Sujata Sharma

发表

Discovery of pyrazolopyrimidine phosphodiesterase 10A inhibitors for the treatment of schizophrenia.

John D. Schreier, I. Raheem, J. Fuerst, 2016, Bioorganic & medicinal chemistry letters.

Identification of Shared Molecular Signatures Indicate the Susceptibility of Endometriosis to Multiple Sclerosis

Punit Kaur, Amit Katiyar, Sujata Sharma, 2018, Front. Genet..

Structural Studies on Molecular Interactions between Camel Peptidoglycan Recognition Protein, CPGRP-S, and Peptidoglycan Moieties N-Acetylglucosamine and N-Acetylmuramic Acid*

Sujata Sharma, T. Singh, P. Kaur, 2012, The Journal of Biological Chemistry.

Specific binding of non-steroidal anti-inflammatory drugs (NSAIDs) to phospholipase A2: structure of the complex formed between phospholipase A2 and diclofenac at 2.7 A resolution.

Sujata Sharma, T. Singh, S. Dey, 2006, Acta crystallographica. Section D, Biological crystallography.

Non-steroidal anti-inflammatory drugs as potent inhibitors of phospholipase A2: structure of the complex of phospholipase A2 with niflumic acid at 2.5 Angstroms resolution.

Sujata Sharma, T. Singh, S. Dey, 2005, Acta crystallographica. Section D, Biological crystallography.

Abstracts from the 3rd International Genomic Medicine Conference (3rd IGMC 2015)

Peter Natesan Pushparaj, Jennifer D. Churchill, Omran M. Rashidi, 2016, BMC Genomics.

Discovery of 1-amino-5H-pyrido[4,3-b]indol-4-carboxamide inhibitors of Janus kinase 2 (JAK2) for the treatment of myeloproliferative disorders.

Jongwon Lim, Michael D Altman, Craig Rosenstein, 2011, Journal of medicinal chemistry.

Crystal structure of GyrA intein from Mycobacterium xenopi reveals structural basis of protein splicing

Amalio Telenti, James C. Sacchettini, William R. Jacobs, 1998, Nature Structural Biology.

Structure Based In Silico Analysis of Quinolone Resistance in Clinical Isolates of Salmonella Typhi from India

M. Kumar, Sujata Sharma, T. Singh, 2015, PloS one.

Structure-based in-silico rational design of a selective peptide inhibitor for thymidine monophosphate kinase of mycobacterium tuberculosis

Sujata Sharma, T. Singh, P. Kaur, 2011, Journal of molecular modeling.

In silico identification of viper phospholipaseA2 inhibitors: validation by in vitro, in vivo studies

Sujata Sharma, A. Nargotra, G. N. Qazi, 2011, Journal of molecular modeling.

Interface peptide of Alzheimer's amyloid beta: application in purification.

Sujata Sharma, Munia Ganguli, T. Singh, 2007, Biochemical and biophysical research communications.

Mammalian Heme Peroxidases and Mycobacterium tuberculosis

Sujata Sharma, T. Singh, M. Sinha, 2012 .

Binding and structural studies of the complexes of type 1 ribosome inactivating protein from Momordica balsamina with uracil and uridine

Sujata Sharma, T. Singh, P. Kaur, 2019, Proteins.

Structural understanding of non-nucleoside inhibition in an elongating herpesvirus polymerase

A. W. Shaw, Mee Ra Heo, I. Raheem, 2021, Nature Communications.

Structural basis of activation of mammalian heme peroxidases.

Sujata Sharma, T. Singh, P. Kaur, 2017, Progress in Biophysics and Molecular Biology.

Lactoperoxidase: structural insights into the function,ligand binding and inhibition.

Sujata Sharma, T. Singh, P. Kaur, 2013, International journal of biochemistry and molecular biology.

Purification and characterization of a thermostable laccase from the ascomycetes Cladosporium cladosporioides and its applications

Sujata Sharma, T. Singh, T. Karegoudar, 2011 .

Structure of isocitrate lyase, a persistence factor of Mycobacterium tuberculosis

Sujata Sharma, J. Sacchettini, W. Jacobs, 2000, Nature Structural Biology.

Modulation of inhibitory activity of xylanase - α-amylase inhibitor protein (XAIP): binding studies and crystal structure determination of XAIP- II from Scadoxus multiflorus at 1.2 Å resolution

Sujata Sharma, T. Singh, P. Kaur, 2010, BMC Structural Biology.

Crystal structure determination and inhibition studies of a novel xylanase and α‐amylase inhibitor protein (XAIP) from Scadoxus multiflorus

Sujata Sharma, T. Singh, P. Kaur, 2010, The FEBS journal.

Group III PLA2 from the scorpion, Mesobuthus tamulus: cloning and recombinant expression in E. coli

Sujata Sharma, T. Singh, P. Kaur, 2009 .

Quantitative structure activity relationship (QSAR) of piperine analogs for bacterial NorA efflux pump inhibitors.

Sujata Sharma, A. Nargotra, Ashwani Kumar, 2009, European journal of medicinal chemistry.

In silico proteomic characterization of human epidermal growth factor receptor 2 (HER-2) for the mapping of high affinity antigenic determinants against breast cancer

Shishir K. Gupta, Sujata Sharma, B. A. Akhoon, 2012, Amino Acids.

Mechanism of action of the cell-division inhibitor PC190723: modulation of FtsZ assembly cooperativity.

Sujata Sharma, K. Lumb, S. Soisson, 2012, Journal of the American Chemical Society.

Structural and Functional Studies of Mammalian Peptidoglycan Recognition Protein, PGRP-S

Sujata Sharma, T. Singh, P. Kaur, 2014 .

Characterization of non-nitrocatechol pan and isoform specific catechol-O-methyltransferase inhibitors and substrates.

Scott T. Harrison, K. K. Nanda, Monika Kandebo, 2012, ACS chemical neuroscience.

Saponins as novel TNF-alpha inhibitors: isolation of saponins and a nor-pseudoguaianolide from Parthenium hysterophorus.

Sujata Sharma, S. C. Taneja, B. A. Shah, 2009, Organic & biomolecular chemistry.

Antimicrobial Lactoferrin Peptides: The Hidden Players in the Protective Function of a Multifunctional Protein

Sujata Sharma, T. Singh, P. Kaur, 2013, International journal of peptides.

Identification of an allosteric binding site for RORγt inhibition

C. Ottmann, Sujata Sharma, H. van Eenennaam, 2015, Nature Communications.

Crystal Structure of a Novel Regulatory 40-kDa Mammary Gland Protein (MGP-40) Secreted during Involution*

Sujata Sharma, T. Singh, P. Kaur, 2003, The Journal of Biological Chemistry.

From Screening to Targeted Degradation: Strategies for the Discovery and Optimization of Small Molecule Ligands for PCSK9.

Sujata Sharma, J. Lisnock, P. Orth, 2019, Cell chemical biology.

Lactoferrin and its nano-formulations in rare eye diseases

Sujata Sharma, T. Singh, P. Sharma, 2022, Indian journal of ophthalmology.

Expression, purification and crystallization of human prolylcarboxypeptidase.

Sujata Sharma, D. Hall, R. Diehl, 2010, Acta crystallographica. Section F, Structural biology and crystallization communications.

Structural Basis of Human p70 Ribosomal S6 Kinase-1 Regulation by Activation Loop Phosphorylation

Sujata Sharma, S. Munshi, D. Hall, 2009, The Journal of Biological Chemistry.

Structure of the Bacterial Deacetylase LpxC Bound to the Nucleotide Reaction Product Reveals Mechanisms of Oxyanion Stabilization and Proton Transfer

Sujata Sharma, D. Klein, K. Lumb, 2013, The Journal of Biological Chemistry.

Insights into activity and inhibition from the crystal structure of human O-GlcNAcase.

Sujata Sharma, D. Klein, D. Hall, 2017, Nature chemical biology.

Ligand recognition by peptidoglycan recognition protein-S (PGRP-S): structure of the complex of camel PGRP-S with heptanoic acid at 2.15 Å resolution.

Sujata Sharma, T. Singh, P. Kaur, 2022, International journal of biochemistry and molecular biology.

Structure of Yak Lactoperoxidase at 1.55 Å Resolution

Sujata Sharma, T. Singh, P. Kaur, 2021, The Protein Journal.

Biological Properties and Characterization of ASL50 Protein from Aged Allium sativum Bulbs

Sujata Sharma, T. Singh, S. Dey, 2015, Applied Biochemistry and Biotechnology.

Isolation, purification, crystallization and preliminary crystallographic studies of amaryllin, a plant pathogenesis-related protein from Amaryllis belladonna.

Sujata Sharma, T. Singh, P. Kaur, 2009, Acta crystallographica. Section F, Structural biology and crystallization communications.

Evidence of a novel allergenic protein Narcin in the bulbs of Narcissus tazetta.

Sujata Sharma, T. Singh, P. Kaur, 2013, International journal of biochemistry and molecular biology.

Transcriptional Silencing of a tRNA1Gly Copy from within a Multigene Family Is Modulated by Distal cis Elements*

Sujata Sharma, K. Gopinathan, 1996, The Journal of Biological Chemistry.

Crystal structure of the disintegrin heterodimer from saw-scaled viper (Echis carinatus) at 1.9 A resolution.

M. Perbandt, C. Betzel, Sujata Sharma, 2005, Biochemistry.

Discovery of tetrahydropyridopyrimidine phosphodiesterase 10A inhibitors for the treatment of schizophrenia.

John D. Schreier, I. Raheem, J. Fuerst, 2012, Bioorganic & medicinal chemistry letters.

Crystal structure of the complex of group I PLA2 with a group II-specific peptide Leu-Ala-Ile-Tyr-Ser (LAIYS) at 2.6 Å resolution

Sujata Sharma, T. Singh, S. Dey, 2005, Journal of drug targeting.

Abstracts from the 3rd International Genomic Medicine Conference (3rd IGMC 2015)

Peter Natesan Pushparaj, Jennifer D. Churchill, Omran M. Rashidi, 2016, BMC Genomics.

Structure of the complex of camel peptidoglycan recognition protein-S with hexanoic reveals novel features of the versatile ligand-binding site at the dimeric interface.

Sujata Sharma, T. Singh, P. Kaur, 2022, Biochimica et biophysica acta. Proteins and proteomics.

Potassium-induced partial inhibition of lactoperoxidase: structure of the complex of lactoperoxidase with potassium ion at 2.20 Å resolution

Sujata Sharma, T. Singh, P. Kaur, 2021, JBIC Journal of Biological Inorganic Chemistry.

C-Lobe of Lactoferrin: The Whole Story of the Half-Molecule

Sujata Sharma, T. Singh, P. Kaur, 2013, Biochemistry research international.

A glycoprotein from mammary gland secreted during involution promotes apoptosis: Structural and biological studies.

Sujata Sharma, T. Singh, P. Kaur, 2018, Archives of biochemistry and biophysics.

Carbohydrate binding properties and carbohydrate induced conformational switch in sheep secretory glycoprotein (SPS-40): crystal structures of four complexes of SPS-40 with chitin-like oligosaccharides.

Sharmistha Dey, Sujata Sharma, A. S. Ethayathulla, 2007, Journal of structural biology.

Carbohydrate-binding properties of goat secretory glycoprotein (SPG-40) and its functional implications: structures of the native glycoprotein and its four complexes with chitin-like oligosaccharides.

Punit Kaur, Sujata Sharma, A. S. Ethayathulla, 2007, Acta crystallographica. Section D, Biological crystallography.

Crystal structure of a secretory signalling glycoprotein from sheep at 2.0A resolution.

Sujata Sharma, A. S. Ethayathulla, T. Singh, 2006, Journal of structural biology.

Structural and binding studies of peptidyl-tRNA hydrolase from Pseudomonas aeruginosa provide a platform for the structure-based inhibitor design against peptidyl-tRNA hydrolase.

Punit Kaur, Sujata Sharma, T. Singh, 2014, The Biochemical journal.

Isolation and characterization of novel protein with anti-fungal and anti-inflammatory properties from Aloe vera leaf gel.

Sujata Sharma, T. Singh, S. Dey, 2011, International journal of biological macromolecules.

Current Perspectives in NSAID-Induced Gastropathy

Punit Kaur, Sujata Sharma, T. Singh, 2013, Mediators of inflammation.

Current Overview of Allergens of Plant Pathogenesis Related Protein Families

Sujata Sharma, T. Singh, P. Kaur, 2014, TheScientificWorldJournal.

3D-QSAR based pharmacophore modeling and virtual screening for identification of novel pteridine reductase inhibitors

Sujata Sharma, T. Singh, P. Kaur, 2012, Journal of Molecular Modeling.

Inhibition of Protein Aggregation: Supramolecular Assemblies of Arginine Hold the Key

Sujata Sharma, A. Verma, A. S. Ethayathulla, 2007, PloS one.

Enhancement of catalytic efficiency of enzymes through exposure to anhydrous organic solvent at 70°C. Three‐dimensional structure of a treated serine proteinase at 2.2 Å resolution

Sujata Sharma, M. N. Gupta, T. Singh, 2000, Proteins.

Structural Basis for the Inhibition of RNase H Activity of HIV-1 Reverse Transcriptase by RNase H Active Site-Directed Inhibitors

Christopher L. Daniels, D. Hazuda, Sujata Sharma, 2010, Journal of Virology.

Identification of bioactive molecule from Withania somnifera (Ashwagandha) as SARS-CoV-2 main protease inhibitor

Sujata Sharma, A. S. Ethayathulla, T. Singh, 2020, Journal of biomolecular structure & dynamics.

Crystal structure of lactoperoxidase at 2.4 A resolution.

Sujata Sharma, T. Singh, P. Kaur, 2007, Journal of molecular biology.

Overcoming resistance to checkpoint blockade therapy by targeting PI3Kγ in myeloid cells

J. Kutok, J. Wolchok, Sujata Sharma, 2016, Nature.

Enzymatic toxins from snake venom: structural characterization and mechanism of catalysis

C. Betzel, Sujata Sharma, R. Kini, 2011, The FEBS journal.

Iodide supplementation of the anti-viral duox-lactoperoxidase activity may prevent some SARS-CoV-2 infections

Sujata Sharma, T. Singh, Michael L. Smith, 2021, European Journal of Clinical Nutrition.

Structural evidence of the oxidation of iodide ion into hyper‐reactive hypoiodite ion by mammalian heme lactoperoxidase

Sujata Sharma, T. Singh, P. Sharma, 2021, Protein science : a publication of the Protein Society.

Bovine Carbonyl Lactoperoxidase Structure at 2.0Å Resolution and Infrared Spectra as a Function of pH

Sujata Sharma, T. Singh, P. Kaur, 2012, The Protein Journal.

Identification of potential drug candidates to combat COVID-19: a structural study using the main protease (mpro) of SARS-CoV-2

Sujata Sharma, T. Singh, P. Kaur, 2020, Journal of biomolecular structure & dynamics.

First structural evidence of sequestration of mRNA cap structures by type 1 ribosome inactivating protein from Momordica balsamina

Punit Kaur, Sujata Sharma, T. Singh, 2013, Proteins.

Crystal structures of a type-1 ribosome inactivating protein from Momordica balsamina in the bound and unbound states.

Punit Kaur, Sujata Sharma, T. Singh, 2012, Biochimica et biophysica acta.

A Peptide Bond from the Inter-lobe Segment in the Bilobal Lactoferrin Acts as a Preferred Site for Cleavage for Serine Proteases to Generate the Perfect C-lobe: Structure of the Pepsin Hydrolyzed Lactoferrin C-lobe at 2.28 Å Resolution

Sujata Sharma, T. Singh, P. Sharma, 2021, The Protein Journal.

Structure of iron saturated C‐lobe of bovine lactoferrin at pH 6.8 indicates a weakening of iron coordination

Sujata Sharma, T. Singh, P. Kaur, 2015, Proteins.

Piperine as an inhibitor of Rv1258c, a putative multidrug efflux pump of Mycobacterium tuberculosis.

M. Kumar, Sujata Sharma, A. Nargotra, 2010, The Journal of antimicrobial chemotherapy.

Computational Intelligence in Drug Repurposing for COVID-19

Manish Kumar Tripathi, Sujata Sharma, Tej P. Singh, 2020 .

Evolving transpeptidase and hydrolytic variants of γ-glutamyl transpeptidase from Bacillus licheniformis by targeted mutations of conserved residue Arg109 and their biotechnological relevance.

Sujata Sharma, T. Singh, Rani Gupta, 2017, Journal of biotechnology.

Genome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms.

Alexey Bochkarev, Wolfram Tempel, Anne Mulichak, 2007, Molecular and biochemical parasitology.

RASOnD - A comprehensive resource and search tool for RAS superfamily oncogenes from various species

Punit Kaur, Umay Kulsum, Sujata Sharma, 2011, BMC Genomics.

Structural definition and substrate specificity of the S28 protease family: the crystal structure of human prolylcarboxypeptidase

Sujata Sharma, D. Hall, R. Diehl, 2010, BMC Structural Biology.

Crystal structures of the complexes of a group IIA phospholipase A2 with two natural anti‐inflammatory agents, anisic acid, and atropine reveal a similar mode of binding

M. Perbandt, C. Betzel, Sujata Sharma, 2006, Proteins.

Codon optimization can improve expression of human genes in Escherichia coli: A multi-gene study.

Udo Oppermann, Frank Sobott, Opher Gileadi, 2008, Protein expression and purification.

The structural basis for the prevention of nonsteroidal antiinflammatory drug-induced gastrointestinal tract damage by the C-lobe of bovine colostrum lactoferrin.

Punit Kaur, Sujata Sharma, T. Singh, 2009, Biophysical journal.

TagA, a putative serine protease/ABC transporter of Dictyostelium that is required for cell fate determination at the onset of development

C. Shaw, G. Shaulsky, A. Kuspa, 2003, Development.

Specific interactions of C-terminal half (C-lobe) of lactoferrin protein with edible sugars: binding and structural studies with implications on diabetes.

Sujata Sharma, T. Singh, P. Kaur, 2010, International journal of biological macromolecules.

Enhancement of stability of a lipase by subjecting to three phase partitioning (TPP): structures of native and TPP-treated lipase from Thermomyces lanuginosa

Sujata Sharma, M. N. Gupta, T. Singh, 2015 .

Integration of Affinity Selection–Mass Spectrometry and Functional Cell-Based Assays to Rapidly Triage Druggable Target Space within the NF-κB Pathway

Patrick J. Curran, Sujata Sharma, I. Kariv, 2016, Journal of biomolecular screening.

Cloning, expression, crystallization and preliminary structural studies of dihydrodipicolinate reductase from Acinetobacter baumannii.

Sujata Sharma, T. Singh, P. Kaur, 2013, Acta crystallographica. Section F, Structural biology and crystallization communications.

New Weapons in the War on Tuberculosis

M. Yoder, Sujata Sharma, 2011, American journal of therapeutics.

Biochemical studies and crystal structure determination of dihydrodipicolinate synthase from Pseudomonas aeruginosa.

Rohit K. Sharma, Sujata Sharma, T. Singh, 2010, International journal of biological macromolecules.

Preparation and Antimicrobial Action of Three Tryptic Digested Functional Molecules of Bovine Lactoferrin

J. S. Virdi, Sujata Sharma, T. Singh, 2014, PloS one.

Identification of promising drug candidates against NSP16 of SARS-CoV-2 through computational drug repurposing study

Sujata Sharma, T. Singh, P. Kaur, 2020, Journal of biomolecular structure & dynamics.

Structural Evidence of Substrate Specificity in Mammalian Peroxidases

Sujata Sharma, T. Singh, P. Kaur, 2009, Journal of Biological Chemistry.

Structure of chitinase D from Serratia proteamaculans reveals the structural basis of its dual action of hydrolysis and transglycosylation.

Sujata Sharma, T. Singh, P. Kaur, 2013, International journal of biochemistry and molecular biology.

Structure of bovine lactoperoxidase with a partially linked heme moiety at 1.98Å resolution.

Sujata Sharma, T. Singh, P. Kaur, 2017, Biochimica et biophysica acta. Proteins and proteomics.

Structural Basis of Recognition of Pathogen-associated Molecular Patterns and Inhibition of Proinflammatory Cytokines by Camel Peptidoglycan Recognition Protein*

Sujata Sharma, T. Singh, P. Kaur, 2011, The Journal of Biological Chemistry.

Identification of a high affinity selective inhibitor of Polo-like kinase 1 for cancer chemotherapy by computational approach.

M. Kumar, Sujata Sharma, T. Singh, 2014, Journal of molecular graphics & modelling.

Structures and binding studies of the complexes of phospholipase A2 with five inhibitors.

Sujata Sharma, T. Singh, P. Kaur, 2015, Biochimica et biophysica acta.

In silico proteomic characterization of human epidermal growth factor receptor 2 (HER-2) for the mapping of high affinity antigenic determinants against breast cancer

Shishir K. Gupta, Sujata Sharma, B. A. Akhoon, 2012, Amino Acids.

Crystal structure of schistatin, a disintegrin homodimer from saw-scaled viper (Echis carinatus) at 2.5 A resolution.

Sujata Sharma, T. Singh, P. Kaur, 2004, Journal of molecular biology.

Structural Insights into the Dual Strategy of Recognition by Peptidoglycan Recognition Protein, PGRP-S: Structure of the Ternary Complex of PGRP-S with Lipopolysaccharide and Stearic Acid

Sujata Sharma, T. Singh, P. Kaur, 2013, PloS one.

Structural basis of the binding of fatty acids to peptidoglycan recognition protein, PGRP-S through second binding site.

Sujata Sharma, T. Singh, P. Kaur, 2013, Archives of biochemistry and biophysics.

Structural basis of heparin binding to camel peptidoglycan recognition protein-S.

Sujata Sharma, T. Singh, P. Kaur, 2010, International journal of biochemistry and molecular biology.

Multiligand Specificity of Pathogen-associated Molecular Pattern-binding Site in Peptidoglycan Recognition Protein*

Sujata Sharma, T. Singh, P. Kaur, 2011, The Journal of Biological Chemistry.

Crystal structure of the peptidoglycan recognition protein at 1.8 A resolution reveals dual strategy to combat infection through two independent functional homodimers.

M. Perbandt, C. Betzel, Sujata Sharma, 2008, Journal of molecular biology.

Detection of native peptides as potent inhibitors of enzymes

C. Betzel, Sujata Sharma, M. N. Gupta, 2005, The FEBS journal.

Structure and binding studies of proliferating cell nuclear antigen from Leishmania donovani.

Sujata Sharma, T. Singh, P. Kaur, 2017, Biochimica et biophysica acta. Proteins and proteomics.

Aspirin induces its anti-inflammatory effects through its specific binding to phospholipase A2: Crystal structure of the complex formed between phospholipase A2 and aspirin at 1.9 Å resolution

Punit Kaur, Sujata Sharma, A. S. Ethayathulla, 2004, Journal of drug targeting.

Phosphopantetheine Adenylyltransferase: A promising drug target to combat antibiotic resistance.

Sujata Sharma, T. Singh, P. Sharma, 2020, Biochimica et biophysica acta. Proteins and proteomics.

Structural and functional insights into peptidyl-tRNA hydrolase.

Sujata Sharma, T. Singh, P. Kaur, 2014, Biochimica et biophysica acta.

In-vitro Characterization and Purification of Bacteriocins Isolated from Probiotic Curd Culture

Sujata Sharma, Arora Saahil, S. Vashist, 2021, Journal of Pharmaceutical Research International.

Crystal structure of human seminal diferric lactoferrin at 3.4 Å resolution

C. Betzel, Sujata Sharma, T. Singh, 2003 .

Discovery of the Lead Molecules Targeting the First Step of the Histidine Biosynthesis Pathway of Acinetobacter baumannii

Sujata Sharma, T. Singh, P. Sharma, 2022, J. Chem. Inf. Model..

Structure prediction and discovery of inhibitors against phosphopantothenoyl cysteine synthetase of Acinetobacter baumannii

Sujata Sharma, T. Singh, P. Kaur, 2021, Journal of biomolecular structure & dynamics.

Lactosmart: A Novel Therapeutic Molecule for Antimicrobial Defense

Sujata Sharma, T. Singh, P. Sharma, 2021, Frontiers in Microbiology.

Structure-Based Virtual Screening and Biochemical Validation to Discover a Potential Inhibitor of the SARS-CoV-2 Main Protease

Sujata Sharma, T. Singh, P. Kaur, 2020, ACS omega.

Sequence-induced trimerization of phospholipase A2: structure of a trimeric isoform of PLA2 from common krait (Bungarus caeruleus) at 2.5 A resolution.

C. Betzel, Sujata Sharma, T. Singh, 2005, Acta crystallographica. Section F, Structural biology and crystallization communications.

Structural elements of ligand recognition site in secretory phospho-lipase A2 and structure-based design of specific inhibitors.

Sujata Sharma, T. Singh, P. Kaur, 2007, Current topics in medicinal chemistry.

Crystal structure of a carbohydrate induced homodimer of phospholipase A2 from Bungarus caeruleus at 2.1A resolution.

C. Betzel, Sujata Sharma, T. Singh, 2004, Journal of structural biology.

Structure‐Based In silico Design of aHigh‐Affinity Dipeptide Inhibitor for Novel Protein Drug Target Shikimate Kinase of Mycobacterium tuberculosis

Punit Kaur, Shikha Verma, Sujata Sharma, 2010, Chemical biology & drug design.

Crystal structure of peptidyl-tRNA hydrolase from a Gram-positive bacterium, Streptococcus pyogenes at 2.19 Å resolution shows the closed structure of the substrate-binding cleft

Sujata Sharma, T. Singh, P. Kaur, 2014, FEBS open bio.

Crystal structure of peptidyl-tRNA hydrolase from mycobacterium smegmatis reveals novel features related to enzyme dynamics.

Sujata Sharma, T. Singh, N. Singh, 2012, International journal of biochemistry and molecular biology.

Crystal structure of a heterodimer of phospholipase A2 from Naja naja sagittifera at 2.3 Å resolution reveals the presence of a new PLA2‐like protein with a novel cys 32–Cys 49 disulphide bridge with a bound sugar at the substrate‐binding site

Sujata Sharma, T. Singh, P. Kaur, 2005, Proteins.

Structure of the zinc-saturated C-terminal lobe of bovine lactoferrin at 2.0 A resolution.

Sujata Sharma, T. Singh, N. Singh, 2005, Acta crystallographica. Section D, Biological crystallography.

Crystal structure of a proteolytically generated functional monoferric C-lobe of bovine lactoferrin at 1.9A resolution.

Sujata Sharma, T. Singh, J. Jasti, 2003, Journal of molecular biology.

Structure of the novel 14kDa fragment of alpha-subunit of phycoerythrin from the starving cyanobacterium Phormidium tenue.

Sujata Sharma, N. Singh, A. S. Ethayathulla, 2010, Journal of structural biology.

Structural basis for the cooperative allosteric activation of the free fatty acid receptor GPR40

Sujata Sharma, G. Bricogne, C. Vonrhein, 2017, Nature Structural &Molecular Biology.

Structural Basis for Selectivity and Diversity in Angiotensin II Receptors

M. Rudd, R. Stevens, M. Hunter, 2017, Nature.

Attenuation of scratch‐induced reactive astrogliosis by novel EphA4 kinase inhibitors

Sujata Sharma, Hemaka A. Rajapakse, J. Vacca, 2011, Journal of neurochemistry.

The Mode of Inhibitor Binding to Peptidyl-tRNA Hydrolase: Binding Studies and Structure Determination of Unbound and Bound Peptidyl-tRNA Hydrolase from Acinetobacter baumannii

Sujata Sharma, T. Singh, P. Kaur, 2013, PloS one.

Synthesis and Evaluation of Heterocyclic Catechol Mimics as Inhibitors of Catechol-O-methyltransferase (COMT).

Scott T. Harrison, Sujata Sharma, J. Barrow, 2015, ACS medicinal chemistry letters.

Crystal structure of a highly acidic neurotoxin from scorpion Buthus tamulus at 2.2A resolution reveals novel structural features.

Sujata Sharma, A. S. Ethayathulla, T. Singh, 2006, Journal of structural biology.

Crystal structure of a novel phospholipase A2 from Naja naja sagittifera with a strong anticoagulant activity.

Sujata Sharma, A. S. Ethayathulla, T. Singh, 2005, Toxicon : official journal of the International Society on Toxinology.

Polysaccharide binding sites in hyaluronate lyase – crystal structures of native phage–encoded hyaluronate lyase and its complexes with ascorbic acid and lactose

Christian Betzel, Punit Kaur, M. Perbandt, 2009, The FEBS journal.

Structure of a ternary complex of lactoperoxidase with iodide and hydrogen peroxide at 1.77 Å resolution.

Sujata Sharma, T. Singh, P. Kaur, 2021, Journal of inorganic biochemistry.

First structural evidence for the mode of diffusion of aromatic ligands and ligand-induced closure of the hydrophobic channel in heme peroxidases

Sujata Sharma, A. Tiwari, T. Singh, 2010, JBIC Journal of Biological Inorganic Chemistry.

Inhibition of lactoperoxidase by its own catalytic product: crystal structure of the hypothiocyanate-inhibited bovine lactoperoxidase at 2.3-A resolution.

Sujata Sharma, T. Singh, P. Kaur, 2009, Biophysical journal.

Structure of the iron‐free true C‐terminal half of bovine lactoferrin produced by tryptic digestion and its functional significance in the gut

Sujata Sharma, T. Singh, P. Kaur, 2014, The FEBS journal.

Structural and binding studies of C-terminal half (C-lobe) of lactoferrin protein with COX-2-specific non-steroidal anti-inflammatory drugs (NSAIDs).

Sujata Sharma, T. Singh, P. Kaur, 2010, Archives of biochemistry and biophysics.

Crystal structure of human seminal diferric lactoferrin at 3.4 Angstrom resolution.

C. Betzel, Sujata Sharma, T. Singh, 2003, Indian Journal of Biochemistry & Biophysics.

Crystal structure of a complex formed between proteolytically‐generated lactoferrin fragment and proteinase K

C. Betzel, Sujata Sharma, T. Singh, 1998, Proteins.

Phospholipase A2 as a target protein for nonsteroidal anti-inflammatory drugs (NSAIDS): crystal structure of the complex formed between phospholipase A2 and oxyphenbutazone at 1.6 A resolution.

Sharmistha Dey, Sujata Sharma, T. Singh, 2004, Biochemistry.

Discovery of a Distinct Chemical and Mechanistic Class of Allosteric HIV-1 Integrase Inhibitors with Antiretroviral Activity.

Mee Ra Heo, Min Xu, Sujata Sharma, 2017, ACS chemical biology.

Mode of Binding of the Tuberculosis Prodrug Isoniazid to Heme Peroxidases

Sujata Sharma, T. Singh, P. Kaur, 2009, The Journal of Biological Chemistry.

The identification of a novel lead class for phosphodiesterase 2 inhibition by fragment-based drug design.

Deping Wang, Sujata Sharma, W. Shipe, 2017, Bioorganic & medicinal chemistry letters.

Experimental techniques to study protein dynamics and conformations

Sujata Sharma, T. Singh, P. Sharma, 2022, Advances in Protein Molecular and Structural Biology Methods.

Structural studies on molecular interactions between camel peptidoglycan recognition protein, CPGRP-S, and peptidoglycan moieties N-acetylglucosamine and N-acetylmuramic acid.

Sujata Sharma, T. Singh, P. Kaur, 2014, The Journal of Biological Chemistry.

Binding Modes of Aromatic Ligands to Mammalian Heme Peroxidases with Associated Functional Implications

Sujata Sharma, T. Singh, P. Kaur, 2009, The Journal of Biological Chemistry.

Structure of the buffalo secretory signalling glycoprotein at 2.8 A resolution.

Sujata Sharma, A. S. Ethayathulla, T. Singh, 2007, Acta crystallographica. Section F, Structural biology and crystallization communications.

Structure of the zinc-induced heterodimer of two calcium-free isoforms of phospholipase A2 from Naja naja sagittifera at 2.7 angstroms resolution.

Sujata Sharma, T. Singh, N. Singh, 2005, Acta crystallographica. Section D, Biological crystallography.

Design of specific peptide inhibitors for group I phospholipase A2: structure of a complex formed between phospholipase A2 from Naja naja sagittifera (group I) and a designed peptide inhibitor Val-Ala-Phe-Arg-Ser (VAFRS) at 1.9 A resolution reveals unique features.

Sujata Sharma, T. Singh, P. Kaur, 2003, Biochemistry.

Structural evidence for the order of preference of inorganic substrates in mammalian heme peroxidases: crystal structure of the complex of lactoperoxidase with four inorganic substrates, SCN, I, Br and Cl.

Sujata Sharma, T. Singh, P. Kaur, 2011, International journal of biochemistry and molecular biology.

Structure of a bovine secretory signalling glycoprotein (SPC-40) at 2.1 Angstrom resolution.

Sujata Sharma, A. S. Ethayathulla, T. Singh, 2006, Acta crystallographica. Section D, Biological crystallography.

Comments on the Discussion Forum: Oromucosal immunomodulation as clinical spectrum mitigating factor in SARS‐CoV‐2 infection

Sujata Sharma, T. Singh, Michael L. Smith, 2021, Scandinavian journal of immunology.

Potassium-induced partial inhibition of lactoperoxidase: structure of the complex of lactoperoxidase with potassium ion at 2.20 Å resolution

Sujata Sharma, T. Singh, P. Kaur, 2021, Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry.

Design of anti‐thyroid drugs: Binding studies and structure determination of the complex of lactoperoxidase with 2‐mercaptoimidazole at 2.30 Å resolution

Sujata Sharma, T. Singh, P. Kaur, 2017, Proteins.

Dual binding mode of antithyroid drug methimazole to mammalian heme peroxidases – structural determination of the lactoperoxidase–methimazole complex at 1.97 Å resolution

Sujata Sharma, T. Singh, P. Kaur, 2016, FEBS open bio.

Search of multiple hot spots on the surface of peptidyl-tRNA hydrolase: structural, binding and antibacterial studies.

Sujata Sharma, T. Singh, P. Kaur, 2018, The Biochemical journal.

Nanoformulation approach for improved antimicrobial activity of bovine lactoperoxidase

Sujata Sharma, P. Sharma, Anamika Singh, 2022, Journal of Dairy Research.

Isolation, purification, crystallization and preliminary crystallographic studies of sagitoxin, an oligomeric cardiotoxin from the venom of Naja naja saggitifera.

Sujata Sharma, T. Singh, P. Kaur, 2008, Acta crystallographica. Section F, Structural biology and crystallization communications.

Cloning, Expression, and Purification of Nucleoside Diphosphate Kinase from Acinetobacter baumannii

Sujata Sharma, T. Singh, P. Kaur, 2013, Enzyme research.

Effect of conservative mutations (L94V and L94I) on the structure and stability of horse cytochrome c.

Sujata Sharma, F. Ahmad, T. Singh, 2017, Archives of biochemistry and biophysics.

Pharmacophore Mapping, In Silico Screening and Molecular Docking to Identify Selective Trypanosoma brucei Pteridine Reductase Inhibitors

Sujata Sharma, T. Singh, P. Kaur, 2014, Molecular informatics.

High dietary iodine intake may contribute to the low death rate from COVID‐19 infection in Japan with activation by the lactoperoxidase system

Sujata Sharma, T. Singh, Michael L. Smith, 2023, Scandinavian Journal of Immunology.

Crystallography based structure elucidation of the complex of C-terminal fragment of Aβ polypeptide of Alzheimer’s disease with phospholipase A2

Sujata Sharma, T. Singh, P. Kaur, 2014, BMC Genomics.

Crystallography based structure elucidation of the complex of C-terminal fragment of Aβ polypeptide of Alzheimer’s disease with phospholipase A2

Sujata Sharma, T. Singh, P. Kaur, 2014, BMC Genomics.

Discovery of arylsulfonamides as a novel class of allosteric integrase inhibitors with antiviral activity.

Adam R. Johnson, Sujata Sharma, D. Klein, 2023, Bioorganic & medicinal chemistry letters.

Crystal structure of the complex formed between a group I Phospholipase A2 and a naturally occurring fatty acid at 2.7 Å resolution

Sujata Sharma, T. Singh, P. Kaur, 2005, Protein science : a publication of the Protein Society.

Simultaneous inhibition of anti‐coagulation and inflammation: crystal structure of phospholipase A2 complexed with indomethacin at 1.4 Å resolution reveals the presence of the new common ligand‐binding site

Sujata Sharma, T. Singh, P. Kaur, 2009, Journal of molecular recognition : JMR.

Enzymatic toxins from snake venom: structural characterization and mechanism of catalysis

C. Betzel, Sujata Sharma, R. Kini, 2011, The FEBS journal.

Discovery of tetrahydropyridopyrimidine phosphodiesterase 10A inhibitors for the treatment of schizophrenia.

John D. Schreier, I. Raheem, J. Fuerst, 2012, Bioorganic & medicinal chemistry letters.

Binding and structural studies of the complexes of type 1 ribosome inactivating protein from Momordica balsamina with cytosine, cytidine, and cytidine diphosphate

Punit Kaur, Sujata Sharma, P. Kaur, 2015, Biochemistry and biophysics reports.

Structural Evidence of Substrate Specificity in Mammalian Peroxidases

Sujata Sharma, P. Kaur, M. Sinha, 2009, Journal of Biological Chemistry.

Biochemical studies and crystal structure determination of dihydrodipicolinate synthase from Pseudomonas aeruginosa.

Rohit K. Sharma, Sujata Sharma, T. Singh, 2010, International journal of biological macromolecules.

Structural Studies on Molecular Interactions between Camel Peptidoglycan Recognition Protein, CPGRP-S, and Peptidoglycan Moieties N-Acetylglucosamine and N-Acetylmuramic Acid*

Sujata Sharma, T. Singh, P. Kaur, 2012, The Journal of Biological Chemistry.

Search of multiple hot spots on the surface of peptidyl-tRNA hydrolase: structural, binding and antibacterial studies.

Sujata Sharma, T. Singh, P. Kaur, 2018, The Biochemical journal.

From Screening to Targeted Degradation: Strategies for the Discovery and Optimization of Small Molecule Ligands for PCSK9.

Sujata Sharma, P. Orth, J. Shipman, 2021, Cell chemical biology.

Structural Basis of Human p70 Ribosomal S6 Kinase-1 Regulation by Activation Loop Phosphorylation

Sujata Sharma, S. Munshi, D. Hall, 2009, The Journal of Biological Chemistry.

Sequence-induced trimerization of phospholipase A2: structure of a trimeric isoform of PLA2 from common krait (Bungarus caeruleus) at 2.5 A resolution.

C. Betzel, Sujata Sharma, T. Singh, 2005, Acta crystallographica. Section F, Structural biology and crystallization communications.

Integration of Affinity Selection–Mass Spectrometry and Functional Cell-Based Assays to Rapidly Triage Druggable Target Space within the NF-κB Pathway

Patrick J. Curran, Sujata Sharma, I. Kariv, 2016, Journal of biomolecular screening.

Structure of iron saturated C‐lobe of bovine lactoferrin at pH 6.8 indicates a weakening of iron coordination

Sujata Sharma, T. Singh, P. Kaur, 2015, Proteins.