D. Craik

发表

Functional group contributions to drug-receptor interactions.

P. Andrews, D. Craik, J. L. Martín, 1984, Journal of medicinal chemistry.

Accurate de novo design of hyperstable constrained peptides

David Baker, James M. Olson, Thomas Szyperski, 2016, Nature.

Fmoc-based synthesis of disulfide-rich cyclic peptides.

D. Craik, David A. Price, O. Cheneval, 2014, The Journal of organic chemistry.

Three-dimensional structure of RTD-1, a cyclic antimicrobial defensin from Rhesus macaque leukocytes.

D. Craik, M. Trabi, H. Schirra, 2001, Biochemistry.

Approaches to the stabilization of bioactive epitopes by grafting and peptide cyclization

D. Craik, C. Schroeder, T. Durek, 2016, Biopolymers.

The Future of Peptide‐based Drugs

D. Craik, David A. Price, S. Liras, 2013, Chemical biology & drug design.

STRESS-INDUCED MAGNETIZATION

D. Craik, R. Fairholme, 1971 .

Studies on the membrane interactions of the cyclotides kalata B1 and kalata B6 on model membrane systems by surface plasmon resonance.

D. Craik, M. Aguilar, H. Kamimori, 2005, Analytical biochemistry.

Bioactive cystine knot proteins.

Norelle L Daly, David J Craik, D. Craik, 2011, Current opinion in chemical biology.

A novel two-chain proteinase inhibitor generated by circularization of a multidomain precursor protein

David J. Craik, Marilyn A. Anderson, Martin J. Scanlon, 1999, Nature Structural Biology.

Erratum: Ribosomally synthesized and post-translationally modified peptide natural products: Overview and recommendations for a universal nomenclature (Natural Product Reports (2013) 30 (108-160) DOI:10.1039/C2NP20085F)

P. G. Arnison, M. Bibb, B. Shen, 2013 .

Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature.

P. G. Arnison, M. Bibb, B. Shen, 2013, Natural product reports.

Engineering pro-angiogenic peptides using stable, disulfide-rich cyclic scaffolds.

Julie H. Campbell, D. Craik, S. Henriques, 2011, Blood.

THE SOLUTION STRUCTURE OF AMYLOID BETA-PEPTIDE (1-40) IN A WATER-MICELLE ENVIRONMENT. IS THE MEMBRANE-SPANNING DOMAIN WHERE WE THINK IT IS? NMR, 10 STRUCTURES

D. Craik, D. Fairlie, M. Coles, 1998 .

Disulfide Folding Pathways of Cystine Knot Proteins

D. Craik, N. Daly, R. Clark, 2003, The Journal of Biological Chemistry.

Homology model of thyroxine binding globulin and elucidation of the thyroid hormone binding site.

D. Craik, J. A. Jarvis, S. Munro, 1992, Protein engineering.

A new "era" for cyclotide sequencing.

D. Craik, Q. Kaas, M. Colgrave, 2010, Biopolymers.

MiAMP1, a novel protein from Macadamia integrifolia adopts a Greek key beta-barrel fold unique amongst plant antimicrobial proteins.

D. Craik, J. Manners, A. M. McManus, 1999, Journal of molecular biology.

Twists, Knots, and Rings in Proteins

Clement Waine, Norelle L Daly, David J Craik, 2003, The Journal of Biological Chemistry.

Conotoxins: natural product drug leads.

Reena Halai, David J Craik, D. Craik, 2009, Natural product reports.

Solution structure of methionine-oxidized amyloid beta-peptide (1-40). Does oxidation affect conformational switching?

D. Craik, D. Fairlie, A. A. Watson, 1998, Biochemistry.

Discovery, structure and biological activities of the cyclotides.

Jason Mulvenna, Norelle L Daly, David J Craik, 2004, Current protein & peptide science.

Albumins and their processing machinery are hijacked for cyclic peptides in sunflower.

D. Craik, N. Daly, M. Colgrave, 2011, Nature chemical biology.

Erratum to: “Cyclotide biosynthesis” [Curr Opin Chem Biol 2013, 17/4:546–554]

D. Craik, U. Malik, 2013 .

Mining the genome of Arabidopsis thaliana as a basis for the identification of novel bioactive peptides involved in oxidative stress tolerance.

Janick Mathys, D. Craik, L. Willem, 2013, Journal of experimental botany.

The C-terminal propeptide of a plant defensin confers cytoprotective and subcellular targeting functions

Marilyn A. Anderson, D. Craik, N. Daly, 2014, BMC Plant Biology.

Cyclotide biosynthesis.

D. Craik, U. Malik, 2013, Current opinion in chemical biology.

Thermal, chemical, and enzymatic stability of the cyclotide kalata B1: the importance of the cyclic cystine knot.

Michelle L Colgrave, David J Craik, D. Craik, 2004, Biochemistry.

Seamless Proteins Tie Up Their Loose Ends

David J. Craik, D. Craik, 2006, Science.

Comparison of a Short Linear Antimicrobial Peptide with Its Disulfide-Cyclized and Cyclotide-Grafted Variants against Clinically Relevant Pathogens

D. Craik, K. Hilpert, J. Gani, 2021, Microorganisms.

Purification and Structural Characterization of a Filamentous, Mucin-like Proteophosphoglycan Secreted by Leishmania Parasites*

D. Craik, Y. Stierhof, T. Ilg, 1996, The Journal of Biological Chemistry.

Lysine to arginine mutagenesis of chlorotoxin enhances its cellular uptake

D. Craik, S. Henriques, Conan K. Wang, 2017, Biopolymers.

Harnessing cyclotides to design and develop novel peptide GPCR ligands

D. Craik, C. Gruber, J. Koehbach, 2020, RSC chemical biology.

Cyclic peptide scaffold with ability to stabilize and deliver a helical cell-impermeable cargo across membranes of cultured cancer cells

D. Craik, P. Harvey, O. Cheneval, 2020, RSC Chemical Biology.

The cyclic cystine knot miniprotein MCoTI-II is internalized into cells by macropinocytosis.

D. Craik, J. Stow, N. Daly, 2007, The international journal of biochemistry & cell biology.

A common structural motif incorporating a cystine knot and a triple‐stranded β‐sheet in toxic and inhibitory polypeptides

D. Craik, R. Norton, P. K. Pallaghy, 1994, Protein science : a publication of the Protein Society.

Isolation and Characterization of Antimicrobial Peptides with Unusual Disulfide Connectivity from the Colonial Ascidian Synoicum turgens

D. Craik, K. Ø. Hansen, J. Isaksson, 2020, Marine drugs.

Identification, Characterization, and Three-Dimensional Structure of the Novel Circular Bacteriocin, Enterocin NKR-5-3B, from Enterococcus faecium.

D. Craik, K. Rosengren, J. Nakayama, 2015, Biochemistry.

NMR of peptide toxins

D. Craik, K. Rosengren, N. Daly, 2009 .

The solution structure of C1-T1, a two-domain proteinase inhibitor derived from a circular precursor protein from Nicotiana alata.

D. Craik, M. Anderson, H. Schirra, 2001, Journal of molecular biology.

Disulfide-rich macrocyclic peptides as templates in drug design.

D. Craik, C. Schroeder, T. Durek, 2014, European journal of medicinal chemistry.

Salt-Tolerant Antifungal and Antibacterial Activities of the Corn Defensin ZmD32

Marilyn A. Anderson, D. Craik, Thomas M A Shafee, 2019, Front. Microbiol..

Three-dimensional structure of RK-1: a novel alpha-defensin peptide.

D. Craik, D. Winzor, J. Wade, 2000, Biochemistry.

Structure of a putative ancestral protein encoded by a single sequence repeat from a multidomain proteinase inhibitor gene from Nicotiana alata.

D. Craik, M. Anderson, M. Scanlon, 1999, Structure.

Solution structure and proposed binding mechanism of a novel potassium channel toxin κ-conotoxin PVIIA

David J. Craik, Martin J. Scanlon, David Naranjo, 1997 .

NMR conformational studies of fenamate non‐steroidal anti‐inflammatory drugs

D. Craik, S. Munro, 1994 .

13C NMR studies of the molecular flexibility of antidepressants.

P. Andrews, D. Craik, D. J. Gale, 1986, Journal of pharmaceutical sciences.

Molecular engineering of conotoxins: the importance of loop size to alpha-conotoxin structure and function.

D. Craik, David John Adams, R. Lewis, 2008, Journal of medicinal chemistry.

The 1.1 A crystal structure of the neuronal acetylcholine receptor antagonist, alpha-conotoxin PnIA from Conus pennaceus.

D. Craik, L. Guddat, J. Martin, 1996, Structure.

Crystal structure at 1.1 A resolution of alpha-conotoxin PnIB: comparison with alpha-conotoxins PnIA and GI.

D. Craik, J. Martin, P. Alewood, 1997, Biochemistry.

Are α9α10 Nicotinic Acetylcholine Receptors a Pain Target for α-Conotoxins?

D. Craik, David John Adams, R. Clark, 2007, Molecular Pharmacology.

Solution structure of alpha-conotoxin ImI by 1H nuclear magnetic resonance.

D. Craik, N. Daly, P. Alewood, 1999, Journal of medicinal chemistry.

Delineation of the unbinding pathway of α-conotoxin ImI from the α7 nicotinic acetylcholine receptor.

Quentin Kaas, David J Craik, D. Craik, 2012, The journal of physical chemistry. B.

NMR of plant proteins.

D. Craik, Q. Kaas, 2013, Progress in nuclear magnetic resonance spectroscopy.

Mirror Images of Antimicrobial Peptides Provide Reflections on Their Functions and Amyloidogenic Properties.

D. Craik, A. Conibear, Stephanie Chaousis, 2016, Journal of the American Chemical Society.

Racemic and quasi-racemic X-ray structures of cyclic disulfide-rich peptide drug scaffolds.

D. Craik, Conan K. Wang, Paola G Ojeda, 2014, Angewandte Chemie.

Inhibitors of beta-amyloid formation based on the beta-secretase cleavage site.

R. Tanzi, D. Craik, D. Fairlie, 2000, Biochemical and biophysical research communications.

Thermally Activated Domain Wall Movement in Nickel-Iron Films

D. Craik, M. J. Wood, 1968, July 1.

Role of phosphorylation in the conformation of tau peptides implicated in Alzheimer's disease.

D. Craik, R. Hoffmann, L. Otvos, 2000, Biochemistry.

Structure and folding of disulfide‐rich miniproteins: Insights from molecular dynamics simulations and MM‐PBSA free energy calculations

D. Craik, L. Chiche, A. Heitz, 2008, Proteins.

Master Author Index

D. Craik, M. Trabi, F. Bedoya, 2004, FEBS Letters.

Comparative magnetostatic analyses of axisymmetric systems

D. Craik, A. Harrison, 1974 .

The Plant Decapeptide OSIP108 Can Alleviate Mitochondrial Dysfunction Induced by Cisplatin in Human Cells

S. Wölfl, D. Craik, O. Cheneval, 2014, Molecules.

NMRDyn: A Program for NMR Relaxation Studies of Protein Association

D. Craik, H. Schirra, Conan K. Wang, 2008, PloS one.

13C and 2H NMR studies of the molecular flexibility of phenylethylamine and amphetamine derivatives

D. Craik, B. Shehan, C. Border, 1993 .

13C NMR spin relaxation studies of molecular dynamics of substituted phenylbicyclo[2.2.2]octanes

G. C. Levy, D. Craik, W. Adcock, 1986 .

A critical evaluation of models for complex molecular dynamics: Application to NMR studies of double‐ and single‐stranded DNA

G. C. Levy, D. Craik, A. Kumar, 1983, Biopolymers.

Low-molecular-weight peptidic and cyclic antagonists of the receptor for the complement factor C5a.

D. Craik, D. Fairlie, Stephen M. Taylor, 1999, Journal of medicinal chemistry.

Enzymatic C-Terminal Protein Engineering with Amines.

D. Craik, T. Durek, S. D. de Veer, 2021, Journal of the American Chemical Society.

Synthesis, structure elucidation, in vitro biological activity, toxicity, and Caco-2 cell permeability of lipophilic analogues of alpha-conotoxin MII.

D. Craik, David John Adams, R. Lewis, 2003, Journal of medicinal chemistry.

Cyclotides: disulfide-rich peptide toxins in plants.

D. Craik, Yen‐Hua Huang, Qingdan Du, 2019, Toxicon : official journal of the International Society on Toxinology.

The three-dimensional solution structure by 1H NMR of a 6-kDa proteinase inhibitor isolated from the stigma of Nicotiana alata.

D. Craik, M. Anderson, R. Heath, 1994, Journal of molecular biology.

Conformational analysis of flexible antidepressant drugs

P. Andrews, D. Craik, S. Munro, 1987 .

A Pharmacophore Hypothesis for Antidepressant Activity

P. Andrews, D. Craik, S. Munro, 1987 .

C-13 NMR spectral studies of the thyroid hormone transport protein, transthyretin and the pancreatic insulin storage moiety, the zinc-insulin hexamer.

D. Craik, J. Hall, K. A. Higgins, 1987, Biochemical and biophysical research communications.

Importance of the cell membrane on the mechanism of action of cyclotides.

D. Craik, S. Henriques, 2012, ACS chemical biology.

Decoding the Membrane Activity of the Cyclotide Kalata B1

D. Craik, Yen‐Hua Huang, K. Rosengren, 2011, The Journal of Biological Chemistry.

Prediction of ortho(β) 13C chemical shifts in conjugated systems

D. Craik, B. Ternai, 1981 .

A consensus structure for omega-conotoxins with different selectivities for voltage-sensitive calcium channel subtypes: comparison of MVIIA, SVIB and SNX-202.

D. Craik, R. Lewis, P. Alewood, 1996, Journal of molecular biology.

Conformational studies by NMR of the antimicrobial peptide, drosocin, and its non-glycosylated derivative: effects of glycosylation on solution conformation.

D. Craik, R. Hoffmann, L. Otvos, 1999, Biochemistry.

NMR-Based Screening and Drug Discovery

D. Craik, R. Clark, Philippa A. Smith, 2010 .

Disulfide bond mutagenesis and the structure and function of the head-to-tail macrocyclic trypsin inhibitor SFTI-1.

D. Craik, R. Clark, M. Korsinczky, 2005, Biochemistry.

STRUCTURE AND FUNCTION OF PLANT TOXINS (WITH EMPHASIS ON CYSTINE KNOT TOXINS)

D. Craik, M. Plan, N. Daly, 2002 .

Design and characterization of novel antimicrobial peptides, R-BP100 and RW-BP100, with activity against Gram-negative and Gram-positive bacteria.

D. Craik, Yen‐Hua Huang, Inês M Torcato, 2013, Biochimica et biophysica acta.

The Cyclotide Fingerprint in Oldenlandia affinis: Elucidation of Chemically Modified, Linear and Novel Macrocyclic Peptides

D. Craik, M. Plan, N. Daly, 2007, Chembiochem : a European journal of chemical biology.

Variable‐temperature and pH studies of a DNA minor groove binder, Hoechst 32985, by 1H NMR spectroscopy

D. Craik, K. Cross, M. Coles, 1994 .

Holocyclotoxin-1, a cystine knot toxin from Ixodes holocyclus.

D. Craik, N. Daly, P. Alewood, 2014, Toxicon : official journal of the International Society on Toxinology.

RELATIONSHIP BETWEEN ATP RESYNTHESIS AND CALCIUM ACCUMULATION IN THE REPERFUSED RAT HEART

W. Nayler, D. Craik, Y. Hasin, 1992, Clinical and experimental pharmacology & physiology.

Altered Metabolism of Growth Hormone Receptor Mutant Mice: A Combined NMR Metabonomics and Microarray Study

D. Craik, M. Waters, H. Schirra, 2008, PloS one.

A comparative study of extraction methods reveals preferred solvents for cystine knot peptide isolation from Momordica cochinchinensis seeds.

D. Craik, J. Mylne, Aaron G. Poth, 2014, Fitoterapia.

Structural analysis of the N-linked glycan chains from a stylar glycoprotein associated with expression of self-incompatibility in Nicotiana alata.

J. R. Woodward, A. Bacic, D. Craik, 1992, Glycobiology.

Structure and distribution of N-glycans on the S7-allele stylar self-incompatibility ribonuclease of Nicotiana alata.

A. Bacic, D. Craik, D. Oxley, 1998, Journal of Biochemistry (Tokyo).

Structural analysis and molecular model of a self-incompatibility RNase from wild tomato.

A. Bacic, D. Craik, E. Newbigin, 1998, Plant physiology.

Cell Wall Polysaccharides from Australian Red Algae of the Family Solieriaceae (Gigartinales, Rhodophyta): Highly Methylated Carrageenans from the Genus Rhabdonia

A. Bacic, D. Craik, A. Chiovitti, 1996 .

Cell-wall polysaccharides from Australian red algae of the family Solieriaceae (Gigartinales, Rhodophyta): novel, highly pyruvated carrageenans from the genus Callophycus

A. Bacic, D. Craik, A. Chiovitti, 1997 .

The Chemistry and Biology of Human Relaxin‐3

D. Craik, J. Wade, A. Gundlach, 2005, Annals of the New York Academy of Sciences.

D. Craik, Hanmei Xu, Mengwei Li, 2022, Cancer letters.

Antinociceptive peptides from venomous arthropods

D. Craik, L. Y. Chan, J. Koehbach, 2022, Toxin Reviews.

Cyclic analogues of α‐conotoxin Vc1.1 inhibit colonic nociceptors and provide analgesia in a mouse model of chronic abdominal pain

D. Craik, David John Adams, Q. Kaas, 2018, British journal of pharmacology.

Identification of two suites of cyclotide precursor genes from metallophyte Viola baoshanensis: cDNA sequence variation, alternative RNA splicing and potential cyclotide diversity.

D. Craik, W. Shu, B. Liao, 2009, Gene.

Synthesis and structure determination by NMR of a putative vacuolar targeting peptide and model of a proteinase inhibitor from Nicotiana alata.

D. Craik, M. Anderson, K. Nielsen, 1996, Biochemistry.

Distribution of circular proteins in plants: large-scale mapping of cyclotides in the Violaceae

D. Craik, K. Rosengren, U. Göransson, 2015, Front. Plant Sci..

Biochemical and biophysical characterization of a novel plant protein disulfide isomerase

D. Craik, C. Gruber, A. Mechler, 2009, Biopolymers.

A Novel Plant Protein-disulfide Isomerase Involved in the Oxidative Folding of Cystine Knot Defense Proteins*

Marilyn A. Anderson, D. Craik, T. Horibe, 2007, Journal of Biological Chemistry.

Understanding the Diversity and Distribution of Cyclotides from Plants of Varied Genetic Origin.

D. Craik, Yen‐Hua Huang, M. Colgrave, 2017, Journal of natural products.

Stage-specific Proteophosphoglycan from Leishmania mexicana Amastigotes

A. Bacic, D. Craik, G. Multhaup, 1998, The Journal of Biological Chemistry.

The Yariv reagent: behaviour in different solvents and interaction with a gum arabic arabinogalactan-protein.

A. Bacic, D. Craik, B. Paulsen, 2014, Carbohydrate polymers.

Pyruvated carrageenans from Solieria robusta and its adelphoparasite Tikvahiella candida

A. Bacic, D. Craik, A. Chiovitti, 1999, Hydrobiologia.

A nearly idealized 6'-O-methylated iota-carrageenan from the Australian red alga Claviclonium ovatum (Acrotylaceae, Gigartinales).

A. Bacic, D. Craik, A. Chiovitti, 2004, Carbohydrate research.

CHEMISTRY, PROPERTIES, AND PHYLOGENETIC IMPLICATIONS OF THE METHYLATED CARRAGEENANS FROM RED ALGAE OF THE GENUS ARESCHOUGIA (ARESCHOUGIACEAE, GIGARTINALES, RHODOPHYTA)

A. Bacic, D. Craik, A. Chiovitti, 2001 .

CARRAGEENANS FROM AUSTRALIAN REPRESENTATIVES OF THE FAMILY CYSTOCLONIACEAE (GIGARTINALES, RHODOPHYTA), WITH DESCRIPTION OF CALLIBLEPHARIS CELATOSPORA SP. NOV., AND TRANSFER OF AUSTROCLONIUM TO THE FAMILY ARESCHOUGIACEAE

A. Bacic, D. Craik, A. Chiovitti, 1998 .

Carrageenans with complex substitution patterns from red algae of the genus Erythroclonium

A. Bacic, D. Craik, A. Chiovitti, 1997 .

Sulfated galactans from Australian specimens of the red alga Phacelocarpus peperocarpos (Gigartinales, Rhodophyta).

A. Bacic, D. Craik, A. Chiovitti, 1996, Carbohydrate research.

Structure of N-glycans on the S3- and S6- stylar self-incompatibility ribonucleases of Nicotiana alata

A. Bacic, D. Craik, D. Oxley, 1996 .

Structural analysis of the carbohydrate moiety of arabinogalactan-proteins from stigmas and styles of Nicotiana alata.

A. Bacic, D. Craik, G. Howlett, 1995, Carbohydrate research.

Structure of the N-linked oligosaccharides from tridacnin, a lectin found in the haemolymph of the giant clam Hippopus hippopus.

A. Bacic, D. Craik, N. Puanglarp, 1995, European journal of biochemistry.

Quantitative analysis of backbone-cyclised peptides in plants.

Marilyn A. Anderson, D. Craik, M. Colgrave, 2008, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Proteome analysis of the hyaluronic acid-producing bacterium, Streptococcus zooepidemicus

L. Nielsen, D. Craik, E. Marcellin, 2009, Proteome Science.

High level of aspartic acid‐bond isomerization during the synthesis of an N‐linked τ glycopeptide

D. Craik, R. Hoffmann, L. Otvos Jr, 1999, Journal of peptide science : an official publication of the European Peptide Society.

Evaluation of Cyclic Peptide Inhibitors of the Grb7 Breast Cancer Target: Small Change in Cargo Results in Large Change in Cellular Activity

D. Craik, J. Wilce, Jianrong Sang, 2019, Molecules.

The Antimicrobial Activity of Sub3 is Dependent on Membrane Binding and Cell‐Penetrating Ability

D. Craik, Yen‐Hua Huang, S. Henriques, 2013, Chembiochem : a European journal of chemical biology.

Structural Analysis and Molecular Model of a Self-Incompatibility RNase from Wild Tomato 1

A. Bacic, D. Craik, E. Newbigin, 1998 .

Therapeutic conotoxins: a US patent literature survey

D. Craik, T. Durek, 2015, Expert opinion on therapeutic patents.

Conotoxins and Other Conopeptides

D. Craik, Q. Kaas, 2014 .

Conopeptide characterization and classifications: an analysis using ConoServer.

D. Craik, Q. Kaas, Jan-Christoph Westermann, 2010, Toxicon : official journal of the International Society on Toxinology.

Neurotoxic and cytotoxic peptides underlie the painful stings of the tree nettle Urtica ferox

D. Craik, I. Vetter, P. Harvey, 2022, The Journal of biological chemistry.

Defense Peptides Engineered from Human Platelet Factor 4 Kill Plasmodium by Selective Membrane Disruption.

D. Craik, Adele M. Lehane, P. Harvey, 2018, Cell chemical biology.

Synthetic Glycopeptide Models of MUC1 Core Protein

D. Craik, L. Otvos, M. Cudic, 2001 .

Peptide quantification by matrix-assisted laser desorption ionisation time-of-flight mass spectrometry: investigations of the cyclotide kalata B1 in biological fluids.

D. Craik, M. Colgrave, Alun Jones, 2005, Journal of chromatography. A.

NMR Studies of Ligand–Macromolecule Interactions

D. Craik, K. A. Higgins, 1990 .

Design and synthesis of truncated EGF-A peptides that restore LDL-R recycling in the presence of PCSK9 in vitro.

M. Ammirati, D. Craik, David A. Price, 2014, Chemistry & biology.

Evolving biotechnology - an adaptive conceptual model of the biotechnology firm

D. Craik, D. Hine, D. Ireland, 2005 .

Anti-HIV cyclotides from the Chinese medicinal herb Viola yedoensis.

K. Gustafson, D. Craik, Conan K. Wang, 2008, Journal of natural products.

NMR relaxation behavior and quadrupole coupling constants of 39K and 23Na ions in glycerol. Comparisons with 39K tissue data

D. Craik, B. Shehan, R. Wellard, 1992 .

θ-Defensins Prevent HIV-1 Env-mediated Fusion by Binding gp41 and Blocking 6-Helix Bundle Formation*

S. A. Gallo, D. Craik, A. Waring, 2006, Journal of Biological Chemistry.

Design of a cyclotide antagonist of neuropilin-1 and -2 that potently inhibits endothelial cell migration.

Jennifer A. Getz, D. Craik, O. Cheneval, 2013, ACS chemical biology.

Crown-of-thorns starfish in captivity experience sustained large-scale changes in gene expression

B. Degnan, D. Craik, S. Degnan, 2022, bioRxiv.

Domain Theory and Observation

D. Craik, 1967 .

Towards a generic prototyping approach for therapeutically-relevant peptides and proteins in a cell-free translation system

Yuehua Wu, D. Craik, I. Vetter, 2022, Nature communications.

Papain-like cysteine proteases prepare plant cyclic peptide precursors for cyclization

D. Craik, T. Durek, M. Jackson, 2019, Proceedings of the National Academy of Sciences of the United States of America.

Nomenclature of homodetic cyclic peptides produced from ribosomal precursors: An IUPAC task group interim report

G. P. Moss, D. Craik, U. Göransson, 2016, Biopolymers.

Recent progress towards pharmaceutical applications of disulfide-rich cyclic peptides.

D. Craik, C. Schroeder, Joakim E. Swedberg, 2013, Current protein & peptide science.

Discovery of an unusual biosynthetic origin for circular proteins in legumes

R. Lyons, D. Craik, N. Daly, 2011, Proceedings of the National Academy of Sciences.

How bugs make lassos.

D. Craik, K. Rosengren, K. J. Rosengren, 2009, Chemistry & biology.

Circular proteins from Melicytus (Violaceae) refine the conserved protein and gene architecture of cyclotides.

D. Craik, M. Trabi, J. Mylne, 2009, Organic & biomolecular chemistry.

The Anthelmintic Activity of the Cyclotides: Natural Variants with Enhanced Activity

D. Craik, Conan K. Wang, M. Colgrave, 2008, Chembiochem : a European journal of chemical biology.

Backbone cyclised peptides from plants show molluscicidal activity against the rice pest Pomacea canaliculata (golden apple snail).

D. Craik, M. Plan, A. Cagauan, 2008, Journal of agricultural and food chemistry.

Cyclotides: natural, circular plant peptides that possess significant activity against gastrointestinal nematode parasites of sheep.

D. Craik, Yen‐Hua Huang, M. Colgrave, 2008, Biochemistry.

Plant cyclotides disrupt epithelial cells in the midgut of lepidopteran larvae

Marilyn A. Anderson, D. Craik, A. Marshall, 2008, Proceedings of the National Academy of Sciences.

Biosynthesis of circular proteins in plants.

Marilyn A. Anderson, Cameron V. Jennings, D. Craik, 2007, The Plant journal : for cell and molecular biology.

An Asparaginyl Endopeptidase Mediates in Vivo Protein Backbone Cyclization*

Marilyn A. Anderson, D. Craik, R. Dietzgen, 2007, Journal of Biological Chemistry.

Chemical synthesis and biosynthesis of the cyclotide family of circular proteins

Marilyn A. Anderson, D. Craik, N. Daly, 2006, IUBMB life.

Cycloviolacin H4, a hydrophobic cyclotide from Viola hederaceae.

D. Craik, Conan K. Wang, M. Colgrave, 2006, Journal of natural products.

Protease-catalysed protein splicing: a new post-translational modification?

D. Craik, I. Saska, 2008, Trends in biochemical sciences.

Cyclization of conotoxins to improve their biopharmaceutical properties.

D. Craik, Q. Kaas, N. Daly, 2012, Toxicon : official journal of the International Society on Toxinology.

Establishing regiocontrol of disulfide bond isomers of α‐conotoxin ImI via the synthesis of N‐to‐C cyclic analogs

D. Craik, P. Alewood, J. Dutton, 2009, Biopolymers.

Criteria for uniaxial magnetostatic behaviour in thin platelets

D. Craik, P. Cooper, 1972 .

Cyclotide proteins and precursors from the genus Gloeospermum: filling a blank spot in the cyclotide map of Violaceae.

Mahabir P. Gupta, D. Craik, Mahabir P Gupta, 2010, Phytochemistry.

The alpine violet, Viola biflora, is a rich source of cyclotides with potent cytotoxicity.

D. Craik, U. Göransson, R. Clark, 2008, Phytochemistry.

Hormone-like conopeptides - new tools for pharmaceutical design.

D. Craik, Q. Kaas, Ashlin Turner, 2020, RSC medicinal chemistry.

Effects of backbone cyclization on the pharmacokinetics and drug ef ﬁ ciency of the orally active analgesic conotoxin cVc1.1 in Drug

D. Craik, T. Durek, D. Venter, 2021 .

Transforming conotoxins into cyclotides: Backbone cyclization of P‐superfamily conotoxins

D. Craik, N. Daly, R. Clark, 2015, Biopolymers.

A novel (cid:1) 4/7-conotoxin LvIA from Conus lividus that selectively blocks (cid:1) 3 (cid:2) 2 vs . (cid:1) 6/ (cid:1) 3 (cid:2) 2 (cid:2) 3 nicotinic acetylcholine receptors

D. Craik, Q. Kaas, C. Schroeder, 2014 .

Scanning Mutagenesis of α-Conotoxin Vc1.1 Reveals Residues Crucial for Activity at the α9α10 Nicotinic Acetylcholine Receptor*

D. Craik, David John Adams, Reena Halai, 2009, The Journal of Biological Chemistry.

Conotoxin modulation of voltage-gated sodium channels.

D. Craik, David John Adams, J. Ekberg, 2008, The international journal of biochemistry & cell biology.

Factors Influencing the Stability of Cyclotides: Proteins with a Circular Backbone and Cystine Knot Motif

D. Craik, M. Cemazar, 2006, International Journal of Peptide Research and Therapeutics.

Backbone cyclization improves the enzymatic stability of chi-conotoxin, MrIA, whilst maintaining its structure and NET-modulating activity

D. Craik, N. Daly, M. Colgrave, 2006 .

Two new classes of conopeptides inhibit the α1-adrenoceptor and noradrenaline transporter

D. Craik, David John Adams, R. Lewis, 2001, Nature Neuroscience.

Interaction of Synthetic Human SLURP-1 with the Nicotinic Acetylcholine Receptors

D. Craik, P. Corringer, David John Adams, 2017, Scientific Reports.

The Chemistry of Cyclotides

D. Craik, A. C. Conibear, 2011 .

Interlocking disulfides in circular proteins: toward efficient oxidative folding of cyclotides.

D. Craik, U. Göransson, R. Clark, 2011, Antioxidants & redox signaling.

Solution structure and proposed binding mechanism of a novel potassium channel toxin kappa-conotoxin PVIIA.

D. Craik, R. Lewis, M. Scanlon, 1997, Structure.

Discovery of Cyclotides from Australasian Plants

D. Craik, M. Kan, 2020 .

Characterization of Synthetic Tf2 as a NaV1.3 Selective Pharmacological Probe

D. Craik, I. Vetter, T. Durek, 2020, Biomedicines.

The chemistry and biology of cyclotides.

D. Craik, N. Daly, M. Cemazar, 2007, Current opinion in drug discovery & development.

Alpha-selenoconotoxins, a new class of potent alpha7 neuronal nicotinic receptor antagonists.

D. Craik, David John Adams, N. Daly, 2006, The Journal of biological chemistry.

Solution structures of the cis- and trans-Pro30 isomers of a novel 38-residue toxin from the venom of Hadronyche Infensa sp. that contains a cystine-knot motif within its four disulfide bonds.

D. Craik, K. Rosengren, N. Daly, 2002, Biochemistry.

Three-dimensional solution structure of mu-conotoxin GIIIB, a specific blocker of skeletal muscle sodium channels.

D. Craik, P. Alewood, J. Hill, 1996, Biochemistry.

Peptides from mamba venom as pain killers.

D. Craik, C. Schroeder, 2013, Angewandte Chemie.

An N-capping asparagine–lysine–proline (NKP) motif contributes to a hybrid flexible/stable multifunctional peptide scaffold

Karen G. N. Oshiro, T. Lu, D. Craik, 2022, Chemical science.

Insecticidal spider toxins are high affinity positive allosteric modulators of the nicotinic acetylcholine receptor

D. Craik, Davide Sabbadin, Q. Kaas, 2019, FEBS letters.

The cystine knot motif in toxins and implications for drug design.

D. Craik, N. Daly, C. Waine, 2001, Toxicon : official journal of the International Society on Toxinology.

Lysine-rich Cyclotides: A New Subclass of Circular Knotted Proteins from Violaceae.

D. Craik, Q. Kaas, S. Henriques, 2015, ACS chemical biology.

Gly(6) of kalata B1 is critical for the selective binding to phosphatidylethanolamine membranes.

D. Craik, M. Aguilar, K. Hall, 2012, Biochimica et biophysica acta.

Effects of Lys2 to Ala2 substitutions on the structure and potency of ω-conotoxins MVIIA and CVID.

D. Craik, C. Schroeder, R. Lewis, 2012, Biopolymers.

Cyclotides: a patent review

D. Craik, N. Daly, Amanda Smith, 2011, Expert opinion on therapeutic patents.

Discovery and applications of the plant cyclotides.

D. Craik, 2010, Toxicon : official journal of the International Society on Toxinology.

Cyclotide Interactions with the Nematode External Surface

D. Craik, Yen‐Hua Huang, M. Colgrave, 2010, Antimicrobial Agents and Chemotherapy.

Sunflower trypsin inhibitor-1, proteolytic studies on a trypsin inhibitor peptide and its analogs.

D. Craik, M. Colgrave, R. Clark, 2010, Biopolymers.

Evaluation of toxicity and antitumor activity of cycloviolacin O2 in mice.

D. Craik, L. Bohlin, U. Göransson, 2010, Biopolymers.

Design and therapeutic applications of cyclotides.

D. Craik, N. Daly, 2009, Future medicinal chemistry.

Circling the enemy: cyclic proteins in plant defence.

D. Craik, 2009, Trends in plant science.

Anthelmintic activity of cyclotides: In vitro studies with canine and human hookworms.

J. McCarthy, D. Craik, M. Colgrave, 2009, Acta tropica.

Microwave‐assisted Boc‐solid phase peptide synthesis of cyclic cysteine‐rich peptides

D. Craik, M. Cemazar, 2008, Journal of peptide science : an official publication of the European Peptide Society.

Alanine Scanning Mutagenesis of the Prototypic Cyclotide Reveals a Cluster of Residues Essential for Bioactivity*

D. Craik, K. Rosengren, Conan K. Wang, 2008, Journal of Biological Chemistry.

15N cyclotides by whole plant labeling

D. Craik, J. Mylne, 2008, Biopolymers.

Discovery and structures of the cyclotides: novel macrocyclic peptides from plants

Marilyn A. Anderson, D. Craik, J. Mulvenna, 2001, Letters in Peptide Science.

Diversity in the disulfide folding pathways of cystine knot peptides

D. Craik, N. Daly, U. Göransson, 2006, Letters in Peptide Science.

Plant cyclotides: circular, knotted peptide toxins.

D. Craik, 2001, Toxicon : official journal of the International Society on Toxinology.

Structure-activity studies of conantokins as human N-methyl-D-aspartate receptor modulators.

D. Craik, R. Lewis, P. Dodd, 1999, Journal of medicinal chemistry.

The atypical α -conotoxin LtIA from C onus litteratus targets a novel microsite of the alpha3beta2 nicotinic receptor*

D. Craik, R. Lewis, N. Daly, 2010 .

Binding mode of alpha-conotoxins to an acetylcholine binding protein determined by saturation transfer difference NMR.

D. Craik, R. Clark, Jan-Christoph Westermann, 2008, Protein and peptide letters.

NMR of Conotoxins: Structural Features and Analysis of Chemical Shifts of Posttranslationally Modified Amino Acids

D. Craik, U. Marx, N. Daly, 2006 .

Cyclic alpha-conotoxin peptidomimetic chimeras as potent GLP-1R agonists.

D. Craik, P. Loria, David A. Price, 2015, European journal of medicinal chemistry.

VACUOLAR TARGETING PEPTIDE FROM NA-PROPI

Marilyn A. Anderson, D. Craik, K. Nielsen, 1996 .

Safer In Vitro Drug Screening Models for Melioidosis Therapy Development.

D. Craik, S. Henriques, B. Currie, 2020, The American journal of tropical medicine and hygiene.

Drug susceptibility profiling of Australian Burkholderia species as models for developing melioidosis therapeutics

D. Craik, S. Henriques, B. Currie, 2020, bioRxiv.

Substituent Effects on Chemical Shifts in the Sidechains of Aromatic Systems

D. Craik, R. Brownlee, 2007 .

The relationship between 19F substituent chemical shifts and electron densities: meta- and para-substituted benzoyl fluorides

D. Craik, R. Brownlee, 1980 .

Nonadditive carbon-13 nuclear magnetic resonance substituent shifts in 1,4-disubstituted benzenes. Nonlinear resonance and shift-charge ratio effects

R. Taft, D. Craik, M. Sadek, 1980 .

Cell wall polysaccharides from Australian red algae of the family Solieriaceae (Gigartinales, Rhodophyta): iota/kappa/beta-carrageenans from Melanema dumosum

A. Bacic, D. Craik, A. Chiovitti, 1995 .

Chemical synthesis, antibacterial activity and conformation of diptericin, an 82-mer peptide originally isolated from insects.

D. Craik, R. Hoffmann, L. Otvos, 1999, European journal of biochemistry.

Understanding the structure/activity relationships of the iron regulatory peptide hepcidin.

D. Craik, T. Ganz, E. Nemeth, 2011, Chemistry & biology.

Photodegradation of irinotecan (CPT-11) in aqueous solutions: identification of fluorescent products and influence of solution composition.

D. Craik, H. Dodds, L. Rivory, 1997, Journal of pharmaceutical sciences.

Molecular dynamics simulations of dihydro‐β‐erythroidine bound to the human α4β2 nicotinic acetylcholine receptor

D. Craik, David John Adams, Q. Kaas, 2019, British journal of pharmacology.

Design, synthesis, and characterization of a single-chain peptide antagonist for the relaxin-3 receptor RXFP3.

D. Craik, J. Wade, K. Rosengren, 2011, Journal of the American Chemical Society.

Small molecular probes for G-protein-coupled C5a receptors: conformationally constrained antagonists derived from the C terminus of the human plasma protein C5a.

D. Craik, D. Fairlie, G. Pierens, 1998, Journal of medicinal chemistry.

Characterization of a Novel α-Conotoxin from Conus textile That Selectively Targets α6/α3β2β3 Nicotinic Acetylcholine Receptors*

D. Craik, J. McIntosh, Sean B. Christensen, 2012, The Journal of Biological Chemistry.

alpha-Conotoxins: nicotinic acetylcholine receptor antagonists as pharmacological tools and potential drug leads.

D. Craik, J. Dutton, 2001, Current medicinal chemistry.

µ-Conotoxins Targeting the Human Voltage-Gated Sodium Channel Subtype NaV1.7

D. Craik, I. Vetter, C. Schroeder, 2022, Toxins.

A novel conotoxin inhibitor of Kv1.6 channel and nAChR subtypes defines a new superfamily of conotoxins.

D. Craik, N. Daly, B. Olivera, 2006, Biochemistry.

The synthesis and structure of an n-terminal dodecanoic acid conjugate of α-conotoxin MII

D. Craik, David John Adams, I. Toth, 2001, Letters in Peptide Science.

Development of a μO-conotoxin analogue with improved lipid membrane interactions and potency for the analgesic target Na V 1.8

D. Craik, I. Vetter, S. Henriques, 2016 .

Design of substrate-based BCR-ABL kinase inhibitors using the cyclotide scaffold

D. Craik, Q. Kaas, Yen‐Hua Huang, 2015, Scientific Reports.

Structure of human insulin-like peptide 5 and characterization of conserved hydrogen bonds and electrostatic interactions within the relaxin framework.

D. Craik, J. Wade, K. Rosengren, 2009, The Biochemical journal.

Design of a Stable Cyclic Peptide Analgesic Derived from Sunflower Seeds that Targets the κ-Opioid Receptor for the Treatment of Chronic Abdominal Pain

D. Craik, S. Brierley, C. Gruber, 2021, Journal of medicinal chemistry.

Co-expression of a cyclizing asparaginyl endopeptidase enables efficient production of cyclic peptides in planta

Marilyn A. Anderson, D. Craik, T. Durek, 2017, Journal of experimental botany.

A designed cyclic analogue of gomesin has potent activity against Staphylococcus aureus biofilms

D. Craik, O. Cheneval, A. Coutinho, 2022, The Journal of antimicrobial chemotherapy.

Anthelminthic activity of the cyclotides (kalata B1 and B2) against schistosome parasites.

D. Craik, D. McManus, Malcolm K. Jones, 2013, Biopolymers.

Effects of cyclotides against cutaneous infections caused by Staphylococcus aureus

D. Craik, O. Franco, O. N. Silva, 2015, Peptides.

Solution Structure and Novel Insights into the Determinants of the Receptor Specificity of Human Relaxin-3*

D. Craik, J. Wade, K. Rosengren, 2006, Journal of Biological Chemistry.

Antimicrobial Peptide Mimetics Based on a Diphenylacetylene Scaffold: Synthesis, Conformational Analysis, and Activity

D. Craik, A. Hamilton, Jinghui Luo, 2020, ChemMedChem.

Total synthesis of the analgesic conotoxin MrVIB through selenocysteine-assisted folding.

D. Craik, David John Adams, Gene Hopping, 2011, Angewandte Chemie.

Substrate-Guided Design of Selective FXIIa Inhibitors Based on the Plant-Derived Momordica cochinchinensis Trypsin Inhibitor-II (MCoTI-II) Scaffold.

D. Craik, C. Schroeder, Jonathan M. Harris, 2016, Journal of medicinal chemistry.

Cyclotides as templates for peptide GPCR ligand design - discovery of the target receptor of the oxytocic plant peptide kalata B7

Terry J. Smith, D. Craik, S. Wray, 2013 .

Membrane-active peptides escape drug-resistance in cancer

D. Craik, S. Blanksby, S. Henriques, 2022, bioRxiv.

Solution structure of the B-chain of insulin as determined by 1H NMR spectroscopy. Comparison with the crystal structure of the insulin hexamer and with the solution structure of the insulin monomer.

D. Craik, K. Cross, B. Hawkins, 1996, International journal of peptide and protein research.

Cyclotides: plant defense toxins

D. Craik, M. Kan, Georgianna K. Oguis, 2017 .

Cyclotide Structure and Function: The Role of Membrane Binding and Permeation.

D. Craik, S. Troeira Henriques, 2017, Biochemistry.

Phosphatidylethanolamine Binding Is a Conserved Feature of Cyclotide-Membrane Interactions*

D. Craik, Yen‐Hua Huang, L. Bagatolli, 2012, The Journal of Biological Chemistry.

13C NMR studies of insulin. Part I—Spectral assignments

P. Andrews, D. Craik, K. A. Higgins, 1989, Magnetic resonance in chemistry : MRC.

MOLDYN: a generalized program for the evaluation of molecular dynamics models using nuclear magnetic resonance spin-relaxation data

Anil Kumar, David J. Craik, George C. Levy, 1983, J. Chem. Inf. Comput. Sci..

Ring flexibility within tricyclic antidepressant drugs.

D. Craik, M. Casarotto, 2001, Journal of pharmaceutical sciences.

1H and 13C NMR relaxation studies of molecular dynamics of the thyroid hormones thyroxine, 3,5,3'-triiodothyronine, and 3,5-diiodothyronine.

D. Craik, B. Duggan, 1996, Journal of medicinal chemistry.

13C NMR studies of the solution molecular dynamics of tricyclic antidepressants

D. Craik, M. Casarotto, S. Munro, 1990 .

Late-Stage Functionalization with Cysteine Staples Generates Potent and Selective Melanocortin Receptor-1 Agonists.

Andrew M. White, A. Plowright, D. Craik, 2022, Journal of medicinal chemistry.

Structure of thermolysin cleaved microcin J25: extreme stability of a two-chain antimicrobial peptide devoid of covalent links.

D. Craik, K. Rosengren, J. Tabet, 2004, Biochemistry.

Structural characterisation of xyloglucan secreted by suspension-cultured cells of Nicotiana plumbaginifolia.

A. Bacic, D. Craik, I. Sims, 2020, Carbohydrate research.

Improving Stability Enhances In Vivo Efficacy of a PCSK9 Inhibitory Peptide.

D. Craik, Yen‐Hua Huang, Conan K. Wang, 2022, Journal of the American Chemical Society.

Quantification of small cyclic disulfide‐rich peptides

D. Craik, N. Daly, A. C. Conibear, 2012, Biopolymers.

Structure of the second copper binding domain of the Menkes ATPase

Christopher E. Jones, D. Craik, P. Cobine, 2001 .

Development of a (cid:2) O-Conotoxin Analogue with Improved Lipid Membrane Interactions and Potency for the Analgesic Sodium Channel Na V 1.8 *

D. Craik, I. Vetter, C. Schroeder, 2020 .

Identification of survival-promoting OSIP108 peptide variants and their internalization in human cells

D. Craik, P. Harvey, D. Cassiman, 2017, Mechanisms of Ageing and Development.

Mechanisms of bacterial membrane permeabilization by crotalicidin (Ctn) and its fragment Ctn(15–34), antimicrobial peptides from rattlesnake venom

Marco M. Domingues, D. Craik, G. Rádis-Baptista, 2017, The Journal of Biological Chemistry.

Potent, Selective, and Cell-Penetrating Inhibitors of Kallikrein-Related Peptidase 4 Based on the Cyclic Peptide MCoTI-II.

D. Craik, Jonathan M. Harris, S. D. de Veer, 2018, ACS medicinal chemistry letters.

Cellular Uptake and Cytosolic Delivery of a Cyclic Cystine Knot Scaffold.

Joshua A. Kritzer, D. Craik, Yen‐Hua Huang, 2020, ACS chemical biology.

Magnetic fields from subdivided surfaces

D. Craik, 1966 .

The Domain Structure of Ordered Platinum-Cobalt Alloy

D. Craik, F. Nunez, 1961 .

Is the mirror image a true reflection? Intrinsic membrane chirality modulates peptide binding.

D. Craik, S. Henriques, Conan K. Wang, 2019, Journal of the American Chemical Society.

Chemical and biological consequences of sugar incorporation into a potential N-glycosylation site in the tubulin-binding repeat of tau protein

D. Craik, J. Wade, L. Otvos, 2002 .

Accurate de novo design of membrane-traversing macrocycles

Timothy W. Craven, Stephen A. Rettie, M. J. Bick, 2022, Cell.

Cyclotide isolation and characterization.

D. Craik, S. Henriques, Conan K. Wang, 2012, Methods in enzymology.

Make it or break it: Plant AEPs on stage in biotechnology.

D. Craik, T. Durek, M. Jackson, 2020, Biotechnology advances.

The cyclic cystine ladder in theta-defensins is important for structure and stability, but not antibacterial activity*

D. Craik, K. Rosengren, S. Henriques, 2013 .

Cyclotides Insert into Lipid Bilayers to Form Membrane Pores and Destabilize the Membrane through Hydrophobic and Phosphoethanolamine-specific Interactions*

D. Craik, Conan K. Wang, H. Wacklin, 2012, The Journal of Biological Chemistry.

Conformational analysis of LYS(11-36), a peptide derived from the beta-sheet region of T4 lysozyme, in TFE and SDS.

D. Craik, J. Wade, M. McLeish, 1997, Biochemistry.

Structural Insights into the Function of Relaxins

D. Craik, J. Wade, K. Rosengren, 2009, Annals of the New York Academy of Sciences.

Structural Properties of Relaxin Chimeras

D. Craik, J. Wade, K. Rosengren, 2009, Annals of the New York Academy of Sciences.

Structure of the R3/I5 Chimeric Relaxin Peptide, a Selective GPCR135 and GPCR142 Agonist*

D. Craik, J. Wade, K. Rosengren, 2008, Journal of Biological Chemistry.

Two Blast-independent tools, CyPerl and CyExcel, for harvesting hundreds of novel cyclotides and analogues from plant genomes and protein databases

D. Craik, Zebo Huang, A. Baker, 2015, Planta.

Threaded rings and complex topologies in antimicrobial peptides: Nature's engineering templates

D. Craik, K. Rosengren, L. Sando, 2006 .

Effect of signal-to-noise ratio on the measurement of individual T1 values from superimposed peaks

D. Craik, B. Shehan, K. A. Higgins, 1991 .

Inhibition of tau aggregation using a naturally-occurring cyclic peptide scaffold.

D. Craik, Yen‐Hua Huang, Conan K. Wang, 2016, European journal of medicinal chemistry.

Overview on the discovery and applications of cyclotides

D. Craik, 2015 .

Self-Association of Nicotinamide in Aqueous-Solution - Nmr-Studies of Nicotinamide and the Mono-Methyl-Substituted and Di-Methyl-Substituted Amide Analogs

D. Craik, W. Charman, B. Finnin, 1993 .

Non‐additive carbon‐13 NMR substituent chemical shifts. II —1,3‐disubstituted benzenes

D. Craik, M. Sadek, R. Brownlee, 1986 .

Novel ω-Conotoxins from Conus catus Discriminate among Neuronal Calcium Channel Subtypes*

P. Andrews, D. Craik, David John Adams, 2000, The Journal of Biological Chemistry.

The derivation of “bubble” material parameters from magnetization curves

D. Craik, 1972 .

Sex-specific expression of pheromones and other signals in gravid starfish

B. Degnan, D. Craik, S. Degnan, 2022, BMC biology.

Butterfly Pea (Clitoria ternatea), a Cyclotide-Bearing Plant With Applications in Agriculture and Medicine

D. Craik, M. Jackson, E. Gilding, 2019, Front. Plant Sci..

Engineered Conotoxin Differentially Blocks and Discriminates Rat and Human α7 Nicotinic Acetylcholine Receptors.

D. Craik, P. Harvey, Q. Kaas, 2021, Journal of medicinal chemistry.

Novel α-CTx TxIB Selectively Blocks α 6 / α 3 β 2 β 3 nAChRs 1 Characterization of a Novel α-Conotoxin from Conus textile that Selectively Targets α 6 / α 3 β 2 β 3 Nicotinic Acetylcholine Receptors

D. Craik, J. McIntosh, Sean B. Christensen, 2012 .

Studies of protein-ligand interactions by NMR.

D. Craik, J. Wilce, 1997, Methods in molecular biology.

Phosphorylation of the C-terminal sites of human p53 reduces non-sequence-specific DNA binding as modeled with synthetic peptides.

D. Craik, R. Hoffmann, L. Otvos, 1998, Biochemistry.

Bioinformatics-Aided Venomics

David J. Craik, Quentin Kaas, D. Craik, 2015, Toxins.

Natural Functions and Structure–Activity Relationships of Cyclotides

D. Craik, M. Kan, Georgianna K. Oguis, 2015 .

Solution structure of amyloid beta-peptide(1-40) in a water-micelle environment. Is the membrane-spanning domain where we think it is?

D. Craik, D. Fairlie, M. Coles, 1998, Biochemistry.

Ab initio MO calculations and 17O NMR at natural abundance of para‐substituted acetophenones

D. Craik, M. Sadek, R. Brownlee, 1983 .

The relationship between 19F and 13C substituent chemical shifts and electron densities. 2—p‐phenylacetyl fluorides

D. Craik, R. Brownlee, 1981 .

Kalata B1 and Kalata B2 Have a Surfactant-Like Activity in Phosphatidylethanolomine-Containing Lipid Membranes.

D. Craik, B. Martinac, B. Cornell, 2017, Langmuir : the ACS journal of surfaces and colloids.

Designing macrocyclic disulfide-rich peptides for biotechnological applications

D. Craik, Conan K. Wang, 2018, Nature Chemical Biology.

Discovery and applications of naturally occurring cyclic peptides.

D. Craik, Louise Thorstholm, 2012, Drug discovery today. Technologies.

New alkaloids from Pandanus amaryllifolius.

D. Craik, M. Garson, A. Salim, 2004, Journal of natural products.

New indole alkaloids from the bark of Alstonia scholaris.

D. Craik, M. Garson, A. Salim, 2004, Journal of natural products.

New indole alkaloids from the roots of Ochrosia acuminata.

D. Craik, M. Garson, A. Salim, 2004, Journal of natural products.

Synthesis, DNA binding interactions and biological activity of bis platinum (II) complexes of N,N,N',N'-tetrakis(2-aminoethyl)diamines.

D. Craik, W. Denny, B. Palmer, 1992, Anti-cancer drug design.

α-Conotoxin ImI incorporating stable cystathionine bridges maintains full potency and identical three-dimensional structure.

D. Craik, I. Vetter, R. Lewis, 2011, Journal of the American Chemical Society.

Cyclic Peptides via Ligation Methods

D. Craik, Tristan J. Tyler, 2021 .

Exploring the Sequence Diversity of Cyclotides from Vietnamese Viola Species.

D. Craik, Q. Kaas, Yen‐Hua Huang, 2020, Journal of natural products.

Cyclotides: From Structure to Function.

D. Craik, S. D. de Veer, M. Kan, 2019, Chemical reviews.

Ribosomally-synthesised cyclic peptides from plants as drug leads and pharmaceutical scaffolds.

D. Craik, Fabian B. H. Rehm, H. Peacock, 2017, Bioorganic & medicinal chemistry.

Transcriptomic screening for cyclotides and other cysteine-rich proteins in the metallophyte Viola baoshanensis.

D. Craik, Zebo Huang, Bing Yang, 2015, Journal of plant physiology.

Discovery of Peptide Drugs from Natural Sources

D. Craik, S. Henriques, 2015 .

Joseph Rudinger memorial lecture: Discovery and applications of cyclotides

D. Craik, 2013, Journal of peptide science : an official publication of the European Peptide Society.

Cyclotides Associate with Leaf Vasculature and Are the Products of a Novel Precursor in Petunia (Solanaceae)*

R. Lyons, D. Craik, M. Colgrave, 2012, The Journal of Biological Chemistry.

Cyclotides as a basis for drug design

Masa Cemazar, David J Craik, D. Craik, 2012, Expert opinion on drug discovery.

Host-Defense Activities of Cyclotides

D. Craik, 2012, Toxins.

Identification and Structural Characterization of Novel Cyclotide with Activity against an Insect Pest of Sugar Cane*

D. Craik, O. Franco, S. C. Dias, 2011, The Journal of Biological Chemistry.

NMR and protein structure in drug design: application to cyclotides and conotoxins

D. Craik, K. Rosengren, S. Henriques, 2011, European Biophysics Journal.

Plant peptide toxins from nonmarine environments

D. Craik, Jan-Christoph Westermann, 2010 .

Structural and biochemical characteristics of the cyclotide kalata B5 from Oldenlandia affinis.

D. Craik, M. Plan, K. Rosengren, 2010, Biopolymers.

Distribution and Evolution of Circular Miniproteins in Flowering Plants[W]

D. Craik, M. Trabi, A. Kinghorn, 2008, The Plant Cell Online.

Formation of cyclotides and variations in cyclotide expression in Oldenlandia affinis suspension cultures

D. Craik, C. Gruber, H. Dörnenburg, 2007, Applied Microbiology and Biotechnology.

Potential therapeutic applications of the cyclotides and related cystine knot mini-proteins

Norelle L Daly, David J Craik, D. Craik, 2007, Expert opinion on investigational drugs.

NMR as a tool for elucidating the structures of circular and knotted proteins.

D. Craik, N. Daly, 2007, Molecular bioSystems.

Insecticidal plant cyclotides and related cystine knot toxins.

Marilyn A. Anderson, Masa Cemazar, David J Craik, 2007, Toxicon : official journal of the International Society on Toxinology.

Discovery of Cyclotide-Like Protein Sequences in Graminaceous Crop Plants: Ancestral Precursors of Circular Proteins?[W]

Marilyn A. Anderson, D. Craik, R. Burton, 2006, The Plant Cell Online.

The cyclotide family of circular miniproteins: nature's combinatorial peptide template.

Masa Cemazar, Norelle L Daly, David J Craik, 2006, Biopolymers.

A Continent of Plant Defense Peptide Diversity: Cyclotides in Australian Hybanthus (Violaceae)w⃞

Michelle L Colgrave, Ulf Göransson, David J Craik, 2005, The Plant Cell Online.

Isolation and Characterization of Novel Cyclotides from Viola hederaceae

K. Gustafson, D. Craik, K. Rosengren, 2005, Journal of Biological Chemistry.

Conserved Structural and Sequence Elements Implicated in the Processing of Gene-encoded Circular Proteins*

Marilyn A. Anderson, Cameron V. Jennings, D. Craik, 2004, Journal of Biological Chemistry.

The role of the cyclic peptide backbone in the anti‐HIV activity of the cyclotide kalata B1

K. Gustafson, D. Craik, N. Daly, 2004, FEBS letters.

Tissue-Specific Expression of Head-to-Tail Cyclized Miniproteins in Violaceae and Structure Determination of the Root Cyclotide Viola hederacea root cyclotide1

D. Craik, M. Trabi, 2004, The Plant Cell Online.

Solution structure of the cyclotide palicourein: implications for the development of a pharmaceutical framework.

K. Gustafson, D. Craik, N. Daly, 2004, Structure.

A Comparison of the Self-association Behavior of the Plant Cyclotides Kalata B1 and Kalata B2 via Analytical Ultracentrifugation*

D. Craik, M. Trabi, A. Nourse, 2004, Journal of Biological Chemistry.

Tissue-Specific Expression of Head-to-Tail Cyclized Miniproteins in Violaceae and Structure Determination of the Root Cyclotide Viola hederacea root cyclotide

D. Craik, M. Trabi, 2004 .

Disulfide Mapping of the Cyclotide Kalata B1

Ulf Göransson, David J Craik, D. Craik, 2003, Journal of Biological Chemistry.

Structure‐Function Studies of the Plant Cyclotides: The Role of a Circular Protein Backbone

D. Craik, N. Daly, R. Clark, 2003 .

Circular proteins--no end in sight.

David J Craik, D. Craik, M. Trabi, 2002, Trends in biochemical sciences.

Substituent Effects on Nuclear Shielding

D. Craik, 1984 .

Substituent effects on the carbon-13 N.M.R. chemical shifts of side-chain carbons in aromatic systems

D. Craik, R. Brownlee, J. Bromilow, 1977 .

Substituent Effects On N-15 and O-17 Chemical-Shifts in Nitrobenzenes - Correlations with Electron-Densities

G. C. Levy, D. Craik, R. Brownlee, 2002 .

Converting peptides into drugs targeting intracellular protein-protein interactions.

D. Craik, S. Henriques, G. Philippe, 2021, Drug discovery today.

Carbon-13 N.M.R. Studies of Carbocations. III. An Investigation of the Variation of ipso-Substituent Chemical Shifts with Electron Demand in 1,4-Disubstituted Benzenes

D. Craik, R. Brownlee, D. P. Kelly, 1979 .

Carbon-13 substituent chemical shifts in the side-chain carbons of aromatic systems: the importance of π-polarization in determining chemical shifts

D. Craik, M. Sadek, R. Brownlee, 1981 .

COERCIVITY MECHANISMS IN OXIDE MAGNETS

D. Craik, E. Hill, 1977 .

Microcin J25 has a threaded sidechain-to-backbone ring structure and not a head-to-tail cyclized backbone.

Ulf Göransson, Norelle L Daly, David J Craik, 2003, Journal of the American Chemical Society.

Solving the alpha-conotoxin folding problem: efficient selenium-directed on-resin generation of more potent and stable nicotinic acetylcholine receptor antagonists.

P. T. Choy, D. Craik, Jennifer L. Martin, 2010, Journal of the American Chemical Society.

The chemistry of cyclotides.

D. Craik, A. C. Conibear, 2011, The Journal of organic chemistry.

Naturally occurring circular proteins: distribution, biosynthesis and evolution.

D. Craik, L. Cascales, 2010, Organic & biomolecular chemistry.

Discovery, synthesis, and structure-activity relationships of conotoxins.

D. Craik, Q. Kaas, R. Lewis, 2014, Chemical reviews.

α-Selenoconotoxins, a New Class of Potent α7 Neuronal Nicotinic Receptor Antagonists*

D. Craik, David John Adams, N. Daly, 2006, Journal of Biological Chemistry.

Protein folding: Turbo-charged crosslinking.

D. Craik, 2012, Nature chemistry.

Structures of Naturally Occurring Circular Proteins from Bacteria

D. Craik, M. Trabi, K. Rosengren, 2003, Journal of bacteriology.

Chemistry. Seamless proteins tie up their loose ends.

D. Craik, 2006, Science.

How do cyclotides exert their mode of action? the importance of cell membranes on their diverse activities

D. Craik, Yen‐Hua Huang, S. Henriques, 2009 .

Engineering cyclic peptide toxins.

D. Craik, R. Clark, 2012, Methods in enzymology.

Native chemical ligation applied to the synthesis and bioengineering of circular peptides and proteins.

David J Craik, D. Craik, R. Clark, 2010, Biopolymers.

Ultra‐Stable Peptide Scaffolds for Protein Engineering—Synthesis and Folding of the Circular Cystine Knotted Cyclotide Cycloviolacin O2

D. Craik, U. Göransson, R. Clark, 2008 .

Computer-aided design of mastoparan-like peptides enables the generation of non-toxic variants with extended antibacterial properties.

Suzana M. Ribeiro, Karen G. N. Oshiro, T. Lu, 2019, Journal of medicinal chemistry.

Problems in the assessment of magnesium depletion in the rat by in vivo 31P NMR

D. Craik, R. Wellard, M. Kneen, 1988, Magnetic resonance in medicine.

Sunflower trypsin inhibitor-1.

Horst Joachim Schirra, David J Craik, D. Craik, 2004, Current protein & peptide science.

Cyclotides as natural anti‐HIV agents

David J Craik, K. Gustafson, D. Craik, 2008, Biopolymers.

Cyclic Penta- and Hexaleucine Peptides without N-Methylation Are Orally Absorbed.

Martin J. Stoermer, D. Craik, David A. Price, 2014, ACS medicinal chemistry letters.

Difficult macrocyclizations: new strategies for synthesizing highly strained cyclic tetrapeptides.

Douglas A. Horton, Martin Scanlon, D. Craik, 2003, Organic letters.

Insights into the molecular flexibility of θ-defensins by NMR relaxation analysis.

D. Craik, K. Rosengren, Conan K. Wang, 2014, The journal of physical chemistry. B.

Solution Structure, Membrane Interactions, and Protein Binding Partners of the Tetraspanin Sm-TSP-2, a Vaccine Antigen from the Human Blood Fluke Schistosoma mansoni*

A. Loukas, D. Craik, K. Rosengren, 2014, The Journal of Biological Chemistry.

The cell wall galactans from Australian representatives of the genus Meristotheca (Solieriaceae, Rhodophyta)

D. Craik, A. Chiovitti, G. Kraft, 2003 .

Oxytocic plant cyclotides as templates for peptide G protein-coupled receptor ligand design

Susan Wray, Terry J. Smith, Michael Freissmuth, 2013, Proceedings of the National Academy of Sciences.

Dermatophytic defensin with antiinfective potential

D. Craik, Shunyi Zhu, P. Harvey, 2012, Proceedings of the National Academy of Sciences.

Isolation and Characterization of Cyclotides from Brazilian Psychotria: Significance in Plant Defense and Co-occurrence with Antioxidant Alkaloids.

D. Craik, A. Fett-Neto, H. Matsuura, 2016, Journal of natural products.

Isolation and characterization of cytotoxic cyclotides from Viola philippica

D. Craik, G. Zeng, N. Tan, 2011, Peptides.

The Chemistry and Biology of Theta Defensins

D. Craik, A. C. Conibear, 2014, Angewandte Chemie.

Plant-Derived Decapeptide OSIP108 Interferes with Candida albicans Biofilm Formation without Affecting Cell Viability

D. Craik, M. Fröhlich, T. Coenye, 2014, Antimicrobial Agents and Chemotherapy.

albicans biofilm formation without affecting cell viability 2

D. Craik, T. Coenye, O. Cheneval, 2014 .

Solution structure by NMR of circulin A: a macrocyclic knotted peptide having anti-HIV activity.

K. Gustafson, M. Boyd, D. Craik, 1999, Journal of molecular biology.

Protein disulfide isomerase: the structure of oxidative folding.

Masa Cemazar, David J Craik, Begoña Heras, 2006, Trends in biochemical sciences.

Anomalous observations on the approach to ferromagnetic saturation

D. Craik, 1967 .

Cyclotides as templates in drug design.

David J Craik, D. Craik, S. Henriques, 2010, Drug discovery today.

The Vast Structural Diversity of Antimicrobial Peptides.

D. Craik, J. Koehbach, 2019, Trends in pharmacological sciences.

Isolation and characterization of peptides from Momordica cochinchinensis seeds.

D. Craik, R. Lewis, Conan K. Wang, 2009, Journal of Natural Products.

Conformational Flexibility Is a Determinant of Permeability for Cyclosporin.

D. Craik, P. Harvey, Q. Kaas, 2018, The journal of physical chemistry. B.

Cyclic peptide oral bioavailability: Lessons from the past

D. Craik, Conan K. Wang, 2016, Biopolymers.

The use of dietary loading of 133Cs as a potassium substitute in NMR studies of tissues

D. Craik, B. Shehan, R. Wellard, 1993, Magnetic resonance in medicine.

Structural and Functional Analysis of Human Liver‐Expressed Antimicrobial Peptide 2

D. Craik, R. Clark, C. Tan, 2010, Chembiochem : a European journal of chemical biology.

Solution structure, aggregation behavior, and flexibility of human relaxin-2.

D. Craik, J. Wade, K. Rosengren, 2015, ACS chemical biology.

Transmission of substituent effects via molecular lines of force: defense of the DSP method and an illustration of its use in explaining pi polarization

D. Craik, M. Sadek, R. Brownlee, 1982 .

Discovery, structure, function, and applications of cyclotides: circular proteins from plants.

D. Craik, J. Weidmann, 2016, Journal of experimental botany.

A new family of cystine knot peptides from the seeds of Momordica cochinchinensis

D. Craik, G. Zeng, N. Daly, 2013, Peptides.

Identification and Characterization of a New Family of Cell-penetrating Peptides

M. Sweet, D. Craik, Yen‐Hua Huang, 2011, The Journal of Biological Chemistry.

Characterising the Subsite Specificity of Urokinase‐Type Plasminogen Activator and Tissue‐Type Plasminogen Activator using a Sequence‐Defined Peptide Aldehyde Library

J. Whisstock, D. Craik, R. Law, 2018, Chembiochem : a European journal of chemical biology.

Bioactive Compounds Isolated from Neglected Predatory Marine Gastropods

D. Craik, Q. Kaas, C. Schroeder, 2018, Marine drugs.

Pharmaceutical Applications of NMR

D. Craik, M. Scanlon, 2000 .

Structure determination of the three disulfide bond isomers of alpha-conotoxin GI: a model for the role of disulfide bonds in structural stability.

D. Craik, P. Alewood, J. Gehrmann, 1998, Journal of molecular biology.

Discovery, structure and biological activities of cyclotides.

D. Craik, K. Rosengren, N. Daly, 2004, Advanced drug delivery reviews.

Cyclotides: macrocyclic peptides with applications in drug design and agriculture

D. Craik, N. Daly, J. Mylne, 2009, Cellular and Molecular Life Sciences.

Conotoxins: Chemistry and Biology.

D. Craik, Q. Kaas, R. Lewis, 2019, Chemical reviews.

Anomalies in the Reduction of the Schiff-Bases 5-(diethylamino)-2-(phenyliminomethyl)phenol and 2-[(4-Diethylaminophenyl)iminomethyl]-Phenol and Their Crystal-Structures

D. Craik, R. Gable, M. Mackay, 1990 .

Stability studies of oxazolidine-based compounds using 1H NMR spectroscopy.

D. Craik, M. Iskander, G. P. Moloney, 2010, Journal of pharmaceutical sciences.

Solution Structure of μ-Conotoxin PIIIA, a Preferential Inhibitor of Persistent Tetrodotoxin-sensitive Sodium Channels*

D. Craik, P. Gage, David John Adams, 2002, The Journal of Biological Chemistry.

Synthesis, NMR studies and conformational analysis of oxazolidine derivatives of the β-adrenoreceptor antagonists metoprolol, atenolol and timolol

D. Craik, T. Nero, M. Iskander, 1998 .

Interaction of Hoechst 33258 with the minor groove of the A + T-rich DNA duplex d(GGTAATTACC)2 studied in solution by NMR spectroscopy.

D. Craik, M. Searle, K. Embrey, 1993, European journal of biochemistry.

NMR Studies of Ligand-Macromolecule Interactions

D. Craik, K. A. Higgins, 1991 .

Characterization of the sequential non‐covalent and covalent interactions of the antitumour antibiotic hedamycin with double stranded DNA by NMR spectroscopy

D. Craik, W. Bicknell, S. Pavlopoulos, 1999, Journal of molecular recognition : JMR.

Evolutionary Origins of a Bioactive Peptide Buried within Preproalbumin[C][W]

D. Craik, K. Rosengren, E. Schilling, 2014, Plant Cell.

Computational and Functional Mapping of Human and Rat α6β4 Nicotinic Acetylcholine Receptors Reveals Species-Specific Ligand-Binding Motifs.

D. Craik, Q. Kaas, J. McIntosh, 2021, Journal of medicinal chemistry.

Characterization of a Bioactive Acyclotide from Palicourea rigida.

D. Craik, O. Franco, W. F. Porto, 2016, Journal of natural products.

Elucidation of the primary and three-dimensional structure of the uterotonic polypeptide kalata B1.

I. Campbell, D. Craik, D. Norman, 1995, Biochemistry.

Histidine-Rich Defensins from the Solanaceae and Brasicaceae Are Antifungal and Metal Binding Proteins

D. Craik, Thomas M A Shafee, P. Harvey, 2020, Journal of fungi.

CyBase: a database of cyclic protein sequences and structures, with applications in protein discovery and engineering

Conan K. L. Wang, David J. Craik, Quentin Kaas, 2007, Nucleic Acids Res..

Beta-arrestin 2 is required for complement C1q expression in macrophages and constrains factor-independent survival.

D. Hume, M. Sweet, D. Craik, 2009, Molecular immunology.

Molecular basis for the resistance of an insect chymotrypsin to a potato type II proteinase inhibitor

D. Craik, M. Anderson, Q. Kaas, 2010, Proceedings of the National Academy of Sciences.

Circular Proteins in Plants

D. Craik, N. Daly, D J Craik, 2001, The Journal of Biological Chemistry.

Insect peptides with improved protease‐resistance protect mice against bacterial infection

D. Craik, R. Hoffmann, J. Wade, 2008, Protein science : a publication of the Protein Society.

Inhibition of Neuronal Nicotinic Acetylcholine Receptor Subtypes by α-Conotoxin GID and Analogues*

D. Craik, David John Adams, R. Lewis, 2009, Journal of Biological Chemistry.

Constrained Cyclic Peptides as Immunomodulatory Inhibitors of the CD2:CD58 Protein-Protein Interaction.

D. Craik, T. Durek, V. Taneja, 2016, ACS chemical biology.

Manipulation of a spider peptide toxin alters its affinity for lipid bilayers and potency and selectivity for voltage-gated sodium channel subtype 1.7

D. Craik, I. Vetter, C. Schroeder, 2020, The Journal of Biological Chemistry.

Structural parameters modulating the cellular uptake of disulfide-rich cyclic cell-penetrating peptides: MCoTI-II and SFTI-1.

D. Craik, S. Henriques, Conan K. Wang, 2014, European journal of medicinal chemistry.

ConoServer: updated content, knowledge, and discovery tools in the conopeptide database

David J. Craik, Quentin Kaas, Rilei Yu, 2011, Nucleic Acids Res..

In Silico Design of MDM2‐Targeting Peptides from a Naturally Occurring Constrained Peptide

D. Craik, P. Harvey, Q. Kaas, 2019, ChemMedChem.

Cell membrane composition drives selectivity and toxicity of designed cyclic helix-loop-helix peptides with cell penetrating and tumor suppressor properties.

D. Craik, J. Weidmann, Yen‐Hua Huang, 2019, ACS chemical biology.

The role of disulfide bonds in the structure and function of murine epidermal growth factor (mEGF)

D. Craik, A. Burgess, F. Walker, 2005, Growth factors.

Chemical synthesis, characterization and activity of RK‐1, a novel α‐defensin‐related peptide

D. Craik, J. Wade, S. Dashper, 2000, Journal of peptide science : an official publication of the European Peptide Society.

Development of cell‐penetrating peptide‐based drug leads to inhibit MDMX:p53 and MDM2:p53 interactions

D. Craik, O. Cheneval, Yen‐Hua Huang, 2016, Biopolymers.

A Novel Quantitative Kinase Assay Using Bacterial Surface Display and Flow Cytometry

Jennifer A. Getz, D. Craik, Yen‐Hua Huang, 2013, PloS one.

Synthesis of an Analog of the Thyroid Hormone-binding Protein Transthyretin via Regioselective Chemical Ligation*

D. Craik, J. Wilce, P. Alewood, 2001, The Journal of Biological Chemistry.

Peptide-based LDH5 inhibitors enter cancer cells and impair proliferation

D. Craik, Q. Kaas, S. Henriques, 2022, Cellular and Molecular Life Sciences.

Conopressin-T from Conus tulipa Reveals an Antagonist Switch in Vasopressin-like Peptides*

D. Craik, R. Lewis, G. Guillon, 2008, Journal of Biological Chemistry.

Magnetic Interaction Domains

D. Craik, E. Isaac, 1960 .

An environmentally sustainable biomimetic production of cyclic disulfide-rich peptides

D. Craik, David John Adams, T. Durek, 2020, Green Chemistry.

Processing of a 22 kDa precursor protein to produce the circular protein tricyclon A.

David J Craik, D. Craik, J. Mulvenna, 2005, Structure.

Modified horseshoe crab peptides target and kill bacteria inside host cells

M. Sweet, D. Craik, R. Kapetanovic, 2021, Cellular and Molecular Life Sciences.

Plant cyclotides: A unique family of cyclic and knotted proteins that defines the cyclic cystine knot structural motif.

D. Craik, N. Daly, C. Waine, 1999, Journal of molecular biology.

Single Amino Acid Substitutions in α-Conotoxin PnIA Shift Selectivity for Subtypes of the Mammalian Neuronal Nicotinic Acetylcholine Receptor*

D. Craik, David John Adams, R. Lewis, 1999, The Journal of Biological Chemistry.

Single amino acid substitutions in alpha-conotoxin PnIA shift selectivity for subtypes of the mammalian neuronal nicotinic acetylcholine receptor.

D. Craik, David John Adams, R. Lewis, 1999, Journal of Biological Chemistry.

Periplasmic Expression of 4/7 α-Conotoxin TxIA Analogs in E. coli Favors Ribbon Isomer Formation – Suggestion of a Binding Mode at the α7 nAChR

D. Craik, Q. Kaas, A. Nicke, 2019, Front. Pharmacol..

Key Residues in the Nicotinic Acetylcholine Receptor β2 Subunit Contribute to α-Conotoxin LvIA Binding*

D. Craik, Q. Kaas, J. McIntosh, 2015, The Journal of Biological Chemistry.

Cyclic thrombospondin-1 mimetics: grafting of a thrombospondin sequence into circular disulfide-rich frameworks to inhibit endothelial cell migration

D. Craik, N. Daly, L. Y. Chan, 2015, Bioscience reports.

Engineered protease inhibitors based on sunflower trypsin inhibitor-1 (SFTI-1) provide insights into the role of sequence and conformation in Laskowski mechanism inhibition.

D. Craik, Jonathan M. Harris, K. Rosengren, 2015, The Biochemical journal.

A novel α4/7‐conotoxin LvIA from Conus lividus that selectively blocks α3β2 vs. α6/α3β2β3 nicotinic acetylcholine receptors

D. Craik, Q. Kaas, C. Schroeder, 2014, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

RegIIA: an α4/7-conotoxin from the venom of Conus regius that potently blocks α3β4 nAChRs.

D. Craik, David John Adams, N. Daly, 2012, Biochemical pharmacology.

EGF-like and Other Disulfide-rich Micro-domains as Therapeutic Scaffolds.

D. Craik, Conan K. Wang, Benjamin J. Tombling, 2019, Angewandte Chemie.

1H NMR analysis of fibril-forming peptide fragments of transthyretin.

D. Craik, J. A. Jarvis, D J Craik, 2009, International journal of peptide and protein research.

The evolution of Momordica cyclic peptides.

D. Craik, Q. Kaas, H. Schaefer, 2015, Molecular biology and evolution.

Overview of NMR in Drug Design

David J. Craik, Hayden Peacock, D. Craik, 2017 .

Cyclic MrIA: a stable and potent cyclic conotoxin with a novel topological fold that targets the norepinephrine transporter.

Michelle L Colgrave, Norelle L Daly, David J Craik, 2006, Journal of medicinal chemistry.

Purification and characterization of a plant antimicrobial peptide expressed in Escherichia coli.

D. Craik, J. Manners, D. Maclean, 1999, Protein expression and purification.

Improving on nature: making a cyclic heptapeptide orally bioavailable.

Spiros Liras, David J Craik, D. Craik, 2014, Angewandte Chemie.

Evaluation of the in vitro Antitumor Activity of Nanostructured Cyclotides in Polymers of Eudragit® L 100-55 and RS 30 D

D. Craik, O. Franco, O. N. Silva, 2019, Letters in Drug Design & Discovery.

Cloning, synthesis, and characterization of αO-conotoxin GeXIVA, a potent α9α10 nicotinic acetylcholine receptor antagonist

D. Craik, P. Harvey, Q. Kaas, 2015, Proceedings of the National Academy of Sciences.

Kalata B8, a novel antiviral circular protein, exhibits conformational flexibility in the cystine knot motif.

Norelle L Daly, David J Craik, D. Craik, 2006, The Biochemical journal.

Development of Novel Melanocortin Receptor Agonists Based on the Cyclic Peptide Framework of Sunflower Trypsin Inhibitor-1.

Philipp M. Cromm, A. Plowright, D. Craik, 2018, Journal of medicinal chemistry.

Protocols for measuring the stability and cytotoxicity of cyclotides.

D. Craik, Yen‐Hua Huang, M. Kan, 2022, Methods in Enzymology.

Cyclotide Structures Revealed by NMR, with a Little Help from X‐ray Crystallography

D. Craik, P. Harvey, Conan K. Wang, 2020, Chembiochem : a European journal of chemical biology.

A Practical Guide to Structural Aspects of Macrocycles (NMR, X‐Ray, and Modeling)

David J. Craik, Quentin Kaas, Conan K. Wang, 2017 .

Gene coevolution and regulation lock cyclic plant defence peptides to their targets.

D. Craik, S. Henriques, M. Jackson, 2016, The New phytologist.

Semienzymatic Cyclization of Disulfide-rich Peptides Using Sortase A*

D. Craik, C. Schroeder, Yen‐Hua Huang, 2014, The Journal of Biological Chemistry.

The self-association of the cyclotide kalata B2 in solution is guided by hydrophobic interactions.

D. Craik, P. Harvey, K. Rosengren, 2013, Biopolymers.

Cyclotides as grafting frameworks for protein engineering and drug design applications.

David J Craik, D. Craik, L. Y. Chan, 2013, Biopolymers.

Design, Synthesis, Structural and Functional Characterization of Novel Melanocortin Agonists Based on the Cyclotide Kalata B1*

D. Craik, T. Andresen, B. Wulff, 2012, The Journal of Biological Chemistry.

A Synthetic Mirror Image of Kalata B1 Reveals that Cyclotide Activity Is Independent of a Protein Receptor

K. Gustafson, D. Craik, M. Aguilar, 2011, Chembiochem : a European journal of chemical biology.

Discovery of cyclotides in the fabaceae plant family provides new insights into the cyclization, evolution, and distribution of circular proteins.

D. Craik, N. Daly, M. Colgrave, 2011, ACS chemical biology.

Cystine knot folding in cyclotides

D. Craik, N. Daly, U. Göransson, 2011 .

Structure and Activity of the Leaf-Specific Cyclotide vhl-2

D. Craik, N. Daly, Bin Chen, 2010 .

Lysine-scanning Mutagenesis Reveals an Amendable Face of the Cyclotide Kalata B1 for the Optimization of Nematocidal Activity*

D. Craik, Yen‐Hua Huang, M. Colgrave, 2010, The Journal of Biological Chemistry.

Cyclotides are a component of the innate defense of Oldenlandia affinis.

D. Craik, Conan K. Wang, J. Mylne, 2010, Biopolymers.

The Biological Activity of the Prototypic Cyclotide Kalata B1 Is Modulated by the Formation of Multimeric Pores*

D. Craik, Yen‐Hua Huang, B. Martinac, 2009, The Journal of Biological Chemistry.

Dissecting the oxidative folding of circular cystine knot miniproteins.

D. Craik, N. Daly, S. Gunasekera, 2009, Antioxidants & redox signaling.

Oxidative folding of cyclic cystine knot proteins.

D. Craik, C. Gruber, Christian W. Gruber, 2008, Antioxidants & redox signaling.

A novel suite of cyclotides from Viola odorata: sequence variation and the implications for structure, function and stability

D. Craik, M. Colgrave, D. Ireland, 2006 .

A novel suite of cyclotides from Viola odorata: sequence variation and the implications for structure, function and stability.

D. Craik, M. Colgrave, D. Ireland, 2006, Biochemical Journal.

Discovery and characterization of a linear cyclotide from Viola odorata: implications for the processing of circular proteins.

D. Craik, N. Daly, M. Colgrave, 2006, Journal of molecular biology.

Structural plasticity of the cyclic-cystine-knot framework: implications for biological activity and drug design.

D. Craik, N. Daly, R. Clark, 2006, The Biochemical journal.

New Cyclotide Precursor Sequences

D. Craik, L. Sando, R. Bharathi, 2006 .

Isolation, solution structure, and insecticidal activity of kalata B2, a circular protein with a twist: do Möbius strips exist in nature?

Clement Waine, Cameron V. Jennings, Martin J Scanlon, 2005, Biochemistry.

Structure of Circulin B and Implications for Antimicrobial Activity of the Cyclotides

K. Gustafson, D. Craik, N. Daly, 2004, International Journal of Peptide Research and Therapeutics.

Linearization of a naturally occurring circular protein maintains structure but eliminates hemolytic activity.

D. Craik, N. Daly, R. Clark, 2003, Biochemistry.

Biosynthesis and insecticidal properties of plant cyclotides: The cyclic knotted proteins from Oldenlandia affinis

Clement Waine, Cameron V. Jennings, Marilyn Anderson, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Acyclic Permutants of Naturally Occurring Cyclic Proteins

David J. Craik, Norelle L. Daly, D. Craik, 2000, The Journal of Biological Chemistry.

1H-NMR structural studies of a cystine-linked peptide containing residues 71-93 of transthyretin and effects of a Ser84 substitution implicated in familial amyloidotic polyneuropathy.

D. Craik, J. Wilce, J. Wade, 1999, European journal of biochemistry.

Discovery and optimization of peptide macrocycles

D. Craik, A. M. White, 2016, Expert opinion on drug discovery.

Chemical Synthesis of Naturally-Occurring Cyclic Mini-Proteins from Plants and Animals

D. Craik, A. C. Conibear, 2011 .

Isolation and characterization of cytotoxic cyclotides from Viola tricolor

D. Craik, G. Zeng, N. Tan, 2010, Peptides.

Capped acyclic permutants of the circular protein kalata B1

D. Craik, N. Daly, Shane M. Simonsen, 2004, FEBS letters.

Identification of candidates for cyclotide biosynthesis and cyclisation by expressed sequence tag analysis of Oldenlandia affinis

D. Craik, Q. Kaas, J. Suda, 2010, BMC Genomics.

Small cyclic sodium channel inhibitors.

D. Craik, I. Vetter, J. Tytgat, 2020, Biochemical pharmacology.

Efficient enzymatic cyclization of an inhibitory cystine knot‐containing peptide

D. Craik, O. Cheneval, Q. Kaas, 2016, Biotechnology and bioengineering.

α-Conotoxin Vc1.1 inhibits human dorsal root ganglion neuroexcitability and mouse colonic nociception via GABAB receptors

Paul E. Miller, D. Craik, David John Adams, 2016, Gut.

Less is More: Design of a Highly Stable Disulfide-Deleted Mutant of Analgesic Cyclic α-Conotoxin Vc1.1

D. Craik, David John Adams, Q. Kaas, 2015, Scientific Reports.

Effects of cyclization on stability, structure, and activity of α-conotoxin RgIA at the α9α10 nicotinic acetylcholine receptor and GABA(B) receptor.

D. Craik, David John Adams, N. Daly, 2011, Journal of medicinal chemistry.

Analgesic α-Conotoxins Vc1.1 and Rg1A Inhibit N-Type Calcium Channels in Rat Sensory Neurons via GABAB Receptor Activation

Alison Haythornthwaite, David J Craik, David J Adams, 2008, The Journal of Neuroscience.

The Synthesis, Structural Characterization, and Receptor Specificity of the α-Conotoxin Vc1.1*

D. Craik, David John Adams, R. Clark, 2006, Journal of Biological Chemistry.

Engineering stable peptide toxins by means of backbone cyclization: stabilization of the alpha-conotoxin MII.

Norelle L Daly, David J Craik, Harald Fischer, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Interaction of Tarantula Venom Peptide ProTx-II with Lipid Membranes Is a Prerequisite for Its Inhibition of Human Voltage-gated Sodium Channel NaV1.7*

A. Mark, D. Craik, I. Vetter, 2016, The Journal of Biological Chemistry.

NaV1.6 regulates excitability of mechanosensitive sensory neurons

S. Dib-Hajj, S. Waxman, D. Craik, 2019, The Journal of physiology.

αO-Conotoxin GeXIVA disulfide bond isomers exhibit differential sensitivity for various nicotinic acetylcholine receptors but retain potency and selectivity for the human α9α10 subtype

D. Craik, Q. Kaas, J. McIntosh, 2017, Neuropharmacology.

Structure-Activity Studies of Cysteine-Rich α-Conotoxins that Inhibit High-Voltage-Activated Calcium Channels via GABA(B) Receptor Activation Reveal a Minimal Functional Motif.

D. Craik, David John Adams, S. Brierley, 2016, Angewandte Chemie.

Determination of the α-conotoxin Vc1.1 binding site on the α9α10 nicotinic acetylcholine receptor.

D. Craik, David John Adams, Q. Kaas, 2013, Journal of medicinal chemistry.

Therapeutic potential of conopeptides.

David J Craik, D. Craik, C. Schroeder, 2012, Future medicinal chemistry.

The engineering of an orally active conotoxin for the treatment of neuropathic pain.

David J Craik, David J Adams, D. Craik, 2010, Angewandte Chemie.

Where cone snails and spiders meet: design of small cyclic sodium‐channel inhibitors

D. Craik, P. Herdewijn, S. Heinemann, 2018, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Enzymatic C‐to‐C Protein Ligation

D. Craik, T. Durek, S. D. de Veer, 2022, Angewandte Chemie.

Rational Design of Potent Peptide Inhibitors of the PD-1:PD-L1 Interaction for Cancer Immunotherapy.

D. Craik, Yen‐Hua Huang, B. Collins, 2021, Journal of the American Chemical Society.

Structure-Activity Studies Reveal the Molecular Basis for GABAB-Receptor Mediated Inhibition of High Voltage-Activated Calcium Channels by α-Conotoxin Vc1.1.

D. Craik, David John Adams, S. Brierley, 2018, ACS chemical biology.

Structure and Activity of α-Conotoxin PeIA at Nicotinic Acetylcholine Receptor Subtypes and GABAB Receptor-coupled N-type Calcium Channels*

D. Craik, David John Adams, N. Daly, 2011, The Journal of Biological Chemistry.

Critical Residue Properties for Potency and Selectivity of α-Conotoxin RgIA Towards α9α10 Nicotinic Acetylcholine Receptors.

D. Craik, P. Harvey, J. Gajewiak, 2020, Biochemical pharmacology.

Backbone cyclization of analgesic conotoxin GeXIVA facilitates direct folding of the ribbon isomer

D. Craik, David John Adams, P. Harvey, 2017, The Journal of Biological Chemistry.

Identifying Key Amino Acid Residues That Affect α-Conotoxin AuIB Inhibition of α3β4 Nicotinic Acetylcholine Receptors*

D. Craik, David John Adams, A. Hung, 2013, The Journal of Biological Chemistry.

Conotoxin-based leads in drug design

D. Craik, Muharrem Akcan, 2011 .

Short Cationic Peptide Derived from Archaea with Dual Antibacterial Properties and Anti-Infective Potential.

Karen G. N. Oshiro, T. Lu, D. Craik, 2019, ACS infectious diseases.

A pyruvated carrageenan from Australian specimens of the red alga Sarconema filiforme

A. Bacic, R. Furneaux, D. Craik, 1998 .

BETA/KAPPA‐CARRAGEENANS AS EVIDENCE FOR CONTINUED SEPARATION OF THE FAMILIES DICRANEMATACEAE AND SARCODIACEAE (GIGARTINALES, RHODOPHYTA) 1

A. Bacic, D. Craik, S. Munro, 1993 .

Lengths of the C-Terminus and Interconnecting Loops Impact Stability of Spider-Derived Gating Modifier Toxins

D. Craik, C. Schroeder, Yen‐Hua Huang, 2017, Toxins.

Rational domestication of a plant-based recombinant expression system expands its biosynthetic range

D. Craik, M. Jackson, L. Y. Chan, 2021, bioRxiv.

Increased Valency Improves Inhibitory Activity of Peptides Targeting Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9)

D. Craik, Conan K. Wang, C. Lammi, 2021, Chembiochem : a European journal of chemical biology.

Novel Inhibitor Cystine Knot Peptides from Momordica charantia

D. Craik, O. Franco, G. Zeng, 2013, PloS one.

Analysis and classification of circular proteins in CyBase.

D. Craik, Q. Kaas, 2010, Biopolymers.

A Centipede Toxin Family Defines an Ancient Class of CSαβ Defensins.

D. Craik, I. Vetter, J. Tytgat, 2019, Structure.

Molecular basis for the production of cyclic peptides by plant asparaginyl endopeptidases

D. Craik, Thomas M A Shafee, Q. Kaas, 2018, Nature Communications.

Structural studies of conotoxins

Norelle L Daly, David J Craik, D. Craik, 2009, IUBMB life.

Modified defence peptides from horseshoe crab target and kill bacteria inside host cells

M. Sweet, D. Craik, R. Kapetanovic, 2021, bioRxiv.

Discovery, Characterization, and Engineering of LvIC, an α4/4-Conotoxin That Selectively Blocks Rat α6/α3β4 Nicotinic Acetylcholine Receptors.

D. Craik, P. Harvey, Q. Kaas, 2023, Journal of medicinal chemistry.

Design, synthesis, and characterization of cyclic analogues of the iron regulatory peptide hormone hepcidin.

D. Craik, E. Fung, T. Ganz, 2013, Biopolymers.

The emerging landscape of peptide-based inhibitors of PCSK9.

D. Craik, Yen‐Hua Huang, Conan K. Wang, 2021, Atherosclerosis.

The structure of a two-disulfide intermediate assists in elucidating the oxidative folding pathway of a cyclic cystine knot protein.

A. Mark, D. Craik, N. Daly, 2008, Structure.

Knots in Rings

D. Craik, E. Yulyaningsih, N. Daly, 2006, Journal of Biological Chemistry.

University of Groningen The Structure of a Two-Disulfide Intermediate Assists in Elucidating the Oxidative Folding Pathway of a Cyclic Cystine Know Protein Cernazar,

A. Mark, D. Craik, N. Daly, 2022 .

Synergistic Activity of the Plant Defensin HsAFP1 and Caspofungin against Candida albicans Biofilms and Planktonic Cultures

J. Drijfhout, D. Craik, P. Harvey, 2015, PloS one.

NMR solution structure of the RNA-binding peptide from human immunodeficiency virus (type 1) Rev.

D. Craik, D. Fairlie, M. West, 1995, Biochemistry.

Solution structures in aqueous SDS micelles of two amyloid beta peptides of A beta(1-28) mutated at the alpha-secretase cleavage site (K16E, K16F).

D. Craik, D. Fairlie, A. A. Watson, 2000, Journal of structural biology.

Structure determination of extracellular fragments of amyloid proteins involved in Alzheimer's disease and Dutch-type hereditary cerebral haemorrhage with amyloidosis.

D. Craik, K. Sorimachi, 1994, European journal of biochemistry.

Sunflower Trypsin Inhibitor-1 (SFTI-1): Sowing Seeds in the Fields of Chemistry and Biology.

D. Craik, A. M. White, S. J. Veer, 2020, Angewandte Chemie.

Chlorotoxin: Structure, activity, and potential uses in cancer therapy

D. Craik, Conan K. Wang, Paola G Ojeda, 2016, Biopolymers.

Linking molecular evolution to molecular grafting

D. Craik, Conan K. Wang, 2021, The Journal of biological chemistry.

Engineering stabilized vascular endothelial growth factor-A antagonists: synthesis, structural characterization, and bioactivity of grafted analogues of cyclotides.

D. Craik, L. Fabri, N. Daly, 2008, Journal of medicinal chemistry.

Cyclotides Suppress Human T-Lymphocyte Proliferation by an Interleukin 2-Dependent Mechanism

D. Craik, Yen‐Hua Huang, G. Schabbauer, 2013, PloS one.

Single Amino Acid Substitution in α-Conotoxin TxID Reveals a Specific α3β4 Nicotinic Acetylcholine Receptor Antagonist.

D. Craik, P. Harvey, Q. Kaas, 2018, Journal of medicinal chemistry.

α-Conotoxin [S9A]TxID Potently Discriminates between α3β4 and α6/α3β4 Nicotinic Acetylcholine Receptors.

D. Craik, P. Harvey, Q. Kaas, 2017, Journal of medicinal chemistry.

Characterization of a novel α-conotoxin TxID from Conus textile that potently blocks rat α3β4 nicotinic acetylcholine receptors.

D. Craik, P. Harvey, J. McIntosh, 2013, Journal of medicinal chemistry.

Functional evolution of scorpion venom peptides with an inhibitor cystine knot fold

D. Craik, Shunyi Zhu, P. Harvey, 2013, Bioscience reports.

Effects of Cyclization on Peptide Backbone Dynamics.

D. Craik, Conan K. Wang, Joakim E. Swedberg, 2015, The journal of physical chemistry. B.

Structural Insights into the Role of the Cyclic Backbone in a Squash Trypsin Inhibitor*

D. Craik, Jennifer L. Martin, K. Rosengren, 2013, Journal of Biological Chemistry.

Selective removal of individual disulfide bonds within a potato type II serine proteinase inhibitor from Nicotiana alata reveals differential stabilization of the reactive-site loop.

D. Craik, H. Schirra, R. Guarino, 2010, Journal of molecular biology.

A theoretical investigation of the π-polarization mechanism. The importance of localized and extended polarization

D. Craik, R. Brownlee, 1981 .

The interaction with fungal cell wall polysaccharides determines the salt tolerance of antifungal plant defensins

D. Craik, P. Harvey, K. Rosengren, 2019, Cell surface.

Structural analysis of peptide fragment 71-93 of transthyretin by NMR spectroscopy and electron microscopy: insight into amyloid fibril formation.

D. Craik, J. A. Jarvis, S. Munro, 1994, Biochemistry.

Interactions of Globular and Ribbon [γ4E]GID with α4β2 Neuronal Nicotinic Acetylcholine Receptor

D. Craik, Q. Kaas, Xiaosa Wu, 2021, Marine drugs.

NMR Structure of μ-Conotoxin GIIIC: Leucine 18 Induces Local Repacking of the N-Terminus Resulting in Reduced NaV Channel Potency

D. Craik, N. Kurniawan, David John Adams, 2018, Molecules.

Development of a O-Conotoxin Analogue with Improved Lipid Membrane Interactions and Potency for the Analgesic Sodium Channel NaV1.8

D. Craik, I. Vetter, C. Schroeder, 2016 .

Structures of muO-conotoxins from Conus marmoreus. I nhibitors of tetrodotoxin (TTX)-sensitive and TTX-resistant sodium channels in mammalian sensory neurons.

D. Craik, David John Adams, R. Lewis, 2004, The Journal of biological chemistry.

Conotoxin TVIIA, a novel peptide from the venom of Conus tulipa 1. Isolation, characterization and chemical synthesis.

D. Craik, R. Lewis, P. Alewood, 2000, European journal of biochemistry.

Nicotiana alata Defensin Chimeras Reveal Differences in the Mechanism of Fungal and Tumor Cell Killing and an Enhanced Antifungal Variant

D. Craik, Thomas M A Shafee, T. Durek, 2016, Antimicrobial Agents and Chemotherapy.

Enzymatic Cyclization of a Potent Bowman-Birk Protease Inhibitor, Sunflower Trypsin Inhibitor-1, and Solution Structure of an Acyclic Precursor Peptide*

D. Craik, L. Otvos, H. Schirra, 2003, Journal of Biological Chemistry.

Solution structures by 1H NMR of the novel cyclic trypsin inhibitor SFTI-1 from sunflower seeds and an acyclic permutant.

D. Craik, M. Anderson, L. Otvos, 2001, Journal of molecular biology.

Drug competition for thyroxine binding to transthyretin (prealbumin): comparison with effects on thyroxine-binding globulin.

D. Craik, J. Hall, C. Lim, 1989, The Journal of clinical endocrinology and metabolism.

Asparaginyl Ligases: New Enzymes for the Protein Engineer's Toolbox

D. Craik, T. Durek, Fabian B. H. Rehm, 2021, Chembiochem : a European journal of chemical biology.

Improved Asparaginyl Ligase-catalyzed Transpeptidation via Selective Nucleophile Quenching.

D. Craik, T. Durek, Fabian B. H. Rehm, 2020, Angewandte Chemie.

Site-specific sequential protein labeling catalyzed by a single recombinant ligase.

D. Craik, H. Ploegh, T. Durek, 2019, Journal of the American Chemical Society.

Efficient backbone cyclization of linear peptides by a recombinant asparaginyl endopeptidase

D. Craik, Q. Kaas, T. Durek, 2015, Nature Communications.

The acyclotide ribe 31 from Rinorea bengalensis has selective cytotoxicity and potent insecticidal properties in Drosophila

Adam Claridge‐Chang, D. Craik, P. Harvey, 2022, The Journal of biological chemistry.

Models for the binding of amiodarone to the thyroid hormone receptor

David K. Chalmers, David J. Craik, Sharon L. A. Munro, 1992, J. Comput. Aided Mol. Des..

ɑO‐Conotoxin GeXIVA isomers modulate N‐type calcium (CaV2.2) channels and inwardly‐rectifying potassium (GIRK) channels via GABAB receptor activation

D. Craik, David John Adams, Yen‐Hua Huang, 2021, Journal of Neurochemistry.

Isolation and characterization of α-conotoxin LsIA with potent activity at nicotinic acetylcholine receptors.

D. Craik, I. Vetter, David John Adams, 2013, Biochemical pharmacology.

Isolation, Structure, and Activity of GID, a Novel α4/7-Conotoxin with an Extended N-terminal Sequence*

D. Craik, David John Adams, R. Lewis, 2003, The Journal of Biological Chemistry.

Structure and Activity Studies of Disulfide-Deficient Analogues of αO-Conotoxin GeXIVA.

D. Craik, P. Harvey, Q. Kaas, 2020, Journal of medicinal chemistry.

Bibliometric Review of the Literature on Cone Snail Peptide Toxins from 2000 to 2022

D. Craik, Q. Kaas, Linh T T Nguyen, 2023, Marine drugs.

A peptide corresponding to the N‐terminal 13 residues of T4 lysozyme forms an α‐helix

D. Craik, J. Wade, M. McLeish, 1993 .

Molecular determinants of α-conotoxin potency for inhibition of human and rat α6β4 nicotinic acetylcholine receptors

D. Craik, P. Harvey, J. McIntosh, 2018, The Journal of Biological Chemistry.

Scanning mutagenesis of α-conotoxin AuIB reveals a critical residue for activity at the α3β4 nicotinic acetylcholine receptor

D. Craik, David John Adams, A. Hung, 2011 .

Atypical α-Conotoxin LtIA from Conus litteratus Targets a Novel Microsite of the α3β2 Nicotinic Receptor*

D. Craik, R. Lewis, N. Daly, 2010, The Journal of Biological Chemistry.

CD and NMR determination of the solution structure of a peptide corresponding to T4 lysozyme residues 38-51.

D. Craik, J. Wade, M. McLeish, 1995, Biochimica et biophysica acta.

Cyclic analogues of horseshoe crab peptide tachyplesin I with anticancer and cell penetrating properties.

D. Craik, F. Vernen, S. Troeira Henriques, 2019, ACS chemical biology.

Improving the Selectivity of Engineered Protease Inhibitors: Optimizing the P2 Prime Residue Using a Versatile Cyclic Peptide Library.

D. Craik, Jonathan M. Harris, Conan K. Wang, 2015, Journal of medicinal chemistry.

Circular proteins and mechanisms of cyclization

D. Craik, Brendon F. Conlan, M. Anderson, 2010, Biopolymers.

Isolation, sequencing, and structure-activity relationships of cyclotides.

D. Craik, N. Daly, R. Clark, 2010, Journal of natural products.

Engineering the Cyclization Loop of MCoTI-II Generates Targeted Cyclotides that Potently Inhibit Factor XIIa.

D. Craik, T. Durek, Conan K. Wang, 2022, Journal of medicinal chemistry.

An 1H NMR determination of the three‐dimensional structures of mirror‐image forms of a Leu‐5 variant of the trypsin inhibitor from Ecballium elaterium (EETI‐II)

D. Craik, S. Kent, K. Nielsen, 1994, Protein science : a publication of the Protein Society.

Discovery, Structural Determination, and Putative Processing of the Precursor Protein That Produces the Cyclic Trypsin Inhibitor Sunflower Trypsin Inhibitor 1*

D. Craik, J. Mulvenna, Fiona M. Foley, 2005, Journal of Biological Chemistry.

The Absolute Structural Requirement for a Proline in the P3′-position of Bowman-Birk Protease Inhibitors Is Surmounted in the Minimized SFTI-1 Scaffold*

Norelle L Daly, David J Craik, D. Craik, 2006, Journal of Biological Chemistry.

High-affinity Cyclic Peptide Matriptase Inhibitors*

D. Craik, Q. Kaas, Yen‐Hua Huang, 2013, The Journal of Biological Chemistry.

Development of cyclic peptide matriptase inhibitors

D. Craik, Q. Kaas, Yen‐Hua Huang, 2013 .

Plant-based production of an orally active cyclotide for the treatment of multiple sclerosis

D. Craik, P. Harvey, M. Jackson, 2023, Transgenic Research.

The radish defensins RsAFP1 and RsAFP2 act synergistically with caspofungin against Candida albicans biofilms

D. Craik, P. Harvey, J. Vleugels, 2016, Peptides.

The Cyclic Cystine Ladder of Theta‐Defensins as a Stable, Bifunctional Scaffold: A Proof‐of‐Concept Study Using the Integrin‐Binding RGD Motif.

Horst Kessler, Petar Stupar, David J Craik, 2014, Chembiochem : a European journal of chemical biology.

Thermally Activated Domain Wall Movement

D. Craik, M. J. Wood, 1966 .

Slow Magnetization Reversals in Cobalt Films

L. F. Bates, D. Craik, S. Rushton, 1962 .

Rational design and synthesis of an orally bioavailable peptide guided by NMR amide temperature coefficients

David J. Craik, David P. Fairlie, Spiros Liras, 2014, Proceedings of the National Academy of Sciences.

Chemical Synthesis, Proper Folding, Nav Channel Selectivity Profile and Analgesic Properties of the Spider Peptide Phlotoxin 1

Michel De Waard, Didier Boturyn, Dietrich Mebs, 2019, Toxins.

Structure of catalytic domain of Matriptase in complex with Sunflower trypsin inhibitor-1

D. Craik, Liqing Chen, E. Meehan, 2011, BMC Structural Biology.

Solution Structure of the Acetylated and Noncleavable Mitochondrial Targeting Signal of Rat Chaperonin 10 (*)

D. Craik, M. Ryan, P. Høj, 1995, The Journal of Biological Chemistry.

Chemical Synthesis and Structure of the Prokineticin Bv8

D. Craik, I. Vetter, T. Durek, 2010, Chembiochem : a European journal of chemical biology.

Gating modifier toxins isolated from spider venom: Modulation of voltage-gated sodium channels and the role of lipid membranes

D. Craik, J. Tytgat, C. Schroeder, 2018, The Journal of Biological Chemistry.

X-ray diffraction studies of fibrils formed from peptide fragments of transthyretin.

D. Craik, M. Wilce, J. A. Jarvis, 1993, Biochemical and biophysical research communications.

NMR and Drug Discovery

D. Craik, R. Clark, 2003 .

Heparan sulfate regulates IL-21 bioavailability and signal strength that control germinal center B cell selection and differentiation

D. Craik, Yen‐Hua Huang, Conan K. Wang, 2023, Science Immunology.

Naturally Occurring Circular Proteins: Distribution, Biosynthesis and Evolution

D. Craik, L. Cascales, 2011 .

Importance of the Cyclic Cystine Knot Structural Motif for Immunosuppressive Effects of Cyclotides

D. Craik, P. Harvey, C. Gruber, 2021, ACS chemical biology.

Discovery, isolation, and structural characterization of cyclotides from Viola sumatrana Miq

D. Craik, M. Colgrave, L. Y. Chan, 2016, Biopolymers.

Molecular Grafting onto a Stable Framework Yields Novel Cyclic Peptides for the Treatment of Multiple Sclerosis

David J. Craik, D. Craik, Conan K. Wang, 2013, ACS chemical biology.

A systematic approach to document cyclotide distribution in plant species from genomic, transcriptomic, and peptidomic analysis.

D. Craik, Q. Kaas, D. Mondal, 2013, Biopolymers.

Insights into Processing and Cyclization Events Associated with Biosynthesis of the Cyclic Peptide Kalata B1*

D. Craik, M. Colgrave, R. Guarino, 2012, The Journal of Biological Chemistry.

Combined X-ray and NMR Analysis of the Stability of the Cyclotide Cystine Knot Fold That Underpins Its Insecticidal Activity and Potential Use as a Drug Scaffold*

J. Hajdu, D. Craik, N. Tan, 2009, Journal of Biological Chemistry.

Variations in cyclotide expression in viola species.

D. Craik, M. Trabi, L. Bohlin, 2004, Journal of natural products.

Magnetic-domain-wall pinning by regions of weak exchange or anisotropy

D. Craik, E. Hill, 1974 .

Domain wall calculations for SmCo 5

D. Craik, E. Hill, A. Harrison, 1975 .

A measurement of the CKM angle from studies of DK∏ Dalitz plots

D. Craik, 2015 .

The cyclotides and related macrocyclic peptides as scaffolds in drug design.

Masa Cemazar, Norelle L Daly, David J Craik, 2006, Current opinion in drug discovery & development.

Protease SFTI complex

J. Whisstock, D. Craik, T. Durek, 2019 .

Conopeptides as novel options for pain management

D. Craik, N. Daly, 2011 .

Cyclic Peptides as T-Type Calcium Channel Blockers: Characterization and Molecular Mapping of the Binding Site.

D. Craik, J. Tytgat, O. Cheneval, 2021, ACS pharmacology & translational science.

Magnetization Processes in a Polycrystalline Manganese Zinc Ferrite

L. F. Bates, D. Craik, H. Clow, 1958 .

Microstructure and magnetic properties of sintered SmCo5

D. Craik, E. Hill, 1977 .

C-13 and N-15 Nuclear Magnetic-Resonance of Polycyclic Polyamines - a Study of Solution N-H Hydrogen-Bonding and Protonation

G. C. Levy, D. Craik, A. Lombardo, 2002 .

A radish seed antifungal peptide with a high amyloid fibril-forming propensity.

D. Craik, H. Schirra, J. Carver, 2013, Biochimica et biophysica acta.

Domain Configurations on Ferrites

D. Craik, P. M. Griffiths, 1959 .

The effect of the cubic anisotropy on the behaviour of uniaxial garnet films

D. Craik, G. Gavoille, 1977 .

Dynamic Bloch line formation in magnetic garnet films

D. Craik, D. Cottey, 1975 .

The domain structure of magnetoplumbite

L. F. Bates, D. Craik, P. M. Griffiths, 1959, Proceedings of the Royal Society of London. Series A. Mathematical and Physical Sciences.

New techniques for the study of Bitter figures

D. Craik, P. M. Griffiths, 1958 .

Magnetostatic and exchange interactions between particles in permanent magnet materials

D. Craik, R. Lane, 1969 .

PTRF/cavin-1 neutralizes non-caveolar caveolin-1 microdomains in prostate cancer

D. Craik, P. Russell, K. Inder, 2013, Oncogene.

In Vivo Efficacy of Anuran Trypsin Inhibitory Peptides against Staphylococcal Skin Infection and the Impact of Peptide Cyclization

D. Craik, O. Franco, O. N. Silva, 2015, Antimicrobial Agents and Chemotherapy.

Functional Analysis of the α-Defensin Disulfide Array in Mouse Cryptdin-4*

D. Craik, A. Henschen-Edman, A. Ouellette, 2004, Journal of Biological Chemistry.

1H NMR Spectroscopic Studies of the Stability of an Oxazolidine Condensation Product

D. Craik, M. Iskander, G. P. Moloney, 1997 .

A suite of kinetically superior AEP ligases can cyclise an intrinsically disordered protein

D. Craik, Q. Kaas, T. Durek, 2019, Scientific Reports.

Peptide macrocyclization by a bifunctional endoprotease.

D. Craik, C. Nelson, J. Mylne, 2015, Chemistry & biology.

Chemical re-engineering of chlorotoxin improves bioconjugation properties for tumor imaging and targeted therapy.

Norelle L Daly, David J Craik, James M Olson, 2011, Journal of medicinal chemistry.

Inhibitors of β-Amyloid Formation Based on the β-Secretase Cleavage Site

R. Tanzi, D. Craik, D. Fairlie, 2000 .

Synthesis, Racemic X-ray Crystallographic, and Permeability Studies of Bioactive Orbitides from Jatropha Species.

D. Craik, Yen‐Hua Huang, Conan K. Wang, 2018, Journal of natural products.

The cyclic antimicrobial peptide RTD‐1 induces stabilized lipid–peptide domains more efficiently than its open‐chain analogue

D. Craik, M. Trabi, K. Lohner, 2004, FEBS letters.

Evaluation of Efficient Non-reducing Enzymatic and Chemical Ligation Strategies for Complex Disulfide-Rich Peptides.

D. Craik, I. Vetter, C. Schroeder, 2021, Bioconjugate chemistry.

Synthesis of cyclic disulfide-rich peptides.

D. Craik, Muharrem Akcan, 2013, Methods in molecular biology.

A determination of the solution conformation of the nonmammalian tachykinin eledoisin by NMR and CD spectroscopy.

D. Craik, M. McLeish, J. Wilson, 1994, Biochemistry.

Characterization of Tachyplesin Peptides and Their Cyclized Analogues to Improve Antimicrobial and Anticancer Properties

D. Craik, P. Harvey, Yen‐Hua Huang, 2019, International journal of molecular sciences.

Dual-targeting anti-angiogenic cyclic peptides as potential drug leads for cancer therapy

D. Craik, N. Daly, L. Y. Chan, 2016, Scientific Reports.

Optimization of the cyclotide framework to improve cell penetration properties

D. Craik, O. Cheneval, Yen‐Hua Huang, 2015, Front. Pharmacol..

Cyclization of the Antimicrobial Peptide Gomesin with Native Chemical Ligation: Influences on Stability and Bioactivity

D. Craik, N. Waters, Yen‐Hua Huang, 2013, Chembiochem : a European journal of chemical biology.

Multidimensional Nuclear Magnetic Resonance of Biomolecules

D. Craik, M. Scanlon, J. Horne, 2008 .

Conotoxin TVIIA, a novel peptide from the venom of Conus tulipa 2. Three-dimensional solution structure.

D. Craik, P. Alewood, J. Hill, 2000, European journal of biochemistry.

Effects of chirality at Tyr13 on the structure-activity relationships of omega-conotoxins from Conus magus.

D. Craik, R. Lewis, P. Alewood, 1999, Biochemistry.

Discovery and mechanistic studies of cytotoxic cyclotides from the medicinal herb Hybanthus enneaspermus

D. Craik, Q. Kaas, Yen‐Hua Huang, 2020, The Journal of Biological Chemistry.

Isolation and characterization of bioactive cyclotides from Viola labridorica.

D. Craik, G. Zeng, N. Tan, 2010 .

Structure-activity analysis of truncated albumin-binding domains suggests new lead constructs for potential therapeutic delivery

D. Craik, J. Weidmann, Conan K. Wang, 2020, The Journal of Biological Chemistry.

An Ultrapotent and Selective Cyclic Peptide Inhibitor of Human β-Factor XIIa in a Cyclotide Scaffold.

D. Craik, Yen‐Hua Huang, K. Ogata, 2021, Journal of the American Chemical Society.

Tuning the Anti-Angiogenic Effect of the P15 Peptide Using Cyclic Trypsin Inhibitor Scaffolds.

D. Craik, L. Y. Chan, Junqiao Du, 2021, ACS chemical biology.

Synthesis and protein engineering applications of cyclotides

D. Craik, T. Durek, Haiou Qu, 2017 .

The synthesis and structure of an n-terminal dodecanoic acid conjugate of α-conotoxin MII

D. Craik, David John Adams, I. Toth, 2006, Letters in Peptide Science.

Structural characterization of the cyclic cystine ladder motif of θ-defensins.

D. Craik, P. Harvey, K. Rosengren, 2012, Biochemistry.

Structural characterisation of galactoglucomannan secreted by suspension-cultured cells of Nicotiana plumbaginifolia.

A. Bacic, D. Craik, I. Sims, 1997, Carbohydrate research.

Engineering of conotoxins for the treatment of pain.

D. Craik, P. Harvey, Q. Kaas, 2011, Current pharmaceutical design.

Stabilization of α-conotoxin AuIB: influences of disulfide connectivity and backbone cyclization.

D. Craik, N. Daly, S. Gunasekera, 2011, Antioxidants & redox signaling.

Ultra-stable peptide scaffolds for protein engineering-synthesis and folding of the circular cystine knotted cyclotide cycloviolacin O2.

D. Craik, U. Göransson, R. Clark, 2008, Chembiochem : a European journal of chemical biology.

Blockade of Neuronal α7-nAChR by α-Conotoxin ImI Explained by Computational Scanning and Energy Calculations

David J. Craik, Quentin Kaas, Rilei Yu, 2011, PLoS Comput. Biol..

Solution structure of BSTI: a new trypsin inhibitor from skin secretions of Bombina bombina.

D. Craik, K. Rosengren, N. Daly, 2001, Biochemistry.

Structure-activity relationships of omega-conotoxins MVIIA, MVIIC and 14 loop splice hybrids at N and P/Q-type calcium channels.

D. Craik, David John Adams, R. Lewis, 1999, Journal of molecular biology.

esized and post-translationally modi fi ed peptide natural products : overview and recommendations for a universal nomenclature

P. G. Arnison, M. Bibb, M. Fischbach, 2012 .

Cyclisation of Disulfide-Rich Conotoxins in Drug Design Applications

D. Craik, Q. Kaas, Yen‐Hua Huang, 2016 .

Nematicidal Activity of Cyclotides: Toxicity Against Caenorhabditis elegans.

D. Craik, Yen‐Hua Huang, M. Jackson, 2023, Journal of natural products.

Design, synthesis and mechanism of action of novel μ-conotoxin KIIIA analogs for inhibition of the voltage-gated sodium channel Nav1.7.

D. Craik, P. Harvey, Linhong Huang, 2023, The Journal of biological chemistry.

Cyclotides as Tools in Chemical Biology.

Joachim Weidmann, D. Craik, J. Weidmann, 2017, Accounts of chemical research.

Structural Analysis of the Carbohydrate Moiety of Arabinogalactan- Proteins from Stigmas and Styles of Nicotiana alata.

A. Bacic, D. Craik, G. Howlett, 1996 .

1H and 13C NMR studies of aminoglycoside antibiotics

D. Craik, M. Iskander, G. P. Moloney, 1993 .

Cyclic gomesin, a stable redesigned spider peptide able to enter cancer cells.

D. Craik, O. Cheneval, Yen‐Hua Huang, 2020, Biochimica et biophysica acta. Biomembranes.

Truncated Glucagon-like Peptide-1 and Exendin-4 α-Conotoxin pl14a Peptide Chimeras Maintain Potency and α-Helicity and Reveal Interactions Vital for cAMP Signaling in Vitro*

D. Craik, P. Loria, David A. Price, 2016, The Journal of Biological Chemistry.

RESEARCH NOTES: A New Colloid for use with the Bitter Figure Technique

D. Craik, P. M. Griffiths, 1957 .

A Study of Bitter Figures using the Electron Microscope

D. Craik, 1956 .

CyBase: a database of cyclic protein sequence and structure

Jason P. Mulvenna, Conan K. L. Wang, David J. Craik, 2005, Nucleic Acids Res..

Solution structure of the sodium channel antagonist conotoxin GS: a new molecular caliper for probing sodium channel geometry.

D. Craik, P. Alewood, J. Hill, 1997, Structure.

Determination of the Solution Structures of Conantokin-G and Conantokin-T by CD and NMR Spectroscopy*

D. Craik, R. Lewis, P. Alewood, 1997, The Journal of Biological Chemistry.

Phage display-based discovery of cyclic peptides against the broad spectrum bacterial anti-virulence target CsrA.

D. Craik, P. Harvey, T. Durek, 2022, European journal of medicinal chemistry.

Cyclotides as drug design scaffolds.

D. Craik, Junqiao Du, 2017, Current opinion in chemical biology.

Efficient Enzymatic Ligation of Inhibitor Cystine Knot Spider Venom Peptides: Using Sortase A To Form Double-Knottins That Probe Voltage-Gated Sodium Channel NaV1.7.

D. Craik, C. Schroeder, G. King, 2018, Bioconjugate chemistry.

Spider peptide toxin HwTx-IV engineered to bind to lipid membranes has an increased inhibitory potency at human voltage-gated sodium channel hNaV1.7.

D. Craik, O. Cheneval, C. Schroeder, 2017, Biochimica et biophysica acta. Biomembranes.

Solution Structure and Characterization of the LGR8 Receptor Binding Surface of Insulin-like Peptide 3*

D. Craik, J. Wade, K. Rosengren, 2006, Journal of Biological Chemistry.

Chemical synthesis and folding pathways of large cyclic polypeptides: studies of the cystine knot polypeptide kalata B1.

D. Craik, N. Daly, P. Alewood, 1999, Biochemistry.

Biodistribution of the cyclotide MCoTI‐II, a cyclic disulfide‐rich peptide drug scaffold

D. Craik, Conan K. Wang, Sofie Stalmans, 2016, Journal of peptide science : an official publication of the European Peptide Society.

The cyclotides: novel macrocyclic peptides as scaffolds in drug design.

Norelle L Daly, David J Craik, D. Craik, 2002, Current opinion in drug discovery & development.

Determination of the solution structure of neuropeptide K by high-resolution nuclear magnetic resonance spectroscopy.

D. Craik, M. Sadek, J. Horne, 1993, Biochemistry.

133Cs relaxation times in rat tissues.

D. Craik, B. Shehan, R. Wellard, 1995, Journal of magnetic resonance. Series B.

Factors affecting 133Cs chemical shifts in erythrocytes from cesium-fed rats.

D. Craik, B. Shehan, R. Wellard, 1994, Journal of magnetic resonance. Series B.

NMR measurement of 39K detectability and relaxation constants in rat tissue

D. Craik, B. Shehan, R. Wellard, 1993, Magnetic resonance in medicine.

Design of Potent and Selective Cathepsin G Inhibitors Based on the Sunflower Trypsin Inhibitor-1 Scaffold.

D. Craik, Conan K. Wang, S. D. de Veer, 2017, Journal of medicinal chemistry.

Development of novel frog‐skin peptide scaffolds with selectivity towards melanocortin receptor subtypes

D. Craik, V. Hruby, Q. Kaas, 2020 .

Neurotoxic peptides from the venom of the giant Australian stinging tree

D. Craik, D. Andersson, I. Vetter, 2020, Science Advances.

Melanocortin 1 Receptor Agonists Based on a Bivalent, Bicyclic Peptide Framework.

Andrew M. White, A. Plowright, D. Craik, 2021, Journal of medicinal chemistry.

Toward Structure Determination of Disulfide-Rich Peptides Using Chemical Shift-Based Methods.

D. Craik, Conan K. Wang, 2019, The journal of physical chemistry. B.

The N‐terminal pro‐domain of the kalata B1 cyclotide precursor is intrinsically unstructured

D. Craik, J. Wade, N. Daly, 2016, Biopolymers.

Captivity induces a sweeping and sustained genomic response in a starfish

B. Degnan, D. Craik, S. Degnan, 2023, Molecular ecology.

The Cyclic Cystine Ladder in θ-Defensins Is Important for Structure and Stability, but Not Antibacterial Activity*

Norelle L Daly, David J Craik, D. Craik, 2013, The Journal of Biological Chemistry.

Native and Engineered Cyclic Disulfide-Rich Peptides as Drug Leads

D. Craik, T. Durek, Tristan J. Tyler, 2023, Molecules.

Intracellular Targeting of Cyclotides for Therapeutic Applications

D. Craik, N. Lawrence, 2021 .

Structure‐based Drug Design and NMR‐based Screening

D. Craik, R. Clark, 2006 .

Probing the interaction of Hoechst 33258 with an A–T rich oligonucleotide duplex using 1H NMR spectroscopy

D. Craik, M. Searle, K. Embrey, 1991 .

Mutagenesis of bracelet cyclotide hyen D reveals functionally and structurally critical residues for membrane binding and cytotoxicity

D. Craik, Q. Kaas, Yen‐Hua Huang, 2022, The Journal of biological chemistry.

Comparative analysis of cyclotide-producing plant cell suspensions presents opportunities for cyclotide plant molecular farming.

D. Craik, Yen‐Hua Huang, M. Jackson, 2021, Phytochemistry.

Enabling Efficient Folding and High-Resolution Crystallographic Analysis of Bracelet Cyclotides

D. Craik, Yen‐Hua Huang, B. Collins, 2021, Molecules.

Circular permutation of the native enzyme-mediated cyclization position in cyclotides.

D. Craik, Yen‐Hua Huang, K. Harris, 2020, ACS chemical biology.

Pharmacokinetic characterization of kalata B1 and related therapeutics built on the cyclotide scaffold.

D. Craik, Yen‐Hua Huang, Thao T. Le, 2019, International journal of pharmaceutics.

Cyclotides from Brazilian Palicourea sessilis and Their Effects on Human Lymphocytes

D. Craik, V. Bolzani, C. Gruber, 2021, Journal of natural products.

Cyclic Peptides Arising by Evolutionary Parallelism via Asparaginyl-Endopeptidase–Mediated Biosynthesis[C][W]

Timothy L Bailey, Norelle L Daly, David J Craik, 2012, Plant Cell.

Effect of magnesium depletion and potassium and chlorothiazide on intracellular pH in the rat, studied by 31P NMR

D. Craik, R. Wellard, M. Kneen, 1989 .

The interactions of the N-terminal fusogenic peptide of HIV-1 gp41 with neutral phospholipids

D. Craik, F. Separovic, K. Nielsen, 1999, European Biophysics Journal.

FUNCTIONAL GROUP CONTRIBUTIONS TO DRUG-RECEPTOR INTERACTIONS

David J. Craik, Peter R. Andrews, P. Andrews, 1985 .

Early development of Monoplex pilearis and Monoplex parthenopeus (Gastropoda: Cymatiidae): biology and morphology

D. Craik, Q. Kaas, C. Schroeder, 2020, Organisms Diversity & Evolution.

Chemical synthesis, 3D structure, and ASIC binding site of the toxin mambalgin-2.

D. Craik, C. Schroeder, T. Durek, 2014, Angewandte Chemie.

The Cell Wall Galactan of Catenella nipae Zanardini from Southern Australia

A. Bacic, D. Craik, G. Kraft, 1993 .

Kappa-/beta-carrageenans from Australian red algae of the Acrotylaceae (Gigartinales, Rhodophyta)

A. Bacic, D. Craik, A. Chiovitti, 2008 .

The three-dimensional solution structure of NaD1, a new floral defensin from Nicotiana alata and its application to a homology model of the crop defense protein alfAFP.

D. Craik, H. Schirra, F. T. Lay, 2003, Journal of molecular biology.

Domain Structures and Coercivity of Alcomax III

L. F. Bates, D. Craik, E. Isaac, 1962 .

How can we improve peptide drug discovery? Learning from the past

D. Craik, M. Kan, 2021, Expert opinion on drug discovery.

Production of a structurally validated cyclotide in rice suspension cells is enabled by a supporting biosynthetic enzyme

D. Craik, P. Harvey, M. Jackson, 2020, Planta.

Anchor Residues Guide Form and Function in Grafted Peptides.

D. Craik, Conan K. Wang, Huawu Yin, 2019, Angewandte Chemie.

Anchor Residues Guide Form and Function in Grafted Peptides

D. Craik, Conan K. Wang, Huawu Yin, 2019, Angewandte Chemie.

Targeted Delivery of Cyclotides via Conjugation to a Nanobody.

D. Craik, H. Ploegh, O. Cheneval, 2018, ACS chemical biology.

Using the MCoTI-II Cyclotide Scaffold To Design a Stable Cyclic Peptide Antagonist of SET, a Protein Overexpressed in Human Cancer.

M. Sweet, D. Craik, O. Cheneval, 2016, Biochemistry.

The role of disulfide bonds in structure and activity of chlorotoxin.

D. Craik, Conan K. Wang, L. Y. Chan, 2014, Future medicinal chemistry.

Translational diffusion of cyclic peptides measured using pulsed-field gradient NMR.

A. Mathiowetz, D. Craik, David A. Price, 2014, The journal of physical chemistry. B.

Structure-activity relationships of alpha-conotoxins targeting neuronal nicotinic acetylcholine receptors.

David J. Craik, Norelle L. Daly, D. Craik, 2004, European journal of biochemistry.

Design of a Highly Stable Disulfide-Deleted Mutant of Analgesic Cyclic alpha-Conotoxin Vc1.1

David J. Craik, Quentin Kaas, Xinying Jia, 2016 .

Key challenges for the creation and maintenance of specialist protein resources

Bernard Henrissat, Ramanathan Sowdhamini, Gert Vriend, 2015, Proteins.

Application and Structural Analysis of Triazole-Bridged Disulfide Mimetics in Cyclic Peptides.

Andrew G. White, D. Craik, P. Harvey, 2020, Angewandte Chemie.

Binding loop substitutions in the cyclic peptide SFTI-1 generate potent and selective chymase inhibitors.

D. Craik, S. D. de Veer, Joakim E. Swedberg, 2019, Journal of medicinal chemistry.

Iterative Optimization of the Cyclic Peptide SFTI-1 Yields Potent Inhibitors of Neutrophil Proteinase 3.

D. Craik, S. D. de Veer, Joakim E. Swedberg, 2019, ACS medicinal chemistry letters.

Amino Acid Scanning at P5' within the Bowman-Birk Inhibitory Loop Reveals Specificity Trends for Diverse Serine Proteases.

D. Craik, Jonathan M. Harris, Xingchen Chen, 2019, Journal of medicinal chemistry.

Engineering potent mesotrypsin inhibitors based on the plant-derived cyclic peptide, sunflower trypsin inhibitor-1.

D. Craik, C. Schroeder, S. D. de Veer, 2018, European journal of medicinal chemistry.

Structure of α-conotoxin BuIA: influences of disulfide connectivity on structural dynamics

D. Craik, David John Adams, N. Daly, 2007, BMC Structural Biology.

Scalable and Efficient In Planta Biosynthesis of Sunflower Trypsin Inhibitor-1 (SFTI) Peptide Therapeutics.

D. Craik, M. Jackson, Thomas N. G. Handley, 2022, Methods in molecular biology.

Natural structural diversity within a conserved cyclic peptide scaffold

D. A. Armstrong, D. Craik, K. Rosengren, 2016, Amino Acids.

scaffolds Engineering pro-angiogenic peptides using stable disulfide-rich cyclic

Julie H. Campbell, D. Craik, S. Henriques, 2012 .

A bifunctional asparaginyl endopeptidase efficiently catalyzes both cleavage and cyclization of cyclic trypsin inhibitors

D. Craik, Q. Kaas, T. Durek, 2020, Nature Communications.

A suite of kinetically superior AEP ligases can cyclise an intrinsically disordered protein

D. Craik, Q. Kaas, T. Durek, 2019, Scientific Reports.

Rapid and Scalable Plant-Based Production of a Potent Plasmin Inhibitor Peptide

D. Craik, T. Durek, K. Harris, 2019, Front. Plant Sci..

Molecular basis for the production of cyclic peptides by plant asparaginyl endopeptidases

D. Craik, M. Anderson, Thomas M A Shafee, 2018, Nature Communications.

Discovery and applications of disulfide-rich cyclic peptides.

D. Craik, Anjaneya S. Ravipati, T. Mahatmanto, 2012, Current topics in medicinal chemistry.

The Prototypic Cyclotide Kalata B1 Has a Unique Mechanism of Entering Cells.

D. Craik, Yen‐Hua Huang, Stephanie Chaousis, 2015, Chemistry & biology.

The three‐dimensional structure of the analgesic α‐conotoxin, RgIA

D. Craik, David John Adams, N. Daly, 2008, FEBS letters.

Retrocyclin-2: structural analysis of a potent anti-HIV theta-defensin.

Wei Wang, Norelle L Daly, David J Craik, 2007, Biochemistry.

Structural and functional characterization of the conserved salt bridge in mammalian paneth cell alpha-defensins: solution structures of mouse CRYPTDIN-4 and (E15D)-CRYPTDIN-4.

H. Vogel, D. Craik, A. Ouellette, 2006, The Journal of biological chemistry.

NMR of conotoxins: structural features and an analysis of chemical shifts of post‐translationally modified amino acids

D. Craik, U. Marx, N. Daly, 2006, Magnetic resonance in chemistry : MRC.

Structure of Petunia hybrida defensin 1, a novel plant defensin with five disulfide bonds.

D. Craik, H. Schirra, F. T. Lay, 2003, Biochemistry.

Synthesis, NMR Studies and Conformational Analysis of Oxazolidine Derivatives of the β-Adrenoreceptor Antagonists Metoprolol, Atenolol, and Timolol.

D. Craik, T. Nero, M. Iskander, 1998 .

Synthesis of cyclic penta- and hexapeptides: A general synthetic strategy on DAS resin

D. Craik, D. Scanlon, Paul B. Jones, 1994, Journal of protein chemistry.

A bifunctional asparaginyl endopeptidase efficiently catalyzes both cleavage and cyclization of cyclic trypsin inhibitors

D. Craik, Q. Kaas, T. Durek, 2020, Nature Communications.

Insecticidal diversity of butterfly pea (Clitoria ternatea) accessions

D. Craik, Yen‐Hua Huang, M. Jackson, 2020 .

Stoichiometry dependent inhibition of rat &agr;3&bgr;4 nicotinic acetylcholine receptor by the ribbon isomer of &agr;‐conotoxin AuIB

D. Craik, David John Adams, Q. Kaas, 2018, Biochemical pharmacology.

Stoichiometry dependent inhibition of rat α3β4 nicotinic acetylcholine receptor by the ribbon isomer of α-conotoxin AuIB

D. Craik, David John Adams, Q. Kaas, 2018 .

A New Level of Conotoxin Diversity, a Non-native Disulfide Bond Connectivity in α-Conotoxin AuIB Reduces Structural Definition but Increases Biological Activity*

D. Craik, David John Adams, R. Hogg, 2002, The Journal of Biological Chemistry.

Conotoxins and their potential pharmaceutical applications

David J. Craik, Paul F. Alewood, D. Craik, 1999 .

A Computationally Designed Peptide Derived from Escherichia coli as a Potential Drug Template for Antibacterial and Antibiofilm Therapies.

Karen G. N. Oshiro, T. Lu, D. Craik, 2018, ACS infectious diseases.

Designing antimicrobial peptides using deep learning and molecular dynamic simulations

D. Craik, P. Harvey, M. Mobli, 2023, Briefings Bioinform..

Functional analysis of the alpha-defensin disulfide array in mouse cryptdin-4.

D. Craik, A. Henschen-Edman, A. Ouellette, 2004, The Journal of biological chemistry.

Domain Patterns on a Single Crystal of Manganese Ferrite

L. F. Bates, D. Craik, P. M. Griffiths, 1958 .

Anisatin: a Crystallographic, N.M.R. and Theoretical Conformation Study

J. Gulbis, P. Andrews, D. Craik, 1988 .

Unlocking the Potential of the Antimicrobial Peptide Gomesin: From Discovery and Structure–Activity Relationships to Therapeutic Applications

D. Craik, S. Henriques, L. Y. Chan, 2023, International journal of molecular sciences.

Redesigned Spider Peptide with Improved Antimicrobial and Anticancer Properties.

D. Craik, O. Cheneval, Yen‐Hua Huang, 2017, ACS chemical biology.

Structural and functional characterization of chimeric cyclotides from the Möbius and trypsin inhibitor subfamilies

D. Craik, C. Schroeder, Yen‐Hua Huang, 2017, Biopolymers.

Enhanced Activity against Multi-drug Resistant Bacteria through Coapplication of an Analogue of Tachyplesin I and an Inhibitor of the QseC/B Signaling Pathway.

D. Craik, P. Harvey, Q. Kaas, 2020, Journal of medicinal chemistry.

Effects of backbone cyclization on the pharmacokinetics and drug efficiency of the orally active analgesic conotoxin cVc1.1

David M. Shackleford, D. Craik, T. Durek, 2021 .

NMR in peptide drug development.

D. Craik, Jan-Christoph Westermann, 2008, Methods in molecular biology.

STRUCTURE AND ACTIVITY OF α -CONOTOXIN PeIA AT NICOTINIC ACETYLCHOLINE RECEPTOR SUBTYPES AND GABA B RECEPTOR-COUPLED N-TYPE CALCIUM CHANNELS

D. Craik, David John Adams, N. Daly, 2010 .

Qualitative analysis of the stability of the oxazine ring of various benzoxazine and pyridooxazine derivatives with proton nuclear magnetic resonance spectroscopy.

D. Craik, M. Iskander, G. P. Moloney, 1992, Journal of pharmaceutical sciences.

Exploring experimental and computational markers of cyclic peptides: Charting islands of permeability.

Spiros Liras, D. Craik, David A. Price, 2015, European journal of medicinal chemistry.

The structure of microcin J25 is a threaded sidechain-to-backbone ring structure and not a head-to-tail cyclized backbone

D. Craik, K. Rosengren, N. Daly, 2003 .

Secondary structure of the third extracellular loop responsible for ligand selectivity of a mammalian gonadotropin-releasing hormone receptor.

D. Craik, H. Klump, W. Kiefer, 2002, Journal of medicinal chemistry.

Solution structure of chi-conopeptide MrIA, a modulator of the human norepinephrine transporter.

D. Craik, K. Nilsson, R. Lewis, 2005, Biopolymers.

Evaluation of the in Vivo Aphrodisiac Activity of a Cyclotide Extract from Hybanthus enneaspermus.

D. Craik, Yen‐Hua Huang, Abhishek Bajpai, 2020, Journal of natural products.

A conformational study by proton NMR of a cyclic pentapeptide antagonist of endothelin

D. Craik, M. Coles, D. Scanlon, 1993 .

Peptide rope tricks

D. Craik, K. Rosengren, 2010 .

Three-dimensional solution structure of alpha-conotoxin MII by NMR spectroscopy: effects of solution environment on helicity.

D. Craik, P. Alewood, L. Miranda, 1998, Biochemistry.

Anticancer and Toxic Properties of Cyclotides are Dependent on Phosphatidylethanolamine Phospholipid Targeting

D. Craik, Yen‐Hua Huang, Stephanie Chaousis, 2014, Chembiochem : a European journal of chemical biology.

Peptide-Membrane Interactions Affect the Inhibitory Potency and Selectivity of Spider Toxins ProTx-II and GpTx-1.

D. Craik, O. Cheneval, C. Schroeder, 2018, ACS chemical biology.

Effects of arginine 10 to lysine substitution on ω‐conotoxin CVIE and CVIF block of Cav2.2 channels

D. Craik, David John Adams, N. Daly, 2014, British journal of pharmacology.

Mapping of voltage sensor positions in resting and inactivated mammalian sodium channels by LRET

F. Bezanilla, D. Craik, T. Durek, 2017, Proceedings of the National Academy of Sciences.

The circular bacteriocin enterocin NKR-5-3B has an improved stability profile over nisin

D. Craik, Yen‐Hua Huang, S. Henriques, 2023, Peptides.

Calcium-Mediated Allostery of the EGF Fold.

D. Craik, J. Weidmann, P. Harvey, 2018, ACS Chemical Biology.

Tyrosine-rich Conopeptides Affect Voltage-gated K+ Channels*

D. Craik, N. Daly, B. Olivera, 2008, Journal of Biological Chemistry.

ConoServer, a database for conopeptide sequences and structures

Conan K. L. Wang, David J. Craik, Quentin Kaas, 2008, Bioinform..

Membrane-binding properties of gating modifier and pore-blocking toxins: Membrane interaction is not a prerequisite for modification of channel gating.

A. Mark, D. Craik, Jennifer J. Smith, 2016, Biochimica et biophysica acta.

Synthesis and Conformational Analysis of the Slime-Mold Acrasin Glorin

D. Craik, I. Nicholls, P. Alewood, 1989 .

Magnetization changes induced by stress in a constant applied field

D. Craik, D J Craik, M J Wood, 1970 .

Exploring the therapeutic potential of an antinociceptive and anti-inflammatory peptide from wasp venom

D. Craik, I. Vetter, J. T. Goulart, 2023, Scientific reports.

Antimicrobial and Anticancer Properties of Synthetic Peptides Derived from the Wasp Parachartergus fraternus

D. Craik, P. Harvey, L. Y. Chan, 2020, ChemBioChem.

Creating a specialist protein resource network: a meeting report for the protein bioinformatics and community resources retreat

Neil D. Rawlings, Robert D. Finn, Alex Bateman, 2015, Database J. Biol. Databases Curation.

Creating a specialist protein resource network

Neil D. Rawlings, Alex Bateman, Bernard Henrissat, 2015 .

Discovery and Characterization of Cyclotides from Rinorea Species.

D. Craik, P. Harvey, M. Colgrave, 2018, Journal of natural products.

Cyclizing Disulfide-Rich Peptides Using Sortase A.

D. Craik, C. Schroeder, A. Agwa, 2019, Methods in molecular biology.

Prediction and characterization of cyclic proteins from sequences in three domains of life.

Lukasz Kurgan, Marcin J Mizianty, Quentin Kaas, 2014, Biochimica et biophysica acta.

The α-defensin salt-bridge induces backbone stability to facilitate folding and confer proteolytic resistance

D. Craik, A. Ouellette, K. Rosengren, 2012, Amino Acids.

High level of aspartic acid‐bond isomerization during the synthesis of an N‐linked τ glycopeptide

D. Craik, R. Hoffmann, L. Otvos Jr, 1999, Journal of peptide science : an official publication of the European Peptide Society.

Factors affecting 39K NMR detectability in rat tissue

D. Craik, B. Shehan, R. Wellard, 1991, Magnetic resonance in medicine.

The role of conserved Glu residue on cyclotide stability and activity: a structural and functional study of kalata B12, a naturally occurring Glu to Asp mutant.

D. Craik, P. Harvey, K. Rosengren, 2011, Biochemistry.

The evaluation of magnetic bubble domain specimens

D. Craik, P. Cooper, G. Myers, 1973 .

Applications of NMR in Drug Design: Structure-Activity Relationships in Disulfide-Rich Peptides

D. Craik, 1999, Protein & Peptide Letters.

Oxidative folding of the cystine knot motif in cyclotide proteins.

D. Craik, N. Daly, 2005, Protein and peptide letters.

Identification of initiation sites for T4 lysozyme folding using CD and NMR spectroscopy of peptide fragments.

D. Craik, J. Wade, M. McLeish, 2000, Biochemistry.

ADVANCES IN BOTANICAL RESEARCH Plant Cyclotides

D. Craik, 2015 .

Development of Antiplasmodial Peptide-Drug Conjugates Using a Human Protein-Derived Cell-Penetrating Peptide with Selectivity for Infected Cells.

Andrew M. White, D. Craik, L. Malins, 2023, Bioconjugate chemistry.

Structures of μO-conotoxins from Conus marmoreus

D. Craik, David John Adams, R. Lewis, 2004, Journal of Biological Chemistry.

Yeast-based bioproduction of disulfide-rich peptides and their cyclization via asparaginyl endopeptidases

D. Craik, T. Durek, L. Lua, 2021, Nature Protocols.

The three-dimensional solution structure of mini-M conotoxin BtIIIA reveals a disconnection between disulfide connectivity and peptide fold.

D. Craik, Muharrem Akcan, Ying-Juan Cao, 2013, Bioorganic & medicinal chemistry.

Efficient Enzymatic Cyclization of Disulfide‐Rich Peptides by Using Peptide Ligases

Hein J. Wijma, D. Craik, D. Janssen, 2019, Chembiochem : a European journal of chemical biology.

Structure and folding of potato type II proteinase inhibitors: circular permutation and intramolecular domain swapping.

Horst Joachim Schirra, David J Craik, D. Craik, 2005, Protein and peptide letters.

Structures of a series of 6-kDa trypsin inhibitors isolated from the stigma of Nicotiana alata.

D. Craik, M. Anderson, R. Heath, 1995, Biochemistry.

Discovery and applications of circular cystine knotted peptides

D. Craik, T. Ganz, E. Nemeth, 2012 .

Structure-Activity Relationships of Alanine Scan Mutants αO-Conotoxins GeXIVA[1,2] and GeXIVA[1,4].

D. Craik, P. Harvey, Q. Kaas, 2023, Journal of medicinal chemistry.

Chemical modification of conotoxins to improve stability and activity.

David J Craik, David J Adams, D. Craik, 2007, ACS chemical biology.

marine drugs

D. Craik, Q. Kaas, Linh T. T. Nguyen, 2022 .

Effects of linker sequence modifications on the structure, stability, and biological activity of a cyclic α‐conotoxin

D. Craik, David John Adams, R. Clark, 2016, Biopolymers.

Conotoxins: natural product drug leads.

D. Craik, Reena Halai, 2009, Natural product reports.

Engineering Cyclic Peptide Toxins

D. Craik, R. Clark, 2012 .

Discovery and Characterization of Cyclic and Acyclic Trypsin Inhibitors from Momordica dioica.

D. Craik, L. Y. Chan, Aaron G. Poth, 2019, Journal of natural products.

Despite a conserved cystine knot motif, different cyclotides have different membrane binding modes.

D. Craik, Q. Kaas, Conan K. Wang, 2009, Biophysical journal.

Orientation and Location of the Cyclotide Kalata B1 in Lipid Bilayers Revealed by Solid-State NMR.

D. Craik, O. Cheneval, R. Heinzmann, 2017, Biophysical journal.

CHAPTER 11:Engineering Venom Peptides to Improve Their Stability and Bioavailability

D. Craik, Muharrem Akcan, 2015 .

Apparatus for quasi-static and dynamic measurements on magnetic films

D. Craik, M. J. Wood, 1965 .

Uniaxial films with square hard-direction loops

D. Craik, M. J. Wood, 1966 .

SOLUTION STRUCTURE OF MCOTI-II, A MACROCYCLIC TRYPSIN INHIBITOR

D. Craik, N. Daly, M. E. Felizmenio-Quimio, 2001 .

Structural Analysis of the Complex of Human Transthyretin with 3′,5′-Dichlorophenylanthranilic Acid at 1.5 Å Resolution

V. Cody, D. Craik, J. Holien, 2022, Molecules.

Thyroid hormone uptake by hepatocytes: structure-activity relationships of phenylanthranilic acids with inhibitory activity.

D. Craik, D. Chalmers, D. Topliss, 1993, Journal of medicinal chemistry.

Thematic Minireview Series on Circular Proteins

David J Craik, N. Allewell, D. Craik, 2012, The Journal of Biological Chemistry.

Solution Dynamics of Imipramine and Amitriptyline in Phospholipid Vesicles as Studied by 1H and 13C NMR

D. Craik, M. Casarotto, 1993 .

13C and 1H NMR studies of nitrogen inversion and molecular flexibility in the tricyclic antidepressant drug trimipramine maleate

D. Craik, S. Munro, Jennifer C. Wilson, 1995 .

Carbon-13 and proton NMR studies of the interaction of tricyclic antidepressant drugs with dodecyldimethylammonium chloride micelles

D. Craik, M. Casarotto, 1992 .

Synthesis and Structural Analysis of the N-Terminal Domain of the Thyroid Hormone-Binding Protein Transthyretin

D. Craik, J. Wilce, N. Daly, 2002, Clinical chemistry and laboratory medicine.

NMR in drug design

D. Craik, 1996 .

Evolutionary Origins of a Bioactive Peptide Buried within Preproalbumin[C][W]

D. Craik, K. Rosengren, D. Ortiz-Barrientos, 2014, Plant Cell.

Design, Synthesis, Structural and Functional Characterization of Novel Melanocortin Agonists Based on the Cyclotide Kalata B1*

D. Craik, T. Andresen, B. Wulff, 2012, The Journal of Biological Chemistry.

Plant-Derived Decapeptide OSIP108 Interferes with Candida albicans Biofilm Formation without Affecting Cell Viability

D. Craik, M. Fröhlich, T. Coenye, 2014, Antimicrobial Agents and Chemotherapy.

Racemic and quasi-racemic X-ray structures of cyclic disulfide-rich peptide drug scaffolds.

D. Craik, Conan K. Wang, Paola G Ojeda, 2014, Angewandte Chemie.

Two Blast-independent tools, CyPerl and CyExcel, for harvesting hundreds of novel cyclotides and analogues from plant genomes and protein databases

D. Craik, Zebo Huang, A. Baker, 2014, Planta.

Structural Insights into the Role of the Cyclic Backbone in a Squash Trypsin Inhibitor*

D. Craik, K. Rosengren, N. Daly, 2013, The Journal of Biological Chemistry.

The self-association of the cyclotide kalata B2 in solution is guided by hydrophobic interactions.

D. Craik, P. Harvey, K. Rosengren, 2013, Biopolymers.

Cyclotides Associate with Leaf Vasculature and Are the Products of a Novel Precursor in Petunia (Solanaceae)*

D. Craik, M. Colgrave, J. Mylne, 2012, The Journal of Biological Chemistry.

Cyclization of conotoxins to improve their biopharmaceutical properties.

D. Craik, Q. Kaas, N. Daly, 2012, Toxicon : official journal of the International Society on Toxinology.

Improving on nature: making a cyclic heptapeptide orally bioavailable.

D. Craik, S. Liras, D. Fairlie, 2014, Angewandte Chemie.

NMR of plant proteins.

D. Craik, Q. Kaas, 2013, Progress in nuclear magnetic resonance spectroscopy.

Chemical re-engineering of chlorotoxin improves bioconjugation properties for tumor imaging and targeted therapy.

J. Olson, D. Craik, N. Daly, 2011, Journal of medicinal chemistry.

Identification of a beta-turn in the tertiary structure of a peptide fragment of the Alzheimer amyloid protein.

D. Craik, K. Beyreuther, C. Masters, 1990, Biochemistry international.

The Cyclic Cystine Ladder in (cid:1) -Defensins Is Important for Structure and Stability, but Not Antibacterial Activity *

D. Craik, K. Rosengren, S. Henriques, 2020 .

Carbon-13 and proton NMR studies of the interaction of tricyclic antidepressant drugs with micellar aggregates

D. Craik, M. Casarotto, 1991 .

Naturally occurring circular proteins: distribution, biosynthesis and evolution.

D. Craik, L. Cascales, 2010, Organic & biomolecular chemistry.

The conformation of porcine-brain natriuretic peptide by two-dimensional NMR spectroscopy.

D. Craik, J. Wade, S. Munro, 1991, European journal of biochemistry.

Chemical synthesis and structure elucidation of bovine κ-casein (1–44)☆

D. Craik, N. Daly, P. Alewood, 2006 .

Structure and metal binding studies of the second copper binding domain of the Menkes ATPase.

Christopher E. Jones, D. Craik, P. Cobine, 2003, Journal of structural biology.

Chemical synthesis, characterization and activity of RK‐1, a novel α‐defensin‐related peptide

D. Craik, J. Wade, S. Dashper, 2000, Journal of peptide science : an official publication of the European Peptide Society.

Spider peptide toxin HwTx-IV engineered to bind to lipid membranes has an increased inhibitory potency at human voltage-gated sodium channel hNaV1.7.

D. Craik, O. Cheneval, C. Schroeder, 2017, Biochimica et biophysica acta. Biomembranes.

The measurement of magnetization using Hall probes

D. Craik, 1968 .

The role of disulfide bonds in structure and activity of chlorotoxin.

D. Craik, Conan K. Wang, L. Y. Chan, 2014, Future medicinal chemistry.

Critical size of magnetic particles with high uniaxial anisotropy

D. Craik, D. Mcintyre, 1967, Proceedings of the Royal Society of London. Series A. Mathematical and Physical Sciences.

Conformation of a peptide corresponding to T4 lysozyme residues 59-81 by NMR and CD spectroscopy.

D. Craik, M. McLeish, K. Nielsen, 1994, Biochemistry.

Peptide macrocyclization by a bifunctional endoprotease.

D. Craik, C. Nelson, J. Mylne, 2015, Chemistry & biology.

Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature.

M. Bibb, B. Shen, M. Fischbach, 2013, Natural product reports.

Characterization of a novel α-conotoxin TxID from Conus textile that potently blocks rat α3β4 nicotinic acetylcholine receptors.

D. Craik, P. Harvey, Sean B. Christensen, 2013, Journal of medicinal chemistry.

Cyclization of pyrrhocoricin retains structural elements crucial for the antimicrobial activity of the native peptide

D. Craik, L. Otvos, K. Rosengren, 2004, Biopolymers.

Graphics-Aided NMR

Robert T. C. Brownlee, David J. Craik, D. Craik, 2010 .

Scanning mutagenesis identifies residues that improve the long-term stability and insecticidal activity of cyclotide kalata B1

D. Craik, Q. Kaas, Conan K. Wang, 2024, The Journal of biological chemistry.

The pearl jubilee of microcin J25: thirty years of research on an exceptional lasso peptide.

D. Craik, K. Beis, A. J. Link, 2024, Natural product reports.

Testing of Insulin Hexamer-Stabilizing Ligands Using Theoretical Binding, Microcalorimetry, and Nuclear Magnetic Resonance (NMR) Line Broadening Techniques

D. Craik, S. Lindenbaum, S. E. Mcgraw, 1990, Pharmaceutical Research.

The magnetic domain structures of small crystals

D. Craik, 1970 .

Magneto-optic diffraction and magnetization of thin films

D. Craik, S. Kern, 1976 .

Simple approximations to the magnetostatic energy of domains in uniaxial platelets

D. Craik, P. Cooper, 1973 .

Short Cationic Peptide Derived from Archaea with Dual Antibacterial Properties and Anti-Infective Potential.

Suzana M. Ribeiro, Karen G. N. Oshiro, T. Lu, 2019, ACS infectious diseases.

Seasonal tissue-specific gene expression in wild crown-of-thorns starfish reveals reproductive and stress-related transcriptional systems

B. Degnan, D. Craik, S. Degnan, 2024, PLoS biology.

Seasonal tissue-specific gene expression reveals reproductive and stress-related transcriptional systems in wild crown-of-thorns starfish

B. Degnan, D. Craik, S. Degnan, 2023, bioRxiv.

Engineered EGF-A Peptides with Improved Affinity for Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9).

D. Craik, Conan K. Wang, C. Lammi, 2021, ACS chemical biology.

Cis-trans isomerization of the proline residue in insulin studied by 13C NMR spectroscopy.

P. Andrews, D. Craik, J. Hall, 1988, Drug design and delivery.

The folding of disulfide-rich proteins.

D. Craik, 2011, Antioxidants & redox signaling.

Proximity Labelling Confirms the Involvement of Papain-Like Cysteine Proteases and Chaperones in Cyclotide Biosynthesis

D. Craik, E. Gilding, Fabian B. H. Rehm, 2024, Plant Molecular Biology Reporter.

Translational diffusion of cyclic peptides measured using pulsed-field gradient NMR.

A. Mathiowetz, D. Craik, P. Harvey, 2014, The journal of physical chemistry. B.

A Novel Plant Protein-disulfide Isomerase Involved in the Oxidative Folding of Cystine Knot Defense Proteins*

D. Craik, T. Horibe, R. Clark, 2007, Journal of Biological Chemistry.

Effects of arginine 10 to lysine substitution on ω‐conotoxin CVIE and CVIF block of Cav2.2 channels

D. Craik, David John Adams, N. Daly, 2014, British journal of pharmacology.

RESEARCH PAPER Effects of arginine 10 to lysine substitution on ω -conotoxin CVIE and CVIF block of Ca v 2.2 channels

D. Craik, G. Berecki, P. Alewood, 2014 .