O. Famin

Inhibition of glutathione-dependent degradation of heme by chloroquine and amodiaquine as a possible basis for their antimalarial mode of action.

H. Ginsburg, M. Krugliak, Jianmin Zhang, 1998, Biochemical pharmacology.

Kinetics of inhibition of glutathione-mediated degradation of ferriprotoporphyrin IX by antimalarial drugs.

H. Ginsburg, M. Krugliak, O. Famin, 1999, Biochemical pharmacology.

Differential effects of 4-aminoquinoline-containing antimalarial drugs on hemoglobin digestion in Plasmodium falciparum-infected erythrocytes.

H. Ginsburg, O. Famin, 2002, Biochemical pharmacology.

The treatment of Plasmodium falciparum-infected erythrocytes with chloroquine leads to accumulation of ferriprotoporphyrin IX bound to particular parasite proteins and to the inhibition of the parasite's 6-phosphogluconate dehydrogenase.

H. Ginsburg, O. Famin, Hagai Ginsburg, 2003, Parasite.