K. Saikatendu

发表

Nuclear Magnetic Resonance Structure of the N-Terminal Domain of Nonstructural Protein 3 from the Severe Acute Respiratory Syndrome Coronavirus

Margaret A. Johnson, K. Wüthrich, R. Stevens, 2007, Journal of Virology.

Progress towards a public chemogenomic set for protein kinases and a call for contributions

Stephen J. Capuzzi, T. Willson, Mathias Frederiksen, 2017, bioRxiv.

Severe acute respiratory syndrome coronavirus papain-like protease: structure of a viral deubiquitinating enzyme.

Raymond C Stevens, Kiira Ratia, Kumar Singh Saikatendu, 2006, Proceedings of the National Academy of Sciences of the United States of America.

Structural Basis of Severe Acute Respiratory Syndrome Coronavirus ADP-Ribose-1″-Phosphate Dephosphorylation by a Conserved Domain of nsP3

Kin Moy, Raymond C. Stevens, Peter Kuhn, 2005, Structure.

Report of the National Institutes of Health SARS-CoV-2 Antiviral Therapeutics Summit

Mindy I. Davis, D. Baker, D. Hazuda, 2021, The Journal of infectious diseases.

Proteomics Analysis Unravels the Functional Repertoire of Coronavirus Nonstructural Protein 3

Margaret A. Johnson, J. Yates, K. Wüthrich, 2008, Journal of Virology.

Crystal structure of MtnX phosphatase from Bacillus subtilis at 2.0 Å resolution provides a structural basis for bipartite phosphomonoester hydrolysis of 2‐hydroxy‐3‐keto‐5‐methylthiopentenyl‐1‐phosphate

Slawomir K. Grzechnik, Mitchell D. Miller, A. Godzik, 2007, Proteins.

The Kinase Chemogenomic Set (KCGS): An Open Science Resource for Kinase Vulnerability Identification

T. Willson, Mathias Frederiksen, S. Knapp, 2019, bioRxiv.

Functional proteomic and structural insights into molecular recognition in the nitrilase family enzymes.

R. Stevens, A. Olson, G. Morris, 2008, Biochemistry.

Nuclear Magnetic Resonance Structure Shows that the Severe Acute Respiratory Syndrome Coronavirus-Unique Domain Contains a Macrodomain Fold (cid:1)

Margaret A. Johnson, K. Wüthrich, P. Serrano, 2009 .

Crystal Structure of a Conserved Phosphatase Domain of Non-structural Protein-3 (nsp3) from the SARS Coronavirus

R. Stevens, J. Joseph, V. Subramanian, 2006 .

A fragment-based approach to identifying S-adenosyl-l-methionine -competitive inhibitors of catechol O-methyl transferase (COMT).

K. Saikatendu, Louise M. Walsh, G. Ambrus, 2014, Journal of medicinal chemistry.

Crystal structure and DNA binding of the homeodomain of the stem cell transcription factor Nanog.

Raymond C Stevens, Prasanna R Kolatkar, Ralf Jauch, 2008, Journal of molecular biology.

TP-064, a potent and selective small molecule inhibitor of PRMT4 for multiple myeloma

K. Saikatendu, C. Arrowsmith, M. Schapira, 2018, Oncotarget.

Ribonucleocapsid Formation of Severe Acute Respiratory Syndrome Coronavirus through Molecular Action of the N-Terminal Domain of N Protein

Raymond C. Stevens, Peter Kuhn, Kumar Singh Saikatendu, 2007, Journal of Virology.

Crystal Structure of Nonstructural Protein 10 from the Severe Acute Respiratory Syndrome Coronavirus Reveals a Novel Fold with Two Zinc-Binding Motifs

Kin Moy, Raymond C. Stevens, Peter Kuhn, 2006, Journal of Virology.

NMR Structure of the N-terminal Domain of the Nonstructural Protein 3 from the SARS Coronavirus

Margaret A. Johnson, K. Wüthrich, R. Stevens, 2007 .

Discovery of 7-Oxo-2,4,5,7-tetrahydro-6 H-pyrazolo[3,4- c]pyridine Derivatives as Potent, Orally Available, and Brain-Penetrating Receptor Interacting Protein 1 (RIP1) Kinase Inhibitors: Analysis of Structure-Kinetic Relationships.

M. Yoshikawa, K. Saikatendu, Y. Shimizu, 2018, Journal of medicinal chemistry.

Discovery of Potent, Selective, and Brain-Penetrant 1 H-Pyrazol-5-yl-1 H-pyrrolo[2,3- b]pyridines as Anaplastic Lymphoma Kinase (ALK) Inhibitors.

Tomoaki Hasui, M. Fushimi, K. Saikatendu, 2019, Journal of medicinal chemistry.

Crystal Structure of a Monomeric Form of Severe Acute Respiratory Syndrome Coronavirus Endonuclease nsp15 Suggests a Role for Hexamerization as an Allosteric Switch

Raymond C. Stevens, Peter Kuhn, Kumar Singh Saikatendu, 2007, Journal of Virology.

Identification of PARP14 inhibitors using novel methods for detecting auto-ribosylation.

K. Saikatendu, Tsuyoshi Ishii, T. Kawamoto, 2017, Biochemical and biophysical research communications.

Structure‐Based Design, Synthesis, and Biological Evaluation of Imidazo[4,5‐b]Pyridin‐2‐one‐Based p38 MAP Kinase Inhibitors: Part 2

K. Saikatendu, H. Sugimoto, Toshimasa Tanaka, 2019, ChemMedChem.

Nuclear Magnetic Resonance Structure Shows that the Severe Acute Respiratory Syndrome Coronavirus-Unique Domain Contains a Macrodomain Fold

Peter Kuhn, Margaret A. Johnson, K. Wüthrich, 2008, Journal of Virology.

Target 2035 – update on the quest for a probe for every protein

G. A. Bezerra, T. Willson, G. Superti-Furga, 2021, RSC medicinal chemistry.

Accelerating antiviral drug discovery: lessons from COVID-19

John A. Tallarico, Alpha A Lee, M. Hall, 2023, Nature Reviews Drug Discovery.

Target 2035 – an update on private sector contributions

T. Willson, S. Knapp, U. Lessel, 2023, RSC medicinal chemistry.

Open Science Discovery of Potent Non-Covalent SARS-CoV-2 Main Protease Inhibitors

David D. L. Minh, Vincent A. Voelz, Matthew F. D. Hurley, 2023, bioRxiv.

CACHE (Critical Assessment of Computational Hit-finding Experiments): A public–private partnership benchmarking initiative to enable the development of computational methods for hit-finding

Tudor I. Oprea, Rommie E. Amaro, Yoshua Bengio, 2021, Nature Reviews Chemistry.

Discovery of Novel and Highly Selective Cyclopropane ALK Inhibitors through a Fragment-Assisted, Structure-Based Drug Design

K. Saikatendu, Tsuyoshi Ishii, T. Wakabayashi, 2020, ACS omega.

Proteomics Analysis Unravels the Functional Repertoire of Coronavirus Nonstructural Protein 3

Margaret A. Johnson, J. Yates, K. Wüthrich, 2008, Journal of Virology.