J. Toulmé

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Is a Closing “GA Pair” a Rule for Stable Loop-Loop RNA Complexes?*

F. Ducongé, C. Di Primo, J. Toulmé, 2000, The Journal of Biological Chemistry.

Ex Vivo and In Vivo Imaging and Biodistribution of Aptamers Targeting the Human Matrix MetalloProtease-9 in Melanomas

J. Toulmé, David Kryza, F. Debordeaux, 2016, PloS one.

DNA Aptamers Selected Against the HIV-1trans-Activation-responsive RNA Element Form RNA-DNA Kissing Complexes*

J. Toulmé, C. Boiziau, É. Dausse, 1999, The Journal of Biological Chemistry.

NMR structure of a kissing complex formed between the TAR RNA element of HIV-1 and a LNA-modified aptamer

C. Di Primo, J. Toulmé, I. Lebars, 2007, Nucleic acids research.

A Boost for the Emerging Field of RNA Nanotechnology

J. Toulmé, S. Tenenbaum, J. Rossi, 2011, ACS nano.

Use of dynamic combinatorial chemistry for the identification of covalently appended residues that stabilize oligonucleotide complexes.

J. Toulmé, B. Rayner, A. Bugaut, 2004, Angewandte Chemie.

Electrostatics Explains the Position-Dependent Effect of G⋅U Wobble Base Pairs on the Affinity of RNA Kissing Complexes.

J. Toulmé, M. Porrini, É. Dausse, 2017, Chemphyschem : a European journal of chemical physics and physical chemistry.

LNA/DNA chimeric oligomers mimic RNA aptamers targeted to the TAR RNA element of HIV-1.

C. Di Primo, J. Toulmé, F. Darfeuille, 2004, Nucleic Acids Research.

Phosphorothioate oligonucleotides derived from human immunodeficiency virus type 1 (HIV-1) primer tRNALys3 are strong inhibitors of HIV-1 reverse transcriptase and arrest viral replication in infected cells

J. Toulmé, H. Fleury, S. Litvak, 1997, Antimicrobial agents and chemotherapy.

Double Hairpin Complexes Allow Accommodation of All Four Base Pairs in Triple Helices Containing Both DNA and RNA Strands*

J. Toulmé, E. Pascolo, 1996, The Journal of Biological Chemistry.

Oligodeoxynucleotides covalently linked to intercalating agents: a new class of gene regulatory substances.

J. Toulmé, C. Hélène, M. Takasugi, 1985, Biochimie.

Specific inhibition of mRNA translation by complementary oligonucleotides covalently linked to intercalating agents.

J. Toulmé, H. Krisch, C. Hélène, 1986, Proceedings of the National Academy of Sciences of the United States of America.

Enzymatic amplification of translation inhibition of rabbit beta-globin mRNA mediated by anti-messenger oligodeoxynucleotides covalently linked to intercalating agents.

J. Toulmé, C. Hélène, N. Thuong, 1987, Nucleic acids research.

An acridine-linked oligodeoxynucleotide targeted to the common 5' end of trypanosome mRNAs kills cultured parasites.

J. Toulmé, C. Hélène, N. Thuong, 1987, Gene.

A functional selection of viral genetic elements in cultured cells to identify hepatitis C virus RNA translation inhibitors†

J. Toulmé, C. Wychowski, C. Staedel, 2008, Nucleic acids research.

Deciphering aromatic oligoamide foldamer-DNA interactions.

J. Toulmé, Z. Dong, I. Huc, 2012, Angewandte Chemie.

Role of tryptophan and cysteine in the binding of gene 32 protein from phage T4 to single-stranded DNA. Modification of crucial residues by oxidation with selective free-radical anions

J. Toulmé, J. Casas-Finet, R. Santus, 1984 .

A tryptophan-containing peptide recognizes and cleaves DNA at apurinic sites

J. Toulmé, C. Hélène, T. Behmoaras, 1981, Nature.

QUENCHING OF TYROSINE FLUORESCENCE BY PHOSPHATE IONS: A MODEL STUDY FOR PROTEIN‐NUCLEIC ACID COMPLEXES

J. Toulmé, C. Hélène, T. Alev-Behmoaras, 1979 .

Oligonucleotide recognizing a nucleic acid sequence a nonlinear structure, application for therapeutic purposes and method of preparing

J. Toulmé, R. Mishra, 1994 .

Anti-pesticide DNA aptamers fail to recognize their targets with asserted micromolar dissociation constants.

E. Peyrin, J. Toulmé, Emmanuelle Fiore, 2021, Analytica chimica acta.

RNase H-mediated inhibition of translation by antisense oligodeoxyribonucleotides: use of backbone modification to improve specificity.

J. Toulmé, C. Blonski, D. Shire, 1992, Gene.

Effect of RNA secondary structure and modified bases on the inhibition of trypanosomatid protein synthesis in cell free extracts by antisense oligodeoxynucleotides.

J. Toulmé, D. Shire, N. Thuong, 1990, Nucleic acids research.

A phosphorothioate oligonucleotide blocks reverse transcription via an antisense mechanism

J. Toulmé, C. Boiziau, S. Moreau, 1994, FEBS letters.

Anti-messenger oligodeoxynucleotides: specific inhibition of rabbit beta-globin synthesis in wheat germ extracts and Xenopus oocytes.

J. Toulmé, N. Loreau, C. Cazenave, 1986, Biochimie.

Inhibition of translation initiation by antisense oligonucleotides via an RNase-H independent mechanism.

J. Toulmé, C. Boiziau, N. Thuong, 1991, Nucleic acids research.

Recognition of natural and chemically-damaged nucleic acids by peptides and proteins

J. Toulmé, T. Montenay-Garestier, C. Hélène, 1982 .

Quinazoline-2,4(1H,3H)-dione as a substitute for thymine in triple-helix forming oligonucleotides: a reassessment.

J. Toulmé, J. Vercauteren, S. Moreau, 1996, Nucleic acids research.

Comparative Analysis of Translation Efficiencies of Hepatitis C Virus 5′ Untranslated Regions among Intraindividual Quasispecies Present in Chronic Infection: Opposite Behaviors Depending on Cell Type

J. Toulmé, H. Agut, J. Pawlotsky, 2000, Journal of Virology.

A maximum of two tryptophan residues in gene-32 protein from phage T4 undergo stacking interactions with single-stranded polynucleotides.

J. Toulmé, J. Casas-Finet, R. Santus, 1988, European journal of biochemistry.

Stacking Interactions: The Key Mechanism for Binding of Proteins to Single-Stranded Regions of Native and Damaged Nucleic Acids?

J. Toulmé, 1985 .

Phosphoroselenoate oligodeoxynucleotides: synthesis, physico-chemical characterization, anti-sense inhibitory properties and anti-HIV activity.

J. Toulmé, S. Broder, C. Stein, 1989, Nucleic acids research.

Antimessenger oligodeoxyribonucleotides: an alternative to antisense RNA for artificial regulation of gene expression--a review.

J. Toulmé, C. Hélène, 1988, Gene.

4-amino-1H-benzo[g]quinazoline-2-one: a fluorescent analog of cytosine to probe protonation sites in triplex forming oligonucleotides.

J. Toulmé, S. Moreau, F. Godde, 2000, Nucleic acids research.

Recognition of chemically damaged DNA by the gene 32 protein from bacteriophage T4.

J. Toulmé, T. Behmoaras, C. Hélène, 1983, The EMBO journal.

Role of tryptophyl residues in the binding of gene 32 protein from phage T4 to single-stranded DNA. Photochemical modification of tryptophan by trichloroethanol

J. Toulmé, T. Doan, C. Hélène, 1984 .

Ribonuclease H : From Enzymes to Antisense Effects of Oligonucleotides

J. Toulmé, C. Boiziau, P. Frank, 1996 .

HIV-1interactions: RNA aptamers selective for the TAR RNA element of In vitro selection identifies key determinants for loop-loop

J. Toulmé, 1999 .

2'-O-methyl-RNA hairpins generate loop-loop complexes and selectively inhibit HIV-1 Tat-mediated transcription.

C. Di Primo, J. Toulmé, F. Darfeuille, 2002, Biochemistry.

Improved leishmanicidal effect of phosphorotioate antisense oligonucleotides by LDL-mediated delivery.

J. Toulmé, J. Bonnet, R. Mishra, 1995, Biochimica et biophysica acta.

Molecular dynamics reveals the stabilizing role of loop closing residues in kissing interactions: comparison between TAR-TAR* and TAR-aptamer.

C. Di Primo, J. Toulmé, M. Laguerre, 2003, Nucleic acids research.

Anti‐HIV Activity of Steric Block Oligonucleotides

A. Lever, J. Toulmé, S. Reigadas, 2006, Annals of the New York Academy of Sciences.

Driving in vitro selection of anti-HIV-1 TAR aptamers by magnesium concentration and temperature.

J. Toulmé, F. Darfeuille, C. Boiziau, 2002, Combinatorial chemistry & high throughput screening.

Modified oligonucleotides in rabbit reticulocytes: uptake, stability and antisense properties.

J. Toulmé, C. Boiziau, 1991, Biochimie.

Sensitive detection of low levels of ribonuclease H activity by an improved renaturation gel assay.

J. Toulmé, P. Frank, C. Cazenave, 1993, Biochemical and biophysical research communications.

Structure and Dynamics of Peptide-Nucleic Acid Complexes.

J. Toulmé, T. Doan, T. Montenay-Garestier, 1983 .

Interactions of aromatic residues of proteins with nucleic acids. Fluorescence studies of the binding of oligopeptides containing tryptophan and tyrosine residues to polynucleotides.

J. Toulmé, F. Brun, C. Hélène, 1975, Biochemistry.

Interaction of a tryptophan‐containing peptide with chromatin core particles

J. Toulmé, C. Hélène, Vincent Colot, 1984, FEBS letters.

Absorption and fluorescence studies of the binding of the recA gene product from E. coli to single-stranded and double-stranded DNA. Ionic strength dependence.

J. Toulmé, M. Chabbert, C. Cazenave, 1984, Biochimica et biophysica acta.

The recA Gene Product from E. coli . Binding to Single-Stranded and Double-Stranded DNA

J. Toulmé, M. Chabbert, C. Cazenave, 1983 .

Benzoquinazoline derivatives as substitutes for thymine in nucleic acid complexes. Use of fluorescence emission of benzo[g]quinazoline-2,4-(1H,3H)-dione in probing duplex and triplex formation.

J. Toulmé, J J Toulmé, F Godde, 1998, Biochemistry.

SELEX and dynamic combinatorial chemistry interplay for the selection of conjugated RNA aptamers.

J. Toulmé, B. Rayner, A. Bugaut, 2006, Organic & biomolecular chemistry.

Involvement of tryptophyl residues in the binding of model peptides and gene 32 protein from phage T4 to single-stranded polynucleotides. A spectroscopic method for detection of tryptophan in the vicinity of nucleic acid bases

J. Toulmé, T. Doan, C. Hélène, 1984 .

Stacking Interactions in Oligopeptide-Nucleic Acid Complexes

J. Toulmé, T. Doan, R. Mayer, 1981 .

RECOGNITION OF CHEMICALLY-DAMAGED DNA BY OLIGOPEPTIDES AND GENE 32 PROTEIN FROM PHAGE T4

J. Toulmé, C. Hélène, T. Alev-Behmoaras, 1980 .

Effect of phosphate ions on the fluorescence of tryptophan derivatives. Implications in fluorescence investigation of protein-nucleic acid complexes.

J. Toulmé, C. Hélène, T. Alev-Behmoaras, 1979, Biochimie.

Stacking interactions between aromatic amino acids and adenine ring of ATP in zinc mediated ternary complexes.

J. Toulmé, 1978, Bioinorganic chemistry.

Aptamers targeting RNA molecules.

J. Toulmé, B. Rayner, É. Dausse, 2009, Methods in molecular biology.

Modulation of RNA function by oligonucleotides recognizing RNA structure.

C. Di Primo, J. Toulmé, C. D. Primo, 2001, Progress in nucleic acid research and molecular biology.

Deciphering Aromatic Oligoamide Foldamer–DNA Interactions

J. Toulmé, Z. Dong, I. Huc, 2012 .

Specific recognition of apurinic sites in DNA by a tryptophan-containing peptide.

J. Toulmé, T. Behmoaras, C. Hélène, 1981, Proceedings of the National Academy of Sciences of the United States of America.

A spectroscopic probe of stacking interactions between nucleic acid bases and tryptophan residues of proteins.

J. Toulmé, T. Le Doan, C. Hélène, 1979, Nucleic acids research.

Specific recognition of single-stranded nucleic acids. Interaction of tryptophan-containing peptides with native, denatured, and ultraviolet-irradiated DNA.

J. Toulmé, C. Hélène, 1977, The Journal of biological chemistry.

Specific recognition of single-stranded regions in ultraviolet-irradiated and heat-denatured DNA by tryptophan-containing peptides.

J. Toulmé, M. Charlier, C. Hélène, 1974, Proceedings of the National Academy of Sciences of the United States of America.

Specific recognition by the tripeptide lysyl-tryptophyl-alpha-lysine of structural damage induced in DNA by platinum derivatives.

J. Toulmé, T. Le Doan, C. Hélène, 1985, Biochimica et biophysica acta.

Recognition of damaged regions in DNA by oligopeptides and proteins.

J. Toulmé, T. Saison-Behmoaras, 1985, Biochimie.

Influence of DNA binding on the formation and reactions of tryptophan and tyrosine radicals in peptides and proteins.

J. Toulmé, E. Land, J. Casas-Finet, 1984, International journal of radiation biology and related studies in physics, chemistry, and medicine.

Mechanisms for the recognition of chemically-modified DNA by peptides and proteins.

J. Toulmé, C. Cazenave, T. Behmoaras, 1982, Biochimie.

Fluorescence study of the association between gene 32 protein of bacteriophage T4 and poly(1-N6-ethenoadenylic acid). Evidence for energy transfer.

J. Toulmé, C. Hélène, 1980, Biochimica et biophysica acta.

PHOTOSENSITIZED SPLITTING OF THYMINE DIMERS IN DNA BY PEPTIDES AND PROTEIN CONTAINING TRYPTOPHANYL RESIDUES

J. Toulmé, M. Charlier, F. Toulmé, 1978 .

Towards the selection of phosphorothioate aptamers

J. Toulmé, C. Calmels, M. Andreola, 2000 .

Towards the selection of phosphorothioate aptamers optimizing in vitro selection steps with phosphorothioate nucleotides.

J. Toulmé, C. Calmels, M. Andreola, 2000, European journal of biochemistry.

Specific regulation of gene expression by antisense, sense and antigene nucleic acids.

J. Toulmé, C Hélène, J J Toulmé, 1990, Biochimica et biophysica acta.

The binding of an antisense oligonucleotide to a hairpin structure via triplex formation inhibits chemical and biological reactions.

J. Toulmé, E. Pascolo, E. Brossalina, 1993, Nucleic acids research.

A DNA hairpin as a target for antisense oligonucleotides

J. Toulmé, E. Brossalina, 1993 .

A malachite green light-up aptasensor for the detection of theophylline.

J. Toulmé, É. Dausse, L. Zara, 2021, Talanta.

Aptamers: Ligands For All Reasons

Jean-Jacques Toulmé, Jean‐Pierre Daguer, Eric Dausse, 2008 .

Modulating viral gene expression by aptamers to RNA structures

J. Toulmé, C. Staedel, F. Darfeuille, 2003, Biology of the cell.

Antisense oligonucleotides targeted to the domain IIId of the hepatitis C virus IRES compete with 40S ribosomal subunit binding and prevent in vitro translation.

J. Toulmé, C. Staedel, É. Dausse, 2003, Nucleic acids research.

The common 5' terminal sequence on trypanosome mRNAs: a target for anti-messenger oligodeoxynucleotides.

J. Toulmé, P. Borst, B. Swinkels, 1986, Nucleic acids research.

Relative contribution of photo-addition, helper oligonucleotide and RNase H to the antisense effect of psoralen-oligonucleotide conjugates, on in vitro translation of Leishmania mRNAs.

J. Toulmé, B. Sproat, T. Nguyen, 1994, Biochimica et biophysica acta.

Effect of Antisense Oligonucleotides Linked to Alkylating Agents on In Vitro Translation of Rabbit β-Globin and Typuaosomu brucei mRNAs

J. Toulmé, C. Boiziau, A. Boutorine, 1991 .

Control of Gene Expression by Oligodeoxynucleotides Covalently Linked to Intercalating Agents and Nucleic Acid-cleaving Reagents

J. Toulmé, C. Hélène, 1989 .

Antisense Oligonucleotides Containing Modified Bases Inhibit in Vitro Translation of Leishmania amazonensis mRNAs by Invading the Mini-exon Hairpin*

J. Toulmé, E. Lukhtanov, H. Gamper, 1999, The Journal of Biological Chemistry.

Control of gene expression in viruses and protozoan parasites by antisense oligonucleotides

J. Toulmé, L. Yurchenko, D. Compagno, 1997, Parasitology.

Targeting RNA structures by antisense oligonucleotides.

J. Toulmé, E. Brossalina, R. L. Tinévez, 1996, Biochimie.

Antisense effect of oligodeoxynucleotides complementary to the mini-exon sequence of the protozoan parasite Leishmania amazonensis.

J. Toulmé, C. Blonski, D. Shire, 1993, Biochimie.

Blockage of AM V reverse transcriptase by antisense oligodeoxynucleotides

J. Toulmé, D. Shire, C. Boiziau, 1990, FEBS letters.

Comparative inhibition of rabbit globin mRNA translation by modified antisense oligodeoxynucleotides.

J. Toulmé, L. Neckers, J. S. Cohen, 1989, Nucleic acids research.

Effect of the terminal phosphate derivatization of β- and α-oligodeoxynucleotides on their antisense activity in protein biosynthesis, stability and uptake by eucaryotic cells

J. Toulmé, T. Doan, C. Boiziau, 1992 .

Selective inhibition of cell-free translation by oligonucleotides targeted to a mRNA hairpin structure.

J. Toulmé, R. Mishra, R. Le Tinévez, 1998, Nucleic acids research.

Artificial regulation of gene expression by complementary oligonucleotides : an overview

J. Toulmé, 1992 .

Chimeric alpha‐beta oligonucleotides as antisense inhibitors of reverse transcription

J. Toulmé, C. Boiziau, B. Rayner, 1995, FEBS letters.

Antisense oligonucleotides inhibit in vitro cDNA synthesis by HIV-1 reverse transcriptase.

J. Toulmé, C. Boiziau, L. Tarrago-Litvak, 1996, Antisense & nucleic acid drug development.

Antisense phosphorothioate oligonucleotides: selective killing of the intracellular parasite Leishmania amazonensis.

J. Toulmé, Raghvendra Kumar Mishra, S. Moreau, 1994, Proceedings of the National Academy of Sciences of the United States of America.

Antisense effects of oligonucleotides complementary to the hairpin of the Leishmania mini-exon RNA.

J. Toulmé, D. Compagno, 1999, Nucleosides and Nucleotides.

Cleavage of Leishmania Mini-exon Sequence by Oligonucleotides Conjugated to a Dimidazole Construction

J. Toulmé, V. Vlassov, V. Silnikov, 1997 .

Oligodeoxynucleotides covalently linked to intercalating agents: a new family of gene regulatory substances.

J. Toulmé, J. Maurizot, U. Asseline, 1986, Biochemical Society Transactions.

Gel renaturation assay for ribonucleases.

J. Toulmé, C. Cazenave, 2001, Methods in enzymology.

Modified (PNA, 2'-O-methyl and phosphoramidate) anti-TAR antisense oligonucleotides as strong and specific inhibitors of in vitro HIV-1 reverse transcription.

J. Toulmé, P. Nielsen, S. Litvak, 1998, Nucleic acids research.

Binding of oligopyrimidines to the RNA hairpin responsible for the ribosome gag‐pol frameshift in HIV‐1

J. Toulmé, K. Aupeix, R. Le Tinévez, 1999, FEBS letters.

Antisense 2'-O-alkyl oligoribonucleotides are efficient inhibitors of reverse transcription

Claudine Boiziau, Jean-Jacques Toulmé, Béatrice Larrouy, 1995, Nucleic Acids Res..

Mechanisms of the inhibition of reverse transcription by antisense oligonucleotides.

J. Toulmé, C. Boiziau, N. Thuong, 1992, Proceedings of the National Academy of Sciences of the United States of America.

Identification of aptamers against the DNA template for in vitro transcription of the HIV-1 TAR element.

F. Ducongé, J. Toulmé, C. Boiziau, 1997, Antisense & nucleic acid drug development.

Targeting nucleic acid secondary structures by antisense oligonucleotides designed through in vitro selection.

J. Toulmé, R. Mishra, R. Le Tinévez, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Selective inhibitory DNA aptamers of the human RNase H1.

Jean-Jacques Toulmé, Eric Dausse, J. Toulmé, 2003, Nucleic acids research.

Aptamers: Analytical Tools for Viral Components

J. Toulmé, L. Azéma, É. Dausse, 2013 .

In vitro selection of DNA aptamers against the HIV-1 TAR RNA hairpin.

C. Di Primo, J. Toulmé, F. Darfeuille, 2002, Antisense & nucleic acid drug development.

Comparative Studies of Tricyclo-DNA- and LNA-Containing Oligonucleotides as Inhibitors of HIV-1 Gene Expression

J. Toulmé, D. Ittig, C. Leumann, 2007, Nucleosides, nucleotides & nucleic acids.

Tricyclo-DNA containing oligonucleotides as steric block inhibitors of human immunodeficiency virus type 1 tat-dependent trans-activation and HIV-1 infectivity.

J. Toulmé, D. Ittig, C. Leumann, 2007, Oligonucleotides.

In vitro selection procedures for identifying DNA and RNA aptamers targeted to nucleic acids and proteins.

J. Toulmé, B. Rayner, É. Dausse, 2005, Methods in molecular biology.

Characterization and subcellular localization of ribonuclease H activities from Xenopus laevis oocytes.

J. Toulmé, P. Frank, C. Cazenave, 1994, The Journal of biological chemistry.

Purification and characterization of human ribonuclease HII.

J. Toulmé, P. Frank, C. Cazenave, 1994, Nucleic acids research.

RNase H is responsible for the non-specific inhibition of in vitro translation by 2'-O-alkyl chimeric oligonucleotides: high affinity or selectivity, a dilemma to design antisense oligomers.

J. Toulmé, B. Sproat, C. Boiziau, 1995, Nucleic acids research.

New Ways of Initiating Translation in Eukaryotes?

M. Hentze, R. Jackson, O. Elroy-Stein, 2001, Molecular and Cellular Biology.

Aptamers targeted to an RNA hairpin show improved specificity compared to that of complementary oligonucleotides.

C. Di Primo, J. Toulmé, F. Darfeuille, 2006, Biochemistry.

Binding of RecA protein to single‐stranded nucleic acids: spectroscopic studies using fluorescent polynucleotides.

J. Toulmé, C. Cazenave, C. Hélène, 1983, The EMBO journal.

DNA aptamers selected against the HIV-1 RNase H display in vitro antiviral activity.

J. Toulmé, C. Calmels, M. Andreola, 2001, Biochemistry.

Liquid-crystal NMR structure of HIV TAR RNA bound to its SELEX RNA aptamer reveals the origins of the high stability of the complex

David L Bryce, Jean-Jacques Toulmé, J. Boisbouvier, 2008, Proceedings of the National Academy of Sciences.

Loop–loop interaction of HIV-1 TAR RNA with N3′ → P5′ deoxyphosphoramidate aptamers inhibits in vitro Tat-mediated transcription

C. Di Primo, J. Toulmé, F. Darfeuille, 2002, Proceedings of the National Academy of Sciences of the United States of America.

A method to select chemically modified aptamers directly.

J. Toulmé, C. Boiziau, 2001, Antisense & nucleic acid drug development.

Apical loop-internal loop interactions: a new RNA-RNA recognition motif identified through in vitro selection against RNA hairpins of the hepatitis C virus mRNA.

Jean-Jacques Toulmé, Eric Dausse, J. Toulmé, 2002, Biochemistry.

New candidates for true antisense

J. Toulmé, 2001, Nature Biotechnology.

HAPIscreen, a method for high-throughput aptamer identification

Eric Chevet, Jean-Jacques Toulmé, Eric Dausse, 2011, Journal of nanobiotechnology.

Aptamers as imaging agents.

M. Allard, J. Toulmé, L. Azéma, 2010, Expert opinion on medical diagnostics.

Aptamers: a new class of oligonucleotides in the drug discovery pipeline?

J. Toulmé, É. Dausse, Sonia Da Rocha Gomes, 2009, Current opinion in pharmacology.

Understanding the Translation Regulatory Mechanisms to Improve the Efficiency and the Specificity of Protein Production by the Cell Factory

J. Toulmé, A. Prats, H. Prats, 1999 .

DARK INTERACTION AND OXYGEN DEPENDENT PHOTOBINDING BETWEEN AN AROMATIC TETRAPEPTIDE AND DNA MODIFIED BY 5‐ METHOXYPSORALEN MONOADDUCTS

J. Toulmé, L. Dubertret, P. Morlière, 1986, Photochemistry and photobiology.

Inhibition of Pre-mRNA Splicing by a Synthetic Blom7α-Interacting Small RNA

J. Toulmé, A. Lamond, M. Schosserer, 2012, PloS one.

Encapsidation of RNA-polyelectrolyte complexes with amphiphilic block copolymers: toward a new self-assembly route.

J. Toulmé, C. Staedel, S. Lecommandoux, 2012, Journal of the American Chemical Society.

Single-strand binding proteins from phage T4 and E. coli form higher order structures with poly(dT).

J. Toulmé, T. Saison-Behmoaras, C. Hélène, 1986, Biochimie.

THE PHOTOPHYSICAL AND PHOTOCHEMICAL PROCESSES OF TRYPTOPHAN IN INTERACTION WITH POLYNUCLEOTIDES: LASER FLASH PHOTOLYSIS STUDY

J. Toulmé, R. Santus, T. Doan, 1981 .

Eukaryotic ribonucleases HI and HII generate characteristic hydrolytic patterns on DNA-RNA hybrids: further evidence that mitochondrial RNase H is an RNase HII.

J. Toulmé, F. Pileur, C. Cazenave, 2000, Nucleic Acids Research.

Design of a dual aptamer-based recognition strategy for human matrix metalloproteinase 9 protein by piezoelectric biosensors.

J. Toulmé, M. Minunni, S. Scarano, 2015, Analytica chimica acta.

In vitro selection identifies key determinants for loop-loop interactions: RNA aptamers selective for the TAR RNA element of HIV-1.

F. Ducongé, J. Toulmé, Frédéric Ducongé, 1999, RNA.

Nucleic acids targeted to drugs: SELEX against a quadruplex ligand.

Jean-Louis Mergny, Jean-Jacques Toulmé, Eric Dausse, 2011, Biochimie.

Effect of the terminal phosphate derivatization of beta- and alpha-oligodeoxynucleotides on their antisense activity in protein biosynthesis, stability and uptake by eucaryotic cells.

J. Toulmé, C. Boiziau, A. Boutorine, 1992, Biochimie.

(99m)Tc-MAG3-aptamer for imaging human tumors associated with high level of matrix metalloprotease-9.

M. Allard, J. Toulmé, L. Azéma, 2012, Bioconjugate chemistry.

A combinatorial approach to the repertoire of RNA kissing motifs; towards multiplex detection by switching hairpin aptamers

E. Peyrin, J. Toulmé, Emmanuelle Fiore, 2016, Nucleic acids research.

Regulating eukaryotic gene expression with aptamers

Jean-Jacques Toulmé, C. Di Primo, J. Toulmé, 2004, FEBS letters.

LNA derivatives of a kissing aptamer targeted to the trans-activating responsive RNA element of HIV-1.

C. Di Primo, J. Toulmé, I. Lebars, 2007, Blood cells, molecules & diseases.

ELAKCA: Enzyme-Linked Aptamer Kissing Complex Assay as a Small Molecule Sensing Platform.

E. Peyrin, J. Toulmé, C. Ravelet, 2016, Analytical chemistry.

In vitro selection of RNA aptamers derived from a genomic human library against the TAR RNA element of HIV-1.

J. Toulmé, R. Schroeder, É. Dausse, 2009, Biochemistry.

Aptamer selection by direct microfluidic recovery and surface plasmon resonance evaluation.

M. Nikolski, C. Di Primo, J. Toulmé, 2016, Biosensors & bioelectronics.

Advances in binder identification and characterisation: the case of oligonucleotide aptamers.

Eric Chevet, Jean-Jacques Toulmé, Eric Dausse, 2012, New biotechnology.

Aptamers in Bordeaux 2017: An exceptional "millésime".

Jean-Jacques Toulmé, Eric Dausse, Laurent Azéma, 2017, Biochimie.

Hexitol nucleic acid-containing aptamers are efficient ligands of HIV-1 TAR RNA.

J. Toulmé, P. Herdewijn, A. Van Aerschot, 2005, Biochemistry.

Surface plasmon resonance investigation of RNA aptamer-RNA ligand interactions.

C. Di Primo, J. Toulmé, É. Dausse, 2011, Methods in molecular biology.

Mapping of a Minimal AU-rich Sequence Required for Lipopolysaccharide-induced Binding of a 55-kDa Protein on Tumor Necrosis Factor-α mRNA*

J. Toulmé, V. Kruys, G. Huez, 1998, The Journal of Biological Chemistry.

Triggering nucleic acid nanostructure assembly by conditional kissing interactions

J. Toulmé, L. Azéma, H. Sugiyama, 2017, Nucleic acids research.

A colorimetric nanosensor based on a selective target-responsive aptamer kissing complex.

E. Peyrin, J. Toulmé, L. Azéma, 2017, Nanoscale.

Oligonucleotide solid-phase synthesis on fluorescent nanoparticles grafted on controlled pore glass{

J. Toulmé, M. Janier, Gabriel De Crozals, 2012 .

Determinants of apical loop-internal loop RNA-RNA interactions involving the HCV IRES.

J. Toulmé, É. Dausse, Sonia Da Rocha Gomes, 2004, Biochemical and biophysical research communications.

Title Triggering nucleic acid nanostructure assembly by conditionalkissing interactions

J. Toulmé, L. Azéma, H. Sugiyama, 2018 .

An improved design of the kissing complex-based aptasensor for the detection of adenosine

E. Peyrin, J. Toulmé, S. Lisi, 2015, Analytical and Bioanalytical Chemistry.

In vitro selection of RNA aptamers derived from a genomic human library against the TAR RNA element of HIV-1.

J. Toulmé, R. Schroeder, É. Dausse, 2009, Biochemistry.

Advances in binder identification and characterisation: the case of oligonucleotide aptamers.

C. Di Primo, J. Toulmé, É. Dausse, 2012, New biotechnology.

Aptamer-mediated nanoparticle interactions: from oligonucleotide-protein complexes to SELEX screens.

J. Toulmé, É. Dausse, S. Taouji, 2015, Methods in molecular biology.

Liquid-crystal NMR structure of HIV TAR RNA bound to its SELEX RNA aptamer reveals the origins of the high stability of the complex

J. Boisbouvier, C. Di Primo, J. Toulmé, 2008, Proceedings of the National Academy of Sciences.

RNA AND N3′ → P5′ KISSING APTAMERS TARGETED TO THE TRANS-ACTIVATION RESPONSIVE (TAR) RNA OF THE HUMAN IMMUNODEFICIENCY VIRUS-1

F. Ducongé, C. Di Primo, J. Toulmé, 2001 .

Systematic screening of LNA/2′‐O‐methyl chimeric derivatives of a TAR RNA aptamer

C. Di Primo, J. Toulmé, S. Reigadas, 2007, FEBS letters.

Endogenous Expression of an Anti-TAR Aptamer Reduces HIV-1 Replication

J. Toulmé, J. Rossi, D. Castanotto, 2006, RNA biology.

Aptamers: selected oligonucleotides for therapy.

J. Toulmé, 2000, Current opinion in molecular therapeutics.