S. Elbashir

发表

RNA interference is mediated by 21- and 22-nucleotide RNAs.

T. Tuschl, W. Lendeckel, S. Elbashir, 2001, Genes & development.

Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs

Matthias John, Akin Akinc, K. G. Rajeev, 2004, Nature.

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

T. Tuschl, A. Yalçin, W. Lendeckel, 2001, Nature.

Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysate

T. Tuschl, W. Lendeckel, S. Elbashir, 2001, The EMBO journal.

Analysis of gene function in somatic mammalian cells using small interfering RNAs.

T. Tuschl, S. Elbashir, J. Harborth, 2002, Methods.

Identification of essential genes in cultured mammalian cells using small interfering RNAs.

K Weber, T. Tuschl, S. Elbashir, 2001, Journal of cell science.

A lipid-encapsulated mRNA encoding a potently neutralizing human monoclonal antibody protects against chikungunya infection

James E. Crowe, Giuseppe Ciaramella, Michael S. Diamond, 2019, Science Immunology.

found in the U 2-dependent spliceosome The human 18 S U 11 / U 12 snRNP contains a set of novel proteins not

T. Tuschl, R. Rauhut, S. Elbashir, 2004 .

Sequence, chemical, and structural variation of small interfering RNAs and short hairpin RNAs and the effect on mammalian gene silencing.

Thomas Tuschl, T. Tuschl, S. Scaringe, 2003, Antisense & nucleic acid drug development.

mRNA-1273 and Ad26.COV2.S vaccines protect against the B.1.621 variant of SARS-CoV-2

M. Diamond, S. Elbashir, Y. Kawaoka, 2021, bioRxiv.

Boosting with variant-matched or historical mRNA vaccines protects against Omicron infection in mice

M. Diamond, S. Elbashir, Y. Lai, 2022, Cell.

Bivalent SARS-CoV-2 mRNA vaccines increase breadth of neutralization and protect against the BA.5 Omicron variant

M. Diamond, G. Chuang, S. Elbashir, 2022, bioRxiv.

A multiclade env–gag VLP mRNA vaccine elicits tier-2 HIV-1-neutralizing antibodies and reduces the risk of heterologous SHIV infection in macaques

J. Mascola, S. Elbashir, D. Follmann, 2021, Nature Medicine.

SARS-CoV-2 mRNA vaccine design enabled by prototype pathogen preparedness Preview

J. Mascola, R. Baric, S. Elbashir, 2020 .

Development of SARS-CoV-2 mRNA vaccines encoding spike N-terminal and receptor binding domains

Larissa B. Thackray, M. Diamond, S. Elbashir, 2022, bioRxiv.

Immunogenicity generated by mRNA vaccine encoding VZV gE antigen is comparable to adjuvanted subunit vaccine and better than live attenuated vaccine in nonhuman primates.

D. Hazuda, S. Elbashir, K. Vora, 2020, Vaccine.

Boosting with Omicron-matched or historical mRNA vaccines increases neutralizing antibody responses and protection against B.1.1.529 infection in mice

M. Diamond, S. Elbashir, L. Thackray, 2022, bioRxiv.

Altering the mRNA-1273 dosing interval impacts the kinetics, quality, and magnitude of immune responses in mice

S. Elbashir, C. Hsiao, A. Carfi, 2022, Frontiers in Immunology.

Bivalent SARS-CoV-2 mRNA vaccines increase breadth of neutralization and protect against the BA.5 Omicron variant in mice

Larissa B. Thackray, M. Diamond, G. Chuang, 2022, Nature Medicine.

Rational Design and In Vivo Characterization of mRNA-Encoded Broadly Neutralizing Antibody Combinations against HIV-1

Kimberly J. Hassett, S. Elbashir, A. Carfi, 2022, Antibodies.

SARS-CoV-2 mRNA Vaccine Design Enabled by Prototype Pathogen Preparedness

Rebecca J. Loomis, J. Mascola, R. Baric, 2020, Nature.

SARS-CoV-2 mRNA Vaccine Development Enabled by Prototype Pathogen Preparedness

Rebecca J. Loomis, J. Mascola, R. Baric, 2020, bioRxiv.

Distinct sensitivities to SARS-CoV-2 variants in vaccinated humans and mice

B. Pulendran, M. Diamond, S. Elbashir, 2022, bioRxiv.

Comprehensive evaluation of canonical versus Dicer-substrate siRNA in vitro and in vivo.

M. Manoharan, S. Elbashir, G. Hinkle, 2012, RNA.

siRNA in vitro and in vivo Comprehensive evaluation of canonical versus Dicer-substrate Material Supplemental

M. Manoharan, S. Elbashir, G. Hinkle, 2012 .

Activation of LDL receptor expression by small RNAs complementary to a noncoding transcript that overlaps the LDLR promoter.

D. Corey, M. Manoharan, S. Elbashir, 2010, Chemistry & biology.

The human 18S U11/U12 snRNP contains a set of novel proteins not found in the U2-dependent spliceosome.

Henning Urlaub, Thomas Tuschl, Reinhard Rauhut, 2004, RNA.

Lipid nanoparticles improve activity of single-stranded siRNA and gapmer antisense oligonucleotides in animals.

M. Manoharan, S. Elbashir, S. Crooke, 2013, ACS chemical biology.

Evaluation of the safety, tolerability and pharmacokinetics of ALN-RSV01, a novel RNAi antiviral therapeutic directed against respiratory syncytial virus (RSV).

S. Elbashir, J. Harborth, I. Toudjarska, 2008, Antiviral research.

RNA Interference-Mediated Silencing of the Respiratory Syncytial Virus Nucleocapsid Defines a Potent Antiviral Strategy

Svetlana Shulga Morskaya, M. Manoharan, M. Van Ranst, 2009, Antimicrobial Agents and Chemotherapy.

Transcriptional regulation by small RNAs at sequences downstream from 3' gene termini.

D. Corey, S. Elbashir, S. Younger, 2010, Nature chemical biology.

mRNA-1273 Protects against SARS-CoV-2 Beta Infection in Nonhuman Primates

S. Elbashir, E. Boritz, D. Douek, 2021, Nature Immunology.

Evaluation of mRNA-1273 against SARS-CoV-2 B.1.351 Infection in Nonhuman Primates

S. Elbashir, D. Douek, N. Sullivan, 2021, bioRxiv.

Variant SARS-CoV-2 mRNA vaccines confer broad neutralization as primary or booster series in mice

S. Elbashir, B. Graham, A. McDermott, 2021, Vaccine.

Protective activity of mRNA vaccines against ancestral and variant SARS-CoV-2 strains

Larissa B. Thackray, M. Diamond, S. Elbashir, 2021, Science Translational Medicine.

Variant SARS-CoV-2 mRNA vaccines confer broad neutralization as primary or booster series in mice

S. Elbashir, B. Graham, A. McDermott, 2021, bioRxiv.

Protective activity of mRNA vaccines against ancestral and variant SARS-CoV-2 strains

Larissa B. Thackray, M. Diamond, S. Elbashir, 2021, bioRxiv.