Kristin L. Andrews

发表

Discovery of potent, selective, and metabolically stable 4-(pyridin-3-yl)cinnolines as novel phosphodiesterase 10A (PDE10A) inhibitors.

E. Hu, R. Kunz, Shannon Rumfelt, 2012, Bioorganic & medicinal chemistry letters.

Discovery of imidazopyridazines as potent Pim-1/2 kinase inhibitors.

Kristin L. Andrews, B. Herberich, Matthew R. Lee, 2016, Bioorganic & medicinal chemistry letters.

The discovery and optimization of aminooxadiazoles as potent Pim kinase inhibitors.

Kristin L. Andrews, B. Herberich, Matthew R. Lee, 2015, Bioorganic & medicinal chemistry letters.

Discovery and Structure-Guided Optimization of Diarylmethanesulfonamide Disrupters of Glucokinase-Glucokinase Regulatory Protein (GK-GKRP) Binding: Strategic Use of a N → S (nN → σ*S-X) Interaction for Conformational Constraint.

Kristin L. Andrews, Jiandong Zhang, S. Chmait, 2015, Journal of medicinal chemistry.

Pharmacological characterization of potent and selective NaV1.7 inhibitors engineered from Chilobrachys jingzhao tarantula venom peptide JzTx-V

J. B. Jordan, Kristin L. Andrews, R. Stöcklin, 2018, PloS one.

Engineering potent and selective analogues of GpTx-1, a tarantula venom peptide antagonist of the Na(V)1.7 sodium channel.

L. Poppe, Kristin L. Andrews, R. Stöcklin, 2015, Journal of Medicinal Chemistry.

Oxopyrido[2,3-d]pyrimidines as Covalent L858R/T790M Mutant Selective Epidermal Growth Factor Receptor (EGFR) Inhibitors.

E. Lobenhofer, Kristin L. Andrews, B. Herberich, 2015, ACS medicinal chemistry letters.

Sustained inhibition of the NaV1.7 sodium channel by engineered dimers of the domain II binding peptide GpTx-1.

L. Poppe, Kristin L. Andrews, S. Meng, 2015, Bioorganic & medicinal chemistry letters.

Engineering NaV1.7 Inhibitory JzTx-V Peptides with a Potency and Basicity Profile Suitable for Antibody Conjugation To Enhance Pharmacokinetics.

Kristin L. Andrews, B. Herberich, B. Moyer, 2019, ACS chemical biology.

Discovery of 1H-pyrazol-3(2H)-ones as potent and selective inhibitors of protein kinase R-like endoplasmic reticulum kinase (PERK).

Kristin L. Andrews, D. Powers, R. Kendall, 2015, Journal of medicinal chemistry.

1,2,4-Triazolsulfone: A novel isosteric replacement of acylsulfonamides in the context of NaV1.7 inhibition.

Kristin L. Andrews, R. Fremeau, M. Chu-Moyer, 2018, Bioorganic & medicinal chemistry letters.

Discovery of Tarantula Venom-Derived NaV1.7-Inhibitory JzTx-V Peptide 5-Br-Trp24 Analogue AM-6120 with Systemic Block of Histamine-Induced Pruritis.

Dong Liu, Kristin L. Andrews, Zhulun Wang, 2018, Journal of medicinal chemistry.