C. Müller

G. V. van Westen, A. IJzerman, C. Müller, 2011, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Chemistry of porphyrins in fossil plants and animals

C. Müller, P. M. Sander, C. Gee, 2021, RSC advances.

CD39/ENTPD1 expression by CD4+Foxp3+ regulatory T cells promotes hepatic metastatic tumor growth in mice.

Takashi Murakami, C. Müller, Wenda Gao, 2010, Gastroenterology.

Decoding Signaling and Function of the Orphan G Protein–Coupled Receptor GPR17 with a Small-Molecule Agonist

Daniel Schulz, Evi Kostenis, Michel Gillard, 2013, Science Signaling.

Identification by Site-directed Mutagenesis of Residues Involved in Ligand Recognition and Activation of the Human A3 Adenosine Receptor*

K. Jacobson, C. Müller, Zhang-Guo Gao, 2002, The Journal of Biological Chemistry.

Flavonoids — novel lead compounds for the development of P2Y2 receptor antagonists

C. Müller, Marko Kaulich, Franziska Streicher, 2003 .

Allosteric modulation of A(3) adenosine receptors by a series of 3-(2-pyridinyl)isoquinoline derivatives.

K. Jacobson, A. IJzerman, C. Müller, 2001, Molecular pharmacology.

[3H]8-Ethyl-4-methyl-2-phenyl-(8R)-4,5,7,8-tetrahydro-1h-imidazo[2,1-i]-purin-5- one ([3H]PSB-11), a novel high-affinity antagonist radioligand for human A3 adenosine receptors

Christa E. Müller, C. Müller, Mark Thorand, 2002 .

Adenosine A2A receptor agonists with potent antiplatelet activity

Julio Caballero, C. Müller, I. Palomo, 2018, Platelets.

Adenosine A2A receptor blockade reverts hippocampal stress-induced deficits and restores corticosterone circadian oscillation

J. Changeux, B. Lambolez, B. Gutkin, 2013, Molecular Psychiatry.

Blocking striatal adenosine A2A receptors: a new strategy for basal ganglia disorders.

C. Müller, S. Ferré, 2007, Recent patents on CNS drug discovery.

α,β-Methylene-ADP (AOPCP) Derivatives and Analogues: Development of Potent and Selective ecto-5'-Nucleotidase (CD73) Inhibitors.

C. Müller, N. Sträter, J. Pippel, 2015, Journal of medicinal chemistry.

Cell‐permeable high‐affinity tracers for Gq proteins provide structural insights, reveal distinct binding kinetics and identify small molecule inhibitors

C. Müller, B. Fleischmann, M. Gütschow, 2019, British journal of pharmacology.

Prodrug Approaches for Enhancing the Bioavailability of Drugs with Low Solubility

C. Müller, C. Müller, 2009, Chemistry & biodiversity.

7-Alkyl-3-benzylcoumarins: a versatile scaffold for the development of potent and selective cannabinoid receptor agonists and antagonists.

T. Karcz, C. Müller, W. Wenzel, 2012, Journal of medicinal chemistry.

Arylidene imidazothiazoles. Synthesis, structure and benzodiazepine receptor binding

J. Karolak-Wojciechowska, C. Müller, K. Kieć‐Kononowicz, 1999 .

CD39/Ectonucleoside Triphosphate Diphosphohydrolase 1 Provides Myocardial Protection During Cardiac Ischemia/Reperfusion Injury

C. Müller, S. Robson, T. Eckle, 2007, Circulation.

CD 39 / Ectonucleoside Triphosphate Diphosphohydrolase 1 Provides Myocardial Protection During Cardiac Ischemia / Reperfusion Injury

C. Müller, S. Robson, T. Eckle, 2007 .

Contribution of E‐NTPDasel (CD39) to renal protection from ischemia‐reperfusion injury

C. Müller, K. Klingel, D. Huang, 2007, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Cloning and Functional Expression of a Novel Gi Protein-Coupled Receptor for Adenine from Mouse Brain

A. Schiedel, C. Müller, I. von Kügelgen, 2008, Molecular Pharmacology.

P2Y2 receptor modulates shear stress-induced cell alignment and actin stress fibers in human umbilical vein endothelial cells

B. Olde, C. Müller, D. Erlinge, 2016, Cellular and Molecular Life Sciences.

Shear stress modulates endothelial KLF2 through activation of P2X4

B. Olde, C. Müller, D. Erlinge, 2015, Purinergic Signalling.

Discovery of Tricyclic Xanthines as Agonists of the Cannabinoid-Activated Orphan G-Protein-Coupled Receptor GPR18.

A. Drabczyńska, C. Müller, K. Kieć‐Kononowicz, 2020, ACS medicinal chemistry letters.

Molecular and functional interaction between GPR18 and cannabinoid CB2 G‐protein‐coupled receptors. Relevance in neurodegenerative diseases

C. Müller, K. Kieć‐Kononowicz, R. Franco, 2018, Biochemical pharmacology.

Adenosine A2A receptor ligand recognition and signaling is blocked by A2B receptors

K. Fuxe, D. Borroto-Escuela, A. Schiedel, 2018, Oncotarget.

Caffeine analogs: structure-activity relationships at adenosine receptors.

C. Müller, J. Daly, I. Hide, 1991, Pharmacology.

Farnesyl pyrophosphate is an endogenous antagonist to ADP-stimulated P2Y12 receptor-mediated platelet aggregation

B. Olde, K. Jacobson, C. Müller, 2012, Thrombosis and Haemostasis.

Tools and drugs for uracil nucleotide‐activated P2Y receptors

C. Müller, Muhammad Rafehi, 2018, Pharmacology & therapeutics.

High-sensitivity capillary electrophoresis method for monitoring purine nucleoside phosphorylase and adenosine deaminase reactions by a reversed electrode polarity switching mode.

C. Müller, J. Iqbal, 2011, Journal of chromatography. A.

Indazole- and indole-5-carboxamides: selective and reversible monoamine oxidase B inhibitors with subnanomolar potency.

C. Müller, N. Tzvetkov, Sonja Hinz, 2014, Journal of medicinal chemistry.

Preyssler-Pope-Jeannin Polyanions [NaP5 W30 O110 ]14- and [AgP5 W30 O110 ]14- : Microwave-Assisted Synthesis, Structure, and Biological Activity

C. Müller, U. Kortz, A. Mougharbel, 2018, Zeitschrift für anorganische und allgemeine Chemie.

Genome Editing in Neuroepithelial Stem Cells to Generate Human Neurons with High Adenosine‐Releasing Capacity

C. Müller, David E. Paschon, P. Gregory, 2018, Stem cells translational medicine.

The 2016 Frontiers in Medicinal Chemistry Conference in Bonn

C. Müller, K. Baringhaus, D. Thimm, 2017, ChemMedChem.

A2A and A2B adenosine receptors: the extracellular loop 2 determines high (A2A) or low affinity (A2B) for adenosine.

S. Moro, A. Schiedel, C. Müller, 2019, Biochemical pharmacology.

Domains for activation and inactivation in G protein-coupled receptors--a mutational analysis of constitutive activity of the adenosine A2B receptor.

G. V. van Westen, A. IJzerman, C. Müller, 2014, Biochemical pharmacology.

Adenosine receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database

B. Fredholm, K. Klotz, K. Jacobson, 2019, IUPHAR/BPS Guide to Pharmacology CITE.

The map kinase ERK regulates renal activity of cyclin-dependent kinase 2 in experimental glomerulonephritis.

P. Boor, C. Müller, J. Floege, 2007, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

Nanodiscs for INPHARMA NMR Characterization of GPCRs: Ligand Binding to the Human A2A Adenosine Receptor.

C. Müller, C. Griesinger, T. Exner, 2017, Angewandte Chemie.

Development of high-affinity fluorinated ligands for cannabinoid subtype 2 receptor, and in vitro evaluation of a radioactive tracer for imaging.

C. Müller, J. Bucerius, D. Stalke, 2022, European journal of medicinal chemistry.

Coordination of capsule assembly and cell wall biosynthesis in Staphylococcus aureus

C. Müller, H. Sahl, M. Sylvester, 2019, Nature Communications.

Synthesis of Novel Fluorinated Xanthine Derivatives with High Adenosine A2B Receptor Binding Affinity

C. Müller, J. Steinbach, P. Brust, 2021, Pharmaceuticals.

Development of a Radiofluorinated Adenosine A2B Receptor Antagonist as Potential Ligand for PET Imaging

C. Müller, J. Steinbach, P. Brust, 2020, International journal of molecular sciences.

Synthesis and Analgesic Activity of Annelated Xanthine Derivatives in Experimental Models in Rodents

A. Drabczyńska, Meryem Köse, T. Karcz, 2015, Archiv der Pharmazie.

Interaction of valerian extracts of different polarity with adenosine receptors: identification of isovaltrate as an inverse agonist at A1 receptors.

C. Müller, K. Nieber, R. Mayer, 2007, Biochemical pharmacology.

[3H]Adenine is a suitable radioligand for the labeling of G protein-coupled adenine receptors but shows high affinity to bacterial contaminations in buffer solutions

A. Schiedel, C. Müller, Bernt B. A. Alsdorf, 2007, Purinergic Signalling.

Development of off‐line and on‐line capillary electrophoresis methods for the screening and characterization of adenosine kinase inhibitors and substrates

C. Müller, J. Iqbal, C. Müller, 2006, Electrophoresis.

Synthesis and structure-activity relationships of 3,7-dimethyl-1-propargylxanthine derivatives, A2A-selective adenosine receptor antagonists.

C. Müller, M. Pawłowski, J. Sandoval-Ramírez, 1997, Journal of medicinal chemistry.

Chronic A2A antagonist treatment alleviates parkinsonian locomotor deficiency in MitoPark mice

K. Fuxe, D. Marcellino, C. Müller, 2010, Neurobiology of Disease.

Lack of adenosine A1 and dopamine D2 receptor-mediated modulation of the cardiovascular effects of the adenosine A2A receptor agonist CGS 21680.

C. Müller, E. Thorndike, S. Goldberg, 2004, European journal of pharmacology.

3CL Protease Inhibitors with an Electrophilic Arylketone Moiety as Anti-SARS-CoV-2 Agents.

C. Müller, M. Gütschow, A. Kawaguchi, 2021, Journal of medicinal chemistry.

GPR18-Mediated Relaxation of Human Isolated Pulmonary Arteries

C. Müller, K. Kieć‐Kononowicz, B. Malinowska, 2022, International journal of molecular sciences.

N-substituted phenoxazine and acridone derivatives: structure-activity relationships of potent P2X4 receptor antagonists.

C. Müller, A. El-Tayeb, Aliaa Abdelrahman, 2012, Journal of medicinal chemistry.

Convergent Synthesis of the Potent P2Y Receptor Antagonist MG 50-3-1 Based on a Regioselective Ullmann Coupling Reaction

C. Müller, Y. Baqi, Younis Baqi, 2012, Molecules.

The platelet P2Y12 receptor under normal and pathological conditions. Assessment with the radiolabeled selective antagonist [3H]PSB-0413

C. Müller, C. Gachet, P. Ohlmann, 2013, Purinergic Signalling.

Selective nucleoside triphosphate diphosphohydrolase-2 (NTPDase2) inhibitors: nucleotide mimetics derived from uridine-5'-carboxamide.

C. Müller, J. Sévigny, M. Munkonda, 2008, Journal of medicinal chemistry.

Structure-activity relationships of anthraquinone derivatives derived from bromaminic acid as inhibitors of ectonucleoside triphosphate diphosphohydrolases (E-NTPDases)

C. Müller, Y. Baqi, J. Iqbal, 2008, Purinergic Signalling.

7-Deaza-2-phenyladenines: structure-activity relationships of potent A1 selective adenosine receptor antagonists.

K. Rothenhäusler, C. Müller, J. Daly, 1990, Journal of medicinal chemistry.

Synthesis of BODIPY Derivatives Substituted with Various Bioconjugatable Linker Groups: A Construction Kit for Fluorescent Labeling of Receptor Ligands

C. Müller, J. Iqbal, A. El-Tayeb, 2013, Journal of Fluorescence.

Adenosine A2A Receptor Antagonists in Drug Development

C. Müller, 2015 .

Helmholtz-Zentrum Dresden-Rossendorf (HZDR) Expression of ecto-nucleoside triphosphate diphosphohydrolases-2 and -3 by the enteric nervous system impacts inflammation in experimental colitis and Crohn’s disease

C. Müller, S. Robson, E. Csizmadia, 2020 .

Expression of Ecto-nucleoside Triphosphate Diphosphohydrolases-2 and -3 in the Enteric Nervous System Affects Inflammation in Experimental Colitis and Crohn’s Disease

C. Müller, J. Sévigny, S. Robson, 2017, Journal of Crohn's & colitis.

Targeting renal purinergic signalling for the treatment of lithium‐induced nephrogenic diabetes insipidus

C. Müller, D. Kohan, B. Kishore, 2015, Acta physiologica.

Adenosine activates brown adipose tissue and recruits beige adipocytes via A2A receptors

C. Müller, P. Brust, S. Enerbäck, 2014, Nature.

Modulation of insulin release by adenosine A1 receptor agonists and antagonists in INS‐1 cells: The possible contribution of 86Rb+ efflux and 45Ca2+ uptake

C. Müller, J. Knittel, E. Verspohl, 2008, Cell biochemistry and function.

A1 adenosine receptors and their ligands: overview and recent developments.

C. Müller, 2001, Farmaco.

Hippocampal synaptic dysfunction in the SOD1G93A mouse model of Amyotrophic Lateral Sclerosis: Reversal by adenosine A2AR blockade

C. Müller, Y. Baqi, D. Rombo, 2020, Neuropharmacology.

A2A adenosine receptor deletion is protective in a mouse model of Tauopathy

R. D'Hooge, L. Buée, C. Müller, 2016, Molecular Psychiatry.

Motor effects induced by a blockade of adenosine A2A receptors in the caudate‐putamen

W. Hauber, C. Müller, J. Nagel, 1998, Neuroreport.

Modulating P1 Adenosine Receptors in Disease Progression of SOD1G93A Mutant Mice

C. Müller, Y. Baqi, P. Popoli, 2019, Neurochemical Research.

A2A adenosine receptor deletion is protective in a mouse model of Tauopathy

R. D'Hooge, L. Buée, C. Müller, 2016, Molecular Psychiatry.

P2Y receptors in GtoPdb v.2021.3

G. Burnstock, K. Jacobson, C. Müller, 2021, IUPHAR/BPS Guide to Pharmacology CITE.

PSB 603 - a known selective adenosine A2B receptor antagonist - has anti-inflammatory activity in mice.

C. Müller, K. Kieć‐Kononowicz, M. Bednarski, 2020, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Sulfated Polysaccharides from Macroalgae Are Potent Dual Inhibitors of Human ATP-Hydrolyzing Ectonucleotidases NPP1 and CD39

C. Müller, J. Sévigny, J. Pelletier, 2021, Marine drugs.

7-Deazaadenines bearing polar substituents: structure-activity relationships of new A(1) and A(3) adenosine receptor antagonists.

K. Klotz, C. Müller, K. Eger, 2000, Journal of medicinal chemistry.

Targeted inhibition of Gq signaling induces airway relaxation in mouse models of asthma

I. Hall, C. Müller, B. Fleischmann, 2017, Science Translational Medicine.

Nucleotide P2Y1 receptor agonists are in vitro and in vivo prodrugs of A1/A3 adenosine receptor agonists: implications for roles of P2Y1 and A1/A3 receptors in physiology and pathology

K. Jacobson, C. Müller, Zhang-Guo Gao, 2020, Purinergic Signalling.

Extracellular adenosine reversibly inhibits the activation of human regulatory T cells and negatively influences the achievement of the operational tolerance in liver transplantation

C. Müller, J. Herrero, L. Martínez-Alarcón, 2018, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

Synthesis of Novel Potent Archazolids: Pharmacology of an Emerging Class of Anticancer Drugs.

Meryem Köse, C. Müller, M. Gütschow, 2020, Journal of medicinal chemistry.

Development and validation of a capillary electrophoresis method for the characterization of herpes simplex virus type 1 (HSV-1) thymidine kinase substrates and inhibitors.

C. Müller, G. Folkers, L. Scapozza, 2007, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Update of P2Y receptor pharmacology: IUPHAR Review 27

T. Schöneberg, K. Jacobson, C. Müller, 2020, British journal of pharmacology.

Ammonium-induced calcium mobilization in 1321N1 astrocytoma cells.

Meryem Köse, C. Müller, Petra Hillmann, 2008, Toxicology and applied pharmacology.

Cardiac myocyte-secreted cAMP exerts paracrine action via adenosine receptor activation.

C. Müller, J. Hulot, T. Thum, 2014, The Journal of clinical investigation.

Nucleoside-5'-monophosphates as prodrugs of adenosine A2A receptor agonists activated by ecto-5'-nucleotidase.

C. Müller, J. Schrader, Marion Schneider, 2009, Journal of medicinal chemistry.

A Cellular Assay for the Identification and Characterization of Connexin Gap Junction Modulators

A. Schiedel, C. Müller, C. Steinhäuser, 2021, International journal of molecular sciences.

Agonists and Antagonists for Purinergic Receptors.

C. Müller, Y. Baqi, V. Namasivayam, 2020, Methods in molecular biology.

Fluorescent-Labeled Selective Adenosine A2B Receptor Antagonist Enables Competition Binding Assay by Flow Cytometry.

Meryem Köse, T. Karcz, C. Müller, 2018, Journal of medicinal chemistry.

P2Y1‐like nucleotide receptors—Structures, molecular modeling, mutagenesis, and oligomerization

C. Müller, Alexander Neumann, V. Namasivayam, 2020 .

Erratum: A2A adenosine receptor deletion is protective in a mouse model of Tauopathy (Molecular Psychiatry (2016) 21 149 (doi:10.1038/mp.2015.115))

R. D'Hooge, L. Buée, C. Müller, 2016 .

Large‐volume sample stacking with polarity switching for monitoring of nucleotide pyrophosphatase/phosphodiesterase 1 (NPP1) reactions by capillary electrophoresis

C. Müller, Sang-Yong Lee, C. Müller, 2014, Electrophoresis.

A highly sensitive capillary electrophoresis method using p-nitrophenyl 5'-thymidine monophosphate as a substrate for the monitoring of nucleotide pyrophosphatase/phosphodiesterase activities.

C. Müller, J. Sévigny, S. Lévesque, 2012, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Medicinal chemistry of P2 and adenosine receptors: Common scaffolds adapted for multiple targets.

K. Jacobson, A. IJzerman, C. Müller, 2020, Biochemical pharmacology.

[Progress in cannabis research from a pharmaceutical chemist's point of view].

C. Müller, 2019, Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz.

Pharmacological evaluation of new constituents of “Spice”: synthetic cannabinoids based on indole, indazole, benzimidazole and carbazole scaffolds

C. Müller, J. Meiler, B. Madea, 2018, Forensic Toxicology.

Understanding the Role of Adenosine A2AR Heteroreceptor Complexes in Neurodegeneration and Neuroinflammation

K. Fuxe, D. Borroto-Escuela, C. Müller, 2018, Front. Neurosci..

Fast, efficient capillary electrophoresis method for measuring nucleotide degradation and metabolism.

C. Müller, Marko Kaulich, Ramatullah Qurishi, 2002, Journal of chromatography. A.

Interactions of valerian extracts and a fixed valerian-hop extract combination with adenosine receptors.

C. Müller, E. Abourashed, U. Koetter, 2002, Life sciences.

Mechanism underlying the contractile activity of UTP in the mammalian heart

C. Müller, A. Simm, H. Treede, 2018, European journal of pharmacology.

Basic Chemistry of 2-Nitroimidazoles (Azomycin Derivatives)

C. Müller, 1999 .

Mass spectrometric identification of modified urinary nucleosides used as potential biomedical markers by LC–ITMS coupling

C. Müller, S. Laufer, H. Liebich, 2005, Analytical and bioanalytical chemistry.

Discovery of Tricyclic Xanthines as Agonists of the Cannabinoid-Activated Orphan G-Protein-Coupled Receptor GPR18.

A. Drabczyńska, C. Müller, K. Kieć‐Kononowicz, 2020, ACS medicinal chemistry letters.

Structural modifications of UMP, UDP, and UTP leading to subtype-selective agonists for P2Y2, P2Y4, and P2Y6 receptors.

C. Müller, R. Nicholas, A. El-Tayeb, 2011, Journal of medicinal chemistry.

Synthesis and preliminary evaluation of [3H]PSB-0413, a selective antagonist radioligand for platelet P2Y12 receptors.

C. Müller, A. El-Tayeb, Kerstin J Griessmeier, 2005, Bioorganic & medicinal chemistry letters.

1,8-disubstituted xanthine derivatives: synthesis of potent A2B-selective adenosine receptor antagonists.

C. Müller, J. Daly, J. Sandoval-Ramírez, 2002, Journal of medicinal chemistry.

Heterologous Expression, Biosynthetic Studies, and Ecological Function of the Selective Gq-Signaling Inhibitor FR900359.

C. Müller, H. Schiöth, E. Kostenis, 2018, Angewandte Chemie.

Crystal structure of the human ecto-5'-nucleotidase (CD73): insights into the regulation of purinergic signaling.

C. Müller, N. Sträter, J. Pippel, 2012, Structure.

Design, synthesis and biological evaluation of suramin-derived dual antagonists of the proinflammatory G protein-coupled receptors P2Y2 and GPR17.

C. Müller, Thanigaimalai Pillaiyar, Aliaa Abdelrahman, 2019, European journal of medicinal chemistry.

Development of Chromen-4-one Derivatives as (Ant)agonists for the Lipid-Activated G Protein-Coupled Receptor GPR55 with Tunable Efficacy

C. Müller, T. Blaschke, Clara T. Schoeder, 2019, ACS Omega.

Structure-activity relationships of imidazothiazinones and analogs as antagonists of the cannabinoid-activated orphan G protein-coupled receptor GPR18.

C. Müller, K. Kieć‐Kononowicz, Agnieszka Olejarz-Maciej, 2018, European journal of medicinal chemistry.

Pharmacological evaluation of synthetic cannabinoids identified as constituents of spice

C. Müller, B. Madea, C. Hess, 2016, Forensic Toxicology.

P2Y2 Receptor Promotes High-Fat Diet-Induced Obesity

C. Müller, B. Kishore, C. Ecelbarger, 2020, Frontiers in Endocrinology.

Fluorescent Probes for Ecto-5'-nucleotidase (CD73).

C. Müller, G. Yegutkin, I. Schmidt-Wolf, 2020, ACS medicinal chemistry letters.

Synthesis and structure-activity relationships of cerebroside analogues as substrates of cerebroside sulphotransferase and discovery of a competitive inhibitor

C. Müller, S. van Calenbergh, V. Gieselmann, 2020, Journal of enzyme inhibition and medicinal chemistry.

X‐Ray Co‐Crystal Structure Guides the Way to Subnanomolar Competitive Ecto‐5′‐Nucleotidase (CD73) Inhibitors for Cancer Immunotherapy

C. Müller, N. Sträter, J. Pippel, 2019, Advanced Therapeutics.

Structural characterization and pharmacological evaluation of the new synthetic cannabinoid CUMYL-PEGACLONE.

C. Müller, C. Hess, V. Angerer, 2018, Drug testing and analysis.

Polyoxometalates--potent and selective ecto-nucleotidase inhibitors.

C. Müller, J. Sévigny, K. Brylev, 2015, Biochemical pharmacology.

Fluorescence polarization immunoassays for monitoring nucleoside triphosphate diphosphohydrolase (NTPDase) activity.

C. Müller, J. Sévigny, J. Lecka, 2015, The Analyst.

Imidazopyridine- and purine-thioacetamide derivatives: potent inhibitors of nucleotide pyrophosphatase/phosphodiesterase 1 (NPP1).

C. Müller, P. Herdewijn, J. Rozenski, 2014, Journal of medicinal chemistry.

A highly sensitive CE‐UV method with dynamic coating of silica‐fused capillaries for monitoring of nucleotide pyrophosphatase/phosphodiesterase reactions

C. Müller, J. Sévigny, S. Lévesque, 2008, Electrophoresis.

8-(Sulfostyryl)xanthines: water-soluble A2A-selective adenosine receptor antagonists.

K. Klotz, C. Müller, J. Sandoval-Ramírez, 1998, Bioorganic & medicinal chemistry.

Configurationally stable analogs of styrylxanthines as A2A adenosine receptor antagonist

C. Müller, M. Pawłowski, U. Geis, 1997 .

Aza‐Analogs of 8‐Styrylxanthines as A2A‐Adenosine Receptor Antagonists

C. Müller, M. Pawłowski, P. Talik, 1997, Archiv der Pharmazie.

Synthesis and structure-activity relationships of quinolinone and quinoline-based P2X7 receptor antagonists and their anti-sphere formation activities in glioblastoma cells.

W. Goddard, Ji‐Hyun Lee, C. Müller, 2018, European journal of medicinal chemistry.

Structure-activity relationships at human and rat A2B adenosine receptors of xanthine derivatives substituted at the 1-, 3-, 7-, and 8-positions.

K. Jacobson, C. Müller, J. Linden, 2002, Journal of medicinal chemistry.

The Natural Product Magnolol as a Lead Structure for the Development of Potent Cannabinoid Receptor Agonists

C. Müller, V. Rempel, A. Fuchs, 2013, PloS one.

Sphingosine-1-phosphate induces migration of microglial cells via activation of volume-sensitive anion channels, ATP secretion and activation of purinergic receptors.

C. Müller, F. Markwardt, C. Grossmann, 2020, Biochimica et biophysica acta. Molecular cell research.

Development of potent and selective inhibitors of ecto-5'-nucleotidase based on an anthraquinone scaffold.

J. Bajorath, C. Müller, Peter Ripphausen, 2010, Journal of medicinal chemistry.

Extracellular NAD(+) induces a rise in [Ca(2+)](i) in activated human monocytes via engagement of P2Y(1) and P2Y(11) receptors.

C. Müller, S. Hauschildt, Carina Klein, 2009, Cell calcium.

Recombinant expression of ecto-nucleotide pyrophosphatase/phosphodiesterase 4 (NPP4) and development of a luminescence-based assay to identify inhibitors.

C. Müller, H. Stephan, Sang-Yong Lee, 2020, Analytical biochemistry.

Clopidogrel attenuates lithium-induced alterations in renal water and sodium channels/transporters in mice

C. Müller, B. Kishore, C. Ecelbarger, 2015, Purinergic Signalling.

P2Y12 Receptor Localizes in the Renal Collecting Duct and Its Blockade Augments Arginine Vasopressin Action and Alleviates Nephrogenic Diabetes Insipidus.

C. Müller, D. Kohan, B. Kishore, 2015, Journal of the American Society of Nephrology : JASN.

Irreversible Antagonists for the Adenosine A2B Receptor

C. Müller, Jonathan G. Schlegel, J. Voss, 2022, Molecules.

Central P2Y12 receptor blockade alleviates inflammatory and neuropathic pain and cytokine production in rodents

B. Sperlágh, C. Müller, M. Baranyi, 2014, Neurobiology of Disease.

pain and cytokine production in rodents

B. Sperlágh, C. Müller, M. Baranyi, 2014 .

Evidence for the Functional Expression and Pharmacological Characterization of Adenine Receptors in Native Cells and Tissues

C. Müller, G. Cristalli, S. Vittori, 2005, Molecular Pharmacology.

Targeting the Main Protease of SARS‐CoV‐2: From the Establishment of High Throughput Screening to the Design of Tailored Inhibitors

A. Schiedel, C. Müller, M. Gütschow, 2021, Angewandte Chemie.

Characterization of new G protein-coupled adenine receptors in mouse and hamster

A. Schiedel, C. Müller, D. Thimm, 2013, Purinergic Signalling.

G-Protein-Coupled Receptors: Sustained Signaling via Intracellular Megaplexes and Pathway-Specific Drugs.

C. Müller, A. Link, 2016, Angewandte Chemie.

P2 receptors activated by uracil nucleotides--an update.

C. Müller, A. Brunschweiger, 2006, Current medicinal chemistry.

Macrocyclic Gq Protein Inhibitors FR900359 and/or YM-254890-Fit for Translation?

C. Müller, B. Fleischmann, D. Wenzel, 2021, ACS pharmacology & translational science.

Analysis of the Staphylococcus aureus capsule biosynthesis pathway in vitro: characterization of the UDP-GlcNAc C6 dehydratases CapD and CapE and identification of enzyme inhibitors.

C. Müller, T. Schneider, K. O'Riordan, 2014, International journal of medical microbiology : IJMM.

Evaluation of anticonvulsant and analgesic effects of benzyl- and benzhydryl ureides.

C. Müller, M. Gütschow, T. Librowski, 2007, European journal of pharmacology.

Substrate-Dependence of Competitive Nucleotide Pyrophosphatase/Phosphodiesterase1 (NPP1) Inhibitors

C. Müller, P. Herdewijn, H. Stephan, 2017, Front. Pharmacol..

Electrophysiological and behavioural evidence for an antagonistic modulatory role of adenosine A2A receptors in dopamine D2 receptor regulation in the rat dopamine‐denervated striatum

K. Fuxe, C. Müller, I. Strömberg, 2000, The European journal of neuroscience.

Focused screening to identify new adenosine kinase inhibitors.

Meryem Köse, A. Schiedel, C. Müller, 2016, Bioorganic & medicinal chemistry.

Synthesis of BODIPY Derivatives Substituted with Various Bioconjugatable Linker Groups: A Construction Kit for Fluorescent Labeling of Receptor Ligands

C. Müller, J. Iqbal, A. El-Tayeb, 2013, Journal of Fluorescence.

Benzothiazinones: a novel class of adenosine receptor antagonists structurally unrelated to xanthine and adenine derivatives.

M. Paskaleva, C. Müller, M. Gütschow, 2012, Journal of medicinal chemistry.

2-Phenylimidazo[2,1-i]purin-5-ones: structure-activity relationships and characterization of potent and selective inverse agonists at Human A3 adenosine receptors.

K. Jacobson, C. Müller, M. Diekmann, 2003, Bioorganic & medicinal chemistry.

Synthesis and structure-activity relationships of deazaxanthines: analogs of potent A1- and A2-adenosine receptor antagonists.

C. Müller, S. Winiwarter, C. Mueller, 1994, Journal of medicinal chemistry.

Synthesis of paraxanthine analogs (1,7-disubstituted xanthines) and other xanthines unsubstituted at the 3-position: structure-activity relationships at adenosine receptors.

C. Müller, J. Daly, M. Manning, 1993, Journal of medicinal chemistry.

Phenylpropanolamine - a review. Von L. Lasagna; J. Wiley & Sons, Inc., New York/Chichester/Brisbane/Toronto/Singapore, 1988, 440 S., 40 Abb., 63 Tab., £ 34,50

C. Müller, 1989 .

Clopidogrel attenuates lithium-induced alterations in renal water and sodium channels/transporters in mice

C. Müller, B. Kishore, C. Ecelbarger, 2015, Purinergic Signalling.

Antinociceptive Effects of Novel A2B Adenosine Receptor Antagonists

C. Müller, A. Bilkei-Gorzo, A. Zimmer, 2004, Journal of Pharmacology and Experimental Therapeutics.

Anthraquinones As Pharmacological Tools and Drugs

C. Müller, E. Malik, 2016, Medicinal research reviews.

Facile synthesis of 5-amino- and 7-amino-6-azaoxindole derivatives

C. Müller, N. Tzvetkov, 2012 .

Chiral pyrrolo[2,3-d]pyrimidine and pyrimido[4,5-b]indole derivatives: structure-activity relationships of potent, highly stereoselective A1-adenosine receptor antagonists.

C. Müller, U. Geis, K. Eger, 1996, Journal of medicinal chemistry.

Synthesis and pharmacology of pyrido[2,3-d]pyrimidinediones bearing polar substituents as adenosine receptor antagonists.

C. Müller, D. Bertarelli, F. Fülle, 2006, Bioorganic & medicinal chemistry.

Adenosine Receptor Antagonists Including Caffeine Alter Fetal Brain Development in Mice

C. Métin, C. Müller, Â. R. Tomé, 2013, Science Translational Medicine.

Silva Development in Mice Adenosine Receptor Antagonists Including Caffeine Alter Fetal Brain

C. Métin, C. Müller, Â. R. Tomé, 2013 .

Development of pharmacological modulators for the orphan G protein-coupled receptor GPR 17 and their application for the investigation of molecular signal transduction pathways

C. Müller, Christa E. Müller, 2011 .

Synthesis of a hydrolytically stable, fluorescent-labeled ATP analog as a tool for probing adenylyl cyclases.

C. Müller, R. Seifert, A. Link, 2010, Bioorganic & medicinal chemistry letters.

Synthesis and biological activity of tricyclic aryloimidazo-, pyrimido-, and diazepinopurinediones.

A. Drabczyńska, O. Yuzlenko, C. Müller, 2006, Bioorganic & medicinal chemistry.

Diindolylmethane Derivatives: Potent Agonists of the Immunostimulatory Orphan G Protein-Coupled Receptor GPR84.

Meryem Köse, C. Müller, H. Weighardt, 2017, Journal of medicinal chemistry.

Synthese computergraphik berechneter high‐anti‐fixierter Pyrimidin‐Nucleosid‐Analoga mit potentieller virostatischer und antineoplastischer Wirksamkeit

C. Müller, G. Folkers, K. Eger, 1989 .

Thiazolo[3,2-a]benzimidazol-3(2H)-one derivatives: Structure-activity relationships of selective nucleotide pyrophosphatase/phosphodiesterase1 (NPP1) inhibitors.

Piet Herdewijn, C. Müller, P. Herdewijn, 2016, Bioorganic & medicinal chemistry.

Alkynyl-coumarinyl ethers as MAO-B inhibitors.

C. Müller, M. Gütschow, Sonja Hinz, 2014, Bioorganic & medicinal chemistry.

Imidazo[2,1-i]purin-5-ones and related tricyclic water-soluble purine derivatives: potent A(2A)- and A(3)-adenosine receptor antagonists.

Kenneth A Jacobson, K. Jacobson, C. Müller, 2002, Journal of medicinal chemistry.

Rapid microwave-assisted fluorination yielding novel 5'-deoxy-5'-fluorouridine derivatives.

C. Müller, H. Le, 2006, Bioorganic & medicinal chemistry letters.

Extracellular Metabolism of Nucleotides in Neuroblastoma × Glioma NG108-15 Cells Determined by Capillary Electrophoresis

C. Müller, Marko Kaulich, Ramatullah Qurishi, 2003, Cellular and Molecular Neurobiology.

Synthesis of Novel Pyrido[3,2‐e][1,2,4]triazolo[1,5‐c]pyrimidine Derivatives: Potent and Selective Adenosine A3 Receptor Antagonists

Meryem Köse, C. Müller, B. Chandrasekaran, 2013, Archiv der Pharmazie.

Synthesis and preliminary evaluation of new 1- and 3-[1-(2-hydroxy-3-phenoxypropyl)]xanthines from 2-amino-2-oxazolines as potential A1 and A2A adenosine receptor antagonists.

C. Müller, J. Leger, J. Bosc, 2006, Bioorganic & medicinal chemistry.

2-Amino-5-benzoyl-4-phenylthiazoles: Development of potent and selective adenosine A1 receptor antagonists.

C. Müller, Anja B Scheiff, S. Yerande, 2010, Bioorganic & medicinal chemistry.

Synthesis and pharmacological evaluation of coumarin derivatives as cannabinoid receptor antagonists and inverse agonists.

C. Müller, S. Bräse, Sonja Hinz, 2009, Bioorganic & medicinal chemistry.

Phenylethyl-substituted pyrimido[2,1-f]purinediones and related compounds: structure-activity relationships as adenosine A(1) and A(2A) receptor ligands.

A. Drabczyńska, O. Yuzlenko, A. Schiedel, 2007, Bioorganic & medicinal chemistry.

1-alkyl-8-(piperazine-1-sulfonyl)phenylxanthines: development and characterization of adenosine A2B receptor antagonists and a new radioligand with subnanomolar affinity and subtype specificity.

Thomas Borrmann, Sonja Hinz, C. Müller, 2009, Journal of medicinal chemistry.

GPR18 Inhibiting Amauromine and the Novel Triterpene Glycoside Auxarthonoside from the Sponge-Derived Fungus Auxarthron reticulatum

C. Müller, I. Arslan, S. Kehraus, 2015, Planta Medica.

Identification of a Potent and Selective Cannabinoid CB1 Receptor Antagonist from Auxarthron reticulatum.

C. Müller, G. Schnakenburg, S. Kehraus, 2011, ACS medicinal chemistry letters.

Synthesis of uracil nucleotide analogs with a modified, acyclic ribose moiety as P2Y(2) receptor antagonists.

C. Müller, Marko Kaulich, A. El-Tayeb, 2009, Bioorganic & medicinal chemistry.

Synthesis and structure-activity relationships of uracil nucleotide derivatives and analogues as agonists at human P2Y2, P2Y4, and P2Y6 receptors.

C. Müller, Christa E Müller, Ali El-Tayeb, 2006, Journal of medicinal chemistry.

Synthesis of alkyl- and aryl-amino-substituted anthraquinone derivatives by microwave-assisted copper(0)-catalyzed Ullmann coupling reactions

C. Müller, Y. Baqi, Younis Baqi, 2010, Nature Protocols.

Imidazo[2,1-b]thiazepines: synthesis, structure and evaluation of benzodiazepine receptor binding.

C. Müller, K. Kieć‐Kononowicz, B. Michalak, 2004, European journal of medicinal chemistry.

Imidazo[2,1-b]thiazoles, imidazo[2,1-b]imidazoles and Pyrrolo[1,2-c]imidazoles. synthesis, structure and evaluation of benzodiazepine receptor binding

J. Handzlik, C. Müller, K. Kieć‐Kononowicz, 2002 .

Regioselective synthesis of 7,8-dihydroimidazo[5,1-c][1,2,4]triazine-3,6(2H,4H)-dione derivatives: A new drug-like heterocyclic scaffold

C. Müller, N. Tzvetkov, H. Euler, 2012, Beilstein journal of organic chemistry.

Syntheses of 2-substituted 1-amino-4-bromoanthraquinones (bromaminic acid analogues) – precursors for dyes and drugs

C. Müller, Y. Baqi, E. Malik, 2015, Beilstein journal of organic chemistry.

Discovery and structure-relationships of salicylanilide derivatives as potent, non-acidic P2X1 receptor antagonists.

C. Müller, R. Schmid, E. Fuentes, 2020, Journal of medicinal chemistry.

Ullmann reactions of 1-amino-4-bromoanthraquinones bearing various 2-substituents furnishing novel dyes

C. Müller, Y. Baqi, L. M. Wingen, 2016 .

A SIMPLE METHOD TO PREPARE HOMOALLYLIC AMINES FROM SECONDARY HOMOALLYLIC MESYLATES

C. Müller, J. Muzart, F. Hénin, 1995 .

Structure-activity relationships of adenine and deazaadenine derivatives as ligands for adenine receptors, a new purinergic receptor family.

A. Schiedel, C. Müller, G. Cristalli, 2009, Journal of medicinal chemistry.

Decarboxylative Coupling Reaction of 2‐(1 H ‐Indol‐3‐yl)acetic Acids with Indole, Azaindole, Benzimidazole and Indazole Derivatives

C. Müller, G. Schnakenburg, M. Uzair, 2019, Advanced Synthesis & Catalysis.

Uridine Nucleotide Receptors and Their Ligands: Structural, Physiological, and Pathophysiological Aspects, with Special Emphasis on the Nervous System

C. Müller, E. Heilbronn, B. Knoblauch, 1997, Neurochemical Research.

Adenine-(methoxy)-ethoxy-Pα,α-dithio-triphosphate inhibits pathologic calcium pyrophosphate deposition in osteoarthritic human chondrocytes.

C. Müller, J. Sévigny, J. Pelletier, 2019, Organic & biomolecular chemistry.

Efficient and mild deamination procedure for 1-aminoanthraquinones yielding a diverse library of novel derivatives with potential biological activity

C. Müller, Y. Baqi, Younis Baqi, 2012 .

6-Bromo-8-(4-[(3)H]methoxybenzamido)-4-oxo-4H-chromene-2-carboxylic Acid: a powerful tool for studying orphan G protein-coupled receptor GPR35.

C. Müller, D. Thimm, Anne Meyer, 2013, Journal of medicinal chemistry.

8-Benzamidochromen-4-one-2-carboxylic acids: potent and selective agonists for the orphan G protein-coupled receptor GPR35.

A. Schiedel, C. Müller, D. Thimm, 2013, Journal of medicinal chemistry.

Polyoxometalates--a new class of potent ecto-nucleoside triphosphate diphosphohydrolase (NTPDase) inhibitors.

C. Müller, H. Stephan, Y. Baqi, 2006, Bioorganic & medicinal chemistry letters.

Polyoxometalates as Versatile Enzyme Inhibitors

C. Müller, F. Emmerling, H. Stephan, 2013 .

Fast, Efficient, and Versatile Synthesis of 6-amino-5-carboxamidouracils as Precursors for 8-Substituted Xanthines

C. Müller, G. Schnakenburg, Matthias S. Scholz, 2019, Front. Chem..

2-phenyl-1-[4-(2-piperidine-1-yl-ethoxy)benzyl]-1H-benzimidazoles as ligands for the estrogen receptor: synthesis and pharmacological evaluation.

A. Schiedel, C. Müller, R. Gust, 2010, Bioorganic & medicinal chemistry.

Dopamine/adenosine interactions related to locomotion and tremor in animal models: possible relevance to parkinsonism.

J. Salamone, M. Correa, A. Farrar, 2008, Parkinsonism & related disorders.

Lignans isolated from valerian: identification and characterization of a new olivil derivative with partial agonistic activity at A(1) adenosine receptors.

Josef Hölzl, Sonja Hess, C. Müller, 2002, Journal of natural products.

Cyclopropane-Containing Fatty Acids from the Marine Bacterium Labrenzia sp. 011 with Antimicrobial and GPR84 Activity

Meryem Köse, C. Müller, S. Kehraus, 2018, Marine drugs.

Chromenones as Multineurotargeting Inhibitors of Human Enzymes

C. Müller, M. Gütschow, C. D. Beadle, 2019, ACS omega.

S. Schiffmann, L. Buée, C. Müller, 2018, Molecular Psychiatry.

The experimental power of FR900359 to study Gq-regulated biological processes

H. Dohlman, C. Müller, M. Hesse, 2015, Nature Communications.

A novel receptor cross-talk between the ATP receptor P2Y2 and formyl peptide receptors reactivates desensitized neutrophils to produce superoxide.

Tudor I. Oprea, T. Oprea, C. Müller, 2014, Experimental cell research.

Chronic and acute adenosine A2A receptor blockade prevents long-term episodic memory disruption caused by acute cannabinoid CB1 receptor activation

C. Müller, Y. Baqi, J. Coelho, 2017, Neuropharmacology.

Recent developments in adenosine A2A receptor ligands.

C. Müller, G. Cristalli, R. Volpini, 2009, Handbook of experimental pharmacology.

Involvement of Adenosine A1 and A2A Receptors in the Motor Effects of Caffeine after its Acute and Chronic Administration

Katerina Antoniou, Sergi Ferré, K. Fuxe, 2003, Neuropsychopharmacology.

Radiosynthesis and in vivo evaluation of a fluorine-18 labeled pyrazine based radioligand for PET imaging of the adenosine A2B receptor.

C. Müller, J. Steinbach, P. Brust, 2018, Bioorganic & medicinal chemistry.

Indoloditerpenes from a marine-derived fungal strain of Dichotomomyces cejpii with antagonistic activity at GPR18 and cannabinoid receptors.

C. Müller, S. Kehraus, G. König, 2014, Journal of natural products.

Preparation of enantiopure (R)-hydroxy metabolite of denbufylline using immobilized Lactobacillus kefiri DSM 20587 as a catalyst.

C. Müller, E. Pękala, J. Burbiel, 2009, Chirality.

Advances in immobilized enzyme microbioreactors in capillary electrophoresis.

Jamshed Iqbal, C. Müller, J. Iqbal, 2013, The Analyst.

Synthesis of xanthine derivatives by microwave-assisted ring closure reaction

C. Müller, J. Hockemeyer, J. Burbiel, 2005 .

Rapid and efficient microwave-assisted copper(0)-catalyzed ullmann coupling reaction: general access to anilinoanthraquinone derivatives.

C. Müller, Y. Baqi, Younis Baqi, 2007, Organic letters.

Allosteric modulators of rhodopsin-like G protein-coupled receptors: opportunities in drug development.

Younis Baqi, A. Schiedel, C. Müller, 2012, Pharmacology & therapeutics.

Novel amino acid derived natural products from the ascidian Atriolum robustum: identification and pharmacological characterization of a unique adenosine derivative.

C. Müller, S. Kehraus, A. Wright, 2004, Journal of medicinal chemistry.

Nucleotide pyrophosphatase/phosphodiesterase 1 (NPP1) and its inhibitors.

C. Müller, Sang-Yong Lee, 2017, MedChemComm.

A new synthesis of thiophosphoric acid esters with a C-S-P bond

C. Müller, H. Roth, 1990 .

Formation of 7,9-Disubstituted Xanthinium Compounds Under Mild Conditions by Alkylation of Silylated Xanthines

C. Müller, 1994 .

Adenosine/dopamine interaction: implications for the treatment of Parkinson's disease.

C. Müller, I. Strömberg, S. Ferré, 2001, Parkinsonism & related disorders.

Medicinal chemistry of adenosine, P2Y and P2X receptors

K. Jacobson, C. Müller, 2016, Neuropharmacology.

5-Substituted UTP derivatives as P2Y2 receptor agonists

M. Wikström, C. Müller, T. Kottke, 1999 .

Adenosine receptor agonists: from basic medicinal chemistry to clinical development

C. Müller, J. Burbiel, Luo Yan, 2003, Expert opinion on emerging drugs.

Synthesis of 3-substituted 6-aminouracils

C. Müller, 1991 .

Synthesis of Paraxanthine and Isoparaxanthine Analogs (1,7- and 1,9-Substituted Xanthine Derivatives)

C. Müller, M. Pawłowski, D. Deters, 1998 .

Stimulation of calcium release by caffeine analogs in pheochromocytoma cells.

C. Müller, J. Daly, 1993, Biochemical pharmacology.

Synthesis and Properties of a New Water-Soluble Prodrug of the Adenosine A2A Receptor Antagonist MSX-2

C. Müller, J. Hockemeyer, Ramatullah Qurishi, 2008, Molecules.

Interaction of Approved Drugs with Synaptic Vesicle Protein 2A

A. Schiedel, C. Müller, V. Namasivayam, 2017, Archiv der Pharmazie.

A2B Adenosine Receptor Antagonists with Picomolar Potency.

C. Müller, Y. Baqi, V. Namasivayam, 2019, Journal of medicinal chemistry.

5,5'-BIPYRIDYL-2,4,6,2',4',6'-HEXAONE DERIVATIVES (HYDURILIC ACIDS) : SYNTHESES, MECHANISM OF C-C-BOND FORMATION AND PROPERTIES OF THE DIMERIC BARBITURIC ACID DERIVATIVES

C. Müller, C. Roegler, J. Hockemeyer, 2009 .

Characterization of human and rodent native and recombinant adenosine A2B receptors by radioligand binding studies

C. Müller, E. Verspohl, J. Iqbal, 2006, Purinergic Signalling.

Crystal structure of 1-propyl-8-(4-sulfophenyl)-7H-imidazo[4,5-d]pyrimidin- 2,6(1H,3H)-dione dihydrate, C14H14N4O5S 2H2O

C. Müller, A. Kirfel, F. Schwabenländer, 1997 .

Crystal structure of 1-propyl-8-(4-sulfophenyl)-7H-imidazo[4,5-d]pyrimidin- 2,6(1H,3H)-dione dihydrate, C14H14N4O5S 2H2O

C. Müller, A. Kirfel, F. Schwabenländer, 1997 .

SC20 a new versatile strategy for the synthesis of xanthines with high adenosine receptor affinity and subtype-selectivity

C. Müller, 1994 .

Adenosine receptor ligands-recent developments part I. Agonists.

C. Müller, 2000 .

2-Substituted α,β Methylene-ADP Derivatives: Potent Competitive Ecto-5'-nucleotidase (CD73) Inhibitors with Variable Binding Modes.

C. Müller, N. Sträter, J. Pippel, 2020, Journal of medicinal chemistry.

Adenosine receptors and their modulators.

C. Müller, T. Scior, C E Müller, 1993, Pharmaceutica acta Helvetiae.

Differential allosteric modulation by amiloride analogues of agonist and antagonist binding at A(1) and A(3) adenosine receptors.

K. Jacobson, A. IJzerman, C. Müller, 2003, Biochemical Pharmacology.

Recent developments in adenosine receptor ligands and their potential as novel drugs.

Kenneth A Jacobson, K. Jacobson, C. Müller, 2011, Biochimica et biophysica acta.

Structure-activity relationships of flavonoids as inhibitors of breast cancer resistance protein (BCRP).

Michael Wiese, Ralf Mayer, Heinz Bönisch, 2011, Bioorganic & medicinal chemistry.

Adenosine receptor subtype-selective antagonists in inflammation and hyperalgesia

Christa E. Müller, Andreas Zimmer, C. Müller, 2008, Naunyn-Schmiedeberg's Archives of Pharmacology.

Neuroprotective potential of adenosine A2A and cannabinoid CB1 receptor antagonists in an animal model of Parkinson disease.

J. Lanciego, C. Müller, R. Franco, 2014, Journal of neuropathology and experimental neurology.

Adenosine A2A receptor antagonists exert motor and neuroprotective effects by distinct cellular mechanisms

C. Müller, R. Cunha, Liqun Yu, 2008, Annals of neurology.

General Synthesis of Unsymmetrical 3,3'-(Aza)diindolylmethane Derivatives.

C. Müller, G. Schnakenburg, E. Górska, 2018, The Journal of organic chemistry.

Magnolia Extract, Magnolol, and Metabolites: Activation of Cannabinoid CB2 Receptors and Blockade of the Related GPR55.

T. Karcz, C. Müller, M. Lehr, 2013, ACS medicinal chemistry letters.

Koala and Wombat Gammaherpesviruses Encode the First Known Viral NTPDase Homologs and Are Phylogenetically Divergent from All Known Gammaherpesviruses

C. Müller, G. Browning, J. Devlin, 2018, Journal of Virology.

Development of Anthraquinone Derivatives as Ectonucleoside Triphosphate Diphosphohydrolase (NTPDase) Inhibitors With Selectivity for NTPDase2 and NTPDase3

C. Müller, J. Sévigny, J. Pelletier, 2020, Frontiers in Pharmacology.

Antithrombotic P2Y12 receptor antagonists: recent developments in drug discovery.

C. Müller, Y. Baqi, Younis Baqi, 2019, Drug discovery today.

Molecular Recognition of Agonists and Antagonists by the Nucleotide-Activated G Protein-Coupled P2Y2 Receptor.

C. Müller, Y. Baqi, Alexander Neumann, 2017, Journal of medicinal chemistry.

Development of Potent and Selective Antagonists for the UTP-Activated P2Y4 Receptor.

C. Müller, Y. Baqi, Alexander Neumann, 2017, Journal of medicinal chemistry.

Crystal structure of NTPDase2 in complex with the sulfoanthraquinone inhibitor PSB-071.

C. Müller, N. Sträter, Y. Baqi, 2014, Journal of structural biology.

Discovery of potent competitive antagonists and positive modulators of the P2X2 receptor.

C. Müller, G. Schmalzing, Y. Baqi, 2011, Journal of medicinal chemistry.

Interaction of New, Very Potent Non-Nucleotide Antagonists with Arg256 of the Human Platelet P2Y12 Receptor

Younis Baqi, Kristina Hoffmann, C. Müller, 2009, Journal of Pharmacology and Experimental Therapeutics.

High-affinity, non-nucleotide-derived competitive antagonists of platelet P2Y12 receptors.

Meryem Köse, C. Müller, Y. Baqi, 2009, Journal of medicinal chemistry.

Combinatorial synthesis of anilinoanthraquinone derivatives and evaluation as non-nucleotide-derived P2Y2 receptor antagonists.

C. Müller, Y. Baqi, Petra Hillmann, 2008, Bioorganic & medicinal chemistry letters.

Cloning and expression of deoxyhypusine synthase from Plasmodium vivax and Theileria parva as an approach for target evaluation in antiparasitic chemotherapy

C. Müller, J. Njuguna, P. Kamau, 2009 .

Update of P2X receptor properties and their pharmacology: IUPHAR Review 30

F. Di Virgilio, K. Jacobson, C. Müller, 2020, British journal of pharmacology.

Prasugrel suppresses development of lithium-induced nephrogenic diabetes insipidus in mice

C. Müller, B. Kishore, C. Ecelbarger, 2016, Purinergic Signalling.

Metabotropic glutamate mGlu5 receptor-mediated modulation of the ventral striopallidal GABA pathway in rats. Interactions with adenosine A2A and dopamine D2 receptors

K. Fuxe, Z. Díaz-Cabiale, C. Müller, 2002, Neuroscience Letters.

Potent Suppressive Effects of 1-Piperidinylimidazole Based Novel P2X7 Receptor Antagonists on Cancer Cell Migration and Invasion.

Darren R. Williams, C. Müller, Jeong-min Lee, 2016, Journal of medicinal chemistry.

Antagonistic cannabinoid CB1/dopamine D2 receptor interactions in striatal CB1/D2 heteromers. A combined neurochemical and behavioral analysis

K. Fuxe, G. Fisone, D. Marcellino, 2008, Neuropharmacology.

Discovery of potent nucleotide pyrophosphatase/phosphodiesterase3 (NPP3) inhibitors with ancillary carbonic anhydrase inhibition for cancer (immuno)therapy.

C. Müller, C. Supuran, N. Boshta, 2021, RSC medicinal chemistry.

Role of extracellular cysteine residues in the adenosine A2A receptor

A. Schiedel, C. Müller, V. Namasivayam, 2016, Purinergic Signalling.

Ligand-specific binding and activation of the human adenosine A(2B) receptor.

Farag F. Sherbiny, A. Schiedel, C. Müller, 2013, Biochemistry.

Characterization of non-olfactory GPCRs in human sperm with a focus on GPR18

C. Müller, K. Kieć‐Kononowicz, C. Becker, 2016, Scientific Reports.

An experimental strategy to probe Gq contribution to signal transduction in living cells

C. Müller, E. Kostenis, A. Inoue, 2021, The Journal of biological chemistry.

The caffeine-binding adenosine A2A receptor induces age-like HPA-axis dysfunction by targeting glucocorticoid receptor function

L. Buée, C. Müller, S. Meijsing, 2016, Scientific Reports.

GPR55: A therapeutic target for Parkinson's disease?

C. Müller, R. Franco, J. Oyarzábal, 2017, Neuropharmacology.

GPR 55 : A therapeutic target for Parkinson ' s disease ?

C. Müller, R. Franco, M. Ramírez, 2017 .

J. Salamone, M. Correa, C. Müller, 2016, Psychopharmacology.

J. Salamone, M. Correa, E. Nunes, 2014, Psychopharmacology.

Correction to: Identification of adenine-N9-(methoxy)ethyl-β-bisphosphonate as NPP1 inhibitor attenuates NPPase activity in human osteoarthritic chondrocytes

C. Müller, J. Sévigny, J. Pelletier, 2019, Purinergic Signalling.

Identification of adenine-N9-(methoxy)ethyl-β-bisphosphonate as NPP1 inhibitor attenuates NPPase activity in human osteoarthritic chondrocytes

C. Müller, J. Sévigny, J. Pelletier, 2019, Purinergic Signalling.

ASSOCIATE EDITOR: ELIOT OHLSTEIN International Union of Basic andClinical Pharmacology. CXII: Adenosine Receptors: A Further Update

K. Jacobson, A. IJzerman, C. Müller, 2022 .

A novel P2X2‐dependent purinergic mechanism of enteric gliosis in intestinal inflammation

C. Müller, S. Wehner, Y. Baqi, 2020, EMBO molecular medicine.

Structure-Activity Relationship of Purine and Pyrimidine Nucleotides as Ecto-5'-Nucleotidase (CD73) Inhibitors.

K. Jacobson, C. Müller, R. Balasubramanian, 2019, Journal of medicinal chemistry.

Synthesis, characterization, and in vitro evaluation of the selective P2Y2 receptor antagonist AR-C118925

C. Müller, Aliaa Abdelrahman, Muhammad Rafehi, 2017, Purinergic Signalling.

A capillary electrophoresis method for the characterization of ecto-nucleoside triphosphate diphosphohydrolases (NTPDases) and the analysis of inhibitors by in-capillary enzymatic microreaction

C. Müller, J. Iqbal, H. Zimmermann, 2005, Purinergic Signalling.

P 2 Y 2 and G q / G 11 control blood pressure by mediating endothelial mechanotransduction

C. Müller, I. Fleming, S. Offermanns, 2019 .

P2Y₂ and Gq/G₁₁ control blood pressure by mediating endothelial mechanotransduction.

C. Müller, I. Fleming, S. Offermanns, 2015, The Journal of clinical investigation.

Medicinal chemistry of a2B adenosine receptors

C. Müller, Y. Baqi, V. Namasivayam, 2018 .

8-Benzylaminoxanthine scaffold variations for selective ligands acting on adenosine A2A receptors. Design, synthesis and biological evaluation.

K. Kuder, C. Müller, K. Kieć‐Kononowicz, 2020, Bioorganic chemistry.

Xanthines as adenosine receptor antagonists.

K. Jacobson, C. Müller, 2011, Handbook of experimental pharmacology.

Striatal Adenosine A2A and Cannabinoid CB1 Receptors Form Functional Heteromeric Complexes that Mediate the Motor Effects of Cannabinoids

F. Ciruela, C. Müller, R. Moratalla, 2007, Neuropsychopharmacology.

6-(Ar)Alkylamino-Substituted Uracil Derivatives: Lipid Mimetics with Potent Activity at the Orphan G Protein-Coupled Receptor 84 (GPR84)

Meryem Köse, C. Müller, I. von Kügelgen, 2018, ACS omega.

Development of Polar Adenosine A2A Receptor Agonists for Inflammatory Bowel Disease: Synergism with A2B Antagonists.

C. Müller, K. Nieber, A. El-Tayeb, 2011, ACS medicinal chemistry letters.

Selectivity is species-dependent: Characterization of standard agonists and antagonists at human, rat, and mouse adenosine receptors

A. Schiedel, C. Müller, Sonja Hinz, 2015, Purinergic Signalling.

Identification of aurintricarboxylic acid as a potent allosteric antagonist of P2X1 and P2X3 receptors

C. Müller, M. Schaefer, G. Schmalzing, 2019, Neuropharmacology.

Cellular localization of adenine receptors in the rat kidney and their functional significance in the inner medullary collecting duct.

A. Schiedel, C. Müller, D. Kohan, 2013, American journal of physiology. Renal physiology.

Characterization of new G protein-coupled adenine receptors in mouse and hamster

A. Schiedel, C. Müller, D. Thimm, 2013, Purinergic Signalling.

The rat adenine receptor: pharmacological characterization and mutagenesis studies to investigate its putative ligand binding site

A. Schiedel, C. Müller, P. Rosa, 2013, Purinergic Signalling.

Shear stress modulates endothelial KLF2 through activation of P2X4

B. Olde, C. Müller, D. Erlinge, 2015, Purinergic Signalling.

Interaction of Purinergic P2X4 and P2X7 Receptor Subunits

C. Müller, G. Schmalzing, F. Markwardt, 2017, Front. Pharmacol..

Induction of oral tremor in mice by the acetylcholinesterase inhibitor galantamine: Reversal with adenosine A2A antagonism

J. Salamone, M. Correa, C. Müller, 2016, Pharmacology Biochemistry and Behavior.

Oral tremor induced by galantamine in rats: A model of the parkinsonian side effects of cholinomimetics used to treat Alzheimer's disease

J. Salamone, J. J. Chrobak, C. Müller, 2011, Pharmacology Biochemistry and Behavior.

Oral tremor induced by the muscarinic agonist pilocarpine is suppressed by the adenosine A2A antagonists MSX-3 and SCH58261, but not the adenosine A1 antagonist DPCPX

J. Salamone, J. J. Chrobak, C. Müller, 2010, Pharmacology Biochemistry and Behavior.

Memory deficits induced by chronic cannabinoid exposure are prevented by adenosine A2AR receptor antagonism

A. Köfalvi, C. Müller, Y. Baqi, 2019, Neuropharmacology.

Structural and Conformational Studies on Carboxamides of 5,6-Diaminouracils—Precursors of Biologically Active Xanthine Derivatives

C. Müller, S. Grimme, G. Schnakenburg, 2019, Molecules.

Nucleotide Analog ARL67156 as a Lead Structure for the Development of CD39 and Dual CD39/CD73 Ectonucleotidase Inhibitors

C. Müller, J. Sévigny, J. Pelletier, 2020, Frontiers in Pharmacology.

Beneficial Effect of a Selective Adenosine A2A Receptor Antagonist in the APPswe/PS1dE9 Mouse Model of Alzheimer’s Disease

L. Buée, C. Müller, M. Heneka, 2018, Front. Mol. Neurosci..

Applying Molecular Networking for the Detection of Natural Sources and Analogues of the Selective Gq Protein Inhibitor FR900359.

C. Müller, E. Kostenis, S. Kehraus, 2018, Journal of natural products.

Thermal proteome profiling identifies the membrane-bound purinergic receptor P2X4 as a target of the autophagy inhibitor indophagolin.

C. Müller, H. Waldmann, P. Janning, 2021, Cell chemical biology.

Capillary electrophoresis-based nanoscale assays for monitoring ecto-5'-nucleotidase activity and inhibition in preparations of recombinant enzyme and melanoma cell membranes.

C. Müller, J. Iqbal, H. Zimmermann, 2008, Analytical biochemistry.

l-DOPA-treatment in primates disrupts the expression of A2A adenosine–CB1 cannabinoid–D2 dopamine receptor heteromers in the caudate nucleus

J. Lanciego, N. Luquin, C. Müller, 2014, Neuropharmacology.

Caffeine and an adenosine A2A receptor antagonist prevent memory impairment and synaptotoxicity in adult rats triggered by a convulsive episode in early life

D. Souza, C. Müller, P. Agostinho, 2010, Journal of neurochemistry.

Structure-activity relationships of agonists for the orphan G protein-coupled receptor GPR27.

C. Müller, T. Kronenberger, J. Hanson, 2021, European journal of medicinal chemistry.

Effect of trifluoromethyl and other substituents on activity of xanthines at adenosine receptors.

K. Jacobson, C. Müller, J. Daly, 1993, Journal of medicinal chemistry.

Bicyclic imidazole-4-one derivatives: a new class of antagonists for the orphan G protein-coupled receptors GPR18 and GPR55

T. Karcz, C. Müller, K. Kieć‐Kononowicz, 2014 .

Antagonists for the orphan G-protein-coupled receptor GPR55 based on a coumarin scaffold.

C. Müller, S. Bräse, M. Nieger, 2013, Journal of medicinal chemistry.

Adenosine A2A agonist and A2B antagonist mediate an inhibition of inflammation-induced contractile disturbance of a rat gastrointestinal preparation

C. Müller, F. Michel, K. Nieber, 2010, Purinergic Signalling.

A detailed behavioral analysis of the acute motor effects of caffeine in the rat: involvement of adenosine A1 and A2A receptors

C. Müller, L. Panlilio, S. Goldberg, 2005, Psychopharmacology.

Effects of GPR18 Ligands on Body Weight and Metabolic Parameters in a Female Rat Model of Excessive Eating

C. Müller, K. Kieć‐Kononowicz, J. Sapa, 2021, Pharmaceuticals.

Preparation, properties, reactions, and adenosine receptor affinities of sulfophenylxanthine nitrophenyl esters: toward the development of sulfonic acid prodrugs with peroral bioavailability.

C. Müller, Luo Yan, 2004, Journal of medicinal chemistry.

Imidazo-thiazine, -diazinone and -diazepinone derivatives. Synthesis, structure and benzodiazepine receptor binding.

C. Müller, K. Kieć‐Kononowicz, E. Szymańska, 2001, European journal of medicinal chemistry.

[3H]BQ-123 Binding to Native Endothelin ETA Receptors in Human Astrocytoma 1321N1 Cells and Screening of Potential Ligands

C. Müller, Kerstin J Griessmeier, 2005, Pharmacology.

Substituted 4-phenylthiazoles: Development of potent and selective A1, A3 and dual A1/A3 adenosine receptor antagonists.

C. Müller, V. Namasivayam, S. Yerande, 2019, European journal of medicinal chemistry.

Development of a selective and highly sensitive fluorescence assay for nucleoside triphosphate diphosphohydrolase1 (NTPDase1, CD39).

C. Müller, J. Sévigny, H. Stephan, 2018, The Analyst.

Characterization of P2X4 receptor agonists and antagonists by calcium influx and radioligand binding studies

J. Bajorath, Meryem Köse, A. Schiedel, 2017, Biochemical pharmacology.

Virtual screening identifies novel sulfonamide inhibitors of ecto-5'-nucleotidase.

J. Bajorath, C. Müller, Peter Ripphausen, 2012, Journal of medicinal chemistry.

Investigation on 2',3'-O-Substituted ATP Derivatives and Analogs as Novel P2X3 Receptor Antagonists.

C. Müller, G. Marucci, M. Buccioni, 2018, ACS medicinal chemistry letters.

Selective Activation of Adenosine A2A Receptors on Immune Cells by a CD73-Dependent Prodrug Suppresses Joint Inflammation in Experimental Rheumatoid Arthritis

C. Müller, U. Flögel, C. Jacoby, 2012, Science Translational Medicine.

Adenosine Receptors: New Targets to Protect Against Tissue Damage in Inflammatory Bowel Symptoms

C. Müller, O. Kelber, K. Nieber, 2012 .

Adenosine A2A receptor contributes to the anti-inflammatory effect of the fixed herbal combination STW 5 (Iberogast®) in rat small intestinal preparations

C. Müller, O. Kelber, H. Abdel-Aziz, 2012, Naunyn-Schmiedeberg's Archives of Pharmacology.

N9-benzyl-substituted 1,3-dimethyl- and 1,3-dipropyl-pyrimido[2,1-f]purinediones: synthesis and structure-activity relationships at adenosine A1 and A2A receptors.

A. Drabczyńska, O. Yuzlenko, A. Schiedel, 2007, Bioorganic & medicinal chemistry.

Involvement of adenosine A1 receptors in the discriminative-stimulus effects of caffeine in rats

C. Müller, S. Goldberg, Z. Justinova, 2005, Psychopharmacology.

Ecto-ATPase inhibition: ATP and adenosine release under physiological and ischemic in vivo conditions in the rat striatum

C. Müller, F. Pedata, P. Bruni, 2012, Experimental Neurology.

Homology modelling of the human adenosine A2B receptor based on X-ray structures of bovine rhodopsin, the β2-adrenergic receptor and the human adenosine A2A receptor

Farag F. Sherbiny, Anke C. Schiedel, Astrid Maaß, 2009, J. Comput. Aided Mol. Des..

A1-Adenosine receptor antagonists

C. Müller, Christa E Müller, 1997 .

Enzymatic Properties of an Ecto-nucleoside Triphosphate Diphosphohydrolase from Legionella pneumophila

C. Müller, T. Beddoe, J. Rossjohn, 2008, Journal of Biological Chemistry.

Adenosine A2A receptor blockade prevents memory dysfunction caused by β-amyloid peptides but not by scopolamine or MK-801

C. Müller, R. Cunha, C. Oliveira, 2008, Experimental Neurology.

A Group of Cationic Amphiphilic Drugs Activates MRGPRX2 and Induces Scratching Behavior in Mice.

C. Müller, M. Neurath, Xinzhong Dong, 2021, The Journal of allergy and clinical immunology.

Ligand binding and activation of UTP-activated G protein-coupled P2Y2 and P2Y4 receptors elucidated by mutagenesis, pharmacological and computational studies.

C. Müller, Y. Baqi, Alexander Neumann, 2019, Biochimica et biophysica acta. General subjects.

P76 synthesis and adenosine receptor affinity of S-substituted 2-thioxanthine analogues

C. Müller, D. Deters, A. Dominik, 1994 .

Water-soluble phosphate prodrugs of 1-propargyl-8-styrylxanthine derivatives, A(2A)-selective adenosine receptor antagonists.

K. Klotz, C. Müller, F. Fülle, 2000, Journal of medicinal chemistry.

A2A‐selective adenosine receptor antagonists: Development of water‐soluble prodrugs and a new tritiated radioligand

W. Hauber, K. Klotz, C. Müller, 1998 .

Binding of [3H]MSX-2 (3-(3-hydroxypropyl)-7-methyl-8-(m-methoxystyryl)-1-propargylxanthine) to rat striatal membranes--a new, selective antagonist radioligand for A(2A) adenosine receptors.

C. Müller, R. Sauer, J. Maurinsh, 2000, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

BAY60-6583 Acts as a Partial Agonist at Adenosine A2B Receptors

C. Müller, Benjamin F. Seibt, Sonja Hinz, 2014, The Journal of Pharmacology and Experimental Therapeutics.

The impact of adenosine and A2B receptors on glucose homoeostasis

C. Müller, E. Verspohl, D. Rüsing, 2006, The Journal of pharmacy and pharmacology.

Structural analogues of the natural products magnolol and honokiol as potent allosteric potentiators of GABA(A) receptors.

C. Müller, E. Sigel, R. Baur, 2014, Bioorganic & medicinal chemistry.

Chemical Genetic Analysis and Functional Characterization of Staphylococcal Wall Teichoic Acid 2-Epimerases Reveals Unconventional Antibiotic Drug Targets

C. Müller, T. Roemer, Xinwei Sher, 2016, PLoS pathogens.

Soluble and membrane-bound adenylate kinase and nucleotidases augment ATP-mediated inflammation in diabetic retinopathy eyes with vitreous hemorrhage

C. Müller, S. Jalkanen, K. Lehti, 2019, Journal of Molecular Medicine.

A capillary electrophoresis method with dynamic pH junction stacking for the monitoring of cerebroside sulfotransferase.

C. Müller, V. Gieselmann, Wenjin Li, 2015, Journal of chromatography. A.

Stimulant effects of adenosine antagonists on operant behavior: differential actions of selective A2A and A1 antagonists

J. Salamone, A. Farrar, E. Nunes, 2011, Psychopharmacology.

Past, present and future of A(2A) adenosine receptor antagonists in the therapy of Parkinson's disease.

J. Lanciego, C. Müller, R. Franco, 2011, Pharmacology & therapeutics.

Ecto-5′-Nucleotidase (CD73)-Mediated Formation of Adenosine Is Critical for the Striatal Adenosine A2A Receptor Functions

C. Müller, R. Cunha, J. Sévigny, 2013, The Journal of Neuroscience.

8‐Benzyltetrahydropyrazino[2,1‐f]purinediones: Water‐Soluble Tricyclic Xanthine Derivatives as Multitarget Drugs for Neurodegenerative Diseases

Meryem Köse, C. Müller, P. Koch, 2014, ChemMedChem.

Competitive mode and site of interaction of ticagrelor at the human platelet P2Y12‐receptor

C. Müller, K. Hoffmann, Younis Baqi, 2014, Journal of thrombosis and haemostasis : JTH.

Unraveling binding mechanism and kinetics of macrocyclic Gαq protein inhibitors.

C. Müller, E. Kostenis, R. Guixà-González, 2021, Pharmacological research.

P2Y receptors in GtoPdb v.2023.1

G. Burnstock, K. Jacobson, C. Müller, 2023, IUPHAR/BPS Guide to Pharmacology CITE.

Ethanol and Caffeine Effects on Social Interaction and Recognition in Mice : Involvement of Adenosine A 2 A and A 1 Receptors Journal Item

J. Salamone, M. Correa, C. Müller, 2019 .

Ethanol and Caffeine Effects on Social Interaction and Recognition in Mice: Involvement of Adenosine A2A and A1 Receptors

J. Salamone, M. Correa, C. Müller, 2016, Front. Behav. Neurosci..

Elucidating the active δ-opioid receptor crystal structure with peptide and small-molecule agonists

R. Stevens, C. Müller, V. Katritch, 2019, Science Advances.

Feature-Based Molecular Networking for the Targeted Identification of Gq-Inhibiting FR900359 Derivatives.

C. Müller, E. Kostenis, S. Kehraus, 2021, Journal of natural products.

Thioesterase-mediated side chain transesterification generates potent Gq signaling inhibitor FR900359

C. Müller, M. Gütschow, E. Kostenis, 2021, Nature communications.

Versatile, convenient synthesis of pyrimido[1,2,3-cd]purinediones

C. Müller, A. Hayallah, Stefanie Weyler, 2003 .

Carbamazepine derivatives with P2X4 receptor-blocking activity.

C. Müller, Sonja Hinz, S. Dosa, 2014, Bioorganic & medicinal chemistry.

Recent progress in the development of adenosine receptor ligands as antiinflammatory drugs.

C. Müller, R. Akkari, J. Hockemeyer, 2006, Current topics in medicinal chemistry.

Impact of in vivo chronic blockade of adenosine A2A receptors on the BDNF-mediated facilitation of LTP

C. Müller, Luísa V. Lopes, A. Sebastião, 2014, Neuropharmacology.

Preliminary Evidence of the Potent and Selective Adenosine A2B Receptor Antagonist PSB-603 in Reducing Obesity and Some of Its Associated Metabolic Disorders in Mice

C. Müller, K. Kieć‐Kononowicz, M. Bednarski, 2022, International journal of molecular sciences.

Caffeine acts through neuronal adenosine A2A receptors to prevent mood and memory dysfunction triggered by chronic stress

C. Müller, M. Kaster, Â. R. Tomé, 2015, Proceedings of the National Academy of Sciences.

Treatment with A2A receptor antagonist KW6002 and caffeine intake regulate microglia reactivity and protect retina against transient ischemic damage

C. Müller, Â. R. Tomé, R. Cunha, 2017, Cell Death and Disease.

The VMAT-2 inhibitor tetrabenazine alters effort-related decision making as measured by the T-maze barrier choice task: reversal with the adenosine A2A antagonist MSX-3 and the catecholamine uptake blocker bupropion

J. Salamone, M. Correa, C. Müller, 2015, Psychopharmacology.

The vesicular monoamine transporter (VMAT-2) inhibitor tetrabenazine induces tremulous jaw movements in rodents: Implications for pharmacological models of parkinsonian tremor

J. Salamone, M. Correa, E. Nunes, 2013, Neuroscience.

Deep brain stimulation of the subthalamic nucleus reverses oral tremor in pharmacological models of parkinsonism: interaction with the effects of adenosine A2A antagonism

J. Salamone, C. Müller, S. Podurgiel, 2013, The European journal of neuroscience.

J. Salamone, M. Correa, C. Müller, 2014, Psychopharmacology.

The VMAT-2 Inhibitor Tetrabenazine Affects Effort-Related Decision Making in a Progressive Ratio/Chow Feeding Choice Task: Reversal with Antidepressant Drugs

J. Salamone, M. Correa, E. Nunes, 2014, PloS one.

J. Salamone, M. Correa, E. Nunes, 2013, The Journal of Neuroscience.

Tricyclic theophylline derivatives with high water-solubility: structure-activity relationships at adenosine receptors, phosphodiesterases, and benzodiazepine binding sites.

A. Drabczyńska, C. Müller, M. Pawłowski, 1995, Pharmazie.

Synthesis, biological activity and molecular modelling studies of tricyclic alkylimidazo-, pyrimido- and diazepinopurinediones

A. Drabczyńska, O. Yuzlenko, Meryem Köse, 2013, Purinergic Signalling.

Adenosine receptors in GtoPdb v.2021.2

B. Fredholm, K. Klotz, K. Jacobson, 2021, IUPHAR/BPS Guide to Pharmacology CITE.

Multigram-scale syntheses, stability, and photoreactions of A2A adenosine receptor antagonists with 8-styrylxanthine structure: potential drugs for Parkinson's disease.

C. Müller, J. Hockemeyer, J. Burbiel, 2004, The Journal of organic chemistry.

Effect of the adenosine A2A receptor antagonist MSX-3 on motivational disruptions of maternal behavior induced by dopamine antagonism in the early postpartum rat

J. Salamone, A. Farrar, C. Müller, 2010, Psychopharmacology.

Diabetes-induced Neuropathic Mechanical Hyperalgesia Depends on P2X4 Receptor Activation in Dorsal Root Ganglia

C. Müller, J. Figueiredo, C. Parada, 2019, Neuroscience.

The novel adenosine A2A antagonist prodrug MSX-4 is effective in animal models related to motivational and motor functions

J. Salamone, M. Correa, E. Nunes, 2012, Pharmacology Biochemistry and Behavior.

Dissection of P2X4 and P2X7 Receptor Current Components in BV-2 Microglia

C. Müller, G. Schmalzing, F. Markwardt, 2020, International journal of molecular sciences.

Bispidines for dual imaging.

C. Müller, P. Ceroni, P. Comba, 2014, Chemistry.

The platelet P2Y12 receptor under normal and pathological conditions. Assessment with the radiolabeled selective antagonist [3H]PSB-0413

C. Müller, C. Gachet, P. Ohlmann, 2013, Purinergic Signalling.

Caffeine modulates voluntary alcohol intake in mice depending on the access conditions: Involvement of adenosine receptors and the role of individual differences

J. Salamone, M. Correa, C. Müller, 2019, Pharmacology Biochemistry and Behavior.

Dual targeting of adenosine A(2A) receptors and monoamine oxidase B by 4H-3,1-benzothiazin-4-ones.

Sonja Hinz, Michael Gütschow, C. Müller, 2013, Journal of medicinal chemistry.

Effects of an adenosine A2A receptor blockade in the nucleus accumbens on locomotion, feeding, and prepulse inhibition in rats

W. Hauber, M. Koch, C. Müller, 2003, Synapse.

[(3)H]8-Ethyl-4-methyl-2-phenyl-(8R)-4,5,7,8-tetrahydro-1H-imidazo[2,1-i]-purin-5-one ([(3)H]PSB-11), a novel high-affinity antagonist radioligand for human A(3) adenosine receptors.

C. Müller, Christa E Müller, Mark Thorand, 2002, Bioorganic & medicinal chemistry letters.

A2A adenosine receptor antagonists - future drugs for Parkinson's disease?

C. Müller, 2000 .

BAY 60-6583 acts as a partial agonist at adenosine A 2 B receptors

C. Müller, Benjamin F. Seibt, Sonja Hinz, 2014 .

Tritium-labeled agonists as tools for studying adenosine A2B receptors

C. Müller, U. Pleiss, Sonja Hinz, 2018, Purinergic Signalling.

The adenosine A2A antagonist MSX-3 reverses the effort-related effects of dopamine blockade: differential interaction with D1 and D2 family antagonists

J. Salamone, A. Farrar, C. Müller, 2009, Psychopharmacology.

Adenosine A2A receptor antagonism reverses the effects of dopamine receptor antagonism on instrumental output and effort-related choice in the rat: implications for studies of psychomotor slowing

J. Salamone, A. Farrar, C. Müller, 2007, Psychopharmacology.

Dopaminergic Modulation of Effort-Related Choice Behavior as Assessed by a Progressive Ratio Chow Feeding Choice Task: Pharmacological Studies and the Role of Individual Differences

J. Salamone, M. Correa, E. Nunes, 2012, PloS one.

P2-pyrimidinergic receptors and their ligands.

C. Müller, 2002, Current pharmaceutical design.

Angiotensin II type 1/adenosine A2A receptor oligomers: a novel target for tardive dyskinesia

F. Ciruela, C. Müller, J. Giraldo, 2017, Scientific Reports.

The four cysteine residues in the second extracellular loop of the human adenosine A2B receptor: role in ligand binding and receptor function.

Farag F. Sherbiny, A. Schiedel, C. Müller, 2011, Biochemical pharmacology.

Role of P2 purinergic receptors in synaptic transmission under normoxic and ischaemic conditions in the CA1 region of rat hippocampal slices

C. Müller, F. Pedata, H. Stephan, 2007, Purinergic Signalling.

An agonist radioligand for the proinflammatory lipid-activated G protein-coupled receptor GPR84 providing structural insights.

Meryem Köse, C. Müller, I. von Kügelgen, 2019, Journal of medicinal chemistry.

Interactions between adenosine and dopamine receptor antagonists with different selectivity profiles: Effects on locomotor activity

Russell G. Port, J. Salamone, C. Müller, 2010, Behavioural Brain Research.

2‐Amino[1,2,4]triazolo[1,5‐c]quinazolines and Derived Novel Heterocycles: Syntheses and Structure–Activity Relationships of Potent Adenosine Receptor Antagonists

Meryem Köse, C. Müller, R. Kombu, 2016, ChemMedChem.

Inhibitors for the bacterial ectonucleotidase Lp1NTPDase from Legionella pneumophila.

C. Müller, E. Hartland, Amelie Fiene, 2016, Bioorganic & medicinal chemistry.

Medicinal chemistry of adenosine A3 receptor ligands.

C. Müller, 2003, Current topics in medicinal chemistry.

The adenosine A2A antagonist MSX-3 reverses the effects of the dopamine antagonist haloperidol on effort-related decision making in a T-maze cost/benefit procedure

Russell G. Port, J. Salamone, E. Nunes, 2009, Psychopharmacology.

Modulating P1 Adenosine Receptors in Disease Progression of SOD1G93A Mutant Mice

C. Müller, P. Popoli, R. Potenza, 2019, Neurochemical Research.

Microwave-assisted ring closure reactions: Synthesis of 8-substituted xanthine derivatives and related pyrimido- and diazepinopurinediones

C. Müller, J. Hockemeyer, J. Burbiel, 2006, Beilstein journal of organic chemistry.

Tricyclic oxazolo[2,3-f]purinediones: potency as adenosine receptor ligands and anticonvulsants.

A. Drabczyńska, C. Müller, K. Kieć‐Kononowicz, 2004, Bioorganic & medicinal chemistry.

8-Substituted 1,3-dimethyltetrahydropyrazino[2,1-f]purinediones: Water-soluble adenosine receptor antagonists and monoamine oxidase B inhibitors.

C. Müller, P. Koch, J. Heer, 2016, Bioorganic & medicinal chemistry.

Development of [(3)H]2-Carboxy-4,6-dichloro-1H-indole-3-propionic Acid ([(3)H]PSB-12150): A Useful Tool for Studying GPR17.

Meryem Köse, C. Müller, E. Kostenis, 2014, ACS medicinal chemistry letters.

1,3-Dialkyl-substituted tetrahydropyrimido[1,2-f]purine-2,4-diones as multiple target drugs for the potential treatment of neurodegenerative diseases.

A. Drabczyńska, Meryem Köse, C. Müller, 2013, Bioorganic & medicinal chemistry.

Injections of the selective adenosine A2A antagonist MSX-3 into the nucleus accumbens core attenuate the locomotor suppression induced by haloperidol in rats

J. Salamone, M. Correa, A. Farrar, 2007, Behavioural Brain Research.

Sensitive LC-MS/MS Method for the Quantification of Macrocyclic Gαq Protein Inhibitors in Biological Samples

C. Müller, B. Fleischmann, D. Wenzel, 2020, Frontiers in Chemistry.

Crystal structure of 3-benzyl-5,5-dimethylimidazolidine-2,4-dione, C12H14N2O2

C. Müller, N. Tzvetkov, B. Barbier, 2009 .

Coordination of capsule assembly and cell wall biosynthesis in Staphylococcus aureus

C. Müller, H. Sahl, M. Sylvester, 2019, Nature Communications.

Development of spin-labeled probes for adenosine receptors.

C. Müller, J. Ilaš, A. Kirfel, 2005, Journal of medicinal chemistry.

Methylxanthines block antigen-induced responses in RBL-2H3 cells independently of adenosine receptors or cyclic AMP: evidence for inhibition of antigen binding to IgE.

C. Müller, J. Daly, M. Beaven, 1991, The Journal of pharmacology and experimental therapeutics.

Tricyclic xanthine derivatives containing a basic substituent: adenosine receptor affinity and drug-related properties.

A. Drabczyńska, J. Handzlik, T. Karcz, 2018, MedChemComm.

A. Drabczyńska, Meryem Köse, J. Handzlik, 2016, Bioorganic & medicinal chemistry.

Pharmacological characterization of novel ligands of P2X3 receptor

C. Müller, 2017 .

Modeling ligand recognition at the P2Y12 receptor in light of X-ray structural information

Qiang Zhao, Stefano Moro, Christa E. Müller, 2015, Journal of Computer-Aided Molecular Design.

Medicinal chemistry of P2X receptors: allosteric modulators.

C. Müller, 2015, Current medicinal chemistry.

Emerging structures and ligands for P2X3 and P2X4 receptors—towards novel treatments of neuropathic pain

C. Müller, 2010, Purinergic Signalling.

3-(2-Carboxyethyl)indole-2-carboxylic Acid Derivatives: Structural Requirements and Properties of Potent Agonists of the Orphan G Protein-Coupled Receptor GPR17.

Meryem Köse, C. Müller, E. Kostenis, 2018, Journal of medicinal chemistry.

P2Y receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database

G. Burnstock, K. Jacobson, C. Müller, 2019, IUPHAR/BPS Guide to Pharmacology CITE.

Impact of the aryl substituent kind and distance from pyrimido[2,1-f]purindiones on the adenosine receptor selectivity and antagonistic properties.

A. Drabczyńska, C. Müller, K. Kieć‐Kononowicz, 2003, European journal of medicinal chemistry.

A new synthesis of sulfonamides by aminolysis of p-nitrophenylsulfonates yielding potent and selective adenosine A2B receptor antagonists.

K. Klotz, C. Müller, A. Hayallah, 2006, Journal of medicinal chemistry.

Novel multi-target directed ligands based on annelated xanthine scaffold with aromatic substituents acting on adenosine receptor and monoamine oxidase B. Synthesis, in vitro and in silico studies.

T. Karcz, K. Kuder, C. Müller, 2019, Bioorganic & medicinal chemistry.

Development of a microbioreactor with ecto-nucleoside triphosphate diphosphohydrolase 2 (NTPDase2) immobilized on a polyacrylamide-coated capillary at the outlet.

C. Müller, A. Knowles, J. Iqbal, 2010, Journal of chromatography. A.

P2Y2 receptor agonist with enhanced stability protects the heart from ischemic damage in vitro and in vivo

K. Jacobson, C. Müller, D. Aravot, 2013, Purinergic Signalling.

Quantification of green fluorescent protein-(GFP-) tagged membrane proteins by capillary gel electrophoresis.

C. Müller, Sang-Yong Lee, A. Danish, 2017, The Analyst.

Antiproliferative effects of selective adenosine receptor agonists and antagonists on human lymphocytes: evidence for receptor-independent mechanisms

A. Schiedel, C. Müller, P. Knolle, 2013, Purinergic Signalling Purinergic Signalling.

CD73 controls ocular adenosine levels and protects retina from light-induced phototoxicity

C. Müller, S. Jalkanen, G. Kalesnykas, 2021, Cellular and Molecular Life Sciences.

Synthesis of 8-Substituted Xanthine Derivatives by Suzuki Cross-Coupling Reaction

C. Müller, K. Vollmann, 2002 .

Anti-inflammatory effect of a novel locally acting A2A receptor agonist in a rat model of oxazolone-induced colitis

C. Müller, L. Ryskalin, Z. Nemeth, 2018, Purinergic Signalling.

J. Salamone, M. Correa, E. Nunes, 2013, Psychopharmacology.

Contribution of platelet P2Y12 receptors to chronic Complete Freund's adjuvant‐induced inflammatory pain

B. Sperlágh, C. Müller, Z. Környei, 2017, Journal of thrombosis and haemostasis : JTH.

Crystal structure of 4-bromobutyric acid 3-((4,4-difluoro-1,3,5,7-tetramethyl- 4-bora-3a,4a-diaza-s-indacen)-8-yl)propyl ester, C20H26BBrF2N2O2

C. Müller, A. Kirfel, H. Euler, 2002 .

Crystal structure of 8-(5-bromopentyl)-4,4-difluoro-1,3,5,7-tetramethyl- 4-bora-3a,4a-diaza-s-indacene, C18H24BBrF2N2

C. Müller, A. Kirfel, H. Euler, 2002 .

New developments in A1 and A2 adenosine receptor antagonists

H. Duddeck, A. Drabczyńska, C. Müller, 2001 .

CD39/ENTPD1 expression by CD4+Foxp3+ regulatory T cells promotes hepatic metastatic tumor growth in mice.

C. Müller, Wenda Gao, S. Robson, 2010, Gastroenterology.

Memory deficits induced by chronic cannabinoid exposure are prevented by adenosine A2AR receptor antagonism

A. Köfalvi, C. Müller, J. Ribeiro, 2019, Neuropharmacology.

Molecular and functional interaction between GPR18 and cannabinoid CB2 G‐protein‐coupled receptors. Relevance in neurodegenerative diseases

C. Müller, K. Kieć‐Kononowicz, R. Franco, 2018, Biochemical pharmacology.

Crystal structure of NTPDase2 in complex with the sulfoanthraquinone inhibitor PSB-071.

C. Müller, N. Sträter, M. Zebisch, 2014, Journal of structural biology.

Ecto-5′-Nucleotidase (CD73)-Mediated Formation of Adenosine Is Critical for the Striatal Adenosine A2A Receptor Functions

C. Müller, R. Cunha, J. Sévigny, 2013, The Journal of Neuroscience.

Antiproliferative effects of selective adenosine receptor agonists and antagonists on human lymphocytes: evidence for receptor-independent mechanisms

A. Schiedel, C. Müller, P. Knolle, 2013, Purinergic Signalling.

Adenosine A2A receptor contributes to the anti-inflammatory effect of the fixed herbal combination STW 5 (Iberogast®) in rat small intestinal preparations

C. Müller, O. Kelber, H. Abdel-Aziz, 2011, Naunyn-Schmiedeberg's Archives of Pharmacology.

Cardiac myocyte-secreted cAMP exerts paracrine action via adenosine receptor activation.

C. Müller, J. Hulot, T. Thum, 2014, The Journal of clinical investigation.

Extracellular NAD(+) induces a rise in [Ca(2+)](i) in activated human monocytes via engagement of P2Y(1) and P2Y(11) receptors.

C. Müller, S. Hauschildt, Carina Klein, 2009, Cell calcium.

Soluble and membrane-bound adenylate kinase and nucleotidases augment ATP-mediated inflammation in diabetic retinopathy eyes with vitreous hemorrhage

C. Müller, S. Jalkanen, K. Lehti, 2019, Journal of Molecular Medicine.

P2Y12 Receptor Localizes in the Renal Collecting Duct and Its Blockade Augments Arginine Vasopressin Action and Alleviates Nephrogenic Diabetes Insipidus.

C. Müller, D. Kohan, B. Kishore, 2015, Journal of the American Society of Nephrology : JASN.

Inhibition of phytohemagglutinine-induced T lymphocyte proliferation by 6-(octadecyldithio)purine, a novel liposomal prodrug of 6-mercaptopurine.

C. Müller, P. Daniel, H. Roth, 1989, Archives of toxicology. Supplement. = Archiv fur Toxikologie. Supplement.

Role of extracellular cysteine residues in the adenosine A2A receptor

A. Schiedel, C. Müller, V. Namasivayam, 2016, Purinergic Signalling.

Structure-activity relationships of flavonoids as inhibitors of breast cancer resistance protein (BCRP).

C. Müller, H. Bönisch, I. Pajeva, 2011, Bioorganic & medicinal chemistry.

Interaction of New, Very Potent Non-Nucleotide Antagonists with Arg256 of the Human Platelet P2Y12 Receptor

C. Müller, I. von Kügelgen, María Sol Morena, 2009, Journal of Pharmacology and Experimental Therapeutics.

Synthesis of uracil nucleotide analogs with a modified, acyclic ribose moiety as P2Y(2) receptor antagonists.

C. Müller, Marko Kaulich, A. El-Tayeb, 2009, Bioorganic & Medicinal Chemistry.

Improved synthesis of 4-/6-substituted 2-carboxy-1H-indole-3-propionic acid derivatives and structure–activity relationships as GPR17 agonists

C. Müller, E. Kostenis, Andreas Spinrath, 2014 .

Cellular Localization of P0 (Adenine) Receptor in Rat Kidney

C. Müller, B. Kishore, J. Peti-Peterdi, 2012 .