S. Brewerton

发表

Extensions to In Silico Bioactivity Predictions Using Pathway Annotations and Differential Pharmacology Analysis: Application to Xenopus laevis Phenotypic Readouts

A. Bender, S. Liggi, Georgios Drakakis, 2013, Molecular informatics.

Extending in silico mechanism-of-action analysis by annotating targets with pathways: application to cellular cytotoxicity readouts.

R. Glen, A. Bender, S. Liggi, 2014, Future medicinal chemistry.

Identification of individuals by trait prediction using whole-genome sequencing data

Eun Yong Kang, Smriti R. Ramakrishnan, Seunghak Lee, 2017, Proceedings of the National Academy of Sciences.

Connecting gene expression data from connectivity map and in silico target predictions for small molecule mechanism-of-action analysis.

Aakash Chavan Ravindranath, A. Bender, S. Liggi, 2015, Molecular bioSystems.

Diverse, high-quality test set for the validation of protein-ligand docking performance.

Paul N. Mortenson, C. Murray, M. Verdonk, 2007, Journal of medicinal chemistry.

Deep Sequencing of 10,000 Human Genomes

Levi C. T. Pierce, E. Kirkness, N. Shah, 2016, bioRxiv.

Fast and accurate HLA typing from short-read next-generation sequence data with xHLA

E. Kirkness, J. Venter, J. Venter, 2017, Proceedings of the National Academy of Sciences.

Comparative mode-of-action analysis following manual and automated phenotype detection in Xenopus laevis

A. Bender, Georgios Drakakis, Adam E. Hendry, 2014 .

Autonomous folding of interdomain regions of a modular polyketide synthase

S. Brewerton, R. N. Miguel, R. Broadhurst, 2007, The FEBS journal.

Structural analysis of DNA-PKcs: modelling of the repeat units and insights into the detailed molecular architecture.

T. Blundell, S. Brewerton, A. Doré, 2004, Journal of structural biology.

Correction

Eun Yong Kang, Smriti R. Ramakrishnan, Seunghak Lee, 1975, Nature.

Polypharmacological in Silico Bioactivity Profiling and Experimental Validation Uncovers Sedative-Hypnotic Effects of Approved and Experimental Drugs in Rat.

Andreas Bender, Georgios Drakakis, Suzanne C Brewerton, 2017, ACS chemical biology.

Whole-genome sequencing identifies common-to-rare variants associated with human blood metabolites

Amalio Telenti, C Thomas Caskey, Nicholas J Schork, 2017, Nature Genetics.

The use of protein-ligand interaction fingerprints in docking.

Suzanne C Brewerton, S. Brewerton, 2008, Current opinion in drug discovery & development.

Deep sequencing of 10,000 human genomes

Levi C. T. Pierce, Ahmed Moustafa, Amalio Telenti, 2016, Proceedings of the National Academy of Sciences.

Precision medicine screening using whole-genome sequencing and advanced imaging to identify disease risk in adults

Anders M. Dale, James B. Brewer, Victor Lavrenko, 2017, Proceedings of the National Academy of Sciences.

Correction

Eun Yong Kang, Smriti R. Ramakrishnan, Seunghak Lee, 2021, Journal of the history of the neurosciences.

Correction

Eun Yong Kang, Smriti R. Ramakrishnan, Seunghak Lee, 2020, The Clinical neuropsychologist.

Identification of DNA-PK in the arthropods. Evidence for the ancient ancestry of vertebrate non-homologous end-joining.

T. Blundell, S. Brewerton, A. Drake, 2004, DNA repair.

The conserved N-terminal region of the mitotic checkpoint protein BUBR1: a putative TPR motif of high surface activity.

T. Blundell, S. Brewerton, A. Venkitaraman, 2005, Biophysical journal.

Structural biology and bioinformatics in drug design: opportunities and challenges for target identification and lead discovery

Catherine L. Worth, B. L. Sibanda, T. Blundell, 2006, Philosophical Transactions of the Royal Society B: Biological Sciences.

An Unbiased Approach to Identifying Tau Kinases That Phosphorylate Tau at Sites Associated with Alzheimer Disease

S. Brewerton, P. Davies, P. Szekeres, 2013, The Journal of Biological Chemistry.

An unbiased approach to identifying tau kinases that phosphorylate tau at sites associated with early Alzheimer's disease

S. Brewerton, P. Davies, M. Poidinger, 2012, Alzheimer's & Dementia.

Whole-genome sequencing identifies common-to-rare variants associated with human blood metabolites

E. Kirkness, J. Venter, N. Schork, 2017, Nature Genetics.

ChEMBLSpace - a graphical explorer of the chemogenomic space covered by the ChEMBL database

George Papadatos, David A. Evans, David A. Thorner, 2013, Bioinform..

Extending in silico mechanism-of-action analysis by annotating targets with pathways: application to cellular cytotoxicity readouts.

R. Glen, A. Bender, Alexios Koutsoukas, 2014, Future medicinal chemistry.

Extensions to In Silico Bioactivity Predictions Using Pathway Annotations and Differential Pharmacology Analysis: Application to Xenopus laevis Phenotypic Readouts

A. Bender, Georgios Drakakis, Adam E. Hendry, 2013, Molecular informatics.

Connecting gene expression data from connectivity map and in silico target predictions for small molecule mechanism-of-action analysis.

Hinrich W. H. Göhlmann, Aakash Chavan Ravindranath, A. Bender, 2015, Molecular bioSystems.

Detecting affiliation in colaughter across 24 societies

Eun Yong Kang, Smriti R. Ramakrishnan, Seunghak Lee, 2016 .

No major flaws in “Identification of individuals by trait prediction using whole-genome sequencing data”

Eun Yong Kang, Smriti R. Ramakrishnan, Seunghak Lee, 2017, bioRxiv.