D. Banner

发表

A Real-World Perspective on Molecular Design.

W. Guba, J. Hert, B. Kuhn, 2016, Journal of medicinal chemistry.

Crystallographic analysis at 3.0-A resolution of the binding to human thrombin of four active site-directed inhibitors.

D. Banner, P. Hadváry, 1994, The Journal of biological chemistry.

Crystal structure of the soluble human 55 kd TNF receptor-human TNFβ complex: Implications for TNF receptor activation

D. Banner, R. Gentz, A. D'arcy, 1993, Cell.

The crystal structure of the complex of blood coagulation factor VIIa with soluble tissue factor

David W. Banner, Arabinda Guha, Yale Nemerson, 1996, Nature.

Structure of the ColE1 rop protein at 1.7 A resolution.

M Kokkinidis, D W Banner, D Tsernoglou, 1987, Journal of molecular biology.

Structure of chicken muscle triose phosphate isomerase determined crystallographically at 2.5Å resolution: using amino acid sequence data

G. Petsko, D. Phillips, I. Wilson, 1975, Nature.

Structure of the protein and DNA in fd filamentous bacterial virus

D. Banner, D. Marvin, C. Nave, 1981, Nature.

Inherited Factor X Deficiency: Molecular Genetics and Pathophysiology

D. Cooper, D. Banner, A. Wacey, 1997, Thrombosis and Haemostasis.

Mapping the conformational space accessible to BACE2 using surface mutants and cocrystals with Fab fragments, Fynomers and Xaperones.

D. Banner, A. Kuglstatter, J. Steyaert, 2013, Acta crystallographica. Section D, Biological crystallography.

Cation-pi interactions at the active site of factor Xa: dramatic enhancement upon stepwise N-alkylation of ammonium ions.

F. Diederich, D. Banner, W. Haap, 2009, Angewandte Chemie.

Molecular recognition at the active site of factor Xa: cation-π interactions, stacking on planar peptide surfaces, and replacement of structural water.

F. Diederich, D. Banner, W. Haap, 2012, Chemistry.

Human tumor necrosis factor alpha (TNF alpha) mutants with exclusive specificity for the 55-kDa or 75-kDa TNF receptors.

D. Banner, H. Loetscher, W. Lesslauer, 1993, The Journal of biological chemistry.

Fluorine in Medicinal Chemistry

Martin Stahl, Manfred Kansy, Hans-Joachim Böhm, 2004, Chembiochem : a European journal of chemical biology.

Halogen Bonding at the Active Sites of Human Cathepsin L and MEK1 Kinase: Efficient Interactions in Different Environments

Nobuo Shimma, François Diederich, Jörg Benz, 2011, ChemMedChem.

Systematic investigation of halogen bonding in protein-ligand interactions.

François Diederich, Jörg Benz, Bernd Kuhn, 2011, Angewandte Chemie.

β-Secretase (BACE1) inhibitors with high in vivo efficacy suitable for clinical evaluation in Alzheimer's disease.

Wolfgang Guba, Harald Mauser, Mark Rogers-Evans, 2013, Journal of medicinal chemistry.

Fragment-Based Screening Using Surface Plasmon Resonance Technology

Walter Huber, Francis Müller, Samantha Perspicace, 2009, Journal of biomolecular screening.

The crystal structure of EcoRV endonuclease and of its complexes with cognate and non‐cognate DNA fragments.

K S Wilson, D W Banner, D Tsernoglou, 1993, The EMBO journal.

Mapping the Fluorophilicity of a Hydrophobic Pocket: Synthesis and Biological Evaluation of Tricyclic Thrombin Inhibitors Directing Fluorinated Alkyl Groups into the P Pocket

F. Diederich, D. Banner, M. Kansy, 2006, ChemMedChem.

A fluorine scan of the phenylamidinium needle of tricyclic thrombin inhibitors: effects of fluorine substitution on pKa and binding affinity and evidence for intermolecular C-F...CN interactions.

F. Diederich, D. Banner, M. Kansy, 2004, Organic & biomolecular chemistry.

The Factor Vlla / Tissue Factor Complex

D. Banner, 1997, Thrombosis and Haemostasis.

CXCL14 deficiency does not impact the outcome of influenza or Escherichia coli infections in mice.

D. Banner, D. Kelvin, T. Rowe, 2014, Journal of infection in developing countries.

CXCL10 contributes to p38-mediated apoptosis in primary T lymphocytes in vitro

D. Banner, M. Cameron, D. Kelvin, 2012, Cytokine.

Synthesis of Novel Nonpeptidic Thrombin Inhibitors

F. Diederich, L. Weber, D. Banner, 2000 .

Inflammatory Cytokine Expression Is Associated with Chikungunya Virus Resolution and Symptom Severity

S. Rubino, D. Banner, M. Cameron, 2011, PLoS neglected tropical diseases.

Seasonal H1N1 Influenza Virus Infection Induces Cross-Protective Pandemic H1N1 Virus Immunity through a CD8-Independent, B Cell-Dependent Mechanism

Stephen S. H. Huang, D. Banner, D. Kelvin, 2011, Journal of Virology.

Cortical spreading depression transiently activates MAP kinases.

D. Banner, C. Thompson, A. Hakim, 2002, Brain research. Molecular brain research.

Direct association between pharyngeal viral secretion and host cytokine response in severe pandemic influenza

J. Rello, D. Banner, T. Pumarola, 2011, BMC infectious diseases.

Impaired heterologous immunity in aged ferrets during sequential influenza A H1N1 infection.

Stephen S. H. Huang, D. Banner, D. Kelvin, 2014, Virology.

In vivo ribavirin activity against severe pandemic H1N1 Influenza A/Mexico/4108/2009.

Stephen S. H. Huang, S. Rubino, D. Banner, 2010, The Journal of general virology.

The Diaphanous Inhibitory Domain/Diaphanous Autoregulatory Domain Interaction Is Able to Mediate Heterodimerization between mDia1 and mDia2*

D. Banner, J. Copeland, Giuseppe A. Papalia, 2007, Journal of Biological Chemistry.

The current state of H5N1 vaccines and the use of the ferret model for influenza therapeutic and prophylactic development.

D. Banner, A. Kelvin, 2012, Journal of infection in developing countries.

Crystallographic studies of chicken triose phosphate isomerase.

G. Petsko, D. Phillips, D. Banner, 1972, Cold Spring Harbor symposia on quantitative biology.

Influenza-Associated Encephalopathy With Elevated Antibody Titers to Pandemic (H1N1) 2009 Influenza

D. Banner, D. Kelvin, T. Rowe, 2011, Journal of child neurology.

Influenza monitoring in Sardinia, Italy identifies H3 subtype in Mediterranean wild migratory birds.

S. Rubino, D. Banner, G. Fadda, 2012, Journal of infection in developing countries.

Infectivity, Transmission, and Pathology of Human-Isolated H7N9 Influenza Virus in Ferrets and Pigs

Y. Guan, R. Webster, R. Webby, 2013, Science.

Cloning, expression and immunoassay detection of ferret IFN-γ

D. Banner, M. Cameron, D. Kelvin, 2008, Developmental & Comparative Immunology.

Mesenchymal Stromal (Stem) Cell Therapy Fails to Improve Outcomes in Experimental Severe Influenza

D. Banner, K. Kain, W. Liles, 2013, PloS one.

Molecular Characterization of In Vivo Adjuvant Activity in Ferrets Vaccinated against Inﬂuenza Virus (cid:1)

Y. Guan, Honglin Chen, D. Banner, 2010 .

Selective and orally bioavailable phenylglycine tissue factor/factor VIIa inhibitors.

L. Weber, D. Banner, M. Stahl, 2005, Bioorganic & medicinal chemistry letters.

Enantiomerically Pure Thrombin Inhibitors for Exploring the Molecular-Recognition Features of the Oxyanion Hole

F. Diederich, D. Banner, M. Morgenthaler, 2004 .

Lack of group X secreted phospholipase A2 increases survival following pandemic H1N1 influenza infection

Stephen S. H. Huang, M. Gelb, D. Banner, 2014, Virology.

Activation of blood coagulation factor VIIa with cleaved tissue factor extracellular domain and crystallization of the active complex

D. Banner, A. D'arcy, C. Chene, 1995, Proteins.

Identification of potent and selective cathepsin S inhibitors containing different central cyclic scaffolds.

D. Banner, W. Haap, A. Kuglstatter, 2013, Journal of medicinal chemistry.

Design of Novel, Nonpeptidic Thrombin Inhibitors and Structure of a Thrombin–Inhibitor Complex

F. Diederich, L. Weber, D. Banner, 1995 .

Human Tumor Necrosis Factor a (TNF'a) Mutants with Exclusive Specificity for the 55-kDa or 75-kDa TNF' Receptors*

D. Banner, H. Loetscher, D. Stueber, 2001 .

The crystal structure of EcoRV endonuclease and of its complexes with cognate and non-cognate DNA fragments.

R. Bryan, F. Winkler, D. Banner, 1993 .

Generation, characterization and structural data of chymase binding proteins based on the human Fyn kinase SH3 domain

D. Banner, A. Rufer, M. Hennig, 2012, mAbs.

Guinea Pig Chymase Is Leucine-specific

D. Banner, H. Mauser, D. Schlatter, 2008, Journal of Biological Chemistry.

Synthesis of Novel Nonpeptidic Thrombin Inhibitors.

F. Diederich, L. Weber, D. Banner, 2000 .

Crystallization of the ColE1 Rop protein.

G. Cesareni, D. Banner, D. Tsernoglou, 1983, Journal of molecular biology.

Control of ColE1 replication: low affinity specific binding of Rop (Rom) to RNAI and RNAII.

M. Helmer-Citterich, G. Cesareni, D. Banner, 1988, The EMBO journal.

A Selective, Slow Binding Inhibitor of Factor VIIa Binds to a Nonstandard Active Site Conformation and Attenuates Thrombus Formation in Vivo*

D. Banner, M. Ultsch, D. Sutherlin, 2005, Journal of Biological Chemistry.

Design of selective phenylglycine amide tissue factor/factor VIIa inhibitors.

L. Weber, D. Banner, A. D'arcy, 2005, Bioorganic & medicinal chemistry letters.

Selective and orally bioavailable phenylglycine tissue factor/factor VIIa inhibitors.

L. Weber, D. Banner, M. Stahl, 2005, Bioorganic & medicinal chemistry letters.

Dose-dependent antithrombotic activity of an orally active tissue factor/factor VIIa inhibitor without concomitant enhancement of bleeding propensity.

D. Banner, M. Stahl, T. Lavé, 2006, Bioorganic & medicinal chemistry.

Combinatorial docking and combinatorial chemistry: Design of potent non-peptide thrombin inhibitors

Hans-Joachim Böhm, Lutz Weber, David W. Banner, 1999, J. Comput. Aided Mol. Des..

Enzyme Inhibitor Design

D. Banner, 2008 .

Safety of Perioperative Aprotinin Administration During Isolated Coronary Artery Bypass Graft Surgery: Insights From the ART (Arterial Revascularization Trial)

M. Barman, B. Prendergast, G. Angelini, 2018, Journal of the American Heart Association.

Molecular and structural advances in tissue factor-dependent coagulation.

D. Banner, D. Kirchhofer, 1997, Trends in cardiovascular medicine.

Molecular and Structural Tissue Factor-Dependent

D. Banner, D. Kirchhofer, 1997 .

Discovery of a factor Xa inhibitor (3R,4R)-1-(2,2-difluoro-ethyl)-pyrrolidine-3,4-dicarboxylic acid 3-[(5-chloro-pyridin-2-yl)-amide] 4-[[2-fluoro-4-(2-oxo-2H-pyridin-1-yl)-phenyl]-amide] as a clinical candidate.

Martin Stahl, Walter Huber, Jörg Benz, 2010, Bioorganic & medicinal chemistry letters.

Design and synthesis of potent and highly selective thrombin inhibitors.

K Gubernator, D W Banner, D. Banner, 1994, Journal of medicinal chemistry.

2-(2-Oxo-1,4-dihydro-2H-quinazolin-3-yl)- and 2-(2,2-dioxo-1,4-dihydro-2H-2lambda6-benzo[1,2,6]thiadiazin-3-yl)-N-hydroxy-acetamides as potent and selective peptide deformylase inhibitors.

D. Banner, H. Locher, F. Marlin, 2001, Journal of medicinal chemistry.

A 2.0-A structure of the blue copper protein (cupredoxin) from Alcaligenes faecalis S-6.

D. Banner, D. Tsernoglou, S. Turley, 1989, The Journal of biological chemistry.

Hydroxamic acid derivatives as potent peptide deformylase inhibitors and antibacterial agents.

M. Page, D. Banner, G. Rosse, 2000, Journal of medicinal chemistry.

The crystal structure of pseudoazurin from Alcaligenes faecalis S‐6 determined at 2.9 Å resolution

D. Banner, D. Tsernoglou, K. Wilson, 1987, FEBS letters.

A fluorine scan of thrombin inhibitors to map the fluorophilicity/fluorophobicity of an enzyme active site: evidence for C-F...C=O interactions.

Paul Seiler, François Diederich, F. Diederich, 2003, Angewandte Chemie.

9 Ferret TNF-α and IFN-γ Immunoassays Alyson

D. Banner, D. Kelvin, A. Danesh, 2018 .

Ferret TNF-α and IFN-γ Immunoassays

D. Banner, D. Kelvin, A. Danesh, 2012 .

COMPARISON BETWEEN STEEN AND SOMAH SOLUTIONS AS PRIMARY PERFUSATE COMPONENTS FOR EX VIVO HEART PERFUSION

D. Banner, V. Rao, M. Meineri, 2017 .

Regulation of plasmid copy number by complementary RNAs

G. Cesareni, D. Banner, 1985 .

Crystal structures of uninhibited factor VIIa link its cofactor and substrate-assisted activation to specific interactions.

R. Huber, D. Banner, A. D'arcy, 2002, Journal of molecular biology.

Fluorine Interactions at the Thrombin Active Site: Protein Backbone Fragments HCαCO Comprise a Favorable CF Environment and Interactions of CF with Electrophiles

Manfred Kansy, Björn Wagner, Paul Seiler, 2004, Chembiochem : a European journal of chemical biology.

Influenza Transmission in the Mother-Infant Dyad Leads to Severe Disease, Mammary Gland Infection, and Pathogenesis by Regulating Host Responses

Stephen S. H. Huang, D. Banner, D. Kelvin, 2015, PLoS pathogens.

Host adaptive immunity deficiency in severe pandemic influenza

J. Rello, D. Banner, T. Pumarola, 2010, Critical care.

2‐Diethylamino‐2',6'‐acetoxylidide (lidocaine)

A. W. Hanson, D. Banner, 1974 .

Pathogenic influenza B virus in the ferret model establishes lower respiratory tract infection

Stephen S. H. Huang, D. Banner, D. Kelvin, 2014, The Journal of general virology.

Comparative Analyses of Pandemic H1N1 and Seasonal H1N1, H3N2, and Influenza B Infections Depict Distinct Clinical Pictures in Ferrets

Stephen S. H. Huang, D. Banner, D. Kelvin, 2011, PloS one.

Cloning, expression and characterization of ferret CXCL10

D. Banner, M. Cameron, D. Kelvin, 2007, Molecular Immunology.

Modeling host responses in ferrets during A/California/07/2009 influenza infection.

D. Banner, C. Wiley, M. Cameron, 2010, Virology.

Guinea Pig Chymase Is Leucine-specific

D. Banner, H. Mauser, D. Schlatter, 2008, Journal of Biological Chemistry.

Sequencing, Annotation, and Characterization of the Influenza Ferret Infectome

Stephen S. H. Huang, Zhiyu Peng, D. Banner, 2012, Journal of Virology.

The crystal structure of carnitine palmitoyltransferase 2 and implications for diabetes treatment.

Jörg Benz, D. Banner, A. Rufer, 2006, Structure.

Atomic coordinates for triose phosphate isomerase from chicken muscle.

D W Banner, G A Petsko, G. Petsko, 1976, Biochemical and biophysical research communications.

A New Multi-Mode Perfusion System for Ex Vivo Heart Perfusion Study

Liming Xin, Jean Zu, Massimiliano Meineri, 2018, Journal of Medical Systems.

Coagulation Factor VII Gln100 → Arg

D. Banner, E. Tuddenham, J. McVey, 1998, The Journal of Biological Chemistry.

Inherited Factor VII Deficiency: Molecular Genetics and Pathophysiology

D. Cooper, D. Banner, A. Wacey, 1997, Thrombosis and Haemostasis.

Repurposing a Library of Human Cathepsin L Ligands: Identification of Macrocyclic Lactams as Potent Rhodesain and Trypanosoma brucei Inhibitors.

F. Diederich, B. Kuhn, D. Banner, 2018, Journal of medicinal chemistry.

Optimization of Triazine Nitriles as Rhodesain Inhibitors: Structure–Activity Relationships, Bioisosteric Imidazopyridine Nitriles, and X‐ray Crystal Structure Analysis with Human Cathepsin L

F. Diederich, D. Banner, W. Haap, 2013, ChemMedChem.

Th1 and Th17 hypercytokinemia as early host response signature in severe pandemic influenza

J. Rello, D. Banner, T. Pumarola, 2009, Critical care.

Two Distinct Tumor Necrosis Factor Receptors in Health and Disease

D. Banner, R. Gentz, H. Schoenfeld, 1993 .

Quantification of cation-pi interactions in protein-ligand complexes: crystal-structure analysis of Factor Xa bound to a quaternary ammonium ion ligand.

François Diederich, Jörg Benz, Daniel Schlatter, 2005, Angewandte Chemie.

Multipolar interactions in the D pocket of thrombin: large differences between tricyclic imide and lactam inhibitors.

Manfred Kansy, Björn Wagner, Paul Seiler, 2006, Organic & biomolecular chemistry.

Structure-based design of peptidomimetic antagonists of p56lck SH2 domain

I. E. Smith, N. Borkakoti, D. Banner, 2002 .

Molecular Characterization of In Vivo Adjuvant Activity in Ferrets Vaccinated against Influenza Virus

Y. Guan, Honglin Chen, D. Banner, 2010, Journal of Virology.

Structure-based approaches in modern drug discovery research.

F K Winkler, D W Banner, H J Böhm, 2001, Ernst Schering Research Foundation workshop.

Interleukin-6 Is a Potential Biomarker for Severe Pandemic H1N1 Influenza A Infection

Stephen S. H. Huang, S. Rubino, J. Rello, 2012, PloS one.

Preliminary characterization of crystals of nitrite reductase isolated from Alcaligenes faecalis strain S-6.

D. Banner, D. Tsernoglou, T. Beppu, 1986, Journal of molecular biology.

Crystal structures of Candida albicans N-myristoyltransferase with two distinct inhibitors.

F. Winkler, D. Banner, A. D'arcy, 2002, Chemistry & biology.

Immunity toward H1N1 influenza hemagglutinin of historical and contemporary strains suggests protection and vaccine failure

Stephen S. H. Huang, S. Rubino, Y. Guan, 2013, Scientific Reports.

Title Immunity toward H 1 N 1 influenza hemagglutinin of historical andcontemporary strains suggests protection and vaccine failure

Stephen S. H. Huang, S. Rubino, Y. Guan, 2013 .

On the three-dimensional structure and catalytic mechanism of triose phosphate isomerase.

D W Banner, G A Petsko, G. Petsko, 1981, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.

Crystal structure of L-Pro-L-Leu-Aib-Aib-L-Glu-L-Valol, the C-terminal hexapeptide fragment of trichotoxin.

D. Banner, D. Tsernoglou, H. Brückner, 1986, Biochemical and biophysical research communications.

Enzymology: Not just an active site

D. Banner, 2000, Nature.

Maximum entropy calculation of electron density with native and single isomorphous replacement data

R. Bryan, D. Banner, 1987 .

Pandemic H1N1 influenza A directly induces a robust and acute inflammatory gene signature in primary human bronchial epithelial cells downstream of membrane fusion.

Stephen S. H. Huang, D. Banner, D. Kelvin, 2014, Virology.

Inhibitor binding to thrombin: x-ray crystallographic studies.

D. Banner, P. Hadváry, 1993, Advances in experimental medicine and biology.

Next-generation sequencing and bioinformatic approaches to detect and analyze influenza virus in ferrets.

G. Wong, D. Banner, D. Kelvin, 2014, Journal of infection in developing countries.

Design of novel aminopyrrolidine factor Xa inhibitors from a screening hit.

Martin Stahl, Jörg Benz, Daniel Schlatter, 2009, European journal of medicinal chemistry.

BACE1 inhibitors: a head group scan on a series of amides.

W. Guba, D. Banner, E. Pinard, 2013, Bioorganic & medicinal chemistry letters.

GALA-based SOM (Somah) Protects Coronary Endothelial and Vasomotor Function Following Ex Vivo Heart Perfusion

D. Banner, V. Rao, M. Meineri, 2018 .

EFFECT OF SOMAH SOLUTION ON HYPOXIA/REOXYGENATION INDUCED CORONARY ARTERY ENDOTHELIAL INJURY: A COMPARISON TO CURRENT EX-VIVO HEART PERFUSATES

D. Banner, V. Rao, M. Badiwala, 2016 .

Control of initiation of pMB1 replication: Purified rop protein and RNA I affect primer formation in vitro

L. Castagnoli, G. Cesareni, D. Banner, 1984, Cell.

How does Rop work?

L. Castagnoli, G. Cesareni, D. Banner, 1984, Advances in Experimental Medicine and Biology.

A multiple-counter X-ray diffractometer with equatorial geometry

D. Banner, D. J. Marsh, P. R. Evans, 1977 .

Molecular recognition at the thrombin active site: structure-based design and synthesis of potent and selective thrombin inhibitors and the X-ray crystal structures of two thrombin-inhibitor complexes.

D W Banner, F. Diederich, L. Weber, 1997, Chemistry & biology.

Sequencing, Annotation, and Characterization of the Influenza Ferret Infectome

Stephen S. H. Huang, Zhiyu Peng, D. Banner, 2012, Journal of Virology.

Crystallization and preliminary crystallographic analysis of a TNF-beta-55 kDa TNF receptor complex.

F. Winkler, D. Banner, R. Gentz, 1993, Journal of molecular biology.