J. Ervasti

J. Ervasti, K. Prins, Kevin J. Sonnemann, 2009, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Transgenic overexpression of γ-cytoplasmic actin protects against eccentric contraction-induced force loss in mdx mice

J. Ervasti, D. Lowe, K. Baltgalvis, 2011, Skeletal Muscle.

Stem Cell-Derived Cardiomyocytes and Beta-Adrenergic Receptor Blockade in Duchenne Muscular Dystrophy Cardiomyopathy.

Jianyi(Jay) Zhang, J. Ervasti, T. Kamp, 2020, Journal of the American College of Cardiology.

contractionsin mouse EDL muscle after eccentric 2+ Temperature dependency of force loss and Ca

J. Ervasti, Gordon L Warren, D. Lowe, 2013 .

Pax3-induced expansion enables the genetic correction of dystrophic satellite cells

M. Kyba, R. Perlingeiro, J. Ervasti, 2015, Skeletal Muscle.

Neopterin/7,8‐dihydroneopterin is elevated in Duchenne muscular dystrophy patients and protects mdx skeletal muscle function

J. Ervasti, A. Lindsay, Christopher M. Chamberlain, 2018, Experimental physiology.

The Dystrophin Complex Forms a Mechanically Strong Link between the Sarcolemma and Costameric Actin

J. Ervasti, I. Rybakova, J. R. Patel, 2000, The Journal of cell biology.

Dystrophin missense mutations alter focal adhesion tension and mechanotransduction

J. Ervasti, D. Odde, Lauren J Sundby, 2022, Proceedings of the National Academy of Sciences of the United States of America.

Dystrophin and utrophin have distinct effects on the structural dynamics of actin

J. Ervasti, David D. Thomas, E. Próchniewicz, 2009, Proceedings of the National Academy of Sciences.

Destabilization of the Dystrophin-Glycoprotein Complex without Functional Deficits in α-Dystrobrevin Null Muscle

J. Ervasti, K. Prins, D. Fitzsimons, 2008, PloS one.

Skeletal Muscle-Specific Ablation of γcyto-Actin Does Not Exacerbate the mdx Phenotype

J. Ervasti, D. Lowe, K. Prins, 2008, PloS one.

Cytoplasmic γ-actin expression in diverse animal models of muscular dystrophy

J. Ervasti, J. Kornegay, D. Bogan, 2007, Neuromuscular Disorders.

Isometric resistance training increases strength and alters histopathology of dystrophin-deficient mouse skeletal muscle.

J. Ervasti, A. Lindsay, D. Lowe, 2019, Journal of applied physiology.

Nucleotide- and Protein-Dependent Functions of Actg1

J. Ervasti, W. M. Southern, B. Perrin, 2022, Molecular biology of the cell.

Multi-isotope imaging mass spectrometry (MIMS) reveals slow protein turnover in hair-cell stereocilia

David P. Corey, Valeria Piazza, J. Collin Poczatek, 2011, Nature.

Enhancing interaction of actin and actin-binding domain 1 of dystrophin with modulators: Toward improved gene therapy for Duchenne muscular dystrophy

Joseph M. Muretta, J. Ervasti, Andrew R. Thompson, 2022, The Journal of biological chemistry.

Dystrophin and Utrophin Bind Actin through Distinct Modes of Contact*

Jill L. Humston, J. Ervasti, I. Rybakova, 2006, Journal of Biological Chemistry.

Association of dystrophin-related protein with dystrophin-associated proteins in mdx mouse muscle

J. Ervasti, K. Campbell, S. D. Kahl, 1992, Nature.

Brain α‐dystroglycan displays unique glycoepitopes and preferential binding to laminin‐10/11

Erin L. McDearmon, J. Ervasti, K. Sekiguchi, 2006 .

Tissue-specific heterogeneity in alpha-dystroglycan sialoglycosylation. Skeletal muscle alpha-dystroglycan is a latent receptor for Vicia villosa agglutinin b4 masked by sialic acid modification.

J. Ervasti, A. Geissler, A. L. Burwell, 1997, The Journal of biological chemistry.

A role for the dystrophin-glycoprotein complex as a transmembrane linker between laminin and actin

J. Ervasti, K. Campbell, 1993, The Journal of cell biology.

Isometric resistance training increases strength and alters histopathology of dystrophin-deficient 1 mouse skeletal muscle 2 3 Short Title : Isometric training in mdx mice 4 5

J. Ervasti, A. Lindsay, D. Lowe, 2018 .

Postanesthetic Death in a Cat With Myopathy

D. W. Hayden, J. Ervasti, S. Valberg, 2015, Veterinary pathology.

β-Actin specifically controls cell growth, migration, and the G-actin pool

J. Ervasti, Y. Shimizu, B. Burbach, 2011, Molecular biology of the cell.

Loss of β-Cytoplasmic Actin in the Intestinal Epithelium Increases Gut Barrier Permeability in vivo and Exaggerates the Severity of Experimental Colitis

J. Ervasti, A. Ivanov, S. Lechuga, 2020, Frontiers in Cell and Developmental Biology.

The Actin Gene Family: Function Follows Isoform

J. Ervasti, B. Perrin, 2010, Cytoskeleton.

Loss of peroxiredoxin-2 exacerbates eccentric contraction-induced force loss in dystrophin-deficient muscle

J. Ervasti, Dae-Yeul Yu, D. Garry, 2018, Nature Communications.

Restricted Morphological and Behavioral Abnormalities following Ablation of β-Actin in the Brain

J. Ervasti, Thomas R. Cheever, Bin Li, 2012, PloS one.

Delayed embryonic development and impaired cell growth and survival in Actg1 null mice

J. Ervasti, Tina M. Bunnell, 2010, Cytoskeleton.

The ZZ Domain of Dystrophin in DMD: Making Sense of Missense Mutations

K. Flanigan, J. Ervasti, A. Vulin, 2014, Human mutation.

Disease-causing missense mutations in actin binding domain 1 of dystrophin induce thermodynamic instability and protein aggregation

J. Ervasti, Ann S. G. Lee, D. Henderson, 2010, Proceedings of the National Academy of Sciences.

Independent variability of microtubule perturbations associated with dystrophinopathy.

J. Ervasti, G. Gundersen, Christopher M. Chamberlain, 2016, Human molecular genetics.

Membrane organization of the dystrophin-glycoprotein complex

J. Ervasti, K. Campbell, 1991, Cell.

Cytoplasmic gamma-actin contributes to a compensatory remodeling response in dystrophin-deficient muscle.

J. Ervasti, J. Rafael-Fortney, Laurin M Hanft, 2006, Proceedings of the National Academy of Sciences of the United States of America.

A Cluster of Basic Repeats in the Dystrophin Rod Domain Binds F-actin through an Electrostatic Interaction*

J. Ervasti, K. J. Amann, James M. Ervasti, 1998, The Journal of Biological Chemistry.

Dystrophin-Glycoprotein Complex Is Monomeric and Stabilizes Actin Filaments in Vitro through a Lateral Association*

J. Ervasti, I. Rybakova, 1997, The Journal of Biological Chemistry.

A new model for the interaction of dystrophin with F-actin

J. Ervasti, K. J. Amann, I. Rybakova, 1996, The Journal of cell biology.

Dystrophin-glycoprotein complex and laminin colocalize to the sarcolemma and transverse tubules of cardiac muscle.

J. Ervasti, K. Campbell, A. O. Jorgensen, 1993, Circulation research.

Dystrophin-glycoprotein complex is highly enriched in isolated skeletal muscle sarcolemma

J. Ervasti, K. Campbell, K. Ohlendieck, 1991, The Journal of cell biology.

Dystrophin: A Multifaceted Protein Critical for Muscle Health

J. Ervasti, D. Nelson, 2020 .

The carboxy-terminal third of dystrophin enhances actin binding activity.

J. Ervasti, David D. Thomas, D. Henderson, 2012, Journal of molecular biology.

Biology of the striated muscle dystrophin-glycoprotein complex.

J. Ervasti, Kevin J. Sonnemann, 2008, International review of cytology.

Dystrophin, its interactions with other proteins, and implications for muscular dystrophy.

J. Ervasti, 2007, Biochimica et biophysica acta.

Binding of dystrophin's tandem calponin homology domain to F-actin is modulated by actin's structure.

J. Ervasti, E. Egelman, D. D. Thomas, 2001, Biophysical journal.

Microtubule binding distinguishes dystrophin from utrophin

J. Ervasti, D. Lowe, Joseph J. Belanto, 2014, Proceedings of the National Academy of Sciences.

The dystrophin-glycoprotein complex: identification and biochemical characterization

J. Ervasti, K. Campbell, K. Ohlendieck, 1991 .

Deficiency of a glycoprotein component of the dystrophin complex in dystrophic muscle

J. Ervasti, K. Campbell, K. Ohlendieck, 1990, Nature.

Dystrophin As a Molecular Shock Absorber.

J. Ervasti, Jie Yan, Zhihai Zhao, 2018, ACS nano.

In vitro stability of therapeutically relevant, internally truncated dystrophins

J. Ervasti, Joseph J. Belanto, Jackie L. McCourt, 2015, Skeletal Muscle.

High Frequency Hearing Loss and Hyperactivity in DUX4 Transgenic Mice

M. Kyba, J. Ervasti, A. Bartolomucci, 2016, PloS one.

Contraction-Induced Loss of Plasmalemmal Electrophysiological Function Is Dependent on the Dystrophin Glycoprotein Complex

J. Ervasti, A. Lindsay, D. Lowe, 2021, Frontiers in Physiology.

Corrigendum: Persistent upregulation of the β-tubulin tubb6, linked to muscle regeneration, is a source of microtubule disorganization in dystrophic muscle.

A. Mammen, J. Ervasti, D. Sackett, 2019, Human molecular genetics.

Persistent upregulation of the &bgr;‐tubulin tubb6, linked to muscle regeneration, is a source of microtubule disorganization in dystrophic muscle

A. Mammen, J. Ervasti, D. Sackett, 2018, Human molecular genetics.

Regional vulnerability in a neurodegenerative disease: Delineating SCA1 CNS and muscle therapeutic targets using a conditional mutant ATXN1 mouse.

Jason S. Mitchell, H. Zoghbi, J. Ervasti, 2023, bioRxiv : the preprint server for biology.

β-Actin and Fascin-2 Cooperate to Maintain Stereocilia Length

J. Ervasti, K. Johnson, B. Perrin, 2013, The Journal of Neuroscience.

γ-Actin is required for cytoskeletal maintenance but not development

J. Ervasti, J. McGee, E. Walsh, 2009, Proceedings of the National Academy of Sciences.

Structural and functional properties of the actin gene family.

J. Ervasti, Tina M. Bunnell, 2011, Critical reviews in eukaryotic gene expression.

Relative importance of βcyto- and γcyto-actin in primary mouse embryonic fibroblasts

J. Ervasti, B. Moriarity, Christopher M. Chamberlain, 2017, Molecular biology of the cell.

Purification of dystrophin from skeletal muscle.

J. Ervasti, K. Campbell, S. Kahl, 1991, The Journal of biological chemistry.

Internal deletion compromises the stability of dystrophin.

J. Ervasti, Joseph J. Belanto, D. Henderson, 2011, Human molecular genetics.

Expression of Dp260 in muscle tethers the actin cytoskeleton to the dystrophin-glycoprotein complex and partially prevents dystrophy.

J. Ervasti, J. Chamberlain, C. Dellorusso, 2002, Human molecular genetics.

Utrophin Lacks the Rod Domain Actin Binding Activity of Dystrophin*

J. Ervasti, K. J. Amann, Athena W.-X. Guo, 1999, The Journal of Biological Chemistry.

Dystrophin and the membrane skeleton.

J. Ervasti, K. Campbell, Kevin P. Campbell, 1993, Current opinion in cell biology.

Deficiency of dystrophin-associated proteins in Duchenne muscular dystrophy patients lacking COOH-terminal domains of dystrophin.

J. Ervasti, K. Campbell, N. Romero, 1993, The Journal of clinical investigation.

Results Characterization of Dystrophin-- Glycoprotein Complex Binding to F-Actin

J. Ervasti, K. J. Amann, N. Rybakova, 2002 .

Identification of New Dystroglycan Complexes in Skeletal Muscle

K. Flanigan, J. Ervasti, F. Montanaro, 2013, PloS one.

J. Ervasti, C. Leveille, K. Campbell, 1991, Neuron.

Phosphorylation alters the mechanical stiffness of a model fragment of the dystrophin homologue utrophin

Joseph M. Muretta, J. Ervasti, M. Salapaka, 2022, The Journal of biological chemistry.

Integrative effects of dystrophin loss on metabolic function of the mdx mouse

Daniel J. Garry, J. Straková, J. Ervasti, 2018, Scientific Reports.

Disruption of the dystrophin-glycoprotein complex in the cardiomyopathic hamster.

J. Ervasti, K. Campbell, S. Roberds, 1993, The Journal of biological chemistry.

Differential Vicia villosa Agglutinin Reactivity Identifies Three Distinct Dystroglycan Complexes in Skeletal Muscle*

Erin L. McDearmon, J. Ervasti, Ariana C. Combs, 2001, The Journal of Biological Chemistry.

Differential Heparin Sensitivity of α-Dystroglycan Binding to Laminins Expressed in Normal and dy/dy Mouse Skeletal Muscle*

Erin L. McDearmon, J. Ervasti, Ariana C. Combs, 1998, The Journal of Biological Chemistry.

Tissue-specific Heterogeneity in α-Dystroglycan Sialoglycosylation

J. Ervasti, A. Geissler, A. L. Burwell, 1997, The Journal of Biological Chemistry.

Differential Heparin Inhibition of Skeletal Muscle -Dystroglycan Binding to Laminins (*)

J. Ervasti, Elizabeth A. Pall, Kevin M. Bolton, 1996, The Journal of Biological Chemistry.

α‐Dystroglycan deficiency correlates with elevated serum creatine kinase and decreased muscle contraction tension in golden retriever muscular dystrophy

J. Ervasti, K. Campbell, S. Roberds, 1994, FEBS letters.

Dystrophin-associated glycoproteins: their possible roles in the pathogenesis of Duchenne muscular dystrophy.

J. Ervasti, K. Campbell, Kevin P. Campbell, 1993, Molecular and cell biology of human diseases series.

Domestic Animals – Diagnostic Exercise Postanesthetic Death in a Cat With Myopathy

D. W. Hayden, J. Ervasti, S. Valberg, 2014 .

Mouse models of two missense mutations in actin-binding domain 1 of dystrophin associated with Duchenne or Becker muscular dystrophy

M. Kyba, J. Ervasti, A. Lindsay, 2018, Human molecular genetics.

Disease-proportional proteasomal degradation of missense dystrophins

J. Ervasti, Joseph J. Belanto, Dana M Talsness, 2015, Proceedings of the National Academy of Sciences.

Variable cytoplasmic actin expression impacts the sensitivity of different dystrophin‐deficient mdx skeletal muscles to eccentric contraction

J. Ervasti, W. M. Southern, James S. Hodges, 2019, The FEBS journal.

Tubules of Cardiac Muscle

J. Ervasti, K. Campbell, 0., 2005 .

The utrophin actin-binding domain binds F-actin in two different modes

Edward H. Egelman, Vitold E. Galkin, J. Ervasti, 2002, The Journal of cell biology.

Some dystrophy phenotypes of dystrophin‐deficient mdx mice are exacerbated by mild, repetitive daily stress

J. Ervasti, A. Bartolomucci, A. Lindsay, 2021, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Rapid, redox-mediated mechanical susceptibility of the cortical microtubule lattice in skeletal muscle

J. Ervasti, A. Lindsay, D. Lowe, 2020, Redox biology.

Mechanical factors tune the sensitivity of mdx muscle to eccentric strength loss and its protection by antioxidant and calcium modulators

J. Hodges, J. Ervasti, David D. Thomas, 2020, Skeletal Muscle.

Distinct mechanical properties in homologous spectrin-like repeats of utrophin

J. Ervasti, Sayan Ghosal, M. Salapaka, 2019, Scientific Reports.

Crystal Structure and Cell Surface Anchorage Sites of Laminin α1LG4-5*

J. Ervasti, E. Hohenester, S. Hussain, 2007, Journal of Biological Chemistry.

A multiple site, side binding model for the interaction of dystrophin with F-actin.

J. Ervasti, K. J. Amann, I. Rybakova, 1997, Society of General Physiologists series.

Site Mapping and Characterization of O-Glycan Structures on α-Dystroglycan Isolated from Rabbit Skeletal Muscle*

J. Ervasti, K. Aoki, L. Wells, 2010, The Journal of Biological Chemistry.

Actin Is Crucial for All Kinetically Distinguishable Forms of Endocytosis at Synapses

J. Ervasti, Sung Hoon Lee, Xin-sheng Wu, 2016, Neuron.

PFKFB3-mediated glycolysis rescues myopathic outcomes in the ischemic limb

P. Neufer, J. Ervasti, Terence E. Ryan, 2020, JCI insight.

Essential nucleotide- and protein-dependent functions of Actb/β-actin

D. Voytas, J. Ervasti, A. Lindsay, 2018, Proceedings of the National Academy of Sciences.

β-Actin and γ-Actin Are Each Dispensable for Auditory Hair Cell Development But Required for Stereocilia Maintenance

J. Ervasti, B. Perrin, Kevin J. Sonnemann, 2010, PLoS genetics.

Crystal structure and cell surface anchorage sites of laminin alpha1LG4-5.

J. Ervasti, E. Hohenester, S. Hussain, 2007, The Journal of biological chemistry.

In vitro stability of therapeutically relevant, internally truncated dystrophins

J. Ervasti, Joseph J. Belanto, Jackie L. McCourt, 2015, Skeletal Muscle.

Delineating regional vulnerability in the neurodegenerative disease SCA1 using a conditional mutant ATXN1 mouse

Jason S. Mitchell, H. Zoghbi, J. Ervasti, 2023, bioRxiv.

Structure and Function of the Dystrophin-Glycoprotein Complex

J. Ervasti, 2013 .

Creatine kinase B is necessary to limit myoblast fusion during myogenesis.

J. Ervasti, G. Pavlath, L. Apponi, 2015, American journal of physiology. Cell physiology.

Impaired muscle relaxation and mitochondrial fission associated with genetic ablation of cytoplasmic actin isoforms

J. Ervasti, David D. Thomas, E. Spangenburg, 2018, The FEBS journal.

Pax3-induced expansion enables the genetic correction of dystrophic satellite cells

M. Kyba, R. Perlingeiro, J. Ervasti, 2015, Skeletal Muscle.

Axonal Regeneration and Neuronal Function Are Preserved in Motor Neurons Lacking ß-Actin In Vivo

J. Ervasti, Thomas R. Cheever, James M. Ervasti, 2011, PloS one.

Enhanced laminin binding by alpha-dystroglycan after enzymatic deglycosylation.

J. Ervasti, Ariana C. Combs, 2005, The Biochemical journal.