Brian Rady

发表

Discovery of novel potent imidazo[1,2-b]pyridazine PDE10a inhibitors.

S. Meegalla, Hui-Sheng Huang, C. Illig, 2016, Bioorganic & medicinal chemistry letters.

Overexpression of E2F3 promotes proliferation of functional human β cells without induction of apoptosis

Q. Wang, Brian Rady, J. Oberholzer, 2013, Cell cycle.

Discovery of a GPR40 Superagonist: The Impact of Aryl Propionic Acid α-Fluorination.

S. Meegalla, Hui-Sheng Huang, Brian Rady, 2018, ACS medicinal chemistry letters.

PNPLA3 downregulation exacerbates the fibrotic response in human hepatic stellate cells

D. Brenner, M. Erion, Brian Rady, 2021, PloS one.

Use of Glucagon-Like Peptide-1 Agonists to Improve Islet Graft Performance

Brian Rady, Yong Wang, J. Oberholzer, 2013, Current Diabetes Reports.

Persistent or Transient Human β Cell Dysfunction Induced by Metabolic Stress: Specific Signatures and Shared Gene Expression with Type 2 Diabetes.

U. Boggi, G. Rutter, P. Froguel, 2020, Cell reports.

GPR40-Mediated Gα12 Activation by Allosteric Full Agonists Highly Efficacious at Potentiating Glucose-Stimulated Insulin Secretion in Human Islets

Brian Rady, M. Player, Shuyuan Zhao, 2018, Molecular Pharmacology.

Discovery of novel benzo[b]thiophene tetrazoles as non-carboxylate GPR40 agonists.

S. Meegalla, Hui-Sheng Huang, Brian Rady, 2017, Bioorganic & medicinal chemistry letters.

A FFAR1 full agonist restores islet function in models of impaired glucose-stimulated insulin secretion and diabetic non-human primates

Brian Rady, M. Player, L. Norquay, 2022, Frontiers in Endocrinology.

Overexpression of E2F3 promotes proliferation of functional human β cells without induction of apoptosis

Brian Rady, J. Oberholzer, P. Salmon, 2013, Cell cycle.