V. Tugarinov

发表

NMR structure of an anti-gp120 antibody complex with a V3 peptide reveals a surface important for co-receptor binding.

V. Tugarinov, A. Zvi, R. Levy, 2000, Structure.

Ligand-induced structural changes to maltodextrin-binding protein as studied by solution NMR spectroscopy.

L. Kay, V. Tugarinov, R. Muhandiram, 2001, Journal of molecular biology.

Backbone dynamics of escherichia coli adenylate kinase at the extreme stages of the catalytic cycle studied by (15)N NMR relaxation.

E. Meirovitch, V. Tugarinov, Y. E. Shapiro, 2000, Biochemistry.

Refined solution structure of the 82-kDa enzyme malate synthase G from joint NMR and synchrotron SAXS restraints

Jill Trewhella, Ad Bax, Alexander Grishaev, 2008, Journal of biomolecular NMR.

Solution structures of a highly insecticidal recombinant scorpion alpha-toxin and a mutant with increased activity.

V. Tugarinov, J. Anglister, M. Gurevitz, 1997, Biochemistry.

Sodium channel modifiers from scorpion venom: structure-activity relationship, mode of action and application.

V. Tugarinov, J. Anglister, M. Adams, 1998, Toxicon : official journal of the International Society on Toxinology.

Accurate measurements of the effects of deuteration at backbone amide positions on the chemical shifts of 15N, 13Cα, 13Cβ, 13CO and 1Hα nuclei in proteins

V. Tugarinov, Daoning Zhang, 2013, Journal of Biomolecular NMR.

Selective detection of ¹³CHD₂ signals from a mixture of ¹³CH₃/¹³CH₂D/¹³CHD₂ methyl isotopomers in proteins.

V. Tugarinov, Xinli Liao, 2011, Journal of magnetic resonance.

Nuclear magnetic resonance spectroscopy of high-molecular-weight proteins.

L. Kay, V. Tugarinov, P. Hwang, 2004, Annual review of biochemistry.

Selective backbone labeling of proteins using {1,2-13C2}-pyruvate as carbon source

V. Tugarinov, Chenyun Guo, C. Geng, 2009, Journal of biomolecular NMR.

Indirect use of deuterium in solution NMR studies of protein structure and hydrogen bonding.

V. Tugarinov, 2014, Progress in nuclear magnetic resonance spectroscopy.

Comparison of 13CH3, 13CH2D, and 13CHD2 methyl labeling strategies in proteins

L. Kay, V. Tugarinov, Jason E. Ollerenshaw, 2005, Journal of biomolecular NMR.

Ile, Leu, and Val methyl assignments of the 723-residue malate synthase G using a new labeling strategy and novel NMR methods.

L. Kay, V. Tugarinov, Lewis E Kay, 2003, Journal of the American Chemical Society.

L. Kay, V. Tugarinov, P. Hwang, 2003, Journal of the American Chemical Society.

Side chain assignments of Ile delta 1 methyl groups in high molecular weight proteins: an application to a 46 ns tumbling molecule.

L. Kay, V. Tugarinov, 2003, Journal of the American Chemical Society.

Simultaneous measurement of 1H–15N and Methyl 1Hm–13Cm residual dipolar couplings in large proteins

V. Tugarinov, R. Godoy-Ruiz, Xinli Liao, 2011, Journal of biomolecular NMR.

Interaction of Huntingtin Exon-1 Peptides with Lipid-Based Micellar Nanoparticles Probed by Solution NMR and Q-Band Pulsed EPR.

G. Clore, C. Schwieters, V. Tugarinov, 2018, Journal of the American Chemical Society.

Quantitative Exchange NMR-Based Analysis of Huntingtin-SH3 Interactions Suggests an Allosteric Mechanism of Inhibition of Huntingtin Aggregation.

G. Clore, V. Tugarinov, A. Ceccon, 2021, Journal of the American Chemical Society.

Dipolar dynamic frequency shifts in multiple‐quantum spectra of methyl groups in proteins: correlation with side‐chain motion

L. Kay, V. Tugarinov, Jason E. Ollerenshaw, 2006, Magnetic resonance in chemistry : MRC.

Global Dynamics of a Protein on the Surface of Anisotropic Lipid Nanoparticles Derived from Relaxation-Based NMR Spectroscopy.

G. Clore, J. Louis, V. Tugarinov, 2022, The journal of physical chemistry. B.

Targeting a Dark Excited State of HIV-1 Nucleocapsid by Antiretroviral Thioesters Revealed by NMR Spectroscopy.

G. Clore, L. Deshmukh, V. Tugarinov, 2018, Angewandte Chemie.

Quantitative NMR analysis of the kinetics of prenucleation oligomerization and aggregation of pathogenic huntingtin exon-1 protein

G. Clore, V. Tugarinov, A. Ceccon, 2022, Proceedings of the National Academy of Sciences of the United States of America.

NMR probing of invisible excited states using selectively labeled RNAs

V. Tugarinov, Regan M. LeBlanc, A. Longhini, 2018, Journal of Biomolecular NMR.

3D-TROSY-based backbone and ILV-methyl resonance assignments of a 319-residue homodimer from a single protein sample

V. Tugarinov, Anna Krejcirikova, Anna Krejcirikova, 2012, Journal of Biomolecular NMR.

1H,13C-1H,1H Dipolar Cross-correlated Spin Relaxation in Methyl Groups

L. Kay, V. Tugarinov, 2004, Journal of biomolecular NMR.

Accurate measurements of the effects of deuteration at backbone amide positions on the chemical shifts of 15N, 13Cα, 13Cβ, 13CO and 1Hα nuclei in proteins

V. Tugarinov, Daoning Zhang, 2013, Journal of Biomolecular NMR.

Experimental approaches for NMR studies of side-chain dynamics in high-molecular-weight proteins.

V. Tugarinov, R. Sprangers, D. Sheppard, 2010, Progress in nuclear magnetic resonance spectroscopy.

Carbon relaxation in 13Cα-Hα and 13Cα-Dα spin pairs as a probe of backbone dynamics in proteins.

R. Brüschweiler, V. Tugarinov, Dong Long, 2013, The journal of physical chemistry. B.

Quantitative NMR studies of high molecular weight proteins: application to domain orientation and ligand binding in the 723 residue enzyme malate synthase G.

L. Kay, V. Tugarinov, Lewis E Kay, 2003, Journal of molecular biology.

Probing slow dynamics in high molecular weight proteins by methyl-TROSY NMR spectroscopy: application to a 723-residue enzyme.

Dmitry M Korzhnev, Karin Kloiber, L. Kay, 2004, Journal of the American Chemical Society.

Selective 1H-13C NMR spectroscopy of methyl groups in residually protonated samples of large proteins

V. Tugarinov, Chenyun Guo, 2010, Journal of biomolecular NMR.

4D 1H-13C NMR spectroscopy for assignments of alanine methyls in large and complex protein structures.

V. Tugarinov, D. Sheppard, Chenyun Guo, 2009, Journal of the American Chemical Society.

Stereospecific NMR assignments of prochiral methyls, rotameric states and dynamics of valine residues in malate synthase G.

L. Kay, V. Tugarinov, 2004, Journal of the American Chemical Society.

An Isotope Labeling Strategy for Methyl TROSY Spectroscopy

L. Kay, V. Tugarinov, 2004, Journal of biomolecular NMR.

Four-dimensional NMR spectroscopy of a 723-residue protein: chemical shift assignments and secondary structure of malate synthase g.

L. Kay, V. Tugarinov, A. Ayed, 2002, Journal of the American Chemical Society.

An NMR experiment for simultaneous TROSY-based detection of amide and methyl groups in large proteins.

V. Tugarinov, Daoning Zhang, Chenyun Guo, 2008, Journal of the American Chemical Society.

Four‐bond deuterium isotope effects on the chemical shifts of amide nitrogens in proteins

V. Tugarinov, 2013, Magnetic resonance in chemistry : MRC.

Precision measurements of deuterium isotope effects on the chemical shifts of backbone nuclei in proteins: correlations with secondary structure.

V. Tugarinov, Hechao Sun, 2012, The journal of physical chemistry. B.

Desorption parameters in the synthesis of 2-methylpyrazine over Zn−Cr−O

A. V. Vishnyakov, V. Tugarinov, L. Forni, 1993 .

Isotope labeling strategies for the study of high-molecular-weight proteins by solution NMR spectroscopy

L. Kay, V. Tugarinov, V. Kanelis, 2006, Nature Protocols.

High-resolution four-dimensional 1H-13C NOE spectroscopy using methyl-TROSY, sparse data acquisition, and multidimensional decomposition.

Vladislav Yu Orekhov, Ilghiz Ibraghimov, L. Kay, 2005, Journal of the American Chemical Society.

Binding kinetics and substrate selectivity in HIV-1 protease−Gag interactions probed at atomic resolution by chemical exchange NMR

G. Clore, J. Louis, L. Deshmukh, 2017, Proceedings of the National Academy of Sciences.

Intrinsic unfoldase/foldase activity of the chaperonin GroEL directly demonstrated using multinuclear relaxation-based NMR

G. Clore, V. Tugarinov, D. Libich, 2015, Proceedings of the National Academy of Sciences.

Characterizing methyl-bearing side chain contacts and dynamics mediating amyloid β protofibril interactions using ¹³C(methyl)-DEST and lifetime line broadening.

Nicolas L. Fawzi, G. Clore, Jinfa Ying, 2014, Angewandte Chemie.

Methyl TROSY: explanation and experimental verification

L. Kay, V. Tugarinov, Jason E. Ollerenshaw, 2003 .

Alanine methyl groups as NMR probes of molecular structure and dynamics in high-molecular-weight proteins.

V. Tugarinov, R. Godoy-Ruiz, Chenyun Guo, 2010, Journal of the American Chemical Society.

An optimized relaxation-based coherence transfer NMR experiment for the measurement of side-chain order in methyl-protonated, highly deuterated proteins.

L. Kay, V. Tugarinov, Hechao Sun, 2011, The journal of physical chemistry. B.

Interaction of the bacterial division regulator MinE with lipid bicelles studied by NMR spectroscopy

G. Clore, C. Schwieters, V. Tugarinov, 2023, The Journal of biological chemistry.

NMR methods for exploring 'dark' states in ligand binding and protein-protein interactions.

G. Clore, V. Tugarinov, A. Ceccon, 2021, Progress in nuclear magnetic resonance spectroscopy.

An S/T motif controls reversible oligomerization of the Hsp40 chaperone DNAJB6b through subtle reorganization of a β sheet backbone

G. Clore, V. Tugarinov, T. Karamanos, 2020, Proceedings of the National Academy of Sciences.

Estimating side-chain order in methyl-protonated, perdeuterated proteins via multiple-quantum relaxation violated coherence transfer NMR spectroscopy

V. Tugarinov, R. Godoy‐Ruiz, Hechao Sun, 2012, Journal of biomolecular NMR.

Probing side-chain dynamics in proteins by the measurement of nine deuterium relaxation rates per methyl group.

R. Brüschweiler, V. Tugarinov, Da-Wei Li, 2012, The journal of physical chemistry. B.

Variation in quadrupole couplings of alpha deuterons in ubiquitin suggests the presence of C(alpha)-H(alpha)...O=C hydrogen bonds.

R. Brüschweiler, V. Tugarinov, Da-Wei Li, 2010, Journal of the American Chemical Society.

Estimating quadrupole couplings of amide deuterons in proteins from direct measurements of 2H spin relaxation rates.

V. Tugarinov, D. Sheppard, 2010, Journal of magnetic resonance.

Deuterium spin probes of backbone order in proteins: 2H NMR relaxation study of deuterated carbon alpha sites.

R. Brüschweiler, V. Tugarinov, Da-Wei Li, 2009, Journal of the American Chemical Society.

A novel view of domain flexibility in E. coli adenylate kinase based on structural mode-coupling (15)N NMR relaxation.

Jack H Freed, E. Meirovitch, J. Freed, 2002, Journal of molecular biology.

Solution Structure of an Antibody-Bound HIV-1IIIB V3 Peptide: A Cis Proline Turn Linking Two β-hairpin Strands

V. Tugarinov, J. Anglister, 2000, Journal of biomolecular structure & dynamics.

A cis proline turn linking two β-hairpin strands in the solution structure of an antibody-bound HIV-1IIIB V3 peptide

Rina Levy, Anat Zvi, V. Tugarinov, 1999, Nature Structural Biology.

Letter to the Editor: Backbone and Cβ assignments of the anti-gp120 antibody Fv fragment complexed with an antigenic peptide

V. Tugarinov, R. Levy, J. Anglister, 1999, Journal of biomolecular NMR.

Domain flexibility in ligand-free and inhibitor-bound Escherichia coli adenylate kinase based on a mode-coupling analysis of 15N spin relaxation.

Jack H Freed, E. Meirovitch, J. Freed, 2002, Biochemistry.

Unraveling the structure and dynamics of the human DNAJB6b chaperone by NMR reveals insights into Hsp40-mediated proteostasis

G. Clore, V. Tugarinov, T. Karamanos, 2019, Proceedings of the National Academy of Sciences.

Large interdomain rearrangement triggered by suppression of micro- to millisecond dynamics in bacterial Enzyme I

G. Clore, A. Grishaev, C. Schwieters, 2014, Nature Communications.

Probing side-chain dynamics in high molecular weight proteins by deuterium NMR spin relaxation: an application to an 82-kDa enzyme.

L. Kay, V. Tugarinov, Jason E. Ollerenshaw, 2005, Journal of the American Chemical Society.

Kinetic Cooperativity in Human Pancreatic Glucokinase Originates from Millisecond Dynamics of the Small Domain.

R. Brüschweiler, V. Tugarinov, Fengli Zhang, 2015, Angewandte Chemie.

Probing Side-Chain Dynamics in Proteins by NMR Relaxation of Isolated 13C Magnetization Modes in 13CH3 Methyl Groups.

V. Tugarinov, A. Ceccon, G. Marius Clore, 2021, The journal of physical chemistry. B.

Estimating side-chain order in [U-2H;13CH3]-labeled high molecular weight proteins from analysis of HMQC/HSQC spectra.

L. Kay, V. Tugarinov, 2013, The journal of physical chemistry. B.

Observation and relaxation properties of individual fast-relaxing proton transitions in [¹³CH₃]-methyl-labeled, deuterated proteins.

V. Tugarinov, Hechao Sun, 2012, Journal of magnetic resonance.

Estimating side-chain order in methyl-protonated, perdeuterated proteins via multiple-quantum relaxation violated coherence transfer NMR spectroscopy

V. Tugarinov, R. Godoy‐Ruiz, Hechao Sun, 2012, Journal of Biomolecular NMR.

NMR probing of invisible excited states using selectively labeled RNAs

V. Tugarinov, Regan M. LeBlanc, T. K. Dayie, 2018, Journal of biomolecular NMR.

Confinement and Stabilization of Fyn SH3 Folding Intermediate Mimetics within the Cavity of the Chaperonin GroEL Demonstrated by Relaxation-Based NMR.

G. Clore, R. Ghirlando, V. Tugarinov, 2017, Biochemistry.

Probing the Binding Modes of a Multidomain Protein to Lipid-based Nanoparticles by Relaxation-based NMR.

G. Clore, V. Tugarinov, D. Fushman, 2017, The journal of physical chemistry letters.

Global Dynamics and Exchange Kinetics of a Protein on the Surface of Nanoparticles Revealed by Relaxation-Based Solution NMR Spectroscopy.

A. Bax, G. Clore, V. Tugarinov, 2016, Journal of the American Chemical Society.

TiO2 Nanoparticles Catalyze Oxidation of Huntingtin Exon 1-Derived Peptides Impeding Aggregation: A Quantitative NMR Study of Binding and Kinetics.

G. Clore, V. Tugarinov, A. Ceccon, 2018, Journal of the American Chemical Society.

Probing initial transient oligomerization events facilitating Huntingtin fibril nucleation at atomic resolution by relaxation-based NMR

Thomas Schmidt, G. Marius Clore, Charles D. Schwieters, 2019, Proceedings of the National Academy of Sciences.

Probing the mechanism of inhibition of amyloid-β(1–42)–induced neurotoxicity by the chaperonin GroEL

G. Clore, J. Louis, R. Ghirlando, 2018, Proceedings of the National Academy of Sciences.

3D-TROSY-based backbone and ILV-methyl resonance assignments of a 319-residue homodimer from a single protein sample

V. Tugarinov, Anna Krejcirikova, 2012, Journal of biomolecular NMR.

Solution NMR evidence for symmetry in functionally or crystallographically asymmetric homodimers.

V. Tugarinov, D. Gallagher, R. Godoy‐Ruiz, 2011, Journal of the American Chemical Society.

Methyl Groups as Probes of Structure and Dynamics in NMR Studies of High‐Molecular‐Weight Proteins

L. Kay, V. Tugarinov, Vitali Tugarinov, 2005, Chembiochem : a European journal of chemical biology.

A model of a gp120 V3 peptide in complex with an HIV-neutralizing antibody based on NMR and mutant cycle-derived constraints.

A. Horovitz, V. Tugarinov, A. Zvi, 2000, European journal of biochemistry.

Identification of HN-methyl NOEs in large proteins using simultaneous amide-methyl TROSY-based detection

V. Tugarinov, Chenyun Guo, 2009, Journal of biomolecular NMR.

A structural mode-coupling approach to 15N NMR relaxation in proteins.

E. Meirovitch, J. Freed, V. Tugarinov, 2001, Journal of the American Chemical Society.

Relaxation rates of degenerate 1H transitions in methyl groups of proteins as reporters of side-chain dynamics.

L. Kay, V. Tugarinov, 2006, Journal of the American Chemical Society.

Quantitative 13C and 2H NMR relaxation studies of the 723-residue enzyme malate synthase G reveal a dynamic binding interface.

L. Kay, V. Tugarinov, 2005, Biochemistry.

Exchange saturation transfer and associated NMR techniques for studies of protein interactions involving high-molecular-weight systems

G. Clore, V. Tugarinov, 2019, Journal of Biomolecular NMR.

The energetics of a three-state protein folding system probed by high-pressure relaxation dispersion NMR spectroscopy.

G. Clore, V. Tugarinov, D. Libich, 2015, Angewandte Chemie.

Solution NMR-derived global fold of a monomeric 82-kDa enzyme.

Wing-Yiu Choy, Vladislav Yu Orekhov, L. Kay, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Determining methyl sidechain conformations in a CS-ROSETTA model using methyl 1H-13C residual dipolar couplings

G. Clore, V. Tugarinov, T. Karamanos, 2020, Journal of Biomolecular NMR.

Optimized NMR Experiments for the Isolation of I = ½ Manifold Transitions in Methyl Groups of Proteins.

G. Clore, V. Tugarinov, A. Ceccon, 2019, Chemphyschem : a European journal of chemical physics and physical chemistry.

High resolution measurement of methyl 13C(m)-13C and 1H(m)-13C(m) residual dipolar couplings in large proteins.

V. Tugarinov, Chenyun Guo, R. Godoy‐Ruiz, 2010, Journal of the American Chemical Society.

Line narrowing in methyl-TROSY using zero-quantum 1H-13C NMR spectroscopy.

L. Kay, V. Tugarinov, R. Sprangers, 2004, Journal of the American Chemical Society.

Decorrelating Kinetic and Relaxation Parameters in Exchange Saturation Transfer NMR: A Case Study of N-Terminal Huntingtin Peptides Binding to Unilamellar Lipid Vesicles.

G. Clore, V. Tugarinov, A. Ceccon, 2018, The journal of physical chemistry. B.

Magic-Angle-Pulse Driven Separation of Degenerate 1H Transitions in Methyl Groups of Proteins: Application to Studies of Methyl Axis Dynamics.

G. Clore, V. Tugarinov, T. Karamanos, 2020, Chemphyschem : a European journal of chemical physics and physical chemistry.

Estimates of methyl 13C and 1H CSA values (Δσ) in proteins from cross-correlated spin relaxation

L. Kay, R. Brüschweiler, V. Tugarinov, 2004, Journal of biomolecular NMR.

Separating degenerate (1)H transitions in methyl group probes for single-quantum (1)H-CPMG relaxation dispersion NMR spectroscopy.

L. Kay, V. Tugarinov, 2007, Journal of the American Chemical Society.

Probing side-chain dynamics in the proteasome by relaxation violated coherence transfer NMR spectroscopy.

L. Kay, V. Tugarinov, R. Sprangers, 2007, Journal of the American Chemical Society.

Addressing the overlap problem in the quantitative analysis of two dimensional NMR spectra: Application to 15N relaxation measurements

L. Kay, V. Tugarinov, E. Kupče, 2004, Journal of biomolecular NMR.

A methyl-TROSY based 13C relaxation dispersion NMR experiment for studies of chemical exchange in proteins

G. Clore, V. Tugarinov, J. Baber, 2023, Journal of Biomolecular NMR.

A "Steady-State" Relaxation Dispersion Nuclear Magnetic Resonance Experiment for Studies of Chemical Exchange in Degenerate 1H Transitions of Methyl Groups.

G. Clore, V. Tugarinov, Yusuke Okuno, 2022, The journal of physical chemistry letters.

Optimized selection of slow-relaxing 13C transitions in methyl groups of proteins: application to relaxation dispersion

G. Clore, V. Tugarinov, T. Karamanos, 2020, Journal of Biomolecular NMR.

Supplementary Information for Unraveling the structure and dynamics of the Human DNAJB 6 b chaperone by NMR reveals insights into Hsp 40-mediated proteostasis

G. Clore, V. Tugarinov, T. Karamanos, 2019 .

Abrogation of prenucleation, transient oligomerization of the Huntingtin exon 1 protein by human profilin I

G. Clore, R. Ghirlando, V. Tugarinov, 2020, Proceedings of the National Academy of Sciences.

A NMR experiment for simultaneous correlations of valine and leucine/isoleucine methyls with carbonyl chemical shifts in proteins

V. Tugarinov, V. Venditti, G. Marius Clore, 2014, Journal of biomolecular NMR.

Comparison of 13 CH 3 , 13 CH 2 D, and 13 CHD 2<

L. Kay, V. Tugarinov, Jason E. Ollerenshaw, 2005 .

Probing hydrogen bonds in the antibody-bound HIV-1 gp120 V3 loop by solid state NMR REDOR measurements

V. Tugarinov, J. Anglister, R. Tycko, 2000, Journal of biomolecular NMR.

High Molecular Weight Proteins and Protein Complexes: Structural Studies in Solution

V. Tugarinov, 2011 .

Probing the Rate-Limiting Step for Intramolecular Transfer of a Transcription Factor between Specific Sites on the Same DNA Molecule by 15Nz-Exchange NMR Spectroscopy

G. Clore, V. Tugarinov, K. Ryu, 2014, Journal of the American Chemical Society.

Structural analysis and catalytic activity of sol-gel-prepared Zn-Cr-O

V. Tugarinov, L. Forni, C. Oliva, 1993 .

Solution NMR evidence for symmetry in functionally or crystallographically asymmetric homodimers.

V. Tugarinov, R. Godoy-Ruiz, D. Gallagher, 2011, Journal of the American Chemical Society.

Kinetics of Fast Tetramerization of the Huntingtin Exon 1 Protein Probed by Concentration-Dependent On-Resonance R1ρ Measurements.

G. Clore, V. Tugarinov, A. Ceccon, 2020, The journal of physical chemistry letters.

Methyl-detected ‘out-and-back’ NMR experiments for simultaneous assignments of Alaβ and Ileγ2 methyl groups in large proteins

V. Tugarinov, D. Sheppard, Chenyun Guo, 2009, Journal of biomolecular NMR.

Global Dynamics and Exchange Kinetics of a Protein on the Surface of Nanoparticles Revealed by Relaxation-Based Solution NMR Spectroscopy.

A. Bax, V. Tugarinov, A. Ceccon, 2016, Journal of the American Chemical Society.