H. Omran

H. Omran, G. Caridi, F. Hildebrandt, 1999, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

Phosphorylation by casein kinase 2 induces PACS‐1 binding of nephrocystin and targeting to cilia

H. Zentgraf, H. Omran, B. Schermer, 2005, The EMBO journal.

Further evidence for a somatic KRAS mutation in a pilocytic astrocytoma.

C. Weiller, S. Pfister, H. Omran, 2007, Neuropediatrics.

Functional characterization of a BRAF insertion mutant associated with pilocytic astrocytoma

S. Pfister, H. Omran, H. Witt, 2011, International journal of cancer.

Target discovery screens using pooled shRNA libraries and next-generation sequencing: A model workflow and analytical algorithm

Christiane Schaefer, Eberhard Korsching, Nikhil Mallela, 2018, PloS one.

Congenital Heart Disease and Other Heterotaxic Defects in a Large Cohort of Patients With Primary Ciliary Dyskinesia

H. Omran, P. Molina, P. Noone, 2007, Circulation.

High-throughput mutation analysis in patients with a nephronophthisis-associated ciliopathy applying multiplexed barcoded array-based PCR amplification and next-generation sequencing

H. Omran, Susan J Allen, R. Lyons, 2012, Journal of Medical Genetics.

Consensus nomenclature for dyneins and associated assembly factors

H. Omran, E. Bruford, G. Pazour, 2022, The Journal of cell biology.

Tyrosine kinase 2 is not limiting human antiviral type III interferon responses

H. Omran, S. Ehl, S. Fuchs, 2016, European journal of immunology.

A bumpy road to the diagnosis of a Kytococcus schroeteri shunt infection.

H. Omran, A. Brentrup, K. Becker, 2013, Journal of medical microbiology.

NPHP proteins: gatekeepers of the ciliary compartment

H. Omran, 2010, The Journal of cell biology.

Motile ciliopathies

H. Omran, M. Zariwala, J. Wallmeier, 2020, Nature Reviews Disease Primers.

CCDC151 Mutations Cause Primary Ciliary Dyskinesia by Disruption of the Outer Dynein Arm Docking Complex Formation

H. Omran, S. Letteboer, R. Roepman, 2014, American Journal of Human Genetics.

Homozygous loss-of-function mutations in MNS1 cause laterality defects and likely male infertility

H. Omran, S. Letteboer, R. Roepman, 2018, PLoS genetics.

DNAH11 Localization in the Proximal Region of Respiratory Cilia Defines Distinct Outer Dynein Arm Complexes.

R. Durbin, H. Omran, N. Katsanis, 2016, American journal of respiratory cell and molecular biology.

Dynein Dysfunction as a Cause of Primary Ciliary Dyskinesia and Other Ciliopathies

H. Omran, N. Loges, A. Becker-Heck, 2012 .

Heterotaxy and complex structural heart defects in a mutant mouse model of primary ciliary dyskinesia.

H. Omran, L. Leatherbury, Serena Y Tan, 2007, The Journal of clinical investigation.

Mislocalization of DNAH5 and DNAH9 in respiratory cells from patients with primary ciliary dyskinesia.

H. Omran, M. Fliegauf, J. Wildhaber, 2005, American journal of respiratory and critical care medicine.

Mutation analysis of NPHP6/CEP290 in patients with Joubert syndrome and Senior–Løken syndrome

I. Glass, H. Omran, F. Hildebrandt, 2007, Journal of Medical Genetics.

Zebrafish Ciliopathy Screen Plus Human Mutational Analysis Identifies C21orf59 and CCDC65 Defects as Causing Primary Ciliary Dyskinesia.

M. Rosenfeld, H. Omran, T. Hurd, 2013, American journal of human genetics.

Autosomal recessive rippling muscle disease with homozygous CAV3 mutations

H. Omran, C. Kubisch, U. Ketelsen, 2005, Annals of neurology.

A novel X-linked recessive mental retardation syndrome comprising macrocephaly and ciliary dysfunction is allelic to oral–facial–digital type I syndrome

Wei Chen, A. Latos-Bieleńska, H. Omran, 2006, Human Genetics.

Cyclin O (Ccno) functions during deuterosome‐mediated centriole amplification of multiciliated cells

Marcus Frank, Jörn Dengjel, Heymut Omran, 2015, The EMBO journal.

Mucociliary Wnt signaling promotes cilia biogenesis and beating

C. Niehrs, H. Omran, Carina Seidl, 2023, Nature Communications.

Defects in the cytoplasmic assembly of axonemal dynein arms cause morphological abnormalities and dysmotility in sperm cells leading to male infertility

H. Omran, P. Pennekamp, H. Olbrich, 2021, PLoS genetics.

Multicilin drives centriole biogenesis via E 2 f proteins Material Supplemental

H. Omran, Ian K Quigley, C. Kintner, 2014 .

Identification and analysis of axonemal dynein light chain 1 in primary ciliary dyskinesia patients.

R. Reinhardt, H. Omran, R. Sudbrak, 2005, American journal of respiratory cell and molecular biology.

Inner Dynein Arm Defects in Primary Ciliary Dyskinesia

H. Omran, D. Bilton, A. Shoemark, 2013 .

Mutations in a novel gene, NPHP3, cause adolescent nephronophthisis, tapeto-retinal degeneration and hepatic fibrosis

Bernhard Schermer, Thomas Benzing, Ralf Sudbrak, 2003, Nature Genetics.

Far lateral supracerebellar infratentorial approach for the treatment of upper brainstem gliomas: clinical experience with pediatric patients

H. Omran, V. Vougioukas, S. Gläsker, 2005, Child's Nervous System.

Mucopolysaccharidosis type IIID: 12 new patients and 15 novel mutations b

H. Omran, R. Wevers, A. Bertoli-Avella, 2010, Human mutation.

First reported nosocomial outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in a pediatric dialysis unit

H. Omran, A. Mellmann, M. Konrad, 2020, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Two novel mutations of the gene for Kir 1.1 (ROMK) in neonatal Bartter syndrome

H. Omran, F. Hildebrandt, R. Topaloğlu, 1998, Pediatric Nephrology.

Comparison of the Lung Clearance Index in Preschool Children with Primary Ciliary Dyskinesia and Cystic Fibrosis.

H. Omran, O. Sommerburg, I. Wojsyk-Banaszak, 2022, Chest.

Successful Extracorporeal Life Support in a Pediatric Hematopoietic Stem Cell Transplant Recipient With Periengraftment Respiratory Failure.

H. Omran, M. Ahlmann, J. Potratz, 2017, Journal of pediatric hematology/oncology.

Establishing an algorithm for molecular genetic diagnostics in 127 families with juvenile nephronophthisis.

H. Omran, F. Hildebrandt, E. Otto, 2001, Kidney international.

Phenotypic Spectrum of Children with Nephronophthisis and Related Ciliopathies.

Martin Lablans, Carsten Bergmann, Burkhard Tönshoff, 2017, Clinical journal of the American Society of Nephrology : CJASN.

Loss of CBY1 results in a ciliopathy characterized by features of Joubert syndrome

D. Misceo, H. Omran, N. Katsanis, 2020, Human mutation.

Mutations in SELENBP1, encoding a novel human methanethiol oxidase, cause extra-oral halitosis

H. Omran, R. Rodenburg, C. Gilissen, 2017, Nature Genetics.

Identification of a new gene locus for adolescent nephronophthisis, on chromosome 3q22 in a large Venezuelan pedigree.

F Hildebrandt, H Omran, N. Gretz, 2000, American journal of human genetics.

Nephrocystin specifically localizes to the transition zone of renal and respiratory cilia and photoreceptor connecting cilia.

H. Zentgraf, H. Omran, G. Pazour, 2006, Journal of the American Society of Nephrology : JASN.

RPGR mutations might cause reduced orientation of respiratory cilia

E. Haan, H. Omran, W. Berger, 2013, Pediatric pulmonology.

NMR spectroscopy of aminoacylase 1 deficiency, a novel inborn error of metabolism

Heymut Omran, H. Omran, U. Engelke, 2008, NMR in biomedicine.

Generation of induced pluripotent stem cell lines from a Crisponi/Cold induced sweating syndrome type 1 individual.

H. Omran, A. Röpke, L. Crisponi, 2020, Stem cell research.

Mutations in TP73 cause impaired mucociliary clearance and lissencephaly.

H. Omran, F. Alkuraya, E. Faqeih, 2021, American journal of human genetics.

Mutations in ACY 1 , the Gene Encoding Aminoacylase 1 , Cause a Novel Inborn Error of Metabolism

H. Omran, A. Kispert, U. Engelke, 2007 .

Mutations in ACY1, the gene encoding aminoacylase 1, cause a novel inborn error of metabolism.

H. Omran, A. Kispert, U. Engelke, 2006, American journal of human genetics.

Pathogenic gene variants in CCDC39, CCDC40, RSPH1, RSPH9, HYDIN, and SPEF2 cause defects of sperm flagella composition and male infertility

H. Omran, H. Olbrich, G. Dougherty, 2023, Frontiers in Genetics.

SARS-CoV-2 targets cortical neurons of 3D human brain organoids and shows neurodegeneration-like effects

A. Dilthey, H. Omran, D. Wieczorek, 2020, bioRxiv.

Lateralization defects and ciliary dyskinesia: lessons from algae.

Heymut Omran, H. Omran, P. Bouvagnet, 2003, Trends in genetics : TIG.

Candidate gene analysis of KIAA0678 encoding a DnaJ-like protein for adolescent nephronophthisis and Senior-Løken syndrome type 3

H. Omran, F. Hildebrandt, A. Volz, 2002, Cytogenetic and Genome Research.

Mapping of gene loci for nephronophthisis type 4 and Senior-Løken syndrome, to chromosome 1p36.

H. Omran, F. Hildebrandt, F. Rüschendorf, 2002, American journal of human genetics.

Evidence for further genetic heterogeneity in nephronophthisis.

H. Omran, C. Antignac, F. Hildebrandt, 2001, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

Human adolescent nephronophthisis: gene locus synteny with polycystic kidney disease in pcy mice.

H. Lehrach, H. Omran, S. Schnittger, 2001, Journal of the American Society of Nephrology : JASN.

LODVIEW: a computer program for the graphical evaluation of lod score results in exclusion mapping of human disease genes.

F Hildebrandt, A Pohlmann, H Omran, 1993, Computers and biomedical research, an international journal.

Imbalanced mitochondrial function provokes heterotaxy via aberrant ciliogenesis.

H. Omran, P. Walther, S. Ware, 2019, The Journal of clinical investigation.

Mutations in SELENBP1, encoding a novel human methanethiol oxidase, cause extraoral halitosis

H. Omran, R. Rodenburg, C. Gilissen, 2017, Nature Genetics.

Extracorporeal Membrane Oxygenation in Children With Cancer or Hematopoietic Cell Transplantation: Single-Center Experience in 20 Consecutive Patients

H. Omran, C. Rossig, A. Groll, 2021, Frontiers in Oncology.

Possible genotype-phenotype correlations in children with mild clinical course of Canavan disease.

D. Zafeiriou, H. Omran, J. Sass, 2005, Neuropediatrics.

The Rac1 regulator ELMO controls basal body migration and docking in multiciliated cells through interaction with Ezrin

O. Ronneberger, H. Omran, G. Walz, 2015, Development.

Homozygosity mapping of a gene locus for primary ciliary dyskinesia on chromosome 5p and identification of the heavy dynein chain DNAH5 as a candidate gene.

T. Wienker, H. Omran, F. Hildebrandt, 2000, American journal of respiratory cell and molecular biology.

L1CAM mutation in a boy with hydrocephalus and duplex kidneys

H. Omran, M. Liebau, A. Superti-Furga, 2007, Pediatric Nephrology.

First Reported Nosocomial Outbreak of Severe Acute Respiratory Syndrome Coronavirus 2 in a Pediatric Dialysis Unit

H. Omran, A. Mellmann, M. Konrad, 2021 .

The emerging genetics of primary ciliary dyskinesia.

H. Omran, T. Ferkol, M. Zariwala, 2011, Proceedings of the American Thoracic Society.

Study protocol, rationale and recruitment in a European multi-centre randomized controlled trial to determine the efficacy and safety of azithromycin maintenance therapy for 6 months in primary ciliary dyskinesia

H. Omran, A. Quittner, C. Kuehni, 2016, BMC Pulmonary Medicine.

Lethal phenotype of mice carrying a Sept11 null mutation

H. Omran, N. Loges, B. Zieger, 2011, Biological chemistry.

Primary Ciliary Dyskinesia.

H. Omran, P. Pennekamp, H. Olbrich, 2023, Presse medicale.

International BEAT-PCD consensus statement for infection prevention and control for primary ciliary dyskinesia in collaboration with ERN-LUNG PCD Core Network and patient representatives

H. Mussaffi, H. Omran, P. Yiallouros, 2021, ERJ Open Research.

NEUROLOGICAL FINDINGS IN AMINOACYLASE 1 DEFICIENCY

H. Omran, J. Sass, B. Woldseth, 2007, Neurology.

A human ciliopathy reveals essential functions for NEK10 in airway mucociliary clearance

Daniel T. Montoro, D. Sabatini, H. Omran, 2019, Nature Network Boston.

Congenital Myopathy with Arrest of Myogenesis Prior to Formation of Myotubes

H. Omran, B. Uhlenberg, M. Wagner, 2005, Neuropediatrics.

Identification of a novel LAMP2 mutation responsible for X-chromosomal dominant Danon disease.

H. Omran, H. Olbrich, N. Boehm, 2003, Neuropediatrics.

Positional Cloning and Linkage Analysis

H. Omran, F. Hildebrandt, 1999 .

Gene for Familial Juvenile Nephronophthisis: Refining the Map and Defining Flanking Markers

H. Omran, C. Antignac, F. Hildebrandt, 2006 .

Male minipuberty in human and non-human primates - planting the seeds of future fertility.

H. Omran, A. Juul, S. Schlatt, 2023, Reproduction.

Exome Capture Reveals ZNF423 and CEP164 Mutations, Linking Renal Ciliopathies to DNA Damage Response Signaling

Colin A. Johnson, S. Levy, Shaohui Wang, 2012, Cell.

BRAF gene duplication constitutes a mechanism of MAPK pathway activation in low-grade astrocytomas.

G. Reifenberger, P. Lichter, S. Pfister, 2008, The Journal of clinical investigation.

High Prevalence of Respiratory Ciliary Dysfunction in Congenital Heart Disease Patients With Heterotaxy

M. Barmada, H. Omran, L. Leatherbury, 2012, Circulation.

Imbalanced mitochondrial function provokes heterotaxy via aberrant ciliogenesis.

H. Omran, P. Walther, S. Ware, 2019, The Journal of clinical investigation.

Loss-of-Function GAS8 Mutations Cause Primary Ciliary Dyskinesia and Disrupt the Nexin-Dynein Regulatory Complex.

H. Omran, P. Pennekamp, J. Altmüller, 2015, American journal of human genetics.

Zebrafish Ciliopathy Screen Plus Human Mutational Analysis Identifies C21orf59 and CCDC65 Defects as Causing Primary Ciliary Dyskinesia.

M. Rosenfeld, H. Omran, T. Hurd, 2013, American journal of human genetics.

Mucopolysaccharidosis type IIID: 12 new patients and 15 novel mutations b

H. Omran, R. Wevers, A. Bertoli-Avella, 2010, Human mutation.

Molecular defects in primary ciliary dyskinesia are associated with agenesis of the frontal and sphenoid paranasal sinuses and chronic rhinosinusitis

H. Omran, J. Raidt, Andre Schramm, 2023, Frontiers in Molecular Biosciences.

TUBB4B variants specifically impact ciliary function, causing a ciliopathic spectrum

K. Heimdal, E. Jabs, H. Omran, 2022, medRxiv.

Ciliopathy patient variants reveal organelle-specific functions for TUBB4B in axonemal microtubules

A. Fulton, E. Jabs, H. Omran, 2024, Science.

The von Hippel-Lindau tumor suppressor protein controls ciliogenesis by orienting microtubule growth

H. Zentgraf, R. Nitschke, H. Omran, 2006, The Journal of cell biology.