N. Borgese

发表

Formation of stacked ER cisternae by low affinity protein interactions

J. Lippincott-Schwartz, E. Snapp, R. Hegde, 2003, The Journal of cell biology.

KDEL and KKXX retrieval signals appended to the same reporter protein determine different trafficking between endoplasmic reticulum, intermediate compartment, and Golgi complex.

N. Borgese, M. Stornaiuolo, M. Torrisi, 2003, Molecular biology of the cell.

Autophagy and Neurodegeneration: Insights from a Cultured Cell Model of ALS

N. Borgese, F. Navone, P. Genevini, 2015, Cells.

Amyotrophic Lateral Sclerosis-Linked Mutant VAPB Inclusions Do Not Interfere with Protein Degradation Pathways or Intracellular Transport in a Cultured Cell Model

N. Borgese, L. Cantoni, F. Navone, 2014, PloS one.

Membrane interactions in secretory cell systems.

P. De Camilli, J. Meldolesi, N. Borgese, 1979, Symposia of the Society for Experimental Biology.

Selective activation of the transcription factor ATF6 mediates endoplasmic reticulum proliferation triggered by a membrane protein

N. Borgese, C. Verderio, S. Bulotta, 2011, Proceedings of the National Academy of Sciences.

NADH‐cytochrome b 5 reductase and cytochrome b 5 isoforms as models for the study of post‐translational targeting to the endoplasmic reticulum

N. Borgese, G. Pietrini, A. D’Arrigo, 1993, FEBS letters.

A novel point mutation in a 3' splice site of the NADH-cytochrome b5 reductase gene results in immunologically undetectable enzyme and impaired NADH-dependent ascorbate regeneration in cultured fibroblasts of a patient with type II hereditary methemoglobinemia.

N. Borgese, G. Uziel, M. Landi, 1995, American journal of human genetics.

A mutant cytochrome b 5 with a lengthened membrane anchor escapes from the endoplasmic reticulum and reaches the plasma membrane ( brefeldin A / mammalian cells / protein sorting / retention mechanisms / tail-anchored proteins )

Antonello, E. Pedrazzini, N. Borgese, 2005 .

Chronic Deficiency of Nitric Oxide Affects Hypoxia Inducible Factor-1α (HIF-1α) Stability and Migration in Human Endothelial Cells

N. Borgese, M. Cattaneo, E. Nisoli, 2011, PloS one.

Two tail-anchored protein variants, differing in transmembrane domain length and intracellular sorting, interact differently with lipids.

M. Masserini, M. Francolini, S. Colombo, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Activation of endothelial nitric-oxide synthase by tumor necrosis factor-alpha: a novel pathway involving sequential activation of neutral sphingomyelinase, phosphatidylinositol-3' kinase, and Akt.

E. Clementi, N. Borgese, S. Moncada, 2003, Molecular pharmacology.

Three translationally regulated mRNAs are stored in the cytoplasm of clam oocytes.

N. Borgese, J. Ruderman, K. Swenson, 1987, Developmental biology.

Interactions between nitric oxide and sphingolipids and the potential consequences in physiology and pathology.

E. Clementi, J. Meldolesi, N. Borgese, 2003, Trends in pharmacological sciences.

Immunological similarity of the NADH—cytochrome c electron transport system in microsomes, Golgi complex and mitochondrial outer membrane of rat liver cells

J. Meldolesi, N. Borgese, 1976, FEBS letters.

Cell culture models to investigate the selective vulnerability of motoneuronal mitochondria to familial ALS‐linked G93ASOD1

M. Francolini, N. Borgese, A. Mangolini, 2006, The European journal of neuroscience.

Transmembrane topogenesis of a tail‐anchored protein is modulated by membrane lipid composition

R. Hegde, N. Borgese, M. Makarow, 2005, The EMBO journal.

The tale of tail-anchored proteins

S. Colombo, E. Pedrazzini, N. Borgese, 2003, The Journal of cell biology.

Translocation of the C Terminus of a Tail-anchored Protein across the Endoplasmic Reticulum Membrane in Yeast Mutants Defective in Signal Peptide-driven Translocation*

E. Pedrazzini, N. Borgese, M. Makarow, 2003, The Journal of Biological Chemistry.

Discrimination between the endoplasmic reticulum and mitochondria by spontaneously inserting tail‐anchored proteins

S. Colombo, N. Borgese, Bruna Figueiredo Costa, 2018, Traffic.

CAML mediates survival of Myc-induced lymphoma cells independent of tail-anchored protein insertion

N. Borgese, R. Bram, Lonn D. Lindquist, 2017, Cell Death Discovery.

The role of cytosolic proteins in the insertion of tail-anchored proteins into phospholipid bilayers

S. Colombo, N. Borgese, R. Longhi, 2009, Journal of Cell Science.

How tails guide tail-anchored proteins to their destinations.

S. Colombo, N. Borgese, S. Brambillasca, 2007, Current opinion in cell biology.

ACTIVATION OF THE ENDOTHELIAL NITRIC OXIDE SYNTHASE BY TUMOUR NECROSIS FACTOR- a : A NOVEL FEED-BACK MECHANISM REGULATING CELL DEATH

E. Clementi, N. Borgese, R. Barsacchi, 2000 .

NADH-cytochrome b5 reductase and cytochrome b5. The problem of posttranslational targeting to the endoplasmic reticulum.

N. Borgese, G. Pietrini, A. D’Arrigo, 1993, Sub-cellular biochemistry.

Localization and Biosynthesis of NADH-Cytochrome b(5) reductase, an integral membrane protein, in rat liver cells. III. Evidence for the independent insertion and turnover of the enzyme in various subcellular compartments

J. Meldolesi, N. Borgese, G. Pietrini, 1980, The Journal of cell biology.

Localization and biosynthesis of NADH-cytochrome b5 reductase, an integral membrane protein, in rat liver cells. I. Distribution of the enzyme activity in microsomes, mitochondria, and golgi complex

J. Meldolesi, N. Borgese, Jacopo Meldolesi, 1980, The Journal of cell biology.

Site of synthesis of rat liver NADH—cytochrome b 5 reductase, an integral membrane protein

N. Borgese, Gaetani Sancia, 1980, FEBS letters.

Membrane synthesis and turnover in secretory cell systems.

J. Meldolesi, N. Borgese, 1981, Methods in cell biology.

The inhibitory effect of methylenedisalicylic acid on the attachment of ribosomes to microsomal membranes in vitro

N. Borgese, D. Macconi, G. Aporti, 1980, FEBS letters.

Two transcripts encode rat cytochrome b 5 reductase ( cDNA / erythrocytes / liver / membrane proteins / RNase A mapping )

N. Borgese, G. Pietrini, P. Carrera, 2022 .

An investigation of the effect of membrane curvature on transmembrane-domain dependent protein sorting in lipid bilayers

N. Borgese, B. Goud, M. Fossati, 2014, Cellular logistics.

A role for N-myristoylation in protein targeting: NADH-cytochrome b5 reductase requires myristic acid for association with outer mitochondrial but not ER membranes

N. Borgese, G. Pietrini, D. Aggujaro, 1996, The Journal of cell biology.

The effects of Bothrops jararacussu venom and its components on frog nerve-muscle preparation

N. Borgese, L. Rodrigues-Simioni, B. Ceccarelli, 1983, Neuroscience.

Distribution of the integral membrane protein NADH-cytochrome b5 reductase in rat liver cells, studied with a quantitative radioimmunoblotting assay.

N. Borgese, G. Pietrini, 1986, The Biochemical journal.

Studies on the intracellular distribution of Sindbis messenger RNA in infected chick-embryo fibroblasts. 1. Presence of extrapolyribosomal 26-S RNA in the membrane fraction.

J. Meldolesi, R. Cancedda, N. Borgese, 1980, European journal of biochemistry.

Studies on the intracellular distribution of Sindbis messenger RNA in infected chick embryo fibroblasts. 2. Non-parallel distribution of 26-S RNA and ribosomes within microsomal subfractions.

J. Meldolesi, R. Cancedda, N. Borgese, 1980, European journal of biochemistry.

ERO1 alpha deficiency impairs angiogenesis by increasing N-glycosylation of a proangiogenic VEGFA

N. Borgese, M. Lenardo, S. Fumagalli, 2022, Redox biology.

The induction of neoplasms with a substance released from mouse tumors by tissue culture.

N. Borgese, G. E. Grubbs, B. Eddy, 1957, Virology.

A Novel Point Mutation in a 3' Splice Site of the NADH-Cytochrome b5 Reductase Gene Results in Immunologically Undetectable Enzyme and Impaired NADH-Dependent Ascorbate Regeneration in Cultured Fibroblasts of a Patient with Type 11 Hereditary Methemoglobinemia

N. Borgese, G. Uziel, M. Landi, 2007 .

Immunologically undetectable human placental lactogen in a normal pregnancy.

N. Borgese, U. Nicolini, M. Sideri, 1983, British journal of obstetrics and gynaecology.

The specific subcellular localization of two isoforms of cytochrome b5 suggests novel targeting pathways.

N. Borgese, R. Longhi, A. D’Arrigo, 1993, The Journal of biological chemistry.

Both the outer mitochondrial membrane and the microsomal forms of cytochrome b5 reductase contain covalently bound myristic acid. Quantitative analysis on the polyvinylidene difluoride-immobilized proteins.

N. Borgese, R. Longhi, 1990, The Biochemical journal.

Two transcripts encode rat cytochrome b5 reductase.

N. Borgese, G. Pietrini, P. Carrera, 1988, Proceedings of the National Academy of Sciences of the United States of America.

In vitro synthesis and post‐translational insertion into microsomes of the integral membrane protein, NADH‐cytochrome b5 oxidoreductase.

N. Borgese, S. Gaetani, 1983, The EMBO journal.

Rat erythrocyte NADH-cytochrome b5 reductase. Quantitation and comparison between the membrane-bound and soluble forms using an antibody against the rat liver enzyme.

N. Borgese, G. Pietrini, L. Parola, 1982, The Journal of biological chemistry.

Localization and biosynthesis of NADH-cytochrome b5 reductase, an integral membrane protein, in rat liver cells. II. Evidence that a single enzyme accounts for the activity in its various subcellular locations

J. Meldolesi, N. Borgese, G. Pietrini, 1980, The Journal of cell biology.

The GET pathway can increase the risk of mitochondrial outer membrane proteins to be mistargeted to the ER

M. Schuldiner, N. Borgese, B. Schwappach, 2018, Journal of Cell Science.

Trafficking of tail-anchored proteins: transport from the endoplasmic reticulum to the plasma membrane and sorting between surface domains in polarised epithelial cells.

E. Pedrazzini, N. Borgese, A. Bulbarelli, 2002, Journal of cell science.

Endoplasmic Reticulum

N. Borgese, 1993, Subcellular Biochemistry.

Neoplasms in mice inoculated with a tumor agent carried in tissue culture.

N. Borgese, S E STEWART, B E EDDY, 1958, Journal of the National Cancer Institute.

Dynamic and reversible restructuring of the ER induced by PDMP in cultured cells

M. Francolini, N. Borgese, P. Ronchi, 2006, Journal of Cell Science.

Purification and characterization of two plasma membrane domains from ejaculated bull spermatozoa

N. Borgese, G. Fumagalli, I. de Curtis, 1986, The Journal of cell biology.

Targeting of a tail-anchored protein to endoplasmic reticulum and mitochondrial outer membrane by independent but competing pathways.

S. Colombo, E. Pedrazzini, N. Borgese, 2001, Molecular biology of the cell.

Mutant VAPB: Culprit or Innocent Bystander of Amyotrophic Lateral Sclerosis?

N. Borgese, N. Nukina, F. Navone, 2021, Contact (Thousand Oaks (Ventura County, Calif.)).

The Link between VAPB Loss of Function and Amyotrophic Lateral Sclerosis

S. Colombo, N. Borgese, F. Navone, 2021, Cells.

Transmembrane domain–dependent partitioning of membrane proteins within the endoplasmic reticulum

M. Francolini, S. Colombo, N. Borgese, 2008, The Journal of cell biology.

A single mRNA, transcribed from an alternative, erythroid-specific, promoter, codes for two non-myristylated forms of NADH-cytochrome b5 reductase

N. Borgese, G. Pietrini, A. Vitale, 1992, The Journal of cell biology.

Activation of the Endothelial Nitric-oxide Synthase by Tumor Necrosis Factor-α

E. Clementi, N. Borgese, R. Barsacchi, 2001, The Journal of Biological Chemistry.

An erythroid-specific transcript generates the soluble form of NADH-cytochrome b5 reductase in humans.

N. Borgese, M. Cappellini, A. Bulbarelli, 1998, Blood.

Visualization of endoplasmic reticulum subdomains in cultured cells.

M. Francolini, S. Colombo, N. Borgese, 2014, Journal of visualized experiments : JoVE.

Ribosomal-membrane interaction: in vitro binding of ribosomes to microsomal membranes.

N. Borgese, G. Kreibich, D. Sabatini, 1974, Journal of molecular biology.

Targeting pathways of C-tail-anchored proteins.

N. Borgese, Elisa Fasana, 2011, Biochimica et biophysica acta.

Membrane Insertion of Tail-anchored Proteins

N. Borgese, 2015 .

Endoplasmic reticulum architecture: structures in flux.

E. Snapp, M. Francolini, N. Borgese, 2006, Current opinion in cell biology.

Getting membrane proteins on and off the shuttle bus between the endoplasmic reticulum and the Golgi complex

N. Borgese, 2016, Journal of Cell Science.

Congenital methemoglobinemia due to methemoglobin reductase deficiency in two unrelated American black families.

N. Borgese, J. Prchal, M. Moore, 1990, The American journal of medicine.

Selenoprotein N is an endoplasmic reticulum calcium sensor that links luminal calcium levels to a redox activity

S. Colombo, N. Borgese, M. Salmona, 2020, Proceedings of the National Academy of Sciences.

Enzymatic instability of NADH-cytochrome b5 reductase as a cause of hereditary methemoglobinemia type I (red cell type).

N. Borgese, K. Shirabe, D. Hultquist, 1992, The Journal of biological chemistry.

The Ways of Tails: the GET Pathway and more

S. Colombo, N. Borgese, B. Schwappach, 2019, The Protein Journal.

Tail-anchored protein insertion in mammals. FUNCTION AND RECIPROCAL INTERACTIONS OF THE TWO SUBUNITS OF THE TRC40 RECEPTOR.

S. Colombo, N. Borgese, R. Bram, 2016, The Journal of Biological Chemistry.

PI(4,5)P2-Dependent and Ca2+-Regulated ER-PM Interactions Mediated by the Extended Synaptotagmins

S. Colombo, N. Borgese, P. Camilli, 2013, Cell.

Endothelial nitric oxide synthase is segregated from caveolin-1 and localizes to the leading edge of migrating cells.

E. Clementi, N. Borgese, R. Barsacchi, 2006, Experimental cell research.

The fifth subunit in α3β4 nicotinic receptor is more than an accessory subunit

S. Colombo, N. Borgese, M. Sciaccaluga, 2018, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

A cellular system to study the role of nitric oxide in cell death, survival, and migration.

E. Clementi, N. Borgese, C. Perrotta, 2005, Neurotoxicology.

Basal nitric oxide release attenuates cell migration of HeLa and endothelial cells.

N. Borgese, M. Cattaneo, L. Vicentini, 2009, Biochemical and biophysical research communications.

A positive signal prevents secretory membrane cargo from recycling between the Golgi and the ER

S. Colombo, N. Borgese, M. Fossati, 2014, The EMBO journal.

Mechanism of Residence of Cytochrome B(5), a Tail-Anchored Protein, in the Endoplasmic Reticulum

E. Pedrazzini, N. Borgese, A. Villa, 2000, The Journal of cell biology.

Nicotine-Modulated Subunit Stoichiometry Affects Stability and Trafficking of α3β4 Nicotinic Receptor

S. Colombo, N. Borgese, C. Gotti, 2013, The Journal of Neuroscience.

A mutant cytochrome b5 with a lengthened membrane anchor escapes from the endoplasmic reticulum and reaches the plasma membrane.

E. Pedrazzini, N. Borgese, A. Villa, 1996, Proceedings of the National Academy of Sciences of the United States of America.

CDK5 Regulatory Subunit-associated Protein 1-Like 1 (CDKAL1) Is a Tail-anchored Protein in the Endoplasmic Reticulum (ER) of Insulinoma Cells*

S. Colombo, N. Borgese, M. Solimena, 2012, The Journal of Biological Chemistry.

Uncovering common principles in protein export of malaria parasites.

H. Stunnenberg, T. Gilberger, S. Colombo, 2012, Cell host & microbe.

Remote Origins of Tail‐Anchored Proteins

N. Borgese, M. Righi, 2010, Traffic.

N-myristoylation determines dual targeting of mammalian NADH-cytochrome b(5) reductase to ER and mitochondrial outer membranes by a mechanism of kinetic partitioning

S. Colombo, N. Borgese, R. Longhi, 2005, The Journal of cell biology.

Concentration of NADH-cytochrome b5 reductase in erythrocytes of normal and methemoglobinemic individuals measured with a quantitative radioimmunoblotting assay.

N. Borgese, G. Pietrini, S. Gaetani, 1987, The Journal of clinical investigation.

Unassisted translocation of large polypeptide domains across phospholipid bilayers

N. Borgese, M. Makarow, M. Yabal, 2006, The Journal of cell biology.

Biogenesis of tail-anchored proteins.

N. Borgese, M. Makarow, M. Yabal, 2003, Biochemical Society transactions.

Restructured endoplasmic reticulum generated by mutant amyotrophic lateral sclerosis-linked VAPB is cleared by the proteasome

M. Francolini, N. Borgese, G. Bertoni, 2012, Journal of Cell Science.

VAPB depletion alters neuritogenesis and phosphoinositide balance in motoneuron-like cells: relevance to VAPB-linked amyotrophic lateral sclerosis

M. N. Colombo, S. Colombo, N. Borgese, 2019, Journal of Cell Science.

A VAPB mutant linked to amyotrophic lateral sclerosis generates a novel form of organized smooth endoplasmic reticulum

C. Hoogenraad, M. Francolini, N. Borgese, 2010, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Tail-anchored Protein Insertion in Mammals

S. Colombo, N. Borgese, A. Crespi, 2016, The Journal of Biological Chemistry.

The WRB Subunit of the Get3 Receptor is Required for the Correct Integration of its Partner CAML into the ER

S. Colombo, N. Borgese, H. J. F. Carvalho, 2019, Scientific Reports.

The targeting information of the mitochondrial outer membrane isoform of cytochrome b5 is contained within the carboxyl‐terminal region

N. Borgese, A. D’Arrigo, Antonello D'Arrigo, 1995, FEBS letters.

Correction for Ceppi et al., Two tail-anchored protein variants, differing in transmembrane domain length and intracellular sorting, interact differently with lipids

M. Masserini, M. Francolini, S. Colombo, 2005, Proceedings of the National Academy of Sciences.

Cubic membranes : a legend beyond the Flatland * of cell membrane organization

N. Borgese, S. Kohlwein, Yuru Deng, 2022 .

Unassisted translocation of large polypeptide domains across phospholipid bilayers

N. Borgese, M. Makarow, M. Yabal, 2006, The Journal of cell biology.

Searching for remote homologs of CAML among eukaryotes

N. Borgese, 2020, Traffic.