J. Haynes

发表

Discovery of Gene Function by Expression Profiling of the Malaria Parasite Life Cycle

Patricia De la Vega, S. Batalov, Yingyao Zhou, 2003, Science.

Pharmacokinetics of cefixime in the young and elderly.

J. Haynes, R. Faulkner, W. Bohaychuk, 1988, The Journal of antimicrobial chemotherapy.

A proteomic view of the Plasmodium falciparum life cycle

David L. Tabb, Dirk Wolters, John R. Yates, 2002, Nature.

Transcripts of developmentally regulated Plasmodium falciparum genes quantified by real-time RT-PCR.

D. Carucci, P. Blair, A. Witney, 2002, Nucleic acids research.

Identification of Plasmodium knowlesi erythrocyte binding proteins.

J. Haynes, L. Miller, D. Hudson, 1988, Molecular and biochemical parasitology.

Studies on the role of red blood cell glycoproteins as receptors for invasion by Plasmodium falciparum merozoites.

J. Haynes, L. Miller, R. J. Howard, 1982, Molecular and biochemical parasitology.

Protection of Aotus monkeys by Plasmodium falciparum EBA-175 region II DNA prime-protein boost immunization regimen.

S. Hoffman, J. Aguiar, J. K. Moch, 2001, The Journal of infectious diseases.

Monoclonal antibody characterization of the 195-kilodalton major surface glycoprotein of Plasmodium falciparum malaria schizonts and merozoites: identification of additional processed products and a serotype-restricted repetitive epitope.

J. Haynes, C. Haidaris, J. Lyon, 1987, Journal of immunology.

Development and pre-clinical analysis of a Plasmodium falciparum Merozoite Surface Protein-1(42) malaria vaccine.

J. Haynes, Joe D. Cohen, C. Ockenhouse, 2003, Molecular and biochemical parasitology.

Erythrocytic malaria growth or invasion inhibition assays with emphasis on suspension culture GIA.

J. K. Moch, J. Haynes, D. Smoot, 2002, Methods in molecular medicine.

Induction of Biologically Active Antibodies in Mice, Rabbits, and Monkeys by Plasmodium falciparum EBA-175 Region II DNA vaccine

S. Hoffman, J. Aguiar, J. K. Moch, 2001, Molecular medicine.

Receptor-like specificity of a Plasmodium knowlesi malarial protein that binds to Duffy antigen ligands on erythrocytes

J. Dalton, J. Haynes, L. Miller, 1988, The Journal of experimental medicine.

Serum containing tumor necrosis factor is cytotoxic for the human malaria parasite Plasmodium falciparum

J. Haynes, C. Haidaris, M. Meltzer, 1983, Infection and immunity.

Humoral immune responses in volunteers immunized with irradiated Plasmodium falciparum sporozoites.

S. Hoffman, J. Haynes, W. Ballou, 1993, The American journal of tropical medicine and hygiene.

High Antibody Titer against Apical Membrane Antigen-1 Is Required to Protect against Malaria in the Aotus Model

J. Barnwell, J. Haynes, A. Batchelor, 2009, PloS one.

Plasmodium falciparum field isolates use complement receptor 1 (CR1) as a receptor for invasion of erythrocytes.

J. K. Moch, J. Haynes, G. Awandare, 2011, Molecular and biochemical parasitology.

Phase I dose escalation safety and immunogenicity trial of Plasmodium falciparum apical membrane protein (AMA-1) FMP2.1, adjuvanted with AS02A, in malaria-naïve adults at the Walter Reed Army Institute of Research.

V. A. Stewart, J. Haynes, Joe D. Cohen, 2007, Vaccine.

AMalaria Invasion Receptor, the 175-Kilodalton Erythrocyte Binding Antigen ofPlasmodiumfalciparum Recognizes the Terminal Neu5Ac(a2-3)Gal- Sequences ofGlycophorinA

J. Haynes, P. Orlandi, F. Klotz, 2002 .

Binding of Plasmodium falciparum 175-kilodalton erythrocyte binding antigen and invasion of murine erythrocytes requires N-acetylneuraminic acid but not its O-acetylated form

J. Haynes, P. Palese, P. Orlandi, 1992, Molecular and Biochemical Parasitology.

A malaria invasion receptor, the 175-kilodalton erythrocyte binding antigen of Plasmodium falciparum recognizes the terminal Neu5Ac(alpha 2- 3)Gal- sequences of glycophorin A

J. Haynes, P. Orlandi, F. Klotz, 1992, The Journal of cell biology.

Plasmodium falciparum strain-specific human antibody inhibits merozoite invasion of erythrocytes.

J. Haynes, J. Williams, P. Tapchaisri, 1984, The American journal of tropical medicine and hygiene.

Quantitative assessment of antimalarial activity in vitro by a semiautomated microdilution technique

J. Haynes, C. Canfield, J. Chulay, 1979, Antimicrobial Agents and Chemotherapy.

Single‐dose pharmacokinetics of piperacillin and tazobactam in patients with renal disease

J. Haynes, S. Zimmerman, C. Halstenson, 1992, Clinical pharmacology and therapeutics.

Selective stage-specific changes in the permeability to small hydrophilic solutes of human erythrocytes infected with Plasmodium falciparum.

R. Wilson, J. Haynes, J. Chulay, 1985, Molecular and biochemical parasitology.

Profiling invasive Plasmodium falciparum merozoites using an integrated omics approach

J. Rayner, J. K. Moch, J. Haynes, 2017, Scientific Reports.

Localization of the 175-kilodalton erythrocyte binding antigen in micronemes of Plasmodium falciparum merozoites.

J. Haynes, B. Sim, M. Aikawa, 1992, Molecular and biochemical parasitology.

Molecular Factors and Biochemical Pathways Induced by Febrile Temperature in Intraerythrocytic Plasmodium falciparum Parasites

L. Aravind, T. McCutchan, J. K. Moch, 2007, Infection and Immunity.

Localization of the major Plasmodium falciparum glycoprotein on the surface of mature intraerythrocytic trophozoites and schizonts.

J. Barnwell, J. Haynes, L. Miller, 1984, Molecular and biochemical parasitology.

Structure of the gene encoding the immunodominant surface antigen on the sporozoite of the human malaria parasite Plasmodium falciparum.

J. Weber, J. Dame, T. McCutchan, 1984, Science.

Decreased growth of Plasmodium falciparum in red cells containing haemoglobin E, a role for oxidative stress, and a sero-epidemiological correlation.

J. Haynes, C. Diggs, E. Dutoit, 1986, Transactions of the Royal Society of Tropical Medicine and Hygiene.

Two alleles of the 175-kilodalton Plasmodium falciparum erythrocyte binding antigen.

J. Baird, J. Haynes, K. Kain, 1993, Molecular and biochemical parasitology.

Purification, Characterization, and Immunogenicity of the Refolded Ectodomain of the Plasmodium falciparum Apical Membrane Antigen 1 Expressed in Escherichia coli

J. K. Moch, J. Haynes, D. Lanar, 2002, Infection and Immunity.

Binding of Plasmodium merozoite proteins RON2 and AMA1 triggers commitment to invasion

Xavier Ambroggio, J. Kathleen Moch, J. David Haynes, 2011, Proceedings of the National Academy of Sciences.

Primary structure of the 175K Plasmodium falciparum erythrocyte binding antigen and identification of a peptide which elicits antibodies that inhibit malaria merozoite invasion

J. Haynes, P. Orlandi, B. Sim, 1990, The Journal of cell biology.

Characterization of the 175-kilodalton erythrocyte binding antigen of Plasmodium falciparum.

J. Haynes, P. Orlandi, B. Sim, 1990, Molecular and biochemical parasitology.

Evidence for differences in erythrocyte surface receptors for the malarial parasites, Plasmodium falciparum and Plasmodium knowlesi

J. Haynes, F. Mcauliffe, L. Miller, 1977, The Journal of experimental medicine.

Multiple Antigen Peptide Vaccines against Plasmodium falciparum Malaria

Jay A. Berzofsky, J. Kathleen Moch, J. David Haynes, 2010, Infection and Immunity.

Alanine Mutagenesis of the Primary Antigenic Escape Residue Cluster, C1, of Apical Membrane Antigen 1

J. Haynes, A. Batchelor, S. Dutta, 2009, Infection and Immunity.

Recognition of red cells by malaria parasites: the role of erythrocyte-binding proteins.

J. Haynes, L. Miller, T. Hadley, 1991, Transfusion medicine reviews.

Overcoming Antigenic Diversity by Enhancing the Immunogenicity of Conserved Epitopes on the Malaria Vaccine Candidate Apical Membrane Antigen-1

M. Foley, J. K. Moch, J. Haynes, 2013, PLoS pathogens.

Disrupting malaria parasite AMA1 – RON2 interaction with a small molecule prevents erythrocyte invasion

Anton Simeonov, Xin Hu, Ajit Jadhav, 2013, Nature Communications.

Culture of human malaria parasites Plasmodium falciparum

J. Haynes, R. Desjardins, C. Diggs, 1976, Nature.

Automated synchronization of Plasmodium falciparum parasites by culture in a temperature-cycling incubator.

J. K. Moch, J. Haynes, 2002, Methods in molecular medicine.

Absorption kinetics of orally administered leucovorin calcium.

J. Haynes, E. Stokstad, J. Kisicki, 1987, NCI monographs : a publication of the National Cancer Institute.

Pharmacokinetics of Cefixime After Once‐a‐Day and Twice‐a‐Day Dosing to Steady State

J. Haynes, R. Faulkner, W. Bohaychuk, 1987, Journal of clinical pharmacology.

Plasmodium falciparum: further characterization of a functionally active region of the merozoite invasion ligand EBA-175.

J. Haynes, B. Sim, M. Gross, 1994, Experimental parasitology.

Protein disulfide isomerase assisted protein folding in malaria parasites.

J. K. Moch, J. Haynes, H. Nakhasi, 2006, International journal for parasitology.

Falciparum malaria parasites invade erythrocytes that lack glycophorin A and B (MkMk). Strain differences indicate receptor heterogeneity and two pathways for invasion.

J. Haynes, L. Miller, G. Pasvol, 1987, The Journal of clinical investigation.

The pharmacokinetics of cefixime in the fasted and fed state

J. Haynes, R. Faulkner, W. Bohaychuk, 2004, European Journal of Clinical Pharmacology.

Plasmodium falciparum: assessment of in vitro growth by [3H]hypoxanthine incorporation.

J. Haynes, J. Chulay, C. Diggs, 1983, Experimental parasitology.

Epitope map and processing scheme for the 195,000-dalton surface glycoprotein of Plasmodium falciparum merozoites deduced from cloned overlapping segments of the gene.

J. Weber, J. Haynes, J. Lyon, 1986, Proceedings of the National Academy of Sciences of the United States of America.

Plasmodium falciparum: chymotryptic-like proteolysis associated with a 101-kDa acidic-basic repeat antigen.

J. Haynes, P. Orlandi, J. Chulay, 1992, Experimental parasitology.

Plasmodium falciparum antigens synthesized by schizonts and stabilized at the merozoite surface when schizonts mature in the presence of protease inhibitors.

J. Haynes, J. Lyon, 1986, Journal of immunology.

Monoclonal antibody characterization of Plasmodium falciparum antigens in immune complexes formed when schizonts rupture in the presence of immune serum.

C. Atkinson, J. Haynes, J. Lyon, 1987, Journal of immunology.

Plasmodium falciparum antigens synthesized by schizonts and stabilized at the merozoite surface by antibodies when schizonts mature in the presence of growth inhibitory immune serum.

J. Haynes, J. Lyon, J. Chulay, 1986, Journal of immunology.

Inhibitory effects of immune monkey serum on synchronized Plasmodium falciparum cultures.

J. Haynes, J. Chulay, C. Diggs, 1981, The American journal of tropical medicine and hygiene.

Antibodies against the Plasmodium falciparum Receptor Binding Domain of EBA-175 Block Invasion Pathways That Do Not Involve Sialic Acids

S. Hoffman, J. Haynes, B. Sim, 2000, Infection and Immunity.

Production of the Subdomains of the Plasmodium falciparum Apical Membrane Antigen 1 Ectodomain and Analysis of the Immune Response

J. K. Moch, J. Haynes, D. Lanar, 2004, Infection and Immunity.

Mode of Action of Invasion-Inhibitory Antibodies Directed against Apical Membrane Antigen 1 of Plasmodium falciparum

A. Thomas, J. K. Moch, J. Haynes, 2005, Infection and Immunity.

Invasion-inhibitory antibodies inhibit proteolytic processing of apical membrane antigen 1 of Plasmodium falciparum merozoites

J. K. Moch, J. Haynes, D. Lanar, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Inhibition of in vitro growth of Plasmodium falciparum by immune serum from monkeys.

J. Haynes, J. Chulay, C. Diggs, 1981, The Journal of infectious diseases.

Delineation of Stage Specific Expression of Plasmodium falciparum EBA-175 by Biologically Functional Region II Monoclonal Antibodies

S. Hoffman, J. K. Moch, J. Haynes, 2011, PLoS ONE.

Evidence for two-stage binding by the 175-kD erythrocyte binding antigen of Plasmodium falciparum

J. Haynes, K. Kain, P. Orlandi, 1993, The Journal of experimental medicine.

Passive transfer of growth-inhibitory antibodies raised against yeast-expressed recombinant Plasmodium falciparum merozoite surface protein-1(19).

J. K. Moch, J. Haynes, D. Kaslow, 1998, The American journal of tropical medicine and hygiene.

Determinants on surface proteins of Plasmodium knowlesi merozoites common to Plasmodium falciparum schizonts

J. Haynes, R. Carter, D. Wallach, 1980, The Journal of experimental medicine.

Characterization of gp195 processed products purified from Plasmodium falciparum culture supernates.

J. Haynes, J. Lyon, C. Diggs, 1987, Molecular and biochemical parasitology.

Binding of Plasmodium merozoite proteins RON2 and AMA1 triggers commitment to invasion

J. Boothroyd, J. K. Moch, J. Haynes, 2011, Proceedings of the National Academy of Sciences.

Multiple Antigen Peptide Vaccines against Plasmodium falciparum Malaria

J. Berzofsky, J. K. Moch, J. Haynes, 2010, Infection and Immunity.

Alanine Mutagenesis of the Primary Antigenic Escape Residue Cluster, C1, of Apical Membrane Antigen 1

J. Haynes, A. Batchelor, S. Dutta, 2009, Infection and Immunity.