J. Jelinek

发表

Silencing of bidirectional promoters by DNA methylation in tumorigenesis.

J. Issa, J. Shu, J. Jelinek, 2006, Cancer research.

Dnmt3a is essential for hematopoietic stem cell differentiation

J. Berg, J. Issa, J. Jelinek, 2011, Nature Genetics.

Epigenetic Reprogramming of HOXC10 in Endocrine-Resistant Breast Cancer

Jian Chen, Steffi Oesterreich, Adrian V. Lee, 2014, Science Translational Medicine.

Sex chromosomes drive gene expression and regulatory dimorphisms in mouse embryonic stem cells

J. Jelinek, J. Madzo, R. Werner, 2017, Biology of Sex Differences.

Targeting CDK9 Reactivates Epigenetically Silenced Genes in Cancer

C. Zahnow, B. Garcia, S. Baylin, 2018, Cell.

Correlation between CpG methylation profiles and hormone receptor status in breast cancers

Xin Hu, Sijin Wen, Yinhua Yu, 2007, Breast Cancer Research.

polycythemia Mutations in the VHL gene in sporadic apparently congenital

J. Jelinek, J. Prchal, L. Krishnamurti, 2013 .

Mutations in the VHL gene in sporadic apparently congenital polycythemia.

J. Jelinek, J. Prchal, L. Krishnamurti, 2003, Blood.

TET1 is a maintenance DNA demethylase that prevents methylation spreading in differentiated cells

J. Issa, J. Jelinek, M. Estecio, 2014, Nucleic acids research.

Epidermal growth factor receptor copy number alterations correlate with poor clinical outcome in patients with head and neck squamous cancer.

Diane D. Liu, J. Lee, J. Issa, 2007, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Comprehensive Promoter Methylation Analysis of Genes on 5q31.1 in MDS and AML.

J. Issa, J. Jelinek, Lanlan Shen, 2005 .

Genome architecture marked by retrotransposons modulates predisposition to DNA methylation in cancer.

B. Czerniak, J. Issa, J. Jelinek, 2010, Genome research.

inactivation state locus does not always reflect X chromosome AR Methylation of

B. Cairns, N. Agarwal, J. Jelinek, 2014 .

Discrimination of polycythemias and thrombocytoses by novel, simple, accurate clonality assays and comparison with PRV-1 expression and BFU-E response to erythropoietin.

J. Jelinek, J. Prchal, J. Prchal, 2003, Blood.

A novel isoform of TET1 that lacks a CXXC domain is overexpressed in cancer

J. Issa, J. Jelinek, J. Madzo, 2017, Nucleic acids research.

Induction of hypomethylation and molecular response after decitabine therapy in patients with chronic myelomonocytic leukemia.

J. Issa, J. Jelinek, Lanlan Shen, 2008, Blood.

Predictive Biomarkers and Personalized Medicine Progesterone Receptor Isoform-Specific Promoter Methylation : Association of PRA Promoter Methylation with Worse Outcome in Breast Cancer Patients

S. Hilsenbeck, J. Issa, J. Jelinek, 2011 .

Concordance of assays designed for the quantification of JAK2V617F: a multicenter study

S. Ellard, J. Jelinek, N. Kröger, 2009, Haematologica.

Award Number: W81XWH-05-1-0535 TITLE: DNA Methylation as an Epigenetic Factor in the Development and Progression of Polycythemia Vera

Yongli, J. Issa, J. Jelinek, 2006 .

JAK2 mutation 1849G>T is rare in acute leukemias but can be found in CMML, Philadelphia chromosome-negative CML, and megakaryocytic leukemia.

E. Estey, J. Issa, J. Jelinek, 2005, Blood.

Promoter methylation changes in ALOX12 and AIRE1: novel epigenetic markers for atherosclerosis

J. Issa, J. Jelinek, S. Kwon, 2020, Clinical Epigenetics.

Identification of Novel Tumor Markers in Prostate, Colon and Breast Cancer by Unbiased Methylation Profiling

J. Issa, J. Jelinek, Lanlan Shen, 2008, PLoS ONE.

Nerve Injury-Induced Chronic Pain Is Associated with Persistent DNA Methylation Reprogramming in Dorsal Root Ganglion

J. Issa, J. Jelinek, G. Laumet, 2018, The Journal of Neuroscience.

Zebrafish embryos as a screen for DNA methylation modifications after compound exposure.

J. Pennings, J. Issa, J. Jelinek, 2016, Toxicology and applied pharmacology.

Minimal role of base excision repair in TET-induced global DNA demethylation in HEK293T cells

J. Issa, J. Jelinek, T. Qin, 2015, Epigenetics.

Liver DNA methylation analysis in adult female C57BL/6JxFVB mice following perinatal exposure to bisphenol A.

J. Pennings, J. Issa, J. Jelinek, 2015, Toxicology letters.

Transfection of murine multi-potent haemopoietic stem cells with an E. coli DNA alkyltransferase gene confers resistance to the toxic effects of alkylating agents.

J. Jelinek, G. Margison, T. Dexter, 1988, Carcinogenesis.

Linear type trait analysis in the genetic resource ofthe Old Kladrub Horse

J. Jelinek, A. Scholz, W. Schlote, 1999 .

Identification of Novel Tumor Markers in Prostate, Colon and Breast Cancer by Unbiased Methylation Profiling

Michael Ittmann, Yinhua Yu, J. Issa, 2008, PloS one.

TRAIL (Apo2L) suppresses growth of primary human leukemia and myelodysplasia progenitors

J. Jelinek, L. Andĕra, T. Stopka, 2002, Leukemia.

Mixed myelodysplastic and myeloproliferative syndromes.

J. Jelinek, M. Adamkov, K. Michalová, 1996, Leukemia research.

Unusually Long Survival of a 67-Year-Old Patient with Near-Tetraploid Acute Myeloid Leukemia M0 without Erythroblastic and Megakaryocytic Dysplasia

J. Jelinek, H. Klamová, Z. Zemanová, 2011, Acta Haematologica.

Diamond blackfan anemia stem cells fail to repopulate erythropoiesis in NOD/SCID mice.

J. Jelinek, D. Pospíšilová, T. Stopka, 2003, Blood Cells, Molecules & Diseases.

61 CFU-GM growth and survival in 258 patients with myelodysplastic syndromes

J. Jelinek, R. Neuwirtová, A. Smolikova, 1997 .

Mixed myelodysplastic and myeloproliferative syndromes.

J. Jelinek, M. Adamkov, K. Michalová, 1996, Leukemia research.

Mutations and promoter methylation status of NPM1 in myeloproliferative disorders.

J. Issa, J. Jelinek, Y. Oki, 2006, Haematologica.

Uphill distributional shift of an endangered habitat specialist

J. Jelinek, J. Horák, Karel Chobot, 2011, Journal of Insect Conservation.

Mechanisms of resistance to 5-aza-2 (cid:1) -deoxycytidine in human cancer cell lines

J. Issa, J. Shu, J. Jelinek, 2009 .

Oxygen-dependent regulation of erythropoiesis.

J. Jelinek, J. Prchal, 2004, Methods in enzymology.

Interleukin-3-specific modification of cell membrane "fluidity" of haemopoietic cells.

J. Jelinek, T. Dexter, R. Dale, 1988, Growth factors.

Progesterone Receptor Isoform-Specific Promoter Methylation: Association of PRA Promoter Methylation with Worse Outcome in Breast Cancer Patients

S. Hilsenbeck, J. Issa, J. Jelinek, 2011, Clinical Cancer Research.

Aberrant CpG Island Methylation in AML Is Associated with Disease Progression and Relapse.

J. Issa, J. Jelinek, C. Bueso-Ramos, 2006 .

RPS19 and JAK2 genes are not silenced by DNA methylation in diamond blackfan anemia.

J. Issa, J. Jelinek, D. Pospíšilová, 2007, Journal of pediatric hematology/oncology.

Fusobacterium in colonic flora and molecular features of colorectal carcinoma.

M. Toyota, J. Issa, J. Jelinek, 2014, Cancer research.

Ultraviolet radiation modulates DNA methylation in melanocytes

J. Issa, J. Jelinek, M. Zaidi, 2021, bioRxiv.

CpG island methylation profiling in human melanoma cell lines

J. Issa, J. Jelinek, Lanlan Shen, 2009, Melanoma research.

Genome-wide DNA methylation analysis identifies promoter hypermethylation in canine malignant melanoma.

J. Jelinek, Takashi Kimura, K. Aoshima, 2020, Research in veterinary science.

Sensitive and specific detection of early gastric cancer with DNA methylation analysis of gastric washes.

Yi Guo, M. Toyota, J. Issa, 2009, Gastroenterology.

Three cases of near-tetraploid acute myeloid leukemias originating in pluripotent myeloid progenitors.

J. Jelinek, Z. Zemanová, K. Michalová, 1998, Leukemia research.

Phase I Trial of Sequential Low-Dose 5-Aza-2′-Deoxycytidine Plus High-Dose Intravenous Bolus Interleukin-2 in Patients with Melanoma or Renal Cell Carcinoma

Kelly B. Moran, H. Dressman, J. Issa, 2006, Clinical Cancer Research.

Effect of Cytarabine and Decitabine in Combination in Human Leukemic Cell Lines

J. Issa, J. Jelinek, A. Yang, 2007, Clinical Cancer Research.

Long-term protection of hematopoiesis against the cytotoxic effects of multiple doses of nitrosourea by retrovirus-mediated expression of human O6-alkylguanine-DNA-alkyltransferase.

J. Jelinek, T. Dexter, C. Stocking, 1996, Blood.

New DNA Methylation Markers and Global DNA Hypomethylation Are Associated with Oral Cancer Development

Edward S. Kim, Jing Wang, S. Lippman, 2015, Cancer Prevention Research.

TET1-Mediated Hypomethylation Activates Oncogenic Signaling in Triple-Negative Breast Cancer.

J. Issa, J. Jelinek, J. Madzo, 2018, Cancer research.

DNA methylation landscape of 16 canine somatic tissues by methylation-sensitive restriction enzyme-based next generation sequencing

J. Jelinek, Genki Ishihara, J. Yamagishi, 2021, Scientific Reports.

TET2 Mutations Affect Non-CpG Island DNA Methylation at Enhancers and Transcription Factor-Binding Sites in Chronic Myelomonocytic Leukemia.

J. Issa, J. Jelinek, M. Estecio, 2015, Cancer research.

Title TET 2 mutations affect non-CpG island DNA methylation at enhancers and transcription factor binding sites in chronic myelomonocytic leukemia

J. Issa, J. Jelinek, M. Estecio, 2015 .

TET 2 mutations affect non-CpG island DNA methylation at enhancers and transcription factor binding sites in chronic myelomonocytic leukemia

J. Issa, J. Jelinek, M. Estecio, 2015 .

The epigenome of AML stem and progenitor cells

J. Issa, J. Jelinek, M. Estecio, 2013, Epigenetics.

TET1 and TDG suppress intestinal tumorigenesis by down-regulating the inflammatory and immune response pathways

Yan Zhou, J. Issa, J. Jelinek, 2019, bioRxiv.

Architecture of epigenetic reprogramming following Twist1-mediated epithelial-mesenchymal transition

J. Issa, J. Jelinek, M. Estécio, 2013, Genome Biology.

Delta DNMT3B variants regulate DNA methylation in a promoter-specific manner.

J. Issa, J. Jelinek, Lanlan Shen, 2007, Cancer research.

Conserved DNA methylation patterns in healthy blood cells and extensive changes in leukemia measured by a new quantitative technique

J. Issa, J. Jelinek, M. Estecio, 2012, Epigenetics.

LINE-1 Hypomethylation in Cancer Is Highly Variable and Inversely Correlated with Microsatellite Instability

J. Issa, J. Jelinek, Lanlan Shen, 2007, PloS one.

Hypomethylation of TET2 Target Genes Identifies a Curable Subset of Acute Myeloid Leukemia.

J. Issa, J. Jelinek, H. Kantarjian, 2016, Journal of the National Cancer Institute.

Effects of TET2 mutations on DNA methylation in chronic myelomonocytic leukemia

J. Issa, J. Jelinek, Lanlan Shen, 2012, Epigenetics.

Genome-wide DNA methylation profile in feline haematological tumours: A preliminary study.

J. Jelinek, M. Takiguchi, J. Yamazaki, 2021, Research in veterinary science.

J. Issa, J. Jelinek, Lanlan Shen, 2007, Clinical Cancer Research.

Thymine DNA glycosylase as a novel target for melanoma

M. Einarson, J. Jelinek, Hongmao Sun, 2019, Oncogene.

Disruption of oxygen homeostasis underlies congenital Chuvash polycythemia

David Mole, Kiichi Hirota, Enli Liu, 2002, Nature Genetics.

Dnmt 3 a is essential for hematopoietic stem cell differentiation

J. Berg, J. Issa, J. Jelinek, 2013 .

Differentially methylated genes and androgen receptor re-expression in small cell prostate carcinomas

J. Issa, J. Jelinek, W. Chung, 2016, Epigenetics.

Chromatin remodeling is required for gene reactivation after decitabine-mediated DNA hypomethylation.

J. Issa, J. Jelinek, Y. Boumber, 2010, Cancer research.

BRCA1 promoter methylation status does not predict response to tamoxifen in sporadic breast cancer patients

S. Hilsenbeck, S. McGuire, J. Jelinek, 2012, Breast Cancer Research and Treatment.

Granulocyte colony‐stimulating factor treatment of mice modulates differently the sensitivity of blood and bone marrow hematopoietic progenitors to retroviral vector infection

J. Jelinek, 1993, Stem cells.

Tyrosine kinase inhibitor-induced defects in DNA repair sensitize FLT3(ITD)-positive leukemia cells to PARP1 inhibitors.

L. Bullinger, J. Jelinek, R. Płoski, 2018, Blood.

Chromosome 5q deletion and epigenetic suppression of the gene encoding α-catenin (CTNNA1) in myeloid cell transformation

Michael F Clarke, C. Bloomfield, A. Look, 2007, Nature Medicine.

Mechanisms of Resistance to Decitabine in the Myelodysplastic Syndrome

Nianxiang Zhang, J. Issa, J. Jelinek, 2011, PloS one.

DNA methylation predicts survival and response to therapy in patients with myelodysplastic syndromes.

D. Berry, E. Estey, Yi Guo, 2010, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Mechanisms of resistance to 5-aza-2'-deoxycytidine in human cancer cell lines.

J. Issa, J. Jelinek, Taichun Qin, 2009, Blood.

Phase II study of low-dose decitabine in patients with chronic myelogenous leukemia resistant to imatinib mesylate.

J. Issa, J. Jelinek, H. Kantarjian, 2005, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Dynamic changes in DNA methylation patterns in canine lymphoma cell lines demonstrated by genome-wide quantitative DNA methylation analysis.

J. Jelinek, M. Inaba, A. Tsukamoto, 2018, Veterinary journal.

Detection of Bladder Cancer Using Novel DNA Methylation Biomarkers in Urine Sediments

Yair Lotan, Shoudan Liang, Y. Lotan, 2011, Cancer Epidemiology, Biomarkers & Prevention.

Hypomethylation in MTNR1B: a novel epigenetic marker for atherosclerosis profiling using stenosis radiophenotype and blood inflammatory cells

J. Issa, J. Jelinek, J. Cha, 2023, Clinical Epigenetics.

Decitabine impact on the endocytosis regulator RhoA, the folate carriers RFC1 and FOLR1, and the glucose transporter GLUT4 in human tumors

I. Wistuba, J. Issa, J. Jelinek, 2014, Clinical Epigenetics.

Single cell transcriptomic analysis reveals cellular diversity of murine esophageal epithelium

J. Jelinek, Yinfei Tan, Marie-Pier Tétreault, 2022, Nature Communications.

Single cell transcriptomic analysis reveals cellular diversity of murine esophageal epithelium and age-associated mitochondrial dysfunction

J. Jelinek, Marie-Pier Tétreault, J. Madzo, 2021, bioRxiv.

DNA Methylation Signature Reveals Cell Ontogeny of Renal Cell Carcinomas

T. Ho, C. Creighton, P. Tamboli, 2016, Clinical Cancer Research.

Caloric restriction delays age-related methylation drift

R. Colman, J. Issa, J. Jelinek, 2017, Nature Communications.

Concordant DNA Methylation in Synchronous Colorectal Carcinomas

J. Issa, J. Jelinek, Lanlan Shen, 2009, Cancer Prevention Research.

Decitabine Effect on Tumor Global DNA Methylation and Other Parameters in a Phase I Trial in Refractory Solid Tumors and Lymphomas

I. Wistuba, J. Issa, J. Jelinek, 2009, Clinical Cancer Research.

Mechanisms of naturally occurring resistance to 5-Aza-2'-deoxycytidine in human cancer cell lines

J. Issa, J. Jelinek, Taichun Qin, 2007 .

DNA Methylation Profiles of Primary Colorectal Carcinoma and Matched Liver Metastasis

Yi Guo, J. Issa, J. Jelinek, 2011, PloS one.

Caloric restriction delays age-related methylation drift

R. Colman, J. Issa, J. Jelinek, 2017, Nature Communications.

A CpG island methylator phenotype in acute myeloid leukemia independent of IDH mutations and associated with a favorable outcome

J. Issa, J. Jelinek, H. Kantarjian, 2016, Leukemia.

Methylation of AR locus does not always reflect X chromosome inactivation state.

B. Cairns, N. Agarwal, J. Jelinek, 2012, Blood.

Nianxiang Zhang, J. Issa, J. Jelinek, 2014, Genome research.

Polycythemia vera is not initiated by JAK2V617F mutation.

J. Jelinek, S. Verstovsek, S. Swierczek, 2007, Experimental hematology.

Frequent Alteration of MLL3 Frameshift Mutations in Microsatellite Deficient Colorectal Cancer

M. Toyota, J. Issa, J. Jelinek, 2011, PloS one.

Sex chromosomes drive gene expression and regulatory dimorphisms in mouse embryonic stem cells

J. Jelinek, J. Madzo, R. Werner, 2017, Biology of Sex Differences.

Non-pathogenic microbiota accelerate age-related CpG Island methylation in colonic mucosa

J. Issa, J. Jelinek, A. Sun, 2022, Epigenetics.

Microbiota Accelerates Age-Related CpG Island Methylation in Colonic Mucosa

J. Issa, J. Jelinek, A. Sun, 2020 .

Search for genetic determinants of individual variability of the erythropoietin response to high altitude.

B. Levine, J. Jelinek, D. Stockton, 2003, Blood cells, molecules & diseases.

Digital Restriction Enzyme Analysis of Methylation (DREAM).

J. Issa, J. Jelinek, S. Liang, 2018, Methods in molecular biology.

DREAM: A Simple Method for DNA Methylation Profiling by High-throughput Sequencing.

J. Jelinek, J. Madzo, 2016, Methods in molecular biology.

Colorectal carcinomas with CpG island methylator phenotype 1 frequently contain mutations in chromatin regulators.

M. Toyota, J. Issa, J. Jelinek, 2014, Gastroenterology.

Genome-wide DNA methylation analysis in canine gastrointestinal lymphoma

J. Jelinek, M. Takiguchi, N. Yokoyama, 2020, The Journal of veterinary medical science.

A novel dual function retrovirus expressing multidrug resistance 1 and O6-alkylguanine-DNA-alkyltransferase for engineering resistance of haemopoietic progenitor cells to multiple chemotherapeutic agents

J. Jelinek, T. Dexter, W. Ostertag, 1999, Gene Therapy.

Accelerated aging in normal breast tissue of women with breast cancer

C. Sapienza, J. Issa, J. Jelinek, 2021, Breast cancer research : BCR.

High folic acid intake increases methylation-dependent expression of Lsr and dysregulates hepatic cholesterol homeostasis.

J. Issa, J. Jelinek, R. Rozen, 2020, The Journal of nutritional biochemistry.

Novel treatment strategy of targeting epigenetic dysregulation in pancreatic neuroendocrine tumors.

J. Jelinek, R. Platoff, J. Madzo, 2023, Surgery.

DNA methylation does not stably lock gene expression but instead serves as a molecular mark for gene silencing memory.

J. Issa, J. Jelinek, M. Estecio, 2012, Cancer research.

Transcriptional Selectivity of Epigenetic Therapy in Cancer.

Xiaowei Chen, J. Issa, J. Jelinek, 2017, Cancer research.

Aberrant CpG island methylation in acute myeloid leukemia is accentuated at relapse.

J. Issa, J. Jelinek, Lanlan Shen, 2008, Blood.

Identification of Differentially Methylated Genes in Normal Prostate Tissues from African American and Caucasian Men

V. Apprey, J. Issa, J. Jelinek, 2010, Clinical Cancer Research.

Epigenetic synergy between decitabine and platinum derivatives

Xin Hu, J. Issa, J. Jelinek, 2015, Clinical Epigenetics.

Examination of Whole Blood DNA Methylation as a Potential Risk Marker for Gastric Cancer

J. Issa, J. Jelinek, W. Chung, 2013, Cancer Prevention Research.

Aberrant DNA Methylation Is Associated with Disease Progression, Resistance to Imatinib and Shortened Survival in Chronic Myelogenous Leukemia

Nianxiang Zhang, J. Issa, J. Jelinek, 2011, PloS one.

A phase I study of decitabine with pegylated interferon α-2b in advanced melanoma: impact on DNA methylation and lymphocyte populations

E. Plimack, P. Sharma, J. Issa, 2014, Investigational New Drugs.

G9a Is Essential for Epigenetic Silencing of K+ Channel Genes in Acute-to-Chronic Pain Transition

J. Issa, J. Jelinek, M. Cesaroni, 2015, Nature Neuroscience.

Genomic and epigenomic predictors of response to guadecitabine in relapsed/refractory acute myelogenous leukemia

J. Issa, J. Jelinek, W. Chung, 2019, Clinical Epigenetics.

DNA methylation entropy as a measure of stem cell replication and aging

J. Issa, J. Jelinek, J. Madzo, 2023, Genome Biology.

Epigenetic changes in estrogen receptor beta gene in atherosclerotic cardiovascular tissues and in-vitro vascular senescence.

J. Issa, J. Jelinek, P. Goldschmidt-Clermont, 2007, Biochimica et biophysica acta.

Impact of decitabine on immunohistochemistry expression of the putative tumor suppressor genes FHIT, WWOX, FUS1 and PTEN in clinical tumor samples

I. Wistuba, J. Issa, J. Jelinek, 2014, Clinical Epigenetics.

Disruption of ferroportin 1 regulation causes dynamic alterations in iron homeostasis and erythropoiesis in polycythaemia mice

J. Jelinek, J. Prchal, H. Youssoufian, 2004, Development.

Epigenetic control of PRV-1 expression on neutrophils.

J. Issa, J. Jelinek, J. Prchal, 2007, Experimental hematology.

Phase I study of azacitidine and oxaliplatin in patients with advanced cancers that have relapsed or are refractory to any platinum therapy

K. Hess, I. Wistuba, J. Issa, 2015, Clinical Epigenetics.

Impact of splice-site mutations of the human MDR1 cDNA on its stability and expression following retroviral gene transfer

J. Jelinek, M. Hildinger, C. Baum, 2003, Gene Therapy.

Derivative (6)t(1;6)(q22;p21) revealed in bone marrow cells by FISH 9 months before diagnosis of acute T-lymphoblastic leukemia.

J. Jelinek, Z. Zemanová, J. Březinová, 1996, Cancer Genetics and Cytogenetics.

Gestational high fat diet protects 3xTg offspring from memory impairments, synaptic dysfunction and brain pathology

J. Issa, J. Jelinek, E. Lauretti, 2019, Molecular Psychiatry.

Decreased efficacy of drugs targeting the vascular endothelial growth factor pathway by the epigenetic silencing of FLT1 in renal cancer cells

J. Jelinek, S. H. Lee, J. Kim, 2015, Clinical Epigenetics.

CpG Island Methylation Is a Poor Prognostic Factors in Myelodysplastic Syndrome Patients and Is Reversed by Decitabine Therapy-Results of a Phase III Randomized Study.

D. Berry, J. Issa, J. Jelinek, 2005 .

Chromatin remodeling gene SMARCA5 is dysregulated in primitive hematopoietic cells of acute leukemia

J. Jelinek, T. Stopka, E. Nečas, 2000, Leukemia.

Targeting Calcium Signaling Induces Epigenetic Reactivation of Tumor Suppressor Genes in Cancer.

S. Baylin, Ying Cui, J. Issa, 2016, Cancer Research.

DNA methylation entropy as a measure of stem cell replication and aging

J. Issa, J. Jelinek, J. Madzo, 2023, Genome Biology.

Concomitant JAK2 V617F‐positive polycythemia vera and B‐cell chronic lymphocytic leukemia in three patients originating from two separate hematopoietic stem cells

J. Jelinek, M. Jarošová, K. Indrák, 2013, American journal of hematology.

Folic Acid Supplementation Promotes Hypomethylation in Both the Inflamed Colonic Mucosa and Colitis-Associated Dysplasia

C. Sapienza, Yan Zhou, J. Jelinek, 2023, Cancers.

Hypomethylation Dynamics Following Decitabine Therapy in Chronic Myelogenous Leukemia.

J. Issa, J. Jelinek, H. Kantarjian, 2004 .

Decreased efficacy of drugs targeting the vascular endothelial growth factor pathway by the epigenetic silencing of FLT1 in renal cancer cells

J. Jelinek, H. Jeong, S. H. Lee, 2015, Clinical Epigenetics.

Tyrosine kinase inhibitor-induced defects in DNA repair sensitize FLT 3 ( ITD )-positive leukemia cells to PARP 1 inhibitors Short title : FLT 3 and PARP 1 inhibitors against AMLs

L. Bullinger, J. Jelinek, R. Płoski, 2018 .

e- Blood Methylation of AR locus does not always reﬂect X chromosome inactivation state

N. Agarwal, J. Jelinek, J. Prchal, 2012 .

In Vitro Expansion of Polycythemia Vera Progenitors Favors Expansion of Erythroid Precursors without JAK2 V617F Mutation.

J. Issa, J. Jelinek, J. Prchal, 2005 .

Abstract 4331: Potential role of the splicing factor SF3B1 in epigenetic regulation and activation of p53 signaling

J. Issa, J. Jelinek, Yasuyuki Okamoto, 2019, Molecular and Cellular Biology / Genetics.

Cloning and expression of murine hematopoietic specific chromatin remodeling gene SMARCA5

J. Jelinek, T. Stopka, R. Cmejla, 2000 .

Family with Bannayan-Riley-Ruvalcaba Syndrome: Linkage..

J. Jelinek, 2019 .

Near-tetraploid poorly differentiated acute myeloid leukemia M0 diagnosed by short-term cultures with a phorbol ester TPA.

A. Jirásek, J. Jelinek, J. Březinová, 1994, Leukemia research.

Digital Restriction Enzyme Analysis of Methylation (DREAM) by Next Generation Sequencing Yields High Resolution Maps of DNA Methylation.

J. Issa, J. Jelinek, M. Estecio, 2009 .

Abstract 5004: CpG island methylator phenotype in bladder cancer

Nianxiang Zhang, B. Czerniak, J. Issa, 2012 .

Partial trisomy of 3q detected by chromosome painting in a case of juvenile chronic myelomonocytic leukemia.

J. Jelinek, J. Wiegant, J. Starý, 1993, Cancer genetics and cytogenetics.

Ribosomal protein S19 gene mutations in patients with diamond-blackfan anemia and identification of ribosomal protein S19 pseudogenes.

J. Zavadil, J. Jelinek, V. Mihál, 2000, Blood cells, molecules & diseases.

TET1 and TDG suppress inflammatory response in intestinal tumorigenesis: implications for colorectal tumors with the CpG Island Methylator Phenotype.

V. Moreno, J. Issa, J. Jelinek, 2023, Gastroenterology.

Genome-wide identification of aberrantly methylated promoter associated CpG islands in acute lymphocytic leukemia

J. Issa, J. Jelinek, G. Garcia-Manero, 2008, Leukemia.

Demethylator phenotypes in acute myeloid leukemia

J. Issa, J. Jelinek, J. Madzo, 2018, Leukemia.

Methylome sequencing for fibrolamellar hepatocellular carcinoma depicts distinctive features

V. Paradis, J. Issa, J. Jelinek, 2015, Epigenetics.

Increased DNA Methylation Is Associated with Good Prognosis in AML.

J. Issa, J. Jelinek, S. Kornblau, 2007 .

Architecture of epigenetic reprogramming following Twist1-mediated epithelial-mesenchymal transition

J. Issa, J. Jelinek, Sendurai A Mani, 2013, Genome Biology.

Computed tomographic scan of the chest, latex agglutination test and plasma (1AE3)-beta-D-glucan assay in early diagnosis of invasive pulmonary aspergillosis: a prospective study of 215 patients

J. Jelinek, H. Kantarjian, Y. Kanda, 1994 .

Abstract 373: An siRNA screen identifies CHD4 as a target for epigenetic therapy

J. Issa, J. Jelinek, W. Chung, 2014 .

Mutations and promoter methylation status of NPM1 in myeloproliferative disorders

S. Chavali, A. Mahajan, D. Bharadwaj, 2000 .

Diverse genome‐wide DNA methylation alterations in canine hepatocellular tumours

J. Jelinek, M. Takiguchi, K. Aoshima, 2023, Veterinary medicine and science.

Decitabine effect on human tumor expression of various transporters.

I. Wistuba, J. Issa, J. Jelinek, 2016, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Analysis of epigenetic modifications by next generation sequencing

Hao Li, J. Issa, J. Jelinek, 2009, 2009 Annual International Conference of the IEEE Engineering in Medicine and Biology Society.

JAK2 mutation and disease phenotype: a double L611V/V617F in cis mutation of JAK2 is associated with isolated erythrocytosis and increased activation of AKT and ERK1/2 rather than STAT5

J. Issa, J. Jelinek, M. Boissinot, 2010, Leukemia.

Genetic Determinants of Response to Guadecitabine (SGI-110) in AML

J. Issa, J. Jelinek, W. Chung, 2016 .

Zebrafish embryos as a screen for DNA methylation modifications after compound exposure.

J. Pennings, J. Issa, J. Jelinek, 2016, Toxicology and applied pharmacology.

Targeting Calcium Signaling Induces Epigenetic Reactivation of Tumor Suppressor Genes in Cancer.

S. Baylin, Ying Cui, J. Issa, 2016, Cancer research.

Abstract 380: Discovery of new epigenetic drugs among FDA-approved drug libraries

S. Baylin, Ying Cui, J. Issa, 2014 .

DNA polymerase theta protects leukemia cells from metabolic-induced DNA damage.

G. Gupta, J. Jelinek, K. Matlawska-Wasowska, 2022, Blood.

Prognostic factors and risk assessment in chronic myelomonocytic leukemia: Validation study of the M.D. Anderson Prognostic Scoring System

J. Jelinek, Yu Shen, J. Cortes, 2007, Leukemia & lymphoma.