. Strasser, R. Seifert, 2008, Journal of Pharmacology and Experimental Therapeutics.