C. Thiemermann

发表

Dexamethasone ameliorates renal ischemia-reperfusion injury.

Sanjeev Kumar, D. Allen, J. Kieswich, 2009, Journal of the American Society of Nephrology : JASN.

Urocortin does not reduce the renal injury and dysfunction caused by experimental ischaemia/reperfusion.

N. Patel, C. Thiemermann, M. Collin, 2004, European journal of pharmacology.

Lipidomics Provides New Insight into Pathogenesis and Therapeutic Targets of the Ischemia—Reperfusion Injury

C. Thiemermann, I. Grigorov, Z. Todorović, 2021, International journal of molecular sciences.

Part I: Minimum Quality Threshold in Preclinical Sepsis Studies (MQTiPSS) for Study Design and Humane Modeling Endpoints.

C. Coopersmith, J. Marshall, C. Thiemermann, 2019, Shock.

Abandon the Mouse Research Ship? Not Just Yet!

Heinz Redl, Peter Radermacher, Yong Jiang, 2014, Shock.

Absence of endogenous interleukin-6 enhances the inflammatory response during acute pancreatitis induced by cerulein in mice.

E. Mazzon, S. Cuzzocrea, C. Thiemermann, 2002, Cytokine.

Shock States and Nitric Oxide

C. Thiemermann, H. Ruetten, 2000 .

Chapter 47 – Nitric Oxide and Septic Shock

C. Thiemermann, H. Ruetten, 2000 .

Nitric oxide and septic shock.

C. Thiemermann, Christoph Thiemermann, C. Thiemermann, 1997, General pharmacology.

Batch effect exerts a bigger influence on the rat urinary metabolome and gut microbiota than uraemia: a cautionary tale

J. Kieswich, C. Thiemermann, L. Hoyles, 2019, Microbiome.

Identification of manganese superoxide dismutase as a NO-regulated gene in rat glomerular mesangial cells by 2D gel electrophoresis.

C. Thiemermann, J. Pfeilschifter, M. McDonald, 2003, Nitric oxide : biology and chemistry.

Inhibition of IκB Kinase Attenuates the Organ Injury and Dysfunction Associated with Hemorrhagic Shock

N. Patel, C. Thiemermann, K. Brohi, 2015, Molecular medicine.

Ranolazine, a partial fatty acid oxidation inhibitor, reduces myocardial infarct size and cardiac troponin T release in the rat.

C. Thiemermann, K. Zacharowski, B. Blackburn, 2001, European journal of pharmacology.

Effects of the prostanoid EP3‐receptor agonists M&B 28767 and GR 63799X on infarct size caused by regional myocardial ischaemia in the anaesthetized rat

C. Thiemermann, K. Zacharowski, G. Hafner, 1999, British journal of pharmacology.

Reduction of myocardial infarct size with sCR1sLex, an alternatively glycosylated form of human soluble complement receptor type 1 (sCR1), possessing sialyl Lewis x

C. Thiemermann, K. Zacharowski, G. Hafner, 1999, British journal of pharmacology.

Selective activation of the prostanoid EP(3) receptor reduces myocardial infarct size in rodents.

C. Thiemermann, K. Zacharowski, G. Hafner, 1999, Arteriosclerosis, thrombosis, and vascular biology.

Endotoxin induces a second window of protection in the rat heart as determined by using p-nitro-blue tetrazolium staining, cardiac troponin T release, and histology.

C. Thiemermann, K. Zacharowski, G. Hafner, 1999, Arteriosclerosis, thrombosis, and vascular biology.

GW0742, a High Affinity PPAR-β/δ Agonist Reduces Lung Inflammation Induced by Bleomycin Instillation in Mice

E. Mazzon, S. Cuzzocrea, C. Thiemermann, 2010, International journal of immunopathology and pharmacology.

Peptidoglycan and Lipoteichoic Acid Modify Monocyte Phenotype in Human Whole Blood

S. Foster, C. Thiemermann, A. Aasen, 2001, Clinical Diagnostic Laboratory Immunology.

Inhibitors of the activity of poly (ADP‐ribose) synthetase reduce the cell death caused by hydrogen peroxide in human cardiac myoblasts

C. Thiemermann, J. Piper, J. Bowes, 1998, British journal of pharmacology.

Novel applications of recombinant erythropoietin.

C. Thiemermann, E. Sharples, M. Yaqoob, 2006, Current opinion in pharmacology.

Mechanisms of Disease: cell death in acute renal failure and emerging evidence for a protective role of erythropoietin

C. Thiemermann, E. Sharples, M. Yaqoob, 2005, Nature Clinical Practice Nephrology.

Single-dose intravenous simvastatin treatment attenuates renal injury in an experimental model of ischemia-reperfusion in the rat.

C. Thiemermann, Z. Todorović, M. Prostran, 2006, Journal of pharmacological sciences.

Selective NOD1 agonists cause shock and organ injury/dysfunction in vivo.

C. Thiemermann, T. Evans, B. Ryffel, 2007, American journal of respiratory and critical care medicine.

Inhibition of glycogen synthase kinase (GSK)-3-β improves liver microcirculation and hepatocellular function after hemorrhagic shock.

C. Thiemermann, T. Fink, D. Kubulus, 2014, European journal of pharmacology.

Reversal of the deleterious effects of chronic dietary HFCS-55 intake by PPAR-δ agonism correlates with impaired NLRP3 inflammasome activation.

C. Thiemermann, M. Yaqoob, R. Mastrocola, 2013, Biochemical pharmacology.

Definition and drivers of acute traumatic coagulopathy: clinical and experimental investigations

C. Thiemermann, M. Cohen, S. Stanworth, 2010, Journal of thrombosis and haemostasis : JTH.

Modeling Acute Traumatic Hemorrhagic Shock Injury: Challenges and Guidelines for Preclinical Studies

C. Thiemermann, S. Watts, K. Brohi, 2017, Shock.

Artesunate Protects Against the Organ Injury and Hemorrhage and Resuscitation Dysfunction Induced by Severe

M. Barnes, N. Patel, C. Thiemermann, 2016 .

Artesunate Protects Against the Organ Injury and Dysfunction Induced by Severe Hemorrhage and Resuscitation.

M. Barnes, N. Patel, C. Thiemermann, 2017, Annals of surgery.

Diadenosine Tetraphosphate Protects against Injuries Induced by Ischemia and 6-Hydroxydopamine in Rat Brain

C. Thiemermann, M. Morales, Yun Wang, 2003, The Journal of Neuroscience.

New targets of urocortin-mediated cardioprotection

M. Hubank, R. Knight, C. Thiemermann, 2010, Journal of molecular endocrinology.

Bench-to-bedside review: Erythropoietin and its derivatives as therapies in critical care

N. Patel, C. Thiemermann, K. Nandra, 2012, Critical Care.

High-Density Lipoproteins in Sepsis and Septic Shock: Metabolism, Actions, and Therapeutic Applications

C. Thiemermann, C. Hinds, A. Wu, 2004, Shock.

15d-prostaglandin J2 reduces multiple organ failure caused by wall-fragment of Gram-positive and Gram-negative bacteria.

S. Cuzzocrea, C. Thiemermann, L. Dugo, 2004, European journal of pharmacology.

THE PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR-γ LIGAND 15-DEOXYD12,14 PROSTAGLANDIN J2 REDUCES THE ORGAN INJURY IN HEMORRHAGIC SHOCK

C. Thiemermann, M. Collin, M. Abdelrahman, 2004, Shock.

The cyclopentenone prostaglandin 15‐deoxy‐Δ12,14‐ PGJ2 attenuates the development of colon injury caused by dinitrobenzene sulphonic acid in the rat

E. Mazzon, S. Cuzzocrea, C. Thiemermann, 2003, British journal of pharmacology.

Mice lacking the 110-kD isoform of poly(ADP-ribose) glycohydrolase are protected against renal ischemia/reperfusion injury.

N. Patel, E. Mazzon, S. Cuzzocrea, 2005, Journal of the American Society of Nephrology : JASN.

The effect of uraemia on the duration of arrhythmias in the context of cardioprotective ischaemic conditioning strategies

J. Kieswich, M. Raftery, C. Thiemermann, 2014, Heart Asia.

Ischemic Conditioning Protects the Uremic Heart in a Rodent Model of Myocardial Infarction

J. Kieswich, S. Harwood, M. Raftery, 2012, Circulation.

Delayed Preconditioning Induced by Lipoteichoic Acid From B. Subtilis and S. Aureus Is Not Blocked by Administration of 5-Hydroxydecanoate

C. Thiemermann, K. Zacharowski, P. Chatterjee, 2002, Shock.

Lipoteichoic acid induces delayed protection in the rat heart: A comparison with endotoxin.

S. Cuzzocrea, C. Thiemermann, J. Pfeilschifter, 2000, Arteriosclerosis, thrombosis, and vascular biology.

Protection of the myocardium by ischaemic preconditioning: mechanisms and therapeutic implications.

C. Thiemermann, G. Baxter, C. Millar, 1996, Pharmacology & therapeutics.

Sulprostone‐induced reduction of myocardial infarct size in the rabbit by activation of ATP‐sensitive potassium channels

C. Thiemermann, E. Hide, 1996, British journal of pharmacology.

Reduction by prostaglandin E1 or prostaglandin E0 of myocardial infarct size in the rabbit by activation of ATP‐sensitive potassium channels

C. Thiemermann, J. Vane, J. Piper, 1995, British journal of pharmacology.

Endothelin‐1 ‐induced reduction of myocardial infarct size by activation of ATP‐sensitive potassium channels in a rabbit model of myocardial ischaemia and reperfusion

C. Thiemermann, J. Piper, E. Hide, 1995, British journal of pharmacology.

LIVER X RECEPTOR AGONIST GW3965 DOSE-DEPENDENTLY REGULATES LPS-MEDIATED LIVER INJURY AND MODULATES POSTTRANSCRIPTIONAL TNF-&agr; PRODUCTION AND P38 MITOGEN-ACTIVATED PROTEIN KINASE ACTIVATION IN LIVER MACROPHAGES

C. Thiemermann, J. Gustafsson, F. Reinholt, 2009, Shock.

Upregulation of ICAM-1 expression on J774.2 macrophages by endotoxin involves activation of NF-kappaB but not protein tyrosine kinase: comparison to induction of iNOS.

C. Thiemermann, M. Perretti, H. Ruetten, 1999, Mediators of inflammation.

Uninephrectomy and class II PI3K‐C2β inactivation synergistically protect against obesity, insulin resistance and liver steatosis in mice

J. Kieswich, C. Thiemermann, M. Yaqoob, 2020, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

An inhibitor of poly (ADP‐ribose) synthetase activity reduces contractile dysfunction and preserves high energy phosphate levels during reperfusion of the ischaemic rat heart

C. Thiemermann, J. Docherty, J. Bowes, 1999, British journal of pharmacology.

Selective activation of E-type prostanoid(3)-receptors reduces myocardial infarct size. A novel insight into the cardioprotective effects of prostaglandins.

C. Thiemermann, K. Zacharowski, Christoph Thiemermann, 2000, Pharmacology & therapeutics.

Defibrotide reduces infarct size in a rabbit model of experimental myocardial ischaemia and reperfusion

C. Thiemermann, J. Vane, G. Thomas, 1989, British journal of pharmacology.

Protection of the ischemic myocardium from reperfusion injury by prostaglandin E1 inhibition of ischemia-induced neutrophil activation

C. Thiemermann, K. Schrör, P. Ney, 1988, Naunyn-Schmiedeberg's Archives of Pharmacology.

Stimulation of Vascular Prostacyclin Formation by Defibrotide: A New Strategy for Treatment of Acute Myocardial Ischaemia

C. Thiemermann, K. Schrör, P. Löbel, 1989 .

Agonists of peroxisome-proliferator activated receptor-alpha (clofibrate and WY14643) reduce renal ischemia/reperfusion injury in the rat.

C. Thiemermann, Y. Hattori, Z. Todorović, 2002, Medical science monitor : international medical journal of experimental and clinical research.

Biosynthesis and interaction of endothelium-derived vasoactive mediators.

C. Thiemermann, 1991, Eicosanoids.

Emerging drugs for renal failure

C. Thiemermann, P. Chatterjee, 2003, Expert opinion on emerging drugs.

GLYCOGEN SYNTHASE KINASE 3&bgr; AS A TARGET FOR THE THERAPY OF SHOCK AND INFLAMMATION

C. Thiemermann, L. Dugo, M. Collin, 2007, Shock.

Senescence and the Aging Immune System as Major Drivers of Chronic Kidney Disease

C. Thiemermann, S. Henson, Johannes Schroth, 2020, Frontiers in Cell and Developmental Biology.

The effect of iNOS deletion on hepatic gluconeogenesis in hyperdynamic murine septic shock

X. Leverve, C. Thiemermann, M. Georgieff, 2007, Intensive Care Medicine.

Inhibition of glycogen synthase kinase‐3β attenuates the development of carrageenan‐induced lung injury in mice

E. Mazzon, S. Cuzzocrea, C. Thiemermann, 2006 .

Effects of calpain inhibitor I on multiple organ failure induced by zymosan in the rat*

E. Mazzon, S. Cuzzocrea, C. Thiemermann, 2002, Critical care medicine.

Calpain inhibitor I reduces colon injury caused by dinitrobenzene sulphonic acid in the rat

E. Mazzon, S. Cuzzocrea, C. Thiemermann, 2001, Gut.

Calpain inhibitor I reduces the development of acute and chronic inflammation.

E. Mazzon, S. Cuzzocrea, C. Thiemermann, 2000, The American journal of pathology.

IκB Kinase Inhibitor Attenuates Sepsis-Induced Cardiac Dysfunction in CKD.

J. Kieswich, N. Patel, C. Thiemermann, 2017, Journal of the American Society of Nephrology : JASN.

An in vivo model of ischemia/reperfusion and inflammation of the kidneys of the rat.

C. Thiemermann, P. Chatterjee, 2003, Methods in molecular biology.

NO in Septic Shock

C. Thiemermann, C. Millar, 1997 .

Glycogen Synthase Kinase-3β Inhibition Attenuates the Development of Bleomycin-Induced Lung Injury

E. Mazzon, S. Cuzzocrea, C. Thiemermann, 2007, International journal of immunopathology and pharmacology.

Inhibitors of Poly(ADP-Ribose) Polymerase Modulate Signal Transduction Pathways and the Development of Bleomycin-Induced Lung Injury

E. Mazzon, S. Cuzzocrea, C. Thiemermann, 2005, Journal of Pharmacology and Experimental Therapeutics.

Insulin reduces the multiple organ injury and dysfunction caused by coadministration of lipopolysaccharide and peptidoglycan independently of blood glucose: Role of glycogen synthase kinase-3&bgr; inhibition*

S. Foster, D. Allen, C. Thiemermann, 2006, Critical care medicine.

Mitochondrial DNA in Acute Kidney Injury: Chicken or Egg?

C. Thiemermann, Lukas Martin, L. Martin, 2017, Shock.

Inhibition of the activity of poly (ADP-ribose) polymerase in ischemia-reperfusion injury.

C. Thiemermann, 2000, Shock.

Flipping the molecular switch for innate protection and repair of tissues: Long-lasting effects of a non-erythropoietic small peptide engineered from erythropoietin.

C. Thiemermann, A. Cerami, M. Brines, 2015, Pharmacology & therapeutics.

Elevated hepatic 11β-hydroxysteroid dehydrogenase type 1 induces insulin resistance in uremia

J. Kieswich, S. Harwood, M. Raftery, 2014, Proceedings of the National Academy of Sciences.

‘Preconditioning’ with Low Dose Lipopolysaccharide Aggravates the Organ Injury / Dysfunction Caused by Hemorrhagic Shock in Rats

N. Patel, C. Thiemermann, R. Sordi, 2015, PloS one.

Inhibition of the activity of poly(ADP ribose) synthetase reduces ischemia-reperfusion injury in the heart and skeletal muscle.

C. Thiemermann, J. Vane, F. Myint, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Inhibition of Bruton's TK regulates macrophage NF‐κB and NLRP3 inflammasome activation in metabolic inflammation

C. Thiemermann, D. Greaves, F. Chiazza, 2020, British journal of pharmacology.

Inhibition of Bruton’s tyrosine kinase reduces NF-kB and NLRP3 inflammasome activity preventing insulin resistance and microvascular disease

C. Thiemermann, D. Greaves, F. Chiazza, 2019, bioRxiv.

Cytokine‐mediated induction of cyclo‐oxygenase‐2 by activation of tyrosine kinase in bovine endothelial cells stimulated by bacterial lipopolysaccharide

C. Thiemermann, J. Vane, Y. S. Bakhle, 1995, British journal of pharmacology.

byactivation oftyrosine kinase inbovine endothelial cells stimulated by bacterial lipopolysacchari de

C. Thiemermann, J. Vane, Y. S. Bakhle, 1995 .

Beneficial effects of GW274150, a novel, potent and selective inhibitor of iNOS activity, in a rodent model of collagen-induced arthritis.

E. Mazzon, S. Cuzzocrea, C. Thiemermann, 2002, European journal of pharmacology.

Artesunate Protects Against the Organ Injury and Dysfunction Induced by Severe Hemorrhage and Resuscitation

M. Barnes, N. Patel, C. Thiemermann, 2017, Annals of surgery.

Immunohistochemistry of Kidney a-SMA, Collagen 1, and Collagen 3, in A Novel Mouse Model of Reno-cardiac Syndrome.

J. Kieswich, C. Thiemermann, M. Yaqoob, 2020, Bio-protocol.

High density lipoprotein (HDL) reduces renal ischemia/reperfusion injury.

N. Patel, S. Cuzzocrea, C. Thiemermann, 2003, Journal of the American Society of Nephrology : JASN.

The contribution of tumour necrosis factor‐α and endothelin‐1 to the increase of coronary resistance in hearts from rats treated with endotoxin

C. Thiemermann, J. Vane, T. Warner, 1995, British journal of pharmacology.

Vascular KATP channels protect from cardiac dysfunction and preserve cardiac metabolism during endotoxemia

C. Thiemermann, D. Aksentijević, A. Tinker, 2020, Journal of Molecular Medicine.

Ligands of the peroxisome proliferator‐activated receptor‐γ and heart failure

C. Thiemermann, 2004 .

A membrane-permeable radical scavenger reduces the organ injury in hemorrhagic shock.

S. Cuzzocrea, C. Thiemermann, M. McDonald, 1999, Shock.

Effects of tempol, a membrane-permeable radical scavenger, in a rodent model of carrageenan-induced pleurisy.

E. Mazzon, S. Cuzzocrea, C. Thiemermann, 2000, European journal of pharmacology.

Role of IL-6 in the pleurisy and lung injury caused by carrageenan.

G. Ciliberto, E. Mazzon, S. Cuzzocrea, 1999, Journal of immunology.

Beneficial effects of tempol, a membrane-permeable radical scavenger, in a rodent model of collagen-induced arthritis.

E. Mazzon, S. Cuzzocrea, C. Thiemermann, 2000, Arthritis and rheumatism.

Tempol, an intracelullar free radical scavenger, reduces liver injury in hepatic ischemia-reperfusion in the rat.

C. Thiemermann, B. Sepodes, M. McDonald, 2004, Transplantation proceedings.

The stable nitroxide, tempol, attenuates the effects of peroxynitrite and oxygen-derived free radicals.

S. Cuzzocrea, C. Thiemermann, M. McDonald, 2001, Critical care medicine.

ANTI-APOPTOTIC AND ANTI-INFLAMMATORY EFFECTS OF HYDROGEN SULFIDE IN A RAT MODEL OF REGIONAL MYOCARDIAL I/R

E. Mazzon, S. Cuzzocrea, C. Thiemermann, 2009, Shock.

Inhibition by spermine of the induction of nitric oxide synthase in J774.2 macrophages: requirement of a serum factor

C. Thiemermann, J. Vane, C. Szabó, 1994, British journal of pharmacology.

Free radical scavenging inhibits STAT phosphorylation following in vivo ischemia/reperfusion injury

R. Knight, C. Thiemermann, D. Latchman, 2006, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Lipoteichoic acid from Staphylococcus aureus reduces renal ischemia/reperfusion injury.

S. Cuzzocrea, C. Thiemermann, K. Zacharowski, 2002, Kidney international.

Inhibitors of Poly(ADP-Ribose) Polymerase Modulate Signal Transduction Pathways and Secondary Damage in Experimental Spinal Cord Trauma

N. Patel, E. Mazzon, S. Cuzzocrea, 2005, Journal of Pharmacology and Experimental Therapeutics.

Inhibition of the JAK/STAT Pathway With Baricitinib Reduces the Multiple Organ Dysfunction Caused by Hemorrhagic Shock in Rats

C. Thiemermann, S. Coldewey, M. Collino, 2022, bioRxiv.

The selective PPARgamma antagonist GW9662 reverses the protection of LPS in a model of renal ischemia-reperfusion.

N. Patel, C. Thiemermann, M. Yaqoob, 2005, Kidney international.

Pyrrolidine dithiocarbamate reduces renal dysfunction and injury caused by ischemia/reperfusion of the rat kidney.

S. Cuzzocrea, C. Thiemermann, M. McDonald, 2003, European journal of pharmacology.

The tyrosine kinase inhibitor tyrphostin AG 126 reduces the multiple organ failure induced by zymosan in the rat

E. Mazzon, S. Cuzzocrea, C. Thiemermann, 2002, Intensive Care Medicine.

Inhibition of the Activation of Nuclear Factor-κB as a Novel Therapeutic Approach for SIRS and Septic Shock

C. Thiemermann, G. Wray, 1998 .

Effect of calpain inhibitor I, an inhibitor of the proteolysis of IκB, on the circulatory failure and multiple organ dysfunction caused by endotoxin in the rat

C. Thiemermann, H. Ruetten, 1997, British journal of pharmacology.

HIGH-DENSITY LIPOPROTEINS REDUCE THE INTESTINAL DAMAGE ASSOCIATED WITH ISCHEMIA/REPERFUSION AND COLITIS

N. Patel, S. Cuzzocrea, C. Thiemermann, 2004, Shock.

L-Arginine infusion after ischaemia-reperfusion of rat kidney enhances lipid peroxidation.

C. Thiemermann, J. Cristol, M. Guérin, 1996, Journal of lipid mediators and cell signalling.

Elevation of serum sphingosine-1-phosphate attenuates impaired cardiac function in experimental sepsis

M. Bauer, C. Thiemermann, J. Pfeilschifter, 2016, Scientific Reports.

Attenuation of the induction of nitric oxide synthase by endogenous glucocorticoids accounts for endotoxin tolerance in vivo.

C. Thiemermann, J. Vane, M. Perretti, 1994, Proceedings of the National Academy of Sciences of the United States of America.

Isothioureas: potent inhibitors of nitric oxide synthases with variable isoform selectivity

C. Thiemermann, C. Szabó, G. Southan, 1995, British journal of pharmacology.

Beneficial effects of 5-aminoisoquinolinone, a novel, potent, water-soluble, inhibitor of poly (ADP-ribose) polymerase, in a rat model of splanchnic artery occlusion and reperfusion.

S. Cuzzocrea, C. Thiemermann, T. Genovese, 2004, European journal of pharmacology.

Prevention of the expression of inducible nitric oxide synthase by aminoguanidine or aminoethyl-isothiourea in macrophages and in the rat.

C. Thiemermann, H. Ruetten, 1996, Biochemical and biophysical research communications.

INVITED OPINION: ROLE OF NITRIC OXIDE IN HEMORRHAGIC, TRAUMATIC, AND ANAPHYLACTIC SHOCK AND THERMAL INJURY

C. Thiemermann, C. Szabó, 1994, Shock.

The Anti-Malarial Drug Artesunate Attenuates Cardiac Injury in a Rodent Model of Myocardial Infarction.

C. Thiemermann, L. Decosterd, M. Collino, 2017, Shock.

Peroxisome proliferator-activated receptor β/δ agonism protects the kidney against ischemia/reperfusion injury in diabetic rats.

C. Thiemermann, G. Miglio, M. Aragno, 2011, Free radical biology & medicine.

Induction of hypoxia in experimental murine tumors by the nitric oxide synthase inhibitor, NG-nitro-L-arginine.

C. Thiemermann, G. Adams, I. Stratford, 1994, Cancer research.

Differential effects of caspase inhibitors on the renal dysfunction and injury caused by ischemia-reperfusion of the rat kidney.

S. Cuzzocrea, C. Thiemermann, Z. Todorović, 2004, European journal of pharmacology.

Sex-specific regulation of chemokine Cxcl5/6 controls neutrophil recruitment and tissue injury in acute inflammatory states

N. Patel, C. Thiemermann, D. Gilroy, 2015, Biology of Sex Differences.

Calpain inhibitor-1 reduces renal ischemia/reperfusion injury in the rat.

S. Cuzzocrea, C. Thiemermann, K. Zacharowski, 2001, Kidney international.

Inhibitors of calpain activation (PD150606 and E-64) and renal ischemia-reperfusion injury.

E. Mazzon, S. Cuzzocrea, C. Thiemermann, 2005, Biochemical pharmacology.

Reduction of myocardial injury by the EP3 receptor agonist TEI-3356. Role of protein kinase C and of K(ATP)-channels.

C. Thiemermann, K. Zacharowski, A. Olbrich, 1999, European journal of pharmacology.

The cyclopentenone prostaglandin 15-deoxy-Delta(12,14)-prostaglandin J(2) attenuates the development of acute and chronic inflammation.

E. Mazzon, S. Cuzzocrea, C. Thiemermann, 2002, Molecular pharmacology.

Hydrogen sulfide and sulfite: novel mediators in the pathophysiology of shock and inflammation.

C. Thiemermann, M. Collin, 2005, Shock.

Lysophosphatidylcholine reduces the organ injury and dysfunction in rodent models of Gram‐negative and Gram‐positive shock

S. Foster, C. Thiemermann, B. Sepodes, 2006, British journal of pharmacology.

Reduction of experimental colitis in the rat by inhibitors of glycogen synthase kinase‐3β

C. Thiemermann, M. Collin, A. Pósa, 2006, British journal of pharmacology.

EUK-134 Reduces Renal Dysfunction and Injury Caused by Oxidative and Nitrosative Stress of the Kidney

N. Patel, S. Cuzzocrea, C. Thiemermann, 2004, American Journal of Nephrology.

Mirror, mirror on the wall, is off-pump better than on-pump at all?

C. Thiemermann, J. Roesner, 2014, Shock.

PEPTIDOGLYCAN-AN ENDOTOXIN IN ITS OWN RIGHT?

C. Thiemermann, A. Aasen, Jacob E. Wang, 2006, Shock.

The Tyrosine Kinase Inhibitor Tyrphostin AG 126 Reduces the Development of Colitis in the Rat

E. Mazzon, S. Cuzzocrea, C. Thiemermann, 2000, Laboratory Investigation.

The tyrosine kinase inhibitor tyrphostin AG126 reduces the development of acute and chronic inflammation.

E. Mazzon, S. Cuzzocrea, C. Thiemermann, 2000, The American journal of pathology.

GLYCOGEN SYNTHASE KINASE-3&bgr; INHIBITORS PROTECT AGAINST THE ORGAN INJURY AND DYSFUNCTION CAUSED BY HEMORRHAGE AND RESUSCITATION

E. Mazzon, S. Cuzzocrea, C. Thiemermann, 2006, Shock.

Glycogen synthase kinase-3beta inhibition attenuates the degree of arthritis caused by type II collagen in the mouse.

E. Mazzon, S. Cuzzocrea, C. Thiemermann, 2006, Clinical immunology.

GSK-3β inhibitors attenuate the organ injury/dysfunction caused by endotoxemia in the rat*

S. Foster, D. Allen, N. Patel, 2005, Critical care medicine.

Minimum quality threshold in pre-clinical sepsis studies (MQTiPSS): an international expert consensus initiative for improvement of animal modeling in sepsis

M. Singer, C. Deutschman, M. Bauer, 2018, Intensive Care Medicine Experimental.

Glycogen synthase kinase-3beta inhibition attenuates asthma in mice.

Wupeng Liao, W. Wong, C. Thiemermann, 2007, American journal of respiratory and critical care medicine.

Role of chelatable iron versus myoglobin in oxidative stress after crush trauma.

C. Thiemermann, S. Rehberg, M. Maybauer, 2009, Shock.

Inhibition of nitric oxide synthesis reduces the hypotension induced by bacterial lipopolysaccharides in the rat in vivo.

C. Thiemermann, J. Vane, 1990, European journal of pharmacology.

INDUCIBLE NITRIC OXIDE SYNTHASE-DEFICIENT MICE EXHIBIT RESISTANCE TO THE ACUTE PANCREATITIS INDUCED BY CERULEIN

E. Mazzon, S. Cuzzocrea, C. Thiemermann, 2002 .

Inducible Nitric Oxide Synthase-Deficient Mice Exhibit Resistance to the Acute Pancreatitis Induced by Cerulein

E. Mazzon, S. Cuzzocrea, C. Thiemermann, 2001, Shock.

Caused by Carrageenan Role of IL-6 in the Pleurisy and Lung Injury

G. Ciliberto, E. Mazzon, S. Cuzzocrea, 1999 .

Heparan Sulfate Induces Necroptosis in Murine Cardiomyocytes: A Medical-In silico Approach Combining In vitro Experiments and Machine Learning

Gerd Ascheid, Anke Schmeink, Gernot Marx, 2018, Front. Immunol..

[Heart in sepsis : Molecular mechanisms, diagnosis and therapy of septic cardiomyopathy].

C. Thiemermann, T. Schürholz, M. Derwall, 2017, Der Anaesthesist.

The synthetic antimicrobial peptide 19-2.5 attenuates septic cardiomyopathy and prevents down-regulation of SERCA2 in polymicrobial sepsis

C. Thiemermann, F. Hildebrand, K. Brandenburg, 2016, Scientific Reports.

Limitation of myocardial infarct size in the rabbit by ischaemic preconditioning is abolished by sodium 5-hydroxydecanoate.

C. Thiemermann, E. Hide, 1996, Cardiovascular research.

Tempol reduces infarct size in rodent models of regional myocardial ischemia and reperfusion.

S. Cuzzocrea, C. Thiemermann, K. Zacharowski, 1999, Free radical biology & medicine.

Annexin A1 attenuates microvascular complications through restoration of Akt signalling in a murine model of type 1 diabetes

N. Fountoulakis, C. Thiemermann, C. Reutelingsperger, 2017, Diabetologia.

Quantification of microcirculatory blood flow: a sensitive and clinically relevant prognostic marker in murine models of sepsis

C. Thiemermann, D. Treacher, D. Spina, 2014, Journal of applied physiology.

Beneficial effects of tempol, a membrane-permeable radical scavenger, in a rodent model of splanchnic artery occlusion and reperfusion.

E. Mazzon, S. Cuzzocrea, C. Thiemermann, 2000, Shock.

Tempol reduces the activation of nuclear factor-kappaB in acute inflammation.

N. Patel, S. Cuzzocrea, C. Thiemermann, 2004, Free radical research.

Membrane-permeable radical scavengers (tempol) for shock, ischemia-reperfusion injury, and inflammation

C. Thiemermann, 2003, Critical care medicine.

Peptidoglycan and Lipoteichoic Acid from Staphylococcus aureus Induce Tumor Necrosis Factor Alpha, Interleukin 6 (IL-6), and IL-10 Production in Both T Cells and Monocytes in a Human Whole Blood Model

S. Foster, C. Thiemermann, A. Aasen, 2000, Infection and Immunity.

Reconstituted High-Density Lipoprotein Attenuates Organ Injury and Adhesion Molecule Expression in a Rodent Model of Endotoxic Shock

S. Cuzzocrea, C. Thiemermann, M. McDonald, 2003, Shock.

Annexin-A1: Therapeutic Potential in Microvascular Disease

C. Thiemermann, E. Solito, G. Purvis, 2019, Front. Immunol..

Erythropoietin Reduces the Development of Experimental Inflammatory Bowel Disease

N. Patel, E. Mazzon, S. Cuzzocrea, 2004, Journal of Pharmacology and Experimental Therapeutics.

Shock States and Nitric Oxide 19

C. Thiemermann, H. Ruetten, 2022 .

Carboxy-Ptio, a Scavenger of Nitric Oxide, Selectively Inhibits the Increase in Medullary Perfusion and Improves Renal Function in Endotoxemia

C. Thiemermann, C. Millar, 2002, Shock.

Modeling Cardiac Dysfunction Following Traumatic Hemorrhage Injury: Impact on Myocardial Integrity

C. Thiemermann, K. Brohi, S. McArthur, 2019, Front. Immunol..

Inhibition of IκB Kinase at 24 Hours After Acute Kidney Injury Improves Recovery of Renal Function and Attenuates Fibrosis

N. Patel, C. Thiemermann, M. Yaqoob, 2017, Journal of the American Heart Association.

Endogenous endothelium-derived relaxing factor opposes hypoxic pulmonary vasoconstriction and supports blood flow to hypoxic alveoli in anesthetized rabbits.

C. Thiemermann, J. Vane, R. Sprague, 1992, Proceedings of the National Academy of Sciences of the United States of America.

Simvastatin reduces infarct size in a model of acute myocardial ischemia and reperfusion in the rat.

C. Thiemermann, N. Wayman, B. L. Ellis, 2003, Medical science monitor : international medical journal of experimental and clinical research.

Enhanced sphingosine-1-phosphate levels ameliorate murine septic cardiomyopathy

M. Bauer, C. Thiemermann, A. Huwiler, 2015, Intensive Care Medicine Experimental.

Erythropoietin in the intensive care unit: beyond treatment of anemia

N. Patel, C. Thiemermann, M. Yaqoob, 2011, Annals of intensive care.

Endothelin-1 stimulates the biosynthesis of tumour necrosis factor in macrophages: ET-receptors, signal transduction and inhibition by dexamethasone.

C. Thiemermann, H. Ruetten, 1997, Journal of physiology and pharmacology : an official journal of the Polish Physiological Society.

Comparison of the induction of cyclooxygenase and nitric oxide synthase by endotoxin in endothelial cells and macrophages.

C. Thiemermann, J. Vane, Y. S. Bakhle, 1995, European journal of pharmacology.

Endogenous Interleukin-6 Enhances the Renal Injury, Dysfunction, and Inflammation Caused by Ischemia/Reperfusion

N. Patel, E. Mazzon, S. Cuzzocrea, 2005, Journal of Pharmacology and Experimental Therapeutics.

GW274150, a potent and highly selective inhibitor of iNOS, reduces experimental renal ischemia/reperfusion injury.

N. Patel, S. Cuzzocrea, C. Thiemermann, 2003, Kidney international.

The effects of the endothelin ETA receptor antagonist, FR 139317, on infarct size in a rabbit model of acute myocardial ischaemia and reperfusion

C. Thiemermann, J. Vane, L. Mcmurdo, 1994, British journal of pharmacology.

The Potential Impact of Heparanase Activity and Endothelial Damage in COVID-19 Disease

C. Thiemermann, M. Dreher, Lukas Martin, 2022, Journal of clinical medicine.

THE PRODUCTION OF HYDROGEN SULFIDE LIMITS MYOCARDIAL ISCHEMIA AND REPERFUSION INJURY AND CONTRIBUTES TO THE CARDIOPROTECTIVE EFFECTS OF PRECONDITIONING WITH ENDOTOXIN, BUT NOT ISCHEMIA IN THE RAT

C. Thiemermann, M. McDonald, A. Sivarajah, 2006, Shock.

Role of tumour necrosis factor in the induction of nitric oxide synthase in a rat model of endotoxin shock

C. Thiemermann, J. Vane, M. Perretti, 1993, British journal of pharmacology.

Role for intracellular platelet‐activating factor in the circulatory failure in a model of Gram‐positive shock

C. Thiemermann, J. Vane, S. Kimpe, 1995, British journal of pharmacology.

Selectivity of nonsteroidal antiinflammatory drugs as inhibitors of constitutive and inducible cyclooxygenase.

C. Thiemermann, J. Vane, J. Mitchell, 1993, Proceedings of the National Academy of Sciences of the United States of America.

The Cyclopentenone Prostaglandin 15-Deoxy- -Prostaglandin J2 Attenuates the Development of Acute and Chronic Inflammation

E. Mazzon, S. Cuzzocrea, C. Thiemermann, 2002 .

The induction of cyclooxygenase-2 elicited by endotoxin in endothelial cells and macrophages is inhibited by prostaglandin E1 and 13,14-dihydro prostaglandin E1.

C. Thiemermann, J. Vane, P. Akarasereenont, 1995, Agents and actions. Supplements.

Endothelins release tissue plasminogen activator and prostanoids.

C. Thiemermann, J. Vane, R. Korbut, 1990, European journal of pharmacology.

Endothelin‐1 inhibits platelet aggregation in vivo: a study with 111indium‐labelled platelets

C. Thiemermann, J. Vane, C. Page, 1990, British journal of pharmacology.

Inhibition of Nitric Oxide Synthase Activity in Circulatory Shock: Friend or Foe?

C. Thiemermann, 1996 .

PEPTIDOGLYCAN OF STAPHYLOCCUS AUREUS INDUCES ENHANCED LEVELS OF MATRIX METALLOPROTEINASE-9 IN HUMAN BLOOD ORIGINATING FROM NEUTROPHILS

S. Foster, C. Thiemermann, A. Aasen, 2005, Shock.

Superoxide Dismutase Mimetics with Catalase Activity Reduce the Organ Injury in Hemorrhagic Shock

C. Thiemermann, M. McDonald, P. Chatterjee, 2002, Shock.

Relaxin Activates theL-Arginine–Nitric Oxide Pathway in Vascular Smooth Muscle Cells in Culture

C. Thiemermann, E. Masini, D. Bani, 1998 .

Nitric oxide synthase inhibitors.

C. Thiemermann, D. Siriwardena, H. Tagori, 2000, Methods in molecular medicine.

The Use of Selective Inhibitors of Inducible Nitric Oxide Synthase in Septic Shock

C. Thiemermann, 1998 .

Comparison of the effects of aminoguanidine and N omega-nitro-L-arginine methyl ester on the multiple organ dysfunction caused by endotoxaemia in the rat.

C. Thiemermann, H. Ruetten, C. Wu, 1996, European journal of pharmacology.

Peptidoglycan of Staphylococcus aureus Upregulates Monocyte Expression of CD14, Toll-Like Receptor 2 (TLR2), and TLR4 in Human Blood: Possible Implications for Priming of Lipopolysaccharide Signaling

S. Foster, C. Thiemermann, C. Hinds, 2005, Infection and Immunity.

Combined Use of Nitric Oxide and Nitric Oxide Synthase Inhibitors as a Possible Therapeutic Approach

C. Thiemermann, 2000 .

Effects of nitric oxide synthase inhibition combined with nitric oxide inhalation in a porcine model of endotoxin shock

C. Thiemermann, P. Klemm, P. Martorana, 1995, British journal of pharmacology.

Delayed activation of PPAR-β/δ improves long-term survival in mouse sepsis: effects on organ inflammation and coagulation

C. Thiemermann, M. Osuchowski, S. Bahrami, 2018, Innate immunity.

MURAMYL DIPEPTIDE ENHANCES THE RESPONSE TO ENDOTOXIN TO CAUSE MULTIPLE ORGAN INJURY IN THE ANESTHETIZED RAT

C. Thiemermann, A. Kapoor, O. Murch, 2007, Shock.

The Hemodynamic Effects of Endothelin‐1 in the Pithed Rat

C. Thiemermann, J. Vane, G. Thomas, 1989, Journal of cardiovascular pharmacology.

Increased inotropism following PARP inhibition in the setting of myocardial reperfusion injury: another piece in the jigsaw?

C. Thiemermann, D. Traber, S. Rehberg, 2010, Shock.

reduction ofmyocardial infarct size by activation ofATP-sensitive potassium channels inarabbit model ofmyocardial ischaemia andreperfusion

C. Thiemermann, J. Piper, 1995 .

Inhibition of oxygen-centered free radical formation by the stable prostacyclin-mimetic iloprost (ZK 36 374) in acute myocardial ischemia.

C. Thiemermann, E. Steinhagen-Thiessen, K. Schrör, 1984, Journal of cardiovascular pharmacology.

Inhibitors of poly (ADP-ribose) synthetase protect rat proximal tubular cells against oxidant stress.

S. Cuzzocrea, C. Thiemermann, P. Chatterjee, 1999, Kidney international.

Erythropoietin attenuates cardiac dysfunction in experimental sepsis in mice via activation of the β-common receptor

N. Patel, C. Thiemermann, P. Radermacher, 2013, Disease Models & Mechanisms.

Tissue Protective Activities of Erythropoietin

N. Patel, C. Thiemermann, M. Yaqoob, 2010 .

The mechanism of the inhibitory effect of polyamines on the induction of nitric oxide synthase: role of aldehyde metabolites

C. Thiemermann, J. Vane, C. Szabó, 1994, British journal of pharmacology.

Tyrphostin reduces the organ injury in haemorrhagic shock: role of inducible nitric oxide synthase.

S. Cuzzocrea, C. Thiemermann, M. McDonald, 2003, Resuscitation.

Effects of tyrphostins and genistein on the circulatory failure and organ dysfunction caused by endotoxin in the rat: a possible role for protein tyrosine kinase

C. Thiemermann, H. Ruetten, 1997, British journal of pharmacology.

Role of Cytochrome P4502E1 Activation in Proximal Tubular Cell Injury Induced by Hydrogen Peroxide

M. Raftery, C. Thiemermann, M. Yaqoob, 2004, Renal failure.

ALTERATIONS IN INFLAMMATORY CAPACITY AND TLR EXPRESSION ON MONOCYTES AND NEUTROPHILS AFTER CARDIOPULMONARY BYPASS

S. Foster, C. Thiemermann, C. Hinds, 2007, Shock.

Interactions between lipoteichoic acid and peptidoglycan from Staphylococcus aureus: a structural and functional analysis.

C. Thiemermann, 2002, Microbes and infection.

RECOMBINANT HUMAN ERYTHROPOIETIN PREVENTS LIPOPOLYSACCHARIDE-INDUCED VASCULAR HYPOREACTIVITY IN THE RAT

C. Thiemermann, R. Sorrentino, R. Sorrentino, 2009, Shock.

inhibition oftheexpression of inducible nitric oxide synthase incultured macrophages and intheanaesthetized rat

C. Thiemermann, Chin‐Chen Wu, 1995 .

Inhibition by N‐acetyl‐5‐hydroxytryptamine of nitric oxide synthase expression in cultured cells and in the anaesthetized rat

C. Thiemermann, M. Hecker, P. Klemm, 1995, British journal of pharmacology.

Erythropoietin in the critically ill: do we ask the right questions?

C. Thiemermann, M. Georgieff, P. Radermacher, 2012, Critical Care.

Sirolimus Interferes with the Innate Response to Bacterial Products in Human Whole Blood by Attenuation of IL‐10 Production

C. Thiemermann, A. Aasen, S. Foster, 2001, Scandinavian journal of immunology.

Effect of interleukin‐4 and interleukin‐10 on leucocyte migration and nitric oxide production in the mouse

C. Thiemermann, M. Perretti, C. Szabó, 1995, British journal of pharmacology.

Erythropoietin Preserves the Integrity and Quality of Organs for Transplantation After Cardiac Death

N. Patel, C. Thiemermann, B. Sepodes, 2011, Shock.

TEMPONE reduces renal dysfunction and injury mediated by oxidative stress of the rat kidney.

N. Patel, S. Cuzzocrea, C. Thiemermann, 2002, Free radical biology & medicine.

Inhibition of inducible nitric oxide synthase reduces renal ischemia/reperfusion injury.

N. Patel, S. Cuzzocrea, C. Thiemermann, 2002, Kidney international.

Role of Nitric Oxide in the Pathogenesis of Gram-positive Shock

C. Thiemermann, S. Kimpe, M. Kengatharan, 1996 .

Corticosteroids and cardioprotection

C. Thiemermann, 2002, Nature Medicine.

Delayed circulatory failure due to the induction of nitric oxide synthase by lipoteichoic acid from Staphylococcus aureus in anaesthetized rats

C. Thiemermann, J. Vane, C. Bryant, 1995, British journal of pharmacology.

Delayed circulatory failure duetotheinduction ofnitric oxide synthase bylipoteichoic acidfromStaphylococcus aureusinanaesthetized rats

C. Thiemermann, 1995 .

TLR9 mediates cellular protection by modulating energy metabolism in cardiomyocytes and neurons

C. Thiemermann, F. D’Acquisto, S. Takashima, 2013, Proceedings of the National Academy of Sciences.

Insulin Reduces Cerebral Ischemia/Reperfusion Injury in the Hippocampus of Diabetic Rats

C. Thiemermann, M. Aragno, G. Boccuzzi, 2009, Diabetes.

WHAT'S NEW IN SHOCK, October 2007?

C. Thiemermann, 2007 .

Imidazoquinolinone, Imidazopyridine, and Isoquinolindione Derivatives as Novel and Potent Inhibitors of the Poly(ADP-ribose) Polymerase (PARP): A Comparison with Standard PARP Inhibitors

C. Thiemermann, A. Bürkle, M. McDonald, 2008, Molecular Pharmacology.

The novel PARP inhibitor 5-aminoisoquinolinone reduces the liver injury caused by ischemia and reperfusion in the rat.

S. Cuzzocrea, C. Thiemermann, B. Sepodes, 2002, Medical science monitor : international medical journal of experimental and clinical research.

Effects of 5-aminoisoquinolinone, a water-soluble, potent inhibitor of the activity of poly (ADP-ribose) polymerase, in a rodent model of lung injury.

E. Mazzon, S. Cuzzocrea, C. Thiemermann, 2001, Biochemical pharmacology.

ACTIVATION OF THE LIVER X RECEPTOR PROTECTS AGAINST HEPATIC INJURY IN ENDOTOXEMIA BY SUPPRESSING KUPFFER CELL ACTIVATION

S. Foster, C. Thiemermann, F. Reinholt, 2006, Shock.

INTERLEUKIN‐13 IS A MORE POTENT INHIBITOR OF THE EXPRESSION OF INDUCIBLE NITRIC OXIDE SYNTHASE IN SMOOTH MUSCLE CELLS THAN IN MACROPHAGES: A COMPARISON WITH INTERLEUKIN‐4 AND INTERLEUKIN‐10

C. Thiemermann, H. Ruetten, 1995, Shock.

Nutritional support in critically ill patients: enteral, parenteral, or not at all?

C. Thiemermann, M. Clemens, P. Radermacher, 2014, Shock.

The effects of endothelium‐dependent vasodilators on cardiac output and their distribution in the anaesthetized rat: a comparison with sodium nitroprusside

C. Thiemermann, J. Vane, G. Thomas, 1988, British journal of pharmacology.

Inhibitors of poly (ADP-ribose) synthetase protect rat cardiomyocytes against oxidant stress.

C. Thiemermann, M. McDonald, J. Piper, 1999, Cardiovascular research.

Reduction of myocardial reperfusion injury by an inhibitor of poly (ADP-ribose) synthetase in the pig.

C. Thiemermann, H. Ruetten, P. Martorana, 1998, European journal of pharmacology.

The endothelin ETB receptor agonist, IRL 1620, causes vasodilatation and inhibits ex vivo platelet aggregation in the anaesthetised rabbit.

C. Thiemermann, J. Vane, L. Mcmurdo, 1994, European journal of pharmacology.

Mediation of endothelin‐1‐induced inhibition of platelet aggregation via the ETB receptor

C. Thiemermann, J. Vane, P. Lidbury, 1993, British journal of pharmacology.

Role for endothelial nitric oxide synthase in nitrite-induced protection against renal ischemia-reperfusion injury in mice.

N. Patel, E. Mazzon, S. Cuzzocrea, 2010, Nitric oxide : biology and chemistry.

Glycogen Synthase Kinase-3β Inhibition Reduces Secondary Damage in Experimental Spinal Cord Trauma

E. Mazzon, S. Cuzzocrea, C. Thiemermann, 2006, Journal of Pharmacology and Experimental Therapeutics.

Glycogen Synthase Kinase-3β Inhibition Reduces Secondary Damage in Experimental Spinal Cord Trauma

E. Mazzon, S. Cuzzocrea, C. Thiemermann, 2006, Journal of Pharmacology and Experimental Therapeutics.

5-Aminoisoquinolinone reduces renal injury and dysfunction caused by experimental ischemia/reperfusion.

S. Cuzzocrea, C. Thiemermann, M. McDonald, 2004, Kidney international.

Effects of nitric oxide synthase inhibition

C. Thiemermann, P. Klemm, P. Martorana, 2006 .

Themechanism oftheinhibitory effect ofpolyamines on the induction ofnitric oxide synthase: role ofaldehyde metabolites

C. Thiemermann, 1994 .

Roleoftumour necrosis factor intheinduction ofnitric oxide synthase inaratmodelofendotoxin shock

C. Thiemermann, Chin‐Chen Wu, 1993 .

Junctional Adhesion Molecule–C Mediates Leukocyte Infiltration in Response to Ischemia Reperfusion Injury

P. Meda, N. Patel, C. Thiemermann, 2009, Arteriosclerosis, thrombosis, and vascular biology.

Cytokine Responses to CpG DNA in Human Leukocytes

S. Foster, C. Thiemermann, A. Aasen, 2006, Scandinavian journal of immunology.

Lipoteichoic acid is a potent inducer of cytokine production in rat and human Kupffer cells in vitro.

S. Foster, C. Thiemermann, T. Hartung, 2003, Surgical infections.

Induction of NO synthesis by lipoteichoic acid from Staphylococcus aureus in J774 macrophages: involvement of a CD14-dependent pathway.

C. Thiemermann, K. Kasai, K. Akimoto, 1997, Biochemical and biophysical research communications.

The thromboxane receptor antagonist, daltroban, protects the myocardium from ischaemic injury resulting in suppression of leukocytosis.

C. Thiemermann, K. Schrör, P. Ney, 1988, European journal of pharmacology.

Usefulness of defibrotide in protecting ischemic myocardium from early reperfusion damage.

C. Thiemermann, K. Schrör, P. Löbel, 1985, The American journal of cardiology.

Mesenchymal Stromal Cells: Current Understanding and Clinical Status

C. Thiemermann, H. Salem, Husein K Salem, 2009, Stem cells.

Glycogen synthase kinase-3β inhibition attenuates the development of ischaemia/reperfusion injury of the gut

E. Mazzon, S. Cuzzocrea, C. Thiemermann, 2007, Intensive Care Medicine.

TREATMENT WITH THE GLYCOGEN SYNTHASE KINASE-3&bgr; INHIBITOR, TDZD-8, AFFECTS TRANSIENT CEREBRAL ISCHEMIA/REPERFUSION INJURY IN THE RAT HIPPOCAMPUS

C. Thiemermann, M. Gallicchio, G. Miglio, 2008, Shock.

Effects of the PPAR-β/δ agonist GW0742 during resuscitated porcine septic shock

C. Thiemermann, M. Georgieff, P. Radermacher, 2013, Intensive Care Medicine Experimental.

Membrane-permeable radical scavenger, tempol, reduces multiple organ injury in a rodent model of Gram-positive shock

S. Foster, S. Cuzzocrea, C. Thiemermann, 2000, Critical care medicine.

Pharmacology of the prostaglandin EP3 receptor agonist TEI-3356

C. Thiemermann, K. Zacharowski, 2006 .

Models of coronary artery occlusion and reperfusion for the discovery of novel antiischemic and antiinflammatory drugs for the heart.

C. Thiemermann, M. McDonald, P. Chatterjee, 2003, Methods in molecular biology.

The Effect of β2-Adrenoceptor Agonists on Leucocyte-Endothelial Adhesion in a Rodent Model of Laparotomy and Endotoxemia

N. Patel, C. Thiemermann, R. Pearse, 2020, Frontiers in Immunology.

A novel, potent and selective inhibitor of the activity of inducible nitric oxide synthase (GW274150) reduces the organ injury in hemorrhagic shock.

S. Cuzzocrea, C. Thiemermann, M. McDonald, 2002, Journal of physiology and pharmacology : an official journal of the Polish Physiological Society.

SELECTIVE INHIBITION OF THE ACTIVITY OF INDUCIBLE NITRIC OXIDE SYNTHASE PREVENTS THE CIRCULATORY FAILURE, BUT NOT THE ORGAN INJURY/DYSFUNCTION, CAUSED BY ENDOTOXIN

C. Thiemermann, C. Hinds, C. Millar, 1998, Shock.

Treatment of acute myocardial ischaemia with a selective antagonist of thromboxane receptors (BM 13.177)

C. Thiemermann, K. Schrör, 1986, British journal of pharmacology.

Treatment ofacutemyocardial ischaemia with a selective antagonist ofthromboxane receptors (BM13.177)

C. Thiemermann, K. Schrör, 1986 .

ICOS-Fc as innovative immunomodulatory approach to counteract inflammation and organ injury in sepsis

U. Dianzani, C. Thiemermann, C. Cifani, 2022, Frontiers in Immunology.

Nitric Oxide in Sepsis

C. Thiemermann, G. Wray, 2002 .

Nitric oxide and endothelin-1 in circulatory shock involving cytokines

C. Thiemermann, T. Warner, 1999 .

Nitric Oxide, Systemic Inflammatory Response Syndrome and Circulatory Shock

C. Thiemermann, 1999 .

Amidines are potent inhibitors of nitric oxide synthases: preferential inhibition of the inducible isoform.

C. Thiemermann, C. Szabó, A. Salzman, 1995, European journal of pharmacology.

Analysis of the signal transduction in the induction of nitric oxide synthase by lipoteichoic acid in macrophages

C. Thiemermann, S. Kimpe, M. Kengatharan, 1996, British journal of pharmacology.

Inhibition of the activation of nuclear factor kappa B to reduce myocardial reperfusion injury and infarct size.

C. Thiemermann, 2004, Cardiovascular research.

Effects of 5‐aminoisoquinolinone, a water‐soluble, potent inhibitor of the activity of poly (ADP‐ribose) polymerase on the organ injury and dysfunction caused by haemorrhagic shock

James A. Wright, C. Thiemermann, M. McDonald, 2000, British journal of pharmacology.

Effects of inhibitors of the activity of poly (ADP‐ribose) synthetase on the organ injury and dysfunction caused by haemorrhagic shock

C. Thiemermann, M. McDonald, H. Filipe, 1999, British journal of pharmacology.

Effects of inhibitors of the activity of poly (ADP‐ribose) synthetase on the liver injury caused by ischaemia‐reperfusion: a comparison with radical scavengers

C. Thiemermann, J. Bowes, 1998, British journal of pharmacology.

Nitric oxide synthase in the rat fallopian tube is regulated during the oestrous cycle.

C. Thiemermann, C. Bryant, D. Willoughby, 1995, The Journal of endocrinology.

Endothelin‐1 Releases Prostacyclin and Inhibits ex vivo Platelet Aggregation in the Anesthetized Rabbit

C. Thiemermann, J. Vane, G. Thomas, 1989, Journal of cardiovascular pharmacology.

Programme and Abstracts

N. Patel, C. Thiemermann, S. Bahrami, 2001 .

Beneficial effects and improved survival in rodent models of septic shock with S-methylisothiourea sulfate, a potent and selective inhibitor of inducible nitric oxide synthase.

C. Thiemermann, C. Szabó, G. Southan, 1994, Proceedings of the National Academy of Sciences of the United States of America.

Lipocortin 1 mediates the inhibition by dexamethasone of the induction by endotoxin of nitric oxide synthase in the rat.

C. Thiemermann, J. Vane, C. Bryant, 1995, Proceedings of the National Academy of Sciences of the United States of America.

Dopexamine can attenuate the inflammatory response and protect against organ injury in the absence of significant effects on hemodynamics or regional microvascular flow

N. Patel, C. Thiemermann, R. Pearse, 2013, Critical Care.

The role of cycloxygenase-2 in the rodent kidney following ischaemia/reperfusion injury in vivo.

N. Patel, E. Mazzon, S. Cuzzocrea, 2007, European journal of pharmacology.

Neuronal Nitric Oxide Synthase is Involved in Vascular Hyporeactivity and Multiple Organ Dysfunction Associated with Hemorrhagic Shock

C. Thiemermann, R. Sordi, F. Chiazza, 2016, Shock.

Evidence from receptor antagonists of an important role for ETB receptor‐mediated vasoconstrictor effects of endothelin‐1 in the rat kidney

C. Thiemermann, J. Vane, T. Warner, 1994, British journal of pharmacology.

Mediation via different receptors of the vasoconstrictor effects of endothelins and sarafotoxins in the systemic circulation and renal vasculature of the anaesthetized rat

C. Thiemermann, J. Vane, T. Warner, 1993, British journal of pharmacology.

A novel insight into the mechanism of the antithrombotic action of defibrotide.

C. Thiemermann, G. Bianchi, P. Vitte, 1992, Life sciences.

Endothelin-3: selectivity as an anti-aggregatory peptide in vivo.

C. Thiemermann, J. Vane, G. Thomas, 1989, European journal of pharmacology.

Successful treatment of acute myocardial ischaemia with teopranitol--a novel organic nitrate.

C. Thiemermann, K. Schrör, E. Smith, 1986, European heart journal.

Acute protective effects of simvastatin in the rat model of renal ischemia-reperfusion injury: it is never too late for the pretreatment.

C. Thiemermann, Z. Todorović, M. Prostran, 2008, Journal of pharmacological sciences.

The cyclopentenone prostaglandin 15-deoxy-Delta(12,14)-prostaglandin J2 ameliorates ischemic acute renal failure.

N. Patel, S. Cuzzocrea, C. Thiemermann, 2004, Cardiovascular research.

Ligands of the peroxisome proliferator-activated receptor-PPAR-a reduce myocardial infarct size.

C. Thiemermann, N. Wayman, B. L. Ellis, 2002, Medical science monitor : international medical journal of experimental and clinical research.

Intrarenal haemodynamics and renal dysfunction in endotoxaemia: effects of nitric oxide synthase inhibition

C. Thiemermann, C. Millar, 1997, British journal of pharmacology.

A superoxide dismutase mimetic with catalase activity (EUK-8) reduces the organ injury in endotoxic shock.

S. Cuzzocrea, C. Thiemermann, M. McDonald, 2003, European journal of pharmacology.

Decline in the expression of copper/zinc superoxide dismutase in the kidney of rats with endotoxic shock: Effects of the superoxide anion radical scavenger, tempol, on organ injury

C. Thiemermann, J. Pfeilschifter, A. Olbrich, 1998, British journal of pharmacology.

Reduction of infarct size in a rat model of regional myocardial ischemia and reperfusion by the synthetic peptide DAHK

C. Thiemermann, M. McDonald, D. Bar-Or, 2006, Critical care medicine.

GW0742, A HIGH-AFFINITY PPAR -&bgr;/&dgr; AGONIST, INHIBITS ACUTE LUNG INJURY IN MICE

E. Mazzon, S. Cuzzocrea, C. Thiemermann, 2010, Shock.

A Nonerythropoietic Peptide that Mimics the 3D Structure of Erythropoietin Reduces Organ Injury/Dysfunction and Inflammation in Experimental Hemorrhagic Shock

N. Patel, C. Thiemermann, A. Cerami, 2011, Molecular medicine.

Does Insulin Protect the Brain in Mice and Man with Sepsis?

C. Thiemermann, M. Osuchowski, G. Hache, 2015, Shock.

Sphingosylphosphorylcholine reduces the organ injury/dysfunction and inflammation caused by endotoxemia in the rat

E. Mazzon, S. Cuzzocrea, C. Thiemermann, 2008, Critical care medicine.

LYSOPHOSPHATIDIC ACID REDUCES THE ORGAN INJURY CAUSED BY ENDOTOXEMIA-A ROLE FOR G-PROTEIN-COUPLED RECEPTORS AND PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR-&ggr;

C. Thiemermann, M. Collin, O. Murch, 2007, Shock.

WHAT'S NEW IN SHOCK, MAY 2006

C. Thiemermann, 2006 .

Evidence for the Role of Peroxisome Proliferator-Activated Receptor-β/δ in the Development of Spinal Cord Injury

E. Mazzon, S. Cuzzocrea, C. Thiemermann, 2010, Journal of Pharmacology and Experimental Therapeutics.

Evidence for the role of PPAR‐β/δ in the development of spinal cord injury

E. Mazzon, S. Cuzzocrea, C. Thiemermann, 2010 .

EFFECTS OF INHIBITORS OF POLY(ADP-RIBOSE) SYNTHETASE ACTIVITY ON HYPOTENSION AND MULTIPLE ORGAN DYSFUNCTION CAUSED BY ENDOTOXIN

C. Thiemermann, C. Hinds, G. Wray, 1998, Shock.

Caught between a rock and a hard place: seeking an optimal resuscitation strategy for hemorrhaging patients with lung injury.

C. Thiemermann, P. Radermacher, M. Osuchowski, 2014, Shock.

Is endothelin-1 the regulator of myofibroblast contraction during wound healing?

C. Thiemermann, R. Corder, 1992, Laboratory investigation; a journal of technical methods and pathology.

Effects of the endothelin receptor antagonist, SB 209670, on circulatory failure and organ injury in endotoxic shock in the anaesthetized rat

C. Thiemermann, J. Vane, H. Ruetten, 1996, British journal of pharmacology.

Downregulation of SPARC expression is mediated by nitric oxide in rat mesangial cells and during endotoxemia in the rat.

C. Thiemermann, J. Pfeilschifter, W. Eberhardt, 2000, Journal of the American Society of Nephrology : JASN.

The selective guanylate cyclase inhibitor ODQ reduces multiple organ injury in rodent models of Gram-positive and Gram-negative shock

S. Foster, S. Cuzzocrea, C. Thiemermann, 2001, Critical care medicine.

Nitric oxide‐mediated hyporeactivity to noradrenaline precedes the induction of nitric oxide synthase in endotoxin shock

C. Thiemermann, J. Vane, C. Szabó, 1993, British journal of pharmacology.

Nitric oxide, bacteria, and host defense in sepsis: who needs what?

C. Thiemermann, P. Radermacher, M. Matějovič, 2004, Shock.

Role of Metabolic Endotoxemia in Systemic Inflammation and Potential Interventions

C. Thiemermann, Shireen Mohammad, S. Mohammad, 2021, Frontiers in Immunology.

Anti-inflammatory properties of enamel matrix derivative in human blood.

S. Foster, C. Thiemermann, A. Aasen, 2006, Journal of periodontal research.

The Septic Heart: Current Understanding of Molecular Mechanisms and Clinical Implications

C. Thiemermann, D. Reuter, M. Derwall, 2019, Chest.

The β-d-Endoglucuronidase Heparanase Is a Danger Molecule That Drives Systemic Inflammation and Correlates with Clinical Course after Open and Endovascular Thoracoabdominal Aortic Aneurysm Repair: Lessons Learnt from Mice and Men

C. Thiemermann, M. Jacobs, G. Marx, 2017, Front. Immunol..

Inhibitors of poly (ADP‐ribose) synthetase reduce renal ischemia‐reperfusion injury in the anesthetized rat in vivo

S. Cuzzocrea, C. Thiemermann, K. Zacharowski, 2000, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

RvE1 Attenuates Polymicrobial Sepsis-Induced Cardiac Dysfunction and Enhances Bacterial Clearance

C. Thiemermann, M. Collino, J. Dalli, 2020, Frontiers in Immunology.

Erythropoietin reduces the development of nonseptic shock induced by zymosan in mice*

N. Patel, E. Mazzon, S. Cuzzocrea, 2006, Critical care medicine.

Pretreatment with EPO reduces the injury and dysfunction caused by ischemia/reperfusion in the mouse kidney in vivo.

N. Patel, S. Cuzzocrea, C. Thiemermann, 2004, Kidney international.

Identification of AnnexinA1 as an Endogenous Regulator of RhoA, and Its Role in the Pathophysiology and Experimental Therapy of Type-2 Diabetes

C. Thiemermann, C. Reutelingsperger, G. Norata, 2019, Front. Immunol..

Modulation of the oxidative stress and inflammatory response by PPAR-gamma agonists in the hippocampus of rats exposed to cerebral ischemia/reperfusion.

C. Thiemermann, M. Gallicchio, R. Mastrocola, 2006, European journal of pharmacology.

Glibenclamide‐induced inhibition of the expression of inducible nitric oxide synthase in cultured macrophages and in the anaesthetized rat

C. Thiemermann, J. Vane, Chin‐Chen Wu, 1995, British journal of pharmacology.

Pioglitazone improves lipid and insulin levels in overweight rats on a high cholesterol and fructose diet by decreasing hepatic inflammation

C. Thiemermann, G. Miglio, M. Aragno, 2010, British journal of pharmacology.

Nonredundant protective properties of FPR2/ALX in polymicrobial murine sepsis

C. Thiemermann, M. Perretti, R. Flower, 2014, Proceedings of the National Academy of Sciences.

Poly(ADP-Ribose) Polymerase and Ischemia-Reperfusion Injury

C. Thiemermann, P. Chatterjee, 2006 .

Effects of tempol, a membrane-permeable radical scavenger, in a gerbil model of brain injury

E. Mazzon, S. Cuzzocrea, C. Thiemermann, 2000, Brain Research.

Trauma alarmins as activators of damage‐induced inflammation

C. Thiemermann, K. Brohi, J. Manson, 2012, The British journal of surgery.

On the selectivity of superoxide dismutase mimetics and its importance in pharmacological studies

Jay L Zweier, Salvatore Cuzzocrea, S. Cuzzocrea, 2003, British journal of pharmacology.

Superoxide dismutase mimetic with catalase activity, EUK-134, attenuates the multiple organ injury and dysfunction caused by endotoxin in the rat.

C. Thiemermann, M. McDonald, P. Chatterjee, 2002, Medical science monitor : international medical journal of experimental and clinical research.

Effect of rosiglitazone and 15-deoxy-Δ12,14-prostaglandin J2 on bleomycin-induced lung injury

E. Mazzon, S. Cuzzocrea, C. Thiemermann, 2005, European Respiratory Journal.

Erythropoietin attenuates acute kidney dysfunction in murine experimental sepsis by activation of the β-common receptor.

J. Kieswich, N. Patel, C. Thiemermann, 2013, Kidney international.

Delayed Administration of Pyroglutamate Helix B Surface Peptide (pHBSP), a Novel Nonerythropoietic Analog of Erythropoietin, Attenuates Acute Kidney Injury

N. Patel, C. Thiemermann, M. Yaqoob, 2012, Molecular medicine.

Nonerythropoietic, tissue-protective peptides derived from the tertiary structure of erythropoietin

Michael A. Yamin, N. Patel, C. Thiemermann, 2008, Proceedings of the National Academy of Sciences.

Pharmacological preconditioning with erythropoietin attenuates the organ injury and dysfunction induced in a rat model of hemorrhagic shock

N. Patel, C. Thiemermann, M. Collino, 2012, Disease Models & Mechanisms.

Beneficial effects of erythropoietin in preclinical models of shock and organ failure

C. Thiemermann, 2007, Critical care.

Recombinant human erythropoietin protects the liver from hepatic ischemia‐reperfusion injury in the rat

C. Thiemermann, M. Yaqoob, B. Sepodes, 2006, Transplant international : official journal of the European Society for Organ Transplantation.

Uremia causes dysbiosis-mediated periodontal disease

A. Boyde, J. Kieswich, C. Thiemermann, 2021 .

Peptidoglycan of Staphylococcus aureus causes inflammation and organ injury in the rat*

S. Foster, C. Thiemermann, A. Aasen, 2004, Critical care medicine.

Aminoguanidine attenuates the delayed circulatory failure and improves survival in rodent models of endotoxic shock

Csaba Szabó, C. Thiemermann, J. Vane, 1995, British journal of pharmacology.

Reduction of renal ischemia-reperfusion injury in 5-lipoxygenase knockout mice and by the 5-lipoxygenase inhibitor zileuton.

N. Patel, S. Cuzzocrea, C. Thiemermann, 2004, Molecular pharmacology.

Bone marrow mononuclear cells reduce myocardial reperfusion injury by activating the PI3K/Akt survival pathway.

P. Munroe, M. Lythgoe, C. Thiemermann, 2010, Atherosclerosis.

ACTIVATION OF PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR-&bgr;/&dgr; ATTENUATES MYOCARDIAL ISCHEMIA/REPERFUSION INJURY IN THE RAT

C. Thiemermann, M. Collino, R. Fantozzi, 2010, Shock.

Protective role of peroxisome proliferator-activated receptor-β/δ in septic shock.

N. Patel, C. Thiemermann, M. Yaqoob, 2010, American journal of respiratory and critical care medicine.

GLYCOGEN SYNTHASE KINASE 3&bgr; INHIBITION REDUCES THE DEVELOPMENT OF NONSEPTIC SHOCK INDUCED BY ZYMOSAN IN MICE

E. Mazzon, S. Cuzzocrea, C. Thiemermann, 2006, Shock.

Inhibition of Induction or Activity of Nitric Oxide Synthase: Novel Approaches for the Therapy of Circulatory Shock

C. Thiemermann, 1995 .

The role of the L-arginine: nitric oxide pathway in circulatory shock.

C. Thiemermann, Christoph Thiemermann, C. Thiemermann, 1994, Advances in pharmacology.

The cell wall components peptidoglycan and lipoteichoic acid from Staphylococcus aureus act in synergy to cause shock and multiple organ failure.

C. Thiemermann, J. Vane, S. D. de Kimpe, 1995, Proceedings of the National Academy of Sciences of the United States of America.

Nifedipine inhibits the induction of nitric oxide synthase by bacterial lipopolysaccharide.

C. Thiemermann, J. Vane, C. Szabó, 1993, The Journal of pharmacology and experimental therapeutics.

What's New In shock , October 2006?

C. Thiemermann, 2006 .

Peroxisome proliferator-activated receptor-γ antagonists GW9662 and T0070907 reduce the protective effects of lipopolysaccharide preconditioning against organ failure caused by endotoxemia*

C. Thiemermann, M. Collin, O. Murch, 2006, Critical care medicine.

The multiple organ dysfunction syndrome caused by endotoxin in the rat: attenuation of liver dysfunction by inhibitors of nitric oxide synthase

C. Thiemermann, J. Vane, H. Ruetten, 1995, British journal of pharmacology.

Vascular hyporeactivity to vasoconstrictor agents and hemodynamic decompensation in hemorrhagic shock is mediated by nitric oxide.

C. Thiemermann, J. Vane, J. Mitchell, 1993, Proceedings of the National Academy of Sciences of the United States of America.

Role of Induced Nitric Oxide in the Initiation of the Inflammatory Response After Postischemic Injury

E. Mazzon, S. Cuzzocrea, C. Thiemermann, 2002, Shock.

Nitrite-derived nitric oxide protects the rat kidney against ischemia/reperfusion injury in vivo: role for xanthine oxidoreductase.

N. Patel, E. Mazzon, S. Cuzzocrea, 2007, Journal of the American Society of Nephrology : JASN.

Tempol, a membrane-permeable radical scavenger, reduces oxidant stress-mediated renal dysfunction and injury in the rat.

S. Cuzzocrea, C. Thiemermann, K. Zacharowski, 2000, Kidney international.

The involvement of endothelium‐derived relaxing factor in the regulation of renal cortical blood flow in the rat

C. Thiemermann, J. Vane, C. Walder, 1991, British journal of pharmacology.

High density lipoproteins reduce organ injury and organ dysfunction in a rat model of hemorrhagic shock

S. Cuzzocrea, C. Thiemermann, M. McDonald, 2001, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Rosiglitazone, a ligand of the peroxisome proliferator-activated receptor-gamma, reduces acute pancreatitis induced by cerulein

N. Patel, S. Cuzzocrea, C. Thiemermann, 2004, Intensive Care Medicine.

Attenuation of endotoxin‐induced multiple organ dysfunction by 1‐amino‐2‐hydroxy‐guanidine, a potent inhibitor of inducible nitric oxide synthase

C. Thiemermann, H. Ruetten, G. Southan, 1996, British journal of pharmacology.

Agonists of Peroxisome-Proliferator Activated Receptor-Gamma Reduce Renal Ischemia/Reperfusion Injury

N. Patel, S. Cuzzocrea, C. Thiemermann, 2003, American Journal of Nephrology.

Effect of selective blockade of endothelin ETB receptors on the liver dysfunction and injury caused by endotoxaemia in the rat

C. Thiemermann, H. Ruetten, 1996, British journal of pharmacology.

Scavenging Circulating Mitochondrial DNA as a Potential Therapeutic Option for Multiple Organ Dysfunction in Trauma Hemorrhage

C. Thiemermann, K. Brohi, C. Hauser, 2018, Front. Immunol..

Role of inducible nitric oxide synthase in the reduced responsiveness of the myocardium to catecholamines in a hyperdynamic, murine model of septic shock*

C. Thiemermann, M. Georgieff, P. Radermacher, 2006, Critical care medicine.

What's New In shock , June 2007

C. Thiemermann, 2007 .

Inhibition of Macrophage Migration Inhibitory Factor Activity Attenuates Haemorrhagic Shock-Induced Multiple Organ Dysfunction in Rats

C. Thiemermann, I. Marzi, B. Relja, 2022, Frontiers in Immunology.

Novel Synthetic, Host-defense Peptide Protects Against Organ Injury/Dysfunction in a Rat Model of Severe Hemorrhagic Shock

C. Thiemermann, K. Brandenburg, T. Gutsmann, 2017, Annals of surgery.

ERYTHROPOIETIN ATTENUATES THE TISSUE INJURY ASSOCIATED WITH HEMORRHAGIC SHOCK AND MYOCARDIAL ISCHEMIA

N. Patel, C. Thiemermann, M. Yaqoob, 2004, Shock.

Peptidoglycan and Lipoteichoic Acid in Gram-Positive Bacterial Sepsis: Receptors, Signal Transduction, Biological Effects, and Synergism

S. Foster, C. Thiemermann, A. Aasen, 2003, Shock.

What's New In shock , September 2006?

C. Thiemermann, 2006 .

Inhibition of endogenous hydrogen sulfide formation reduces the organ injury caused by endotoxemia

C. Thiemermann, P. Moore, M. Collin, 2005, British journal of pharmacology.

Interleukin-1 contributes to the induction of nitric oxide synthase by endotoxin in vivo.

C. Thiemermann, J. Vane, C. Szabó, 1993, European journal of pharmacology.

Regulation of the expression of the inducible isoform of nitric oxide synthase.

C. Thiemermann, C. Szabó, Csaba Szabó, 1995, Advances in pharmacology.

murine models of sepsis sensitive and clinically relevant prognostic marker in Quantification of microcirculatory blood flow: a

C. Thiemermann, D. Treacher, A. Starr, 2015 .

Calpain inhibitor I reduces the activation of nuclear factor-k B and organ injury / dysfunction in hemorrhagic shock

S. Harwood, S. Cuzzocrea, C. Thiemermann, 2000 .

Activation of soluble guanylyl cyclase by a factor other than nitric oxide or carbon monoxide contributes to the vascular hyporeactivity to vasoconstrictor agents in the aorta of rats treated with endotoxin.

C. Thiemermann, J. Vane, C. Szabó, 1994, Biochemical and biophysical research communications.

Pharmacological Inhibition of FAK-Pyk2 Pathway Protects Against Organ Damage and Prolongs the Survival of Septic Mice

C. Thiemermann, C. Cifani, R. Mastrocola, 2022, Frontiers in Immunology.

Refinement of Animal Models of Sepsis and Septic Shock

C. Thiemermann, S. Jackson, P. Hawkins, 2015, Shock.

The hidden role of NLRP3 inflammasome in obesity‐related COVID‐19 exacerbations: Lessons for drug repurposing

C. Thiemermann, M. Collino, V. Brancaleone, 2020, British journal of pharmacology.

Bruton’s tyrosine kinase inhibition attenuates disease progression by reducing renal immune cell invasion in mice with hemolytic-uremic syndrome

F. Gunzer, C. Thiemermann, C. Daniel, 2023, Frontiers in Immunology.

X-Linked Immunodeficient Mice With No Functional Bruton's Tyrosine Kinase Are Protected From Sepsis-Induced Multiple Organ Failure

C. Thiemermann, D. Greaves, S. Coldewey, 2020, Frontiers in Immunology.

The challenge of translating ischemic conditioning from animal models to humans: the role of comorbidities

C. Thiemermann, M. Yaqoob, K. Mccafferty, 2014, Disease Models & Mechanisms.

Impact of metabolic disorders on the structural, functional, and immunological integrity of the blood‐brain barrier: Therapeutic avenues

J. Kieswich, C. Thiemermann, E. Maiorano, 2021, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Targeting the NLRP3 inflammasome to Reduce Diet-induced Metabolic Abnormalities in Mice

C. Thiemermann, J. Cutrin, R. Mastrocola, 2015, Molecular medicine.

Identification of AnnexinA1 as an Endogenous Regulator of RhoA, and Its Role in the Pathophysiology and Experimental Therapy of Type-2 Diabetes

C. Thiemermann, C. Reutelingsperger, G. Norata, 2019, Front. Immunol..

Activation of cytokine synthesis by systemic infusions of lipopolysaccharide and peptidoglycan in a porcine model in vivo and in vitro.

S. Foster, C. Thiemermann, A. Aasen, 2007, Surgical infections.

Development of novel, water-soluble inhibitors of poly (adenosine 5'-diphosphate ribose) synthetase activity for use in shock and ischemia-reperfusion injury.

C. Thiemermann, 2002, Critical care medicine.

Platelet-activating factor contributes to the induction of nitric oxide synthase by bacterial lipopolysaccharide.

C. Thiemermann, J. Vane, C. Szabó, 1993, Circulation research.

Noncleavable poly(ADP-ribose) polymerase-1 regulates the inflammation response in mice.

Z. Herceg, N. Patel, S. Cuzzocrea, 2004, The Journal of clinical investigation.

Advancements in nanomedicines for the detection and treatment of diabetic kidney disease

C. Thiemermann, M. Yaqoob, N. Kamaly, 2022, Biomaterials and biosystems.

Involvement of tyrosine kinase in the induction of cyclo‐oxygenase and nitric oxide synthase by endotoxin in cultured cells

C. Thiemermann, J. Vane, P. Akarasereenont, 1994, British journal of pharmacology.

Rosiglitazone, a ligand of the peroxisome proliferator-activated receptor-gamma, reduces acute inflammation.

N. Patel, S. Cuzzocrea, C. Thiemermann, 2004, European journal of pharmacology.

Erythropoietin reduces the degree of arthritis caused by type II collagen in the mouse.

N. Patel, E. Mazzon, S. Cuzzocrea, 2005, Arthritis and rheumatism.

Oxidative stress and inflammatory response evoked by transient cerebral ischemia/reperfusion: Effects of the PPAR-α agonist WY14643

C. Thiemermann, M. Gallicchio, R. Mastrocola, 2006 .

Beneficial effects of tempol, a membrane-permeable radical scavenger, on the multiple organ failure induced by zymosan in the rat

E. Mazzon, S. Cuzzocrea, C. Thiemermann, 2001, Critical care medicine.

Neutrophil elastase plays a non‐redundant role in remodeling the venular basement membrane and neutrophil diapedesis post‐ischemia/reperfusion injury

N. Patel, S. Cuzzocrea, C. Thiemermann, 2019, The Journal of pathology.

Baricitinib counteracts metaflammation, thus protecting against diet-induced metabolic abnormalities in mice

C. Thiemermann, F. Fava, K. Tuohy, 2020, Molecular metabolism.

Reduction of the multiple organ injury and dysfunction caused by endotoxemia in 5‐lipoxygenase knockout mice and by the 5‐lipoxygenase inhibitor zileuton

N. Patel, S. Cuzzocrea, C. Thiemermann, 2004, Journal of leukocyte biology.

RG100204, A Novel Aquaporin-9 Inhibitor, Reduces Septic Cardiomyopathy and Multiple Organ Failure in Murine Sepsis

C. Thiemermann, G. Calamita, J. Evenäs, 2022, Frontiers in Immunology.

Rosiglitazone and 15‐deoxy‐Δ12,14‐prostaglandin J2, ligands of the peroxisome proliferator‐activated receptor‐γ (PPAR‐γ), reduce ischaemia/reperfusion injury of the gut

N. Patel, S. Cuzzocrea, C. Thiemermann, 2003 .

Rosiglitazone and 15-deoxy-Delta12,14-prostaglandin J2, ligands of the peroxisome proliferator-activated receptor-gamma (PPAR-gamma), reduce ischaemia/reperfusion injury of the gut.

N. Patel, S. Cuzzocrea, C. Thiemermann, 2003, British journal of pharmacology.

Combination immunotherapy which neutralises the effects of TNF alpha and IL-1 beta attenuates the circulatory failure and multiple organ dysfunction caused by endotoxin in the rat.

C. Thiemermann, H. Ruetten, 1997, Journal of physiology and pharmacology : an official journal of the Polish Physiological Society.

Selective activation of E-type prostanoid3-receptors reduces myocardial infarct size

C. Thiemermann, K. Zacharowski, 2000 .

The spice of life: curcumin reduces the mortality associated with experimental sepsis.

C. Thiemermann, 2006, Critical care medicine.

Peptidoglycan primes for LPS-induced release of proinflammatory cytokines in whole human blood.

S. Foster, C. Thiemermann, A. Aasen, 2001, Shock.

Linagliptin Attenuates the Cardiac Dysfunction Associated With Experimental Sepsis in Mice With Pre-existing Type 2 Diabetes by Inhibiting NF-κB

C. Thiemermann, M. Yaqoob, F. Chiazza, 2018, Front. Immunol..

Review: PPARs as new therapeutic targets for the treatment of cerebral ischemia/reperfusion injury

N. Patel, C. Thiemermann, M. Collino, 2008, Therapeutic advances in cardiovascular disease.

Gender Dimorphism of the Cardiac Dysfunction in Murine Sepsis: Signalling Mechanisms and Age-Dependency

N. Patel, C. Thiemermann, S. Coldewey, 2014, PloS one.

Ischaemia and Reperfusion Enhances the Vasoconstrictor Effects of Endothelin-1 in the Isolated Perfused Heart of the Rat

C. Thiemermann, J. Vane, L. Mcmurdo, 1993 .

LIVER X RECEPTOR IS A KEY REGULATOR OF CYTOKINE RELEASE IN HUMAN MONOCYTES

S. Foster, C. Thiemermann, A. Aasen, 2007, Shock.

Generation of endogenous hydrogen sulfide by cystathionine γ-lyase limits renal ischemia/reperfusion injury and dysfunction

J. Kieswich, N. Patel, C. Thiemermann, 2008, Laboratory Investigation.

The tyrosine kinase inhibitor tyrphostin AG126 reduces renal ischemia/reperfusion injury in the rat.

N. Patel, S. Cuzzocrea, C. Thiemermann, 2003, Kidney international.

A Synthetic Peptide Designed to Neutralize Lipopolysaccharides Attenuates Metaflammation and Diet-Induced Metabolic Derangements in Mice

C. Thiemermann, M. Yaqoob, S. Coldewey, 2021, Frontiers in Immunology.

Humane end points in experimental models of septic shock: a must, not a superfluous nightmare for researchers!

C. Thiemermann, P. Radermacher, M. van Griensven, 2013, Shock.

Mechanism of Gram-positive Shock: Identification of Peptidoglycan and Lipoteichoic Acid Moieties Essential in the Induction of Nitric Oxide Synthase, Shock, and Multiple Organ Failure

S. Foster, C. Thiemermann, S. D. de Kimpe, 1998, The Journal of experimental medicine.

INHIBITORS OF NADPH OXIDASE REDUCE THE ORGAN INJURY IN HEMORRHAGIC SHOCK

N. Patel, E. Mazzon, S. Cuzzocrea, 2005, Shock.

Pyrrolidine dithiocarbamate attenuates the development of acute and chronic inflammation

E. Mazzon, S. Cuzzocrea, C. Thiemermann, 2002, British journal of pharmacology.

Minimum Quality Threshold in Pre-Clinical Sepsis Studies (Mqtipss): An International Expert Consensus Initiative for Improvement of Animal Modeling in Sepsis

M. Singer, C. Deutschman, M. Bauer, 2018, Shock.

Potential therapeutic effect of antioxidant therapy in shock and inflammation.

S. Cuzzocrea, C. Thiemermann, D. Salvemini, 2004, Current medicinal chemistry.

Pleiotropic effects of atorvastatin in experimental sepsis: preservation of β1-adrenoreceptor signaling in the heart.

C. Thiemermann, S. Coldewey, 2014, Shock.

Enhanced IL-17 signalling following myocardial ischaemia/reperfusion injury

R. Knight, C. Thiemermann, G. Faggian, 2013, International journal of cardiology.

Endothelium-derived relaxing factor participates in the increased blood flow in response to pentagastrin in the rat stomach mucosa

C. Thiemermann, J. Vane, C. Walder, 1990, Proceedings of the Royal Society of London. Series B: Biological Sciences.

Lipoproteins in inflammation and sepsis. I. Basic science

C. Thiemermann, M. Collin, C. Hinds, 2006, Intensive Care Medicine.

Effects of nitric oxide synthase inhibition combined with nitric oxide inhalation in a porcine model of endotoxin shock.

C. Thiemermann, P. Klemm, P. Martorana, 1995, British journal of pharmacology.

A novel model of reno-cardiac syndrome in the C57BL/ 6 mouse strain

J. Kieswich, C. Thiemermann, M. Yaqoob, 2018, BMC Nephrology.

The Response to the Letter to the Editor Titled: "Is Triple Self-plagiarism "OK" If Only Made Transparent?" by Volker R Jacobs, MD, MBA.

C. Thiemermann, C. Libert, D. Remick, 2019, Shock.

The MEK Inhibitor Trametinib Ameliorates Kidney Fibrosis by Suppressing ERK1/2 and mTORC1 Signaling.

J. Kieswich, S. Harwood, C. Thiemermann, 2018, Journal of the American Society of Nephrology : JASN.

Erythropoietin protects the kidney against the injury and dysfunction caused by ischemia-reperfusion.

D. Allen, J. Kieswich, N. Patel, 2004, Journal of the American Society of Nephrology : JASN.

Endogenously generated arachidonate‐derived ligands for TRPV1 induce cardiac protection in sepsis

C. Thiemermann, A. Ahluwalia, R. Colas, 2018, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Ligands of the peroxisome proliferator‐activated receptors (PPAR‐γ and PPAR‐α) reduce myocardial infarct size

S. Cuzzocrea, C. Thiemermann, Y. Hattori, 2002, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Development and validation of a reinforcement learning algorithm to dynamically optimize mechanical ventilation in critical care

L. Celi, G. Ascheid, C. Thiemermann, 2021, npj Digital Medicine.

Relaxin activates the L-arginine-nitric oxide pathway in vascular smooth muscle cells in culture.

C. Thiemermann, E. Masini, D. Bani, 1998, Hypertension.

FMRF-amide and L-Arg-L-Phe increase blood pressure and heart rate in the anaesthetised rat by central stimulation of the sympathetic nervous system.

C. Thiemermann, J. Vane, M. Hecker, 1991, Biochemical and biophysical research communications.

EFFECTS OF 5‐AMINOISOQUINOLINONE, A WATER‐ SOLUBLE, POTENT INHIBITOR OF THE ACTIVITY OF POLY (ADP‐RIBOSE) POLYMERASE, IN A RODENT MODEL OF LUNG INJURY.: 9

E. Mazzon, S. Cuzzocrea, C. Thiemermann, 2001 .

The Antimalarial Drug Artesunate Attenuates Cardiac Injury in A Rodent Model of Myocardial Infarction.

C. Thiemermann, L. Decosterd, M. Collino, 2018, Shock.

Role of PPAR-δ in the development of zymosan-induced multiple organ failure: an experiment mice study

E. Mazzon, S. Cuzzocrea, C. Thiemermann, 2010, Journal of Inflammation.

Rosiglitazone, a ligand of the peroxisome proliferator-activated receptor-&ggr;, reduces the development of nonseptic shock induced by zymosan in mice*

N. Patel, S. Cuzzocrea, C. Thiemermann, 2004, Critical care medicine.

The Cardioprotective Effects of Preconditioning with Endotoxin, but Not Ischemia, Are Abolished by a Peroxisome Proliferator-Activated Receptor-γ Antagonist

C. Thiemermann, M. McDonald, A. Sivarajah, 2005, Journal of Pharmacology and Experimental Therapeutics.

Activated Protein C Drives the Hyperfibrinolysis of Acute Traumatic Coagulopathy

C. Thiemermann, R. Pearse, M. Cohen, 2017, Anesthesiology.

Role of nitric oxide in the circulatory failure and organ injury in a rodent model of Gram‐positive shock

C. Thiemermann, S. Kimpe, K. Kengatharan, 1996, British journal of pharmacology.

Inhibition of the production of nitric oxide and vasodilator prostaglandins attenuates the cardiovascular response to bacterial endotoxin in adrenalectomized rats

C. Thiemermann, J. Vane, C. Szabó, 1993, Proceedings of the Royal Society of London. Series B: Biological Sciences.

Identification of copper/zinc superoxide dismutase as a novel nitric oxide‐regulated gene in rat glomerular mesangial cells and kidneys of endotoxemic rats

C. Thiemermann, J. Pfeilschifter, K. Zacharowski, 1999, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Pyrrolidine dithiocarbamate attenuates the development of organ failure induced by zymosan in mice

N. Patel, S. Cuzzocrea, C. Thiemermann, 2003, Intensive Care Medicine.

Role of peroxisome proliferator-activated receptor-&ggr; in the protection afforded by 15-deoxy&Dgr;12,14 prostaglandin J2 against the multiple organ failure caused by endotoxin

N. Patel, C. Thiemermann, L. Dugo, 2004, Critical care medicine.

Chemical and biochemical characterization and in vivo safety evaluation of pharmaceuticals in drinking water

C. Thiemermann, H. Mota-Filipe, V. Cardoso, 2016, Environmental toxicology and chemistry.

The induction of cyclo-oxygenase-2 in human pulmonary epithelial cell culture (A549) activated by IL-1beta is inhibited by tyrosine kinase inhibitors.

C. Thiemermann, P. Akarasereenont, 1996, Biochemical and biophysical research communications.

Sex-specific regulation of chemokine Cxcl5/6 controls neutrophil recruitment and tissue injury in acute inflammatory states

N. Patel, C. Thiemermann, D. Gilroy, 2015, Biology of Sex Differences.

Effects of inhibitors of the activity of cyclo‐oxygenase‐2 on the hypotension and multiple organ dysfunction caused by endotoxin: A comparison with dexamethasone

C. Thiemermann, A. Olbrich, G. Wray, 1998, British journal of pharmacology.

Inhibition of Bruton’s Tyrosine Kinase Activity Attenuates Hemorrhagic Shock-Induced Multiple Organ Dysfunction in Rats

C. Thiemermann, S. Coldewey, R. Sordi, 2021, Annals of surgery.

Inhibition of Bruton’s tyrosine kinase activity attenuates trauma-induced multiple organ dysfunction in rats

C. Thiemermann, S. Coldewey, R. Sordi, 2021, bioRxiv.

5-Aminoisoquinolinone reduces colon injury by experimental colitis

N. Patel, E. Mazzon, S. Cuzzocrea, 2004, Naunyn-Schmiedeberg's Archives of Pharmacology.

Beneficial effects of PPAR-γ ligands in ischemia–reperfusion injury, inflammation and shock

C. Thiemermann, A. Sivarajah, M. Abdelrahman, 2005 .

Organ Injury and Cytokine Release Caused by Peptidoglycan Are Dependent on the Structural Integrity of the Glycan Chain

S. Foster, C. Thiemermann, A. Aasen, 2004, Infection and Immunity.

Importance of Cell Wall Components of Gram-Positive Bacteria in Gram-Positive Septic Shock

C. Thiemermann, K. Kengatharan, 1997 .

Modification of metabolism of transplantable and spontaneous murine tumors by the nitric oxide synthase inhibitor, nitro-L-arginine.

C. Thiemermann, J. Vane, G. Adams, 1994, International journal of radiation oncology, biology, physics.

Resolvin D1 Attenuates the Organ Injury Associated With Experimental Hemorrhagic Shock

C. Thiemermann, G. Migliaretti, K. Brohi, 2019, Annals of surgery.

Minimum Quality Threshold in Pre-Clinical Sepsis Studies (MQTiPSS): an international expert consensus initiative for improvement of animal modeling in sepsis

M. Singer, C. Deutschman, M. Bauer, 2018, Infection.

Receptor-selective vasopressin analogs: a new push for "decatecholaminization"?

C. Thiemermann, P. Radermacher, 2013, Shock.

Endothelial cells metabolize NG-monomethyl-L-arginine to L-citrulline and subsequently to L-arginine.

C. Thiemermann, J. Vane, M. Hecker, 1990, Biochemical and biophysical research communications.

Selenium and Niacin for Sepsis Therapy: The Sum Is Greater Than Its Parts.

C. Thiemermann, Jianmin Chen, 2016, Critical Care Medicine.

Inhibition of IκB kinase reduces the multiple organ dysfunction caused by sepsis in the mouse

N. Patel, C. Thiemermann, S. Coldewey, 2013, Disease Models & Mechanisms.

Sepsis-3 on the Block: What Does It Mean for Preclinical Sepsis Modeling?

C. Thiemermann, D. Remick, M. Osuchowski, 2017, Shock.

Induction of Nitric Oxide and Tetrahydrobiopterin Synthesis by Lipoteichoic Acid from Staphylococcus aureus in VascularSmooth Muscle Cells

C. Thiemermann, Y. Hattori, K. Kasai, 1998, Journal of Vascular Research.

Beneficial effects of PPAR-gamma ligands in ischemia-reperfusion injury, inflammation and shock.

C. Thiemermann, A. Sivarajah, M. Abdelrahman, 2005, Cardiovascular research.

A cell wall component from pathogenic and non-pathogenic gram-positive bacteria (peptidoglycan) synergises with endotoxin to cause the release of tumour necrosis factor-alpha, nitric oxide production, shock, and multiple organ injury/dysfunction in the rat.

S. Foster, C. Thiemermann, C. Hinds, 2001, Shock.

PEPTIDOGLYCAN OF S. AUREUS CAUSES INCREASED LEVELS OF MATRIX METALLOPROTEINASES IN THE RAT

S. Foster, C. Thiemermann, A. Aasen, 2004, Shock.

Relative Adrenal Insufficiency in Cardiogenic Shock: Is There a Need for Action?

J. Briegel, C. Thiemermann, P. Radermacher, 2017, Shock.

NG‐hydroxy‐L‐arginine prevents the haemodynamic effects of nitric oxide synthesis inhibition in the anaesthetized rat

C. Thiemermann, J. Vane, C. Walder, 1992, British Journal of Pharmacology.

Dihydropyridine antagonists and agonists of calcium channels inhibit the induction of nitric oxide synthase by endotoxin in cultured macrophages.

C. Thiemermann, J. Vane, C. Szabó, 1993, Biochemical and biophysical research communications.

Reduction in the evolution of murine type II collagen-induced arthritis by treatment with rosiglitazone, a ligand of the peroxisome proliferator-activated receptor gamma.

N. Patel, E. Mazzon, S. Cuzzocrea, 2003, Arthritis and rheumatism.

Biological control and inhibition of induction of nitric oxide synthase.

C. Thiemermann, C. Wu, 1996, Methods in enzymology.

Tempol, a membrane-permeable radical scavenger, reduces dinitrobenzene sulfonic acid-induced colitis.

E. Mazzon, S. Cuzzocrea, C. Thiemermann, 2000, European journal of pharmacology.

Peroxisome Proliferator-Activated Receptor-α Contributes to the Resolution of Inflammation after Renal Ischemia/Reperfusion Injury

N. Patel, E. Mazzon, S. Cuzzocrea, 2009, Journal of Pharmacology and Experimental Therapeutics.

What's new in shock, May 2007?

C. Thiemermann, 2007, Shock.

A non‐erythropoietic peptide derivative of erythropoietin decreases susceptibility to diet‐induced insulin resistance in mice

C. Thiemermann, M. Minetto, R. Mastrocola, 2014, British journal of pharmacology.

For Peer Review A nonerythropoietic peptide derivative of erythropoietin decreases susceptibility to diet-induced insulin resistance in mice.

C. Thiemermann, M. Aragno, E. Benetti, 2014 .

A nonerythropoietic peptide derivative of erythropoietin decreases susceptibility to diet-induced insulin resistance in mice

C. Thiemermann, M. Minetto, R. Mastrocola, 2022 .

Beneficial effects of GW274150 treatment on the development of experimental colitis induced by dinitrobenzene sulfonic acid.

N. Patel, E. Mazzon, S. Cuzzocrea, 2005, European journal of pharmacology.

Inhibition of the induction of nitric oxide synthase by spermine is modulated by aldehyde dehydrogenase.

C. Thiemermann, C. Szabó, G. Southan, 1994, Biochemical and biophysical research communications.

The oDGal Mouse: A Novel, Physiologically Relevant Rodent Model of Sporadic Alzheimer’s Disease

P. Maycox, C. Thiemermann, Stuart Maudsley, 2023, International journal of molecular sciences.

Batch effect exerts a bigger influence on the rat urinary metabolome and gut microbiota than uraemia: a cautionary tale

J. Kieswich, C. Thiemermann, L. Hoyles, 2019, Microbiome.

Ribonuclease 1 attenuates septic cardiomyopathy and cardiac apoptosis in a murine model of polymicrobial sepsis.

C. Thiemermann, G. Müller-Newen, S. Coldewey, 2020, JCI insight.

Regional Vascular Resistance and Haemodynamics in the Spontaneously Hypertensive Rat: The Effects of Bradykinin

C. Thiemermann, J. Vane, G. Thomas, 1990, Journal of cardiovascular pharmacology.

What's new in Shock, April 2008?

C. Thiemermann, 2008, Shock.

Oxygen in the Heart: How Much is too Much?

C. Thiemermann, P. Radermacher, M. Huber-Lang, 2017, Shock.

Morphological Analysis of the Iloprost Effects on Reperfused Ischemic Myocardium

C. Thiemermann, K. Schrör, G. Arnold, 1985 .

, in Culture Nitric Oxide Pathway in Vascular Smooth Muscle Cells − Relaxin Activates the l-Arginine

C. Thiemermann, E. Masini, D. Bani, 1998 .

Inhibition of glycogen synthase kinase-3beta attenuates the development of carrageenan-induced lung injury in mice.

E. Mazzon, S. Cuzzocrea, C. Thiemermann, 2006, British journal of pharmacology.

Endogenous ligands of PPAR-γ reduce the liver injury in haemorrhagic shock

C. Thiemermann, M. Collin, M. Abdelrahman, 2004 .

Endogenous ligands of PPAR-gamma reduce the liver injury in haemorrhagic shock.

C. Thiemermann, M. Collin, M. Abdelrahman, 2004, European journal of pharmacology.

The obesity paradox revisited: does increased body mass protect against circulatory shock?

C. Thiemermann, U. Knippschild, P. Radermacher, 2014, Shock.

Norepinephrine, the Intensivist's Swiss Army Knife for Circulatory Shock?

C. Thiemermann, P. Asfar, P. Radermacher, 2016, Shock.

Correction to: Minimum Quality Threshold in Pre-Clinical Sepsis Studies (MQTiPSS): an international expert consensus initiative for improvement of animal modeling in sepsis

M. Singer, C. Deutschman, M. Bauer, 2018, Infection.

Incomplete inhibition of the pressor effects of endothelin‐1 and related peptides in the anaesthetized rat with BQ‐123 provides evidence for more than one vasoconstrictor receptor

C. Thiemermann, J. Vane, R. Corder, 1993, British journal of pharmacology.

Inhibition of the release of endothelium‐derived relaxing factor in vitro and in vivo by dipeptides containing NG‐nitro‐l‐arginine

Jane A. Mitchell, C. Thiemermann, J. Vane, 1991, British journal of pharmacology.

Glycogen synthase kinase-3 beta inhibition reduces secondary damage in experimental spinal cord trauma.

E. Mazzon, S. Cuzzocrea, C. Thiemermann, 2006, The Journal of pharmacology and experimental therapeutics.

Liver X receptor protects against liver injury in sepsis caused by rodent cecal ligation and puncture.

I. Chaudry, C. Thiemermann, J. Gustafsson, 2011, Surgical infections.

Endothelin inhibits ex vivo platelet aggregation in the rabbit.

C. Thiemermann, J. Vane, P. Lidbury, 1988, European journal of pharmacology.

Inhaled CO: Deadly gas or novel therapeutic?

C. Thiemermann, 2001, Nature Medicine.

Poly (ADP-Ribose) Polymerase Inhibitors and Acute Renal Failure

C. Thiemermann, P. Chatterjee, 2002 .

Support of renal blood flow after ischaemic‐reperfusion injury by endogenous formation of nitric oxide and of cyclo‐oxygenase vasodilator metabolites

C. Thiemermann, J. Vane, J. Cristol, 1993, British journal of pharmacology.

Hydrogen sulfide, neurogenic inflammation, and cardioprotection: a tale of rotten eggs and vanilloid receptors.

C. Thiemermann, A. Kapoor, 2010, Critical Care Medicine.

Comparison of the thromboxane synthetase inhibitor dazoxiben and the prostacyclin mimetic iloprost in an animal model of acute ischaemia and reperfusion.

C. Thiemermann, K. Schrör, 1984, Biomedica biochimica acta.

Protein tyrosine kinase inhibitors as novel therapeutics for systemic inflammation, shock, and organ injury.

C. Thiemermann, 2003, Critical care medicine.

Lipid A and the lipid A analogue anti-tumour compound ONO-4007 induce nitric oxide synthase in vitro and in vivo.

C. Thiemermann, J. Vane, Y. Hattori, 1995, European journal of pharmacology.

12‐Lipoxygenase‐derived eicosanoids protect against myocardial ischemia/reperfusion injury via activation of neuronal TRPV1

C. Thiemermann, A. Ahluwalia, M. McDonald, 2007, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Vasoconstriction in the rat kidney induced by endothelin-1 is blocked by PD 145065.

C. Thiemermann, J. Vane, T. Warner, 1993, Journal of cardiovascular pharmacology.

Bruton's Tyrosine Kinase Inhibition Attenuates the Cardiac Dysfunction Caused by Cecal Ligation and Puncture in Mice

C. Thiemermann, S. Coldewey, F. Chiazza, 2019, Front. Immunol..

Characterisation of cystathionine gamma-lyase/hydrogen sulphide pathway in ischaemia/reperfusion injury of the mouse kidney: an in vivo study.

N. Patel, C. Thiemermann, M. Perretti, 2009, European journal of pharmacology.

What's new in shock, March 2008.

C. Thiemermann, 2008, Shock.

The inhibition of Macrophage Migration Inhibitory Factor by ISO-1 attenuates trauma-induced multiorgan dysfunction in rats

C. Thiemermann, I. Marzi, B. Relja, 2021, medRxiv.

Endothelin- inhibits platelet aggregation invivo: a study with Hlindium-labelled platelets

C. Thiemermann, 1990 .

Induction of cytokine production in human T cells and monocytes by highly purified lipoteichoic acid: involvement of Toll-like receptors and CD14.

C. Thiemermann, T. Hartung, D. Golenbock, 2002, Medical science monitor : international medical journal of experimental and clinical research.

Modification of energy metabolism and radiation response of a murine tumour by changes in nitric oxide availability.

C. Thiemermann, J. Vane, G. Adams, 1993, Biochemical and biophysical research communications.

Retraction notice to “Enhanced IL-17 signalling following myocardial ischaemia/reperfusion injury” [Int. J. Cardiol. 163 (2013) 326–334]

R. Knight, C. Thiemermann, G. Faggian, 2019, International journal of cardiology.

Upregulation of ICAM-1 expression on J774.2 macrophages by endotoxin involves activation of NF-kappaB but not protein tyrosine kinase: comparison to induction of iNOS.

C. Thiemermann, M. Perretti, H. Ruetten, 1999, Mediators of inflammation.

Safety and efficacy of artesunate treatment in severely injured patients with traumatic hemorrhage. The TOP-ART randomized clinical trial

C. Thiemermann, A. Brentnall, J. Tarning, 2023, Intensive Care Medicine.

Corrigendum to “Oxidative stress and inflammatory response evoked by transient cerebral ischemia/reperfusion: Effects of the PPAR-α agonist WY14643” [Free Radic. Biol. Med. 41: 579–589; 2006]

C. Thiemermann, M. Gallicchio, R. Mastrocola, 2006 .

Oxidative stress and inflammatory response evoked by transient cerebral ischemia/reperfusion: effects of the PPAR-alpha agonist WY14643.

C. Thiemermann, M. Gallicchio, R. Mastrocola, 2006, Free radical biology & medicine.

Niacin as a novel therapy for septic shock?

C. Thiemermann, A. Kapoor, 2011, Critical Care Medicine.

Inducible nitric oxide synthase-deficient mice exhibit resistance to the acute pancreatitis induced by cerulein.

E. Mazzon, S. Cuzzocrea, C. Thiemermann, 2001 .

Ligands of the peroxisome proliferator-activated receptor-gamma and heart failure.

C. Thiemermann, 2004, British journal of pharmacology.

Acute Treatment With Bone Marrow–Derived Mononuclear Cells Attenuates the Organ Injury/Dysfunction Induced by Hemorrhagic Shock in the Rat

N. Patel, C. Thiemermann, E. Benetti, 2012, Shock.

IκB Kinase Inhibitor Attenuates Sepsis-Induced Cardiac Dysfunction in CKD.

J. Kieswich, N. Patel, C. Thiemermann, 2017, Journal of the American Society of Nephrology : JASN.

SEPSIS-3 On the Block: What Does It Mean for Pre-Clinical Sepsis Modeling?

C. Thiemermann, D. Remick, M. Osuchowski, 2017, Shock.

Minimum Quality Threshold in Pre-Clinical Sepsis Studies (Mqtipss): An International Expert Consensus Initiative for Improvement of Animal Modeling in Sepsis

M. Singer, C. Deutschman, C. Coopersmith, 2018, Shock.

Minimum quality threshold in pre-clinical sepsis studies (MQTiPSS): an international expert consensus initiative for improvement of animal modeling in sepsis

M. Singer, C. Deutschman, M. Bauer, 2018, Intensive Care Medicine Experimental.

Changes in energy metabolism and X-ray sensitivity in murine tumours by the nitric oxide donor SIN-1.

C. Thiemermann, J. Vane, G. Adams, 1996, The British journal of cancer. Supplement.

TREATMENT WITH AMINOETHYLISOTHIOUREA A SELECTIVE INHIBITOR OF THE INDUCIBLE ISOFORM OF NITRIC OXIDE SYNTHASE IMPROVES LIVER CIRCULATION AND OXYGEN METABOLISM IN ENDOTOXEMIA.: 4

C. Thiemermann, O. Smiseth, A. Aasen, 1996 .

Catecholamines and the septic heart: opening Pandora's box?

C. Thiemermann, P. Radermacher, M. Huber-Lang, 2013, Shock.

Themultiple organ dysfunction syndrome caused byendotoxin in therat: attenuation ofliver dysfunction byinhibitors ofnitric oxide synthase

C. Thiemermann, H. Ruetten, Chin‐Chen Wu, 1995 .

Targeting CCR2: a novel therapeutic strategy for septic shock?

C. Thiemermann, A. Kapoor, 2011, American Journal of Respiratory and Critical Care Medicine.

Glycogen synthase kinase-3β inhibition attenuates the development of ischaemia/reperfusion injury of the gut

E. Mazzon, S. Cuzzocrea, C. Thiemermann, 2007, Intensive Care Medicine.

5-Aminoisoquinolinone reduces colon injury by experimental colitis

N. Patel, E. Mazzon, S. Cuzzocrea, 2004, Naunyn-Schmiedeberg's Archives of Pharmacology.

Calpain inhibitor I reduces the activation of nuclear factor‐κΒ and organ injury/dysfunction in hemorrhagic shock

S. Harwood, S. Cuzzocrea, C. Thiemermann, 2001, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Upregulation of ICAM-1 expression on J774.2 macrophages by endotoxin involves activation of NF-kappaB but not protein tyrosine kinase: comparison to induction of iNOS.

C. Thiemermann, M. Perretti, H. Ruetten, 1999, Mediators of inflammation.

What's new in Shock, September 2008?

C. Thiemermann, 2008, Shock.

Lipoteichoic acid from Staphylococcus aureus reduces renal ischemia/reperfusion injury.

S. Cuzzocrea, C. Thiemermann, K. Zacharowski, 2002, Kidney international.

What's new in shock, March 2008.

C. Thiemermann, 2008, Shock.

C. Thiemermann, J. Gustafsson, F. Reinholt, 2009, Shock.

Role of PPAR-δ in the development of zymosan-induced multiple organ failure: an experiment mice study

E. Mazzon, S. Cuzzocrea, C. Thiemermann, 2010, Journal of Inflammation.

The obesity paradox revisited: does increased body mass protect against circulatory shock?