B. Davidson

B. Davidson, J. Kern, S. Graham, 1998, Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.

Adenovirus-mediated gene transfer is augmented in basilar and carotid arteries of heritable hyperlipidemic rabbits.

B. Davidson, D. Heistad, F. Faraci, 1999, Stroke.

Heritable Hyperlipidemic Rabbits Adenovirus-Mediated Gene Transfer Is Augmented in Basilar and Carotid Arteries of

B. Davidson, D. Heistad, F. Faraci, 1998 .

RNA Interference: A Tool for Querying Nervous System Function and an Emerging Therapy

B. Davidson, R. Boudreau, Ryan L. Boudreau, 2007, Neuron.

Vectors Cells by Feline Immunodeficiency Virus Transduction of Dividing and Nondividing Minimum Requirements for Efficient

K. Campbell, B. Davidson, L. E. Lim, 2013 .

Minimum Requirements for Efficient Transduction of Dividing and Nondividing Cells by Feline Immunodeficiency Virus Vectors

K. Campbell, B. Davidson, L. E. Lim, 1999, Journal of Virology.

The transcription factor ATF4 promotes skeletal myofiber atrophy during fasting.

B. Davidson, M. Suneja, Scott M. Ebert, 2010, Molecular endocrinology.

CLN3 Loss Disturbs Membrane Microdomain Properties and Protein Transport in Brain Endothelial Cells

B. Davidson, K. Sandhoff, L. Tecedor, 2013, Journal of Neuroscience.

Immortalized striatal precursor neurons from Huntington's disease patient-derived iPS cells as a platform for target identification and screening for experimental therapeutics.

Amanda J. Kedaigle, E. Fraenkel, R. Cole, 2021, Human molecular genetics.

Cis-acting single nucleotide polymorphisms alter MicroRNA-mediated regulation of human brain-expressed transcripts

Ryan M Spengler, B. Davidson, S. Ramachandran, 2016, Human molecular genetics.

Rhes suppression enhances disease phenotypes in Huntington's disease mice.

P. Nopoulos, D. Thedens, B. Davidson, 2014, Journal of Huntington's disease.

Transduction of neurons lining the cerebral external capsules in mice with feline immunodeficiency virus based vectors

B. Davidson, S. Hughes, J. Alisky, 2003, Neuroscience Letters.

Expression of human interleukin-1 receptor antagonist in mouse lungs using a recombinant adenovirus: effects on vector-induced inflammation.

R. D. McCoy, B. Davidson, G. Huffnagle, 1995, Gene therapy.

Interleukin-10 modulates the severity of hypersensitivity pneumonitis in mice.

B. Davidson, G. Gudmundsson, G. Hunninghake, 1998, American journal of respiratory cell and molecular biology.

Selective Gene Transfer to Key Cardiovascular Regions of the Brain: Comparison of Two Viral Vector Systems

B. Davidson, M. Cassell, P. Staber, 2002, Hypertension.

Phenotype correction in retinal pigment epithelium in murine mucopolysaccharidosis VII by adenovirus-mediated gene transfer.

B. Davidson, T. Li, Tiansen Li, 1995, Proceedings of the National Academy of Sciences of the United States of America.

The transcription factor ATF4 promotes skeletal myofiber atrophy during fasting.

B. Davidson, M. Suneja, Scott M. Ebert, 2010, Molecular endocrinology.

AAV gene transfer delays disease onset in a TPP1-deficient canine model of the late infantile form of Batten disease

B. Davidson, E. Lysenko, L. Tecedor, 2015, Science Translational Medicine.

Intraventricular enzyme replacement improves disease phenotypes in a mouse model of late infantile neuronal ceroid lipofuscinosis.

B. Davidson, J. Cooper, Seng H. Cheng, 2008, Molecular therapy : the journal of the American Society of Gene Therapy.

Extensive beta-glucuronidase activity in murine central nervous system after adenovirus-mediated gene transfer to brain.

B. Davidson, C. Stein, C. Stein, 1998, Human gene therapy.

Adenovirus-mediated gene transfer to normal and atherosclerotic arteries. A novel approach.

B. Davidson, D. Heistad, H. Ooboshi, 1995, Arteriosclerosis, thrombosis, and vascular biology.

4. In Vitro and In Vivo Analysis of Feline Immunodeficiency Virus-Based Lentiviral Vector Integration|[ast]|

T. Casavant, T. Scheetz, B. Davidson, 2004 .

Adenovirus-mediated gene transfer in vivo to cerebral blood vessels and perivascular tissue.

B. Davidson, D. Heistad, H. Ooboshi, 1995, Circulation research.

Inhibition of interleukin-1-induced effects in synoviocytes transduced with the human IL-1 receptor antagonist cDNA using an adenoviral vector.

B. Davidson, J. M. Latta, B. Roessler, 1995, Human gene therapy.

Long‐term reversal of hypercholesterolemia in low density lipoprotein receptor (LDLR)‐deficient mice by adenovirus‐mediated LDLR gene transfer combined with CD154 blockade

I. Martins, B. Davidson, C. Stein, 2000, The journal of gene medicine.

Intracranial Delivery of CLN2 Reduces Brain Pathology in a Mouse Model of Classical Late Infantile Neuronal Ceroid Lipofuscinosis

R. Crystal, Q. Mao, B. Davidson, 2006, The Journal of Neuroscience.

Efficient delivery of RNA interference oligonucleotides to polarized airway epithelia in vitro.

Ashley M. Jacobi, B. Davidson, A. Jacobi, 2013, American journal of physiology. Lung cellular and molecular physiology.

Attenuation of Ischemic Inflammatory Response in Mouse Brain Using an Adenoviral Vector to Induce Overexpression of Interleukin-1 Receptor Antagonist

B. Davidson, Guo-Yuan Yang, A. Betz, 1998, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Reproducible and efficient murine CNS gene delivery using a microprocessor-controlled injector

B. Davidson, M. Halterman, H. Federoff, 1998, Journal of Neuroscience Methods.

Adenoviral-Mediated Gene Transfer: Potential Therapeutic Applications

B. Davidson, B. Roessler, 1995 .

Vascular Cell Adhesion Molecule-1 Augments Adenovirus-Mediated Gene Transfer

M. Cybulsky, B. Davidson, D. Heistad, 2001, Arteriosclerosis, thrombosis, and vascular biology.

Ultrasound-Guided Gene Transfer to Hepatocytes in utero

B. Davidson, R. Williamson, Guoshun Wang, 1998, Fetal Diagnosis and Therapy.

AAV-Mediated Progranulin Delivery to a Mouse Model of Progranulin Deficiency Causes T Cell-Mediated Toxicity.

B. Davidson, A. Chen-Plotkin, E. Lancaster, 2019, Molecular therapy : the journal of the American Society of Gene Therapy.

AAV-mediated progranulin delivery to a mouse model of progranulin deficiency causes T cell-mediated hippocampal degeneration

B. Davidson, A. Chen-Plotkin, E. Lancaster, 2018, bioRxiv.

Huntington’s disease phenotypes are improved via mTORC1 modulation by small molecule therapy

B. Davidson, E. Giaime, E. Saiah, 2022, PloS one.

Use of recombinant adenovirus to transfer the herpes simplex virus thymidine kinase (HSVtk) gene to thoracic neoplasms: an effective in vitro drug sensitization system.

B. Davidson, James M. Wilson, H. Hwang, 1994, Cancer research.

Defining the pathway for Tat-mediated delivery of beta-glucuronidase in cultured cells and MPS VII mice.

W. Sly, Q. Mao, B. Davidson, 2005, Molecular therapy : the journal of the American Society of Gene Therapy.

Augmented adenovirus-mediated gene transfer to atherosclerotic vessels.

B. Davidson, D. Heistad, F. Faraci, 1997, Arteriosclerosis, thrombosis, and vascular biology.

Human-specific microRNA regulation of FOXO1: implications for microRNA recognition element evolution.

Ryan M Spengler, Y. Xing, B. Davidson, 2014, Human molecular genetics.

The Neuronal Ceroid Lipofuscinoses: Clinical Features and Molecular Basis of Disease

B. Davidson, D. Pearce, M. Cabrera-Salazar, 2007 .

Safety and Efficacy of Ex Vivo Donor Lung Adenoviral IL-10 Gene Therapy in a Large Animal Lung Transplant Survival Model.

B. Davidson, S. Keshavjee, T. Waddell, 2017, Human gene therapy.

Gene transfer of calcitonin gene-related peptide to cerebral arteries.

B. Davidson, D. Heistad, F. Faraci, 2000, American journal of physiology. Heart and circulatory physiology.

Adenovirus-mediated gene transfer in vivo to cerebral blood vessels and perivascular tissue in mice.

B. Davidson, D. Heistad, F. Faraci, 1998, Stroke.

Altered vascular function after adenovirus-mediated overexpression of endothelial nitric oxide synthase.

B. Davidson, D. Heistad, F. Faraci, 1997, The American journal of physiology.

Gene transfer to cerebral blood vessels after subarachnoid hemorrhage.

B. Davidson, D. Heistad, H. Ooboshi, 1997, Stroke.

Intrapericardial administration of adenovirus for gene transfer.

B. Davidson, D. Heistad, H. Ooboshi, 1997, The American journal of physiology.

Sialic acid deposition impairs the utility of AAV9, but not peptide-modified AAVs for brain gene therapy in a mouse model of lysosomal storage disease.

B. Davidson, James C. Geoghegan, Y. Chen, 2012, Molecular therapy : the journal of the American Society of Gene Therapy.

Complexes of Adenovirus with Polycationic Polymers and Cationic Lipids Increase the Efficiency of Gene Transfer in Vitro and in Vivo*

B. Davidson, T. Moninger, J. Zabner, 1997, The Journal of Biological Chemistry.

Effects of keratinocyte and hepatocyte growth factor in vivo: implications for retrovirus-mediated gene transfer to liver.

K. Matsumoto, T. Nakamura, B. Davidson, 1998, Human gene therapy.

Increasing epithelial junction permeability enhances gene transfer to airway epithelia In vivo.

B. Davidson, J. Zabner, P. McCray, 2000, American journal of respiratory cell and molecular biology.

SHORT COMMUNICATION Determination of the Mutations Responsible for the Lesch-Nyhan Syndrome in 17 Subjects'

B. Davidson, J. Seegmiller, T. Palella, 1991 .

Haplotyping SNPs for allele-specific gene editing of the expanded huntingtin allele using long-read sequencing

B. Davidson, A. Dürr, Kai Wang, 2022, HGG advances.

Treatment of Experimental Human Mesothelioma Using Adenovirus Transfer of the Herpes Simplex Thymidine Kinase Gene

B. Davidson, H. Hwang, W. Smythe, 1995, Annals of surgery.

Identification of 17 independent mutations responsible for human hypoxanthine-guanine phosphoribosyltransferase (HPRT) deficiency.

B. Davidson, R. Watts, T. Palella, 1991, American journal of human genetics.

Human Coronavirus 229E Infects Polarized Airway Epithelia from the Apical Surface

B. Davidson, S. Perlman, P. McCray, 2000, Journal of Virology.

Antagonistic roles of canonical and alternative RPA in tandem CAG repeat diseases

F. Boisvert, B. Davidson, A. L. Deshmukh, 2022, bioRxiv.

In vivo transfer of a reporter gene to the retina mediated by an adenoviral vector.

B. Davidson, T. Dryja, E. Berson, 1994, Investigative ophthalmology & visual science.

INFLAMMATION INDUCED BY ADENOVIRAL PARTICLES

R. D. McCoy, B. Davidson, G. Huffnagle, 2009 .

Keratinocyte growth factor induced epithelial proliferation facilitates retroviral–mediated gene transfer to distal lung epithelia in vivo

B. Davidson, J. Zabner, V. Slepushkin, 1999, The journal of gene medicine.

Keratinocyte growth factor induced epithelial proliferation facilitates retroviral–mediated gene transfer to distal lung epithelia in vivo

B. Davidson, J. Zabner, V. Slepushkin, 1999, The journal of gene medicine.

Alveolar macrophages inhibit retrovirus-mediated gene transfer to airway epithelia.

B. Davidson, S. Chada, J. Kline, 1997, Human gene therapy.

Proteines a ptd modifie

Haibin Xia, Q. Mao, B. Davidson, 2002 .

Huntington's disease: progress toward effective disease-modifying treatments and a cure.

B. Davidson, Carl D Johnson, 2010, Human molecular genetics.

Cell Apoptosis Ligand / Apo-2 Ligand Gene Induces Tumor TNF-Related Apoptosis-Inducing Adenoviral-Mediated Transfer of the Davidson

B. Davidson, T. Griffith, Richard D. Williams, 2000 .

Next-generation strategies for gene-targeted therapies of central nervous system disorders: A workshop summary

B. Davidson, G. Gao, Jill A. Morris, 2021, Molecular therapy : the journal of the American Society of Gene Therapy.

Influence of Cell Polarity on Retrovirus-Mediated Gene Transfer to Differentiated Human Airway Epithelia

B. Davidson, V. Slepushkin, P. McCray, 1998, Journal of Virology.

Amphibian ornithine aminotransferase: some general biological and chemical characteristics☆

B. Davidson, W. E. Boernke, 1982 .

Functional Repair of Human Donor Lungs by IL-10 Gene Therapy

Arthur S Slutsky, B. Davidson, J. Medin, 2009, Science Translational Medicine.

Impact of human interleukin-10 on vector-induced inflammation and early graft function in rat lung transplantation.

Stefan Fischer, B. Davidson, S. Keshavjee, 2003, American journal of respiratory cell and molecular biology.

In vivo treatment of hemophilia A and mucopolysaccharidosis type VII using nonprimate lentiviral vectors.

I. Martins, B. Davidson, P. McCray, 2001, Molecular therapy : the journal of the American Society of Gene Therapy.

Adenoviral-mediated gene transfer to rabbit synovium in vivo.

B. Davidson, J. Wilson, B. Roessler, 1993, The Journal of clinical investigation.

Timing of therapeutic intervention determines functional and survival outcomes in a mouse model of late infantile batten disease.

B. Davidson, R. Scheule, L. Shihabuddin, 2007, Molecular therapy : the journal of the American Society of Gene Therapy.

Attenuation of Stroke Size in Rats Using an Adenoviral Vector to Induce Overexpression of Interleukin-1 Receptor Antagonist in Brain

B. Davidson, Guo-Yuan Yang, A. Betz, 1995, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Adenovirus-mediated manganese superoxide dismutase gene transfer to hamster cheek pouch carcinoma cells.

B. Davidson, L. Oberley, F. Domann, 1997, Cancer research.

Adenovirus-mediated transfer of human factor IX gene in immunodeficient and normal mice: evidence for prolonged stability and activity of the transgene in liver.

K. Kurachi, B. Davidson, B. Roessler, 1996, Viral immunology.

Evaluating the state of the science for adeno-associated virus integration: An integrated perspective

R. Dolmetsch, K. Eggan, R. Crystal, 2022, Molecular therapy : the journal of the American Society of Gene Therapy.

Systemic and Central Nervous System Correction of Lysosomal Storage in Mucopolysaccharidosis Type VII Mice

B. Davidson, C. Stein, T. Derksen, 1999, Journal of Virology.

Hypoxanthine-guanine phosphoribosyltransferase (HPRT) expression in the central nervous system of HPRT-deficient mice following adenoviral-mediated gene transfer

B. Davidson, B. Roessler, D. Shewach, 1996, Neuroscience Letters.

Taking a break from huntingtin.

B. Davidson, 2012, Molecular therapy : the journal of the American Society of Gene Therapy.

Taking a Break From Huntingtin

B. Davidson, 2012, Molecular therapy. Nucleic acids.

Adenosine Deaminase Deficiency with

B. Davidson, P. Daddona, B. Mitchell, 1983 .

Direct plasmid mediated transfection of adult murine brain cells in vivo using cationic liposomes

B. Davidson, B. Roessler, 1994, Neuroscience Letters.

Retinal transduction profiles by high-capacity viral vectors

N. Brunetti‐Pierri, B. Davidson, G. Donofrio, 2014, Gene Therapy.

Feline immunodeficiency virus vectors. Gene transfer to mouse retina following intravitreal injection

B. Davidson, S. Sauter, T. Derksen, 2002, The journal of gene medicine.

Gene transfer to the nonhuman primate retina with recombinant feline immunodeficiency virus vectors.

B. Davidson, S. Russell, E. Stone, 2002, Human gene therapy.

lentiviral gene transfer Persistent expression of factor VIII in vivo following nonprimate

B. Davidson, P. McCray, M. Hickey, 2013 .

Poly-L-lysine improves gene transfer with adenovirus formulated in PLGA microspheres

B. Davidson, G. Jenkins, C. Matthews, 1999, Gene Therapy.

Progressive Muscular Dystrophy in (cid:97) -Sarcoglycan–deficient Mice

J. Sanes, B. Davidson, J. Faulkner, 1998 .

A 13 base pair deletion in exon 1 of HPRTIllinois forms a functional GUG initiation codon

B. Davidson, B. Roessler, N. Golovoy, 1994, Human Genetics.

CLN3 Deficient Cells Display Defects in the ARF1-Cdc42 Pathway and Actin-Dependent Events

B. Davidson, M. Stamnes, L. Tecedor, 2014, PloS one.

Osmoregulation of ceroid neuronal lipofuscinosis type 3 in the renal medulla.

I. Martins, B. Davidson, J. Stokes, 2010, American journal of physiology. Cell physiology.

Combined overexpression of ATXN1L and mutant ATXN1 knockdown by AAV rescue motor phenotypes and gene signatures in SCA1 mice

B. Davidson, Ashley B. Robbins, Ellie M. Carrell, 2022, Molecular therapy. Methods & clinical development.

Effects of antioxidant enzyme overexpression on the invasive phenotype of hamster cheek pouch carcinoma cells.

M. Hendrix, B. Davidson, E. Seftor, 1999, Free radical biology & medicine.

Gene Transfer to Rodent Brain with Recombinant Adenoviral Vectors: Effects of Infusion Parameters, Infectious Titer, and Virus Concentration on Transduction Volume

B. Davidson, A. Betz, P. Shakui, 1998, Experimental Neurology.

Superior cytotoxicity with ganciclovir compared with acyclovir and 1-beta-D-arabinofuranosylthymine in herpes simplex virus-thymidine kinase-expressing cells: a novel paradigm for cell killing.

B. Davidson, D. Shewach, L. Z. Rubsam, 1998, Cancer research.

A Chimeric Type 2 Adenovirus Vector with a Type 17 Fiber Enhances Gene Transfer to Human Airway Epithelia

B. Davidson, J. Zabner, M. Chillon, 1999, Journal of Virology.

Recombinant Adeno-Associated Viral Vector Types 4 and 5

B. Davidson, J. Chiorini, 2003 .

Recombinant adeno-associated viral vector types 4 and 5. Preparation and application for CNS gene transfer.

B. Davidson, J. Chiorini, 2003, Methods in molecular medicine.

Group D Adenoviruses Infect Primary Central Nervous System Cells More Efficiently than Those from Group C

B. Davidson, M. Welsh, J. Zabner, 1999, Journal of Virology.

Persistent expression of factor VIII in vivo following nonprimate lentiviral gene transfer.

B. Davidson, P. McCray, M. Hickey, 2005, Blood.

Stimulation of new bone formation by direct transfer of osteogenic plasmid genes.

S. Goldstein, B. Davidson, J. Bonadio, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Tripeptide probes for tripeptidyl protease I production via gene transfer.

Q. Mao, B. Davidson, D. Wiemer, 2003, Journal of medicinal chemistry.

Clarifying lysosomal storage diseases

B. Davidson, L. Tecedor, Mark L. Schultz, 2011, Trends in Neurosciences.

Immunolocalization and Adenoviral Vector-mediated Manganese Superoxide Dismutase Gene Transfer to Experimental Oral Tumors

B. Davidson, L. Oberley, J. Engelhardt, 2000, Journal of dental research.

Artificial microRNAs as siRNA shuttles: improved safety as compared to shRNAs in vitro and in vivo.

I. Martins, B. Davidson, R. Boudreau, 2009, Molecular therapy : the journal of the American Society of Gene Therapy.

Non-secretion of mutant proteins of the glaucoma gene myocilin in cultured trabecular meshwork cells and in aqueous humor.

Young H. Kwon, V. Sheffield, B. Davidson, 2001, Human molecular genetics.

Lysosomal storage diseases

B. Davidson, C. Tifft, F. Platt, 2018, Nature Reviews Disease Primers.

Artificial miRNAs mitigate shRNA-mediated toxicity in the brain: Implications for the therapeutic development of RNAi

Brian L. Gilmore, S. Harper, B. Davidson, 2008, Proceedings of the National Academy of Sciences.

Functional correction of established central nervous system deficits in an animal model of lysosomal storage disease with feline immunodeficiency virus-based vectors

Paul M. McCray, B. Davidson, D. Cory-Slechta, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Systemic Hyperosmolality Improves β-Glucuronidase Distribution and Pathology in Murine MPS VII Brain Following Intraventricular Gene Transfer

I. Martins, B. Davidson, C. Stein, 1999, Experimental Neurology.

Applying gene silencing technology to contraception.

B. Davidson, S. Ojeda, G. Dissen, 2012, Reproduction in domestic animals = Zuchthygiene.

Targeted gene silencing to induce permanent sterility.

B. Davidson, S. Ojeda, G. Dissen, 2012, Reproduction in domestic animals = Zuchthygiene.

Overexpression of interleukin-1 receptor antagonist in the mouse brain reduces ischemic brain injury

B. Davidson, Guo-Yuan Yang, A. Betz, 1997, Brain Research.

The limitations of central nervous systemdirected gene transfer

B. Davidson, 1995 .

Recombinant Human Adenovirus: Targeting to the Human Transferrin Receptor Improves Gene Transfer to Brain Microcapillary Endothelium

Haibin Xia, Q. Mao, B. Davidson, 2000, Journal of Virology.

CHIP Suppresses Polyglutamine Aggregation and Toxicity In Vitro and In Vivo

H. Paulson, S. Harper, B. Davidson, 2005, The Journal of Neuroscience.

Molecular basis of hypoxanthine-guanine phosphoribosyltransferase deficiency in ten subjects determined by direct sequencing of amplified transcripts.

B. Davidson, T. Palella, W. N. Kelley, 1989, The Journal of clinical investigation.

Current prospects for RNA interference-based therapies

Beverly L. Davidson, B. Davidson, P. McCray, 2011, Nature Reviews Genetics.

Adenovirus-Mediated Gene Therapy for Head and Neck Squamous Cell Carcinomas

B. Davidson, J. Zabner, J. Kern, 1996, The Annals of otology, rhinology, and laryngology.

RNAi therapy for neurodegenerative diseases.

B. Davidson, R. Boudreau, Ryan L. Boudreau, 2006, Current topics in developmental biology.

siRNA-mediated gene silencing in vitro and in vivo

Haibin Xia, H. Paulson, Haibin Xia, 2002, Nature Biotechnology.

Engineering a gene silencing viral construct that targets the cat hypothalamus to induce permanent sterility: An update.

B. Davidson, S. Ojeda, G. Dissen, 2017, Reproduction in domestic animals = Zuchthygiene.

Generation of hairpin-based RNAi vectors for biological and therapeutic application.

B. Davidson, R. Boudreau, Ryan L. Boudreau, 2012, Methods in enzymology.

Rational design of therapeutic siRNAs: minimizing off-targeting potential to improve the safety of RNAi therapy for Huntington's disease.

Ryan M Spengler, B. Davidson, R. Boudreau, 2011, Molecular therapy : the journal of the American Society of Gene Therapy.

RNAi medicine for the brain: progresses and challenges.

B. Davidson, R. Boudreau, Ryan L Boudreau, 2011, Human molecular genetics.

RNAi therapeutics for CNS disorders

B. Davidson, R. Boudreau, Ryan L. Boudreau, 2010, Brain Research.

Minimizing variables among hairpin-based RNAi vectors reveals the potency of shRNAs.

B. Davidson, A. M. Monteys, R. Boudreau, 2008, RNA.

Regional Variation of Splicing QTLs in Human Brain

B. Davidson, H. Yang, Zhicheng Pan, 2020, American journal of human genetics.

Disease-Associated Short Tandem Repeats Co-localize with Chromatin Domain Boundaries

Thomas G. Gilgenast, Jennifer E. Phillips-Cremins, Flora Tassone, 2018, Cell.

Membrane topology of CLN3, the protein underlying Batten disease

Haibin Xia, Haibin Xia, Q. Mao, 2003, FEBS letters.

Batten disease: evaluation of CLN3 mutations on protein localization and function.

B. Davidson, M. Bennett, Ronald E. Haskell, 2000, Human molecular genetics.

A Knock-In Reporter Model of Batten Disease

Q. Mao, S. Eliason, B. Davidson, 2007, The Journal of Neuroscience.

A knock-in reporter mouse model for Batten disease reveals predominant expression of Cln3 in visual, limbic and subcortical motor structures

B. Davidson, S. Ding, L. Tecedor, 2011, Neurobiology of Disease.

Preclinical safety of RNAi-mediated HTT suppression in the rhesus macaque as a potential therapy for Huntington's disease.

B. Davidson, S. Ojeda, J. McBride, 2011, Molecular therapy : the journal of the American Society of Gene Therapy.

Unravelling Endogenous MicroRNA System Dysfunction as a New Pathophysiological Mechanism in Machado-Joseph Disease.

B. Davidson, L. Pereira de Almeida, Isabel Onofre, 2017, Molecular therapy : the journal of the American Society of Gene Therapy.

Adenovirus Vector-Mediated Gene Transfer into Human Epileptogenic Brain Slices: Prospects for Gene Therapy in Epilepsy

B. Davidson, M. Kaplitt, P. Leone, 1997, Experimental Neurology.

Elucidation of transcriptome-wide microRNA binding sites in human cardiac tissues by Ago2 HITS-CLIP

Beverly L. Davidson, Ryan M Spengler, B. Davidson, 2016, Nucleic acids research.

Single nucleotide seed modification restores in vivo tolerability of a toxic artificial miRNA sequence in the mouse brain

Ryan M Spengler, B. Davidson, J. McBride, 2014, Nucleic acids research.

Functional microRNAs and target sites are created by lineage-specific transposition.

Ryan M Spengler, B. Davidson, Clayton K Oakley, 2014, Human molecular genetics.

Silencing mutant ATXN3 expression resolves molecular phenotypes in SCA3 transgenic mice.

H. Paulson, B. Davidson, R. Boudreau, 2013, Molecular therapy : the journal of the American Society of Gene Therapy.

Altered Purkinje cell miRNA expression and SCA1 pathogenesis

B. Davidson, M. Behlke, Gumei Liu, 2013, Neurobiology of Disease.

siSPOTR: a tool for designing highly specific and potent siRNAs for human and mouse

David A. Eichmann, Ryan M Spengler, B. Davidson, 2012, Nucleic acids research.

Silencing Mutant ATXN3 Expression Resolves Molecular Phenotypes in SCA3 Transgenic Mice.

H. Paulson, B. Davidson, R. Boudreau, 2013, Molecular therapy : the journal of the American Society of Gene Therapy.

Large-scale analysis of exonized mammalian-wide interspersed repeats in primate genomes.

Lan Lin, B. Davidson, Shihao Shen, 2009, Human molecular genetics.

Manipulation of Cell Physiology Enables Gene Silencing in Well-differentiated Airway Epithelia

B. Davidson, M. Behlke, S. Krishnamurthy, 2012, Molecular therapy. Nucleic acids.

Viral-mediated delivery of the late-infantile neuronal ceroid lipofuscinosis gene, TPP-I to the mouse central nervous system

B. Davidson, J. Chiorini, Ronald E. Haskell, 2003, Gene Therapy.

Dicer is required for proliferation, viability, migration and differentiation in corticoneurogenesis

B. Davidson, S. Fineberg, L. Tecedor, 2012, Neuroscience.

Recombinant adeno-associated virus type 2, 4, and 5 vectors: transduction of variant cell types and regions in the mammalian central nervous system.

I. Martins, R. Kotin, B. Davidson, 2000, Proceedings of the National Academy of Sciences of the United States of America.

CRISPR–Cas Gene Editing for Neurological Disease

B. Davidson, Bryan P. Simpson, 2019, Nervous System Drug Delivery.

CRISPR/Cas9 Editing of the Mutant Huntingtin Allele In Vitro and In Vivo

Beverly L. Davidson, B. Davidson, A. M. Monteys, 2017, Molecular therapy : the journal of the American Society of Gene Therapy.

Targeting Alzheimer's disease genes with RNA interference: an efficient strategy for silencing mutant alleles.

H. Paulson, B. Davidson, V. M. Miller, 2004, Nucleic acids research.

Gene therapy for ALS: A review

B. Davidson, D. Amado, Defne A. Amado, 2021, Molecular therapy : the journal of the American Society of Gene Therapy.

Singles Engage the RNA Interference Pathway

B. Davidson, A. M. Monteys, 2012, Cell.

Towards Therapy Using RNA Interference

B. Davidson, J. Alisky, 2004, American journal of pharmacogenomics : genomics-related research in drug development and clinical practice.

Optimization of Feline Immunodeficiency Virus Vectors for RNA Interference

S. Harper, B. Davidson, S. Fineberg, 2006, Journal of Virology.

371. Optimization of Feline Immunodeficiency Viral Vectors for RNA Interference

S. Harper, B. Davidson, S. Fineberg, 2006 .

In Vivo Gene Transfer Using a Nonprimate Lentiviral Vector Pseudotyped with Ross River Virus Glycoproteins

I. Martins, B. Davidson, D. A. Sanders, 2002, Journal of Virology.

Disruption of the beta-sarcoglycan gene reveals pathogenetic complexity of limb-girdle muscular dystrophy type 2E.

K. Campbell, B. Davidson, R. Cohn, 2000, Molecular cell.

Disruption of the b-Sarcoglycan Gene Reveals Pathogenetic Complexity of Limb-Girdle Muscular Dystrophy Type 2

K. Campbell, B. Davidson, R. Cohn, 2000 .

Adenovirus-mediated transgene expression in nonhuman primate brain.

C. Léránth, B. Davidson, C. Léránth, 1999, Human gene therapy.

The Importance of TGF-β in Murine Visceral Leishmaniasis

B. Davidson, M. Wilson, S. McGowan, 1998, The Journal of Immunology.

The importance of TGF-beta in murine visceral leishmaniasis.

B. Davidson, M. Wilson, S. McGowan, 1998, Journal of immunology.

Functional rescue of the sarcoglycan complex in the BIO 14.6 hamster using delta-sarcoglycan gene transfer.

K. Campbell, B. Davidson, F. Duclos, 1998, Molecular cell.

Factors that influence stability of recombinant adenoviral preparations for human gene therapy.

B. Davidson, B. Roessler, M. Croyle, 1998, Pharmaceutical development and technology.

Adenovirus mediated gene transfer to intestinal epithelial cells as a potential approach for oral delivery of peptides and proteins

G. Amidon, B. Davidson, E. Walter, 1997 .

A model system for in vivo gene transfer into the central nervous system using an adenoviral vector

Blake J. Roessler, Beverly L. Davidson, Edward D. Allen, 1993, Nature Genetics.

Dickkopf-1 is an epigenetically silenced candidate tumor suppressor gene in medulloblastoma.

A. Madan, B. Davidson, Jae-Geun Yoon, 2007, Neuro-oncology.

RNAi: a potential therapy for the dominantly inherited nucleotide repeat diseases

B. Davidson, E. Denovan‐Wright, 2006, Gene Therapy.

For Personal Use. Only Reproduce with Permission the Lancet Publishing Group. Molecular Medicine for the Brain: Silencing of Disease Genes with Rna Interference

H. Paulson, B. Davidson, Henry L Paulson, 2022 .

Broad distribution of ataxin 1 silencing in rhesus cerebella for spinocerebellar ataxia type 1 therapy.

Jeffrey H Kordower, B. Davidson, J. Kordower, 2015, Brain : a journal of neurology.

Broad therapeutic benefit after RNAi expression vector delivery to deep cerebellar nuclei: implications for spinocerebellar ataxia type 1 therapy.

B. Davidson, R. Boudreau, Megan S. Keiser, 2014, Molecular therapy : the journal of the American Society of Gene Therapy.

RNAi or overexpression: Alternative therapies for Spinocerebellar Ataxia Type 1

B. Davidson, K. A. Lennox, R. Boudreau, 2013, Neurobiology of Disease.

RNA interference improves motor and neuropathological abnormalities in a Huntington's disease mouse model.

H. Paulson, Q. Mao, S. Eliason, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Plasmid-Based RNA Interference

S. Harper, B. Davidson, 2005 .

Viral delivery of recombinant short hairpin RNAs.

S. Harper, B. Davidson, 2005, Methods in enzymology.

Allele-specific silencing of dominant disease genes

Haibin Xia, H. Paulson, Haibin Xia, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Toward therapy for DYT1 dystonia: Allele‐specific silencing of mutant TorsinA

H. Paulson, B. Davidson, P. Gonzalez-Alegre, 2003, Annals of neurology.

The HIV Tat protein transduction domain improves the biodistribution of β-glucuronidase expressed from recombinant viral vectors

Haibin Xia, Q. Mao, B. Davidson, 2001, Nature Biotechnology.

Proliferation induced by keratinocyte growth factor enhances in vivo retroviral-mediated gene transfer to mouse hepatocytes.

B. Davidson, T. Ulich, P. McCray, 1996, The Journal of clinical investigation.

An orally available, brain penetrant, small molecule lowers huntingtin levels by enhancing pseudoexon inclusion

R. Dolmetsch, M. Hild, B. Borowsky, 2022, Nature Communications.

Identification of PDGFR as a receptor for AAV-5 transduction

Giovanni Di Pasquale, D. Scudiero, A. Monks, 2003, Nature Medicine.

Lentivirus Vectors Pseudotyped with Filoviral Envelope Glycoproteins Transduce Airway Epithelia from the Apical Surface Independently of Folate Receptor Alpha

B. Davidson, D. A. Sanders, P. Sinn, 2003, Journal of Virology.

Adeno-Associated Virus Type 5 (AAV5) but Not AAV2 Binds to the Apical Surfaces of Airway Epithelia and Facilitates Gene Transfer

R. Kotin, B. Davidson, J. Chiorini, 2000, Journal of Virology.

Feline immunodeficiency virus vectors persistently transduce nondividing airway epithelia and correct the cystic fibrosis defect.

B. Davidson, T. Dubensky, S. Keshavjee, 1999, The Journal of clinical investigation.

Inflammatory responses and their impact on β-galactosidase transgene expression following adenovirus vector delivery to the primate caudate nucleus

B. Davidson, C. Léránth, A. Bothwell, 1999, Gene Therapy.

Gene expression from recombinant viral vectors in the central nervous system after blood-brain barrier disruption.

B. Davidson, B. Roessler, E. Neuwelt, 1995, Neurosurgery.

Infection efficiency of human and mouse embryonic stem cells using adenoviral and adeno-associated viral vectors.

B. Davidson, J. Mcwhir, J. Chiorini, 2003, Cloning and stem cells.

Differential effects of glial cell line-derived neurotrophic factor (GDNF) in the striatum and substantia nigra of the aged Parkinsonian rat

B. Davidson, T. Schallert, J. L. Tillerson, 1999, Gene Therapy.

Replication-Deficient Adenovirus Vector Transfer ofgfpReporter Gene into Supraoptic Nucleus and Subfornical Organ Neurons

B. Davidson, A. Johnson, T. Beltz, 1998, Experimental Neurology.

Adenovirus-mediated gene transfer to cultured nodose sensory neurons.

M. Chapleau, B. Davidson, R. V. Sharma, 1997, Brain research. Molecular brain research.

Dopaminergic Neurons Protected from Degeneration by GDNF Gene Therapy

B. Davidson, Y. Chiang, C. Hay, 1997, Science.

Adeno-associated virus type 5 reduces learning deficits and restores glutamate receptor subunit levels in MPS VII mice CNS.

I. Martins, B. Davidson, J. Chiorini, 2007, Molecular therapy : the journal of the American Society of Gene Therapy.

Assessment of ganciclovir toxicity to experimental intracranial gliomas following recombinant adenoviral-mediated transfer of the herpes simplex virus thymidine kinase gene by magnetic resonance imaging and proton magnetic resonance spectroscopy.

B. Ross, B. Davidson, B. Kim, 1995, Clinical cancer research : an official journal of the American Association for Cancer Research.

Regulated control of gene therapies by drug-induced splicing

B. Davidson, A. M. Monteys, L. Tecedor, 2021, Nature.

Allele-specific RNAi mitigates phenotypic progression in a transgenic model of Alzheimer's disease.

H. Paulson, B. Davidson, S. Moore, 2009, Molecular therapy : the journal of the American Society of Gene Therapy.

Integration Site Choice of a Feline Immunodeficiency Virus Vector

T. Casavant, T. Scheetz, B. Davidson, 2006, Journal of Virology.

NOTES Integration Site Choice of a Feline Immunodeﬁciency Virus Vector

T. Casavant, T. Scheetz, B. Davidson, 2006 .

Gene transfer to the brain using feline immunodeficiency virus-based lentivirus vectors.

B. Davidson, C. Stein, 2002, Methods in enzymology.

Viral-mediated gene transfer to mouse primary neural progenitor cells.

B. Davidson, S. Hughes, S. Sauter, 2002, Molecular therapy : the journal of the American Society of Gene Therapy.

Gene therapy for amyotrophic lateral sclerosis and other motor neuron diseases.

B. Davidson, J. Alisky, Beverly L. Davidson, 2000, Human gene therapy.

Transduction of murine cerebellar neurons with recombinant FIV and AAV5 vectors

B. Davidson, J. Chiorini, T. Dubensky, 2000, Neuroreport.

Review Gene Therapy for Amyotrophic Lateral Sclerosis and Other Motor Neuron Diseases

B. Davidson, J. Alisky, 2000 .

The lymphocytic choriomeningitis virus envelope glycoprotein targets lentiviral gene transfer vector to neural progenitors in the murine brain.

I. Martins, B. Davidson, C. Stein, 2005, Molecular therapy : the journal of the American Society of Gene Therapy.

The FASEB Journal express article 10.1096/fj.01-0421fje. Published online November 29, 2001.

B. Davidson, E. Rosen, J. Laterra, 2022 .

Transduction of nonhuman primate brain with adeno-associated virus serotype 1: vector trafficking and immune response.

B. Davidson, J. McBride, K. Bankiewicz, 2008, Human gene therapy.

Efficient Liver-specific Deletion of a Floxed Human Angiotensinogen Transgene by Adenoviral Delivery of Cre Recombinasein Vivo *

B. Davidson, D. Stec, C. Sigmund, 1999, The Journal of Biological Chemistry.

Techniques for Intracranial Stereotaxic Injections of Adeno‐Associated Viral Vectors in Adult Mice

B. Davidson, Megan S. Keiser, Y. Chen, 2018, Current protocols in mouse biology.

A NOVEL GENE DELIVERY METHOD TRANSDUCES PORCINE PANCREATIC DUCT EPITHELIAL CELLS

B. Davidson, P. McCray, A. Uc, 2013, Gene Therapy.

Adenosine deamination in human transcripts generates novel microRNA binding sites

Yi Xing, Debashish Bhattacharya, Glen M. Borchert, 2009, Human molecular genetics.

What does it take to bind CAR?

B. Davidson, Lane K Law, 2005, Molecular therapy : the journal of the American Society of Gene Therapy.

MiR-34a Represses Numbl in Murine Neural Progenitor Cells and Antagonizes Neuronal Differentiation

Beverly L. Davidson, B. Davidson, S. Fineberg, 2012, PloS one.

Progressive Muscular Dystrophy in α-Sarcoglycan–deficient Mice

John A. Faulkner, Beverly L. Davidson, Volker Straub, 1998, The Journal of cell biology.

Regulated control of gene therapies with a drug induced switch

B. Davidson, A. M. Monteys, L. Tecedor, 2020, bioRxiv.

The Genetic Basis of HGPRT Deficiency

B. Davidson, B. Roessler, 1993 .

Adenoviral-Mediated Transfer of the TNF-Related Apoptosis-Inducing Ligand/Apo-2 Ligand Gene Induces Tumor Cell Apoptosis1

B. Davidson, T. Ratliff, T. Griffith, 2000, The Journal of Immunology.

Mis-splicing in Huntington’s disease: harnessing the power of comparative transcriptomics

B. Davidson, Robert Wang, Yi Xing, 2021, Trends in Neurosciences.

In vivo SELEX for Identification of Brain-penetrating Aptamers

Mark A Behlke, B. Davidson, M. Behlke, 2013, Molecular therapy. Nucleic acids.

Diverse Splicing Patterns of Exonized Alu Elements in Human Tissues

Yi Xing, Shihao Shen, Beverly L. Davidson, 2008, PLoS genetics.

Expression of Escherichia coli β-Galactosidase and Rat HPRT in the CNS of Macaca mulatta Following Adenoviral Mediated Gene Transfer

B. Davidson, J. M. Latta, B. Roessler, 1994, Experimental Neurology.

Early adenovirus-mediated gene transfer effectively prevents muscular dystrophy in alpha-sarcoglycan-deficient mice

K. Campbell, B. Davidson, K. Donahue, 2000, Gene Therapy.

SUMO-2 and PIAS1 Modulate Insoluble Mutant Huntingtin Protein Accumulation

Jaclyn R. Gareau, E. Wanker, J. Marsh, 2013, Cell reports.

Sonic Hedgehog Controls the Phenotypic Fate and Therapeutic Efficacy of Grafted Neural Precursor Cells in a Model of Nigrostriatal Neurodegeneration

B. Davidson, A. Cole-Strauss, K. Steece-Collier, 2015, PloS one.

PIAS1 modulates striatal transcription, DNA damage repair, and SUMOylation with relevance to Huntington’s disease

A. Chakraborty, B. Leavitt, B. Davidson, 2021, Proceedings of the National Academy of Sciences.

PIAS1 Regulates Mutant Huntingtin Accumulation and Huntington’s Disease-Associated Phenotypes In Vivo

B. Davidson, L. Thompson, A. M. Monteys, 2016, Neuron.

The long non-coding RNA NEAT1 is elevated in polyglutamine repeat expansion diseases and protects from disease gene-dependent toxicities

Ryan M Spengler, B. Davidson, S. Ramachandran, 2018, Human molecular genetics.

Nonallele-specific silencing of mutant and wild-type huntingtin demonstrates therapeutic efficacy in Huntington's disease mice.

I. Martins, B. Davidson, J. McBride, 2009, Molecular therapy : the journal of the American Society of Gene Therapy.

Unique molecular signatures of disease brain endothelia provide a novel site for CNS-directed enzyme therapy

B. Davidson, Y. Chen, Michael Chang, 2009, Nature Network Boston.

Comparison of intracerebral inoculation and osmotic blood-brain barrier disruption for delivery of adenovirus, herpesvirus, and iron oxide particles to normal rat brain.

R. Weissleder, B. Davidson, G. Nilaver, 1995, The American journal of pathology.

Delivery of herpesvirus and adenovirus to nude rat intracerebral tumors after osmotic blood-brain barrier disruption.

B. Davidson, G. Nilaver, X. Breakefield, 1995, Proceedings of the National Academy of Sciences of the United States of America.

Overcoming Limitations Inherent in Sulfamidase to Improve Mucopolysaccharidosis IIIA Gene Therapy

B. Davidson, L. Tecedor, Y. Chen, 2018, Molecular therapy : the journal of the American Society of Gene Therapy.

Temporal Phenotypic Changes in Huntington’s Disease Models for Preclinical Studies

B. Davidson, S. St-cyr, Alicia R. Smith, 2022, Journal of Huntington's disease.

Hypoxanthine-Guanine Phosphoribosyltransferase Deficiency: Molecular Basis and Clinical Relevance

B. Davidson, T. Palella, W. Kelley, 1989 .

Superoxide production in vascular smooth muscle contributes to oxidative stress and impaired relaxation in atherosclerosis.

B. Davidson, D. Heistad, D. Gutterman, 1998, Circulation research.

Pulmonary inflammation induced by incomplete or inactivated adenoviral particles.

R. D. McCoy, R H Simon, B. Davidson, 1995, Human gene therapy.

Gene Transfer of Human Apoe Isoforms Results in Differential Modulation of Amyloid Deposition and Neurotoxicity in Mouse Brain

B. Hyman, B. Davidson, T. Spires-Jones, 2013, Science Translational Medicine.

Changes in expression of NMDA-NR1 receptor subunits in the rostral ventromedial medulla modulate pain behaviors

B. Davidson, K. Sluka, R. Walder, 2010, PAIN.

Viral Vectors for Gene Transfer

B. Davidson, Megan S. Keiser, Y. Chen, 2018, Current protocols in mouse biology.

Transcriptome sequencing reveals aberrant alternative splicing in Huntington's disease.

Yi Xing, Shihao Shen, Olga Pletnikova, 2016, Human molecular genetics.

Neurobiology of Disease CHIP Suppresses Polyglutamine Aggregation and Toxicity In Vitro and In Vivo

H. Paulson, S. Harper, B. Davidson, 2005 .

Toxicity after AAV delivery of RNAi expression constructs into nonhuman primate brain

B. Davidson, R. Wolf, E. Radaelli, 2021, Nature Medicine.

Eloise Hudry of Amyloid Deposition and Neurotoxicity in Mouse Brain Isoforms Results in Differential Modulation Apoe Gene Transfer of Human

B. Hyman, B. Davidson, T. Spires-Jones, 2013 .

Limited astrocyte-to-neuron conversion in the mouse brain using NeuroD1 overexpression.

B. Davidson, David E. Leib, A. M. Monteys, 2022, Molecular therapy : the journal of the American Society of Gene Therapy.

Design and Validation of a Multi-Point Injection Technology for MR-Guided Convection Enhanced Delivery in the Brain

T. Lucas, B. Davidson, Flavia Vitale, 2021, bioRxiv.

Modulating membrane fluidity corrects Batten disease phenotypes in vitro and in vivo

B. Davidson, E. Lysenko, L. Tecedor, 2018, Neurobiology of Disease.

Identification ofa Single Nucleotide ChangeintheHypoxanthine-Guanine Phosphoribosyltransferase Gene(HPRTyaie) Responsible forLesch-Nyhan Syndrome

B. Davidson, W. Kelley, 1989 .

A molecular survey of hypoxanthine-guanine phosphoribosyltransferase deficiency in man.

B. Davidson, C. Caskey, J. Wilson, 1986, The Journal of clinical investigation.

Striatal neurons directly converted from Huntington’s disease patient fibroblasts recapitulate age-associated disease phenotypes

Matheus B. Victor, B. Davidson, A. Yoo, 2018, Nature Neuroscience.

Platelet Activating Factor Receptor Activation Improves siRNA Uptake and RNAi Responses in Well-differentiated Airway Epithelia

B. Davidson, M. Behlke, S. Krishnamurthy, 2014, Molecular therapy. Nucleic acids.

717. RNAi Therapy for Dominant Neurodegenerative Diseases

H. Zoghbi, H. Paulson, Haibin Xia, 2004 .

Synthesis of normal and variant human hypoxanthine-guanine phosphoribosyltransferase in Escherichia coli.

J. Brown, B. Davidson, B. Roessler, 1993, Gene.

Identification of a single nucleotide change in the hypoxanthine-guanine phosphoribosyltransferase gene (HPRTYale) responsible for Lesch-Nyhan syndrome.

B. Davidson, T. Palella, S. Fujimori, 1989, The Journal of clinical investigation.

Hypoxanthine-guanine phosphoribosyltransferase. Genetic evidence for identical mutations in two partially deficient subjects.

B. Davidson, J. Wilson, T. Palella, 1988, The Journal of clinical investigation.

Genetic basis of hypoxanthine guanine phosphoribosyltransferase deficiency in a patient with the Lesch-Nyhan syndrome (HPRTFlint).

B. Davidson, T. Palella, M. Pashmforoush, 1988, Gene.

Structural consequences of point mutations in nine human HPRT variants.

B. Davidson, T. Palella, S. Fujimori, 1989 .

Human hypoxanthine-guanine phosphoribosyltransferase: a single nucleotide substitution in cDNA clones isolated from a patient with Lesch-Nyhan syndrome (HPRTMidland).

B. Davidson, T. Palella, W. Kelley, 1988, Gene.

Virus-Mediated Transduction of Murine Retina with Adeno-Associated Virus: Effects of Viral Capsid and Genome Size

R. Kotin, B. Davidson, J. Engelhardt, 2002, Journal of Virology.

Adeno-associated virus type 4 (AAV4) targets ependyma and astrocytes in the subventricular zone and RMS

I. Martins, B. Davidson, J. Chiorini, 2005, Gene Therapy.

Standard screening methods underreport AAV-mediated transduction and gene editing

B. Davidson, L. Eisenlohr, Sushila A. Toulmin, 2019, Nature Communications.

Striatal neurons directly converted from Huntington’s disease patient fibroblasts recapitulate age-associated disease phenotypes

Matheus B. Victor, B. Davidson, A. Yoo, 2018, Nature Neuroscience.

Widespread Dispersal of Cholera Toxin Subunit b to Brain and Spinal Cord Neurons Following Systemic Delivery

B. Davidson, J. Alisky, C. V. D. Wetering, 2002, Experimental Neurology.

Generation of Spinocerebellar Ataxia Type 2 induced pluripotent stem cell lines, CHOPi002-A and CHOPi003-A, from patients with abnormal CAG repeats in the coding region of the ATXN2 gene.

J. A. Maguire, B. Davidson, P. Gadue, 2019, Stem cell research.

Adeno-associated virus type 5: transduction efficiency and cell-type specificity in the primate retina.

R. Kotin, B. Davidson, S. Russell, 2003, Human gene therapy.

RNAi prevents and reverses phenotypes induced by mutant human ataxin‐1

B. Davidson, R. Corbau, P. Gonzalez-Alegre, 2016, Annals of neurology.

Connecdenn, A Novel DENN Domain-Containing Protein of Neuronal Clathrin-Coated Vesicles Functioning in Synaptic Vesicle Endocytosis

S. Harper, B. Davidson, P. McPherson, 2006, The Journal of Neuroscience.

Neuronal genetic rescue normalizes brain network dynamics in a lysosomal storage disorder despite persistent storage accumulation

Richard J. Chung, B. Davidson, E. Marsh, 2021, bioRxiv.

RNA Interference-Based Therapy for Spinocerebellar Ataxia Type 7 Retinal Degeneration

B. Davidson, A. Drack, R. Boudreau, 2014, PloS one.

Recent Advances in RNA Interference Therapeutics for CNS Diseases

B. Davidson, Megan S. Keiser, Pavitra S. Ramachandran, 2013, Neurotherapeutics.

A recombinant adenoviral vector expressing a soluble form of VCAM-1 inhibits VCAM-1/VLA-4 adhesion in transduced synoviocytes.

B. Davidson, J. Wilson, B. Roessler, 1995, Gene therapy.

Nonallele specific silencing of ataxin-7 improves disease phenotypes in a mouse model of SCA7.

B. Davidson, A. L. La Spada, Kellie A. Schaefer, 2014, Molecular therapy : the journal of the American Society of Gene Therapy.

RNA Interference of Human α-Synuclein in Mouse

N. Narayanan, B. Davidson, R. Boudreau, 2017, Front. Neurol..

Rho GTPases Modulate Entry of Ebola Virus and Vesicular Stomatitis Virus Pseudotyped Vectors

R. Mandell, B. Davidson, J. Chiorini, 2009, Journal of Virology.

Targeted viral delivery of Cre recombinase induces conditional gene deletion in cardiovascular circuits of the mouse brain.

B. Davidson, M. Cassell, P. Staber, 2004, Physiological genomics.

Sustained mobilization of endogenous neural progenitors delays disease progression in a transgenic model of Huntington's disease.

A. Benraiss, S. Goldman, R. Kageyama, 2013, Cell stem cell.

Hepatic diseases--hitting the target with inhibitory RNAs.

B. Davidson, 2003, The New England journal of medicine.

Gene Silencing Mediated by siRNA-binding Fusion Proteins Is Attenuated by Double-stranded RNA-binding Domain Structure

Brian L. Gilmore, B. Davidson, James C. Geoghegan, 2012, Molecular therapy. Nucleic acids.

Recombinant adeno-associated virus type 2, 4, and 5 vectors: transduction of variant cell types and regions in the mammalian central nervous system.

I. Martins, R. Kotin, B. Davidson, 2000, Proceedings of the National Academy of Sciences of the United States of America.

711. Allele-Specific Silencing of Mutant Huntingtin for Huntington's Disease Therapy

Brian L. Gilmore, S. Harper, B. Davidson, 2006 .

A recombinant bcl-x s adenovirus selectively induces apoptosis in cancer cells but not in normal bone marrow cells.

J. Dick, B. Davidson, M. Clarke, 1995, Proceedings of the National Academy of Sciences of the United States of America.

A simple method for the rapid generation of recombinant adenovirus vectors

Haibin Xia, B. Davidson, Ronald E. Haskell, 2000, Gene Therapy.

Deubiquitinase USP7 contributes to the pathogenicity of spinal and bulbar muscular atrophy.

B. Davidson, W. Gu, D. Merry, 2020, The Journal of clinical investigation.

Artificial miRNAs Targeting Mutant Huntingtin Show Preferential Silencing In Vitro and In Vivo.

Ryan M Spengler, B. Davidson, A. M. Monteys, 2015, Molecular therapy. Nucleic acids.

Cardiac mTORC1 Dysregulation Impacts Stress Adaptation and Survival in Huntington’s Disease

B. Davidson, John H. Lee, Y. Chen, 2018, Cell reports.

Cardiac mTORC 1 Dysregulation Impacts Stress Adaptation and Survival in Huntington ’ s Disease

B. Davidson, John H. Lee, Y. Chen, 2018 .

Doubling down on siRNAs in the brain

B. Davidson, 2019, Nature Biotechnology.

Multi‐site partitioned delivery of human tyrosine hydroxylase gene with phenotypic recovery in Parkinsonian rats

B. Davidson, Andrew Freese, M. During, 2000, Neuroreport.

Artificial miRNAs mitigate shRNA-mediated toxicity in the brain: Implications for the therapeutic development of RNAi

Brian L. Gilmore, S. Harper, B. Davidson, 2008, Proceedings of the National Academy of Sciences.

Techniques for Intracranial Stereotaxic Injections of Adeno‐Associated Viral Vectors in Adult Mice

B. Davidson, Megan S. Keiser, Y. Chen, 2018, Current protocols in mouse biology.

AAV gene transfer delays disease onset in a TPP1-deficient canine model of the late infantile form of Batten disease

B. Davidson, E. Lysenko, L. Tecedor, 2015, Science Translational Medicine.

Short Communications Genetic basis of hypoxanthine guanine phosphoribosyltransferase deficiency in a patient with the Lesch-Nyhan syndrome (HPRT,,,,,) (Recombinant DNA; cDNA cloning; RNase A mapping; secondary structure prediction; hyperuricemia; gout; phage ngtll vector)

B. Davidson, T. Palella, M. Pashmforoush, 2002 .

Adenovirus Serotype 30 Fiber Does Not Mediate Transduction via the Coxsackie-Adenovirus Receptor

B. Davidson, Lane K Law, 2002, Journal of Virology.

Coxsackie-Adenovirus Receptor Mediate Transduction via the Adenovirus Serotype 30 Fiber Does Not

B. Davidson, Lane K Law, 2014 .

Changes in expression of NMDA-NR1 receptor subunits in the rostral ventromedial medulla modulate pain behaviors

B. Davidson, K. Sluka, R. Walder, 2010, PAIN.

Broad therapeutic benefit after RNAi expression vector delivery to deep cerebellar nuclei: implications for spinocerebellar ataxia type 1 therapy.

B. Davidson, Megan S. Keiser, Ryan L. Boudreau, 2014, Molecular therapy : the journal of the American Society of Gene Therapy.

Gene transfer to brain and spinal cord using recombinant adenoviral vectors.

B. Davidson, J. Alisky, 2004, Methods in molecular biology.

Exploring RNA interference as a therapeutic strategy in polyglutamine disease

H. Paulson, Haibin Xia, B. Davidson, 2003 .

Rational design of therapeutic siRNAs: minimizing off-targeting potential to improve the safety of RNAi therapy for Huntington's disease.

Ryan M Spengler, B. Davidson, Ryan L. Boudreau, 2011, Molecular Therapy.