M. Birnbaum
发表
Ming-tao Li,
Xiaomin Wang,
M. K. Meintzer,
2000,
Molecular and Cellular Biology.
David R. Kaplan,
Sandeep Robert Datta,
Rosalind A. Segal,
1997,
Science.
M. Birnbaum,
Zhiyong Zhang,
L. Amorosa,
2016,
Diabetes.
M. Birnbaum,
J. Bruix,
Y. Suárez,
2016,
Hepatology.
M. Birnbaum,
F. Lang,
G. Colussi,
2011,
Molecular endocrinology.
M. Birnbaum,
M. Juntilla,
Vineet Patil,
2010
.
M. Birnbaum,
F. Lang,
J. McCormick,
2009,
FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
M. Birnbaum,
S. Yun,
Eun-Kyoung Kim,
2008,
Biochemical and biophysical research communications.
M. Birnbaum,
D. N. Gross,
A. Heuvel,
2008,
Oncogene.
M. Birnbaum,
David F. Tucker,
S. Bae,
2006,
Journal of Biological Chemistry.
S. J. Kim,
M. Birnbaum,
J. Ha,
2001,
Biochemical and biophysical research communications.
M. Birnbaum,
C. Newgard,
L. Witters,
2007,
Journal of Biological Chemistry.
M. Birnbaum,
J. Brozinick,
1998,
The Journal of Biological Chemistry.
M. Birnbaum,
R. Roth,
A. D. Kohn,
1996,
The Journal of Biological Chemistry.
M. Birnbaum,
B. Neel,
A. Bennett,
1995,
The Journal of Biological Chemistry.
M. Birnbaum,
L. Rameh,
J. Yeh,
1995,
The Journal of Biological Chemistry.
J. Qian,
D. Zack,
A. Gingras,
2013,
Molecular systems biology.
M. Birnbaum,
K. Hoehn,
J. Brozinick,
2007,
Cell metabolism.
M. Birnbaum,
B. Thorens,
F. Beermann,
1997,
Nature Genetics.
M. Birnbaum,
Mingjian Lu,
B. Monks,
2015,
The Journal of Biological Chemistry.
M. Birnbaum,
M. Donowitz,
B. Baibakov,
2004,
Gastroenterology.
M. Birnbaum,
O. Rosen,
Y. Hiraki,
1988,
The Journal of biological chemistry.
M. Birnbaum,
B. Monks,
G. Núñez,
2012,
The Journal of Immunology.
K. Petersen,
G. Shulman,
M. Birnbaum,
2015,
Cell.
M. Birnbaum,
C. Thompson,
K. Hallows,
2010,
Cell.
M. Birnbaum,
1989,
Cell.
B. Viollet,
M. Birnbaum,
J. Wojtaszewski,
2001,
Biochemical Society transactions.
M. Birnbaum,
P. Seale,
B. Monks,
2016,
Molecular metabolism.
M. Keane,
A. Wright,
M. Birnbaum,
2010
.
M. Birnbaum,
G. Sonnenberg,
J. Pfefferkorn,
2021,
Molecular metabolism.
C. Kahn,
M. Birnbaum,
M. White,
1994,
The Journal of biological chemistry.
C. Kahn,
M. Birnbaum,
M. White,
1993,
Molecular and cellular biology.
M. Birnbaum,
O. Rosen,
H. Haspel,
1986,
Proceedings of the National Academy of Sciences of the United States of America.
C. Kahn,
M. Birnbaum,
P. Vollenweider,
2003,
The Journal of clinical investigation.
M. Birnbaum,
N. Hay,
Xiao-Ding Peng,
2016,
Cancer Cell.
M. Birnbaum,
K. Verhey,
Morris J. Birnbaum,
1994,
The Journal of biological chemistry.
J. Weisel,
J. Hartwig,
M. Birnbaum,
2008,
The Journal of clinical investigation.
M. Birnbaum,
G. Kanel,
B. Stiles,
2010,
Gastroenterology.
M. Birnbaum,
V. P. Yin,
S. Summers,
1999,
Annals of the New York Academy of Sciences.
J. Wess,
M. Birnbaum,
H. Kaneto,
2018,
The Journal of clinical investigation.
M. Birnbaum,
B. Thorens,
F. Beermann,
1998,
Nature Genetics.
M. Birnbaum,
1992,
International review of cytology.
M. Birnbaum,
T. Ciaraldi,
W. Garvey,
1991,
The Journal of clinical investigation.
M. Birnbaum,
D. N. Gross,
Min Wan,
2009,
Current diabetes reports.
H. Lodish,
D. James,
M. Birnbaum,
2002,
American journal of physiology. Endocrinology and metabolism.
M. Birnbaum,
J. Diangelo,
2009,
Molecular and Cellular Biology.
M. Birnbaum,
2004,
Developmental cell.
M. Bucan,
M. Birnbaum,
O. Valladares,
2001,
Molecular cell.
M. Birnbaum,
J. Mu,
W. Yin,
2003,
Journal of Biological Chemistry.
M. Birnbaum,
A. Morgans,
L. Brass,
2004,
The Journal of clinical investigation.
M. Birnbaum,
W. Garvey,
T. Huecksteadt,
1989,
Science.
E. Puré,
M. Birnbaum,
H. L. Li,
1999,
Proceedings of the National Academy of Sciences of the United States of America.
G. R. Prescott,
M. Birnbaum,
J. Barclay,
2006,
Journal of Biological Chemistry.
Katherine D Dugan,
L. Chodosh,
M. Birnbaum,
2006,
Cell metabolism.
B. A. Ballif,
M. Birnbaum,
W. Sessa,
2015,
Science Signaling.
G. Shulman,
M. Birnbaum,
S. Previs,
2009,
Cell metabolism.
P. Hammerman,
M. Birnbaum,
C. Thompson,
2005,
Blood.
Joanne I. Yeh,
M. Birnbaum,
K. Verhey,
1995,
The Journal of cell biology.
D. Fingar,
M. Birnbaum,
G. Griffiths,
1993,
The Journal of cell biology.
D. Fingar,
M. Birnbaum,
S. Summers,
1999,
The Journal of Biological Chemistry.
M. Birnbaum,
Y. Hiraki,
I. McMorrow,
1989,
Molecular endocrinology.
M. Birnbaum,
B. Monks,
Q. Ge,
2007,
Nature.
M. Birnbaum,
W. Quinn,
2012,
Proceedings of the National Academy of Sciences.
M. Birnbaum,
Min Wan,
2011,
Cell Metabolism.
M. Birnbaum,
2008,
Science.
M. Birnbaum,
J. T. R. Lawrence,
J. Lawrence,
2003,
Proceedings of the National Academy of Sciences of the United States of America.
M. Birnbaum,
P. Scherer,
J. Brozinick,
2016
.
M. Birnbaum,
K. Bence,
2020,
Molecular metabolism.
M. Birnbaum,
C. Gleason,
D. Gross,
2007,
Proceedings of the National Academy of Sciences of the United States of America.
M. Birnbaum,
2001,
Nature.
Regulation of pancreatic β-cell growth and survival by the serine/threonine protein kinase Akt1/PKBα
E. Furth,
K. Polonsky,
M. Birnbaum,
2001,
Nature Medicine.
M. Birnbaum,
Hui Li,
K. Hallows,
2014,
American journal of physiology. Renal physiology.
M. Birnbaum,
E. Ackah,
W. Sessa,
2005,
The Journal of clinical investigation.
M. Birnbaum,
E. Ackah,
W. Sessa,
2005
.
C. Mahaffey,
S. Danzer,
W. Frankel,
2011,
Human molecular genetics.
M. Birnbaum,
A. Attie,
J. Stoehr,
2001,
American journal of physiology. Endocrinology and metabolism.
C. Kahn,
M. Birnbaum,
K. Ueki,
2011,
Molecular and Cellular Biology.
M. Birnbaum,
R. Cooksey,
Deborah L Jones,
2009,
Circulation Research.
M. Birnbaum,
L. Lipfert,
S. Summers,
1998,
Biochemical and biophysical research communications.
M. Birnbaum,
S. Summers,
L. Lipfert,
1999,
The Journal of Biological Chemistry.
M. Birnbaum,
A. García de Herreros,
1989,
The Journal of biological chemistry.
M. Birnbaum,
S. Izumo,
E. Abel,
2007,
Cell metabolism.
M. Birnbaum,
P. Titchenell,
B. Monks,
2015,
Nature Communications.
K. Kaestner,
D. Guertin,
D. Sabatini,
2011,
Cell metabolism.
M. Birnbaum,
Mingjian Lu,
K. Sakamoto,
2013,
Cell metabolism.
D. Fingar,
M. Birnbaum,
1994,
Endocrinology.
N. Spinner,
M. Birnbaum,
J. Yeh,
1998,
Nature Genetics.
A role for Raf-1 in the divergent signaling pathways mediating insulin-stimulated glucose transport.
D. Fingar,
M. Birnbaum,
1994,
The Journal of biological chemistry.
M. Birnbaum,
Russell A. Miller,
2016,
Diabetologia.
M. Birnbaum,
M. R. Calera,
P. Pilch,
1998,
The Journal of Biological Chemistry.
C. Kahn,
M. Birnbaum,
M. White,
1993,
Proceedings of the National Academy of Sciences of the United States of America.
M. Birnbaum,
G. Dohm,
J. Mu,
2004,
American journal of physiology. Endocrinology and metabolism.
M. Birnbaum,
B. Kemp,
S. Jørgensen,
2009,
Diabetes.
M. Birnbaum,
J. Mu,
E. Barton,
2001,
Biochemical Society transactions.
L. Chodosh,
M. Birnbaum,
James V. Alvarez,
2010,
Breast Cancer Research.
M. Birnbaum,
J. Rathmell,
M. Juntilla,
2007,
Proceedings of the National Academy of Sciences.
K. Kaestner,
G. Shulman,
M. Birnbaum,
2001,
Science.
M. Birnbaum,
J. Rathmell,
B. Krock,
2013,
Nature Immunology.
M. Birnbaum,
J. Rathmell,
B. Krock,
2013,
Nature Immunology.
M. Birnbaum,
J. Rathmell,
M. Juntilla,
2010,
Blood.
M. Birnbaum,
F. Lang,
D. Pearce,
2010,
American journal of physiology. Renal physiology.
M. Birnbaum,
W. El-Deiry,
K. Carroll,
2008
.
M. Birnbaum,
M. Lazar,
C. Steppan,
2005,
Molecular and Cellular Biology.
M. Birnbaum,
E. L. Whiteman,
Janine J Chen,
2003,
Endocrinology.
M. Birnbaum,
O. Rosen,
H. Haspel,
1985,
The Journal of biological chemistry.
M. Birnbaum,
J. Yeh,
K. Verhey,
1995,
Biochemistry.
J. Blenis,
D. Fingar,
M. Birnbaum,
1993,
Journal of Biological Chemistry.
M. Birnbaum,
J. T. R. Lawrence,
J. Lawrence,
2001,
Molecular and Cellular Biology.
M. Birnbaum,
J. Frangioni,
S. Hausdorff,
1994,
The Journal of biological chemistry.
M. Birnbaum,
A. García de Herreros,
1989,
The Journal of biological chemistry.
Honglin Zhou,
M. Birnbaum,
S. Summers,
1998,
The Journal of Biological Chemistry.
M. Birnbaum,
2003,
Journal of Cell Biology.
S. Williams,
M. Birnbaum,
Morris J. Birnbaum,
1988,
The Journal of biological chemistry.
M. Birnbaum,
S. Bae,
J. Mu,
2003,
Journal of Biological Chemistry.
M. Birnbaum,
Sun Young Lee,
S. Yun,
2009,
FEBS letters.
E. Furth,
K. Polonsky,
M. Birnbaum,
2001,
Nature medicine.
D. Rader,
M. Birnbaum,
P. Titchenell,
2017,
The Journal of clinical investigation.
M. Birnbaum,
S. Jørgensen,
G. Steinberg,
2009
.
M. Birnbaum,
W. Garvey,
1993,
Baillière's Clinical Endocrinology and Metabolism.
M. Birnbaum,
D. O’Sullivan,
S. C. Huang,
2018
.
M. Birnbaum,
S. Summers,
1997,
Biochemical Society transactions.
M. Birnbaum,
A. Hudson,
1995,
Proceedings of the National Academy of Sciences of the United States of America.
M. Birnbaum,
J. Rabinowitz,
W. Lu,
2018,
Cell metabolism.
M. Birnbaum,
2002,
Developmental cell.
M. Birnbaum,
J. Rathmell,
M. Juntilla,
2007,
Proceedings of the National Academy of Sciences of the United States of America.
M. Birnbaum,
C. Newgard,
L. Witters,
2007,
The Journal of biological chemistry.
M. Birnbaum,
G. V. D. van der Windt,
D. O’Sullivan,
2018,
Immunity.
M. Birnbaum,
F. Lang,
D. Pearce,
2006,
Cellular Physiology and Biochemistry.
M. Birnbaum,
R. Ballester,
O. Rosen,
1986,
The Journal of biological chemistry.
M. Birnbaum,
F. Pallardó,
S. Vannucci,
1993,
The Journal of biological chemistry.
M. Birnbaum,
2005,
Cell Metabolism.
B. Viollet,
M. Birnbaum,
D. Carling,
2003,
The Journal of clinical investigation.
David N. Groff,
M. Birnbaum,
R. Kulkarni,
2014,
Molecular metabolism.
M. Birnbaum,
J. Rathmell,
B. Krock,
2014,
Nature Immunology.
M. Birnbaum,
J. Baxter,
1986,
Journal of Biological Chemistry.
Russell G. Jones,
M. Birnbaum,
C. Thompson,
2005,
Molecular cell.
G. Shulman,
M. Birnbaum,
L. Young,
2002,
Proceedings of the National Academy of Sciences of the United States of America.
M. Birnbaum,
A. Barthel,
R. Roth,
1998,
The Journal of Biological Chemistry.
E. Wilder,
M. Birnbaum,
M. Buratovich,
1999,
Nature Cell Biology.
M. Birnbaum,
M. Madesh,
J. Foskett,
2012,
Cell.
M. Birnbaum,
E. L. Whiteman,
2003,
Methods in molecular medicine.
T. Ludwig,
M. Birnbaum,
M. Forman,
2005,
Molecular and cellular biology.
H. Lodish,
D. James,
M. Birnbaum,
2011
.
R A Roth,
M. Birnbaum,
R. Roth,
1999,
The Journal of Biological Chemistry.
K. Kaestner,
G. Shulman,
M. Birnbaum,
2001
.
B. Viollet,
M. Birnbaum,
M. Foretz,
2016
.
M. Birnbaum,
S. Cherry,
Shelly A Bambina,
2009,
Proceedings of the National Academy of Sciences.
M. Birnbaum,
O. Rosen,
H. Haspel,
1987,
Science.
M. Birnbaum,
S. Bae,
E. Schaefer,
2003,
The Journal of Biological Chemistry.
Hua Tang,
M. Birnbaum,
S. Bae,
2002,
Molecular and Cellular Biology.
M. Birnbaum,
B. Xue,
Y. Minokoshi,
2004,
Nature.
S. Germain,
M. Birnbaum,
M. Pende,
2008,
The Journal of clinical investigation.
C. Kahn,
M. Birnbaum,
R. Ahima,
2012,
Nature Medicine.
M. Birnbaum,
G. V. D. van der Windt,
S. C. Huang,
2014,
Immunity.
M. Birnbaum,
A. García de Herreros,
Y. Hiraki,
1989,
Proceedings of the National Academy of Sciences of the United States of America.
M. Birnbaum,
2012
.
M. Birnbaum,
2001,
The Journal of clinical investigation.
M. Birnbaum,
J. Rutkowski,
G. Tennekoon,
2001,
Molecular and Cellular Neuroscience.
Honglin Zhou,
M. Birnbaum,
S. Summers,
1998,
Molecular and Cellular Biology.
M. Birnbaum,
W. Garvey,
1993
.
M. Birnbaum,
J. Thorvaldsen,
Q. Chu,
2001,
The Journal of Biological Chemistry.
M. Birnbaum,
J. Backer,
G. V. Prendergast,
1999,
Molecular and Cellular Biology.
M. Birnbaum,
2005,
Anthropology & medicine.
D. James,
M. Birnbaum,
J. Stöckli,
2021,
Nature Reviews Molecular Cell Biology.
M. Birnbaum,
B. Margolis,
D. Meyer,
2002,
Neuron.
M. Birnbaum,
M. Ruiz,
A. Hudson,
1992,
The Journal of cell biology.
M. Febbraio,
M. Birnbaum,
R. Southgate,
2005,
The FASEB Journal.
M. Birnbaum,
E. L. Whiteman,
Han Cho,
2002,
Trends in Endocrinology & Metabolism.
M. Birnbaum,
Zhidan Wu,
A. Joyce,
2020,
Cell metabolism.
M. Birnbaum,
P. Seale,
Lisa M. DiPilato,
2015,
Molecular and Cellular Biology.
M. Birnbaum,
Lisa M. DiPilato,
B. Monks,
2010,
Molecular and Cellular Biology.
T. Ludwig,
M. Birnbaum,
M. Forman,
2005,
Molecular and Cellular Biology.
M. Keane,
A. Wright,
M. Birnbaum,
2010,
American journal of physiology. Heart and circulatory physiology.
M. Birnbaum,
J. Keaney,
K. Walsh,
2002,
The Journal of Biological Chemistry.
M. Birnbaum,
C. Treins,
M. Pende,
2012,
Molecular and Cellular Biology.
M. Birnbaum,
M. Juntilla,
Vineet Patil,
2010,
Blood.
M. Birnbaum,
M. Guha,
N. Avadhani,
2010,
Molecular biology of the cell.
M. Birnbaum,
R. Muschel,
E. Bernhard,
2005,
Cancer research.
M. Birnbaum,
J. H. Kim,
S. Yun,
2008,
Experimental and Molecular Medicine.
M. Birnbaum,
M. Lazar,
P. Titchenell,
2017,
Trends in Endocrinology & Metabolism.
K. Kaestner,
B. Viollet,
N. Gray,
2014,
Nature Communications.
K. Kaestner,
B. Viollet,
N. Gray,
2014
.
M. Birnbaum,
Karla F. Leavens,
2011,
Critical reviews in biochemistry and molecular biology.
Wesley T. Kerr,
M. Birnbaum,
G. Koretzky,
2005,
Blood.
M. Birnbaum,
A. Keene,
J. Diangelo,
2012,
Biochemical and biophysical research communications.
Hong Wang,
G. Shulman,
M. Birnbaum,
2012,
Nature Medicine.
Laura A. Solt,
Craig B. Thompson,
M. Birnbaum,
2004,
Science.
M. Birnbaum,
C. Thompson,
Ryan M. Cinalli,
2004,
Science.
M. Birnbaum,
A. Sancar,
P. Titchenell,
2016,
Nature Communications.
M. Karayiorgou,
E. Emamian,
M. Birnbaum,
2004,
Nature Genetics.
D. James,
M. Birnbaum,
David F. Tucker,
1999,
Molecular and Cellular Biology.
M. Birnbaum,
Fajun Yang,
J. Pessin,
2015,
PloS one.
J. Cheng,
M. Birnbaum,
D. Chappell,
2005,
Journal of Biological Chemistry.
M. Birnbaum,
C. Zechner,
R. Russell,
2004,
The Journal of clinical investigation.
M. Birnbaum,
R. Shaw,
2011,
Nature.
M. Birnbaum,
O. Rosen,
R. Herrera,
1986,
Proceedings of the National Academy of Sciences of the United States of America.
Receptor-mediated activation of ceramidase activity initiates the pleiotropic actions of adiponectin
M. Birnbaum,
P. Scherer,
J. Brozinick,
2011,
Nature Medicine.
M. Birnbaum,
W. Garvey,
T. Huecksteadt,
1989,
Molecular endocrinology.
M. Birnbaum,
M. Bland,
Stephen W. Roth,
2018,
Cell reports.
M. Birnbaum,
A. Fisher,
Nankang Hong,
2012,
American journal of physiology. Heart and circulatory physiology.
M. Birnbaum,
J. Rabinowitz,
W. Lu,
2016,
Cell metabolism.
I. Lucki,
M. Birnbaum,
K. Talbot,
2012,
Hippocampus.
M. Birnbaum,
Lisa M. DiPilato,
B. Monks,
2015,
Diabetologia.
N. Sonenberg,
M. Birnbaum,
P. Lasko,
2001,
Nature Cell Biology.
M. Birnbaum,
S. Hausdorff,
K. Verhey,
1993,
The Journal of cell biology.
K. Kaestner,
B. Viollet,
M. Birnbaum,
2011,
The Journal of clinical investigation.
M. Birnbaum,
2005,
Molecular cell.
O. Ljungqvist,
M. Birnbaum,
N. Fujii,
2000,
Biochemical and biophysical research communications.
M. Birnbaum,
Laurent Beuret,
J. Charron,
2013,
The Journal of Biological Chemistry.
M. Birnbaum,
B. Thorens,
F. Beermann,
1998,
Nature Genetics.
Jeffrey L Carson,
M. Birnbaum,
Zhiyong Zhang,
2015,
The Journal of Immunology.
M. Birnbaum,
Russell A. Miller,
2010,
The Journal of clinical investigation.
M. Birnbaum,
M. Herman,
2021,
Cell metabolism.
M. Birnbaum,
A. Rustgi,
H. Nakagawa,
2000,
The Journal of Biological Chemistry.
M. Birnbaum,
E. Ackah,
Y. Suárez,
2007,
Cell metabolism.
L. Petrucelli,
J. Cheng,
M. Birnbaum,
2008,
Proceedings of the National Academy of Sciences.
Marcus D. Goncalves,
M. Birnbaum,
R. Ahima,
2010,
PloS one.
M. Birnbaum,
B. Monks,
J. Welti,
2007,
Journal of Biological Chemistry.
M. Birnbaum,
N. Doliba,
D. Stoffers,
2019,
Molecular metabolism.
M. Birnbaum,
G. Ronnett,
Wendy Keung,
2007,
Proceedings of the National Academy of Sciences.
M. Birnbaum,
D. Littman,
Jiong Wu,
2004,
Journal of Biological Chemistry.
M. Birnbaum,
D. Littman,
Jiong Wu,
2004,
The Journal of biological chemistry.
M. Birnbaum,
Jake E. Delmore,
A. Kalgutkar,
2018,
EBioMedicine.
R. Kurumbail,
M. Birnbaum,
A. Kalgutkar,
2017,
The Journal of Pharmacology and Experimental Therapeutics.
M. Birnbaum,
J. Baur,
2014,
Cell Metabolism.
K. Kaestner,
M. Birnbaum,
J. Pintar,
2009,
Endocrine reviews.
K. Kaestner,
M. Birnbaum,
J. Pintar,
2009,
Endocrine reviews.
A. T. Young,
P. Bauer,
M. Birnbaum,
1995,
Proceedings of the National Academy of Sciences of the United States of America.
T. Abel,
A. Sehgal,
D. Dinges,
2015,
Proceedings of the National Academy of Sciences.
M. Birnbaum,
You Wang,
D. Stoffers,
2010,
Proceedings of the National Academy of Sciences of the United States of America.
M. Birnbaum,
D. Kazierad,
A. Bergman,
2021,
Med.
M. Birnbaum,
M. Pontoglio,
J. Scoazec,
2012,
Nature Communications.
M. Birnbaum,
J. Rabinowitz,
W. Lu,
2018,
Nature Medicine.
M. Birnbaum,
R. Lee,
J. Foskett,
2010,
Developmental biology.
M. Birnbaum,
O. Rosen,
S. Cushman,
1986,
The Journal of biological chemistry.
M. Birnbaum,
LUIS A. Garza,
2000,
The Journal of Biological Chemistry.
M. Birnbaum,
J. H. Kim,
S. Yun,
2008,
Cellular signalling.
Donal N. Gorman,
M. Birnbaum,
J. Frias,
2023,
JAMA network open.
M. Birnbaum,
X. Liu,
V. Giranda,
2006,
Journal of Biological Chemistry.
Jeonifer M. Garren,
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bioRxiv.
M. Birnbaum,
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Science.
E. Chen,
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DNA.
J. Weisel,
J. Hartwig,
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The Journal of clinical investigation.
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Cell metabolism.
J. Qian,
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Molecular systems biology.
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D. Fingar,
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The American journal of pathology.
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Nature Medicine.
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Hepatology.
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The Journal of clinical investigation.
Donal N. Gorman,
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Diabetes, obesity and metabolism.
M. Birnbaum,
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Molecular and Cellular Biology.
O. Bezy,
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Nature communications.
M. Birnbaum,
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Nature Medicine.
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Molecular and Cellular Biology.
K. Kaestner,
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Molecular and Cellular Biology.
M. Birnbaum,
F. Lang,
G. Colussi,
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Molecular endocrinology.
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J. Weisel,
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Cell metabolism.