N. Surolia

发表

Identification, Characterization, and Inhibition of Plasmodium falciparum β-Hydroxyacyl-Acyl Carrier Protein Dehydratase (FabZ)*

S. Sharma, M. Kapoor, T. Ramya, 2003, Journal of Biological Chemistry.

de novo biosynthesis of heme offers a new chemotherapeutic target in the human malarial parasite.

G. Padmanaban, N. Surolia, Govindarajan Padmanaban, 1992, Biochemical and biophysical research communications.

Triclosan offers protection against blood stages of malaria by inhibiting enoyl-ACP reductase of Plasmodium falciparum

N. Surolia, A. Surolia, 2001, Nature Medicine.

Partial molar volumes of acyl carrier proteins are related to their states of acylation.

Rahul Modak, N. Surolia, A. Surolia, 2009, Biochemical and Biophysical Research Communications - BBRC.

15-deoxyspergualin inhibits eukaryotic protein synthesis through eIF2alpha phosphorylation.

T. Ramya, N. Surolia, A. Surolia, 2007, The Biochemical journal.

Structural Analysis of PfSec62-Autophagy Interacting Motifs (AIM) and PfAtg8 Interactions for Its Implications in RecovER-phagy in Plasmodium falciparum

N. Surolia, A. Mamidi, Ananya Ray, 2019, Front. Bioeng. Biotechnol..

Receptor-mediated targeting of toxins to intraerythrocytic parasite Plasmodium falciparum. surolia@jncasr.ac.in.

N. Surolia, 2000, Advanced drug delivery reviews.

Fluorescence polarization as a tool to study lectin-sugar interaction

N. Surolia, A. Surolia, M. I. Khan, 1983, Journal of Biosciences.

Plasticity in the Primary Binding Site of Galactose/N-Acetylgalactosamine-specific Lectins

Aditi Gupta, N. Surolia, A. Surolia, 2000, The Journal of Biological Chemistry.

Surface Plasmon Resonance Studies Resolve the Enigmatic Endotoxin Neutralizing Activity of Polymyxin B*

N. Surolia, A. Surolia, C. Thomas, 1999, The Journal of Biological Chemistry.

Polymyxin B: an ode to an old antidote for endotoxic shock.

N. Surolia, A. Surolia, V. Bhor, 2005, Molecular bioSystems.

Structural Insights into the Acyl Intermediates of the Plasmodium falciparum Fatty Acid Synthesis Pathway

N. Surolia, A. Surolia, A. Misra, 2009, The Journal of Biological Chemistry.

On the relationship of thermodynamic parameters with the buried surface area in protein-ligand complex formation

N. Surolia, A. Surolia, N. Singha, 1996, Bioscience reports.

Autophagy Underlies the Proteostasis Mechanisms of Artemisinin Resistance in P. falciparum Malaria

N. Surolia, Krishanpal Karmodiya, Ananya Ray, 2022, mBio.

Kinetic and structural analysis of the increased affinity of enoyl-ACP (acyl-carrier protein) reductase for triclosan in the presence of NAD+.

M. Kapoor, N. Surolia, A. Surolia, 2004, The Biochemical journal.

Titration calorimetric studies to elucidate the specificity of the interactions of polymyxin B with lipopolysaccharides and lipid A.

N. Surolia, A. Surolia, S. Balasubramanian, 1996, The Biochemical journal.

Discovery of a rhodanine class of compounds as inhibitors of Plasmodium falciparum enoyl-acyl carrier protein reductase.

S. Sharma, G. Kumar, N. Surolia, 2007, Journal of medicinal chemistry.

Green tea catechins potentiate triclosan binding to enoyl-ACP reductase from Plasmodium falciparum (PfENR).

S. Sharma, G. Kumar, N. Surolia, 2007, Journal of medicinal chemistry.

Synthesis and Evaluation of Substituted Pyrazoles: Potential Antimalarials Targeting the Enoyl‐ACP Reductase of Plasmodium Falciparum

M. Kapoor, Sanjay Kumar, G. Kumar, 2006 .

In vitro antimalarial activity of extracts of three plants used in the traditional medicine of India.

N. Surolia, G. P. Bhat, G P Bhat, 2001, The American journal of tropical medicine and hygiene.

Kinetics and Mechanism of the Recognition of Endotoxin by Polymyxin B

N. Surolia, A. Surolia, C. Thomas, 1998 .

Deciphering the key residues in Plasmodium falciparumβ‐ketoacyl acyl carrier protein reductase responsible for interactions with Plasmodium falciparum acyl carrier protein

Rahul Modak, N. Surolia, N. Sahoo, 2008, The FEBS journal.

Isothermal unfolding studies on the apo and holo forms of Plasmodium falciparum acyl carrier protein

Rahul Modak, N. Surolia, Sharmistha Sinha, 2007, The FEBS journal.

Analyses of co‐operative transitions in Plasmodium falciparumβ‐ketoacyl acyl carrier protein reductase upon co‐factor and acyl carrier protein binding

N. Surolia, K. Karmodiya, 2006, The FEBS journal.

Production and purification of refolded recombinant Plasmodium falciparum beta-ketoacyl-ACP reductase from inclusion bodies.

N. Surolia, R. Srivastav, K. Karmodiya, 2005, Protein expression and purification.

Interaction of chloroquine and its analogues with heme: An isothermal titration calorimetric study.

N. Surolia, A. Surolia, C. Thomas, 2000, Biochemical and biophysical research communications.

β‐Ketoacyl‐ACP synthase I/II from Plasmodium falciparum (PfFabB/F)—Is it B or F?

Avadhesha Surolia, N. Surolia, A. Surolia, 2009, IUBMB life.

A unique and differential effect of denaturants on cofactor mediated activation of Plasmodium falciparum β‐ketoacyl‐ACP reductase

N. Surolia, K. Karmodiya, 2007, Proteins.

Insights into the Substrate Specificity of a Thioesterase Rv0098 of Mycobacterium Tuberculosis through X-ray Crystallographic and Molecular Dynamics Studies

N. Surolia, A. Surolia, K. Suguna, 2012, Journal of biomolecular structure & dynamics.

Crystal structure of dimeric FabZ of Plasmodium falciparum reveals conformational switching to active hexamers by peptide flips

S. Sharma, N. Surolia, A. Surolia, 2006, FEBS letters.

Design, synthesis, and application of novel triclosan prodrugs as potential antimalarial and antibacterial agents.

N. Surolia, A. Surolia, P. Parasuraman, 2008, Bioorganic & medicinal chemistry.

Cell surface receptor directed targeting of toxin to human malaria parasite, Plasmodium falciparum

N. Surolia, S. Misquith, 1996, FEBS Letters.

Slow-tight-binding inhibition of enoyl-acyl carrier protein reductase from Plasmodium falciparum by triclosan.

M. Kapoor, N. Surolia, A. Surolia, 2004, The Biochemical journal.

Triclosan as a Systemic Antibacterial Agent in a Mouse Model of Acute Bacterial Challenge

T. Ramya, Shilpi Sharma, N. Surolia, 2003, Antimicrobial Agents and Chemotherapy.

Role of Water in the Specific Binding of Mannose and Mannooligosaccharides to Concanavalin A

Avadhesha Surolia, N. Surolia, A. Surolia, 1998 .

Solution structures of conformationally equilibrium forms of holo-acyl carrier protein (PfACP) from Plasmodium falciparum provides insight into the mechanism of activation of ACPs.

S. Sharma, N. Surolia, A. Surolia, 2006, Biochemistry.

Triclosan: A shot in the arm for antimalarial chemotherapy

N. Surolia, A. Surolia, S. Ramachandra Rao, 2003, Molecular and Cellular Biochemistry.

Basal and starvation-induced autophagy mediates parasite survival during intraerythrocytic stages of Plasmodium falciparum

N. Surolia, Archana Singh, Ravi Manjithaya, 2018, Cell Death Discovery.

Centromere and its associated proteins—what we know about them in Plasmodium falciparum

N. Surolia, G. Verma, 2018, IUBMB life.

Evolutionary significance of self‐acylation property in acyl carrier proteins

N. Surolia, A. Surolia, A. Misra, 2009, IUBMB life.

Synthesis and exploration of novel curcumin analogues as anti-malarial agents.

N. Surolia, A. Surolia, Satyendra Mishra, 2008, Bioorganic & medicinal chemistry.

15-Deoxyspergualin modulates Plasmodium falciparum heat shock protein function.

T. Ramya, N. Surolia, A. Surolia, 2006, Biochemical and biophysical research communications.

The dimerization domain of Pf CENP-C is required for its functions as a centromere protein in human malaria parasite Plasmodium falciparum

N. Surolia, G. Verma, 2014, Malaria Journal.

Plasmodium falciparum CENH3 is able to functionally complement Cse4p and its, C-terminus is essential for centromere function.

N. Surolia, G. Verma, 2013, Molecular and biochemical parasitology.

Crystallization and preliminary crystallographic analysis of beta-hydroxyacyl ACP dehydratase (FabZ) from Plasmodium falciparum.

M. Kapoor, N. Surolia, A. Surolia, 2004, Acta crystallographica. Section D, Biological crystallography.

Enzymic basis of deranged foetal flavin-nucleotide metabolism consequent on immunoneutralization of maternal riboflavin carrier protein in the pregnant rat.

N. Surolia, P. Adiga, K. Krishnamurthy, 1985, The Biochemical journal.

Epigallocatechin gallate is a slow-tight binding inhibitor of enoyl-ACP reductase from Plasmodium falciparum.

S. Sharma, N. Surolia, A. Surolia, 2008, Biochemical and biophysical research communications.

Catalysis and mechanism of malonyl transferase activity in type II fatty acid biosynthesis acyl carrier proteins.

N. Surolia, A. Surolia, A. Misra, 2009, Molecular bioSystems.

Presence of novel triple mutations in the pvdhfr from Plasmodium vivax in Mangaluru city area in the southwestern coastal region of India

N. Surolia, D. Gowda, S. Ghosh, 2018, Malaria Journal.

Kinetic and Thermodynamic Analysis of the Interactions of 23-Residue Peptides with Endotoxin*

Avadhesha Surolia, N. Surolia, A. Surolia, 2001, The Journal of Biological Chemistry.

Mass Spectrometry-Based Systems Approach for Identification of Inhibitors of Plasmodium falciparum Fatty Acid Synthase

Rahul Modak, N. Surolia, A. Surolia, 2007, Antimicrobial Agents and Chemotherapy.

'FAS't inhibition of malaria.

T. Ramya, N. Surolia, A. Surolia, 2004, The Biochemical journal.

Antimycobacterial Activity and Mechanism of Action of NAS-91

N. Surolia, A. Surolia, G. Besra, 2007, Antimicrobial Agents and Chemotherapy.

A novel approach for over-expression, characterization, and isotopic enrichment of a homogeneous species of acyl carrier protein from Plasmodium falciparum.

Rahul Modak, N. Surolia, A. Surolia, 2005, Biochemical and biophysical research communications.

X‐ray crystallographic analysis of the complexes of enoyl acyl carrier protein reductase of Plasmodium falciparum with triclosan variants to elucidate the importance of different functional groups in enzyme inhibition

N. Surolia, A. Surolia, B. Sankaran, 2010, IUBMB life.

Novel diphenyl ethers: design, docking studies, synthesis and inhibition of enoyl ACP reductase of Plasmodium falciparum and Escherichia coli.

T. Ramya, G. Kumar, N. Surolia, 2006, Bioorganic & medicinal chemistry.

N. Surolia, Ravi Manjithaya, Palak Agrawal, 2019, Molecular microbiology.

Presence of novel triple mutations in the pvdhfr from Plasmodium vivax in Mangaluru city area in the southwestern coastal region of India

N. Surolia, D. Gowda, S. Ghosh, 2018, Malaria Journal.

Drug resistance genes: pvcrt-o and pvmdr-1 polymorphism in patients from malaria endemic South Western Coastal Region of India

N. Surolia, D. Gowda, S. Ghosh, 2018, Malaria Journal.

Mutational analysis of the triclosan-binding region of enoyl-ACP (acyl-carrier protein) reductase from Plasmodium falciparum.

M. Kapoor, N. Surolia, A. Surolia, 2004, The Biochemical journal.

Kinetic determinants of the interaction of enoyl-ACP reductase from Plasmodium falciparum with its substrates and inhibitors.

M. Kapoor, N. Surolia, A. Surolia, 2001, Biochemical and biophysical research communications.

Structural basis for triclosan and NAD binding to enoyl-ACP reductase of Plasmodium falciparum.

N. Surolia, A. Surolia, K. Suguna, 2001, Biochemical and biophysical research communications.

Chloroquine inhibits heme-dependent protein synthesis in Plasmodium falciparum.

G. Padmanaban, N. Surolia, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Involvement of Cytochrome P450 in Conferring Chloroquine Resistance to the Malarial Parasite, Plasmodium falciparum

G. Padmanaban, N. Surolia, G. Karthikeyan, 1993 .

Functional characterization of beta-ketoacyl-ACP reductase (FabG) from Plasmodium falciparum.

Aditi Gupta, M. Kapoor, G. Kumar, 2003, Biochemical and biophysical research communications.

Structural basis for the functional and inhibitory mechanisms of β-hydroxyacyl-acyl carrier protein dehydratase (FabZ) of Plasmodium falciparum.

N. Surolia, A. Surolia, K. Suguna, 2011, Journal of structural biology.

Self-acylation properties of type II fatty acid biosynthesis acyl carrier protein.

S. Sharma, N. Surolia, A. Surolia, 2007, Chemistry & biology.

Polyamine synthesis and salvage pathways in the malaria parasite Plasmodium falciparum.

T. Ramya, N. Surolia, A. Surolia, 2006, Biochemical and biophysical research communications.

Apicoplast fatty acid synthesis is essential for pellicle formation at the end of cytokinesis in Toxoplasma gondii

N. Surolia, W. de Souza, R. Vommaro, 2016, Journal of Cell Science.

Apicoplast triose phosphate transporter (TPT) gene knockout is lethal for Plasmodium.

N. Surolia, A. Surolia, Agam P Singh, 2012, Molecular and biochemical parasitology.

Analysis of proteins with the 'hot dog' fold: Prediction of function and identification of catalytic residues of hypothetical proteins

N. Surolia, K. Suguna, Lakshmi S Pidugu, 2009, BMC Structural Biology.

Interactions of Plasmodium falciparum ETRAMP14.1 with PfEMP1, translocon components and other ETRAMP members at the interface of host-parasite

N. Surolia, K. M. V. Sindhe, Ananya Ray, 2019, bioRxiv.

Inhibitors of Nonhousekeeping Functions of the Apicoplast Defy Delayed Death in Plasmodium falciparum

T. Ramya, N. Surolia, A. Surolia, 2006, Antimicrobial Agents and Chemotherapy.

15-Deoxyspergualin Primarily Targets the Trafficking of Apicoplast Proteins in Plasmodium falciparum*

T. Ramya, N. Surolia, A. Surolia, 2007, Journal of Biological Chemistry.

Paradigm shifts in malaria parasite biochemistry and anti-malarial chemotherapy.

N. Surolia, A. Surolia, Satish P RamachandraRao, 2002, BioEssays : news and reviews in molecular, cellular and developmental biology.

SAR and pharmacophore models for the rhodanine inhibitors of Plasmodium falciparum enoyl‐acyl carrier protein reductase

G. Kumar, N. Surolia, A. Surolia, 2010, IUBMB life.

Design, development, synthesis, and docking analysis of 2′‐substituted triclosan analogs as inhibitors for Plasmodium falciparum Enoyl‐ACP reductase

N. Surolia, A. Surolia, N. Kapoor, 2009, IUBMB life.

Triclosan inhibit the growth of the late liver‐stage of Plasmodium

N. Surolia, A. Surolia, Agam P Singh, 2009, IUBMB life.

The ART of Resistance

N. Surolia, Ananya Ray, 2022, Autophagy Reports.

Basal and starvation-induced autophagy mediates parasite survival during intraerythrocytic stages of Plasmodium falciparum

N. Surolia, Archana Singh, Ravi Manjithaya, 2018, Cell Death Discovery.

Structural basis for the variation in triclosan affinity to enoyl reductases.

M. Kapoor, N. Surolia, A. Surolia, 2004, Journal of molecular biology.

Exploring the Interaction Energies for the Binding of Hydroxydiphenyl Ethers to Enoyl-Acyl Carrier Protein Reductases

N. Surolia, A. Surolia, K. Suguna, 2003, Journal of biomolecular structure & dynamics.

Drug resistance genes: pvcrt-o and pvmdr-1 polymorphism in patients from malaria endemic South Western Coastal Region of India

N. Surolia, D. Gowda, S. Ghosh, 2018, Malaria Journal.

The dimerization domain of PfCENP-C is required for its functions as a centromere protein in human malaria parasite Plasmodium falciparum

N. Surolia, G. Verma, 2014, Malaria Journal.

Benzothiophene carboxamide derivatives as novel antimalarials

N. Surolia, A. Surolia, N. Kapoor, 2011, IUBMB life.

Mechanism of foetal wastage following immunoneutralization of riboflavin carrier protein in the pregnant rat: disturbances in flavin coenzyme levels

N. Surolia, P. Adiga, Namita Surolia, 1984, FEBS letters.

Benzothiophene carboxamide derivatives as inhibitors of Plasmodium falciparum enoyl‐ACP reductase

N. Surolia, A. Surolia, N. Kapoor, 2011, IUBMB life.

15‐deoxyspergualin hinders physical interaction between basic residues of transit peptide in PfENR and Hsp70‐1

N. Surolia, A. Surolia, R. R. Singh, 2012, IUBMB life.

Plasmepsin inhibitors: design, synthesis, inhibitory studies and crystal structure analysis.

T. Ramya, N. Surolia, K. Suguna, 2005, The journal of peptide research : official journal of the American Peptide Society.

Is the fatty acid synthesis pathway a good target for anti-malarial therapy?

T. Ramya, N. Surolia, A. Surolia, 2005, IUBMB life.

Triclosan and fatty acid synthesis inPlasmodium falciparum: New weapon for an old enemy

N. Surolia, G. P. Bhat, 2001, Journal of Biosciences.

The many paths to artemisinin resistance in Plasmodium falciparum.

N. Surolia, K. Karmodiya, Kushankur Pandit, 2023, Trends in parasitology.

Apicoplast fatty acid synthesis is essential for pellicle formation at the end of cytokinesis in Toxoplasma gondii

N. Surolia, W. de Souza, R. Vommaro, 2016, Journal of Cell Science.

SAR and pharmacophore models for the rhodanine inhibitors of Plasmodium falciparum enoyl‐acyl carrier protein reductase

G. Kumar, N. Surolia, A. Surolia, 2010, IUBMB life.

Effect of substrate binding loop mutations on the structure, kinetics, and inhibition of enoyl acyl carrier protein reductase from plasmodium falciparum

N. Surolia, A. Surolia, K. Suguna, 2011, IUBMB life.