A. Bortolato

发表

Controlling the Dissociation of Ligands from the Adenosine A2A Receptor through Modulation of Salt Bridge Strength.

A. IJzerman, E. Segala, D. Guo, 2016, Journal of medicinal chemistry.

Unifying family A GPCR theories of activation.

Benjamin G Tehan, Andrea Bortolato, Jonathan S Mason, 2014, Pharmacology & therapeutics.

Generic GPCR residue numbers - aligning topology maps while minding the gaps.

Chris de Graaf, Stefan Mordalski, Vignir Isberg, 2015, Trends in pharmacological sciences.

Coumarin as attractive casein kinase 2 (CK2) inhibitor scaffold: an integrate approach to elucidate the putative binding motif and explain structure-activity relationships.

E. Uriarte, S. Moro, A. Bortolato, 2008, Journal of medicinal chemistry.

Designing a ligand for pharmaceutical purposes

Stefano Moro, Andrea Bortolato, S. Moro, 2008, Expert opinion on drug discovery.

Modeling and Design for Membrane Protein Targets

M. Congreve, A. Bortolato, R. Cooke, 2017 .

Impact of Recently Determined Crystallographic Structures of GPCRs on Drug Discovery

J. Mason, A. Bortolato, F. Deflorian, 2020 .

Carbazole-containing arylcarboxamides as BACE1 inhibitors.

S. Moro, J. Mason, A. Bortolato, 2011, Bioorganic & medicinal chemistry letters.

Molecular Dynamics Applications to GPCR Ligand Design

S. Moro, J. Mason, A. Bortolato, 2018, Biomolecular Simulations in Structure-Based Drug Discovery.

Methodologies for the Examination of Water in GPCRs.

J. Mason, A. Bortolato, B. Tehan, 2018, Methods in molecular biology.

Identification of Ligand Binding Hot Spots of the Histamine H1 Receptor following Structure-Based Fragment Optimization.

I. D. de Esch, R. Leurs, J. Mason, 2016, Journal of medicinal chemistry.

Perioperative benefit and outcome of thoracic epidural in esophageal surgery: a clinical review.

A. Bortolato, A. Ruol, S. Merigliano, 2018, Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus.

Early circulatory complications in liver transplant patients.

A. Bortolato, C. Carollo, U. Cillo, 2019, Transplantation reviews.

Competitive Binding of Ozanimod and Other Sphingosine 1-Phosphate Receptor Modulators at Receptor Subtypes 1 and 5

A. Bortolato, R. Hargreaves, J. Selkirk, 2022, Frontiers in Pharmacology.

New insights from structural biology into the druggability of G protein-coupled receptors.

Andrea Bortolato, Miles Congreve, Jonathan S Mason, 2012, Trends in pharmacological sciences.

Insights into the structure of class B GPCRs.

Chris de Graaf, Ming-Wei Wang, Andrea Bortolato, 2014, Trends in pharmacological sciences.

Reaction-Based Enumeration, Active Learning, and Free Energy Calculations To Rapidly Explore Synthetically Tractable Chemical Space and Optimize Potency of Cyclin-Dependent Kinase 2 Inhibitors

Markus K. Dahlgren, Ivan Tubert Brohman, A. Bortolato, 2019, J. Chem. Inf. Model..

Continuous stellate ganglion block in delayed cerebral ischemia: A possible supplementary approach to traditional therapy?

A. Bortolato, M. Munari, P. Feltracco, 2020, Journal of anaesthesiology, clinical pharmacology.

Extra-helical binding site of a glucagon receptor antagonist

S. P. Andrews, A. Bortolato, A. Doré, 2016, Nature.

Mechanical thrombectomy in a pediatric patient with sedation aided by contralateral intra-arterial propofol injection: feasibility in an extreme condition

A. Bortolato, F. Causin, M. Munari, 2020, Child's Nervous System.

Structure of class B GPCR corticotropin-releasing factor receptor 1

Ali Jazayeri, Andrea Bortolato, Malcolm Weir, 2013, Nature.

Probabilistic Determination of Consumers Response and Consumption Management Strategies in Demand Response Programs

A. Bortolato, Z. Vale, P. Faria, 2020, 2020 IEEE/PES Transmission and Distribution Conference and Exposition (T&D).

α‐Naphthylaminopropan‐2‐ol Derivatives as BACE1 Inhibitors

Marco Macchia, Andrea Bortolato, Carlotta Granchi, 2008, ChemMedChem.

The perils of dental vacation: possible anaesthetic and medicolegal consequences

A. Bortolato, C. Ori, T. Tonetti, 2013, Medicine, science, and the law.

Activated recombinant protein C in septic shock early after liver transplantation: a case report.

A. Bortolato, C. Ori, P. Feltracco, 2008, Transplantation proceedings.

The ATP‐Binding Site of Protein Kinase CK2 Holds a Positive Electrostatic Area and Conserved Water Molecules

S. Moro, A. Bortolato, L. Cendron, 2007, Chembiochem : a European journal of chemical biology.

ATP non-competitive Ser/Thr kinase inhibitors as potential anticancer agents.

S. Moro, A. Bortolato, G. Cozza, 2009, Anti-cancer agents in medicinal chemistry.

How druggable is protein kinase CK2?

S. Moro, A. Bortolato, G. Cozza, 2010, Medicinal research reviews.

Rational design of new protein kinases inhibitors of pharmaceutical interest

A. Bortolato, 2008 .

Greater Occipital Nerve Block as a Tool to Diagnose Spontaneous Intracranial Hypotension Before Epidural Blood Patch: A Case Report.

A. Bortolato, F. Causin, G. Cester, 2019, A&A practice.

Ropivacaine versus levobupivacaine for minor breast surgery in outpatients: inversion of postoperative pain relief efficacy.

A. Bortolato, F. Lumachi, M. Marchesini, 2012, In vivo.

Transient abdominal motor block after a transversus abdominis plane block in an elderly patient

A. Bortolato, U. Freo, C. Ori, 2015, Canadian Journal of Anesthesia/Journal canadien d'anesthésie.

Water Network Perturbation in Ligand Binding: Adenosine A2A Antagonists as a Case Study

Jonathan W. Essex, Michael S. Bodnarchuk, Jonathan S. Mason, 2013, J. Chem. Inf. Model..

Impact of protein–ligand solvation and desolvation on transition state thermodynamic properties of adenosine A2A ligand binding kinetics

Francesca Deflorian, Andrea Bortolato, Stephanie Federico, 2017, In Silico Pharmacology.

Conformational thermostabilisation of corticotropin releasing factor receptor 1

A. Bortolato, F. Marshall, A. Jazayeri, 2015, Scientific Reports.

On Ternary Complex Stability in Protein Degradation: In Silico Molecular Glue Binding Affinity Calculations

Dahlia R. Weiss, A. Bortolato, V. Shanmugasundaram, 2023, J. Chem. Inf. Model..

Structure of Class B GPCRs: new horizons for drug discovery

Benjamin G Tehan, Andrea Bortolato, Andrew S Doré, 2014, British journal of pharmacology.

Crystal structure of the GLP-1 receptor bound to a peptide agonist

Ali Jazayeri, Jonathan S. Mason, Andrea Bortolato, 2017, Nature.

Progress in elucidating the structural and dynamic character of G Protein-Coupled Receptor oligomers for use in drug discovery.

D Provasi, A. Bortolato, M. Filizola, 2009, Current pharmaceutical design.

Deconstructing the Pharmacological Contribution of Sphingosine-1 Phosphate Receptors to Mouse Models of Multiple Sclerosis Using the Species Selectivity of Ozanimod, a Dual Modulator of Human Sphingosine 1-Phosphate Receptor Subtypes 1 and 5

A. Bortolato, R. Hargreaves, D. Dalvie, 2021, The Journal of Pharmacology and Experimental Therapeutics.

Molecular docking methodologies.

Marco Fanton, Andrea Bortolato, Stefano Moro, 2013, Methods in molecular biology.

Decoding Corticotropin-Releasing Factor Receptor Type 1 Crystal  Structures

R. Read, R. Cheng, A. Bortolato, 2017, Current molecular pharmacology.

Corrigendum: Crystal structure of the GLP-1 receptor bound to a peptide agonist

S. P. Andrews, M. Congreve, J. Mason, 2017, Nature.

Making Structural Sense of Dimerization Interfaces of Delta Opioid Receptor Homodimers

Davide Provasi, Jonathan A. Javitch, Marta Filizola, 2011, Biochemistry.

Exploring molecular mechanisms of ligand recognition by opioid receptors with metadynamics.

Davide Provasi, Marta Filizola, Andrea Bortolato, 2009, Biochemistry.

Total foliar nutrition applied on European hazelnut

A. Bortolato, V. Cristofori, R. Stelliferi, 2018, Acta Horticulturae.

Decoding the Role of Water Dynamics in Ligand-Protein Unbinding: CRF1R as a Test Case

Jonathan S. Mason, Francesca Deflorian, Andrea Bortolato, 2015, J. Chem. Inf. Model..

High end GPCR design: crafted ligand design and druggability analysis using protein structure, lipophilic hotspots and explicit water networks

Dahlia R. Weiss, J. Mason, A. Bortolato, 2013, In Silico Pharmacology.

Altruistic Metadynamics: Multisystem Biased Simulation.

Vojtěch Spiwok, Andrea Bortolato, Petr Hošek, 2016, The journal of physical chemistry. B.

Protein kinase CK2 inhibitors: emerging anticancer therapeutic agents?

S. Moro, A. Bortolato, G. Cozza, 2008, Anti-cancer agents in medicinal chemistry.

In Silico Binding Free Energy Predictability by Using the Linear Interaction Energy (LIE) Method: Bromobenzimidazole CK2 Inhibitors as a Case Study

Stefano Moro, Andrea Bortolato, S. Moro, 2007, J. Chem. Inf. Model..

TEMPORARY REMOVAL: Identification of a novel allosteric GLP-1R antagonist HTL26119 using structure- based drug design.

S. P. Andrews, M. Congreve, J. Mason, 2019, Bioorganic & medicinal chemistry letters.

Novel Macrocyclic Antagonists of the Calcitonin Gene-Related Peptide Receptor: Design, Realization, and Structural Characterization of Protein-Ligand Complexes.

M. Congreve, J. Mason, A. Bortolato, 2022, ACS chemical neuroscience.

How Druggable Is Protein Kinase CK2

S. Moro, A. Bortolato, G. Cozza, 2010 .

Generic GPCR residue numbers - aligning topology maps while minding the gaps.

David E. Gloriam, G. Vriend, R. Stevens, 2015, Trends in pharmacological sciences.

GPCR-Bench: A Benchmarking Set and Practitioners' Guide for G Protein-Coupled Receptor Docking

Jonathan S. Mason, Andrea Bortolato, Dahlia R. Weiss, 2016, J. Chem. Inf. Model..

Designing a ligand for pharmaceutical purposes

S. Moro, A. Bortolato, 2008, Expert opinion on drug discovery.

α‐Naphthylaminopropan‐2‐ol Derivatives as BACE1 Inhibitors

S. Moro, A. Bortolato, S. Rapposelli, 2008, ChemMedChem.