S. Bekker-Jensen

发表

RNF168 Binds and Amplifies Ubiquitin Conjugates on Damaged Chromosomes to Allow Accumulation of Repair Proteins

J. Ellenberg, R. Pepperkok, D. Durocher, 2009, Cell.

RNF8 Ubiquitylates Histones at DNA Double-Strand Breaks and Promotes Assembly of Repair Proteins

Jiri Bartek, Helene Faustrup, Fredrik Melander, 2007, Cell.

Spatial organization of the mammalian genome surveillance machinery in response to DNA strand breaks

Jiri Bartek, Risa Kitagawa, Fredrik Melander, 2006, The Journal of cell biology.

DVC1 (C1orf124) is a DNA damage–targeting p97 adaptor that promotes ubiquitin-dependent responses to replication blocks

S. V. Nielsen, R. Hartmann-Petersen, N. Mailand, 2012, Nature Structural &Molecular Biology.

Mass Spectrometric Analysis of Lysine Ubiquitylation Reveals Promiscuity at Site Level*

L. Jensen, H. Horn, N. Mailand, 2010, Molecular & Cellular Proteomics.

Regulation of PCNA–protein interactions for genome stability

N. Mailand, S. Bekker-Jensen, Ian Gibbs-Seymour, 2013, Nature Reviews Molecular Cell Biology.

Regulation of DNA double-strand break repair by ubiquitin and ubiquitin-like modifiers

N. Mailand, S. Bekker-Jensen, Simon Bekker-Jensen, 2016, Nature Reviews Molecular Cell Biology.

Proteomics reveals dynamic assembly of repair complexes during bypass of DNA cross-links

Jürgen Cox, Matthias Mann, Kay Hofmann, 2015, Science.

Destruction of Claspin by SCFbetaTrCP restrains Chk1 activation and facilitates recovery from genotoxic stress.

Jiri Bartek, N. Mailand, S. Bekker-Jensen, 2006, Molecular cell.

GIGYF1/2-Driven Cooperation between ZNF598 and TTP in Posttranscriptional Regulation of Inflammatory Signaling.

J. Olsen, N. Mailand, S. Bekker-Jensen, 2019, Cell reports.

TRIP12 and UBR5 Suppress Spreading of Chromatin Ubiquitylation at Damaged Chromosomes

Jiri Bartek, Darren Saunders, Beate Neumann, 2014, Cell.

Alternative Translation Initiation Generates a Functionally Distinct Isoform of the Stress-Activated Protein Kinase MK2.

Dorte B. Bekker-Jensen, Manuel D. Díaz-Muñoz, J. Olsen, 2019, Cell reports.

Alternative translation initiation generates a functionally distinct isoform of the stress-activated kinase MK2

Dorte B. Bekker-Jensen, Manuel D. Díaz-Muñoz, J. Olsen, 2018, bioRxiv.

p38-MK2 signaling axis regulates RNA metabolism after UV-light-induced DNA damage

Sebastian A. Wagner, N. Mailand, S. Bekker-Jensen, 2018, Nature Communications.

The Role of TTP Phosphorylation in the Regulation of Inflammatory Cytokine Production by MK2/3

J. Olsen, S. Bekker-Jensen, M. Gaestel, 2019, The Journal of Immunology.

Mislocalization of the MRN complex prevents ATR signaling during adenovirus infection

C. Lilley, M. Weitzman, S. Bekker-Jensen, 2009, The EMBO journal.

Mass Spectrometric Analysis of Lysine Ubiquitylation Reveals Promiscuity at Site Level* □ S

L. Jensen, H. Horn, N. Mailand, 2011 .

The ubiquitin ligase XIAP recruits LUBAC for NOD2 signaling in inflammation and innate immunity.

A. Strasser, N. Mailand, S. Bekker-Jensen, 2012, Molecular cell.

Ribosome impairment regulates intestinal stem cell identity via ZAKɑ activation

W. Zwart, S. Bekker-Jensen, R. A. van der Kammen, 2022, Nature Communications.

Nucleotide excision repair–induced H2A ubiquitination is dependent on MDC1 and RNF8 and reveals a universal DNA damage response

N. Mailand, S. Bekker-Jensen, J. Lukas, 2009, The Journal of cell biology.

Meeting Report: Aging Research and Drug Discovery

L. Ferrucci, B. Kennedy, L. Partridge, 2022, Aging.

ZAKβ is activated by cellular compression and mediates contraction‐induced MAP kinase signaling in skeletal muscle

Dorte B. Bekker-Jensen, Ana Martinez del Val, Xiang Li, 2022, The EMBO journal.

RNF138 joins the HR team

N. Mailand, S. Bekker-Jensen, Simon Bekker-Jensen, 2015, Nature Cell Biology.

Ubiquitin and the DNA damage response

N. Mailand, S. Bekker-Jensen, Simon Bekker-Jensen, 2012, Cell cycle.

Ribosome stalling is a signal for metabolic regulation by the ribotoxic stress response

S. Bekker-Jensen, S. Poulsen, D. Gatfield, 2022, Cell metabolism.

ATR Prohibits Replication Catastrophe by Preventing Global Exhaustion of RPA

N. Mailand, S. Bekker-Jensen, D. H. Larsen, 2013, Cell.

Polyol synthesis in Aspergillus niger: Influence of oxygen availability, carbon and nitrogen sources on the metabolism

S. Bekker-Jensen, J. Nielsen, J. Dynesen, 2006, Biotechnology and bioengineering.

ICLs: a chicken without an egg

N. Mailand, S. Bekker-Jensen, 2012, Nature Reviews Molecular Cell Biology.

Structural Analysis of a Complex between Small Ubiquitin-like Modifier 1 (SUMO1) and the ZZ Domain of CREB-binding Protein (CBP/p300) Reveals a New Interaction Surface on SUMO*

N. Mailand, S. Bekker-Jensen, M. Akke, 2016, The Journal of Biological Chemistry.

Chromatin relaxation in response to DNA double-strand breaks is modulated by a novel ATM- and KAP-1 dependent pathway

Y. Shiloh, S. Bekker-Jensen, J. Bartek, 2006, Nature Cell Biology.

OTULIN restricts Met1-linked ubiquitination to control innate immune signaling.

Sebastian A. Wagner, N. Mailand, S. Bekker-Jensen, 2013, Molecular cell.

Mdc1 couples DNA double‐strand break recognition by Nbs1 with its H2AX‐dependent chromatin retention

Jiri Bartek, Michal Goldberg, Fredrik Melander, 2004, The EMBO journal.

A new cellular stress response that triggers centriolar satellite reorganization and ciliogenesis

N. Mailand, S. Bekker-Jensen, Chunaram Choudhary, 2013, The EMBO journal.

Histone H1 couples initiation and amplification of ubiquitin signalling after DNA damage

Chunaram Choudhary, T. Sixma, N. Mailand, 2015, Nature.

H4 K20me0 marks post-replicative chromatin and recruits the TONSL-MMS22L DNA repair complex

Axel Imhof, Hongda Huang, Anja Groth, 2016, Nature.

SCAI promotes DNA double-strand break repair in distinct chromosomal contexts

M. Mann, N. Mailand, S. Bekker-Jensen, 2016, Nature Cell Biology.

ATR Prohibits Replication Catastrophe by Preventing Global Exhaustion of RPA

N. Mailand, S. Bekker-Jensen, D. H. Larsen, 2013, Cell.

TRIP12 and UBR5 Suppress Spreading of Chromatin Ubiquitylation at Damaged Chromosomes

B. Neumann, J. Hériché, N. Mailand, 2012, Cell.

A new non‐catalytic role for ubiquitin ligase RNF8 in unfolding higher‐order chromatin structure

N. Mailand, S. Bekker-Jensen, D. H. Larsen, 2012, The EMBO journal.

Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass

Sebastian A. Wagner, N. Mailand, S. Bekker-Jensen, 2012, Nature Cell Biology.

Universitet p 38-MK 2 signaling axis regulates RNA metabolism after UV-light-induced DNA damage

Sebastian A. Wagner, N. Mailand, S. Bekker-Jensen, 2018 .

Ribosomal stress-surveillance: three pathways is a magic number

S. Bekker-Jensen, A. Vind, Aitana Victoria Genzor, 2020, Nucleic acids research.

ATR Prohibits Replication Catastrophe by Preventing Global Exhaustion of RPA

N. Mailand, S. Bekker-Jensen, D. H. Larsen, 2013, Cell.

UBL5 is essential for pre‐mRNA splicing and sister chromatid cohesion in human cells

J. Waage, N. Mailand, S. Bekker-Jensen, 2014, EMBO reports.

HERC2 coordinates ubiquitin-dependent assembly of DNA repair factors on damaged chromosomes

N. Mailand, S. Bekker-Jensen, J. Bartek, 2010, Nature Cell Biology.

Assembly and function of DNA double-strand break repair foci in mammalian cells.

N. Mailand, S. Bekker-Jensen, Simon Bekker-Jensen, 2010, DNA repair.

Dynamic assembly and sustained retention of 53BP1 at the sites of DNA damage are controlled by Mdc1/NFBD1

S. Bekker-Jensen, J. Bartek, J. Lukas, 2005, The Journal of cell biology.

53BP1 nuclear bodies form around DNA lesions generated by mitotic transmission of chromosomes under replication stress

B. Neumann, C. Doil, S. Bekker-Jensen, 2011, Nature Cell Biology.

Run, Ribosome, Run: From compromised translation to human health.

S. Bekker-Jensen, Melanie Blasius, A. Vind, 2023, Antioxidants & redox signaling.

Phosphorylation of SDT repeats in the MDC1 N terminus triggers retention of NBS1 at the DNA damage–modified chromatin

N. Mailand, S. Bekker-Jensen, J. Bartek, 2008, The Journal of cell biology.

Proteome-wide analysis of SUMO2 targets in response to pathological DNA replication stress in human cells.

Sebastian A. Wagner, Y. Liu, N. Mailand, 2015, DNA repair.

DNA damage–inducible SUMOylation of HERC2 promotes RNF8 binding via a novel SUMO-binding Zinc finger

N. Mailand, S. Bekker-Jensen, J. Nilsson, 2012, The Journal of cell biology.

Human RNF169 is a negative regulator of the ubiquitin-dependent response to DNA double-strand breaks

N. Mailand, S. Bekker-Jensen, J. Lukas, 2012, The Journal of cell biology.

The ubiquitin‐ and SUMO‐dependent signaling response to DNA double‐strand breaks

N. Mailand, S. Bekker-Jensen, Simon Bekker-Jensen, 2011, FEBS letters.

Human RNF 169 is a negative regulator of the ubiquitin-dependent response to DNA double-strand breaks

N. Mailand, S. Bekker-Jensen, J. Lukas, 2022 .

Activation of the ATR kinase by the RPA-binding protein ETAA1

M. Mann, N. Mailand, S. Bekker-Jensen, 2016, Nature Cell Biology.

Regulation of the Golgi Apparatus by p38 and JNK Kinases during Cellular Stress Responses

Dorte B. Bekker-Jensen, J. Olsen, S. Bekker-Jensen, 2021, International journal of molecular sciences.

Renal-retinal ciliopathy gene Sdccag8 regulates DNA damage response signaling.

S. Bekker-Jensen, T. Hurd, A. Kispert, 2014, Journal of the American Society of Nephrology : JASN.

Disease-causing mutations in the XIAP BIR2 domain impair NOD2-dependent immune signalling

N. Mailand, S. Bekker-Jensen, S. Ehl, 2013, EMBO molecular medicine.

ZAKα Recognizes Stalled Ribosomes through Partially Redundant Sensor Domains.

Dorte B. Bekker-Jensen, J. Olsen, S. Bekker-Jensen, 2020, Molecular cell.

Lamin A/C-dependent interaction with 53BP1 promotes cellular responses to DNA damage

N. Mailand, S. Bekker-Jensen, Ian Gibbs-Seymour, 2015, Aging cell.

Protein Aggregation Capture on Microparticles Enables Multipurpose Proteomics Sample Preparation*

Tanveer S. Batth, Jesper V. Olsen, J. Olsen, 2019, Molecular & Cellular Proteomics.

Ubiquitin-SUMO Circuitry Controls Activated Fanconi Anemia ID Complex Dosage in Response to DNA Damage

Chunaram Choudhary, Lori A. Passmore, Jesper V. Olsen, 2015, Molecular cell.

RNF111/Arkadia is a SUMO-targeted ubiquitin ligase that facilitates the DNA damage response

Sebastian A. Wagner, N. Mailand, S. Bekker-Jensen, 2013, The Journal of cell biology.

The Deubiquitylating Enzyme USP44 Counteracts the DNA Double-strand Break Response Mediated by the RNF8 and RNF168 Ubiquitin Ligases*

N. Mailand, S. Bekker-Jensen, C. Lukas, 2013, Journal of Biological Chemistry.

RNF8 and RNF168 but not HERC2 are required for DNA damage-induced ubiquitylation in chicken DT40 cells.

N. Mailand, S. Bekker-Jensen, A. Alpi, 2012, DNA repair.

RNF 111 / Arkadia is a SUMO-targeted ubiquitin ligase that facilitates the DNA damage response

Sebastian A. Wagner, N. Mailand, S. Bekker-Jensen, 2022 .

Claspin Operates Downstream of TopBP1 To Direct ATR Signaling towards Chk1 Activation

N. Mailand, S. Bekker-Jensen, J. Bartek, 2006, Molecular and Cellular Biology.

Histone Displacement during Nucleotide Excision Repair

S. Bekker-Jensen, J. Bartek, C. Dinant, 2012, International journal of molecular sciences.

USP7 counteracts SCFβTrCP- but not APCCdh1-mediated proteolysis of Claspin

N. Mailand, S. Bekker-Jensen, J. Bartek, 2009, The Journal of cell biology.

Selective autophagy maintains centrosome integrity and accurate mitosis by turnover of centriolar satellites

Lea M. Harder, E. Papaleo, S. Bekker-Jensen, 2018, Nature Communications.

p38- and MK2-dependent signalling promotes stress-induced centriolar satellite remodelling via 14-3-3-dependent sequestration of CEP131/AZI1

Sebastian A. Wagner, N. Mailand, S. Bekker-Jensen, 2015, Nature Communications.

PRMT5-mediated regulatory arginine methylation of RIPK3

Ana Martinez del Val, J. Olsen, S. Bekker-Jensen, 2022, bioRxiv.

SDCCAG8 Interacts with RAB Effector Proteins RABEP2 and ERC1 and Is Required for Hedgehog Signaling

S. Bekker-Jensen, T. Hurd, J. Andersen, 2016, PloS one.

Osmotic Stress Blocks Mobility and Dynamic Regulation of Centriolar Satellites

S. Bekker-Jensen, M. A. Tollenaere, Julie C Nielsen, 2018, Cells.

Human Xip1 (C2orf13) Is a Novel Regulator of Cellular Responses to DNA Strand Breaks*

N. Mailand, S. Bekker-Jensen, J. Bartek, 2007, Journal of Biological Chemistry.

Spatial-proteomics reveals phospho-signaling dynamics at subcellular resolution

Dorte B. Bekker-Jensen, F. Lund-Johansen, J. Olsen, 2021, Nature Communications.

Ubiquitin‐like protein UBL5 promotes the functional integrity of the Fanconi anemia pathway

N. Mailand, S. Bekker-Jensen, Yasuyoshi Oka, 2015, The EMBO journal.

TRAIP is a PCNA-binding ubiquitin ligase that protects genome stability after replication stress

M. Mann, N. Mailand, S. Bekker-Jensen, 2016, The Journal of cell biology.

Centriolar satellites: key mediators of centrosome functions

N. Mailand, S. Bekker-Jensen, M. Tollenaere, 2014, Cellular and Molecular Life Sciences.

Spatial-proteomics reveal in-vivo phospho-signaling dynamics at subcellular resolution

Dorte B. Bekker-Jensen, F. Lund-Johansen, J. Olsen, 2021, bioRxiv.

Histone H1 couples initiation and amplification of ubiquitin signalling after DNA damage

T. Sixma, N. Mailand, S. Bekker-Jensen, 2015, Nature.

p38-MK2 signaling axis regulates RNA metabolism after UV-light-induced DNA damage

Sebastian A. Wagner, N. Mailand, S. Bekker-Jensen, 2018, Nature Communications.

Mechanistic basis for nigericin-induced NLRP1 inflammasome activation in human epithelial cells

S. Bekker-Jensen, F. Zhong, E. Meunier, 2023, bioRxiv.

HERC2 coordinates ubiquitin-dependent assembly of DNA repair factors on damaged chromosomes

N. Mailand, S. Bekker-Jensen, J. Bartek, 2010, Nature Cell Biology.

Centriolar satellites: key mediators of centrosome functions

N. Mailand, S. Bekker-Jensen, M. Tollenaere, 2014, Cellular and Molecular Life Sciences.