Hans-Peter Lenhof

Christina Backes, Eckart Meese, Hans-Peter Lenhof, 2004, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

BioMiner - modeling, analyzing, and visualizing biochemical pathways and networks

Erich Bornberg-Bauer, Hans-Peter Lenhof, Markus Eiglsperger, 2002, ECCB.

Stable serum miRNA profiles as potential tool for non-invasive lung cancer diagnosis

Eckart Meese, Andreas Keller, Hans-Peter Lenhof, 2011, RNA biology.

A high‐resolution map of the human small non‐coding transcriptome

Christina Backes, Benjamin Meder, Eckart Meese, 2018, Bioinform..

An estimate of the total number of true human miRNAs

Christina Backes, Eckart Meese, Andreas Keller, 2019, Nucleic acids research.

SUMO pathway inhibition targets an aggressive pancreatic cancer subtype

W. Weichert, R. Rad, Hans-Peter Lenhof, 2020, Gut.

Myeloid cell RelA/p65 promotes lung cancer proliferation through Wnt/β-catenin signaling in murine and human tumor cells

Hans-Peter Lenhof, R. Bohle, R. Schmid, 2014, Oncogene.

Specific peripheral miRNA profiles for distinguishing lung cancer from COPD.

Eckart Meese, Andreas Keller, Hans-Peter Lenhof, 2011, Lung cancer.

High-throughput miRNA profiling of human melanoma blood samples

Eckart Meese, Andreas Keller, Hans-Peter Lenhof, 2010, BMC Cancer.

RegulatorTrail: a web service for the identification of key transcriptional regulators

Christina Backes, Eckart Meese, Marcel H. Schulz, 2017, Nucleic Acids Res..

Frequent overexpression of the genes FXR1, CLAPM1 and EIF4G located on amplicon 3q26‐27 in squamous cell carcinoma of the lung

Hans-Peter Lenhof, A. Keller, E. Meese, 2007, International journal of cancer.

miRTargetLink 2.0—interactive miRNA target gene and target pathway networks

Hans-Peter Lenhof, A. Keller, N. Ludwig, 2021, Nucleic Acids Res..

Cas9-mediated knockout of Ndrg2 enhances the regenerative potential of dendritic cells for wound healing

Lei S. Qi, M. Longaker, Hans-Peter Lenhof, 2022, bioRxiv.

GeneTrail: A Framework for the Analysis of High-Throughput Profiles

Hans-Peter Lenhof, A. Keller, C. Backes, 2021, Frontiers in Molecular Biosciences.

Detecting Dysregulated Processes and Pathways

Daniel Stöckel, Hans-Peter Lenhof, Hans-Peter Lenhof, 2014 .

Machine Learning to Detect Alzheimer’s Disease from Circulating Non-coding RNAs

Christina Backes, Eckart Meese, Andreas Keller, 2019, bioRxiv.

Genome-wide MicroRNA Expression Profiles in COPD: Early Predictors for Cancer Development

Christina Backes, Eckart Meese, Andreas Keller, 2018, Genom. Proteom. Bioinform..

miRCarta: a central repository for collecting miRNA candidates

Christina Backes, Eckart Meese, Andreas Keller, 2017, Nucleic Acids Res..

Combining miRNA and mRNA Expression Profiles in Wilms Tumor Subtypes

Christina Backes, Eckart Meese, Andreas Keller, 2016, International journal of molecular sciences.

Wrinkle in the plan: miR-34a-5p impacts chemokine signaling by modulating CXCL10/CXCL11/CXCR3-axis in CD4+, CD8+ T cells, and M1 macrophages

Hans-Peter Lenhof, A. Keller, E. Meese, 2020, Journal for ImmunoTherapy of Cancer.

Pattern of Serum Autoantibodies Allows Accurate Distinction between a Tumor and Pathologies of the Same Organ

Eckart Meese, Andreas Keller, Hans-Peter Lenhof, 2008, Clinical Cancer Research.

DrugTargetInspector: An assistance tool for patient treatment stratification

Eckart Meese, Andreas Keller, Hans-Peter Lenhof, 2016, International journal of cancer.

Toward an early diagnosis of lung cancer: An autoantibody signature for squamous cell lung carcinoma

Eckart Meese, Andreas Keller, Hans-Peter Lenhof, 2008, International journal of cancer.

A dictionary on microRNAs and their putative target pathways

Christina Backes, Eckart Meese, Andreas Keller, 2010, Nucleic acids research.

miRTrail - a comprehensive webserver for analyzing gene and miRNA patterns to enhance the understanding of regulatory mechanisms in diseases

C. Laczny, Hans-Peter Lenhof, J. Haas, 2012, BMC Bioinformatics.

miRNAs in lung cancer - Studying complex fingerprints in patient's blood cells by microarray experiments

Eckart Meese, Andreas Keller, Hans-Peter Lenhof, 2009, BMC Cancer.

Paired proteomics, transcriptomics and miRNomics in non-small cell lung cancers: known and novel signaling cascades

S. Tenzer, Hans-Peter Lenhof, A. Franke, 2016, Oncotarget.

Complex humoral immune response against a benign tumor: frequent antibody response against specific antigens as diagnostic targets.

Christina Backes, Eckart Meese, Andreas Keller, 2005, Proceedings of the National Academy of Sciences of the United States of America.

EDISON-WMW: Exact Dynamic Programing Solution of the Wilcoxon–Mann–Whitney Test

Christina Backes, Eckart Meese, Andreas Keller, 2016, Genom. Proteom. Bioinform..

Time-resolved RNA signatures of CD4+ T cells in Parkinson’s disease

Hans-Peter Lenhof, A. Keller, E. Meese, 2023, Cell Death Discovery.

Phylogenomics with paralogs

Martin Middendorf, Hans-Peter Lenhof, Peter F. Stadler, 2015, Proceedings of the National Academy of Sciences.

Phylogenetics from paralogs

Hans-Peter Lenhof, Peter F. Stadler, Nicolas Wieseke, 2014 .

Genetic alterations of the SUMO isopeptidase SENP6 drive lymphomagenesis and genetic instability in diffuse large B-cell lymphoma

A. Baiker, R. Rad, J. Slotta-Huspenina, 2022, Nature communications.

Yamada Analyzer - A Tool for Fast Calculation of Genomic Attributes

Thomas Lengauer, Hans-Peter Lenhof, Holger Jung, 2006 .

Proceedings of the European Conference on Computational Biology (ECCB 2002), October 6-9, 2002, Saarbrücken, Germany

Thomas Lengauer, Hans-Peter Lenhof, Thomas Lengauer, 2002, European Conference on Computational Biology.

miRPathDB: a new dictionary on microRNAs and target pathways

Christina Backes, Eckart Meese, Andreas Keller, 2016, Nucleic Acids Res..

Genome wide expression profiling identifies specific deregulated pathways in meningioma

Hans-Peter Lenhof, A. Keller, C. Mawrin, 2009, International journal of cancer.

Immunogenicity of autoantigens

Christina Backes, Eckart Meese, Andreas Keller, 2011, BMC Genomics.

Electrostatic potentials of proteins in water: a structured continuum approach

Hans-Peter Lenhof, Sergej Rjasanow, Oliver Kohlbacher, 2007, Bioinform..

q-gram based database searching using a suffix array (QUASAR)

Martin Vingron, Hans-Peter Lenhof, Paolo Ferragina, 1999, RECOMB.

Novel autoantigens immunogenic in COPD patients

Hans-Peter Lenhof, A. Keller, P. Leidinger, 2009, Respiratory research.

A minimally invasive multiple marker approach allows highly efficient detection of meningioma tumors

Eckart Meese, Andreas Keller, Hans-Peter Lenhof, 2006, BMC Bioinformatics.

miRTrail - a comprehensive webserver for analyzing gene and miRNA patterns to enhance the understanding of regulatory mechanisms in diseases

Christina Backes, Jan Haas, Hugo A. Katus, 2012, BMC Bioinformatics.

Systematic permutation testing in GWAS pathway analyses: identification of genetic networks in dilated cardiomyopathy and ulcerative colitis

Karen S. Frese, H. Wichmann, W. Lieb, 2014, BMC Genomics.

miR-34a: a new player in the regulation of T cell function by modulation of NF-κB signaling

Hans-Peter Lenhof, A. Keller, E. Meese, 2019, Cell Death & Disease.

Modulation of intracellular calcium signaling by microRNA-34a-5p

Hans-Peter Lenhof, A. Keller, E. Meese, 2018, Cell Death & Disease.

Identification of lung cancer with high sensitivity and specificity by blood testing

Eckart Meese, Andreas Keller, Hans-Peter Lenhof, 2010, Respiratory research.

Large-scale antibody profiling of human blood sera: The future of molecular diagnosis

Eckart Meese, Andreas Keller, Joachim Weickert, 2009, Informatik-Spektrum.

Increased Seroreactivity to Glioma-Expressed Antigen 2 in Brain Tumor Patients under Radiation

Hans-Peter Lenhof, A. Keller, E. Meese, 2008, PloS one.

Evaluating the Use of Circulating MicroRNA Profiles for Lung Cancer Detection in Symptomatic Patients.

Christina Backes, Benjamin Meder, Eckart Meese, 2020, JAMA oncology.

Development of a fluorescence-based assay for screening of modulators of human organic anion transporter 1B3 (OATP1B3).

O. Kohlbacher, Hans-Peter Lenhof, C. Lehr, 2006, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Low miR-150-5p and miR-320b Expression Predicts Reduced Survival of COPD Patients

Hans-Peter Lenhof, C. Vogelmeier, U. Fischer, 2019, Cells.

Integrated quantitative proteomic and transcriptomic analysis of lung tumor and control tissue: a lung cancer showcase

S. Tenzer, A. Hildebrandt, Hans-Peter Lenhof, 2016, Oncotarget.

Transcriptome analysis by GeneTrail revealed regulation of functional categories in response to alterations of iron homeostasis in Arabidopsis thaliana

Christina Backes, Andreas Keller, Hans-Peter Lenhof, 2011, BMC Plant Biology.

Treatment-independent miRNA signature in blood of wilms tumor patients

M. Gessler, Hans-Peter Lenhof, A. Keller, 2012, BMC Genomics.

Treatment-independent miRNA signature in blood of wilms tumor patients

Christina Backes, Eckart Meese, Andreas Keller, 2012, BMC Genomics.

miR-34a: a new player in the regulation of T cell function by modulation of NF-κB signaling

Hans-Peter Lenhof, A. Keller, E. Meese, 2019, Cell Death & Disease.

Combination of Autoantibody Signature with PSA Level Enables a Highly Accurate Blood-Based Differentiation of Prostate Cancer Patients from Patients with Benign Prostatic Hyperplasia

Hans-Peter Lenhof, B. Wullich, A. Keller, 2015, PloS one.

Computation of significance scores of unweighted Gene Set Enrichment Analyses

Christina Backes, Andreas Keller, Hans-Peter Lenhof, 2007, BMC Bioinformatics.

A combinatorial approach to protein docking with flexible side-chains

Ernst Althaus, Hans-Peter Lenhof, Oliver Kohlbacher, 2000, RECOMB '00.

GeneTrailExpress: a web-based pipeline for the statistical evaluation of microarray experiments

Hans-Peter Lenhof, Oliver Kohlbacher, Andreas Keller, 2008, BMC Bioinformatics.

NetworkTrail - a web service for identifying and visualizing deregulated subnetworks

Christina Backes, Andreas Keller, Michael Kaufmann, 2013, Bioinform..

PresentaBALL — A powerful package for presentations and lessons in structural biology

Sabine C. Mueller, Hans-Peter Lenhof, Anna Katharina Dehof, 2013, 2013 IEEE Symposium on Biological Data Visualization (BioVis).

BiNA: A Visual Analytics Tool for Biological Network Data

Hans-Peter Lenhof, Oliver Kohlbacher, Michael Kaufmann, 2014, PloS one.

BN++ – A Biological Information System

Christina Backes, Hans-Peter Lenhof, Oliver Kohlbacher, 2008, J. Integr. Bioinform..

Novel formulation of nonlocal electrostatics.

O. Kohlbacher, A. Hildebrandt, Hans-Peter Lenhof, 2004, Physical review letters.

Protein- versus peptide fractionation in the first dimension of two-dimensional high-performance liquid chromatography-matrix-assisted laser desorption/ionization tandem mass spectrometry for qualitative proteome analysis of tissue samples.

Hans-Peter Lenhof, C. Huber, A. Keller, 2010, Journal of chromatography. A.

BALL-SNP: combining genetic and structural information to identify candidate non-synonymous single nucleotide polymorphisms

Sabine C. Mueller, Hans-Peter Lenhof, O. Kalinina, 2015, Genome Medicine.

NightShift: NMR shift inference by general hybrid model training - a framework for NMR chemical shift prediction

Anna Katharina Dehof, A. Hildebrandt, Hans-Peter Lenhof, 2013, BMC Bioinformatics.

BALL - biochemical algorithms library 1.3

Sabine C. Mueller, Hans-Peter Lenhof, Oliver Kohlbacher, 2010, BMC Bioinformatics.

BALLView: a tool for research and education in molecular modeling

Hans-Peter Lenhof, Oliver Kohlbacher, Andreas Hildebrandt, 2006, Bioinform..

Automated Bond Order Assignment as an Optimization Problem

Hans-Peter Lenhof, Anna Katharina Dehof, Andreas Hildebrandt, 2011, GCB.

SePaCS—a web-based application for classification of seroreactivity profiles

Eckart Meese, Andreas Keller, Hans-Peter Lenhof, 2007, Nucleic Acids Res..

Using Persistent Data Structures for Adding Range Restrictions to Searching Problems

Michiel H. M. Smid, Hans-Peter Lenhof, M. Smid, 1994, RAIRO Theor. Informatics Appl..

New contact measures for the protein docking problem

Hans-Peter Lenhof, Hans-Peter Lenhof, 1997, RECOMB '97.

An integer linear programming approach for finding deregulated subgraphs in regulatory networks

Matthias Hein, Hans-Peter Lenhof, D. Maisel, 2011, Nucleic acids research.

ClinOmicsTrailbc: a visual analytics tool for breast cancer treatment stratification

Christina Backes, Eckart Meese, Andreas Keller, 2019, Bioinform..

Simulating synthetic polymer chains in parallel

Hans-Peter Lenhof, Bernd Jung, Peter Müller, 1999, Future Gener. Comput. Syst..

CausalTrail: Testing hypothesis using causal Bayesian networks

K. Sachs, Hans-Peter Lenhof, Florian Schmidt, 2015, F1000Research.

Computation of significance scores of unweighted Gene Set Enrichment Analyses

Hans-Peter Lenhof, A. Keller, C. Backes, 2007, BMC Bioinformatics.

A NMR-spectra-based scoring function for protein docking

Hans-Peter Lenhof, Oliver Kohlbacher, Andreas Hildebrandt, 2001, RECOMB.

BNDB – The Biochemical Network Database

Christina Backes, Michael Kaufmann, Hans-Peter Lenhof, 2007, BMC Bioinformatics.

A branch-and-cut algorithm for multiple sequence alignment

Kurt Mehlhorn, Petra Mutzel, Hans-Peter Lenhof, 1997, RECOMB '97.

Novel immunogenic antigens increase classification accuracy in meningioma to 93.84%

J. Weickert, Hans-Peter Lenhof, B. Burgeth, 2011, International journal of cancer.

Efficient computation of root mean square deviations under rigid transformations

Ernst Althaus, Thomas Lengauer, Hans-Peter Lenhof, 2014, J. Comput. Chem..

Circulating serum miRNAs as potential biomarkers for nephroblastoma

Hans-Peter Lenhof, A. Keller, C. Backes, 2015, Pediatric blood & cancer.

Static and Dynamic Algorithms for k-Point Clustering Problems

Michiel H. M. Smid, Amitava Datta, Hans-Peter Lenhof, 1993, J. Algorithms.

Ballaxy: Web Services for Structural Bioinformatics

Hans-Peter Lenhof, Jens Krüger, Oliver Kohlbacher, 2015, Bioinform..