Yan Liu

发表

Structure-activity relationships of C6-uridine derivatives targeting plasmodia orotidine monophosphate decarboxylase.

E. Poduch, A. Bello, E. Pai, 2008, Journal of medicinal chemistry.

Structure-Based Identification of Novel Ligands Targeting Multiple Sites within a Chemokine-G-Protein-Coupled-Receptor Interface.

Yan Liu, Rongshi Li, M Trent Kemp, 2016, Journal of medicinal chemistry.

Discovery and Optimization of Novel, Selective Histone Methyltransferase SET7 Inhibitors by Pharmacophore- and Docking-Based Virtual Screening.

Hualiang Jiang, M. Zheng, Yan Liu, 2015, Journal of medicinal chemistry.

Virtual screening and biological evaluation of novel small molecular inhibitors against protein arginine methyltransferase 1 (PRMT1).

Hualiang Jiang, M. Zheng, Bairong Shen, 2014, Organic & biomolecular chemistry.

Synthesis of Potent Inhibitors of β-Ketoacyl-Acyl Carrier Protein Synthase III as Potential Antimicrobial Agents

Yan Liu, Wu Zhong, Song Li, 2012, Molecules.

Syntheses and studies of hydantoin derivatives as potential anti-tuberculosis inhibitors

Yan Liu, Wu Zhong, Song Li, 2012 .

Cytotoxicity of cantharidin analogues targeting protein phosphatase 2A

Yan Liu, L. Xian, Xu-hui Liu, 2006, Anti-cancer drugs.

Structural Analysis of a Novel Small Molecule Ligand Bound to the CXCL12 Chemokine

Yan Liu, B. Volkman, Emmanuel W Smith, 2014, Journal of medicinal chemistry.

Fragment-based optimization of small molecule CXCL12 inhibitors for antagonizing the CXCL12/CXCR4 interaction.

Yan Liu, B. Volkman, Emmanuel W Smith, 2013, Current topics in medicinal chemistry.

Anti-tumour effects of xanthone derivatives and the possible mechanisms of action

Yan Liu, L. Xian, Yue-li Sun, 2011, Investigational New Drugs.

Discovery of nonsteroidal glucocorticoid receptor ligands based on 6-indole-1,2,3,4-tetrahydroquinolines.

Yan Liu, Steven L. Roach, J. Miner, 2008, Bioorganic & medicinal chemistry letters.

Design, Synthesis, and Biological Evaluation of Novel Covalent Inhibitors Targeting Focal Adhesion Kinase.

Yan Liu, Ming-hai Tang, Lijuan Chen, 2021, Bioorganic & medicinal chemistry letters.

Synthesis and pharmacological activities of xanthone derivatives as alpha-glucosidase inhibitors.

Yan Liu, Wen-Hua Chen, Bo-Chi Wang, 2006, Bioorganic & medicinal chemistry.

Binding mechanism and synergetic effects of xanthone derivatives as noncompetitive α-glucosidase inhibitors: a theoretical and experimental study.

Yan Liu, Hwangseo Park, Zhuofeng Ke, 2013, The journal of physical chemistry. B.

Synthesis, inhibitory activities, and QSAR study of xanthone derivatives as alpha-glucosidase inhibitors.

Yan Liu, Jianfang Cui, Zhuofeng Ke, 2008, Bioorganic & medicinal chemistry.

Synthesis of xanthone derivatives with extended π-systems as α-glucosidase inhibitors: Insight into the probable binding mode

Lin Ma, Yan Liu, Wen-Hua Chen, 2007 .

Synthesis and Binding Properties of a New Fluorescent Molecular Sensor Based on a Triazole Nucleoside

Yan Liu, Lijuan Guo, Dehua Zhang, 2016 .

Potent Antitumor Activities and Structure Basis of the Chiral β-Lactam Bridged Analogue of Combretastatin A-4 Binding to Tubulin.

Hualiang Jiang, Yan Liu, Pengfei Zhou, 2016, Journal of medicinal chemistry.

Development and Validation of a Phenotypic High-Content Imaging Assay for Assessing the Antiviral Activity of Small-Molecule Inhibitors Targeting Zika Virus

Yan Liu, Rongshi Li, J. Bernatchez, 2018, Antimicrobial Agents and Chemotherapy.

Novel interactions of fluorinated nucleotide derivatives targeting orotidine 5'-monophosphate decarboxylase.

M. E. Meza-Aviña, E. Poduch, E. Pai, 2011, Journal of medicinal chemistry.

Structural determinants for the inhibitory ligands of orotidine-5'-monophosphate decarboxylase.

M. E. Meza-Aviña, E. Poduch, E. Pai, 2010, Bioorganic & medicinal chemistry.

Discovery of Marinopyrrole A (Maritoclax) as a Selective Mcl-1 Antagonist that Overcomes ABT-737 Resistance by Binding to and Targeting Mcl-1 for Proteasomal Degradation*

Yan Liu, Shen-Shu Sung, Rongshi Li, 2012, The Journal of Biological Chemistry.

Structure-activity relationships of orotidine-5'-monophosphate decarboxylase inhibitors as anticancer agents.

Yan Liu, Lakshmi P Kotra, E. Poduch, 2009, Journal of medicinal chemistry.

Marinopyrrole Derivatives as Potential Antibiotic Agents against Methicillin-Resistant Staphylococcus aureus (III)

V. Nizet, M. Hensler, Yan Liu, 2014, Marine drugs.

Marinopyrrole Derivatives as Potential Antibiotic Agents against Methicillin-Resistant Staphylococcus aureus (I)

V. Nizet, M. Hensler, Yan Liu, 2012, Marine drugs.

Marinopyrrole Derivatives with Sulfide Spacers as Selective Disruptors of Mcl-1 Binding to Pro-Apoptotic Protein Bim

Yan Liu, K. Nicolaou, N. Simmons, 2014, Marine drugs.

Structure-based design and SAR development of 5,6-dihydroimidazolo[1,5-f]pteridine derivatives as novel Polo-like kinase-1 inhibitors.

Yan Liu, Jeffrey Stafford, David Hosfield, 2017, Bioorganic & medicinal chemistry letters.

Pyrazolo[1,5-a]pyrimidine Based Trk Inhibitors: Design, Synthesis, Biological Activity Evaluation.

Yan Liu, W. Fan, Chunlei Tang, 2020, Bioorganic & medicinal chemistry letters.

Fragment-based and structure-guided discovery and optimization of Rho kinase inhibitors.

W. Guida, Yan Liu, S. Sebti, 2012, Journal of medicinal chemistry.

Cyclic Marinopyrrole Derivatives as Disruptors of Mcl-1 and Bcl-xL Binding to Bim

Yan Liu, K. Nicolaou, N. Simmons, 2014, Marine drugs.

Identification of novel ROCK inhibitors with anti-migratory and anti-invasive activities

Yan Liu, S. Sebti, Rongshi Li, 2013, Oncogene.

Novel fluorinated pyrrolomycins as potent anti-staphylococcal biofilm agents: Design, synthesis, pharmacokinetics and antibacterial activities.

Yan Liu, Jialin C. Zheng, Zhen Qiao, 2016, European journal of medicinal chemistry.

Effects of novel pyrrolomycin MP1 in MYCN amplified chemoresistant neuroblastoma cell lines alone and combined with temsirolimus

Yan Liu, Zhen Qiao, Rongshi Li, 2019, BMC Cancer.

Development and validation of a phenotypic high-content imaging assay for assessing the antiviral activity of small-molecule inhibitors targeting the Zika virus

Yan Liu, Rongshi Li, J. Bernatchez, 2018, bioRxiv.

Design, synthesis and evaluation of marinopyrrole derivatives as selective inhibitors of Mcl-1 binding to pro-apoptotic Bim and dual Mcl-1/Bcl-xL inhibitors.

Yan Liu, Rongshi Li, Jerry Li, 2015, European journal of medicinal chemistry.

Effects of novel pyrrolomycin MP1 in MYCN amplified chemoresistant neuroblastoma cell lines alone and combined with temsirolimus

Yan Liu, Yan Liu, Zhen Qiao, 2019, BMC Cancer.

Development and Validation of a Phenotypic High-Content Imaging Assay for Assessing the Antiviral Activity of Small-Molecule Inhibitors Targeting Zika Virus

Yan Liu, Rongshi Li, J. Siqueira-Neto, 2018, Antimicrobial Agents and Chemotherapy.