Ó. Delgado

发表

Identification of a novel orally bioavailable phosphodiesterase 10A (PDE10A) inhibitor with efficacy in animal models of schizophrenia.

A. Megens, X. Langlois, J. Bartolomé-Nebreda, 2015, Journal of medicinal chemistry.

Total synthesis of (-)-dictyostatin, a microtubule-stabilising anticancer macrolide of marine sponge origin

Ó. Delgado, I. Paterson, Arndt Meyer, 2010 .

Rational design and synthesis of aminopiperazinones as β-secretase (BACE) inhibitors.

J. Spurlino, F. Delgado, Ó. Delgado, 2011, Bioorganic & medicinal chemistry letters.

A practical entry to β-aryl-β-alkyl amino alcohols: application to the synthesis of a potent BACE1 inhibitor.

Ó. Delgado, Michiel Van Gool, S. Fustero, 2012, Organic & biomolecular chemistry.

Total synthesis of the thiazolyl peptide GE2270 A.

Ó. Delgado, T. Bach, H. Müller, 2007, Angewandte Chemie.

Concise total synthesis of the thiazolyl peptide antibiotic GE2270 A.

Ó. Delgado, T. Bach, H. Müller, 2008, Chemistry.

Fluorinated Pyrazoles and Indazoles

Ó. Delgado, S. Fustero, Raquel Román, 2014 .

Total synthesis of the thiazolyl peptide GE2270 A.

Ó. Delgado, T. Bach, H. Müller, 2007, Angewandte Chemie.

1,4-Oxazine β-Secretase 1 (BACE1) Inhibitors: From Hit Generation to Orally Bioavailable Brain Penetrant Leads.

Ó. Delgado, Michiel Van Gool, J. M. Alonso, 2015, Journal of medicinal chemistry.

Diastereoselective synthesis of 2-phenyl-3-(trifluoromethyl)piperazines as building blocks for drug discovery.

Ó. Delgado, Michiel Van Gool, María Sánchez-Roselló, 2014, The Journal of organic chemistry.

Synthesis and configurational assignment of the amino alcohol in the eastern fragment of the GE2270 antibiotics by regio- and stereoselective addition of 2-metalated 4-bromothiazoles to alpha-chiral electrophiles.

Ó. Delgado, T. Bach, H. Müller, 2006, The Journal of organic chemistry.

Stereochemical determination of dictyostatin, a novel microtubule-stabilising macrolide from the marine sponge Corallistidae sp.

Ó. Delgado, A. Wright, I. Paterson, 2004, Chemical communications.

Synthesis of novel discodermolide analogues with modified hydrogen-bonding donor/acceptor sites

Ó. Delgado, I. Paterson, 2003 .

Total synthesis and configurational assignment of (-)-dictyostatin, a microtubule-stabilizing macrolide of marine sponge origin.

Ó. Delgado, I. Paterson, Arndt Meyer, 2004, Angewandte Chemie.

A second-generation total synthesis of (+)-discodermolide: the development of a practical route using solely substrate-based stereocontrol.

Ian Paterson, Jeremy P. Scott, Ó. Delgado, 2005, The Journal of organic chemistry.

Stereochemical Determination of Dictyostatin, a Novel Microtubule‐Stabilizing Macrolide from the Marine Sponge Corallistidae sp.

Ó. Delgado, A. Wright, I. Paterson, 2004 .

N-Bridged 5,6-bicyclic pyridines: Recent applications in central nervous system disorders.

F. Delgado, Ó. Delgado, J. A. Vega, 2015, European journal of medicinal chemistry.

Design, synthesis, and biological evaluation of novel fluorinated ethanolamines.

Ó. Delgado, G. Tresadern, M. Gütschow, 2011, Chemistry.

A Versatile Approach to CF3 -Containing 2-Pyrrolidones by Tandem Michael Addition-Cyclization: Exemplification in the Synthesis of Amidine Class BACE1 Inhibitors.

Ó. Delgado, Michiel Van Gool, G. Tresadern, 2015, Chemistry.

1,6-asymmetric induction in boron-mediated aldol reactions: application to a practical total synthesis of (+)-discodermolide.

Jeremy P. Scott, Ó. Delgado, I. Paterson, 2003, Organic letters.

A Versatile Approach to CF3 -Containing 2-Pyrrolidones by Tandem Michael Addition-Cyclization: Exemplification in the Synthesis of Amidine Class BACE1 Inhibitors.

Ó. Delgado, Michiel Van Gool, G. Tresadern, 2015, Chemistry.

A Versatile Approach to CF3‐Containing 2‐Pyrrolidones by Tandem Michael Addition—Cyclization: Exemplification in the Synthesis of Amidine Class BACE1 Inhibitors.

Ó. Delgado, G. Tresadern, L. Pérez-Benito, 2016 .

A practical entry to β-aryl-β-alkyl amino alcohols: application to the synthesis of a potent BACE1 inhibitor.

Ó. Delgado, Michiel Van Gool, S. Fustero, 2012, Organic & biomolecular chemistry.