X. Guo

发表

Optimizing the medium perfusion rate in bone tissue engineering bioreactors

G. Vunjak‐Novakovic, M. Fröhlich, W. Grayson, 2011, Biotechnology and bioengineering.

High-Resolution Peripheral Quantitative Computed Tomography Can Assess Microstructural and Mechanical Properties of Human Distal Tibial Bone

X. Guo, Mark F Adams, E. Shane, 2009, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Behavior of intact and damaged honeycombs: a finite element study

L. Gibson, X. Guo, X.Edward Guo, 1999 .

Anatomically shaped osteochondral constructs for articular cartilage repair.

G. Ateshian, X. Guo, C. Hung, 2003, Journal of biomechanics.

Robust Trabecular Microstructure in Type 2 Diabetes Revealed by Individual Trabecula Segmentation Analysis of HR‐pQCT Images

X. Guo, M. Rubin, S. Silverberg, 2018, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Trabecular bone exhibits fully linear elastic behavior and yields at low strains.

T. McMahon, W. Hayes, X. Guo, 1994, Journal of biomechanics.

Elastic modulus and hardness of cortical and trabecular bone lamellae measured by nanoindentation in the human femur.

S. Goldstein, P. Zysset, X. Guo, 1999, Journal of biomechanics.

Trabecular plates and rods determine elastic modulus and yield strength of human trabecular bone.

X. Guo, T. Keaveny, Mark F Adams, 2015, Bone.

Abnormalities in cortical bone, trabecular plates, and stiffness in postmenopausal women treated with glucocorticoids.

X. Guo, E. Stein, D. McMahon, 2014, The Journal of clinical endocrinology and metabolism.

A MIXED FINITE ELEMENT FORMULATION OF TRIPHASIC MECHANO-ELECTROCHEMICAL THEORY FOR CHARGED, HYDRATED BIOLOGICAL SOFT TISSUES

V. Mow, W. Lai, X. Guo, 1999 .

Quantification of the Roles of Trabecular Microarchitecture and Trabecular Type in Determining the Elastic Modulus of Human Trabecular Bone

Paul Sajda, Punam K Saha, Felix W Wehrli, 2006, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Complete Volumetric Decomposition of Individual Trabecular Plates and Rods and Its Morphological Correlations With Anisotropic Elastic Moduli in Human Trabecular Bone

Paul Sajda, Punam K Saha, Felix W Wehrli, 2007, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Individual trabecula segmentation (ITS)–based morphological analysis of microscale images of human tibial trabecular bone at limited spatial resolution

X. Guo, E. Shane, X. S. Liu, 2011, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Mechanical behavior of damaged trabecular bone.

W C Hayes, T M Keaveny, W. Hayes, 1994, Journal of biomechanics.

Finite element modeling of damage accumulation in trabecular bone under cyclic loading.

W C Hayes, T M Keaveny, T. McMahon, 1994, Journal of biomechanics.

The dependence of transversely isotropic elasticity of human femoral cortical bone on porosity.

X Edward Guo, X. Guo, X. N. Dong, 2004, Journal of biomechanics.

Intracellular calcium waves in bone cell networks under single cell nanoindentation.

G. Whitesides, K. Costa, X. Guo, 2006, Molecular & cellular biomechanics : MCB.

Intercellular calcium wave propagation in linear and circuit-like bone cell networks

Bo Huo, X. Guo, Xin L. Lu, 2010, Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences.

In situ intracellular calcium oscillations in osteocytes in intact mouse long bones under dynamic mechanical loading

Erping Luo, X Edward Guo, Da Jing, 2014, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Influence of Vertical Trabeculae on the Compressive Strength of the Human Vertebra

Tony M Keaveny, X Edward Guo, X. Guo, 2010, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Study of post-yield behavior of trabecular bone using a 3-D microstructural model

S. Goldstein, P. Zysset, X. Guo, 1995 .

Mechanical consequence of trabecular bone loss and its treatment: a three-dimensional model simulation.

X. Guo, X E Guo, C. Kim, 2002, Bone.

Bone density, geometry, microstructure, and stiffness: Relationships between peripheral and central skeletal sites assessed by DXA, HR‐pQCT, and cQCT in premenopausal women

Adi Cohen, Thomas Lang, X Edward Guo, 2010, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

High-resolution peripheral quantitative computed tomography (HR-pQCT) can assess microstructural and biomechanical properties of both human distal radius and tibia: Ex vivo computational and experimental validations.

Tony M Keaveny, X Edward Guo, X. Guo, 2016, Bone.

Deterioration of trabecular plate-rod and cortical microarchitecture and reduced bone stiffness at distal radius and tibia in postmenopausal women with vertebral fractures.

X. Guo, E. Shane, E. Stein, 2016, Bone.

Spatiotemporal properties of intracellular calcium signaling in osteocytic and osteoblastic cell networks under fluid flow.

Paul Sajda, Erping Luo, X Edward Guo, 2013, Bone.

Osteocyte-viability-based simulations of trabecular bone loss and recovery in disuse and reloading

X. Guo, K. Hwang, X. S. Liu, 2014, Biomechanics and modeling in mechanobiology.

Tissue Engineered Bone Differentiated From Human Adipose Derived Stem Cells Inhibit Posterolateral Fusion in an Athymic Rat Model

Jonathan C. Bernhard, G. Vunjak‐Novakovic, L. Lenke, 2017, Spine.

Micromechanics of osteonal cortical bone fracture.

S A Goldstein, S. Goldstein, X. Guo, 1998, Journal of biomechanical engineering.

Quantification of trabecular bone microdamage using the virtual internal bond model and the individual trabeculae segmentation technique

X. Guo, X. S. Liu, B. Ji, 2010, Computer methods in biomechanics and biomedical engineering.

Bioactive Stratified Polymer Ceramic-Hydrogel Scaffold for Integrative Osteochondral Repair

Gerard A. Ateshian, Clark T. Hung, Jie Jiang, 2010, Annals of Biomedical Engineering.

Diffusion‐based MR methods for bone structure and evolution

T R Brown, T. Brown, X. Guo, 2008, Magnetic resonance in medicine.

In premenopausal women with idiopathic osteoporosis, lower bone formation rate is associated with higher body fat and higher IGF-1

X. Guo, Bin Zhao, E. Shane, 2021, Osteoporosis International.

Toughening mechanisms for the attachment of architectured materials: The mechanics of the tendon enthesis

Adam C. Abraham, G. Genin, X. Guo, 2021, bioRxiv.

Individual Trabeculae Segmentation (ITS)–Based Morphological Analysis of High-Resolution Peripheral Quantitative Computed Tomography Images Detects Abnormal Trabecular Plate and Rod Microarchitecture in Premenopausal Women With Idiopathic Osteoporosis

X. Guo, R. Recker, E. Shane, 2010, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Sustained Low-dose Dexamethasone Delivery Via a PLGA Microsphere-embedded Agarose Implant for Enhanced Osteochondral Repair.

G. Ateshian, X. Guo, C. Hung, 2019, Acta biomaterialia.

Mechanosensitive Ca2+ signaling and coordination is diminished in osteocytes of aged mice during ex vivo tibial loading

Matthew J. Silva, X. Guo, Samuel T. Robinson, 2020, Connective tissue research.

T-Type voltage-sensitive calcium channels mediate mechanically-induced intracellular calcium oscillations in osteocytes by regulating endoplasmic reticulum calcium dynamics.

X. Guo, P. L. Leong, Genevieve N. Brown, 2016, Bone.

A Trabecular Bone Explant Model of Osteocyte–Osteoblast Co-Culture for Bone Mechanobiology

X. Guo, R. Guldberg, Helen H. Lu, 2009, Cellular and Molecular Bioengineering.

Title Excessive Activation of TGF β by Spinal Instability CausesVertebral Endplate Sclerosis

L. Riley, X. Guo, Amit Jain, 2016 .

Efficacy of serotonin inhibition in mouse models of bone loss

X. Guo, G. Karsenty, V. Yadav, 2011, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Tissue-Engineered Model of Human Osteolytic Bone Tumor.

G. Vunjak‐Novakovic, X. Guo, A. Villasante, 2017, Tissue engineering. Part C, Methods.

Indentation Determined Mechanoelectrochemical Properties and Fixed Charge Density of Articular Cartilage

V. Mow, W. Lai, X. Guo, 2004, Annals of Biomedical Engineering.

Dependence of mechanical properties of trabecular bone on plate-rod microstructure determined by individual trabecula segmentation (ITS).

X. Guo, X. S. Liu, A. Fields, 2014, Journal of biomechanics.

Subchondral Trabecular Rod Loss and Plate Thickening in the Development of Osteoarthritis

X. Guo, F. Leung, E. Shane, 2018, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Human Serum Enhances Biomimicry of Engineered Tissue Models of Bone and Cancer

Andrew R. Cohen, G. Vunjak‐Novakovic, A. Cohen, 2021, Frontiers in Bioengineering and Biotechnology.

Effects of low intensity vibration on bone and muscle in rats with spinal cord injury

X. Guo, H. Bramlett, W. Bauman, 2014, Osteoporosis International.

Fast Trabecular Bone Strength Predictions of HR‐pQCT and Individual Trabeculae Segmentation–Based Plate and Rod Finite Element Model Discriminate Postmenopausal Vertebral Fractures

X. Guo, Mark F Adams, E. Shane, 2013, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Skeletal microstructural abnormalities in postmenopausal women with chronic obstructive pulmonary disease

X. Guo, D. Kimmel, Hua Zhou, 2010, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Bone density, microarchitecture and stiffness in Caucasian and Caribbean Hispanic postmenopausal American women

X. Guo, E. Shane, T. Nickolas, 2014, Bone Research.

Skeletal Microstructure and Estimated Bone Strength Improve Following Parathyroidectomy in Primary Hyperparathyroidism

X. Guo, M. Rubin, J. Bilezikian, 2018, The Journal of clinical endocrinology and metabolism.

Proteoglycans and Mechanical Behavior of Condylar Cartilage

V. Mow, X. Guo, X. L. Lu, 2009, Journal of dental research.

Premenopausal and postmenopausal differences in bone microstructure and mechanical competence in Chinese‐American and white women

X. Guo, J. Bilezikian, X. S. Liu, 2013, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Individual trabecula segmentation (ITS)‐based morphological analyses and microfinite element analysis of HR‐pQCT images discriminate postmenopausal fragility fractures independent of DXA measurements

X. Guo, E. Shane, T. Nickolas, 2012, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Maternal vitamin B12 in mice positively regulates bone, but not muscle mass and strength in post-weaning and mature offspring

X. Guo, V. Yadav, Parminder Singh, 2021, American journal of physiology. Regulatory, integrative and comparative physiology.

Intervention timing of strontium treatment on estrogen depletion‐induced osteoporosis in rats: Bone microstructure and mechanics

X. Guo, W. Lu, K. Luk, 2014, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

The Verification of a Novel Explant System Used to Determine the Role of Osteocytes in the Breast Cancer Vicious Cycle

X. Guo, S. Bansal, Genevieve N. Brown, 2020 .

Sexual Dimorphism in Cortical and Trabecular Bone Microstructure Appears During Puberty in Chinese Children

X. Guo, J. Cheng, E. Seeman, 2018, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Distinct Tissue Mineral Density in Plate‐ and Rod‐like Trabeculae of Human Trabecular Bone

X. Guo, G. Kazakia, Ji Wang, 2015, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

A trabecular plate-like phenotype is overrepresented in Chinese-American versus Caucasian women

X. Guo, J. Russo, J. Bilezikian, 2014, Osteoporosis International.

Skeletal Structure in Postmenopausal Women With Osteopenia and Fractures Is Characterized by Abnormal Trabecular Plates and Cortical Thinning

X. Guo, E. Shane, T. Nickolas, 2014, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Accuracy of individual trabecula segmentation based plate and rod finite element models in idealized trabecular bone microstructure.

X. Guo, K. Hwang, X. S. Liu, 2013, Journal of biomechanical engineering.

Better skeletal microstructure confers greater mechanical advantages in Chinese‐American women versus white women

X. Guo, J. Bilezikian, X. S. Liu, 2011, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Tissue engineered autologous cartilage-bone grafts for temporomandibular joint regeneration

Krista M. Durney, Mandi J. Lopez, Olaia F. Vila, 2020, Science Translational Medicine.

Localization and Distribution of Cartilage Oligomeric Matrix Protein in the Rat Intervertebral Disc

X. Guo, C. Hung, F. Chen, 2006, Spine.

The MAPK Erk5 is necessary for proper skeletogenesis involving a Smurf-Smad-Sox9 molecular axis

K. Kaneda, X. Guo, Kakeru Ozaki, 2018, Development.

Chinese Women in Both the United States and Hong Kong Have Cortical Microstructural Advantages and More Trabecular Plates Compared With White Women

X. Guo, J. Bilezikian, L. Qin, 2019, JBMR plus.

Geometric determinants to cement line debonding and osteonal lamellae failure in osteon pushout tests.

X. Guo, X. N. Dong, 2004, Journal of biomechanical engineering.

Spreading area and shape regulate apoptosis and differentiation of osteoblasts

G. Song, X. Guo, Qi Liu, 2013, Biomedical Materials.

Effect of Low Vitamin D on Volumetric Bone Mineral Density, Bone Microarchitecture, and Stiffness in Primary Hyperparathyroidism.

X. Guo, S. Silverberg, K. Nishiyama, 2016, The Journal of clinical endocrinology and metabolism.

Fixed negative charges modulate mechanical behaviours and electrical signals in articular cartilage under unconfined compression — a triphasic paradigm

V. Mow, W. Lai, X. Guo, 2002 .

Serotonin reuptake inhibitors act centrally to cause bone loss in mice by counteracting a local antiresorptive effect

J. Mann, X. Guo, P. Ducy, 2016, Nature Medicine.

A neuronal action of sirtuin 1 suppresses bone mass in young and aging mice

X. Guo, B. Bisikirska, S. Kousteni, 2022, The Journal of clinical investigation.

A Neuronal Action of Sirtuin 1 Suppresses Bone Mass in and Aging Mice

X. Guo, B. Bisikirska, S. Kousteni, 2022 .

Immune response and effect of adenovirus-mediated human BMP-2 gene transfer on the repair of segmental tibial bone defects in goats

X. Guo, J. Lou, K. Dai, 2005, Acta orthopaedica.

Fluid Flow Induced Calcium Response in Bone Cell Network

Qiaobing Xu, George M Whitesides, Kevin D Costa, 2008, Cellular and molecular bioengineering.

Early zoledronate treatment inhibits subchondral bone microstructural changes in skeletally-mature, ACL-transected canine knees.

X. Guo, W. Lu, Y. Hu, 2022, Bone.

The cross-talk between osteoclasts and osteoblasts in response to strontium treatment: involvement of osteoprotegerin.

X. Guo, W. Lu, K. Luk, 2011, Bone.

Excessive Activation of TGFβ by Spinal Instability Causes Vertebral Endplate Sclerosis

L. Riley, X. Guo, Amit Jain, 2016, Scientific Reports.

Pharmacological inhibition of gut-derived serotonin synthesis is a potential bone anabolic treatment for osteoporosis.

M. Vidal, J. Mann, X. Guo, 2010, Nature medicine.

Dynamic simulation of three dimensional architectural and mechanical alterations in human trabecular bone during menopause.

Baohua Ji, Paul Sajda, X Edward Guo, 2008, Bone.

Multiple myeloma-derived MMP-13 mediates osteoclast fusogenesis and osteolytic disease.

S. Weiss, X. Guo, G. Roodman, 2016, The Journal of clinical investigation.

Trabecular Bone Response to Mechanical and Parathyroid Hormone Stimulation: The Role of Mechanical Microenvironment

X. Guo, R. Müller, Hua Zhou, 2003, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Calcium Concentration Effects on the Mechanical and Biochemical Properties of Chondrocyte-Alginate Constructs

Leo Q Wan, Van C Mow, Jie Jiang, 2008, Cellular and molecular bioengineering.

Bariatric surgery results in cortical bone loss.

X. Guo, M. Bessler, E. Stein, 2013, The Journal of clinical endocrinology and metabolism.

Mechano-electrochemical properties of articular cartilage: their inhomogeneities and anisotropies.

X. Edward Guo, V. Mow, X. Guo, 2002, Annual review of biomedical engineering.

In vivo evaluation of a multiphased scaffold designed for orthopaedic interface tissue engineering and soft tissue-to-bone integration.

Stephen B Doty, Jeffrey P Spalazzi, X Edward Guo, 2008, Journal of biomedical materials research. Part A.

Engineering anatomically shaped human bone grafts

X. Sherry Liu, Warren L. Grayson, Gordana Vunjak-Novakovic, 2009, Proceedings of the National Academy of Sciences.

The generalized triphasic correspondence principle for simultaneous determination of the mechanical properties and proteoglycan content of articular cartilage by indentation.

V. Mow, X. Guo, F. Chen, 2007, Journal of biomechanics.

A linearized formulation of triphasic mixture theory for articular cartilage, and its application to indentation analysis.

V. Mow, X. Guo, L. Wan, 2010, Journal of biomechanics.

Fixed electrical charges and mobile ions affect the measurable mechano-electrochemical properties of charged-hydrated biological tissues: the articular cartilage paradigm.

V. Mow, X. Guo, L. Wan, 2004, Mechanics & chemistry of biosystems : MCB.

The influence of the fixed negative charges on mechanical and electrical behaviors of articular cartilage under unconfined compression.

W M Lai, V C Mow, V. Mow, 2004, Journal of Biomechanical Engineering.

Genetic determination of the cellular basis of the sympathetic regulation of bone mass accrual

X. Guo, G. Karsenty, E. Hinoi, 2011, The Journal of Cell Biology.

Signaling through the M(3) muscarinic receptor favors bone mass accrual by decreasing sympathetic activity.

J. Wess, X. Guo, X. S. Liu, 2010, Cell metabolism.

Combined finite element (FE) modeling and fluid shear experiment to determine the viscoelastic material properties of osteocytes

X. Guo, Z. Zhuang, A. Baik, 2010, Proceedings of the 2010 IEEE 36th Annual Northeast Bioengineering Conference (NEBEC).

miR-34s inhibit osteoblast proliferation and differentiation in the mouse by targeting SATB2

X. Guo, R. Grosschedl, G. Karsenty, 2012, The Journal of cell biology.

miR-34 s inhibit osteoblast proliferation and differentiation in the mouse by targeting SATB 2

X. Guo, R. Grosschedl, G. Karsenty, 2022 .

Mechanical stress determines the configuration of TGFβ activation in articular cartilage

X. Guo, T. Ha, Jessie Huang, 2021, Nature Communications.

Dissociation of the neuronal regulation of bone mass and energy metabolism by leptin in vivo

X. Guo, X. S. Liu, G. Karsenty, 2008, Proceedings of the National Academy of Sciences.

Inhibition of gut-derived serotonin synthesis: a potential bone anabolic treatment

M. Vidal, J. Mann, X. Guo, 2010, Nature Medicine.

Matrix deposition modulates the viscoelastic shear properties of hydrogel-based cartilage grafts.

V. Mow, X. Guo, Helen H. Lu, 2011, Tissue engineering. Part A.

A triphasic orthotropic laminate model for cartilage curling behavior: fixed charge density versus mechanical properties inhomogeneity.

Leo Q Wan, Van C Mow, X Edward Guo, 2010, Journal of biomechanical engineering.

The effect of matrix tension-compression nonlinearity and fixed negative charges on chondrocyte responses in cartilage.

Van C Mow, X Edward Guo, V. Mow, 2005, Molecular & cellular biomechanics : MCB.

An Exact Theoretical Solution for Predicting the Apparent Poisson’s Ratio of Articular Cartilage: A Charged-Hydrated Biological Tissue — The Triphasic Paradigm

V. Mow, X. Guo, L. Wan, 2004 .

FOXO1 orchestrates the bone-suppressing function of gut-derived serotonin.

R. DePinho, R. Hen, X. Guo, 2012, The Journal of clinical investigation.

Primary hyperparathyroidism is associated with abnormal cortical and trabecular microstructure and reduced bone stiffness in postmenopausal women

S. Cremers, X. Guo, E. Shane, 2013, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Fusobacterium nucleatum secretes amyloid‐like FadA to enhance pathogenicity

Luke E. Berchowitz, X. Guo, P. Papapanou, 2021, EMBO reports.

A Serotonin-Dependent Mechanism Explains the Leptin Regulation of Bone Mass, Appetite, and Energy Expenditure

Kenji F. Tanaka, R. Hen, J. Mann, 2009, Cell.

Establishing Biomechanical Mechanisms in Mouse Models: Practical Guidelines for Systematically Evaluating Phenotypic Changes in the Diaphyses of Long Bones

Deepak Vashishth, Karl J Jepsen, Matthew J Silva, 2015, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Abnormal Skeletal Strength and Microarchitecture in Women With Celiac Disease.

Suzanne K. Lewis, X. Guo, E. Shane, 2015, The Journal of clinical endocrinology and metabolism.

Unique local bone tissue characteristics in iliac crest bone biopsy from adolescent idiopathic scoliosis with severe spinal deformity

X. Guo, Y. Qiu, Y. E. Yu, 2017, Scientific Reports.

Adults with cystic fibrosis have deficits in bone structure and strength at the distal tibia despite similar size and measuring standard and relative sites.

X. Guo, E. Shane, S. Agarwal, 2018, Bone.

Mechanically induced Ca2+ oscillations in osteocytes release extracellular vesicles and enhance bone formation

Rachel L. Sattler, L. Bonewald, X. Guo, 2018, Bone Research.

Abnormal subchondral bone remodeling and its association with articular cartilage degradation in knees of type 2 diabetes patients

Qingjun Wei, X. Guo, F. Leung, 2017, Bone Research.

The MAPK Erk5 is necessary for proper skeletogenesis involving a Smurf-Smad-Sox9 molecular axis

K. Kaneda, X. Guo, Kakeru Ozaki, 2018, Development.

Osteoprotegerin deficiency attenuates strontium‐mediated inhibition of osteoclastogenesis and bone resorption

K. Luk, X. Guo, W. Lu, 2011, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Genetic determination of the cellular basis of the sympathetic regulation of bone mass accrual

Bin Zhou, X. Guo, G. Karsenty, 2011, The Journal of experimental medicine.

Abnormal microarchitecture and stiffness in postmenopausal women using chronic inhaled glucocorticoids

X. Guo, E. Shane, E. Stein, 2018, Osteoporosis International.

Bone Structure and Function

X. Guo, Y. Hu, A. Dinescu, 2020, Encyclopedia of Bone Biology.

Spatially Varying Material Properties of the Rat Caudal Intervertebral Disc

G. Ateshian, X. Guo, C. Hung, 2006, Spine.

Osteocyte Mechanosensing following short-term and long-term treatment with Sclerostin antibody.

X. Guo, H. Ke, Samuel T. Robinson, 2021, Bone.

Geometric control of human stem cell morphology and differentiation.

Gordana Vunjak-Novakovic, Warren L Grayson, Leo Q Wan, 2010, Integrative biology : quantitative biosciences from nano to macro.

Adiponectin regulates bone mass via opposite central and peripheral mechanisms through FoxO1.

R. DePinho, J. Mann, Y. Hannun, 2013, Cell metabolism.

Osteoblast Elastic Modulus Measured by Atomic Force Microscopy Is Substrate Dependent

Kevin D. Costa, Clark T. Hung, K. Costa, 2005, Annals of Biomedical Engineering.

Spatiotemporal Distribution of Linear Microcracks and Diffuse Microdamage Following Daily Bouts of Fatigue Loading of Rat Ulnae

X. Guo, Jing Wang, Kangning Xie, 2019, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

Noninvasive Assessment of Skeletal Microstructure and Estimated Bone Strength in Hypoparathyroidism

X. Guo, M. Rubin, J. Bilezikian, 2016, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Kidney transplantation with early corticosteroid withdrawal: paradoxical effects at the central and peripheral skeleton.

S. Cremers, X. Guo, E. Shane, 2014, Journal of the American Society of Nephrology : JASN.

In Vivo μMRI‐Based Finite Element and Morphological Analyses of Tibial Trabecular Bone in Eugonadal and Hypogonadal Men Before and After Testosterone Treatment

Felix W Wehrli, Branimir Vasilic, Chamith S Rajapakse, 2008, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Osteocyte Viability and Regulation of Osteoblast Function in a 3D Trabecular Bone Explant Under Dynamic Hydrostatic Pressure

X. Guo, C. Hung, R. Mauck, 2004, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

CREB mediates brain serotonin regulation of bone mass through its expression in ventromedial hypothalamic neurons.

L. Tecott, X. Guo, A. Means, 2010, Genes & development.

Prediction of cortical bone elastic constants by a two-level micromechanical model using a generalized self-consistent method.

X. Guo, X. N. Dong, X. Guo, 2006, Journal of biomechanical engineering.

A generalized self-consistent estimate for the effective elastic moduli of fiber-reinforced composite materials with multiple transversely isotropic inclusions

X. Guo, Yonggang Huang, X. N. Dong, 2005 .

Bone loss or lost bone: Rationale and recommendations for the diagnosis and treatment of early postmenopausal bone loss

S. Silverman, X. Guo, C. Turner, 2009, Current osteoporosis reports.

Electrical stimulation of hindlimb skeletal muscle has beneficial effects on sublesional bone in a rat model of spinal cord injury.

X. Guo, J. Jarvis, Jian Q. Feng, 2020, Bone.

Abdominal fat is associated with lower bone formation and inferior bone quality in healthy premenopausal women: a transiliac bone biopsy study.

Binsheng Zhao, S. Cremers, X. Guo, 2013, The Journal of clinical endocrinology and metabolism.

Advanced tools for tissue engineering: scaffolds, bioreactors, and signaling.

Farshid Guilak, David Kaplan, Milica Radisic, 2006, Tissue engineering.

Implications of noise and resolution on mechanical properties of trabecular bone estimated by image‐based finite‐element analysis

Jeremy Magland, Felix W Wehrli, Chamith S Rajapakse, 2009, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

Recapitulation of physiological spatiotemporal signals promotes in vitro formation of phenotypically stable human articular cartilage

Jonathan C. Bernhard, G. Vunjak‐Novakovic, X. Guo, 2017, Proceedings of the National Academy of Sciences.

Bone turnover and articular cartilage differences localized to subchondral cysts in knees with advanced osteoarthritis.

X. Guo, W. Lu, F. Leung, 2015, Osteoarthritis and cartilage.

Differences in bone microarchitecture between postmenopausal Chinese‐American and white women

Emily Stein, X Edward Guo, X. Guo, 2011, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Assessment of trabecular and cortical architecture and mechanical competence of bone by high-resolution peripheral computed tomography: comparison with transiliac bone biopsy

X. Guo, R. Müller, R. Recker, 2009, Osteoporosis International.

An application of nanoindentation technique to measure bone tissue Lamellae properties.

Philippe K Zysset, Steven A Goldstein, X Edward Guo, 2005, Journal of biomechanical engineering.

The functional environment of chondrocytes within cartilage subjected to compressive loading: a theoretical and experimental approach.

V. Mow, G. Ateshian, X. Guo, 2002, Biorheology.

Accurate and Efficient Plate and Rod Micro Finite Element Whole Bone Models Based on High-Resolution Peripheral Computed Tomography.

X. Guo, T. Keaveny, E. Shane, 2019, Journal of biomechanical engineering.

Quantification of a rat tail vertebra model for trabecular bone adaptation studies.

X. Guo, C. Kim, E. Takai, 2002, Journal of biomechanics.

Metformin Hydrochloride Encapsulation by Alginate Strontium Hydrogel for Cartilage Regeneration by Reliving Cellular Senescence.

X. Guo, W. Lu, Jun Huang, 2021, Biomacromolecules.

Simultaneous tracking of 3D actin and microtubule strains in individual MLO-Y4 osteocytes under oscillatory flow.

E. Hillman, X. Guo, A. Baik, 2013, Biochemical and biophysical research communications.

Mechanical Stimulation of Tissue Repair in the Hydraulic Bone Chamber

R E Guldberg, S A Goldstein, S J Hollister, 1997, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Microstructure Determines Apparent‐Level Mechanics Despite Tissue‐Level Anisotropy and Heterogeneity of Individual Plates and Rods in Normal Human Trabecular Bone

X. Guo, Y. Hu, Ji Wang, 2021, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Micromechanical analyses of vertebral trabecular bone based on individual trabeculae segmentation of plates and rods.

Paul Sajda, Tony M Keaveny, X Edward Guo, 2009, Journal of biomechanics.

Cellular and Molecular Bioengineering: A Tipping Point

Ning Wang, Cheng Dong, X. Edward Guo, 2012, Cellular and molecular bioengineering.

In Vitro Model of Vascularized Bone: Synergizing Vascular Development and Osteogenesis

Rui L. Reis, Rui A. Sousa, Warren L. Grayson, 2011, PloS one.

The Role of Biomechanics in Functional Tissue Engineering for Articular Cartilage

V. Mow, X. Guo, Helen H. Lu, 2003 .

THE MECHANO-ELECTROCHEMICAL ENVIRONMENT OF CHONDROCYTES IN ARTICULAR CARTILAGE EXPLANTS UNDER UNCONFINED COMPRESSION : EMPHASIS ON THE CELL-MATRIX INTERACTIONS

V. Mow, W. Lai, X. Guo, 2022 .

Lower Cortical Porosity and Higher Tissue Mineral Density in Chinese American Versus White Women

X. Guo, J. Bilezikian, X. S. Liu, 2014, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Accuracy of high‐resolution in vivo micro magnetic resonance imaging for measurements of microstructural and mechanical properties of human distal tibial bone

Paul Sajda, Jeremy Magland, Felix W Wehrli, 2010, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Efficient 3D rigid-body registration of micro-MR and micro-CT trabecular bone images

Felix W. Wehrli, Jeremy F. Magland, X. E. Guo, 2008, SPIE Medical Imaging.

Analysis of microstructural and mechanical alterations of trabecular bone in a simulated three-dimensional remodeling process.

Baohua Ji, Yonggang Huang, X Edward Guo, 2012, Journal of biomechanics.

Osteocytic network is more responsive in calcium signaling than osteoblastic network under fluid flow

X. Guo, X. Lu, B. Huo, 2012, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

A new fracture assessment approach coupling HR-pQCT imaging and fracture mechanics-based finite element modeling.

X. Guo, Bin Zhou, A. Ural, 2013, Journal of biomechanics.

Central QCT reveals lower volumetric BMD and stiffness in premenopausal women with idiopathic osteoporosis, regardless of fracture history.

X. Guo, R. Recker, D. Dempster, 2012, The Journal of clinical endocrinology and metabolism.

Advanced Structural Assessment of Bone Using CT and MRI

Felix W. Wehrli, X. Edward Guo, X. Sherry Liu, 2010 .

Bone microarchitecture and stiffness in premenopausal women with idiopathic osteoporosis.

X. Guo, R. Recker, E. Shane, 2009, The Journal of clinical endocrinology and metabolism.

Computational biomechanics of the distal tibia from high-resolution MR and micro-CT images.

Jeremy F Magland, Felix W Wehrli, Chamith S Rajapakse, 2010, Bone.

Substrate modulation of osteoblast adhesion strength, focal adhesion kinase activation, and responsiveness to mechanical stimuli.

X. Guo, C. Hung, R. Landesberg, 2006, Molecular & cellular biomechanics : MCB.

In vivo assessment of bone structure and estimated bone strength by first- and second-generation HR-pQCT

X. Guo, E. Shane, D. McMahon, 2016, Osteoporosis International.

Abnormal Microarchitecture and Reduced Stiffness at the Radius and Tibia in Postmenopausal Women With Fractures

X. Guo, E. Shane, T. Nickolas, 2010, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Abnormal microarchitecture and stiffness in postmenopausal women with ankle fractures.

X. Guo, E. Shane, T. Nickolas, 2011, The Journal of clinical endocrinology and metabolism.

Effects of trabecular type and orientation on microdamage susceptibility in trabecular bone.

G. Niebur, X. Guo, X. S. Liu, 2010, Bone.

Teriparatide Followed by Denosumab in Premenopausal Idiopathic Osteoporosis: Bone Microstructure and Strength by HR‐pQCT

X. Guo, R. Recker, E. Shane, 2022, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Experimental studies of bone mechanoadaptation: bridging in vitro and in vivo studies with multiscale systems

X. Edward Guo, Genevieve N. Brown, Rachel L. Sattler, 2016, Interface Focus.

Effects of thresholding techniques on microCT-based finite element models of trabecular bone.

Ralph Müller, Chi Hyun Kim, George Mikhail, 2007, Journal of biomechanical engineering.

Calcium response in osteocytic networks under steady and oscillatory fluid flow.

X. Guo, Miri Park, X. Lu, 2012, Bone.

Quasi-3D cytoskeletal dynamics of osteocytes under fluid flow.

Cheng Dong, Elizabeth M C Hillman, X Edward Guo, 2010, Biophysical journal.

Implications of resolution and noise for in vivo micro-MRI of trabecular bone.

Jeremy F Magland, Felix W Wehrli, Branimir Vasilic, 2008, Medical physics.

Contributions of trabecular rods of various orientations in determining the elastic properties of human vertebral trabecular bone.

X Edward Guo, X. Guo, X. S. Liu, 2007, Bone.

Teriparatide increases strength of the peripheral skeleton in premenopausal women with idiopathic osteoporosis: a pilot HR-pQCT study.

X. Guo, R. Recker, D. Dempster, 2014, The Journal of clinical endocrinology and metabolism.

Administration of High-Dose Methylprednisolone Worsens Bone Loss after Acute Spinal Cord Injury in Rats

X. Guo, W. Bauman, W. Qin, 2021, Neurotrauma reports.

Rapid bone loss occurs as early as 2 days after complete spinal cord transection in young adult rats

X. Guo, W. Bauman, W. Qin, 2019, Spinal Cord.

An ATP-dependent mechanism mediates intercellular calcium signaling in bone cell network under single cell nanoindentation.

K. Costa, X. Guo, Qiaobing Xu, 2010, Cell calcium.

Regional Variations of HR-pQCT Morphological and Biomechanical Measurements of the Distal Radius and Tibia and Their Associations with Whole Bone Mechanical Properties.

X. Guo, T. Keaveny, E. Shane, 2019, Journal of biomechanical engineering.

Microarchitectural abnormalities are more severe in postmenopausal women with vertebral compared to nonvertebral fractures.

X. Guo, E. Shane, T. Nickolas, 2012, Journal of Clinical Endocrinology and Metabolism.

Electrical signals for chondrocytes in cartilage.

W M Lai, V C Mow, G A Ateshian, 2002, Biorheology.

A noninvasive approach to determine viscoelastic properties of an individual adherent cell under fluid flow.

E. Hillman, X. Guo, Z. Zhuang, 2014, Journal of biomechanics.

Theoretical Analysis of Novel Quasi-3D Microscopy of Cell Deformation

E. Hillman, X. Guo, Z. Zhuang, 2012, Cellular and molecular bioengineering.

Mechanical Inputs to Bone Cells

X. Guo, Samuel T. Robinson, P. Shyu, 2020 .

Creep contributes to the fatigue behavior of bovine trabecular bone.

T. McMahon, W. Hayes, L. Gibson, 1998, Journal of biomechanical engineering.

In vivo precision of digital topological skeletonization based individual trabecula segmentation (ITS) analysis of trabecular microstructure at the distal radius and tibia by HR-pQCT

Bin Zhou, Ji Wang, Zhendong Zhang, 2016, Pattern Recognit. Lett..

Relationships between the stiffness of peripheral and central skeletal sites assessed by HR-pQCT- and cQCT-based finite element analysis

X. Guo, R. Recker, E. Shane, 2010, Proceedings of the 2010 IEEE 36th Annual Northeast Bioengineering Conference (NEBEC).

Mechanical properties of human trabecular bone lamellae quantified by nanoindentation.

S A Goldstein, S. Goldstein, P. Zysset, 1998, Technology and health care : official journal of the European Society for Engineering and Medicine.

Evaluation of bone microstructural properties: effect of testing conditions, depth, repetition, time delay and displacement rate

S. Goldstein, P. Zysset, X. Guo, 1997 .

Vertebral trabecular bone microscopic tissue elastic modulus and hardness do not change in ovariectomized rats

S A Goldstein, S. Goldstein, X. Guo, 2000, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

Osteocyte-viability-based simulations of trabecular bone loss and recovery in disuse and reloading

X. Guo, K. Hwang, X. S. Liu, 2014, Biomechanics and modeling in mechanobiology.

An Exploration of Cell Stress and Deformation Under Shear Flow

X. Guo, Xiaodong Wang, E. Takai, 2001, Advances in Bioengineering.

Interfacial strength of cement lines in human cortical bone.

X. Guo, X. N. Dong, Xiaohui Zhang, 2005, Mechanics & chemistry of biosystems : MCB.

Commonality in the microarchitecture of trabecular bone: A preliminary study.

A. Roy, X. Guo, Xiaodun Wang, 2018, Bone.

Trabecular Plate Loss and Deteriorating Elastic Modulus of Femoral Trabecular Bone in Intertrochanteric Hip Fractures

X. Guo, C. Thomas, J. Clement, 2013, Bone Research.

Type and orientation of yielded trabeculae during overloading of trabecular bone along orthogonal directions.

G. Niebur, X. Guo, X. S. Liu, 2010, Journal of biomechanics.

Three-dimensional rendering of trabecular bone microarchitecture using a probabilistic approach

Xiaodu Wang, Pengwei Xiao, Matthew Kirby, 2020, Biomechanics and modeling in mechanobiology.

Three-dimensional rendering of trabecular bone microarchitecture using a probabilistic approach

X. Guo, Xiaodun Wang, Y. Hu, 2020, Biomechanics and Modeling in Mechanobiology.

Abnormal microarchitecture and stiffness in postmenopausal women with isolated osteoporosis at the 1/3 radius.

X. Guo, E. Shane, E. Stein, 2019, Bone.

Spatiotemporal characterization of microdamage accumulation and its targeted remodeling mechanisms in diabetic fatigued bone

X. Guo, Wei Li, Kangning Xie, 2019, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Mic.romechanics of Osteonal

S. Goldstein, X. Guo, L. C. Liang, 2011 .

Understanding cement line interface in bone tissue: a linear fracture mechanics approach

S. Goldstein, X. Guo, M. He, 1995 .

miR-34s inhibit osteoblast proliferation and differentiation in the mouse by targeting SATB2

X. Guo, R. Grosschedl, G. Karsenty, 2012, The Journal of cell biology.

SBC 2009-206524 A SEMI-3 D REAL-TIME IMAGING TECHNIQUE FOR MEASURING BONE CELL DEFORMATION UNDER FLUID FLOW

X. Guo, X. S. Liu, X. Lu, 2009 .

Fast 3D registration of multimodality tibial images with significant structural mismatch

Michael J. Wald, Felix W. Wehrli, Jeremy F. Magland, 2009, Medical Imaging.

The impact of biomechanics in tissue engineering and regenerative medicine.

Robert L Sah, Cato T Laurencin, Robert E Guldberg, 2009, Tissue engineering. Part B, Reviews.

The MAPK Erk5 is necessary for proper skeletogenesis through a molecular axis that involves Smurfs-Smads-Sox9

K. Kaneda, X. Guo, Kakeru Ozaki, 2018 .

Quasi-3D cytoskeletal dynamics of osteocytes under fluid flow.

E. Hillman, X. Guo, X. Lu, 2010, Biophysical journal.

A linearized formulation of triphasic mixture theory for articular cartilage, and its application to indentation analysis.

V. Mow, X. Guo, L. Wan, 2010, Journal of biomechanics.

Bone turnover and articular cartilage differences localized to subchondral cysts in knees with advanced osteoarthritis.

X. Guo, F. Leung, H. Pan, 2015, Osteoarthritis and cartilage.