H. Santos

发表

Regulation of glycolysis in Lactococcus lactis: an unfinished systems biological case study.

E. Voit, J. Almeida, S. Marino, 2006, Systems biology.

Is the glycolytic flux in Lactococcus lactis primarily controlled by the redox charge? Kinetics of NAD(+) and NADH pools determined in vivo by 13C NMR.

A. Neves, H. Santos, Rita Ventura, 2002, The Journal of biological chemistry.

In vivo nuclear magnetic resonance studies of glycolytic kinetics in Lactococcus lactis.

M. Kleerebezem, W. D. de Vos, J. Almeida, 1999, Biotechnology and bioengineering.

Glucose fermentation to acetate and alanine in resting cell suspensions of Pyrococcus furiosus: Proposal of a novel glycolytic pathway based on 13C labelling data and enzyme activities

H. Santos, T. Schäfer, K. Xavier, 1994 .

Salt adaptation in Acinetobacter baylyi: identification and characterization of a secondary glycine betaine transporter

H. Santos, V. Berardinis, V. Müller, 2011, Archives of Microbiology.

Organic solutes in hyperthermophilic archaea

R. Huber, H. Santos, K. Stetter, 1997, Applied and environmental microbiology.

Metabolic and Transcriptional Analysis of Acid Stress in Lactococcus lactis, with a Focus on the Kinetics of Lactic Acid Pools

Eberhard O. Voit, Oscar P. Kuipers, Ana Rute Neves, 2013, PloS one.

Effect of pyruvate kinase overproduction on glucose metabolism of Lactococcus lactis.

Ana Rute Neves, Helena Santos, A. Neves, 2004, Microbiology.

Overview on sugar metabolism and its control in Lactococcus lactis - the input from in vivo NMR.

Jan Kok, Ana Rute Neves, Oscar P Kuipers, 2005, FEMS microbiology reviews.

Protein stabilization by compatible solutes. Effect of diglycerol phosphate on the dynamics of Desulfovibrio gigas rubredoxin studied by NMR.

H. Santos, Rita Ventura, C. Maycock, 2003, European journal of biochemistry.

Natural sweetening of food products by engineering Lactococcus lactis for glucose production.

A. Neves, H. Santos, O. Kuipers, 2006, Metabolic engineering.

Metabolism of lactic acid bacteria studied by nuclear magnetic resonance

Ana Rute Neves, Helena Santos, A. Neves, 2004, Antonie van Leeuwenhoek.

Metabolism of lactic acid bacteria studied by nuclear magnetic resonance.

Ana Rute Neves, Helena Santos, A. Neves, 2002 .

The intricate side of systems biology.

Ana Rute Neves, Helena Santos, E. Voit, 2006, Proceedings of the National Academy of Sciences of the United States of America.

Crystallization and preliminary X-ray characterization of cytochrome c" from the obligate methylotroph Methylophilus methylotrophus.

M. A. Carrondo, H. Santos, L. Sieker, 2003, Acta Crystallographica Section D: Biological Crystallography.

From physiology to systems metabolic engineering for the production of biochemicals by lactic acid bacteria.

Susana Vinga, Ana Rute Neves, Helena Santos, 2013, Biotechnology advances.

Metabolic characterization of Lactococcus lactis deficient in lactate dehydrogenase using in vivo 13C-NMR.

J S Almeida, J. Almeida, A. Neves, 2000, European journal of biochemistry.

A highly thermostable trehalase from the thermophilic bacterium Rhodothermus marinus

H. Santos, C. Jorge, Maria-Manuel Sampaio, 2006, Extremophiles.

Specialized Roles of the Two Pathways for the Synthesis of Mannosylglycerate in Osmoadaptation and Thermoadaptation of Rhodothermus marinus*

H. Santos, Nuno Empadinhas, M. Costa, 2004, Journal of Biological Chemistry.

The urgent need for microbiology literacy in society.

A. Danchin, V. de Lorenzo, W. Verstraete, 2019, Environmental microbiology.

Characterization of the Biosynthetic Pathway of Glucosylglycerate in the Archaeon Methanococcoides burtonii

H. Santos, Nuno Empadinhas, M. D. da Costa, 2006, Journal of bacteriology.

A Unique β-1,2-Mannosyltransferase of Thermotoga maritima That Uses Di-myo-Inositol Phosphate as the Mannosyl Acceptor

H. Santos, P. Lamosa, N. Borges, 2009, Journal of bacteriology.

Accumulation of Mannosylglycerate and Di-myo-Inositol-Phosphate by Pyrococcus furiosus in Response to Salinity and Temperature

H. Santos, L. O. Martins, 1995, Applied and environmental microbiology.

Stabilization of Enzymes against Thermal Stress and Freeze-Drying by Mannosylglycerate

J. Lebbink, W. D. de Vos, H. Santos, 1997, Applied and Environmental Microbiology.

Comparative study of the thermostabilizing properties of mannosylglycerate and other compatible solutes on model enzymes

H. Santos, A. Ramos, R. Sharp, 2002, Extremophiles.

The Physiological Role, Biosynthesis, and Mode of Action of Compatible Solutes from (Hyper)Thermophiles

H. Santos, P. Lamosa, N. Borges, 2007 .

Organic solutes in Rubrobacter xylanophilus: the first example of di-myo-inositol-phosphate in a thermophile

H. Santos, Nuno Empadinhas, M. Costa, 2007, Extremophiles.

Protein Stabilisation by Compatible Solutes: Effect of Mannosylglycerate on Unfolding Thermodynamics and Activity of Ribonuclease A

S. Knapp, H. Santos, R. Ladenstein, 2003, Chembiochem : a European journal of chemical biology.

Diversity of bacteria and archaea from two shallow marine hydrothermal vents from Vulcano Island

F. Robb, P. Forterre, H. Santos, 2017, Extremophiles.

Mannosylglycerate and Di-myo-Inositol Phosphate Have Interchangeable Roles during Adaptation of Pyrococcus furiosus to Heat Stress

H. Santos, M. Adams, Patrick M. McTernan, 2014, Applied and Environmental Microbiology.

Interchangeable Roles during Adaptation of Pyrococcus furiosus to

H. Santos, M. Adams, Patrick M. McTernan, 2014 .

Compatible Solutes of the Hyperthermophile Palaeococcus ferrophilus: Osmoadaptation and Thermoadaptation in the Order Thermococcales

H. Santos, M. D. da Costa, C. Neves, 2005, Applied and Environmental Microbiology.

Thermococcales Thermoadaptation in the Order : Osmoadaptation and ferrophilus Palaeococcus Hyperthermophile Compatible Solutes of the

H. Santos, M. Costa, C. Neves, 2005 .

Stress response by solute accumulation in archaea.

H. Santos, V. Müller, R. Spanheimer, 2005, Current opinion in microbiology.

The Fate of Acetic Acid during Glucose Co-Metabolism by the Spoilage Yeast Zygosaccharomyces bailii

H. Santos, M. Sousa, C. Leão, 2012, PloS one.

Combined effect of the growth temperature and salinity of the medium on the accumulation of compatible solutes by Rhodothermus marinus and Rhodothermus obamensis

H. Santos, M. D. da Costa, R. Wait, 1999, Extremophiles.

Response of a strict anaerobe to oxygen: survival strategies in Desulfovibrio gigas.

H. Santos, P. Moradas-Ferreira, J. Legall, 2003, Microbiology.

Purification and characterization of an NADH-rubredoxin oxidoreductase involved in the utilization of oxygen by Desulfovibrio gigas.

H. Santos, M. Y. Liu, J. Legall, 1993, European journal of biochemistry.

Sucrose Synthesis in Nitrate Fed Detached Maize and Wheat Leaves as Analyzed by 13C-NMR

H. Santos, S. Amâncio, I. Stulen, 2000 .

Intramolecular Fluorescence Quenching of Tyrosine by the Peptide α-Carbonyl Group Revisited

H. Santos, Rita Ventura, C. Maycock, 2004 .

Proteins containing the factor F430 from methanosarcina barkeri and methanobacterium thermoautotrophicum

H. Santos, I. Moura, H. D. Peck, 1983 .

Role of Periplasmic Trehalase in Uptake of Trehalose by the Thermophilic Bacterium Rhodothermus marinus

H. Santos, W. Boos, Luís L. Fonseca, 2008, Journal of bacteriology.

Aerobic metabolism of carbon reserves by the "obligate anaerobe" Desulfovibrio gigas.

H. Santos, M. Y. Liu, J. Legall, 1993, Biochemical and biophysical research communications.

Compatible Solutes in the Thermophilic Bacteria Rhodothermus marinus and "Thermus thermophilus"

H. Santos, M. D. da Costa, C. Manaia, 1995, Applied and environmental microbiology.

X-ray structure of a CDP-alcohol phosphatidyltransferase membrane enzyme and insights into its catalytic mechanism

H. Santos, E. Round, V. Gordeliy, 2014, Nature Communications.

Biosynthetic Pathways of Inositol and Glycerol Phosphodiesters Used by the Hyperthermophile Archaeoglobus fulgidus in Stress Adaptation

H. Santos, Rita Ventura, C. Maycock, 2006, Journal of bacteriology.

Effects of ethanol on Saccharomyces cerevisiae as monitored by in vivo 31P and 13C nuclear magnetic resonance

H. Santos, M. Loureiro-Dias, 2004, Archives of Microbiology.

8 Characterization and Quantification of Compatible Solutes in (Hyper)thermophilic Microorganisms

H. Santos, P. Lamosa, N. Borges, 2006 .

Pathways for utilization of carbon reserves in Desulfovibrio gigas under fermentative and respiratory conditions

H. Santos, J. Legall, A. V. Xavier, 1997, Journal of bacteriology.

A unique glyceryl diglycoside identified in the thermophilic, radiation-resistant bacterium Rubrobacter xylanophilus

H. Santos, M. Costa, Ana Nobre, 2015, Extremophiles.

In vivo nuclear magnetic resonance studies of the metabolism of methanol and pyruvate by Methanosarcina barkeri

H. Santos, J. Legall, Paula Fareleha, 1990 .

High-resolution structure of an atypical α-phosphoglucomutase related to eukaryotic phosphomannomutases.

A. Neves, H. Santos, P. Matias, 2013, Acta crystallographica. Section D, Biological crystallography.

Two-dimensional NMR studies of electron transfer in cytochrome c3

H. Santos, D. Turner, A. V. Xavier, 1984 .

Four quartets. Application to two-dimensional NMR

H. Santos, D. Turner, A. V. Xavier, 1984 .

High-affinity maltose/trehalose transport system in the hyperthermophilic archaeon Thermococcus litoralis

H. Santos, W. Boos, K. Xavier, 1996, Journal of bacteriology.

Structural basis for phosphatidylinositol-phosphate biosynthesis

H. Santos, W. Hendrickson, L. Shapiro, 2015, Nature Communications.

Trehalose, a temperature‐ and salt‐induced solute with implications in pathobiology of Acinetobacter baumannii

H. Santos, V. Müller, P. Lamosa, 2017, Environmental microbiology.

Effect of pH on axial ligand coordination of cytochrome c" from Methylophilus methylotrophus and horse heart cytochrome c.

H. Santos, M. Coletta, G. Smulevich, 2000, Biochemistry.

Trehalose-6-phosphate mediated phenotypic change in Acinetobacter baumannii.

H. Santos, V. Müller, B. Averhoff, 2020, Environmental microbiology.

A variant of the hyperthermophile Archaeoglobus fulgidus adapted to grow at high salinity.

R. Huber, H. Santos, M. D. da Costa, 2003, FEMS microbiology letters.

Mannitol-1-phosphate dehydrogenases/phosphatases: a family of novel bifunctional enzymes for bacterial adaptation to osmotic stress.

V. de Crécy-Lagard, H. Santos, V. Müller, 2015, Environmental microbiology.

[39] In vivo nuclear magnetic resonance in study of physiology of sulfate-reducing bacteria

H. Santos, J. Legall, A. V. Xavier, 1994 .

A Unique (cid:2) -1,2-Mannosyltransferase of Thermotoga maritima That Uses Di- myo -Inositol Phosphate as the Mannosyl Acceptor (cid:1)

H. Santos, P. Lamosa, N. Borges, 2009 .

Nmr Studies Of Wine Chemistry And Wine Bacteria

H. Santos, A. Ramos, 1999 .

Purification and crystallographic studies of a putative carbohydrate-binding module from the Ruminococcus flavefaciens FD-1 endoglucanase Cel5A.

H. Santos, C. Fontes, S. Najmudin, 2015, Acta crystallographica. Section F, Structural biology communications.

Crystallization and preliminary X-ray diffraction analysis of a trimodular endo-β-1,4-glucanase (Cel5B) from Bacillus halodurans.

K. Sakka, H. Santos, C. Fontes, 2014, Acta crystallographica. Section F, Structural biology communications.

Nutraceutical production by propionibacteria

H. Santos, J. Hugenholtz, E. Smid, 2002 .

Glutamine synthetase 2 is not essential for biosynthesis of compatible solutes in Halobacillus halophilus

H. Santos, V. Müller, I. Hänelt, 2014, Front. Microbiol..

The High-Affinity Maltose/Trehalose ABC Transporter in the Extremely Thermophilic Bacterium Thermus thermophilus HB27 Also Recognizes Sucrose and Palatinose

H. Santos, W. Boos, A. Henne, 2005, Journal of bacteriology.

Isolation of P590 from Methanosarcina barkeri: evidence for the presence of sulfite reductase activity.

H. Santos, J. Moura, I. Moura, 1982, Biochemical and biophysical research communications.

Ligand orientation and haem electronic structure in ferricytochrome c′′ from Methylophilus methylotrophus studied by 13C NMR

H. Santos, D. Turner, H. Costa, 1996, European Biophysics Journal.

Metabolic Pathway for Propionate Utilization by Phosphorus-Accumulating Organisms in Activated Sludge: 13C Labeling and In Vivo Nuclear Magnetic Resonance

H. Santos, M. Reis, L. S. Serafim, 2003, Applied and Environmental Microbiology.

Resonance Labeling and In Vivo Nuclear Magnetic C 13 Organisms in Activated Sludge : Utilization by Phosphorus-Accumulating Metabolic Pathway for Propionate

H. Santos, M. Reis, L. S. Serafim, 2002 .

A difference method for the reduction of “auto” peaks in autocorrelation spectra

H. Santos, D. Turner, A. V. Xavier, 1983 .

Electron-dense granules in Desulfovibrio gigas do not consist of inorganic triphosphate but of a glucose pentakis(diphosphate).

H. Santos, T. Hansen, C. Hensgens, 1996, European journal of biochemistry.

NMR studies of electron transfer mechanisms in a protein with interacting redox centres: Desulfovibrio gigas cytochrome c3.

H. Santos, J. Moura, I. Moura, 1984, European journal of biochemistry.

Overproduction, purification, crystallization and preliminary X-ray characterization of the family 46 carbohydrate-binding module (CBM46) of endo-β-1,4-glucanase B (CelB) from Bacillus halodurans.

K. Sakka, H. Santos, C. Fontes, 2014, Acta crystallographica. Section F, Structural biology communications.

Overexpression, crystallization and preliminary X-ray crystallographic analysis of glucuronoxylan xylanohydrolase (Xyn30A) from Clostridium thermocellum.

H. Santos, F. Freire, M. Romão, 2013, Acta crystallographica. Section F, Structural biology and crystallization communications.

Production and crystallization of α-phosphoglucomutase from Lactococcus lactis.

A. Neves, H. Santos, P. Nogly, 2012, Acta crystallographica. Section F, Structural biology and crystallization communications.

Production, crystallization and preliminary X-ray analysis of CTP:inositol-1-phosphate cytidylyltransferase from Archaeoglobus fulgidus.

H. Santos, M. Archer, José A. Brito, 2010, Acta crystallographica. Section F, Structural biology and crystallization communications.

Conformation of purine mononucleotides by H{H} and P{H} nuclear Overhauser effects

H. Santos, C. Geraldes, A. V. Xavier, 1983 .

A proton relaxation study of the conformations of some purine mononucleotides in aqueous solution

H. Santos, C. Geraldes, A. V. Xavier, 1982 .

Ferredoxin from Methanosarcina barkeri: evidence for the presence of a three-iron center.

H. Santos, J. Moura, I. Moura, 1982, European journal of biochemistry.

A 31P nuclear magnetic resonance study of phosphate levels in roots of ectomycorrhizal and nonmycorrhizal plants of Castanea sativa Mill.

H. Santos, A. Martins, M. Pais, 1999, Trees.

Involvement of free and conjugated polyamines and free amino acids in the adventitious rooting of micropropagated cork oak and grapevine shoots

H. Santos, S. Amâncio, C. Neves, 2002 .

Combined transcriptomics–metabolomics profiling of the heat shock response in the hyperthermophilic archaeon Pyrococcus furiosus

H. Santos, J. Portais, G. Graça, 2018, Extremophiles.

Involvement of a labile axial histidine in coupling electron and proton transfer in Methylophilus methylotrophus cytochrome c''.

H. Santos, A. V. Xavier, H. Costa, 1992, European journal of biochemistry.

Effect of extracellular acidification on the activity of plasma membrane ATPase and on the cytosolic and vacuolar pH of Saccharomyces cerevisiae.

H. Santos, I. Sá-Correia, V. Carmelo, 1997, Biochimica et biophysica acta.

Assignment of the redox potentials to the four haems in Desulfovibrio vulgaris cytochrome c 3 by 2D‐NMR

H. Santos, D. Turner, J. Legall, 1992, FEBS letters.

Elucidation of the multiple equilibria of malvin in aqueous solution by one- and two-dimensional NMR

H. Santos, J. C. Lima, F. Pina, 1993 .

Engineering Lactococcus lactis for Production of Mannitol: High Yields from Food-Grade Strains Deficient in Lactate Dehydrogenase and the Mannitol Transport System

Ana Rute Neves, Helena Santos, A. Neves, 2004, Applied and Environmental Microbiology.

Excited state proton transfer in synthetic flavylium salts: 4-methyl-7-hydroxyflavylium and 4′,7-dihydroxyflavylium Example of a four-level molecular device to invert the population of the excited state

H. Santos, M. Maestri, R. Ballardini, 1998 .

Color stabilization of malvidin 3-glucoside: self-aggregation of the flavylium cation and copigmentation with the Z-chalcone form

H. Santos, J. C. Lima, A. Maçanita, 1998 .

Characterization and NMR studies of a novel cytochrome c isolated from Methylophilus methylotrophus which shows a redox-linked change of spin state

H. Santos, D. Turner, 1988 .

Biosynthesis of Mannosylglycerate in the Thermophilic Bacterium Rhodothermus marinus

H. Santos, Nuno Empadinhas, M. D. da Costa, 1999, The Journal of Biological Chemistry.

The use of the n-(9-anthroyloxy) stearic acid to probe the water content of sodium dodecyl sulfate, dodecyltimethylammonium chloride, and triton X-100 micelles

H. Santos, E. Melo, S. Costa, 1991 .

Subcellular metabolic organization in the context of dynamic energy budget and biochemical systems theories

S. Kooijman, A. Neves, H. Santos, 2010, Philosophical Transactions of the Royal Society B: Biological Sciences.

Overview on sugar metabolism and its control in Lactococcus lactis - The input from in vivo NMR

Oscar P. Kuipers, Jan Kok, Ana Rute Neves, 2005 .

Effect of Different NADH Oxidase Levels on Glucose Metabolism by Lactococcus lactis: Kinetics of Intracellular Metabolite Pools Determined by In Vivo Nuclear Magnetic Resonance

Michiel Kleerebezem, Ana Rute Neves, Jeroen Hugenholtz, 2002, Applied and Environmental Microbiology.

Photochromism of the synthetic 4',7-dihydroxyflavylium chloride

H. Santos, R. Brouillard, J. C. Lima, 1994 .

The 9-Anthroate chromophore as a fluorescent probe for water

H. Santos, E. Melo, A. Maçanita, 1989 .

Pseudovitamin B 12 is the corrinoid produced by Lactobacillus reuteri CRL1098 under anaerobic conditions

W. D. de Vos, H. Santos, J. Hugenholtz, 2007, FEBS letters.

Comparison of glucose fermentation by suspended and gel‐entrapped yeast cells: An in vivo nuclear magnetic resonance study

H. Santos, J. Cabral, M. A. Taipa, 1993, Biotechnology and bioengineering.

Proton NMR studies of horse ferricytochrome c Completion of the assignment of the well resolved hyperfine shifted resonances

H. Santos, D. Turner, 1987, FEBS letters.

Protein Stabilization by Osmolytes from Hyperthermophiles

H. Santos, J. C. Lima, M. Bastos, 2004, Journal of Biological Chemistry.

An overview of the role and diversity of compatible solutes in Bacteria and Archaea.

H. Santos, M. D. da Costa, M. Costa, 1998, Advances in biochemical engineering/biotechnology.

Uniport of anionic citrate and proton consumption in citrate metabolism generates a proton motive force in Leuconostoc oenos

H. Santos, A. Ramos, B. Poolman, 1994, Journal of bacteriology.

Effects of 2-deoxyglucose on Saccharomyces cerevisiae as observed by in vivo 31P-NMR.

H. Santos, M. Loureiro-Dias, 1989, FEMS microbiology letters.

Pathway and regulation of erythritol formation in Leuconostoc oenos

H. Santos, E. Schaftingen, M. Veiga-da-Cunha, 1993, Journal of bacteriology.

Role in Protein Stabilization

H. Santos, P. Lamosa, M. L. D. L. Paz, 2007 .

Compatible solutes of microorganisms from hot, marine environments:

H. Santos, P. Lamosa, 2007 .

The lactate dehydrogenases encoded by the ldh and ldhB genes in Lactococcus lactis exhibit distinct regulation and catalytic properties − comparative modeling to probe the molecular basis

C. Soares, A. Neves, H. Santos, 2007, The FEBS journal.

Identification of novel esterase-active enzymes from hot environments by use of the host bacterium Thermus thermophilus

H. Santos, W. Liebl, A. Angelov, 2015, Front. Microbiol..

Annual changes in the concentration of minerals and organic compounds of Quercus suber leaves

H. Santos, C. Ricardo, P. Lamosa, 2006 .

Tracking local conformational changes of ribonuclease A using picosecond time-resolved fluorescence of the six tyrosine residues.

H. Santos, E. Paci, J. C. Lima, 2007, Biophysical journal.

Biochemical and genetic characterization of the pathways for trehalose metabolism in Propionibacterium freudenreichii, and their role in stress response.

H. Santos, Filipa S Cardoso, N. Borges, 2007, Microbiology.

A Gene from the Mesophilic Bacterium Dehalococcoides ethenogenes Encodes a Novel Mannosylglycerate Synthase

H. Santos, S. Zinder, Nuno Empadinhas, 2004, Journal of bacteriology.

A New Pathway for Mannitol Metabolism in Yeasts Suggests a Link to the Evolution of Alcoholic Fermentation

H. Santos, P. Gonçalves, M. Leandro, 2019, Front. Microbiol..

Contribution of Citrate Metabolism to the Growth of Lactococcus lactis CRL264 at Low pH

A. Neves, H. Santos, C. Sánchez, 2007, Applied and Environmental Microbiology.

Compatible solutes of organisms that live in hot saline environments.

H. Santos, M. D. da Costa, 2002, Environmental microbiology.

Pathway for the Synthesis of Mannosylglycerate in the Hyperthermophilic Archaeon Pyrococcus horikoshii

H. Santos, Nuno Empadinhas, M. D. da Costa, 2001, The Journal of Biological Chemistry.

1,3-1,4-β-Glucanases and not 1,4-β-glucanases improve the nutritive value of barley-based diets for broilers

H. Santos, L. Ferreira, C. Fontes, 2016 .

Leuconostoc ficulneum sp. nov., a novel lactic acid bacterium isolated from a ripe fig, and reclassification of Lactobacillus fructosus as Leuconostoc fructosum comb. nov.

H. Santos, A. Ramos, F. Rainey, 2002, International journal of systematic and evolutionary microbiology.

Di-myo-inositol phosphate and novel UDP-sugars accumulate in the extreme hyperthermophile Pyrolobus fumarii

R. Huber, H. Santos, P. Lamosa, 2008, Extremophiles.

A family 11 carbohydrate-binding module (CBM) improves the efficacy of a recombinant cellulase used to supplement barley-based diets for broilers at lower dosage rates

H. Santos, J. Prates, L. Ferreira, 2008, British poultry science.

A novel limb in the osmoregulatory network of Methanosarcina mazei Gö1: Nε‐acetyl‐β‐lysine can be substituted by glutamate and alanine

Helena Santos, Volker Müller, H. Santos, 2009 .

Genetic analysis of the role of the ABC transporter Ota and Otb in glycine betaine transport in Methanosarcina mazei Gö1

Helena Santos, Volker Müller, H. Santos, 2008, Archives of Microbiology.

and Growth at High Salinity-Lysine β-Acetyl-ε N for the Biosynthesis of Archaea Are Salt Induced and Are Essential Acetyltransferase Genes of Methanogenic-Lysine β Lysine-2 , 3-Aminomutase and

H. Santos, G. Gottschalk, V. Müller, 2003 .

In vivo31P‐NMR studies of Desulfovibrio species

H. Santos, J. Legall, A. V. Xavier, 1991 .

Yeast Life-Span Extension by Calorie Restriction Is Independent of NAD Fluctuation

Ana Rute Neves, Siva Lavu, Helena Santos, 2003, Science.

NMR Redox Studies of Desrulfovibrio vulgaris Cytochrome c3

H. Santos, G. Moore, J. Moura, 1982 .

Biochemical basis for glucose-induced inhibition of malolactic fermentation in Leuconostoc oenos

H. Santos, A. Ramos, M. Veiga-da-Cunha, 1997, Journal of bacteriology.

Nodulation in clover roots : correlation with vacuolar pH

H. Santos, A. P. Oliveira, J. F. Marques, 1992 .

Methods for detection and visualization of intracellular polymers stored by polyphosphate-accumulating microorganisms.

Maria A M Reis, Helena Santos, Caterina Levantesi, 2002, Journal of microbiological methods.

Salinisphaerashabanensis gen. nov., sp. nov., a novel, moderately halophilic bacterium from the brine–seawater interface of the Shaban Deep, Red Sea

Robert Huber, Wolfgang Eder, Helena Santos, 2003, Extremophiles.

Effects of Temperature, Salinity, and Medium Composition on Compatible Solute Accumulation byThermococcus spp

H. Santos, M. D. da Costa, L. O. Martins, 1998, Applied and Environmental Microbiology.

Mannosylglycerate: structural analysis of biosynthesis and evolutionary history

H. Santos, P. Matias, N. Borges, 2014, Extremophiles.

Potential applications of stress solutes from extremophiles in protein folding diseases and healthcare

H. Santos, I. Bagyan, N. Borges, 2016, Extremophiles.

NMR structure of Desulfovibrio gigas rubredoxin: a model for studying protein stabilization by compatible solutes

H. Santos, P. Lamosa, D. Turner, 2001, Extremophiles.

Evolution of the biosynthesis of di-myo-inositol phosphate, a marker of adaptation to hot marine environments.

Pedro L. Fernandes, H. Santos, H. Dopazo, 2012, Environmental microbiology.

The Bacterium Thermus thermophilus, Like Hyperthermophilic Archaea, Uses a Two-Step Pathway for the Synthesis of Mannosylglycerate

H. Santos, A. Henne, Nuno Empadinhas, 2003, Applied and Environmental Microbiology.

Maltose Metabolism in the Hyperthermophilic Archaeon Thermococcus litoralis: Purification and Characterization of Key Enzymes

H. Santos, W. Boos, K. Xavier, 1999, Journal of bacteriology.

Rubredoxin oxidase, a new flavo-hemoprotein, is the site of oxygen reduction to water by the “strict anaerobe”: Desulfovibrio gigas

H. Santos, M. Y. Liu, Liang Chen, 1993 .

Rubredoxin oxidase, a new flavo-hemo-protein, is the site of oxygen reduction to water by the "strict anaerobe" Desulfovibrio gigas.

H. Santos, M. Y. Liu, J. Legall, 1993, Biochemical and biophysical research communications.

Environmental Regulation of Methanol and Formaldehyde Metabolism by Methylophilus methylotrophus

H. Santos, D. Turner, C. W. Jones, 1987 .

Towards Enhanced Galactose Utilization by Lactococcus lactis

A. Neves, H. Santos, O. Kuipers, 2010, Applied and Environmental Microbiology.

Enzyme Basis for pH Regulation of Citrate and Pyruvate Metabolism by Leuconostoc oenos

H. Santos, A. Ramos, W. Konings, 1995, Applied and environmental microbiology.

International conference on extremophiles 2014

H. Santos, M. Adams, H. Atomi, 2014, Extremophiles.

Enhancement of trehalose production in dairy propionibacteria through manipulation of environmental conditions.

Jeroen Hugenholtz, Helena Santos, H. Santos, 2004, International journal of food microbiology.

Characterization of the haem environment in Methylophilus methylotrophus ferricytochrome c" by 1H-NMR.

H. Santos, H. Costa, D. Turner, 1993, European journal of biochemistry.

Citrate and Sugar Cofermentation in Leuconostoc oenos, a (sup13)C Nuclear Magnetic Resonance Study

H. Santos, A. Ramos, H Santos, 1996, Applied and environmental microbiology.

Electron transfer mechanism studies of cytochrome c3: pH dependence of the redox equilibria

H. Santos, J. Moura, J. Legall, 1983 .

An unusual conformation of the methionine haem ligand in cytochrome cL established by two-dimensional 1H-NMR.

H. Santos, H. Costa, D. Turner, 1994, European journal of biochemistry.

Determination of the methionine haem ligand conformation in cytochrome cH from Methylophilus methylotrophus by two‐dimensional 1H NMR

H. Santos, D. Turner, 1993 .

Pitfalls in assigning heme axial coordination by EPR

Antonio Pedro Aguiar, H. Santos, M. Teixeira, 1993, FEBS letters.

In vivo 31P- and 13C-NMR studies of ATP synthesis and methane formation by Methanosarcina barkeri.

H. Santos, H. D. Peck, J. Legall, 1989, European journal of biochemistry.

Characterization of the improved sensitivity obtained using a flow method for oxygenating and mixing cell suspensions in NMR

H. Santos, D. Turner, 1986 .

High yield of Methylophilus methylotrophus cytochrome c by coexpression with cytochrome c maturation gene cluster from Escherichia coli.

H. Santos, E. Vijgenboom, G. Canters, 2000, Protein expression and purification.

Nitrate and Ammonium Assimilation by Roots of Maize (Zea mays L.) Seedlings as Investigated by In Vivo 15N-NMR

H. Santos, S. Amâncio, 1992 .

Different Physiological Roles of ATP- and PPi-Dependent Phosphofructokinase Isoenzymes in the Methylotrophic Actinomycete Amycolatopsis methanolica

L. Dijkhuizen, H. Santos, G. Euverink, 2001, Journal of bacteriology.

Characterization of the individual glucose uptake systems of Lactococcus lactis: mannose‐PTS, cellobiose‐PTS and the novel GlcU permease

Jan Kok, Oscar P Kuipers, Helena Santos, 2009, Molecular microbiology.

Earliest events in α-synuclein fibrillation probed with the fluorescence of intrinsic tyrosines.

Helena Santos, H. Santos, Marco A Saraiva, 2016, Journal of photochemistry and photobiology. B, Biology.

Engineering Trehalose Synthesis in Lactococcus lactis for Improved Stress Tolerance

A. Neves, H. Santos, A. Bohn, 2011, Applied and Environmental Microbiology.

Diversity of bacteria and archaea from two shallow marine hydrothermal vents from Vulcano Island

F. Robb, P. Forterre, H. Santos, 2017, Extremophiles.

Mannosylglycerate stabilizes staphylococcal nuclease with restriction of slow β‐sheet motions

H. Santos, P. Lamosa, D. Turner, 2012, Protein science : a publication of the Protein Society.

Relationship between protein stabilization and protein rigidification induced by mannosylglycerate.

H. Santos, B. García-Moreno, P. Lamosa, 2009, Journal of molecular biology.

Identification of glucoselysine-6-phosphate deglycase, an enzyme involved in the metabolism of the fructation product glucoselysine.

H. Santos, E. Van Schaftingen, P. Lamosa, 2005, The Biochemical journal.

Distribution of Genes for Synthesis of Trehalose and Mannosylglycerate in Thermus spp. and Direct Correlation of These Genes with Halotolerance

H. Santos, A. Henne, Nuno Empadinhas, 2005, Applied and Environmental Microbiology.

Relationship between Glycolysis and Exopolysaccharide Biosynthesis in Lactococcus lactis

W. D. de Vos, H. Santos, A. Ramos, 2001, Applied and Environmental Microbiology.

Structural evidence for a proton transfer pathway coupled with haem reduction of cytochrome c″ from Methylophilus methylotrophus

M. A. Carrondo, H. Santos, E. Pohl, 2006, JBIC Journal of Biological Inorganic Chemistry.

Solution structure of Methylophilus methylotrophus cytochrome c": insights into the structural basis of haem-ligand detachment.

H. Santos, L. Brennan, P. Fareleira, 2001, Journal of molecular biology.

Structural basis for the network of functional cooperativities in cytochrome c(3) from Desulfovibrio gigas: solution structures of the oxidised and reduced states.

H. Santos, M. Teodoro, D. Turner, 2000, Journal of molecular biology.

Solution structure of Desulfovibrio vulgaris (Hildenborough) ferrocytochrome c3: structural basis for functional cooperativity.

H. Santos, D. Kastrau, D. Turner, 1998, Journal of molecular biology.

Mannitol, a compatible solute synthesized by Acinetobacter baylyi in a two-step pathway including a salt-induced and salt-dependent mannitol-1-phosphate dehydrogenase.

H. Santos, V. Müller, M. Sand, 2013, Environmental microbiology.

Synthesis of GDP-Mannose and Mannosylglycerate from Labeled Mannose by Genetically Engineered Escherichia coli without Loss of Specific Isotopic Enrichment

H. Santos, W. Boos, Maria-Manuel Sampaio, 2003, Applied and Environmental Microbiology.

Synthesis of GDP-Mannose and Mannosylglycerate from Labeled Mannose by Genetically Engineered Escherichia coli without Loss of Specific Isotopic Enrichment

H. Santos, W. Boos, Maria-Manuel Sampaio, 2002 .

Kinetic analysis by in vivo 31P nuclear magnetic resonance of internal Pi during the uptake of sn-glycerol-3-phosphate by the pho regulon-dependent Ugp system and the glp regulon-dependent GlpT system

H. Santos, W. Boos, K. Xavier, 1995, Journal of bacteriology.

regulon-dependent GlpT system . regulon-dependent Ugp system and the glp uptake of sn-glycerol-3-phosphate by the pho magnetic resonance of internal Pi during the Kinetic analysis by in vivo 31 P nuclear

H. Santos, W. Boos, K. Xavier, 1995 .

Uncoupling effect of nitrite during denitrification by Pseudomonas fluorescens: An in vivo (31)P-NMR study.

J S Almeida, M A Reis, J. Almeida, 1996, Biotechnology and bioengineering.

A novel pathway for the synthesis of inositol phospholipids uses cytidine diphosphate (CDP)-inositol as donor of the polar head group.

H. Santos, N. Borges, Carla D. Jorge, 2015, Environmental microbiology.

Structural and Functional Characterization of Phosphatidylinositol-Phosphate Biosynthesis in Mycobacteria.

H. Santos, F. Mancia, O. Clarke, 2020, Journal of molecular biology.

Carbon Flux Analysis by 13C Nuclear Magnetic Resonance To Determine the Effect of CO2 on Anaerobic Succinate Production by Corynebacterium glutamicum

A. Neves, H. Santos, B. Eikmanns, 2014, Applied and Environmental Microbiology.

Bifunctional CTP:Inositol-1-Phosphate Cytidylyltransferase/CDP-Inositol:Inositol-1-Phosphate Transferase, the Key Enzyme for Di-myo-Inositol-Phosphate Synthesis in Several (Hyper)thermophiles

H. Santos, C. Maycock, Nuno Empadinhas, 2007, Journal of bacteriology.

New compatible solutes related to Di-myo-inositol-phosphate in members of the order Thermotogales

H. Santos, M. D. da Costa, L. O. Martins, 1996, Journal of bacteriology.

Thermostabilization of Proteins by Diglycerol Phosphate, a New Compatible Solute from the HyperthermophileArchaeoglobus fulgidus

C. Rodrigues-Pousada, H. Santos, C. Maycock, 2000, Applied and Environmental Microbiology.

Production of mannosylglycerate in Saccharomyces cerevisiae by metabolic engineering and bioprocess optimization

H. Santos, I. Rocha, C. Faria, 2018, Microbial Cell Factories.

A unique glyceryl diglycoside identified in the thermophilic, radiation-resistant bacterium Rubrobacter xylanophilus

H. Santos, M. Costa, P. Lamosa, 2015, Extremophiles.

Organic solutes in the deepest phylogenetic branches of the Bacteria: identification of α(1–6)glucosyl-α(1–2)glucosylglycerate in Persephonella marina

H. Santos, C. Maycock, P. Lamosa, 2012, Extremophiles.

Gluconeotrehalose is the principal organic solute in the psychrotolerant bacterium Carnobacterium strain 17-4

H. Santos, G. Antranikian, A. Mingote, 2011, Extremophiles.

Two Alternative Pathways for the Synthesis of the Rare Compatible Solute Mannosylglucosylglycerate in Petrotoga mobilis

H. Santos, Nuno Empadinhas, M. D. da Costa, 2010, Journal of bacteriology.

Design of new enzyme stabilizers inspired by glycosides of hyperthermophilic microorganisms.

H. Santos, C. Maycock, A. Mingote, 2008, Carbohydrate research.

α‐d‐Mannopyranosyl‐(1→2)‐α‐d‐glucopyranosyl‐(1→2)‐glycerate in the thermophilic bacterium Petrotoga miotherma − structure, cellular content and function

H. Santos, P. Lamosa, Carla D. Jorge, 2007 .

Occurrence of 1-Glyceryl-1-myo-Inosityl Phosphate in Hyperthermophiles

H. Santos, L. O. Martins, P. Lamosa, 2006, Applied and Environmental Microbiology.

Structural determinants of protein stabilization by solutes

H. Santos, P. Lamosa, D. Turner, 2005, The FEBS journal.

A novel limb in the osmoregulatory network of Methanosarcina mazei Gö1: N(epsilon)-acetyl-beta-lysine can be substituted by glutamate and alanine.

H. Santos, V. Müller, A. Mingote, 2009, Environmental microbiology.

Protein Stabilization by Osmolytes from Hyperthermophiles EFFECT OF MANNOSYLGLYCERATE ON THE THERMAL UNFOLDING OF RECOMBINANT NUCLEASE A FROM STAPHYLOCOCCUS AUREUS STUDIED BY PICOSECOND TIME-RESOLVED FLUORESCENCE AND CALORIMETRY*

H. Santos, J. C. Lima, M. Bastos, 2004 .

Glycerol Phosphate Cytidylyltransferase Stereospecificity Is Key to Understanding the Distinct Stereochemical Compositions of Glycerophosphoinositol in Bacteria and Archaea

H. Santos, N. Borges, Marta V. Rodrigues, 2016, Applied and Environmental Microbiology.

Thermococcus kodakarensis Mutants Deficient in Di-myo-Inositol Phosphate Use Aspartate To Cope with Heat Stress

H. Santos, H. Atomi, R. Matsumi, 2009, Journal of bacteriology.

[26] Organic solutes from thermophiles and hyperthermophiles

H. Santos, M. Costa, 2001 .

Organic solutes from thermophiles and hyperthermophiles.

H. Santos, M. S. da Costa, 2001, Methods in enzymology.

EFFECTS OF TEMPRERATURE, SALINITY, AND MEDIUM COMPOSITON ON COMPATIBLE SOLUTE ACCUMULATION BY THERMOCOCCUS SPP

H. Santos, L. O. Martins, P. Lamosa, 1998 .

Inhibition of formation of α-synuclein inclusions by mannosylglycerate in a yeast model of Parkinson's disease.

H. Santos, S. Tenreiro, T. Outeiro, 2013, Biochimica et biophysica acta.

Compatible Solutes of (Hyper)thermophiles and Their Role in Protein Stabilization

H. Santos, P. Lamosa, M. L. D. L. Paz, 2007 .

A Ramos and H Santos Magnetic Resonance Study

H. Santos, A. Ramos, 1996 .

NMR and Immobilized Cells

H. Santos, J. Portais, J. Barbotin, 2001 .

Effects of the source of inorganic nitrogen on C and N interaction in maize callus tissue: phosphoenolpyruvate carboxylase activity, cytosolic pH and 15N amino acids

H. Santos, S. Amâncio, E. Diogo, 1993 .

Structure determination of a novel cyclic phosphocompound isolated from Desulfovibrio desulfuricans.

H. Santos, D. Turner, J. Legall, 1992, The Biochemical journal.

Comparative analysis of Embden-Meyerhof and Entner-Doudoroff glycolytic pathways in hyperthermophilic archaea and the bacterium Thermotoga

H. Santos, K. Xavier, P. Schönheit, 1997, Archives of Microbiology.

Production of polyhydroxyalkanoates by a mixed culture in a sequencing batch reactor: the use of propionate as carbon source.

H. Santos, M. Reis, L. S. Serafim, 2003, Communications in agricultural and applied biological sciences.

Engineering Corynebacterium glutamicum for the production of 2,3-butanediol

Ana Rute Neves, Helena Santos, Ana Lúcia Carvalho, 2015, Microbial Cell Factories.

Elucidation of metabolic pathways in glycogen-accumulating organisms with in vivo 13C nuclear magnetic resonance.

H. Santos, Zhiguo Yuan, J. Keller, 2007, Environmental microbiology.

Different glycolytic pathways for glucose and fructose in the halophilic archaeon Halococcus saccharolyticus

H. Santos, K. Xavier, P. Schönheit, 2003, Archives of Microbiology.

Different glycolytic pathways for glucose and fructose in the halophilic archaeon Halococcus saccharolyticus

H. Santos, K. Xavier, P. Schönheit, 2000, Archives of Microbiology.

The metabolic pH response in Lactococcus lactis: An integrative experimental and modelling approach

Ursula Kummer, Lars Folke Olsen, Ana Rute Neves, 2009, Comput. Biol. Chem..

Model for carbon metabolism in biological phosphorus removal processes based on in vivo13C-NMR labelling experiments

H. Santos, M. Carrondo, M. Reis, 1996 .

Three-dimensional structure of mannosyl-3-phosphoglycerate phosphatase from Thermus thermophilus HB27: a new member of the haloalcanoic acid dehalogenase superfamily.

H. Santos, P. Matias, A. M. Esteves, 2011, Biochemistry.

Variation in levels of non-starch polysaccharides and endogenous endo-1,4-β-xylanases affects the nutritive value of wheat for poultry

H. Santos, L. Telo da Gama, L. Ferreira, 2018, British poultry science.

Fluorescence lifetimes of tyrosine residues in cytochrome c'' as local probes to study protein unfolding.

H. Santos, E. Paci, M. Noronha, 2009, The journal of physical chemistry. B.

The α-Phosphoglucomutase of Lactococcus lactis Is Unrelated to the α-d-Phosphohexomutase Superfamily and Is Encoded by the Essential Gene pgmH*

A. Neves, H. Santos, O. Kuipers, 2006, Journal of Biological Chemistry.

Stereospecificity of Corynebacterium glutamicum 2,3-butanediol dehydrogenase and implications for the stereochemical purity of bioproduced 2,3-butanediol

Ana Rute Neves, Helena Santos, A. Neves, 2016, Applied Microbiology and Biotechnology.

13C and proton NMR studies of horse cytochrome c. Systematic assignment of methyl and methine resonances in both oxidation states.

H. Santos, D. Turner, 1992, European journal of biochemistry.

High yield of mannosylglycerate production by upshock fermentation and bacterial milking of trehalose-deficient mutant Thermus thermophilus RQ-1

G. Antranikian, H. Santos, G. Antranikian, 2007, Applied Microbiology and Biotechnology.

Is the Glycolytic Flux in Lactococcus lactisPrimarily Controlled by the Redox Charge?

Ana Rute Neves, Helena Santos, A. Neves, 2002, The Journal of Biological Chemistry.

Bacterial abl-like genes: production of the archaeal osmolyte $$ {N^{\varepsilon }}{\text{ - acetyl - }}\beta {\text{ - lysine}} $$ by homologous overexpression of the yodP–kamA genes in Bacillus subtilis

H. Santos, V. Müller, E. Bremer, 2011, Applied Microbiology and Biotechnology.

Backbone and side chain 1H, 15N and 13C assignments for a thiol-disulphide oxidoreductase from the Antarctic bacterium Pseudoalteromonas haloplanktis TAC125

H. Santos, T. Collins, M. Matzapetakis, 2010, Biomolecular NMR assignments.

Construction of GH16 β-glucanase mini-cellulosomes to improve the nutritive value of barley-based diets for broilers.

H. Santos, L. Ferreira, C. Fontes, 2014, Journal of agricultural and food chemistry.

Catabolism of mannitol in Lactococcus lactis MG1363 and a mutant defective in lactate dehydrogenase.

Ana Rute Neves, Helena Santos, A. Neves, 2002, Microbiology.

Demonstration of a Novel Glycolytic Pathway in the Hyperthermophilic Archaeon Thermococcus zilligii by13C-Labeling Experiments and Nuclear Magnetic Resonance Analysis

H. Santos, M. D. da Costa, K. Xavier, 2000, Journal of bacteriology.

In vivo 31P-NMR studies of Desulfovibrio species. Detection of a novel phosphorus-containing compound.

H. Santos, J. Legall, A. V. Xavier, 1991, European journal of biochemistry.

Two-dimensional nuclear magnetic resonance of paramagnetic metalloproteins.

H. Santos, A. V. Xavier, D. Turner, 1993, Methods in enzymology.

University of Groningen Towards Enhanced Galactose Utilization by Lactococcus lactis

A. Neves, H. Santos, O. Kuipers, 2017 .

L-arabinose Metabolism in Yeasts Resonance Spectroscopy to Elucidate C Nuclear Magnetic 13 Use of in Vivo

A. Neves, H. Santos, B. Hahn-Hägerdal, 2007 .

Cytochrome c" from the obligate methylotroph Methylophilus methylotrophus, an unexpected homolog of sphaeroides heme protein from the phototroph Rhodobacter sphaeroides.

H. Santos, J. V. Van Beeumen, Y. Guisez, 1999, Biochimica et biophysica acta.

Cytochrome c'' isolated from Methylophilus methylotrophus. An example of bis-histidine-co-ordinated Fe3+ haem, with near-perpendicular orientation of the ligands.

M. Berry, H. Santos, A. Thomson, 1990, The Biochemical journal.

Exploring the Potential of Corynebacterium glutamicum to Produce the Compatible Solute Mannosylglycerate

A. Schwentner, H. Santos, B. Eikmanns, 2021, Frontiers in Bioengineering and Biotechnology.

Unfolding of ubiquitin studied by picosecond time-resolved fluorescence of the tyrosine residue.

H. Santos, J. C. Lima, M. Bastos, 2004, Biophysical journal.

High Yields of 2,3-Butanediol and Mannitol in Lactococcus lactis through Engineering of NAD+ Cofactor Recycling

A. Neves, H. Santos, C. Shearman, 2011, Applied and Environmental Microbiology.

Structural Analysis of Thermus thermophilus HB27 Mannosyl-3-phosphoglycerate Synthase Provides Evidence for a Second Catalytic Metal Ion and New Insight into the Retaining Mechanism of Glycosyltransferases*

Bruno L. Victor, H. Santos, P. Matias, 2010, The Journal of Biological Chemistry.

Cloning and sequence analysis of the gene encoding Methylophilus methylotrophus cytochrome c", a unique protein with a perpendicular orientation of the histidinyl ligands.

H. Santos, E. Vijgenboom, G. Canters, 1999, Biochimica et biophysica acta.

Crystal Structure of Archaeoglobus fulgidus CTP:Inositol-1-Phosphate Cytidylyltransferase, a Key Enzyme for Di-myo-Inositol-Phosphate Synthesis in (Hyper)Thermophiles

Clemens Vonrhein, Margarida Archer, Nuno Borges, 2011, Journal of bacteriology.

Thermal unfolding kinetics of ubiquitin in the microsecond-to-second time range probed by Tyr-59 fluorescence.

D. A. Smith, H. Santos, M. Noronha, 2010, The journal of physical chemistry. B.

Assimilation of nitrate and ammonium by sulphur deficient Zea mays cells

H. Santos, S. Amâncio, D. Clarkson, 1997 .