A. Matsuda

发表

New neplanocin analogues. 12. Alternative synthesis and antimalarial effect of (6'R)-6'-C-methylneplanocin A, a potent AdoHcy hydrolase inhibitor.

S. Shuto, N. Minakawa, S. Niizuma, 2002, Journal of medicinal chemistry.

Irradiation Induces the Proapoptotic State Independent of the Loss of Clonogenic Ability in Chinese Hamster V 79 Cells

A. Matsuda, O. Inanami, M. Kuwabara, 2017 .

X Irradiation Induces the Proapoptotic State Independent of the Loss of Clonogenic Ability in Chinese Hamster V79 Cells

A. Matsuda, O. Inanami, M. Kuwabara, 2005, Radiation research.

No enhancement of nuclear entry by direct conjugation of a nuclear localization signal peptide to linearized DNA.

N. Minakawa, A. Matsuda, H. Harashima, 2003, Bioconjugate chemistry.

Association between IFNA genotype and the risk of sarcoidosis

J. Casanova, A. Matsuda, S. Ohno, 2004, Human Genetics.

Antibacterial Nucleoside Natural Products Inhibiting Phospho-MurNAc-Pentapeptide Translocase; Chemistry and Structure-Activity Relationship.

A. Matsuda, M. Yamaguchi, S. Ichikawa, 2015, Current medicinal chemistry.

Total synthesis of caprazol, a core structure of the caprazamycin antituberculosis antibiotics.

A. Matsuda, S. Ichikawa, S. Hirano, 2005, Angewandte Chemie.

SYNTHESIS OF COMPLEX NUCLEOSIDE ANTIBIOTICS

A. Matsuda, S. Ichikawa, 2005, Nucleosides, nucleotides & nucleic acids.

Total synthesis of (+)-FR-900493 and establishment of its absolute stereochemistry

A. Matsuda, S. Ichikawa, S. Hirano, 2007 .

Development of a highly beta-selective ribosylation reaction without using neighboring group participation: total synthesis of (+)-caprazol, a core structure of caprazamycins.

A. Matsuda, S. Ichikawa, S. Hirano, 2007, The Journal of organic chemistry.

Synthesis of caprazamycin analogues and their structure--activity relationship for antibacterial activity.

A. Matsuda, S. Ichikawa, S. Hirano, 2008, The Journal of organic chemistry.

Structure-activity relationship of truncated analogs of caprazamycins as potential anti-tuberculosis agents.

A. Matsuda, S. Ichikawa, S. Hirano, 2008, Bioorganic & medicinal chemistry.

Design and synthesis of diketopiperazine and acyclic analogs related to the caprazamycins and liposidomycins as potential antibacterial agents.

A. Matsuda, S. Ichikawa, S. Hirano, 2008, Bioorganic & medicinal chemistry.

Synthetic study of muraymycins using Ugi-four component reaction.

A. Matsuda, S. Ichikawa, S. Hirano, 2008, Nucleic acids symposium series.

Total synthesis of (-)-muraymycin D2 and its epimer.

A. Matsuda, S. Ichikawa, Tetsuya Tanino, 2010, The Journal of organic chemistry.

Synthesis and Biological Evaluation of Muraymycin Analogues Active against Anti-Drug-Resistant Bacteria.

A. Matsuda, A. Bouhss, S. Ichikawa, 2010, ACS medicinal chemistry letters.

Three-dimensional structure-activity relationship study of belactosin A and its stereo- and regioisomers: development of potent proteasome inhibitors by a stereochemical diversity-oriented strategy.

S. Shuto, A. Matsuda, H. Yokosawa, 2009, Organic & biomolecular chemistry.

Use of Cotton Rats to Evaluate the Efficacy of Antivirals in Treatment of Measles Virus Infections

E. De Clercq, N. Minakawa, A. Matsuda, 2000, Antimicrobial Agents and Chemotherapy.

Efficient synthesis of Hsp90 inhibitor dimers as potential antitumor agents.

A. Matsuda, S. Ichikawa, Hironori Sekiguchi, 2010, Bioorganic & medicinal chemistry.

Design and synthesis of 3′,5′-ansa-adenosines as potential Hsp90 inhibitors

A. Matsuda, S. Ichikawa, K. Muranaka, 2009 .

Synthesis of Hsp90 inhibitor dimers as potential antitumor agents.

A. Matsuda, S. Ichikawa, K. Muranaka, 2008, Bioorganic & medicinal chemistry.

Synthesis of 2‐Amino‐4‐Fluoropyridine‐C‐Nucleoside Phosphoramidite for Incorporation into Oligonucleotides

A. Matsuda, Kousuke Sato, 2019, Current protocols in nucleic acid chemistry.

Mechanism‐Based Inhibitor of DNA Cytosine‐5 Methyltransferase by a SNAr Reaction with an Oligodeoxyribonucleotide Containing a 2‐Amino‐4‐Halopyridine‐C‐Nucleoside

A. Matsuda, I. Suetake, S. Tajima, 2018, Chembiochem : a European journal of chemical biology.

Total synthesis and biological evaluation of pacidamycin D and its 3'-hydroxy analogue.

A. Matsuda, M. Sakagami, F. Feng, 2012, The Journal of organic chemistry.

Total synthesis of pacidamycin D by Cu(I)-catalyzed oxy enamide formation.

A. Matsuda, M. Sakagami, F. Feng, 2011, Organic letters.

Lipid raft disruption prevents apoptosis induced by 2-chloro-2'-deoxyadenosine (Cladribine) in leukemia cell lines.

A. Matsuda, O. Inanami, M. Kuwabara, 2006, Leukemia research.

Homologous recombination as a resistance mechanism to replication-induced double-strand breaks caused by the antileukemia agent CNDAC.

A. Matsuda, Z. Estrov, H. Kantarjian, 2010, Blood.

A Nucleoside Anticancer Drug, 1-(3-C-Ethynyl-β-D-Ribo-Pentofuranosyl)Cytosine, Induces Depth-Dependent Enhancement of Tumor Cell Death in Spread-Out Bragg Peak (SOBP) of Proton Beam

A. Matsuda, H. Shirato, S. Takao, 2016, PloS one.

Identification of A-minor tertiary interactions within a bacterial group I intron active site by 3-deazaadenosine interference mapping.

S. Strobel, N. Minakawa, A. Matsuda, 2002, Biochemistry.

PK-PD modeling of 1-(3-C-ethynyl-beta-D-ribo-pentofuranosyl)cytosine and the enhanced antitumor effect of its phospholipid derivatives in long-circulating liposomes.

S. Shuto, A. Matsuda, H. Harashima, 2009, International journal of pharmaceutics.

Four-Hydrogen-Bonding Base Pairs in Oligonucleotides: Design, Synthesis, and Properties

N. Minakawa, A. Matsuda, Noriko Saito-Tarashima, 2018 .

Transcription of 4'-thioDNA templates to natural RNA in vitro and in mammalian cells.

N. Minakawa, A. Matsuda, H. Kamiya, 2015, Chemical communications.

Nucleosides and nucleotides. 135. DNA duplex and triplex formation and resistance to nucleolytic degradation of oligodeoxynucleotides containing syn-norspermidine at the 5-position of 2'-deoxyuridine.

A. Matsuda, A. Ono, H. Nara, 1995, Bioconjugate chemistry.

Total synthesis of quinaldopeptin and its analogues.

A. Matsuda, S. Ichikawa, T. Okamura, 2013, The Journal of organic chemistry.

Nucleosides and nucleotides. 120. Stereoselective radical deoxygenation of tert-alcohols in the sugar moiety of nucleosides: synthesis of 2′,3′-dideoxy-2′-C-methyl- -2′-C-ethynyl-β-d-threo-pentofuranosyl pyrimidines and adenine as potential antiviral and antitumor agents☆

A. Matsuda, Takuma Sasaki, A. Kakefuda, 1993 .

Determination of the Group Electronegativity of CF3 Group in 3′-O-CF3-Thymidine by 1-NMR

A. Matsuda, J. Chattopadhyaya, C. Thibaudeau, 1999 .

Design, Synthesis, and Biological Activity of Isosyringolin A.

A. Matsuda, S. Iida, S. Ichikawa, 2016, Organic letters.

Transient Expression of Drosophila melanogaster Deoxynucleoside Kinase Gene Enhances Cytotoxicity of Nucleoside Analogs

A. Matsuda, H. Ochiai, H. Harashima, 2006, Nucleosides, nucleotides & nucleic acids.

Design, synthesis and biological evaluation of 5'-C-piperidinyl-5'-O-aminoribosyluridines as potential antibacterial agents.

A. Matsuda, S. Ichikawa, Takeshi Nakaya, 2015, Organic & biomolecular chemistry.

Synthesis of isoxazolidine-containing uridine derivatives as caprazamycin analogues.

A. Matsuda, S. Ichikawa, M. Yamaguchi, 2015, Organic & biomolecular chemistry.

Carbacaprazamycins: Chemically Stable Analogues of the Caprazamycin Nucleoside Antibiotics.

A. Matsuda, S. Ichikawa, M. Yamaguchi, 2015, ACS infectious diseases.

Construction of a cis-cyclopropane via reductive radical decarboxylation. Enantioselective synthesis of cis- and trans-1-arylpiperazyl-2-phenylcyclopropanes designed as antidopaminergic agents.

S. Shuto, A. Matsuda, H. Abe, 2003, The Journal of organic chemistry.

S. Shuto, N. Minakawa, A. Matsuda, 2018, Antiviral research.

The Escherichia coli alkA Gene Is Activated to Alleviate Mutagenesis by an Oxidized Deoxynucleoside

P. Ruoff, A. Matsuda, I. Leiros, 2020, Frontiers in Microbiology.

Nucleosides and nucleotides. 103. 2-Alkynyladenosines: a novel class of selective adenosine A2 receptor agonists with potent antihypertensive effects.

A. Matsuda, H. Homma, Y. Watanabe, 1992, Journal of medicinal chemistry.

Chemistry, Properties, and in Vitro and in Vivo Applications of 2′‐O‐Methoxyethyl‐4′‐thioRNA, a Novel Hybrid Type of Chemically Modified RNA

N. Minakawa, A. Matsuda, N. Yamazaki, 2014, Chembiochem : a European journal of chemical biology.

Synthesis of All Stereoisomers of Monomeric Spectomycin A1/A2 and Evaluation of Their Protein SUMOylation-Inhibitory Activity.

A. Matsuda, Daisuke Sekine, M. Sodeoka, 2019, Chemistry.

2'-C-cyano-2'-deoxy-1-beta-D-arabino-pentofuranosylcytosine: a novel anticancer nucleoside analog that causes both DNA strand breaks and G(2) arrest.

A. Matsuda, W. Plunkett, P. Huang, 2001, Molecular pharmacology.

An oligodeoxyribonucleotide containing 5-formyl-2'-deoxycytidine (fC) at the CpG site forms a covalent complex with DNA cytosine-5 methyltransferases (DNMTs).

A. Matsuda, S. Ichikawa, Kousuke Sato, 2016, Bioorganic & medicinal chemistry letters.

Synthesis and physical and physiological properties of 4'-thioRNA: application to post-modification of RNA aptamer toward NF-κB

N. Minakawa, A. Matsuda, S. Hoshika, 2019 .

Synthesis and physical and physiological properties of 4 0-thioRNA : application to post-modification of RNA aptamer toward NFk B

N. Minakawa, A. Matsuda, S. Hoshika, 2019 .

Synthesis and physical and physiological properties of 4'-thioRNA: application to post-modification of RNA aptamer toward NF-kappaB.

N. Minakawa, A. Matsuda, S. Hoshika, 2004, Nucleic acids research.

Antisense oligodeoxynucleotides: useful tool for search and assessment of new targets for anti-malarial drugs.

S. Shuto, Y. Wataya, A. Matsuda, 1999, Nucleic acids symposium series.

pentofuranosyl)cytosine (ECyd, TAS-106) against an established gemcitabine (dFdCyd)-resistant human pancreatic cancer cell line

A. Fujioka, M. Fukushima, A. Matsuda, 2005 .

Possible antitumor activity of 1‐(3‐C‐ethynyl‐β‐d‐ribo‐pentofuranosyl)cytosine (ECyd, TAS‐106) against an established gemcitabine (dFdCyd)‐resistant human pancreatic cancer cell line

A. Fujioka, M. Fukushima, A. Matsuda, 2005, Cancer science.

Synthesis of the cyclic and acyclic acetal derivatives of 1-(3-C-ethynyl-beta-D-ribo-pentofuranosyl)cytosine, a potent antitumor nucleoside. Design of prodrugs to be selectively activated in tumor tissues via the bio-reduction-hydrolysis mechanism.

S. Shuto, A. Matsuda, M. Nomura, 2003, Bioorganic & medicinal chemistry.

Antibody-mediated molecular-targeted therapy for adult T-cell leukemia: Recent progress and future challenges in the treatment of cancers

A. Matsuda, N. Maeda, K. Maenaka, 2016 .

RNA Bioisosteres: Chemistry and Properties of 4′-thioRNA and 4′-selenoRNA

N. Minakawa, A. Matsuda, Noriko Saito-Tarashima, 2018 .

Synthesis and properties of 4′-ThioDNA: unexpected RNA-like behavior of 4′-ThioDNA

N. Minakawa, A. Matsuda, Naonori Inoue, 2006, Nucleic acids research.

Nucleosides and nucleotides. 171. Thermal and nuclease stabilities of G-quadruplexes consisting of oligodeoxynucleotides containing 5-[N-[2-[N,N-bis(2-amino-ethyl)amino]ethyl]carbamoyl]-2′-deoxyuridine or 5-[N-[3-[N,N-bis(3-aminopropyl)amino]propyl]carbamoyl]-2′-deoxyuridine

A. Matsuda, Y. Ueno, M. Mikawa, 1997 .

Ataxia-telangiectasia and Rad3-related and DNA-dependent protein kinase cooperate in G2 checkpoint activation by the DNA strand-breaking nucleoside analogue 2′-C-cyano-2′-deoxy-1-β-d-arabino-pentofuranosylcytosine

A. Matsuda, Xiaojun Liu, W. Plunkett, 2008, Molecular Cancer Therapeutics.

Nucleosides and nucleotides. 189. Investigation of the stereoselective coupling of thymine with meso-thiolane-3,4-diol-1-oxide derivatives via the Pummerer reaction

N. Minakawa, A. Matsuda, T. Naka, 1999 .

Fluorescence Properties of 5‐(5,6‐Dimethoxybenzothiazol‐2‐yl)‐2′‐deoxyuridine (dbtU) and Oligodeoxyribonucleotides Containing dbtU

A. Matsuda, Kousuke Sato, W. Hirose, 2011 .

Synthesis of 1,8-naphthyridine C-nucleosides and their base-pairing properties in oligodeoxynucleotides: thermally stable naphthyridine:imidazopyridopyrimidine base-pairing motifs.

N. Minakawa, A. Matsuda, Sadao Hikishima, 2005, Angewandte Chemie.

Synthesis of 5''-branched derivatives of cyclic ADP-carbocyclic-ribose, a potent Ca2+-mobilizing agent: The first antagonists modified at the N1-ribose moiety.

S. Shuto, A. Matsuda, T. Murayama, 2008, Bioorganic & medicinal chemistry letters.

Imbalance of deoxyribonucleoside triphosphates, DNA double-strand breaks, and cell death caused by 2-chlorodeoxyadenosine in mouse FM3A cells.

Y. Wataya, A. Matsuda, K. Watanabe, 1989, Cancer research.

The mechanism of 2-chlorodeoxyadenosine-induced cell death.

Y. Wataya, A. Matsuda, J. Minowada, 1989, Advances in experimental medicine and biology.

Recognition of nucleotide analogs containing the 7,8-dihydro-8-oxo structure by the human MTH1 protein.

N. Minakawa, A. Matsuda, S. Pochet, 2006, Journal of biochemistry.

Synthesis and crystal structure of 2′-deoxy-2′-fluoro-4′-thioribonucleosides: substrates for the synthesis of novel modified RNAs

N. Minakawa, A. Matsuda, M. Shiro, 2008 .

Synthesis of 3′-β-carbamoylmethylcytidine (CAMC) and its derivatives as potential antitumor agents

S. Shuto, N. Minakawa, A. Matsuda, 2006 .

A highly stereoselective samarium diiodide-promoted aldol reaction with 1'-phenylseleno-2'-keto nucleosides. Synthesis of 1'alpha-branched uridine derivatives.

S. Shuto, A. Matsuda, S. Ichikawa, 2002, The Journal of organic chemistry.

Antitumor activity of sugar‐modified cytosine nucleosides

A. Matsuda, Takuma Sasaki, 2004, Cancer science.

5-Hydroxymethyltubercidin exhibits potent antiviral activity against flaviviruses and coronaviruses, including SARS-CoV-2

N. Minakawa, A. Matsuda, Y. Orba, 2021, iScience.

A novel lysine-substituted nucleoside in the first position of the anticodon of minor isoleucine tRNA from Escherichia coli

A. Matsuda, S. Yokoyama, Y. Kuchino, 1989, The Journal of biological chemistry.

Synthesis and biological evaluation of quinaldopeptin.

A. Matsuda, S. Ichikawa, M. Shiro, 2014, The Journal of organic chemistry.

The bisected s-trans conformation-controlled highly stereoselective addition of Grignard reagents to C-cyclopropylaldonitrone. An efficient synthesis of 1-phenyl-2-[(S)-1-aminoalkyl]-N,N-diethylcyclopropanecarboxamides, a new class of potent NMDA receptor antagonists

S. Shuto, A. Matsuda, H. Abe, 2001 .

Synthesis of linked triple helical DNAs possessing high affinity to triple helical DNA binding protein.

Y. Kitade, M. Nakanishi, A. Matsuda, 2006, Bioorganic & medicinal chemistry letters.

Thermal stability of triple helical DNAs containing 2'-deoxyinosine and 2'-deoxyxanthosine.

Y. Kitade, A. Matsuda, Aya Shibata, 2004, Bioorganic & medicinal chemistry.

Effects of 5-(N-aminohexyl)carbamoyl-2'-deoxyuridine on endonuclease stability and the ability of oligodeoxynucleotide to activate RNase H.

A. Matsuda, I. Kumagai, N. Haginoya, 1997, Nucleic acids research.

Design, Synthesis and Biological Evaluation of a Structurally Simplified Syringolin A Analogues.

A. Matsuda, S. Ichikawa, S. Kitahata, 2016, Chemical & pharmaceutical bulletin.

Natural Product Synthesis by Multicomponent Reaction and Structure-activity Relationship Study

A. Matsuda, S. Ichikawa, Takuya Chiba, 2016 .

Structure-activity relationship study of syringolin A as a potential anticancer agent.

A. Matsuda, S. Ichikawa, Takuya Chiba, 2015, Bioorganic & medicinal chemistry letters.

Total synthesis of syringolin A and improvement of its biological activity.

A. Matsuda, M. Asaka, S. Ichikawa, 2014, Angewandte Chemie.

Synthesis, thermal stability and resistance to enzymatic hydrolysis of the oligonucleotides containing 5-(N-aminohexyl)carbamoyl-2'-O-methyluridines.

Y. Komatsu, A. Matsuda, Y. Ueno, 2003, Nucleic acids research.

Nucleosides and nucleotides. Part 214: thermal stability of triplexes containing 4'alpha-C-aminoalkyl-2'-deoxynucleosides.

S. Shuto, A. Matsuda, Y. Ueno, 2002, Bioorganic & medicinal chemistry.

Anti-parasite activity of nucleoside analogues in Leishmania tropica promastigotes.

Y. Wataya, A. Matsuda, M. Saneyoshi, 1984, Nucleic acids symposium series.

Synthesis of 8, 6'-Cyclo-6'-deoxyhexofuranosyladenines : Adenosines Fixed in an Anti-conformation (Nucleosides and Nucleotides. LXVI)

A. Matsuda, T. Ueda, 1986 .

Nucleosides. 123. Synthesis of antiviral nucleosides: 5-substituted 1-(2-deoxy-2-halogeno-beta-D-arabinofuranosyl)cytosines and -uracils. Some structure-activity relationships.

A. Matsuda, M. Chun, C. K. Chu, 1983, Journal of medicinal chemistry.

Nucleosides and Nucleotides. 139. Stereoselective Synthesis of (2′S)-2′-C-Alkyl-2′-deoxyuridines # 1

S. Shuto, A. Matsuda, T. Iino, 1996 .

Nucleosides and nucleotides. 128. (2′S)-2′-deoxy-2′-C-methyl-5-iodouridine (SMIU) as a novel potent anti-herpes virus agent☆

S. Shuto, A. Matsuda, M. Baba, 1994 .

Repair of 2'-C-cyano-2'-deoxy-1-beta-D-arabino-pentofuranosylcytosine-induced DNA single-strand breaks by transcription-coupled nucleotide excision repair.

A. Matsuda, Xiaojun Liu, W. Plunkett, 2008, Cancer research.

2-Chloro-2′-deoxyadenosine induces apoptosis through the Fas/Fas ligand pathway in human leukemia cell line MOLT-4

A. Matsuda, K. Takahashi, O. Inanami, 2000, Leukemia.

Inactivation of inosine 5'-monophosphate dehydrogenase by the antiviral agent 5-ethynyl-1-beta-D-ribofuranosylimidazole-4-carboxamide 5'-monophosphate.

K. Biemann, N. Minakawa, A. Matsuda, 1996, Biochemistry.

Mammalian 5-formyluracil-DNA glycosylase. 2. Role of SMUG1 uracil-DNA glycosylase in repair of 5-formyluracil and other oxidized and deaminated base lesions.

A. Matsuda, H. Ide, A. Masaoka, 2003, Biochemistry.

Antitumor Effect of Sugar-Modified Cytosine Nucleosides on Growth of Adult T-Cell Leukemia Cells in Mice

A. Matsuda, N. Maeda, Masahiko Takahashi, 2020, Vaccines.

Anti-herpes Activities of Isonucleoside Analogues with Variable Bases at the 2′ Position

S. Shuto, A. Matsuda, M. Baba, 1995 .

Structural feature of bent DNA recognized by HMGB1.

A. Matsuda, Kyoko Furuita, C. Kojima, 2011, Journal of the American Chemical Society.

Synthesis of 4,8-anhydro-D-glycero-D-ido-nonanitol 1,6,7-trisphosphate as a novel IP3 receptor ligand using a stereoselective radical cyclization reaction based on a conformational restriction strategy

Colin W. Taylor, S. Shuto, A. Matsuda, 2005 .

Crystallization and preliminary X-ray analysis of human uridine-cytidine kinase 2.

M. Fukushima, A. Matsuda, F. Inagaki, 2003, Acta crystallographica. Section D, Biological crystallography.

Mechanism of action of a new antitumor ribonucleoside, 1-(3-C-ethynyl-beta-D-ribo-pentofuranosyl)cytosine (ECyd, TAS-106), differs from that of 5-fluorouracil.

M. Fukushima, A. Matsuda, Takuma Sasaki, 2007, Oncology reports.

Cellular pharmacokinetics and pharmacodynamics of the deoxycytidine analog 2'-C-cyano-2'-deoxy-1-beta-D-arabino-pentofuranosylcytosine (CNDAC).

A. Matsuda, W. Plunkett, P. Huang, 2001, Biochemical pharmacology.

Extraction of Proteins Based on Phase Separation in Aqueous Triblock Copolymer Surfactant Solutions.

A. Matsuda, H. Tani, T. Kamidate, 1997 .

Synthesis of 1′-fluorouracil nucleosides as potential antimetabolites

S. Shuto, A. Matsuda, T. Kodama, 2006 .

Synthesis of pyrimidine 1′-fluoronucleosides☆

S. Shuto, A. Matsuda, T. Kodama, 2006 .

Synthesis and properties of 2'-deoxy-8,2'-methylene-cycloadenosine

A. Matsuda, T. Miyasaka, Hiromichi Tanaka, 1985 .

Divergent synthesis of kinase inhibitor derivatives, leading to discovery of selective Gck inhibitors.

S. Shuto, A. Matsuda, T. Nomura, 2017, Bioorganic & medicinal chemistry letters.

A versatile modification of on-column oligodeoxynucleotides using a copper-catalyzed oxidative acetylenic coupling reaction.

N. Minakawa, A. Matsuda, Y. Ono, 2003, Journal of the American Chemical Society.

[Development of highly nuclease-resistant chemically-modified oligonucleotides].

A. Matsuda, 2011, Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan.

NMR conformation of (-)-beta-D-aristeromycin and its 2 '-deoxy and 3 '-deoxy counterparts in aqueous solution

A. Matsuda, V. Marquez, J. Chattopadhyaya, 1998 .

Crystallographic studies on damaged DNAs IV. N( 4)-methoxycytosine shows a second face for Watson-Crick base-pairing, leading to purine transition mutagenesis.

A. Matsuda, T. Hikima, M. Tsunoda, 2001, Nucleic acids research.

Highly Nuclease-Resistant Phosphodiester-Type Oligodeoxynucleotides Containing 4‘α-C-Aminoalkylthymidines Form Thermally Stable Duplexes with DNA and RNA. A Candidate for Potent Antisense Molecules†

A. Matsuda, Y. Ueno, M. Kanazaki, 2000 .

A new synthesis of 5'-deoxy-8,5'-cyclo-adenosine and -inosine: conformationally-fixed purine nucleosides (nucleosides and nucleotides. XVI).

A. Matsuda, K. Muneyama, T. Ueda, 1976, Nucleic acids research.

Synthesis and physical and physiological properties of 4 0 -thioRNA: application to post-modification of RNA aptamer toward NF- k B

N. Minakawa, A. Matsuda, S. Hoshika, 2004 .

Deletion Mutants of Human Deoxycytidine Kinase mRNA in Cells Resistant to Antitumor Cytosine Nucleosides

A. Matsuda, Takuma Sasaki, Y. Endo, 2001, Japanese journal of cancer research : Gann.

Treatment combining X-irradiation and a ribonucleoside anticancer drug, TAS106, effectively suppresses the growth of tumor cells transplanted in mice.

A. Matsuda, O. Inanami, M. Kuwabara, 2007, International journal of radiation oncology, biology, physics.

Amyloid beta cleavage by ANA‐TA9, a synthetic peptide from the ANA/BTG3 Box A region

M. Saito, A. Matsuda, T. Sakane, 2021, Alzheimer's & dementia.

Incorporation of 2′‐Deoxy‐2′‐isonucleoside 5′‐Triphosphates (iNTPs) into DNA by A‐ and B‐Family DNA Polymerases with Different Recognition Mechanisms

A. Matsuda, Kousuke Sato, Takaaki Ogino, 2010, Chembiochem : a European journal of chemical biology.

Enzymatic and chemical synthesis of isodeoxynucleic acid (INA) and its properties.

A. Matsuda, Kousuke Sato, Naonori Inoue, 2007, Nucleic acids symposium series.

Structural insights into inhibition of Lipid I production in bacterial cell wall synthesis

A. Matsuda, Seok-Yong Lee, Jiyong Hong, 2016, Nature.

A lithiation route to C-5 substitution of an imidazole nucleoside and its application to the synthesis of 3-deazaguanosine

A. Matsuda, Masahiro Suzuki, T. Miyasaka, 1986 .

Nucleosides and nucleotides. 147. Synthesis of DNA dodecamers containing oxetanocin A and (2R, 3R)-2-C-(adenin-9-yl)-1,4-anhydro-2,3-dideoxy-3-C-hydroxymethyl-D-arabitol☆

A. Matsuda, A. Ono, A. Kakefuda, 1996 .

Nucleosides and Nucleotides. 104. Radical and Palladium-Catalyzed Deoxygenation of the Allylic Alcohol Systems in the Sugar Moiety of Pyrimidine Nucleosides§,1

A. Matsuda, A. Kakefuda, Y. Yoshimura, 1992 .

Nucleosides and nucleotides. 132. Synthesis and biological evaluations of ring-expanded oxetanocin analogues: Purine and pyrimidine analogues of 1,4-anhydro-2-deoxy-d-arabitol and 1,4-anhydro-2-deoxy-3-hydroxymethyl-d-arabitol

S. Shuto, A. Matsuda, Takuma Sasaki, 1994 .

Nucleosides and nucleotides. 116. Convenient syntheses of 3-deazaadenosine, 3-deazaguanosine, and 3-deazainosine via ring closure of 5-ethynyl-1-β-D-ribofuranosylimidazole-4-carboxamide or -carbonitrile

N. Minakawa, A. Matsuda, 1993 .

A Novel Anticancer Ribonucleoside, 1-(3-C-Ethynyl-β-D-ribo-pentofuranosyl)Cytosine, Enhances Radiation-Induced Cell Death in Tumor Cells

A. Matsuda, O. Inanami, M. Kuwabara, 2004, Radiation research.

2-thiouridine is a broad-spectrum antiviral nucleoside analogue against positive-strand RNA viruses

A. Matsuda, N. Maeda, Y. Matsuura, 2022, bioRxiv.

Conversion of guanosine into 2-aminomethylinosine (2-homoguanosine)

A. Matsuda, K. Satoh, T. Miyasaka, 1984 .

Nucleosides and nucleotides. 183. Synthesis of 4'alpha-branched thymidines as a new type of antiviral agent.

S. Shuto, A. Matsuda, S. Shigeta, 1999, Bioorganic & medicinal chemistry letters.

2-Chlorodeoxyadenosine inhibits the repair of DNA double-strand breaks and does not inhibit the repair of DNA single-strand breaks in X-irradiated Chinese hamster V79 cells.

A. Matsuda, M. Kuwabara, F. Sato, 1991, Chemico-biological interactions.

Induction of DNA double-strand breaks in Chinese hamster V79 cells by 2-chlorodeoxyadenosine.

A. Matsuda, M. Kuwabara, F. Sato, 1989, Chemico-biological interactions.

Synthesis and Characterization of Oligodeoxynucleotides Containing Naphthyridine:Imidazopyridopyrimidine Base Pairs at their Sticky Ends. Application as Thermally Stabilized Decoy Molecules

N. Minakawa, A. Matsuda, Sadao Hikishima, 2006 .

A synthesis of ?-cytidine?

A. Matsuda, Kyoichi A. Watanabe, K. Hirota, 1984 .

Nucleosides and Nucleotides. 184. Synthesis and Conformational Investigation of Anti-Fixed 3-Deaza-3-halopurine Ribonucleosides1,2

N. Minakawa, A. Matsuda, N. Kojima, 1999 .

TGF-β2, Tenascin, and Integrin β1 Expression in Superior Limbic Keratoconjunctivitis

A. Matsuda, H. Matsuda, Y. Tagawa, 1999 .

The systemic administration of an anti-miRNA oligonucleotide encapsulated pH-sensitive liposome results in reduced level of hepatic microRNA-122 in mice.

N. Minakawa, A. Matsuda, H. Harashima, 2014, Journal of controlled release : official journal of the Controlled Release Society.

Synthesis and biological activities of 5-substituted 6-phenylthio and 6-iodouridines, a new class of antileukemic nucleosides.

A. Matsuda, H. Hayakawa, T. Miyasaka, 1983, Chemical & pharmaceutical bulletin.

Triazole-linked dumbbell oligodeoxynucleotides with NF-kappaB binding ability as potential decoy molecules.

A. Matsuda, S. Ichikawa, Masanori Nakane, 2008, The Journal of organic chemistry.

Modular bent DNAs: a new class of artificial DNAs with a protein binding ability.

A. Matsuda, S. Ichikawa, Y. Ueno, 2007, Journal of the American Chemical Society.

Groove modification of siRNA duplexes to elucidate siRNA-protein interactions using 7-bromo-7-deazaadenosine and 3-bromo-3-deazaadenosine as chemical probes.

N. Minakawa, A. Matsuda, N. Yamazaki, 2016, Organic & biomolecular chemistry.

Oligodeoxynucleotides Containing 3‐Bromo‐3‐deazaadenine and 7‐Bromo‐7‐deazaadenine 2′‐Deoxynucleosides as Chemical Probes to Investigate DNA–Protein Interactions

N. Minakawa, A. Matsuda, Naonori Inoue, 2008, Chembiochem : a European journal of chemical biology.

Induction of T --> G and T --> A transversions by 5-formyluracil in mammalian cells.

A. Matsuda, H. Kamiya, N. Murata‐Kamiya, 2002, Mutation research.

Nucleosides and Nucleotides. Part 207: Studies in the Chemical Conversion of the 4-Carboxamide Group of 5-Amino-1-β-d-ribofuranosylimidazole-4-carboxamide (AICA-Riboside). Application for the Synthesis of 1-Deazaguanosine

N. Minakawa, A. Matsuda, N. Kojima, 2000 .

Nucleosides and Nucleotides. Part 184. Synthesis and Conformational Investigation of Antifixed 3‐Deaza‐3‐halopurine Ribonucleosides.

N. Minakawa, A. Matsuda, N. Kojima, 2000 .

Design and synthesis of 4″,6″-unsaturated cyclic ADP-carbocyclic-ribose, a Ca2+-mobilizing agent selectively active in T cells

S. Shuto, A. Matsuda, B. Potter, 2008 .

Design and synthesis of 4″,6″-unsaturated cyclic ADP-carbocyclic ribose as a Ca 2+ -mobilizing agent

S. Shuto, A. Matsuda, B. Potter, 2008 .

Substitution at the 8-position of 3''-deoxy-cyclic ADP-carbocyclic-ribose, a highly potent Ca2+-mobilizing agent, provides partial agonists.

S. Shuto, A. Matsuda, T. Murayama, 2007, Bioorganic & medicinal chemistry.

Synthesis of Cyclic ADP-Carbocylcic-Xylose and its 3′′- O O -Methyl Analogue as Stable and Potent Ca2+-Mobilizing Agents

S. Shuto, A. Matsuda, T. Murayama, 2006, Nucleosides, nucleotides & nucleic acids.

Alternative synthesis of cyclic IDP-carbocyclic ribose. Efficient cyclization of an 8-bromo-N1-[5-(phosphoryl)carbocyclic-ribosyl]inosine 5′-phenylthiophosphate derivative mediated by iodine

S. Shuto, N. Minakawa, A. Matsuda, 1999 .

Synthesis of 6,5'-cyclo-2',5'-dideoxypyrimidine nucleosides (nucleosides and nucleotides. LXXII)

A. Matsuda, T. Ueda, Yukari Suzuki, 1987 .

The unusual 1,4-chelation-controlled nucleophilic addition to aldehydes with high stereoselectivity. A systematic study of stereoselectivity in the addition reaction of carbon nucleophiles to cis -substituted cyclopropanecarbaldehydes

S. Shuto, A. Matsuda, H. Abe, 2004 .

Total synthesis of sandramycin and its analogues via a multicomponent assemblage.

A. Matsuda, S. Ichikawa, H. Takeda, 2014, Organic letters.

Nucleosides and nucleotides. Part 201: Alternative method to synthesize 9-(6,7-dideoxy-β-d-allo-hept-5-ynofuranosyl)adenine, a selective and potent ligand for P3 purinoceptor-like protein: a stereoselective reduction based on sugar puckering of the furanose ring†

N. Minakawa, A. Matsuda, T. Umino, 2000 .

Highly stereoselective addition of Grignard reagents to C -cyclopropylnitrone via the bisected s-trans conformation. An efficient synthesis of PEDC, a potent NMDA receptor antagonist having a cyclopropane structure

S. Shuto, A. Matsuda, Yuji Kazuta, 2000 .

Nucleosides and Nucleotides. 151. Conversion of (Z)-2'-(Cyanomethylene)-2'-deoxyuridines into Their (E)-Isomers via Addition of Thiophenol to the Cyanomethylene Moiety Followed by Oxidative Syn-elimination Reactions(1).

S. Shuto, N. Minakawa, A. Matsuda, 1996, The Journal of organic chemistry.

Revisited Mechanistic Implications of the Joullié-Ugi Three-Component Reaction.

A. Matsuda, S. Ichikawa, Akira Katsuyama, 2016, Organic letters.

Highly stereoselective grignard addition to cis-substituted C-cyclopropylaldonitrones. The bisected s-trans transition state can be stabilized effectively by the Lewis acid-coordination.

S. Shuto, A. Matsuda, H. Abe, 2004, The Journal of organic chemistry.

One-Pot Conversion of α,β-Unsaturated Alcohols into the Corresponding Carbon-Elongated Dienes with a Stable Phosphorus Ylide−BaMnO4 System. Synthesis of 6‘-Methylene Derivatives of Neplanocin A as Potential Antiviral Nucleosides. New Neplanocin Analogues. 111

S. Shuto, S. Niizuma, A. Matsuda, 1998 .

Nucleosides and nucleotides. 159. Synthesis of thietane nucleosides via the Pummerer reaction as a key step

A. Matsuda, Y. Yamagata, S. Fujii, 1996 .

Synthesis and biological activity of conformationally restricted analogues of milnacipran: (1S, 2R)-1-phenyl-2-[(R)-1-amino-2-propynyl]-N,N- diethylcyclopropanecarboxamide is a novel class of NMDA receptor channel blocker.

S. Shuto, A. Matsuda, H. Imoto, 1998, Journal of medicinal chemistry.

Nucleoside natural products and related analogs with potential therapeutic properties as antibacterial and antiviral agents

A. Matsuda, S. Ichikawa, 2007 .

Nucleosides and Nucleotides. 140. Synthesis and Antileukemic Activity of 5-Carbon-Substituted 1-β-d-Ribofuflranosylimidazole-4-Carboxamides # 1

N. Minakawa, A. Matsuda, Takuma Sasaki, 1996 .

Nucleosides and nucleotides. 96. Synthesis and antitumor activity of 5-ethynyl-1-beta-D-ribofuranosylimidazole-4-carboxamide (EICAR) and its derivatives.

N. Minakawa, A. Matsuda, T. Takeda, 1991, Journal of medicinal chemistry.

Synthesis of sugar-modified analogs of bredinin (mizoribine), a clinically useful immunosuppressant, by a novel photochemical imidazole ring-cleavage reaction as the key step

S. Shuto, A. Matsuda, M. Fukuoka, 2000 .

Nucleosides and nucleotides. 177. 9-(6,7-dideoxy-beta-D-allo-hept-5- ynofuranosyl)adenine: a selective and potent ligand for P3 purinoceptor-like protein.

N. Minakawa, A. Matsuda, Y. Yoshimura, 1998, Journal of medicinal chemistry.

Expansion of Antibacterial Spectrum of Muraymycins toward Pseudomonas aeruginosa.

A. Matsuda, Yoshikazu Tanaka, M. Sakagami, 2014, ACS medicinal chemistry letters.

Mechanistic analysis of muraymycin analogues: a guide to the design of MraY inhibitors.

A. Matsuda, D. Mengin-Lecreulx, A. Bouhss, 2011, Journal of medicinal chemistry.

Synthesis of L-epi-capreomycidine derivatives via C-H amination.

A. Matsuda, S. Ichikawa, Tetsuya Tanino, 2011, Organic letters.

Development of Antibacterial Agents Active Against Drug-Resistant Bacterial Pathogens Based on Total Synthesis of Nucleoside Natural Products

A. Matsuda, S. Ichikawa, Tetsuya Tanino, 2012 .

Synthesis of Tunicaminyluracil Derivatives

A. Matsuda, S. Ichikawa, 2004, Nucleosides, nucleotides & nucleic acids.

The First Synthesis of Herbicidin B. Stereoselective Construction of the Tricyclic Undecose Moiety by a Conformational Restriction Strategy Using Steric Repulsion between Adjacent Bulky Silyl Protecting Groups on a Pyranose Ring

S. Shuto, A. Matsuda, S. Ichikawa, 1999 .

A novel aldol-type C-glycosidation reaction promoted by samarium diiodide. Regioselective generation of a ulose-1-enolate from phenyl 3,4,6-tri-O-benzyl-1-thio-β-d-arabino-hexopyranosid-2-ulose

S. Shuto, A. Matsuda, S. Ichikawa, 1998 .

Nucleosides and Nucleotides. 163. Synthesis of 3‘-β-Branched Uridine Derivatives via Intramolecular Reformatsky-Type Reaction Promoted by Samarium Diiodide1

S. Shuto, N. Minakawa, A. Matsuda, 1997 .

Synthesis of the C-glycosidic analog of adenophostin A, a potent IP3 receptor agonist, using a temporary silicon-tethered radical coupling reaction as the key step

S. Shuto, A. Matsuda, H. Abe, 2000 .

Nucleosides and Nucleotides. Part 95. Improved Synthesis of 1‐(2‐Azido‐ 2‐deoxy‐β‐D‐arabinofuranosyl)cytosine (Cytarazid) and ‐thymine. Inhibitory Spectrum of Cytarazid on the Growth of Various Human Tumor Cells in vitro.

A. Matsuda, T. Ueda, T. Sasaki, 1991 .

Nucleosides and nucleotides. 95. Improved synthesis of 1-(2-azido-2-deoxy-beta-D-arabinofuranosyl)cytosine (cytarazid) and -thymine. Inhibitory spectrum of cytarazid on the growth of various human tumor cells in vitro.

A. Matsuda, T. Ueda, T. Sasaki, 1991, Journal of medicinal chemistry.

Synthesis of C-glycosyl pyrrolo[3,4-c]carbazole-1,3(2H,6H)-diones as a scaffold for check point kinase 1 inhibitors.

A. Matsuda, S. Ichikawa, Nana Tatebayashi, 2013, The Journal of organic chemistry.

An efficient method for the preparation of 1'alpha-branched-chain sugar pyrimidine ribonucleosides from uridine: the first conversion of a natural nucleoside into 1'-substituted ribonucleosides.

S. Shuto, A. Matsuda, T. Kodama, 2001, Chemistry.

Development of versatile cis- and trans-dicarbon-substituted chiral cyclopropane units: synthesis of (1S,2R)- and (1R,2R)-2-aminomethyl-1-(1H-imidazol-4-yl)cyclopropanes and their enantiomers as conformationally restricted analogues of histamine.

S. Shuto, A. Matsuda, Yuji Kazuta, 2002, The Journal of organic chemistry.

Synthesis of 2,3- and 3,4-methanoamino acid equivalents with stereochemical diversity and their conversion into the tripeptide proteasome inhibitor belactosin a and its highly potent cis-cyclopropane stereoisomer.

S. Shuto, A. Matsuda, H. Yokosawa, 2008, Organic letters.

Synthesis of 1-arylpiperazyl-2-phenylcyclopropanes designed as antidopaminergic agents: cyclopropane-based conformationally restricted analogs of haloperidol.

S. Shuto, A. Matsuda, S. Yamada, 2008, Bioorganic & medicinal chemistry.

Radical reactions with 2-bromobenzylidene group, a protecting/radical-translocating group for the 1,6-radical hydrogen transfer reaction.

S. Shuto, A. Matsuda, S. Hirano, 2006, Organic letters.

Radical hydrogen abstraction–cyclization with a 2-bromovinylsilyl group as a bifunctional tether

S. Shuto, A. Matsuda, M. Sukeda, 2005 .

A Novel Synthesis of 2‘-Modified 2‘-Deoxy-4‘-thiocytidines from d-Glucose1

A. Matsuda, Takuma Sasaki, H. Satoh, 1997 .

Selective detection of 5-formyl-2'-deoxyuridine, an oxidative lesion of thymidine, in DNA by a fluorogenic reagent.

A. Matsuda, Kousuke Sato, W. Hirose, 2010, Angewandte Chemie.

Synthesis of 8-alkyladenosines, 8,2'-anhydro-8-hydroxymethyl-9-(β-D-arabinofuranosyl)adenine and related compounds (nucleosides and nucleotides. LVIII)

A. Matsuda, Y. Nomoto, T. Ueda, 1985 .

Synthesis and Conformational Studies of O 5′, 6-Methanouridine—A New Type of Pyrimidine Cyclonucleoside

S. A. Patil, A. Matsuda, R. Klein, 1992 .

Control of α/β Stereoselectivity in Lewis Acid Promoted C‐Glycosidations Using a Controlling Anomeric Effect Based on the Conformational Restriction Strategy

S. Shuto, A. Matsuda, H. Abe, 2003 .

Highly alpha- and beta-selective radical C-glycosylation reactions using a controlling anomeric effect based on the conformational restriction strategy. A study on the conformation-anomeric effect-stereoselectivity relationship in anomeric radical reactions.

S. Shuto, A. Matsuda, H. Abe, 2001, Journal of the American Chemical Society.

Nucleosides and Nucleotides. 232. Synthesis of 2′-C-Methyl-4′-thiocytidine: Unexpected Anomerization of the 2′-Keto-4′-thionucleoside Precursor

N. Minakawa, A. Matsuda, D. Kaga, 2005, Nucleosides, nucleotides & nucleic acids.

Nucleosides and nucleotides. 124. Chemical reactivity of the sugar moiety of 2′-deoxy-2′-methylidene pyrimidine nucleosides: Synthesis of 3′-amino-2′,3′-dideoxy-2′-methylidene pyrimidine nucleosides via [2,3]-sigmatropic rearrangement of allylic selenides as potential antitumor agents

S. Shuto, A. Matsuda, Abdalla E A Hassan, 1994 .

Design, synthesis, and antineoplastic activity of 2'-deoxy-2'-methylidenecytidine.

A. Matsuda, A. Fujii, T. Ueda, 1988, Journal of medicinal chemistry.

An efficient synthesis of beta-C-glycosides based on the conformational restriction strategy: Lewis acid promoted silane reduction of the anomeric position with complete stereoselectivity.

S. Shuto, A. Matsuda, H. Abe, 2004, Organic letters.

A One-Pot Method for the Stereoselective Introduction of a Vinyl Group via an Atom-Transfer Radical-Cyclization Reaction with a Diphenylvinylsilyl Group as a Temporary Connecting Tether. Synthesis of 4‘α-C-Vinylthymidine, a Potent Antiviral Nucleoside1

A. Matsuda, I. Sugimoto, and Satoshi Shuto, 1999 .

SYNTHESIS AND REACTION OF NUCLEOSIDES CONTAINING SULFUR FUNCTIONS IN THE SUGAR PORTION

A. Matsuda, H. Inoue, T. Ueda, 1978 .

Total synthesis of caprazol, a core structure of the caprazamycin antituberculosis antibiotics.

A. Matsuda, S. Ichikawa, S. Hirano, 2005, Angewandte Chemie.

Effect of Methyl Substitution in 1,2-Ethanediaminenickel(II) Complexes upon Their Thermal Stabilities

A. Matsuda, Masatatsu Suzuki, A. Uehara, 1985 .

Nucleosides and nucleotides. 97. Synthesis of new broad spectrum antineoplastic nucleosides, 2'-deoxy-2'-methylidenecytidine (DMDC) and its derivatives.

A. Matsuda, M. Tanaka, T. Ueda, 1991, Journal of medicinal chemistry.

A convenient method for the selective acylation of guanine nucleosides

A. Matsuda, K. Watanabe, T. Miyasaka, 1986 .

Synthesis and Optical Properties of 2'-Deoxy-8, 2'-methanoguanosine

A. Matsuda, T. Miyasaka, Kazuyuki Watanabe, 1989 .

Synthesis of 8, 2'-Methanoguanosine and 9-(α-D-Arabinofuranosyl)-8, 2'-methanoguanine (Nucleosides and Nucleotides. LXVII.)

A. Matsuda, T. Ueda, H. Usui, 1986 .

An improved large scale synthesis of 1,4-anhydro-4-thio-d-ribitol

N. Minakawa, A. Matsuda, Yuka Kato, 2003 .

Synthesis of 1-0-[(3S,4R)-3-hydroxytetrahydrofuran-4-yl]-α-D-glucopyranoside 3,4,3′-trisphosphate as a novel potent IP3 receptor ligand

S. Shuto, A. Matsuda, Y. Ueno, 1998 .

Conformational Restriction by Repulsion between Adjacent Substituents on a Cyclopropane Ring: Design and Enantioselective Synthesis of 1-Phenyl-2-(1-aminoalkyl)-N,N-diethylcyclopropanecarboxamides as Potent NMDA Receptor Antagonists

S. Shuto, A. Matsuda, S. Ono, 1996 .

Development of the carboxamide protecting group, 4-(tert-butyldimethylsiloxy)-2-methoxybenzyl.

A. Matsuda, S. Ichikawa, K. Muranaka, 2011, The Journal of organic chemistry.

Nucleosides and Nucleotides. 158. 1-(3-C-Ethynyl-β-d-ribo-pentofuranosyl)- cytosine, 1-(3-C-Ethynyl-β-d-ribo-pentofuranosyl)uracil, and Their Nucleobase Analogues as New Potential Multifunctional Antitumor Nucleosides with a Broad Spectrum of Activity1

M. Fukushima, A. Matsuda, H. Hattori, 1996 .

Synthesis of derivatives of (1S,2R)-1-phenyl-2-[(S)-1-aminopropyl]-N,N-diethylcyclopropanecarboxamide (PPDC) modified at the 1-aromatic moiety as novel NMDA receptor antagonists: the aromatic group is essential for the activity.

S. Shuto, A. Matsuda, R. Tsujita, 2002, Bioorganic & medicinal chemistry.

Conformational analysis of the NMDA receptor antagonist (1S,2R)-1-phenyl-2-[(S)-1-aminopropyl]-N,N-diethylcyclopropanecarboxamide (PPDC) designed by a novel conformational restriction method based on the structural feature of cyclopropane ring.

S. Shuto, A. Matsuda, Tamotsu Yamamoto, 2002, Chemical & pharmaceutical bulletin.

Synthesis of (1S,2R)-1-phenyl-2-[(S)-1-aminopropyl]-N,N-diethylcyclopropanecarboxamide (PPDC) derivatives modified at the carbamoyl moiety as a new class of NMDA receptor antagonists.

S. Shuto, A. Matsuda, R. Tsujita, 2002, Bioorganic & medicinal chemistry.

Synthesis of (1S,2R)-1-phenyl-2-[(S)-1-aminoalkyl]-N,N-diethylcyclopropanecarboxamides as novel NMDA receptor antagonists having a unique NMDA receptor subtype selectivity

S. Shuto, A. Matsuda, R. Tsujita, 2002 .

Synthesis of (+)- and (−)-milnaciprans and their conformationally restricted analogs

S. Shuto, A. Matsuda, S. Ono, 1996 .

Highly stereoselective nucleophilic addition to cyclopropyl carbonyls: The facial selectivity in the cyclopropyl ketones is opposite to that in the corresponding aldehyde

S. Shuto, A. Matsuda, S. Ono, 1996 .

Alkyl addition reaction of pyrimidine 2'-ketonucleosides: synthesis of 2'-branched-chain sugar pyrimidine nucleosides (nucleosides and nucleotides. LXXXI.

A. Matsuda, H. Itoh, T. Ueda, 1988, Chemical & pharmaceutical bulletin.

Radical deoxygenation of tert-alcohols in 2'-branched-chain sugar pyrimidine nucleosides: synthesis and antileukemic activity of 2'-deoxy-2' (S)-methylcytidine.

A. Matsuda, H. Itoh, T. Ueda, 1987, Chemical & pharmaceutical bulletin.

Synthesis of galactose-linked uridine derivatives with simple linkers as potential galactosyltransferase inhibitors

A. Matsuda, S. Ichikawa, S. Murata, 2005 .

Practical Synthesis of 4′‐Thioribonucleosides Starting from D‐Ribose

N. Minakawa, A. Matsuda, 2014, Current protocols in nucleic acid chemistry.

Stereoselective synthesis of α- and β-C-glucosides via radical cyclization with an allylsilyl tether. Control of the stereoselectivity by changing the conformation of the pyranose ring

S. Shuto, A. Matsuda, H. Abe, 2000 .

Practical synthesis of 2'-deoxy-4'-thioribonucleosides: substrates for the synthesis of 4'-thioDNA.

N. Minakawa, A. Matsuda, Naonori Inoue, 2005, The Journal of organic chemistry.

Synthesis of 3-methylpseudouridine and 2'-deoxy-3-methyl-pseudouridine.

A. Matsuda, K. Watanabe, K. Pankiewicz, 1982, Carbohydrate research.

Nucleosides and nucleotides. Part 212: Practical large-scale synthesis of 1-(3-C-ethynyl-β-d-ribo-pentofuranosyl)cytosine (ECyd), a potent antitumor nucleoside. Isobutyryloxy group as an efficient anomeric leaving group in the Vorbrüggen glycosylation reaction ☆

S. Shuto, A. Matsuda, T. Asao, 2002 .

Nucleosides and nucleotides. 185. Synthesis and biological activities of 4'alpha-C-branched-chain sugar pyrimidine nucleosides.

S. Shuto, A. Matsuda, S. Shigeta, 1999, Journal of medicinal chemistry.

Nucleosides and nucleotides. 180. Synthesis and antitumor activity of nucleosides that have a hydroxylamino group instead of a hydroxyl group at the 2'- or 3'-position of the sugar moiety.

A. Matsuda, A. Ogawa, M. Tanaka, 1998, Journal of medicinal chemistry.

Stereo- and Regioselective Introduction of 1- or 2-Hydroxyethyl Group via Intramolecular Radical Cyclization Reaction with a Novel Silicon-Containing Tether. An Efficient Synthesis of 4'alpha-Branched 2'-Deoxyadenosines(1).

S. Shuto, N. Minakawa, A. Matsuda, 1998, The Journal of organic chemistry.

Synthesis of L-enantiomers of 4'-thioarabinofuranosyl pyrimidine nucleosides.

A. Matsuda, H. Satoh, Y. Yoshimura, 1998, Bioorganic & medicinal chemistry letters.

Establishment of CHO cell lines expressing four N‐methyl‐D‐aspartate receptor subtypes and characterization of a novel antagonist PPDC

S. Shuto, A. Matsuda, M. Mishina, 2001, FEBS letters.

A facile enzymatic synthesis of 5'-(3-sn-phosphatidyl)nucleosides and their antileukemic activities.

S. Shuto, A. Matsuda, S. Ueda, 1988, Chemical & pharmaceutical bulletin.

Stereochemical diversity-oriented conformational restriction strategy. Development of potent histamine H3 and/or H4 receptor antagonists with an imidazolylcyclopropane structure.

S. Shuto, A. Matsuda, S. Yamada, 2006, Journal of medicinal chemistry.

Nucleosides and nucleotides. 155. synthesis, antitumor effects, and possible enzymatic activation mechanism of 5′-phosphatidyl-2′-deoxy-2′-methylenecytidine (DMDC)

S. Shuto, A. Matsuda, A. Fujii, 1996 .

Nucleosides and nucleotides. 150. Enzymatic synthesis of 5′-phosphatidyl derivatives of (CNDAC) and their notable antitumor effects in mice1

S. Shuto, A. Matsuda, K. Hanaoka, 1996 .

Nucleosides and nucleotides--CXXXVII. Antitumor phospholipids with 5-fluorouridine as a cytotoxic polar-head: synthesis of 5'-phosphatidyl-5-fluorouridines by phospholipase D-catalyzed transphosphatidylation.

S. Shuto, A. Matsuda, A. Sakai, 1995, Bioorganic & medicinal chemistry.

New Neplanocin Analogues II. Enzymatic One-Step Synthesis and Antitumor Activity of 6′-(3-sn-Phosphatidyl)Neplanocin a Derivatives

S. Shuto, A. Matsuda, Tetsu Saito, 1992 .

Nucleic Acids

L. Lankiewicz, A. Kozaki, T. Gotoh, 2007 .

Pharmacology Of A Unique Adenosine Binding Site In Rat Brain Using A Selective Ligand

A. Matsuda, H. Nakata, K. Yoshioka, 2001, Clinical and experimental pharmacology & physiology.

Effect of 9‐(6,7‐Dideoxy‐β‐D‐Allo‐Hept‐5‐Ynofuranosyl)Adenine On Noradrenaline Release From Vascular Sympathetic Nerves

N. Minakawa, A. Matsuda, M. Kunitomo, 2001, Clinical and experimental pharmacology & physiology.

Synthesis of stable and cell-type selective analogues of cyclic ADP-ribose, a Ca(2+)-mobilizing second messenger. Structure--activity relationship of the N1-ribose moiety.

S. Shuto, A. Matsuda, B. Potter, 2005, Journal of the American Chemical Society.

Polydeoxyaminohexopyranosylnucleosides. Synthesis of 1-(2,3,4-Trideoxy-3-nitro-β-D-erythro- and threo-hexopyranosyl)-uracils from Uridine 1

A. Matsuda, Kyoichi A. Watanabe, 1996 .

New neplanocin analogues. 7. Synthesis and antiviral activity of 2-halo derivatives of neplanocin A.

E. De Clercq, S. Shuto, A. Matsuda, 1996, Journal of medicinal chemistry.

Thermal stability and nuclease-resistance properties of oligonucleotides having an aminoalkyl side chain at the nucleobase and sugar moieties

A. Matsuda, A. Takénaka, Y. Ueno, 2004 .

Antitumor activity of a novel orally effective nucleoside, 1-(2-deoxy-2-fluoro-4-thio-beta-D-arabinofuranosyl)cytosine.

A. Matsuda, Y. Yoshimura, M. Tanaka, 1998, Cancer letters.

Molecular Conformation of 2′-Deoxy-2′-methylidene-cytidine: A Potent Antineoplastic Nucleoside

A. Matsuda, K. Tomita, T. Ueda, 1992 .

Selective recognition of unnatural imidazopyridopyrimidine:naphthyridine base pairs consisting of four hydrogen bonds by the Klenow fragment.

N. Minakawa, A. Matsuda, Mayumi Takahashi, 2009, Journal of the American Chemical Society.

Synthesis and properties of oligonucleotides containing 5-formyl-2'-deoxycytidine: in vitro DNA polymerase reactions on DNA templates containing 5-formyl-2'-deoxycytidine.

A. Matsuda, Y. Ueno, N. Karino, 2001, Nucleic acids research.

Amplification of depolarization‐induced and ryanodine‐sensitive cytosolic Ca2+ elevation by synthetic carbocyclic analogs of cyclic ADP‐ribose and their antagonistic effects in NG108‐15 neuronal cells

S. Shuto, A. Matsuda, H. Higashida, 2005, Journal of neurochemistry.

INHIBITORS OF THYMIDYLATE SYNTHETASE

Y. Wataya, A. Matsuda, D. Santi, 1979 .

Expression of macrophage migration inhibitory factor in rat retina and its immunohistochemical localization 1 This research was supported in part by grants from the Ministry of Education, Science and Culture of Japan, The Akiyama Foundation and The Ohyama Foundation. 1

Jun Nishihira, A. Matsuda, Kazuhiko Yoshida, 1997, Journal of Neuroimmunology.

Free-radical reactions induced by OH-radical attack on cytosine-related compounds: a study by a method combining ESR, spin trapping and HPLC.

A. Matsuda, M. Kuwabara, F. Sato, 1990, Nucleic Acids Research.

Photochemical cyclisation of 2',3'-0-isopropylidene-8-phenylthioadenosine to the 8,5'(R)- and 8,5'(S)-cycloadenosines (nucleosides and nucleoti

A. Matsuda, T. Ueda, M. Tezuka, 1978 .

Conformational and inframolecular studies of the protonation of adenophostin analogues lacking the adenine moiety.

S. Shuto, A. Matsuda, C. Maechling, 2004, Biochimica et biophysica acta.

Interaction of thymidylate synthetase with 5-nitro-2'-deoxyuridylate.

Y. Wataya, A. Matsuda, D. Santi, 1980, The Journal of biological chemistry.

5-Nitro-2'-deoxyuridylate: a mechanism-based inhibitor of thymidylate synthetase.

Y. Wataya, A. Matsuda, D. Santi, 1978, Biochemical and biophysical research communications.

Novel nikkomycin analogues: inhibitors of the fungal cell wall biosynthesis enzyme chitin synthase.

A. Matsuda, K. Iwase, J. Uda, 2000, Bioorganic & medicinal chemistry letters.

A method for designing conformationally restricted analogues based on allylic strain: synthesis of a novel class of noncompetitive NMDA receptor antagonists having the acrylamide structure.

S. Shuto, A. Matsuda, R. Tsujita, 2003, Journal of medicinal chemistry.

Selective transcription of an unnatural naphthyridine:imidazopyridopyrimidine base pair containing four hydrogen bonds with T7 RNA polymerase.

A. Matsuda, Kousuke Sato, Y. Nomura, 2014, Angewandte Chemie.

Nucleosides and Nucleotides. Part 183. Synthesis of 4′α-Branched Thymidines as a New Type of Antiviral Agent.

S. Shuto, A. Matsuda, S. Shigeta, 1999 .

A Novel Synthesis of New Antineoplastic 2‘-Deoxy-2‘-substituted-4‘-thiocytidines

A. Matsuda, Takuma Sasaki, H. Satoh, 1996 .

PCR amplification of 4'-thioDNA using 2'-deoxy-4'-thionucleoside 5'-triphosphates.

N. Minakawa, A. Matsuda, K. Furukawa, 2013, ACS synthetic biology.

Nucleosides and nucleotides. 126. Incorporation of a mutagenic nucleoside, 5-formyl-2′-deoxyuridine, into an oligodeoxyribonucleotide☆

A. Matsuda, E. Ohtsuka, A. Ono, 1993 .

Mutations induced by 5-formyl-2'-deoxyuridine in Escherichia coli include base substitutions that can arise from mispairs of 5-formyluracil with guanine, cytosine and thymine.

E. Seeberg, A. Matsuda, F. Provan, 2001, Mutation research.

5-Formyluracil and its nucleoside derivatives confer toxicity and mutagenicity to mammalian cells by interfering with normal RNA and DNA metabolism.

E. Seeberg, A. Matsuda, A. Klungland, 2001, Toxicology letters.

Formation of 5-formyl-2'-deoxycytidine from 5-methyl-2'-deoxycytidine in duplex DNA by Fenton-type reactions and gamma-irradiation.

A. Matsuda, H. Kamiya, N. Murata‐Kamiya, 1999, Nucleic acids research.

Hydrolytic profile for ester- or amide-linkage by carboxylesterases pI 5.3 and 4.5 from human liver.

K Hirano, Y Usami, A. Matsuda, 1997, Biological & pharmaceutical bulletin.

A new entry to the stereoselective introduction of an ethynyl group by a radical reaction: synthesis of the potential antimetabolite 2'-deoxy-2'-C-ethynyluridine.

S. Shuto, A. Matsuda, S. Ichikawa, 2002, Angewandte Chemie.

New NTP analogs: the synthesis of 4′-thioUTP and 4′-thioCTP and their utility for SELEX

Y. Komatsu, N. Minakawa, A. Matsuda, 2005, Nucleic acids research.

Nucleosides and nucleotides. 160. Synthesis of oligodeoxyribonucleotides containing 5-(N-aminoalkyl)carbamoyl-2'-deoxyuridines by a new postsynthetic modification method and their thermal stability and nuclease-resistance properties.

A. Matsuda, N. Haginoya, A. Ono, 1997, Bioconjugate chemistry.

Synthesis and structural elucidation of 1-(3-C-ethynyl-4-thio-β-D-ribofuranosyl)cytosine (4′-thioECyd)

N. Minakawa, A. Matsuda, Takuma Sasaki, 2002 .

Cyclopropane-based conformational restriction of histamine. (1S,2S)-2-(2-aminoethyl)-1-(1H-imidazol-4-yl)cyclopropane, a highly selective agonist for the histamine H3 receptor, having a cis-cyclopropane structure.

S. Shuto, A. Matsuda, S. Yamada, 2003, Journal of medicinal chemistry.

Nucleosides and Nucleotides. 98. Synthesis and Antitumor Activities of 5-Ethynylimidazole-4-carboxamide and -carbonitrile Derivatives

N. Minakawa, A. Matsuda, Takuma Sasaki, 1990 .

New neplanocin analogues. 10. The conversion of adenosine to neplanocin A, a carbocyclic nucleoside antibiotic with potent antiviral activity

S. Shuto, S. Niizuma, A. Matsuda, 1997 .

First synthesis of fully modified 4'-selenoRNA and 2'-OMe-4'-selenoRNA based on the mechanistic considerations of an unexpected strand break.

N. Minakawa, A. Matsuda, K. Furukawa, 2014, Organic letters.

Practical synthesis of 4′-selenopyrimidine nucleosides using hypervalent iodine

N. Minakawa, A. Matsuda, Y. Inagaki, 2011 .

Synthesis and properties of oligonucleotides containing 4'-selenoribonucleosides.

N. Minakawa, A. Matsuda, Y. Inagaki, 2008, Nucleic acids symposium series.

Synthesis of 4′selenoribo nucleosides

N. Minakawa, A. Matsuda, Y. Inagaki, 2007 .

Nucleosides. 114. 5'-O-Glucuronides of 5-fluorouridine and 5-fluorocytidine. Masked precursors of anticancer nucleosides.

A. Matsuda, K. Watanabe, J. Fox, 1981, Journal of medicinal chemistry.

Synthesis and Structural Elucidation of 1-(3-C-Ethynyl-4-thio-β-D-ribofuranosyl)cytosine (4′-ThioECyd).

N. Minakawa, A. Matsuda, Takuma Sasaki, 2003 .

Cellular and Biochemical Mechanisms of the Resistance of Human Cancer Cells to a New Anticancer Ribo‐nucleoside, TAS‐106

M. Fukushima, A. Matsuda, Y. Murakami, 2002, Japanese journal of cancer research : Gann.

The Stereoselective Synthesis of 4‘-β-Thioribonucleosides via the Pummerer Reaction†

N. Minakawa, A. Matsuda, H. Abe, 2000 .

Antitumor mechanisms and metabolism of the novel antitumor nucleoside analogues, 1-(3-C-ethynyl-β-D-ribo-pentofuranosyl)cytosine and 1-(3-C-ethynyl-β-D-ribo-pentofuranosyl)uracil

M. Fukushima, Y. Wataya, A. Matsuda, 1999, Cancer Chemotherapy and Pharmacology.

Nucleosides and nucleotides. 175. Structural requirements of the sugar moiety for the antitumor activities of new nucleoside antimetabolites, 1-(3-C-ethynyl-beta-D-ribo-pentofuranosyl)cytosine and -uracil1.

M. Fukushima, S. Shuto, A. Matsuda, 1998, Journal of medicinal chemistry.

Cell kill kinetics of an antineoplastic nucleoside, 1-(2-deoxy-2-methylene-beta-D-erythro-pentofuranosyl)cytosine.

A. Matsuda, T. Okumoto, M. Hosoya, 1996, Biochemical pharmacology.

Antitumor activity of 2'-deoxy-2'-methylidenecytidine, a new 2'-deoxycytidine derivative.

A. Matsuda, T. Okumoto, A. Fujii, 1991, Cancer research.

A study on the conformation-anomeric effect-stereoselectivity relationship in anomeric radical reactions, using conformationally restricted glucose derivatives as substrates.

S. Shuto, A. Matsuda, H. Abe, 2003, The Journal of organic chemistry.

An efficient method for preparing fully O-silylated pyranoses conformationally restricted in the unusual 1C4-form

S. Shuto, A. Matsuda, H. Abe, 2001 .

Synthesis of pyrimidine 2'-deoxy ribonucleosides branched at the 2'-position via radical atom-transfer cyclization reaction with a vinylsilyl group as a radical-acceptor tether.

S. Shuto, A. Matsuda, S. Ichikawa, 2000, The Journal of organic chemistry.

Mechanistic Study of the Ring-Enlargement Reaction of (3-Oxa-2-silacyclopentyl)methyl Radicals into 4-Oxa-3-silacyclohexyl Radicals. Evidence for a Pentavalent Silicon-Bridging Radical Transition State in 1,2-Rearrangement Reactions of β-Silyl Radicals

S. Shuto, A. Matsuda, I. Sugimoto, 2000 .

A Novel Ring-Enlargement Reaction of (3-Oxa-2-silacyclopentyl)methyl Radicals into 4-Oxa-3-silacyclohexyl Radicals. Stereoselective Introduction of a Hydroxyethyl Group via Unusual 6-Endo-Cyclization Products Derived from 3-Oxa-4-silahexenyl Radicals and Its Application to the Synthesis of a 4‘-α-Br

S. Shuto, A. Matsuda, M. Kanazaki, 1997 .

Crystal structures of DNA:DNA and DNA:RNA duplexes containing 5-(N-aminohexyl)carbamoyl-modified uracils reveal the basis for properties as antigene and antisense molecules

J. Kondo, A. Matsuda, A. Takénaka, 2007, Nucleic acids research.

Nucleoside analogs as a radiosensitizer modulating DNA repair, cell cycle checkpoints, and apoptosis

A. Matsuda, O. Inanami, M. Kuwabara, 2020, Nucleosides, nucleotides & nucleic acids.

Synthesis and anti-dengue virus activity of 5-ethynylimidazole-4-carboxamide (EICA) nucleotide prodrugs.

N. Minakawa, A. Matsuda, Y. Orba, 2021, Chemical & pharmaceutical bulletin.

The antihypertensive effect of 2-alkynyladenosines and their selective affinity for adenosine A2 receptors.

A. Matsuda, K. Aihara, Y. Watanabe, 1991, European journal of pharmacology.

Nucleosides and nucleotides. 127. A novel and convenient post-synthetic modification method for the synthesis of oligodeoxyribonucleotides carrying amino linkers at the 5-position of 2′-deoxyuridine ☆

N. Minakawa, A. Matsuda, N. Haginoya, 1994 .

Nucleosides. 121. Improved and General Synthesis of 2′-Deoxy C-Nucleosides. Synthesis of 5-(2-Deoxy-β-D-erythro-pentofuranosyl)uracil, -1-methyluracil, -1,3-dimethyluracil, and -isocytosine

A. Matsuda, Kyoichi A. Watanabe, K. Pankiewicz, 1982 .

Nucleosides and Nucleotides. Part 167. New Neplanocin Analogues. Part 10. The Conversion of Adenosine to Neplanocin A, a Carbocyclic Nucleoside Antibiotic with Potent Antiviral Activity.

S. Shuto, S. Niizuma, A. Matsuda, 1998 .

New neplanocin analogues. VIII. Synthesis and biological activity of 6'-C-ethyl, -ethenyl, and -ethynyl derivatives of neplanocin A.

E. De Clercq, S. Shuto, A. Matsuda, 1997, Chemical & pharmaceutical bulletin.

New neplanocin analogues. IX. A practical preparation of (6'R)-6'-C-methylneplanocin A (RMNPA), a potent antiviral agent, and the determination of its 6'-configuration. Diastereoselective deamination by adenosine deaminase.

S. Shuto, A. Matsuda, S. Yaginuma, 1997, Chemical & pharmaceutical bulletin.

New Neplanocin Analogues. V. A Potent Adenosylhomocysteine Hydrolase Inhibitor Lacking Antiviral Activity. Synthesis And Antiviral Activity Of 6″-Carboxylic Acid Derivatives Of Neplanocin A 1

A. Matsuda, S. Shigeta, S. Yaginuma, 1996 .

Nucleosides and nucleotides. 142. an alternative synthesis of and its antiviral activity

S. Shuto, A. Matsuda, K. Konno, 1995 .

New neplanocin analogues. IV. 2-Fluoroneplanocin A: an adenosine deaminase-resistant equivalent of neplanocin A.

S. Shuto, A. Matsuda, S. Shigeta, 1994, Chemical & pharmaceutical bulletin.

New neplanocin analogues. III: 6'R-configuration is essential for the antiviral activity of 6'-C-methyl-3-deazaneplanocin A's

S. Shuto, A. Matsuda, S. Shigeta, 1994 .

Design of New Types of Antitumor Nucleosides: The Synthesis and Antitumor Activity of 2′-Deoxy-(2′-C-Substituted)Cytidines

N. Minakawa, A. Matsuda, A. Dan, 1993 .

A facile one-step synthesis of 5'-phosphatidylnucleosides by an enzymatic two-phase reaction

S. Shuto, A. Matsuda, S. Ueda, 1987 .

Nucleosides and Nucleotides. 192. Toward the Total Synthesis of Cyclic ADP-Carbocyclic-Ribose. Formation of the Intramolecular Pyrophosphate Linkage by a Conformation-Restriction Strategy in a Syn-form Using a Halogen Substitution at the 8-Position of the Adenine Ring

S. Shuto, A. Matsuda, Y. Ueno, 2000, Nucleosides, nucleotides & nucleic acids.

Nucleosides and nucleotides. 134. Synthesis of 2′-C-alkynyl-2′-deoxy-1-β-D-arabinofuranosylpyrimidines via radical deoxygenation of tert-propargyl alcohols in the sugar moiety

A. Matsuda, Y. Yoshimura, T. Iino, 1994 .

Nucleosides and nucleotides. 102. Stereoselective radical deoxygenation of tert-propargyl alcohols in sugar moiety of pyrimidine nucleosides: synthesis of 2′-C-alkynyl-2′-deoxy-1-β-d-arabinofuranosylpyrimidines

A. Matsuda, Y. Yoshimura, T. Iino, 1991 .

REACTION OF URACIL NUCLEOSIDES WITH 1-METHYLIMIDAZOLE IN THE PRESENCE OF PHOSPHORYL CHLORIDE : A CONVENIENT METHOD FOR THE SYNTHESIS OF 4-SUBSTITUTED PYRIMIDIN-2 (1H)-ONE NUCLEOSIDES

A. Matsuda, T. Miyasaka, K. Obi, 1985 .

Nucleosides and nucleotides. 191

S. Shuto, A. Matsuda, M. Nomura, 1999 .

Synthesis of 6,1′-propanouridine, fixed in syn-conformation by a spiro-carbon bridge

A. Matsuda, Y. Yoshimura, T. Ueda, 1991 .

Alternative Synthesis of 2'-Deoxy-6, 2'-methano-pyrimidine Nucleosides : Nucleosides and Nucleotides. XC

A. Matsuda, Y. Yoshimura, T. Ueda, 1990 .

Synthesis of 6, 6'-Cyclo-5', 6'-dideoxy-1-(β-D-allofuranosyl)cytosine and Related Nucleosides : Nucleosides and Nucleotides.LXXXVIII)

A. Matsuda, Y. Yoshimura, T. Ueda, 1989 .

Synthesis of 6, 3'-Methanocytidine, 6, 3'-Methanouridine, and Their 2'-Deoxyribonucleosides (Nucleosides and Nucleotides. LXXVII)

A. Matsuda, T. Sano, Y. Yoshimura, 1988 .

Synthesis and properties of a novel nucleoside derivative possessing a 2,3,5,6-tetraazabenzo[ cd ]azulene skeleton

N. Minakawa, A. Matsuda, H. Abe, 2010 .

Nucleosides and nucleotides. 141. Chemical stability of a new antitumor nucleoside, 2'-C-cyano-2'-deoxy-1-beta-D-arabino-pentofuranosylcytosine in alkaline medium: formation of 2'-C-cyano-2'-deoxy-1-beta-D-ribo-pentofuranosylcytosine and its antitumor activity.

A. Matsuda, K. Hanaoka, N. Kamo, 1995, Journal of medicinal chemistry.

A Novel Synthesis of 2′-Modified 2′-Deoxy-4′-thiocytidines from D- Glucose.

A. Matsuda, Takuma Sasaki, H. Satoh, 1997 .

In vitro Anti-Herpesvirus Activities of 5-Substituted 2′-Deoxy-2′-Methylidene Pyrimidine Nucleosides

A. Matsuda, H. Machida, S. Sakata, 1993 .

Nucleosides and nucleotides. 121. Synthesis of oligonucleotides carrying linker groups at the 1'-position of sugar residues.

A. Matsuda, A. Dan, A. Ono, 1993, Bioconjugate chemistry.

Nucleosides & nucleotides. 118. Synthesis of oligonucleotides containing a novel 2′-deoxyuridine analogue that carries an aminoalkyl tether at 1′-position; stabilization of duplex formation by an intercalatin group accommodated in the minor groove

A. Matsuda, A. Dan, A. Ono, 1993 .

Nucleosides and Nucleotides. 174. Synthesis of Oligodeoxynucleotides Containing 4‘-C-[2-[[N-(2-Aminoethyl)carbamoyl]oxy]ethyl]thymidine and Their Thermal Stability and Nuclease-Resistance Properties1

S. Shuto, A. Matsuda, N. Kojima, 1998 .

Nucleosides and nucleotides. 152. 1-(3-C-Ethynyl-β-D-ribo-pentofuranosyl)uracil as a broad spectrum antitumor nucleoside

A. Matsuda, H. Hattori, Takuma Sasaki, 1996 .

Nucleosides and nucleotides. LXXVII: Synthesis of 6,3'-methanocytidine, 6,3'-methanouridine, and their 2'-deoxyribonucleosides

A. Matsuda, T. Sano, Y. Yoshimura, 1988 .

Nucleosides and nucleotides. 115. Synthesis of 3-alkyl-3-deazainosines via palladium-catalyzed intramolecular cyclization: A new conformational lock wi

N. Minakawa, A. Matsuda, M. Aoyagi, 1993 .

Synthesis and Biological Activities of 3′-Deoxy-3′-Isocyano, -Isothiocyano, and -Isoselenocyano-thymidines

A. Matsuda, Takuma Sasaki, T. Ueda, 1990 .

Nucleosides. 115. Reaction of 3'-O-mesylthymidine. Formation of 1-(3-azido-2,3-dideoxy-.beta.-D-threo-pentofuranosyl)thymine and its conversion into 6,3'-imino-1-(2,3-dideoxy-.beta.-D-threo-pentofuranosyl)thymine

A. Matsuda, Kyoichi A. Watanabe, J. Fox, 1980 .

Nucleosides and Nucleotides, Part 144 Synthesis and Antiviral Activity of 5‐Substituted (2′S)‐2′‐Deoxy‐2′‐C‐Methylcytidines and ‐uridines[1]

S. Shuto, A. Matsuda, S. Shigeta, 1996 .

Nucleosides and nucleotides. 94. Radical deoxygenation of tert-alcohols in 1-(2-C-alkylpentofuranosyl) pyrimidines: synthesis of (2'S)-2'-deoxy-2'-C-methylcytidine, an antileukemic nucleoside.

A. Matsuda, T. Ueda, T. Sasaki, 1991, Journal of medicinal chemistry.

Carbocyclic inosine as a potent anti-leishmanial agent: the metabolism and selective cytotoxic effects of carbocyclic inosine in promastigotes of Leishmania tropica and Leishmania donovani.

Y. Wataya, A. Matsuda, O. Hiraoka, 1986, Biochemical and biophysical research communications.

The Synthesis, Mutagenic and Pharmacological Activities of 2-Carbon-Substituted Adenosines

A. Matsuda, T. Ueda, 1987 .

Synthesis of 5'-methylenearisteromycin and its 2-fluoro derivative with potent antimalarial activity due to inhibition of the parasite S-adenosylhomocysteine hydrolase.

Y. Kitade, S. Shuto, Hye-Sook Kim, 2005, Organic & biomolecular chemistry.

A facile, alternative synthesis of 4'-thioarabinonucleosides and their biological activities.

A. Matsuda, H. Satoh, Y. Yoshimura, 1997, Journal of medicinal chemistry.

Synthesis of 2'-deoxy-2'-fluoro-4'-thioarabinonucleosides using the Pummerer rearrangement and their biological evaluation.

A. Matsuda, Y. Yoshimura, K. Yamada, 1997, Nucleic Acids Symposium Series.

In vitro and in vivo antitumor activity of a novel nucleoside, 4'-thio-2'-deoxy-2'-methylidenecytidine.

A. Matsuda, H. Satoh, Y. Yoshimura, 1996, Biological & pharmaceutical bulletin.

Nucleosides and nucleotides 179. Ring-expanded purine nucleosides. The synthesis and cytotoxicity of imidazo[4,5-c]azepine nucleosides

N. Minakawa, A. Matsuda, Takuma Sasaki, 1998 .

Nucleosides and nucleotides. 122. 2'-C-cyano-2'-deoxy-1-beta-D-arabinofuranosylcytosine and its derivatives. A new class of nucleoside with a broad antitumor spectrum.

N. Minakawa, A. Matsuda, K. Hanaoka, 1993, Journal of medicinal chemistry.

Role of RNase L in apoptosis induced by 1-(3-C-ethynyl-β-d-ribo-pentofuranosyl)cytosine

M. Fukushima, Y. Kitade, Hye-Sook Kim, 2009, Cancer Chemotherapy and Pharmacology.

A novel apoptotic pathway of 3'-Ethynylcytidine(ECyd) involving the inhibition of RNA synthesis--the possibility of RNase L activated pathway as a target of ECyd.

M. Fukushima, Y. Kitade, Hye-Sook Kim, 2007, Nucleic acids symposium series.

A CRUCIAL ROLE OF URIDINE/CYTIDINE KINASE 2 IN ANTITUMOR ACTIVITY OF 3′-ETHYNYL NUCLEOSIDES

A. Matsuda, Takuma Sasaki, Y. Endo, 2004, Drug Metabolism and Disposition.

1-(3-C-ETHYNYL-β-D-RIBO-PENTOFURANOSYL)CYTOSINE (ECYD, TAS-106)1: ANTITUMOR EFFECT AND MECHANISM OF ACTION

M. Fukushima, A. Matsuda, Takuma Sasaki, 2001 .

New imidazopyridopyrimidine:naphthyridine base-pairing motif, ImN(N):NaO(O), consisting of a DAAD:ADDA hydrogen bonding pattern, markedly stabilize DNA duplexes.

N. Minakawa, A. Matsuda, N. Tarashima, 2011, Chemical communications.

Synthesis and characterization of oligodeoxynucleotides containing a novel tetraazabenzo[cd]azulene:naphthyridine base pair.

N. Minakawa, A. Matsuda, Yasuyuki Hirama, 2011, Bioorganic & medicinal chemistry.

Unnatural imidazopyridopyrimidine:naphthyridine base pairs: selective incorporation and extension reaction by Deep Vent (exo− ) DNA polymerase

N. Minakawa, A. Matsuda, Mayumi Takahashi, 2009, Nucleic acids research.

New base pairing motifs. The synthesis and thermal stability of oligodeoxynucleotides containing imidazopyridopyrimidine nucleosides with the ability to form four hydrogen bonds.

N. Minakawa, A. Matsuda, Takashi Sasaki, 2003, Journal of the American Chemical Society.

Nucleosides and nucleotides. 107. 2-(cycloalkylalkynyl)adenosines: adenosine A2 receptor agonists with potent antihypertensive effects.

A. Matsuda, Y. Watanabe, T. Yamaguchi, 1992, Journal of Medicinal Chemistry.

Antitumor activity and novel DNA‐self‐strand‐breaking mechanism of CNDAC (1‐(2‐C‐cyano‐2‐deoxy‐β‐d‐ARABINO‐Pentofuranosyl) cytosine) and its N4‐palmitoyl derivative (CS‐682)

A. Tomida, T. Tsuruo, Y. Wataya, 1999, International journal of cancer.

A new antitumor nucleoside, 1-(3-C-ethynyl-beta-D-ribo-pentofuranosyl)cytosine (ECyd), is a potent inhibitor of RNA synthesis.

M. Fukushima, Y. Wataya, A. Matsuda, 1999, Nucleosides & nucleotides.

Evidence supporting the activity of 2'-C-cyano-2'-deoxy-1-beta-D-arabino-pentafuranosylcytosine as a terminator in enzymatic DNA-chain elongation.

A. Matsuda, Y. Hayakawa, R. Kawai, 1998, Bioorganic & medicinal chemistry letters.

Nucleosides and nucleotides. 176. 2'-Deoxy-2'-hydroxylaminocytidine: a new antitumor nucleoside that inhibits DNA synthesis although it has a ribonucleoside structure.

S. Shuto, A. Matsuda, O. Inanami, 1998, Bioorganic & medicinal chemistry letters.

Intracellular Metabolism and Action of an Antitumor Nucleoside, 2′-C-Cyano-2′-Deoxy-1-β-d-arabinofuranosylcytosine (CNDAC)

A. Matsuda, W. Plunkett, Peng Huang, 1997 .

1-(3-C-Ethynyl-beta-D-ribo-pentofuranosyl)cytosine (ECyd, TAS-106), a novel potent inhibitor of RNA polymerase, potentiates the cytotoxicity of CDDP in human cancer cells both in vitro and in vivo.

A. Fujioka, M. Fukushima, Y. Wataya, 2009, International Journal of Oncology.

Nucleosides and Nucleotides. Part 152. 1-(3-C-Ethynyl-β-D-ribo- pentofuranosyl)uracil as a Broad Spectrum Antitumor Nucleoside.

A. Matsuda, H. Hattori, M. Tanaka, 1996 .

Nucleosides and nucleotides. 158. 1-(3-C-ethynyl-beta-D-ribo-pentofuranosyl)-cytosine, 1-(3-C-ethynyl-beta-D-ribo-pentofuranosyl)uracil, and their nucleobase analogues as new potential multifunctional antitumor nucleosides with a broad spectrum of activity.

M. Fukushima, A. Matsuda, H. Hattori, 1996, Journal of medicinal chemistry.

Sensitivity of Human Cancer Cells to the New Anticancer Ribo‐nucleoside TAS–106 Is Correlated with Expression of Uridine‐cytidine Kinase 2

F. Nakagawa, M. Fukushima, A. Matsuda, 2002, Japanese journal of cancer research : Gann.

Nucleosides and Nucleotides. 125. Synthesis and Biological Evaluation of 2′,3′-Dideoxy-3′-fluoro-2′-methylidene Pyrimidine Nucleosides

S. Shuto, A. Matsuda, Abdalla E A Hassan, 1994 .

Facile synthesis of 2′-deoxy-2′-arylthiouridines

A. Matsuda, T. Miyasaka, 1983 .

Nucleosides and nucleotides. 100. 2'-C-cyano-2'-deoxy-1-beta-D-arabinofuranosyl-cytosine (CNDAC): design of a potential mechanism-based DNA-strand-breaking antineoplastic nucleoside.

A. Matsuda, Takuma Sasaki, M. Tanaka, 1991, Journal of medicinal chemistry.

Synthesis and Biological Activities of 2′-Modified 4′-Thionucleosides

A. Matsuda, H. Satoh, Y. Yoshimura, 1997 .

Rapid, Stepwise Substitution of Fluorines In 5-Trifluoromethyl-2′-Deoxyuridine by Bisulfite

Y. Wataya, A. Matsuda, H. Hayatsu, 1994 .

Synthesis of 2- and 8-Cyanoadenosines and Their Derivatives : Nucleosides and Nucleotides. XXVII

A. Matsuda, Y. Nomoto, T. Ueda, 1979 .

trans-5-(3,3,3-Trifluoro-1-propenyl-)-2'-deoxyuridylate: a mechanism-based inhibitor of thymidylate synthetase.

Y. Wataya, A. Matsuda, D. Santi, 1979, Journal of medicinal chemistry.

Site-specific introduction of functional groups into phosphodiester oligodeoxynucleotides and their thermal stability and nuclease-resistance properties.

A. Matsuda, Y. Ueno, Y. Nomura, 1997, Nucleic acids research.

Nucleosides and Nucleotides. Part 127. A Novel and Convenient Post‐ Synthetic Modification Method for the Synthesis of Oligodeoxyribonucleotides Carrying Amino Linkers at the 5‐Position of 2′‐Deoxyuridine.

N. Minakawa, A. Matsuda, N. Haginoya, 1994 .

Nucleosides and nucleotides. Part 226: alternate-strand triple-helix formation by 3'-3'-linked oligodeoxynucleotides composed of asymmetrical sequences.

A. Matsuda, H. Kamiya, S. Hoshika, 2004, Bioorganic & medicinal chemistry letters.

Design and synthesis of 5'-deoxy-5'-phenyladenophostin A, a highly potent IP3 receptor ligand.

S. Shuto, A. Matsuda, Y. Kondo, 2006, Organic letters.

INTRACELLULAR Ca2+-MOBILIZING ADENINE NUCLEOTIDES. SYNTHESIS AND BIOLOGICAL ACTIVITY OF CYCLIC ADP-CARBOCYCLIC-RIBOSE AND C-GLYCOSIDIC ANALOG OF ADENOPHOSTIN A

S. Shuto, A. Matsuda, H. Abe, 2001, Nucleosides, nucleotides & nucleic acids.

Inositol 1,4,5‐trisphosphate and adenophostin analogues induce responses in turtle olfactory sensory neurons

S. Shuto, A. Matsuda, Satoshi Shuto, 2000, The European journal of neuroscience.

A NEW METHOD FOR SYNTHESIZING THE ANTINEOPLASTIC NUCLEOSIDES 1-(2-AZIDO-2-DEOXY-β-D-ARABINOFURANOSYL)CYTOSINE (CYTARAZID) AND 1-(2-AMINO-2-DEOXY-β-D-ARABINOFURANOSYL)CYTOSINE (CYTARAMIN) FROM URIDINE

A. Matsuda, T. Ueda, J. Yasuoka, 1989 .

A SIMPLIFIED SYNTHESIS OF 8-SUBSTITUTED PURINE NUCLEOSIDES VIA LITHIATION OF 6-CHLORO-9-(2, 3-O-ISOPROPYLIDENE-β-D-RIBOFURANOSYL) PURINE

A. Matsuda, H. Hayakawa, T. Miyasaka, 1983 .

Nucleosides and Nucleotides. Part 128. (2′S)‐2′‐Deoxy‐2′‐C‐methyl‐5‐ iodouridine (SMIU) as a Novel Potent Anti‐Herpes Virus Agent.

S. Shuto, A. Matsuda, M. Baba, 1994 .

Nucleosides and nucleotides. 170. Synthesis and properties of oligodeoxynucleotides containing 5-[N-[2-[N,N-bis(2-aminoethyl)- amino]ethyl]carbamoyl]-2'-deoxyuridine and 5-[N-[3-[N,N-bis(3-aminopropyl) amino]propyl]carbamoyl]-2'-deoxyuridine.

A. Matsuda, Y. Ueno, M. Mikawa, 1998, Bioconjugate chemistry.

Double-stranded oligonucleotides containing 5-aminomethyl-2'-deoxyuridine form thermostable anti-parallel triplexes with single-stranded DNA or RNA.

Y. Kitade, A. Matsuda, M. Iwata, 2012, Bioorganic & medicinal chemistry letters.

Nucleosides and nucleotides. 218. Alternate-strand triple-helix formation by the 3'-3'-linked oligodeoxynucleotides using a purine motif.

A. Matsuda, S. Hoshika, Y. Ueno, 2003, Bioconjugate chemistry.

Nucleosides and nucleotides. 208. Alternate-strand triple-helix formation by the 3'-3'-linked oligodeoxynucleotides with the anthraquinonyl group at the junction point.

A. Matsuda, S. Hoshika, Y. Ueno, 2001, Bioconjugate chemistry.

Nucleosides and Nucleotides. 182. Synthesis of Branched Oligodeoxynucleotides with Pentaerythritol at the Branch Point and Their Thermal Stabilization of Triplex Formation1

A. Matsuda, Y. Ueno, M. Mikawa, 1999 .

Nucleosides and nucleotides. 162. Facile synthesis of 5′-5′-linked oligodeoxyribonucleotides with the potential for triple-helix formation

A. Matsuda, Aiko Nakagawa, A. Ogawa, 1996 .

Synthesis of adenophostin A analogues conjugating an aromatic group at the 5'-position as potent IP3 receptor ligands.

S. Shuto, A. Matsuda, Y. Kondo, 2006, Journal of medicinal chemistry.

Synthesis of the C-glycosidic analogue of adenophostin A and its uracil congener as potential IP(3) receptor ligands. Stereoselective construction of the C-glycosidic structure by a temporary silicon-tethered radical coupling reaction.

S. Shuto, A. Matsuda, H. Abe, 2000, Journal of Organic Chemistry.

SYNTHESIS OF ADENOPHOSTIN ANALOGUES LACKING THE ADENINE MOIETY AS NOVEL POTENT IP3 RECEPTOR LIGANDS : SOME STRUCTURAL REQUIREMENTS FOR THE SIGNIFICANT ACTIVITY OF ADENOPHOSTIN A

S. Shuto, A. Matsuda, Y. Ueno, 1998 .

Synthesis of 1‐O‐[(3S,4R)‐3‐Hydroxytetrahydrofuran‐4‐yl]‐α‐D‐glucopyranoside 3,4,3′‐Trisphosphate as a Novel Potent IP3 Receptor Ligand.

S. Shuto, A. Matsuda, Y. Ueno, 1998 .

A systematic study of C-glucoside trisphosphates as myo-inositol trisphosphate receptor ligands. Synthesis of beta-C-glucoside trisphosphates based on the conformational restriction strategy.

S. Shuto, A. Matsuda, B. Potter, 2006, Journal of Medicinal Chemistry.

Intracellular Ca2+‐Mobilizing Adenine Nucleotides. Synthesis and Biological Activity of Cyclic ADP‐Carbocyclic‐Ribose and C‐Glycosidic Analogue of Adenophostin A

S. Shuto, A. Matsuda, H. Abe, 2001 .

Synthetic studies of carbocyclic analogs of cyclic ADP-ribose. Formation of a cyclic dimer, a 36-membered-ring product, in the condensation reaction of an 8-bromo-N1-[5-(phenylthiophosphoryl)carbocyclic-ribosyl]inosine 5′-phosphate derivative mediated by AgNO3

S. Shuto, A. Matsuda, Y. Ueno, 1998 .

Nucleosides and Nucleotides. 173. Synthesis of Cyclic IDP-carbocyclic-ribose, a Stable Mimic of Cyclic ADP-ribose. Significant Facilitation of the Intramolecular Condensation Reaction of N-1-(Carbocyclic-ribosyl)inosine 5‘,6‘‘-Diphosphate Derivatives by an 8-Bromo-Substitution at the Hypoxanthine Mo

S. Shuto, A. Matsuda, Y. Ueno, 1998 .

Synthesis and Antitumor Activity of Acyl and Benzyl Types of Prodrugs of 2′-Deoxy-2′-methylidenecytidine

A. Matsuda, A. Fujii, T. Ueda, 1992 .

NUCLEOSIDES. 123. SYNTHESIS OF ANTIVIRAL NUCLEOSIDES: 5-SUBSTITUTED 1-(2-DEOXY-2-HALOGENO-β-D-ARABINOFURANOSYL)CYTOSINES AND -URACILS. SOME STRUCTURE-ACTIVITY RELATIONSHIPS

A. Matsuda, M. Chun, C. K. Chu, 1983 .

Nucleosides and Nucleotides. Part 88. A New Method for Synthesizing the Antineoplastic Nucleosides 1-(2-Azido-2-deoxy-β-D-arabinofuranosyl)cytosine (Cytarazid) and 1-(2-Amino-2-deoxy-β-D-arabinofuranosyl)cytosine (Cytaramin) from Urid

A. Matsuda, T. Ueda, J. Yasuoka, 1990 .

A systematic study of the hydride reduction of cyclopropyl ketones with structurally simplified substrates. highly stereoselective reductions of trans-substituted cyclopropyl ketones via the bisected s-cis conformation.

S. Shuto, A. Matsuda, H. Abe, 2003, The Journal of organic chemistry.

A NOVEL AFFINITY CHROMATOGRAPHY METHOD FOR THE CO-PURIFICATION OF DEOXYCYTIDINE KINASE AND CYTIDINE DEAMINASE

A. Matsuda, Takuma Sasaki, Y. Endo, 2001, Nucleosides, nucleotides & nucleic acids.

Nucleosides-126: Selective methylation of the C-nucleoside, ψ-isocytidine and its 2$́-deoxy analog. Synthesis of 1-methyl, 3-methyl and 4-o-methyl derivatives

A. Matsuda, Kyoichi A. Watanabe, J. Fox, 1984 .

Nucleosides and Nucleotides. 108. Synthesis and Optical Properties of Syn-Fixed Carbon-Bridged Pyrimidine Cyclonucleosides

A. Matsuda, Y. Yoshimura, T. Ueda, 1992 .

The Reaction of 6-Phenylthiouridine with Sulfur Nucleophiles : A Simple and Regiospecific Preparation of 6-Alkylthiouridines and 6-Alkylthiouridylic Acids

A. Matsuda, H. Hayakawa, T. Miyasaka, 1983 .

LITHIATION OF AN IMIDAZOLE NUCLEOSIDE AT THE C-5 POSITION. SYNTHESIS OF 3-DEAZAGUANOSINE FROM URIDINE

A. Matsuda, T. Miyasaka, Hiromichi Tanaka, 1985 .

A SIMPLIFIED SYNTHESIS OF 8-SUBSTITUTED PURINE NUCLEOSIDES VIA LITHIATION OF 6-CHLORO-9-(2,3-O-ISOPROPYLIDENE-β-D-RIBOFURANOSYL)PURINE

A. Matsuda, H. Hayakawa, T. Miyasaka, 1983 .

Nucleosides and nucleotides. 131. Synthesis and properties of oligonucleotides containing 5-formyl-2'-deoxyuridine.

A. Matsuda, A. Ono, H. Nara, 1994, Chemical & pharmaceutical bulletin.

Effects of 2'-O-(trifluoromethyl)adenosine on oligodeoxynucleotide hybridization and nuclease stability.

A. Matsuda, Y. Ueno, N. Nishizono, 1998, Nucleic acids research.

Synthesis of 3'-3'-linked oligonucleotides branched by a pentaerythritol linker and the thermal stabilities of the triplexes with single-stranded DNA or RNA.

Y. Kitade, A. Matsuda, Aya Shibata, 2003, Bioconjugate chemistry.

Antitumor Activity and Pharmacokinetics of TAS‐106, l‐(3‐C‐Ethynyl‐β‐D‐ribo‐pentofuranosyl)cytosine

A. Fujioka, M. Fukushima, A. Matsuda, 2001, Japanese journal of cancer research : Gann.

Synthesis of carbon-bridged 8,5'-cyclopurine nucleosides: Nucleosides and nucleotides—XXIV

A. Matsuda, E. Sugiyama, T. Ueda, 1978 .

The design, synthesis and antileukemic activity of 5-alkynyl-1-beta-D-ribofuranosylimidazole-4-carboxamides.

N. Minakawa, A. Matsuda, T. Ueda, 1988, Chemical & pharmaceutical bulletin.

Nucleosides and Nucleotides. 153. Effects of 2′-α- and 2′-β-Bromo-2′-deoxyadenosine on Oligonucleotide Hybridization and Nuclease Stability

A. Matsuda, A. Ono, Y. Ueno, 1996 .

Nucleosides. 124. 3-Amino-3-deoxyhexopyranosyl Nucleosides. 7. 1-(3-Deoxy-3-Nitro-β-D-glucopyranosyl) Uracil and Its Galactopyranosyl Isomer1

A. Matsuda, M. Chun, Kyoichi A. Watanabe, 1982 .

Insights into the Structures of DNA Damaged by Hydroxyl Radical: Crystal Structures of DNA Duplexes Containing 5-Formyluracil

A. Matsuda, Naoko Abe, M. Tsunoda, 2010, Journal of nucleic acids.

Nucleosides and Nucleotides. 165. Chemical Ligation of Oligodeoxynucleotides Having a Mercapto Group at the 5-Position Of 2′-Deoxyuridine via a Disulfide Bond #

A. Matsuda, Aiko Nakagawa, Y. Ueno, 1998 .

Tris(azidoethyl)amine hydrochloride; a versatile reagent for synthesis of functionalized dumbbell oligodeoxynucleotides.

A. Matsuda, S. Ichikawa, Kousuke Sato, 2013, Organic letters.

Nucleosides and nucleotides. 161. Incorporation of 5-(N-aminoalkyl)carbamoyl-2′-deoxycytidines into oligodeoxyribonucleotides by a convenient post-synthetic modification method

A. Matsuda, N. Haginoya, Y. Ueno, 1996 .

Nucleosides and Nucleotides. Part 121. Synthesis of Oligonucleotides Carrying Linker Groups at the 1′‐Position of Sugar Residues.

A. Matsuda, A. Dan, A. Ono, 1994 .

Synthesis of 1-(2-deoxy-2-C-fluoromethyl-β-D-arabinofuranosyl)cytosine as a potential antineoplastic agent

A. Matsuda, Y. Yoshimura, S. Sakata, 1994 .

Synthesis of C-glycosides via radical cyclization reactions with a vinylsilyl tether. Control of the reaction course by a change in the conformation of the pyranose ring due to steric repulsion between adjacent bulky protecting groups

S. Shuto, A. Matsuda, S. Ichikawa, 1999 .

Synthesis of Oligodeoxynucleotides Containing 4′-C-Aminoalkyl-thymidines and Their Thermal Stability and Nuclease-Resistance Properties

S. Shuto, A. Matsuda, Y. Ueno, 1999 .

Mutagenicity of 5-bromouracil and N6-hydroxyadenine studied by yeast oligonucleotide transformation assay.

V. Noskov, A. Matsuda, A. Ono, 1994, Mutation research.

NUCLEOSIDES AND NUCLEOTIDES 111. THERMAL STABILITY OF OLIGODEOXYRIBONUCLEOTIDE DUPLEXES CONTAINING N6-HYDROXYADENINE IN SUBSTITUTION FOR ADENINE

A. Matsuda, A. Ono, T. Ueda, 1992 .

The synthesis and properties of oligodeoxyribonucleotides containing N6-methoxyadenine.

A. Matsuda, A. Ono, T. Ueda, 1992, Nucleic acids research.

Analysis of 2-amino-N6-hydroxyadenine-induced mutagenesis in phage M13mp2.

A. Matsuda, H. Hayatsu, K. Negishi, 1991, Mutation research.

Synthesis of 6, 5'-Cyclo-5'-deoxy-5' ( R and S ) - (2-hydroxyethyl) -uridines (Nucleosides and Nucleotides. LXXIII)

A. Matsuda, T. Ueda, Yukari Suzuki, 1987 .

SYNTHESIS AND BIOLOGICAL ACTIVITY OF BRANCHED CHAIN-SUGAR NUCLEOSIDES1

A. Matsuda, Y. Yoshimura, T. Ueda, 1989 .

The characterization of cell death induced by 1-(3-C-ethynyl-beta-D-ribo-pentofuranosyl) cytosine (ECyd) in FM3A cells.

M. Fukushima, Y. Wataya, A. Matsuda, 1998, Nucleosides & nucleotides.

2′-C-Cyano-2′-deoxy-1-β-D-arabinofuranosylcytosine (CNDAC): A Mechanism-Based DNA-Strand-Breaking Antitumor Nucleoside1

A. Matsuda, A. Azuma, 1995 .

Nucleosides and nucleotides. XLIII. On the stereoselectivity of alkyl addition reaction of pyrimidine 2'-ketonucleosides.

A. Matsuda, T. Ueda, H. Itoh, 1990 .

Nucleosides and Nucleotides. 130. The Synthesis of Imidazo[4, 5-e][1, 4] Diazepine Nucleosides From N 1-Substituted Inosines

N. Minakawa, A. Matsuda, M. Aoyagi, 1994 .

Conformation of 3-substituted purine nucleoside studied by x-ray crystallography and theoretical calculations

N. Minakawa, A. Matsuda, Y. Yamagata, 1994 .

Nucleosides and Nucleotides. Part 115. Synthesis of 3-Alkyl-3-deazainosines via Palladium-Catalyzed Intramolecular Cyclization: A New Conformational Lock with the Alkyl Group at the 3-Position of the 3-Deazainosine in anti-Conformation.

N. Minakawa, A. Matsuda, M. Aoyagi, 1993 .

Molecular Conformations of Carbon-Bridged Cyclodeoxyadenosines in the Solid State and in Solution.2'-Deoxy-8, 2'-methanoadenosine and 2'-Deoxy-8, 2'-ethanoadenosine

A. Matsuda, Y. Yamagata, K. Tomita, 1992 .

NUCLEOSIDES. 115. REACTION OF 3′-O-MESYLTHYMIDINE. FORMATION OF 1-(3-AZIDO-2,3-DIDEOXY-β-D-THREO-PENTOFURANOSYL)THYMINE AND ITS CONVERSION INTO 6,3′-IMINO-1-(2,3-DIDEOXY-β-D-THREO-PENTOFURANOSYL)THYMINE

A. Matsuda, K. Watanabe, J. Fox, 1980 .

Synthesis and anti-HIV activity of 3'-cyano-2',3'-dideoxythymidine and 3'-cyano-2',3'-didehydro-2',3'-dideoxythymidine

A. Matsuda, H. Nakashima, N. Yamamoto, 1988 .

Synthesis of 5‐Formyl‐2′‐Deoxyuridine and Its Incorporation into Oligodeoxynucleotides

A. Matsuda, Kousuke Sato, W. Hirose, 2008, Current protocols in nucleic acid chemistry.

Nucleosides and Nucleotides. Part 94. Radical Deoxygenation of tert- Alcohols in 1-(2-C-Alkylpentofuranosyl)pyrimidines: Synthesis of (2′S)- 2′-Deoxy-2′-C-methylcytidine, an Antileukemic Nucleoside.

A. Matsuda, Takuma Sasaki, T. Ueda, 1991 .

Synthesis and antiviral activity of 5-substituted (2'S)-2'-deoxy-2'-C-methylcytidines and -uridines.

S. Shuto, A. Matsuda, S. Shigeta, 1996, Archiv der Pharmazie.

Nucleosides and Nucleotides. 143. Synthesis of 5-Amino-4-imidazolecarboxamide (AICA) Deoxyribosides from Deoxyinosines and Their Conversion into 3-Deazapurine Derivatives.

N. Minakawa, A. Matsuda, A. Kiyosue, 1996 .

THERAPEUTIC EFFECT OF INOSINE ANALOGS IN MICE INFECTED WITH LEISHMANIA DONO-VANI OR TR YPANOSOMA GAMBIENSE

Y. Wataya, A. Matsuda, T. Ueda, 1988 .

A Facile, Alternative Synthesis of 4′-Thioarabinonucleosides and Their Biological Activities.

A. Matsuda, H. Satoh, Y. Yoshimura, 1997 .

Nucleosides and Nucleotides. Part 179. Ring‐Expanded Purine Nucleosides. The Synthesis and Cytotoxicity of Imidazo[4,5‐c]azepine Nucleosides.

N. Minakawa, A. Matsuda, Takuma Sasaki, 1999 .

Nucleosides and nucleotides. 117. A transition-state analogue in purine nucleotide biosynthesis: the design and synthesis of an imidazo[4,5-c]azepine nucleoside☆

N. Minakawa, A. Matsuda, Takuma Sasaki, 1993 .

2′/3′‐O‐peptidyl Adenosine as a General Base Catalyst of its Own External Peptidyl Transfer: Implications for the Ribosome Catalytic Mechanism

N. Minakawa, A. Matsuda, S. Acharya, 2005, Chembiochem : a European journal of chemical biology.

Repair of DNA damage induced by the novel nucleoside analogue CNDAG through homologous recombination

A. Matsuda, Xiaojun Liu, Ying-jun Jiang, 2020, Cancer Chemotherapy and Pharmacology.

Molecular basis for G2 arrest induced by 2'-C-cyano-2'-deoxy-1-beta-D-arabino-pentofuranosylcytosine and consequences of checkpoint abrogation.

A. Matsuda, W. Hittelman, Xiaojun Liu, 2005, Cancer research.

[Comprehensive synthetic study of muraymycins toward the development of novel antibacterial agents].

A. Matsuda, S. Ichikawa, Tetsuya Tanino, 2011, Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan.

A nucleoside anticancer drug, 1-(3-C-ethynyl-β-D-ribo-pentofuranosyl)cytosine (TAS106), sensitizes cells to radiation by suppressing BRCA2 expression

M. Fukushima, A. Matsuda, O. Inanami, 2011, Molecular Cancer.

[Antitumor effect and mechanism of a novel multifunctional nucleoside, 3'-ethynylnucleoside, on human cancers].

M. Fukushima, A. Matsuda, K. Eshima, 1997, Gan to kagaku ryoho. Cancer & chemotherapy.

Antitumor effect of a novel multifunctional antitumor nucleoside, 3'-ethynylcytidine, on human cancers.

M. Fukushima, A. Matsuda, M. Tanaka, 1996, Oncology reports.

Nucleosides and Nucleotides. Part 100. 2′-C-Cyano-2′-deoxy-1-β-D- arabinofuranosylcytosine (CNDAC): Design of a Potential Mechanism- Based DNA-Strand-Breaking Antineoplastic Nucleoside.

A. Matsuda, Takuma Sasaki, M. Tanaka, 1992 .

Chemical Screening Identifies EUrd as a Novel Inhibitor Against Temozolomide‐Resistant Glioblastoma‐Initiating Cells

Y. Fujii, A. Matsuda, T. Kondo, 2016, Stem cells.

1‐(3‐C‐Ethynyl‐β‐D‐ribo‐pentofuranosyl)cytosine (ECyd, Tas‐106)1: Antitumor Effect and Mechanism of Action

M. Fukushima, A. Matsuda, Takuma Sasaki, 2001 .

Role of the uridine/cytidine kinase 2 mutation in cellular sensitiveness toward 3′-ethynylcytidine treatment of human cancer cells

M. Fukushima, Hye-Sook Kim, Y. Wataya, 2017, Anti-cancer drugs.

Development Of An Antitumor Adenosine Analog, 3″-Ethynyladenosine

M. Fukushima, A. Matsuda, Takuma Sasaki, 2007, Nucleosides, nucleotides & nucleic acids.

Analysis of single nucleotide polymorphisms in uridine/cytidine kinase gene encoding metabolic enzyme of 3'-ethynylcytidine.

Y. Wataya, A. Matsuda, Hey-Sook Kim, 2002, Nucleic acids research. Supplement.

A New Antitumor Nucleoside, 1-(3-C-Ethynyl-β-D-ribo-pentofuranosyl)cytosine (ECyd), is a Potent Inhibitor of RNA Synthesis

M. Fukushima, Y. Wataya, A. Matsuda, 1999 .

Interaction of tRNA (uracil-5-)-methyltransferase with NO2Ura-tRNA.

A. Matsuda, D. Santi, K. Ivanetich, 1996, Nucleic acids research.

Preface

A. Matsuda, P. Herdewijn, M. Egli, 2012 .

Chemical ligation of oligonucleotides using an electrophilic phosphorothioester

S. Shuto, A. Matsuda, Yoshihiro Ito, 2017, Nucleic acids research.

Design, Characterization, and Application of Imidazopyridopyrimidine:Naphthyridine Base-Pairing Motifs Consisting of Four Hydrogen Bonds

N. Minakawa, A. Matsuda, 2014 .

Nucleosides and Nucleotides. Part 176. 2′-Deoxy-2′-hydroxylaminocytidine: A New Antitumor Nucleoside that Inhibits DNA Synthesis Although it has a Ribonucleoside Structure.

S. Shuto, A. Matsuda, O. Inanami, 1998 .

Nucleosides and Nucleotides. 106. Synthesis and Biological Activity of 1-(2-Deoxy-2-hydroxyimino- or Methoxyimino-β-D-erythro-pentofuranosyl)-thymine and -Cytosine§,1

A. Matsuda, Takuma Sasaki, T. Ueda, 1992 .

Structural basis for the specificity, catalysis, and regulation of human uridine-cytidine kinase.

A. Matsuda, F. Inagaki, N. Suzuki, 2004, Structure.

Synthesis of 2',3'-dideoxy-3'-methylidenethymidine and 2',3'-didehydro-2',3'-dideoxy-3'-methylthymidine: deoxygenation of the allylic alcohol system in 3'-deoxy-3'-methylidene-5-methyluridine

A. Matsuda, T. Ueda, H. Okajima, 1989 .

Nucleosides and Nucleotides. Part 182. Synthesis of Branched Oligodeoxynucleotides with Pentaerythritol at the Branch Point and Their Thermal Stabilization of Triplex Formation.

A. Matsuda, Y. Ueno, M. Mikawa, 1999 .

Unexpected A-form formation of 4′-thioDNA in solution, revealed by NMR, and the implications as to the mechanism of nuclease resistance

N. Minakawa, A. Matsuda, M. Katahira, 2008, Nucleic acids research.

Efficient synthesis of β-C-glucosides via radical cyclization with a silicon tether based on the conformational restriction strategy

S. Shuto, A. Matsuda, Masaru Terauchi, 2005 .

SYNTHESIS AND BIOLOGICAL ACTIVITIES OF CYCLIC ADP-CARBOCYCLIC-RIBOSE AND ITS ANALOGS

S. Shuto, N. Minakawa, A. Matsuda, 2001, Nucleosides, nucleotides & nucleic acids.

Synthesis and characterization of 2′-modified-4′-thioRNA: a comprehensive comparison of nuclease stability

N. Minakawa, A. Matsuda, Mayumi Takahashi, 2009, Nucleic acids research.

8-Aminoadenosine enhances radiation-induced cell death in human lung carcinoma A549 cells.

A. Matsuda, O. Inanami, T. Yamamori, 2011, Journal of radiation research.

Association of RNase L with a Ras GTPase‐activating‐like protein IQGAP1 in mediating the apoptosis of a human cancer cell‐line

Yukio Kitade, Akiko Hiramoto, M. Fukushima, 2010, The FEBS journal.

(ECyd, TAS-106), a novel potent inhibitor of RNA polymerase, potentiates the cytotoxicity of CDDP in human cancer cells both in vitro and in vivo

A. Fujioka, M. Fukushima, Y. Wataya, 2009 .

A CRUCIAL ROLE OF URIDINE/CYTIDINE KINASE 2 IN ANTITUMOR ACTIVITY OF 3 (cid:1) -ETHYNYL NUCLEOSIDES

A. Matsuda, Takuma Sasaki, Y. Endo, 2004 .

Targeting for lymph based on the characteristic oral absorption mechanism for phospholipids. Design, synthesis, and biological activity of 5'-phosphatidyl-FURs as antitumor pseudo-phospholipids.

S. Shuto, A. Matsuda, H. Itoh, 1996 .

Total synthesis of cyclic ADP-carbocyclic-ribose, a stable mimic of Ca2+-mobilizing second messenger cyclic ADP-ribose.

S. Shuto, A. Matsuda, H. Kuroda, 2001, Journal of the American Chemical Society.

Synthesis of 2-Alkynylcordycepins and Evaluation of Their Vasodilating Activity

A. Matsuda, H. Hayakawa, T. Miyasaka, 1998 .

Nucleosides and Nucleotides. Part 125. Synthesis and Biological Evaluation of 2′,3′-Dideoxy-3′-fluoro-2′-methylidene Pyrimidine Nucleosides.

S. Shuto, A. Matsuda, Abdalla E A Hassan, 1995 .

Nucleosides and Nucleotides. 110. [2,3]-Sigmatropic Rearrangement of the Allylic Selenides to Allylic Amines in Sugar Moiety of Pyrimidine Nucleosides: Synthesis of 3'-Amino-2',3'-dideoxy-2'-methylidenecytidine

A. Matsuda, A. Hassan, 1992 .

Anti‐neovascular therapy by liposomal DPP‐CNDAC targeted to angiogenic vessels

S. Shuto, A. Matsuda, N. Oku, 2002, FEBS letters.

Synthesis and Biological Activities of 2′‐Modified 4′‐Thionucleosides.

A. Matsuda, H. Satoh, Y. Yoshimura, 2010 .

Recent Development of anti-HIV Nucleosides

A. Matsuda, 1991 .

Reaction of 6-Methylsulfonylpurine Riboside with Carbon Nucleophiles and the Synthesis of 6-Alkylpurine Nucleosides (Nucleosides and Nucleotides. XXIX)

A. Matsuda, A. Yamane, T. Ueda, 1980 .

SYNTHESIS AND REACTION OF SOME 6‐SUBSTITUTED PYRIMIDINE NUCLEOSIDES *

A. Matsuda, H. Inoue, T. Ueda, 1975, Annals of the New York Academy of Sciences.

Nucleosides and nucleotides. CXIX. Inhibition of DNA-cytosine methylase HhaI by a self-complementary oligonucleotide containing 5-fluorocytosine.

A. Matsuda, A. Ono, T. Ueda, 1993, Biological & pharmaceutical bulletin.

TRANS-5-(3,3,3-TRIFLUORO-1-PROPENYL)-2′-DEOXYURIDYLATE: A MECHANISM-BASED INHIBITOR OF THYMIDYLATE SYNTHETASE

Y. Wataya, A. Matsuda, D. Santi, 1979 .

Nucleosides. 120. Syntheses of 2'-deoxy-.psi.-isocytidine and 2'-deoxy-1-methyl-.psi.-uridine from .psi.-uridine

A. Matsuda, C. K. Chu, Kyoichi A. Watanabe, 1981 .

The systemic administration of an anti-miRNA oligonucleotide encapsulated pH-sensitive liposome results in reduced level of hepatic microRNA-122 in mice.

N. Minakawa, A. Matsuda, H. Harashima, 2014, Journal of controlled release : official journal of the Controlled Release Society.

In vitro optimization of 2′-OMe-4′-thioribonucleoside–modified anti-microRNA oligonucleotides and its targeting delivery to mouse liver using a liposomal nanoparticle

N. Minakawa, A. Matsuda, H. Harashima, 2013, Nucleic acids research.

Mutagenicity of secondary oxidation products of 8-oxo-7,8-dihydro-2'-deoxyguanosine 5'-triphosphate (8-hydroxy-2'- deoxyguanosine 5'-triphosphate).

N. Minakawa, A. Matsuda, H. Harashima, 2011, Mutation research.

Rolling Circle Translation of Circular RNA in Living Human Cells

Minoru Yoshida, Aya Shibata, Yoshihiro Ito, 2015, Scientific Reports.

Study of Modification Pattern–RNAi Activity Relationships by Using siRNAs Modified with 4′‐Thioribonucleosides

N. Minakawa, A. Matsuda, S. Hoshika, 2007, Chembiochem : a European journal of chemical biology.

Intracellular stability of 2′-OMe-4′-thioribonucleoside modified siRNA leads to long-term RNAi effect

N. Minakawa, A. Matsuda, H. Harashima, 2012, Nucleic acids research.

Cisplatin resistance in human lung cancer cells is linked with dysregulation of cell cycle associated proteins.

A. Matsuda, R. Yumoto, M. Takano, 2015, Life sciences.

1 RNA interference ( RNAi ) induced by siRNAs modified with 4 ’-thioribonucleosides in cultured mammalian cells

A. Matsuda, Kamiya, Harashima, 2017 .

RNA interference induced by siRNAs modified with 4′‐thioribonucleosides in cultured mammalian cells

Hideyoshi Harashima, Shuichi Hoshika, Hiroyuki Kamiya, 2005, FEBS letters.

Opposite-base dependent excision of 5-formyluracil from DNA by hSMUG1

P. Ruoff, A. Matsuda, I. Leiros, 2009, International journal of radiation biology.

Clusterin, an Abundant Serum Factor, Is a Possible Negative Regulator of MT6-MMP/MMP-25 Produced by Neutrophils*

A. Matsuda, Y. Itoh, M. Seiki, 2003, Journal of Biological Chemistry.

Base analog N6-hydroxylaminopurine mutagenesis in Escherichia coli: genetic control and molecular specificity.

T. Kunkel, R. Schaaper, A. Matsuda, 1996, Mutation research.

Conjugation of dipeptide to fluorescent dyes enhances its affinity for a dipeptide transporter (PEPT1) in human intestinal Caco-2 cells.

S. Shuto, A. Matsuda, N. Kamo, 1999, Bioconjugate chemistry.

Rolling circle amplification in a prokaryotic translation system using small circular RNA.

A. Matsuda, Yoshihiro Ito, Y. Sako, 2013, Angewandte Chemie.

Repair of DNA damage in a mitochondrial lysate of Xenopus laevis oocytes.

A. Matsuda, M. Ryoji, H. Katayama, 1996, Nucleic acids research.

Enhancement of the excluded-volume effect in protein extraction using triblock copolymer-based aqueous micellar two-phase systems

A. Matsuda, H. Tani, T. Kamidate, 2001 .

Nucleosides and Nucleotides. 105. DNA Bending in d(A)4 - d(T)4 TRACTS Containing 3-Deazaadenine or 7-Deazaadenine Substituted for Adenine§,1

A. Matsuda, A. Ono, T. Ueda, 1992 .

Total synthesis of syringolin A and improvement of its biological activity.

A. Matsuda, M. Asaka, S. Ichikawa, 2014, Angewandte Chemie.

Function‐Oriented Synthesis of Liponucleoside Antibiotics

A. Matsuda, S. Ichikawa, Tetsuya Tanino, 2014 .

Function-oriented synthesis of simplified caprazamycins: discovery of oxazolidine-containing uridine derivatives as antibacterial agents against drug-resistant bacteria.

A. Matsuda, A. Bouhss, S. Ichikawa, 2010, Journal of medicinal chemistry.

Nucleosides and nucleotides. 114. A convenient method for the synthesis of 3-deazapurine nucleosides from AICA-Riboside

N. Minakawa, A. Matsuda, 1993 .

Synthesis of pacidamycin analogues via an Ugi-multicomponent reaction.

A. Matsuda, M. Sakagami, F. Feng, 2012, Bioorganic & medicinal chemistry letters.

A New Arylsulfate Sulfotransferase Involved in Liponucleoside Antibiotic Biosynthesis in Streptomycetes*

A. Matsuda, B. Gust, Leonard Kaysser, 2010, The Journal of Biological Chemistry.

The synthesis of blocked triplet-phosphoramidites and their use in mutagenesis.

A. Matsuda, D. Santi, A. Ono, 1995, Nucleic acids research.

The immunosuppressive agent mizoribine monophosphate forms a transition state analogue complex with inosine monophosphate dehydrogenase.

G. Petsko, S. Shuto, A. Matsuda, 2003, Biochemistry.

Mutagenicity of (p-nitrophenyl)adenines in Salmonella typhimurium.

Y. Wataya, A. Matsuda, H. Hayatsu, 1991, Mutation research.

Highly Fluorescent 5‐(5,6‐Dimethoxybenzothiazol‐2‐yl)‐2′‐Deoxyuridine 5′‐Triphosphate as an Efficient Substrate for DNA Polymerases

A. Matsuda, Kousuke Sato, A. Sasaki, 2011, Chembiochem : a European journal of chemical biology.

Nucleosides and nucleotides. 112. 2-(1-Hexyn-1-yl)adenosine-5'-uronamides: a new entry of selective A2 adenosine receptor agonists with potent antihypertensive activity.

A. Matsuda, H. Homma, Y. Watanabe, 1992, Journal of medicinal chemistry.

Water mediated Dickerson-Drew-type crystal of DNA dodecamer containing 2'-deoxy-5-formyluridine.

J. Kondo, A. Matsuda, M. Tsunoda, 2002, Biophysical chemistry.

X-Ray analysis of d(CGCGAATTXGCG)(2) containing a 2' or minute-deoxy-N(4)-methoxycytosine residue at X: a characteristic pattern of sugar puckers in the crystalline state of the Dickerson-Drew type DNA dodecamers.

J. Kondo, A. Matsuda, A. Takénaka, 2002, Biophysical chemistry.

Cytotoxic mechanisms of new antitumor nucleoside analogues, 3'-ethynylcytidine (ECyd) and 3'-ethynyluridine (EUrd).

M. Fukushima, Y. Wataya, A. Matsuda, 1997, Nucleic acids symposium series.

Preface

A. Matsuda, P. Herdewijn, M. Egli, 2010 .

Open channel block of NMDA receptors by conformationally restricted analogs of milnacipran and their protective effect against NMDA‐induced neurotoxicity

S. Shuto, A. Matsuda, T. Noguchi, 1999, Synapse.

REVIEW — Current Perspective — (1 S ,2 R )-1-Phenyl-2-[( S )-1-aminopropyl]- N,N -diethylcyclopropane-carboxamide (PPDC), a New Class of NMDA-Receptor Antagonist: Molecular Design by a Novel Conformational Restriction Strategy

S. Shuto, A. Matsuda, K. Yoshii, 2001 .

Palladium-catalyzed cross-coupling of 2-iodoadenosine with terminal alkynes: synthesis and biological activities of 2-alkynyladenosines.

A. Matsuda, T. Miyasaka, H. Machida, 1985, Chemical & pharmaceutical bulletin.

Synthesis of 6-Cyanocytidine and Its Derivatives (Nucleosides and Nucleotides. XX

A. Matsuda, H. Inoue, T. Ueda, 1978 .

PALLADIUM-CATALYZED CROSS-COUPLING OF 2-IODOADENOSINE WITH TERMINAL ALKYNES: SYNTHESIS AND BIOLOGICAL ACTIVITIES OF 2-ALKYNYLADENOSINES

A. Matsuda, T. Miyasaka, H. Machida, 1985 .

NUCLEOSIDES AND NUCLEOTIDES. XX. SYNTHESIS OF 6-CYANOCYTIDINE AND ITS DERIVATIVES

A. Matsuda, H. Inoue, T. Ueda, 1979 .

Metabolism of EICAR (5-ethynyl-1-beta-D-ribofuranosylimidazole-4-carboxamide), a potent inhibitor of inosinate dehydrogenase.

E. De Clercq, A. Matsuda, J. Balzarini, 1997, Advances in experimental medicine and biology.

Synthesis and structure-activity relationships of novel nikkomycin analogs: inhibitors of the fungal cell wall biosynthesis enzyme chitin synthase.

A. Matsuda, K. Iwase, J. Uda, 1999, Nucleic acids symposium series.

Highly beta-selective C-allylation of a ribofuranoside controlling steric hindrance in the transition state.

A. Matsuda, S. Ichikawa, S. Hirano, 2008, Organic letters.

Nucleosides and Nucleotides. 156. Chelation-Controlled and Nonchelation-Controlled Diastereofacial Selective Thiophenol Addition Reactions at the 2‘-Position of 2‘-[(Alkoxycarbonyl)methylene]-2‘-deoxyuridines: Conversion of (Z)-2‘-[(Alkoxycarbonyl)methylene]-2‘-deoxyuridines into Their (E)-Isomers1

S. Shuto, A. Matsuda, Abdalla E A Hassan, 1997 .

Novel hydrolysis-resistant analogues of cyclic ADP-ribose: modification of the "northern" ribose and calcium release activity.

N. Oppenheimer, S. Shuto, A. Matsuda, 2002, Biochemistry.

Mechanism-based design of inosine 5-monophosphate dehydrogenase inhibitors: synthesis and biological activities of 5-ethynyl-1-beta-D-ribofuranosylimidazole-4-carboxamide (EICAR) and its derivatives.

N. Minakawa, A. Matsuda, 1999, Current Medicinal Chemistry.

Chemistry of cyclic ADP-ribose and its analogs.

S. Shuto, A. Matsuda, 2004, Current medicinal chemistry.

Mutagenicity of 5-formylcytosine, an oxidation product of 5-methylcytosine, in DNA in mammalian cells.

A. Matsuda, H. Harashima, H. Kamiya, 2002, Journal of biochemistry.

Synthesis of Pacidamycin Analogues via an Ugi‐Multicomponent Reaction.

A. Matsuda, M. Sakagami, F. Feng, 2012 .

(+/-)-(Z)-2-(aminomethyl)-1-phenylcyclopropanecarboxamide derivatives as a new prototype of NMDA receptor antagonists.

S. Shuto, A. Matsuda, R. Tsujita, 1995, Journal of medicinal chemistry.

Investigations toward the selection of fully-modified 4'-thioRNA aptamers: optimization of in vitro transcription steps in the presence of 4'-thioNTPs.

N. Minakawa, A. Matsuda, Yuka Kato, 2008, Bioorganic & medicinal chemistry.

Synthesis and characterization of oligodeoxynucleotides containing naphthyridine:imidazopyridopyrimidine base pairs at their sticky ends. Application as thermally stabilized decoy molecules.

N. Minakawa, A. Matsuda, Sadao Hikishima, 2007, Chembiochem : a European journal of chemical biology.

Highly efficient enzymatic synthesis of 3'-deoxyapionucleic acid (apioNA) having the four natural nucleobases.

N. Minakawa, A. Matsuda, Kousuke Sato, 2011, Chemical communications.

[Nucleoside kinases and new types of antitumor nucleosides].

A. Matsuda, 1997, Gan to kagaku ryoho. Cancer & chemotherapy.

Amplification of 4'-thioDNA in the presence of 4'-thio-dTTP and 4'-thio-dCTP, and 4'-thioDNA-directed transcription in vitro and in mammalian cells.

N. Minakawa, A. Matsuda, Akiko Kawakami, 2007, Journal of the American Chemical Society.

5-Fluorocytosine in DNA is a mechanism-based inhibitor of HhaI methylase.

A. Matsuda, D. Santi, J. Wu, 1988, Biochemistry.

An intracellular buildup reaction of active siRNA species from short RNA fragments.

S. Shuto, A. Matsuda, Yoshihiro Ito, 2014, Chemical communications.

Unique properties of respiratory chain in Plasmodium falciparum mitochondria.

Hye-Sook Kim, Y. Wataya, A. Matsuda, 2003, Advances in experimental medicine and biology.

Antiviral activities of 5-ethynyl-1-beta-D-ribofuranosylimidazole-4- carboxamide and related compounds

E. De Clercq, N. Minakawa, A. Matsuda, 1991, Antimicrobial Agents and Chemotherapy.

Structure, solubility, and permeability relationships in a diverse middle molecule library.

S. Shuto, A. Matsuda, Takashi Tadokoro, 2021, Bioorganic & medicinal chemistry letters.

Significance of substrate hydrophobicity for recognition by an oligopeptide transporter (PEPT1).

S. Shuto, A. Matsuda, N. Kamo, 2001, Bioconjugate chemistry.

Inhibitory Mechanisms of 1-(3-C-Ethynyl-β-d-ribo-Pentofuranosyl)Uracil (EUrd) on RNA Synthesis

M. Fukushima, Hye-Sook Kim, Y. Wataya, 2005 .

Nucleosides and Nucleotides. Part 43. On the Stereoselectivity of Alkyl Addition Reaction of Pyrimidine 2′-Keto Nucleosides.

A. Matsuda, H. Itoh, T. Ueda, 1991 .