H. Ochs

发表

The 2017 IUIS Phenotypic Classification for Primary Immunodeficiencies

J. Casanova, J. Franco, A. Bousfiha, 2017, Journal of Clinical Immunology.

The urgent need for integrated science to fight COVID-19 pandemic and beyond

Seeram Ramakrishna, Michael R. Hamblin, Lucina Q. Uddin, 2020, Journal of Translational Medicine.

DOCK8 Functions as an Adaptor that Links TLR–MyD88 Signaling to B Cell Activation

Schneider, Douglas R. McDonald, Ghassan, 2012 .

DOCK 8 functions as an adaptor that links Toll-like receptor – MyD 88 signaling to B cell activation

Douglas R. McDonald, L. Notarangelo, A. Plebani, 2012 .

An endothelial cell surface factor(s) induced in vitro by lipopolysaccharide, interleukin 1, and tumor necrosis factor-alpha increases neutrophil adherence by a CDw18-dependent mechanism.

H. Ochs, P. Beatty, K. Stanness, 1986, Journal of immunology.

Rituximab Inhibits the In Vivo Primary and Secondary Antibody Response to a Neoantigen, Bacteriophage phiX174

H. Ochs, M. Pescovitz, C. M. Bearden, 2005, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

Immune reconstitution in ADA-SCID after PBL gene therapy and discontinuation of enzyme replacement

L. Notarangelo, H. Ochs, A. Mortellaro, 2002, Nature Medicine.

Antibody responses to bacteriophage phi X174 in patients with adenosine deaminase deficiency.

R. Kobayashi, H. Ochs, M. Hershfield, 1992, Blood.

Effect of rituximab on human in vivo antibody immune responses.

H. Ochs, T. Torgerson, M. Pescovitz, 2011, The Journal of allergy and clinical immunology.

Hematopoietic Stem Cell Transplantation for X-Linked Thrombocytopenia With Mutations in the WAS gene

L. Notarangelo, T. Morio, H. Ochs, 2014, Journal of Clinical Immunology.

Dermatologic and immunologic findings in the immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome.

L. Goldsmith, H. Ochs, I. Kobayashi, 2004, Archives of dermatology.

Gains of glycosylation comprise an unexpectedly large group of pathogenic mutations

Guillaume Vogt, David N Cooper, Mehdi Mirsaeidi, 2005, Nature Genetics.

X-Linked Lymphoproliferative Disease 2b4 Molecules Displaying Inhibitory Rather than Activating Function Are Responsible for the Inability of Natural Killer Cells to Kill Epstein-Barr Virus–Infected Cells

L. Notarangelo, H. Ochs, S. Giliani, 2000 .

Partial V(D)J Recombination Activity Leads to Omenn Syndrome

Sandro Santagata, Paolo Vezzoni, Silvia Giliani, 1998, Cell.

Gastrointestinal manifestations of chronic granulomatous disease.

H. Ochs, M. Ament, 1973, The New England journal of medicine.

Identification of surface proteins mediating adherence of CD11/CD18-deficient lymphoblastoid cells to cultured human endothelium.

H. Ochs, E. Wayner, T. Carlos, 1990, The Journal of clinical investigation.

variants in antibody deficiency syndromes TNFRSF13B distinguishing disease-causing from risk-increasing mutations in TNFRSF13B Relevance of biallelic versus monoallelic

Anna L. David, A. Schäffer, E. Gertz, 2009 .

Relevance of biallelic versus monoallelic TNFRSF13B mutations in distinguishing disease-causing from risk-increasing TNFRSF13B variants in antibody deficiency syndromes.

A. Schäffer, E. Gertz, A. Plebani, 2008, Blood.

Structural basis for chromosome X-linked agammaglobulinemia: a tyrosine kinase disease.

J. Sowadski, D. Vetrie, M. Vihinen, 1994, Proceedings of the National Academy of Sciences of the United States of America.

Structural basis for pleckstrin homology domain mutations in X-linked agammaglobulinemia.

M. Zvelebil, M. Vihinen, H. Ochs, 1995, Biochemistry.

Wiskott-Aldrich syndrome.

L. Notarangelo, H. Ochs, C. Miao, 2002, Current opinion in hematology.

Ser ies The Wiskott-Aldrich Syndrome

H. Ochs, 2002 .

Wiskott-aldrich syndrome

H. Ochs, S. Nonoyama, H. D. Ochs, 2001, Current allergy and asthma reports.

Wiskott–Aldrich syndrome protein and platelets

H. Ochs, A. Oda, Hans D. Ochs, 2000, Immunological reviews.

Efficacy, Pharmacokinetics, Safety, and Tolerability of Flebogamma® 10% DIF, a High-Purity Human Intravenous Immunoglobulin, in Primary Immunodeficiency

H. Ochs, M. Stein, J. Moy, 2010, Journal of Clinical Immunology.

transfer of human factor VIII into hemophilia A mice Immunomodulation of transgene responses following naked DNA

H. Ochs, D. Rawlings, C. Miao, 2013 .

Immunomodulation of transgene responses following naked DNA transfer of human factor VIII into hemophilia A mice.

H. Ochs, D. Rawlings, C. Miao, 2005, Blood.

Physical and functional association of LFA-1 with DNAM-1 adhesion molecule.

H. Nakauchi, H. Ochs, L. Lanier, 1999, Immunity.

The Wiskott-Aldrich syndrome: studies of lymphocytes, granulocytes, and platelets.

H. Ochs, L. Harker, R. Clark, 1980, Blood.

FOXP3 forkhead domain mutation and regulatory T cells in the IPEX syndrome.

E. d'Hennezel, H. Ochs, T. Torgerson, 2009, The New England journal of medicine.

Successful use of the new immune-suppressor sirolimus in IPEX (immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome).

H. Ochs, O. Goulet, F. Ruemmele, 2005, The Journal of pediatrics.

Analysis of FOXP3 Reveals Multiple Domains Required for Its Function as a Transcriptional Repressor1

S. Ziegler, H. Ochs, T. Torgerson, 2006, The Journal of Immunology.

A Potential Screening Tool for IPEX Syndrome

H. Ochs, T. Torgerson, K. Sullivan, 2007, Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society.

Autoimmunity in common variable immunodeficiency: epidemiology, pathophysiology and management

H. Ochs, N. Rezaei, A. Aghamohammadi, 2017, Expert review of clinical immunology.

B cell activation via CD40 is required for specific antibody production by antigen-stimulated human B cells

H. Ochs, A. Aruffo, J. Ledbetter, 1993, The Journal of experimental medicine.

Stabilizers Used in Intravenous Immunoglobulin Products

H. Ochs, J. Siegel, Helene E. Young, 2010 .

Hepatitis C virus transmission by intravenous immunoglobulin.

P. Simmonds, H. Ochs, Lennart Hammarstrom, 1994, Journal of hepatology.

The mutational spectrum of human malignant autosomal recessive osteopetrosis.

A. Villa, M. Vihinen, L. Notarangelo, 2001, Human molecular genetics.

Combined immunodeficiencies with associated or syndromic features

H. Ochs, M. Lavin, Z. Chavoshzadeh, 2021 .

Common variable immunodeficiency as the initial presentation of dyskeratosis congenita.

H. Ochs, T. Torgerson, C. Bellodi, 2013, Journal of Allergy and Clinical Immunology.

Effect of therapeutic integrin (CD11a) blockade with efalizumab on immune responses to model antigens in humans: results of a randomized, single blind study.

H. Ochs, P. Patel, J. Krueger, 2008, The Journal of investigative dermatology.

Comèl-Netherton syndrome defined as primary immunodeficiency.

J. Orange, H. Ochs, T. Torgerson, 2009, The Journal of allergy and clinical immunology.

Flow Cytometry Contributions for the Diagnosis and Immunopathological Characterization of Primary Immunodeficiency Diseases With Immune Dysregulation

H. Ochs, R. Ramos, G. Segundo, 2019, Front. Immunol..

X-linked agammaglobulinemia. A clinical and molecular analysis.

H. Ochs, C. I. Smith, 1996, Medicine.

Functional analysis of peripheral blood B cells in patients with X-linked agammaglobulinemia.

T. Morio, H. Ochs, T. Yamadori, 1998, Journal of immunology.

Identification of FOXP3-negative regulatory T-like (CD4(+)CD25(+)CD127(low)) cells in patients with immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome.

H. Kanegane, H. Ochs, I. Kobayashi, 2011, Clinical immunology.

Common variable immunodeficiency (CVID): new genetic insight and unanswered questions

H. Ochs, Hans D. Ochs, 2014, Clinical and experimental immunology.

Primary Immune Deficiency Treatment Consortium (PIDTC) report.

M. van der Burg, L. Notarangelo, H. Bobby Gaspar, 2014, The Journal of allergy and clinical immunology.

Rapid tyrosine phosphorylation and activation of Bruton's tyrosine/Tec kinases in platelets induced by collagen binding or CD32 cross-linking.

H. Ochs, B. Druker, O. Witte, 2000, Blood.

CrkL is an adapter for Wiskott-Aldrich syndrome protein and Syk.

H. Ochs, S. Spencer, L. Lasky, 2001, Blood.

Bruton's tyrosine kinase is present in normal platelets and its absence identifies patients with X‐linked agammaglobulinaemia and carrier females

H. Ochs, Y. Baba, S. Tsukada, 2001 .

Btk/Tec kinases regulate sustained increases in intracellular Ca2+ following B‐cell receptor activation

H. Ochs, J. Kinet, A. Scharenberg, 1998, The EMBO journal.

thrombocytopenia Missense mutations of the WASP gene cause intermittent X-linked

L. Notarangelo, H. Ochs, S. Giliani, 2013 .

correlation effect on transcription, and translation and phenotype/genotype Mutations of the Wiskott-Aldrich Syndrome Protein (WASP): hotspots,

L. Notarangelo, H. Ochs, S. Giliani, 2011 .

Wiskott-Aldrich syndrome: diagnosis, clinical and laboratory manifestations, and treatment.

H. Ochs, P. Veys, A. Filipovich, 2009, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

Mutations of the Wiskott–Aldrich Syndrome Protein affect protein expression and dictate the clinical phenotypes

H. Ochs, 2009, Immunologic research.

The Wiskott-Aldrich syndrome.

L. Notarangelo, H. Ochs, A. Thrasher, 2006, The Journal of allergy and clinical immunology.

WASP and the phenotypic range associated with deficiency.

L. Notarangelo, H. Ochs, L. Notarangelo, 2005, Current opinion in allergy and clinical immunology.

X-linked immunodeficiencies

L. Notarangelo, H. Ochs, 2004, Current allergy and asthma reports.

Wiskott-Aldrich Syndrome: a model for defective actin reorganization, cell trafficking and synapse formation.

L. Notarangelo, H. Ochs, 2003, Current opinion in immunology.

Wiskott-Aldrich syndrome

L. Notarangelo, H. Ochs, C. Miao, 2008, Current opinion in hematology.

IPEX is a unique X-linked syndrome characterized by immune dysfunction, polyendocrinopathy, enteropathy, and a variety of autoimmune phenomena

H. Ochs, C. Bennett, 2001, Current opinion in pediatrics.

Wiskott-Aldrich syndrome/X-linked thrombocytopenia: WASP gene mutations, protein expression, and phenotype.

S. Kanner, H. Ochs, A. Aruffo, 1997, Blood.

Characterization of the Wiskott-Aldrich syndrome protein and its role in the disease.

H. Ochs, S. Nonoyama, H. D. Ochs, 1998, Current opinion in immunology.

X-linked lymphoproliferative syndrome. Natural history of the immunodeficiency.

H. Ochs, J. Sullivan, F. Brewster, 1983, The Journal of clinical investigation.

Primary immunodeficiency diseases : a molecular and genetic approach

H. Ochs, J. Puck, C. I. Smith, 2013 .

COPPER DEFICIENCY AND THE IMMUNE SYSTEM

H. Ochs, J. Sullivan, 1978, The Lancet.

Long–term hepatic adenovirus–mediated gene expression in mice following CTLA4Ig administration

A. Gown, P. Linsley, M. Kay, 1995, Nature Genetics.

Inhaled IFN-γ for persistent nontuberculous mycobacterial pulmonary disease due to functional IFN-γ deficiency

H. Ochs, W. Liles, T. Hallstrand, 2004, European Respiratory Journal.

Paracoccidioidomycosis Associated With a Heterozygous STAT4 Mutation and Impaired IFN-&ggr; Immunity

J. Casanova, H. Ochs, T. Torgerson, 2017, The Journal of infectious diseases.

Inhaled IFN-gamma for persistent nontuberculous mycobacterial pulmonary disease due to functional IFN-gamma deficiency.

H. Ochs, T. Hallstrand, W. Liles, 2004, The European respiratory journal.

H. Ochs, Sudhir Gupta, A N N Gardulf, 2006, Journal of Clinical Immunology.

All together to Fight COVID-19

L. Uddin, M. Perc, W. Al-Herz, 2020, The American Journal of Tropical Medicine and Hygiene.

Pathogen-specific humoral immunity and infections in BCMA-directed chimeric antigen receptor T-cell therapy recipients with multiple myeloma.

H. Ochs, S. Riddell, T. Stevens-Ayers, 2022, Transplantation and cellular therapy.

Specific immune-regulatory transcriptional signatures reveal sex and age differences in SARS-CoV-2 infected patients

I. Jurisica, N. Câmara, H. Ochs, 2020, medRxiv.

Carrier‐mediated enhancement of cognate T cell help: the basis for enhanced immunogenicity of meningococcal outer membrane protein polysaccharide conjugate vaccine

Samuel I. Miller, P. Linsley, H. Ochs, 2001, European Journal of Immunology.

The T-cell-dependent antibody response assay in nonclinical studies of pharmaceuticals and chemicals: study design, data analysis, interpretation.

H. Ochs, H. Lebrec, R. Wange, 2014, Regulatory toxicology and pharmacology : RTP.

Long-term interferon alpha maintenance therapy for chronic hepatitis C infection in a patient with common variable immune deficiency.

H. Ochs, R. Willson, S. Fischer, 1999, Journal of clinical gastroenterology.

Rapid Multiplexed Proteomic Screening for Primary Immunodeficiency Disorders From Dried Blood Spots

Jeffrey R. Whiteaker, A. Paulovich, H. Ochs, 2018, Front. Immunol..

Current Perspectives and Unmet Needs of Primary Immunodeficiency Care in Asia Pacific

H. Kanegane, H. Ochs, Y. Lau, 2020, Frontiers in Immunology.

A high frequency of distinct ATM gene mutations in ataxia-telangiectasia.

H. Ochs, R. Gatti, S. Teraoka, 1996, American journal of human genetics.

X-Linked Lymphoproliferative Disease

L. Notarangelo, H. Ochs, S. Giliani, 2000, The Journal of experimental medicine.

CTLA4Ig-mediated blockade of T-cell costimulation in patients with psoriasis vulgaris.

M. Lebwohl, P. Linsley, H. Ochs, 1999, The Journal of clinical investigation.

Combined Immunodeficiencies With Syndromic Features

H. Ochs, 2021, Reference Module in Biomedical Sciences.

The International Union of Immunological Societies (IUIS) Primary Immunodeficiency Diseases (PID) Classification Committee

A. Fischer, J. Casanova, L. Notarangelo, 2008 .

Neutrophil adhesion in leukocyte adhesion deficiency syndrome type 2.

H. Ochs, J. Paulson, R. Bayer, 1995, The Journal of clinical investigation.

Effector Cytokine Expression Expression in T Cells Thereby Limiting FOXP3 Inhibits Activation-Induced NFAT2

H. Ochs, T. Torgerson, I. Dozmorov, 2009 .

A Short Burst of Oral Corticosteroid for Children with Acute Asthma: Is There an Impact on Immunity?

H. Ochs, F. Ducharme, B. Mazer, 2010 .

The network interplay of type 1 interferon and toll-like receptor signaling cascades hallmarks the immune response against Candida spp. infections

I. Jurisica, H. Ochs, N. Câmara, 2021 .

Monoclonal antibody-defined functional epitopes on the adhesion-promoting glycoprotein complex (CDw18) of human neutrophils.

H. Ochs, C. June, P. Beatty, 1986, Blood.

Lentiviral and murine retroviral transduction of T cells for expression of human CD40 ligand.

H. Ochs, J. Seppen, J. Garcia, 2000, Human gene therapy.

Ocular Involvement in Primary Immunodeficiency Diseases

H. Ochs, N. Rezaei, A. Aghamohammadi, 2013, Journal of Clinical Immunology.

The co‐occurrence of Wilson disease and X‐linked agammaglobulinemia in one family highlights the promising diagnostic potential of proteolytic analysis

H. Ochs, T. Torgerson, C. Myers, 2020, Molecular genetics & genomic medicine.

The antibody response to bacteriophage is linked to the lymphopenia gene in congenic BioBreeding rats.

Å. Lernmark, H. Ochs, C. Greenbaum, 2002, FEMS immunology and medical microbiology.

Immunologic responses to bacteriophage phi-X 174 in immunodeficiency diseases.

H. Ochs, R. Wedgwood, S. Davis, 1971, The Journal of clinical investigation.

Defect in neutrophil granulocyte chemotaxis in Job's syndrome of recurrent "cold" staphylococcal abscesses.

H. Ochs, H. Pabst, H. Hill, 1974, Lancet.

Severe recurrent bacterial infections associated with defective adherence and chemotaxis in two patients with neutrophils deficient in a cell-associated glycoprotein.

H. Ochs, D. Brautigan, T. Price, 1982, The Journal of pediatrics.

STRUCTURE AND FUNCTION OF THE GASTROINTESTINAL TRACT IN PRIMARY IMMUNODEFICIENCY SYNDROMES A STUDY OF 39 PATIENTS

H. Ochs, M. Ament, S. Davis, 1973, Medicine.

Oligoclonality, impaired class switch and B-cell memory responses in WHIM syndrome.

C. Cunningham-Rundles, H. Ochs, G. Diaz, 2010, Clinical immunology.

Immune deficiency in SCID mice.

H. Ochs, S. Nonoyama, 1996, International reviews of immunology.

The SCID mouse, a model for human diseases.

H. Ochs, S. Nonoyama, F. Smith, 1990 .

Genetic analysis of C4 deficiency.

H. Ochs, C. Alper, Z. Awdeh, 1981, The Journal of clinical investigation.

Wiskott-Aldrich syndrome protein is required for regulatory T cell homeostasis.

S. Ziegler, H. Ochs, T. Torgerson, 2007, The Journal of clinical investigation.

Primary Immune Deficiency Disorders Presenting as Autoimmune Diseases: IPEX and APECED

H. Ochs, T. Torgerson, B. Costa-Carvalho, 2008, Journal of Clinical Immunology.

Quantitative analysis of tissue inflammation and responses to treatment in immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome, and review of literature.

H. Ochs, Y. Chiou, C. Shieh, 2016, Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi.

CD4+FOXP3+ regulatory T cells confer long-term regulation of factor VIII-specific immune responses in plasmid-mediated gene therapy-treated hemophilia mice.

S. Ziegler, H. Ochs, T. Torgerson, 2009, Blood.

The Role of CD40 and its Ligand in the Regulation of the Immune Response

H. Ochs, A. Aruffo, J. Ledbetter, 1994, Immunological Reviews.

Strain-dependent leakiness of mice with severe combined immune deficiency.

I. Bernstein, H. Ochs, S. Nonoyama, 1993, Journal of immunology.

The half-lives of IgG subclasses and specific antibodies in patients with primary immunodeficiency who are receiving intravenously administered immunoglobulin.

H. Ochs, M. Lee, K. Pyun, 1988, The Journal of laboratory and clinical medicine.

Absence of IgD-CD27(+) memory B cell population in X-linked hyper-IgM syndrome.

H. Ochs, A. Komiyama, S. Nonoyama, 1998, The Journal of clinical investigation.

Costimulation through CD28 enhances T cell-dependent B cell activation via CD40-CD40L interaction.

H. Ochs, E. Clark, W. Fanslow, 1994, Journal of immunology.

Immunodeficiencies

L. Notarangelo, J. Franco, C. Cunningham-Rundles, 2009, Clinical and experimental immunology.

Common Variable Immune Deficiency Overview

H. Ochs, T. Torgerson, A. Scharenberg, 2006 .

Restricted immunoglobulin constant heavy G chain genes in primary immunodeficiencies.

H. Ochs, L. Hammarström, V. Oxelius, 2008, Clinical immunology.

Diagnosis and clinical management of Wiskott–Aldrich syndrome: current and emerging techniques

H. Ochs, D. Buchbinder, Corey Cavannaugh, 2022, Expert review of clinical immunology.

Hematopoietic Stem Cell Therapy for Wiskott–Aldrich Syndrome: Improved Outcome and Quality of Life

H. Ochs, A. Petrovič, K. Mallhi, 2021, Journal of blood medicine.

Clinical spectrum, pathophysiology and treatment of the Wiskott–Aldrich syndrome

L. Notarangelo, H. Ochs, M. Albert, 2011, Current opinion in hematology.

Wiskott-Aldrich Syndrome Protein Is Required for Homeostasis and Function of Invariant NKT Cells1

H. Ochs, D. Rawlings, A. Astrakhan, 2009, The Journal of Immunology.

Invariant NKT Cells Required for Homeostasis and Function of Wiskott-Aldrich Syndrome Protein Is

H. Ochs, D. Rawlings, A. Astrakhan, 2009 .

The Wiskott-Aldrich Syndrome Protein Regulates Nuclear Translocation of NFAT2 and NF-κB (RelA) Independently of Its Role in Filamentous Actin Polymerization and Actin Cytoskeletal Rearrangement1

H. Ochs, Y. Vyas, B. DuPont, 2005, The Journal of Immunology.

When is umbilical cord separation delayed?

H. Ochs, C. Wilson, J. Almquist, 1985, The Journal of pediatrics.

Diminished expression of CD40 ligand by activated neonatal T cells.

H. Ochs, D. Lewis, A. Aruffo, 1995, The Journal of clinical investigation.

Home-Based Subcutaneous Immunoglobulin Versus Hospital-Based Intravenous Immunoglobulin in Treatment of Primary Antibody Deficiencies: Systematic Review and Meta Analysis

H. Ochs, N. Rezaei, A. Aghamohammadi, 2012, Journal of Clinical Immunology.

Heterozygous signal transducer and activator of transcription 3 mutations in hyper-IgE syndrome result in altered B-cell maturation.

H. Ochs, T. Torgerson, D. Rawlings, 2012, The Journal of allergy and clinical immunology.

Transient immunomodulation with anti-CD40 ligand antibody and CTLA4Ig enhances persistence and secondary adenovirus-mediated gene transfer into mouse liver.

A. Gown, P. Linsley, M. Kay, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Deletion within the Src homology domain 3 of Bruton's tyrosine kinase resulting in X-linked agammaglobulinemia (XLA)

M. Vihinen, H. Ochs, O. Witte, 1994, Journal of Experimental Medicine.

Immune dysregulation, polyendocrinopathy, enteropathy, X-linked (IPEX) syndrome: A systematic review.

Joon Suk Lee, H. Ochs, M. Eisenhut, 2020, Autoimmunity reviews.

Reduced expression of FOXP3 and regulatory T-cell function in severe forms of early-onset autoimmune enteropathy.

F. Rieux-Laucat, A. Fischer, J. Casanova, 2010, Gastroenterology.

Developmental changes of FOXP3-expressing CD4+CD25+ regulatory T cells and their impairment in patients with FOXP3 gene mutations.

H. Kanegane, H. Ochs, A. Banham, 2007, Clinical immunology.

This information is current as Transcriptional Repressor Required for Its Function as a Analysis of FOXP 3 Reveals Multiple Domains and

S. Ziegler, H. Ochs, T. Torgerson, 2006 .

Suppression by human FOXP3+ regulatory T cells requires FOXP3-TIP60 interactions

E. d'Hennezel, B. Li, H. Ochs, 2017, Science Immunology.

Does graft-versus-host disease influence the tempo of immunologic recovery after allogeneic human marrow transplantation? An observation on 56 long-term survivors.

H. Ochs, R. Storb, K. Atkinson, 1978, Blood.

STUDIES OF IMMUNOLOGICAL REACTIVITY FOLLOWING SYNGENEIC OR ALLOGENEIC MARROW GRAFTS IN MAN

H. Ochs, R. Storb, E. Thomas, 1973, Transplantation.

BTKbase, mutation database for X-linked agammaglobulinemia (XLA).

M. Vihinen, H. Ochs, J. Ollila, 1996, Nucleic acids research.

Bone marrow transplantation in the Wiskott-Aldrich syndrome. Complete hematological and immunological reconstitution.

H. Ochs, R. Storb, L. Lum, 1982, Transplantation.

Subcutaneous immunoglobulin: opportunities and outlook

H. Ochs, M. Sturzenegger, R. Shapiro, 2009, Clinical and experimental immunology.

thrombocytopenia band Xp11-12: further evidence of genetic heterogeneity of X-linked Mapping of a syndrome of X-linked thrombocytopenia with thalassemia to

K. Niakan, H. Ochs, W. Raskind, 2013 .

The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3

H. Ochs, P. Ferguson, F. Ramsdell, 2001, Nature Genetics.

Immune dysregulation, polyendocrinopathy, enteropathy, X-linked inheritance: model for autoaggression.

H. Ochs, T. Torgerson, 2007, Advances in experimental medicine and biology.

Novel mutations of FOXP3 in two Japanese patients with immune dysregulation, polyendocrinopathy, enteropathy, X linked syndrome (IPEX)

H. Ochs, M. Yamada, I. Kobayashi, 2001, Journal of medical genetics.

Two Unique Cases of X-linked SCID: A Diagnostic Challenge in the Era of Newborn Screening

L. Notarangelo, J. Walter, H. Ochs, 2019, Front. Pediatr..

Severe systemic lupus erythematosus with nephritis in a boy with deficiency of the fourth component of complement.

H. Ochs, J. Leddy, J. Schaller, 1977, Arthritis and rheumatism.

Molecular biology of the Wiskott-Aldrich syndrome.

H. Ochs, R. Rengan, 2000, Reviews in immunogenetics.

Linkage between the gene (or genes) controlling synthesis of the fourth component of complement and the major histocompatibility complex.

H. Ochs, J. Hansen, B. Dupont, 1977, The New England journal of medicine.

Indications and safety of intravenous and subcutaneous immunoglobulin therapy

H. Ochs, N. Rezaei, A. Aghamohammadi, 2011, Expert review of clinical immunology.

Single-cell analysis of normal and FOXP 3-mutant human T cells : FOXP 3 expression without regulatory T cell development

A. Rudensky, H. Ochs, T. Torgerson, 2006 .

Pharmacokinetics and tolerability of a new intravenous immunoglobulin preparation, IGIV‐C, 10% (Gamunex™, 10%)

C. Cunningham-Rundles, H. Ochs, M. Sweetser, 2003 .

IgM deficiency: clinical spectrum and immunologic assessment.

H. Ochs, M. Guill, K. Pyun, 1989, Annals of allergy.

Progressive specific immune attrition after primary, secondary and tertiary immunizations with bacteriophage ΦX174 in asymptomatic HIV-1 infected patients

H. Ochs, A. Rubinstein, J. Shliozberg, 2000, AIDS.

Mutations of the CD40 ligand gene and its effect on CD40 ligand expression in patients with X-linked hyper IgM syndrome.

H. Ochs, A. Aruffo, H. Pabst, 1998, Blood.

Antibody responses to bacteriophage phi X174 in patients with adenosine deaminase deficiency.

R. Kobayashi, H. Ochs, M. Hershfield, 1992, Blood.

Immunological recovery in 48 patients following syngeneic marrow transplantation or hematological malignancy.

H. Deeg, H. Ochs, K. Sullivan, 1982, Transplantation.

The recognition and classification of immunodeficiency diseases with bacteriophage phiChi 174.

H. Ochs, R. Wedgwood, S. Davis, 1975, Birth defects original article series.

Genetic deficiency of C4, C2 or C1q and lupus syndromes. Association with anti-Ro (SS-A) antibodies.

H. Ochs, G. Hauptmann, G. Tappeiner, 1985, Clinical and experimental immunology.

Immunomodulatory Effects of Mixed Hematopoietic Chimerism: Immune Tolerance in Canine Model of Lung Transplantation

R. Glenny, S. Ziegler, H. Ochs, 2009, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

Rubella Virus-Associated Cutaneous Granulomatous Disease: a Unique Complication in Immune-Deficient Patients, Not Limited to DNA Repair Disorders

C. Bodemer, C. Klein, H. Ochs, 2019, Journal of Clinical Immunology.

Corrigendum: Primary Immunodeficiency Diseases: An Update on the Classification from the International Union of Immunological Societies Expert Committee for Primary Immunodeficiency

J. Casanova, J. Franco, A. Bousfiha, 2014, Front. Immunol..

Specific antibody production to a recall or a neoantigen by SCID mice reconstituted with human peripheral blood lymphocytes.

H. Ochs, S. Nonoyama, F. Smith, 1993, Journal of immunology.

Dendritic cells from X-linked hyper-IgM patients present impaired responses to Candida albicans and Paracoccidioides brasiliensis.

H. Ochs, T. Torgerson, M. Hackett, 2012, The Journal of allergy and clinical immunology.

X-Linked Agammaglobulinemia: Report on a United States Registry of 201 Patients

C. Cunningham-Rundles, H. Ochs, K. Sullivan, 2006, Medicine.

FBP17 Mediates a Common Molecular Step in the Formation of Podosomes and Phagocytic Cups in Macrophages*

S. Tsuboi, H. Ochs, H. Takada, 2009, Journal of Biological Chemistry.

Specific cloning of DNA fragments absent from the DNA of a male patient with an X chromosome deletion.

A. Monaco, S. Latt, W. Middlesworth, 1985, Proceedings of the National Academy of Sciences of the United States of America.

Primary immunodeficiency: looking backwards, looking forwards.

C. Cunningham-Rundles, H. Ochs, W. Shearer, 2004, The Journal of allergy and clinical immunology.

The Wiskott-Aldrich syndrome protein

H. Ochs, A. Aruffo, R. Blaese, 1996 .

Human antibody responses to bacteriophage phi X 174: sequential induction of IgM and IgG subclass antibody.

H. Ochs, K. Pyun, R. Wedgwood, 1989, Clinical immunology and immunopathology.

A Novel Gain-of-Function IKBA Mutation Underlies Ectodermal Dysplasia with Immunodeficiency and Polyendocrinopathy

T. Hökfelt, J. Casanova, C. Picard, 2013, Journal of Clinical Immunology.

Interleukin receptor-associated kinase (IRAK-4) deficiency associated with bacterial infections and failure to sustain antibody responses.

J. Casanova, C. Picard, H. Ochs, 2004, The Journal of pediatrics.

Absence of IgD 2 CD 27 1 Memory B Cell Population in X-linked Hyper-IgM Syndrome

H. Ochs, A. Komiyama, S. Nonoyama, 1998 .

Defective antigen-induced lymphocyte proliferation in the X-linked hyper-IgM syndrome.

H. Ochs, K. Sullivan, J. Winkelstein, 1997, The Journal of pediatrics.

The random inactivation of the X chromosome carrying the defective gene responsible for X-linked hyper IgM syndrome (X-HIM) in female carriers of HIGM1.

H. Ochs, A. Aruffo, J. Ledbetter, 1994, The Journal of clinical investigation.

Use of intravenous gamma-globulin in antibody immunodeficiency: results of a multicenter controlled trial.

H. Ochs, A. Ammann, D. Wara, 1982, Clinical immunology and immunopathology.

CTLA 4 Ig-mediated blockade of T-cell costimulation in patients with psoriasis vulgaris

M. Lebwohl, P. Linsley, H. Ochs, 1999 .

Retroviral-mediated gene transfer of the leukocyte integrin CD18 into peripheral blood CD34+ cells derived from a patient with leukocyte adhesion deficiency type 1.

H. Ochs, W. Liles, D. Hickstein, 1998, Blood.

A monoclonal antibody-defined membrane antigen complex is required for neutrophil-neutrophil aggregation.

H. Ochs, P. Beatty, J. Harlan, 1985, Blood.

The Wiskott-Aldrich syndrome and X-linked congenital thrombocytopenia are caused by mutations of the same gene.

U. Francke, J. Derry, H. Ochs, 1995, Blood.

WASP gene mutations in Wiskott-Aldrich syndrome and X-linked thrombocytopenia.

X. Estivill, U. Francke, J. Derry, 1995, Human molecular genetics.

Human CD40 ligand deficiency dysregulates the macrophage transcriptome causing functional defects that are improved by exogenous IFN‐&ggr;

L. Notarangelo, H. Ochs, T. Torgerson, 2017, The Journal of allergy and clinical immunology.

Potentiation of TLR9 responses for human naïve B-cell growth through RP105 signaling.

H. Ochs, K. Miyake, Takuma Hayashi, 2010, Clinical immunology.

Unimpaired Activation of c-Jun NH2-Terminal Kinase (JNK) 1 upon CD40 Stimulation in B Cells of Patients with X-Linked Agammaglobulinemia

H. Ochs, V. Schuster, C. Brunner, 2002, Journal of Clinical Immunology.

Rapid molecular analysis of the STAT3 gene in Job syndrome of hyper-IgE and recurrent infectious diseases.

M. Leppert, H. Ochs, J. Carey, 2010, The Journal of molecular diagnostics : JMD.

In vitro studies of the hyper-IgE disorders: suppression of spontaneous IgE synthesis by allogeneic suppressor T lymphocytes.

H. Ochs, R. Wedgwood, M. J. Kraemer, 1982, Clinical immunology and immunopathology.

Bispecific monoclonal antibody complexes facilitate erythrocyte binding and liver clearance of a prototype particulate pathogen in a monkey model.

H. Ochs, M. Craig, R. Taylor, 1997, Journal of immunology.

Treatment of established human graft-versus-host disease by antithymocyte globulin.

P. Neiman, H. Ochs, R. Storb, 1974, Blood.

Immunologic reconstitution during PEG-ADA therapy in an unusual mosaic ADA deficient patient.

H. Ochs, T. Torgerson, A. Scharenberg, 2009, Clinical immunology.

Autosomal Dominant Hyper-IgE Syndrome in the USIDNET Registry.

C. Cunningham-Rundles, S. Holland, H. Ochs, 2017, The journal of allergy and clinical immunology. In practice.

Genetic linkage of hyper-IgE syndrome to chromosome 4.

A. Schäffer, S. Holland, H. Ochs, 1999, American journal of human genetics.

All together to Fight Novel Coronavirus Disease (COVID-19).

L. Uddin, M. Perc, W. Al-Herz, 2020, The American journal of tropical medicine and hygiene.

CD40 ligand expression is defective in a subset of patients with common variable immunodeficiency.

H. Ochs, A. Aruffo, J. Ledbetter, 1994, Proceedings of the National Academy of Sciences of the United States of America.

Long-term low-dose IL-2 enhances immune function in common variable immunodeficiency.

C. Cunningham-Rundles, H. Ochs, C. Bodian, 2001, Clinical immunology.

Parvovirus B19-induced anemia as the presenting manifestation of X-linked hyper-IgM syndrome.

R. Kobayashi, H. Ochs, H. Hasle, 1998, The Journal of infectious diseases.

Mutations of the CD40 LigandGene and Its Effect on CD40 Ligand Expression in Patients With X-Linked Hyper IgM Syndrome

H. Ochs, A. Aruffo, H. Pabst, 1998 .

Mutations of the CD 40 Ligand Gene and Its Effect on CD 40 Ligand Expression in Patients With X-Linked Hyper IgM Syndrome

H. Ochs, A. Aruffo, H. Pabst, 1998 .

The role of CD40L (gp39)/CD40 in T/B cell interaction and primary immunodeficiency.

H. Ochs, A. Aruffo, D. Hollenbaugh, 1994, Seminars in immunology.

Agammaglobulinemia: comorbidities and long-term therapeutic risks

H. Ochs, N. Rezaei, A. Aghamohammadi, 2017 .

Detection of X-linked lymphoproliferative disease using molecular and immunovirologic markers.

H. Ochs, D. Purtilo, H. Grierson, 1989, The American journal of medicine.

Origin of mutations in two families with X-linked chronic granulomatous disease.

A. Swaroop, U. Francke, H. Ochs, 1990, Blood.

Normal immunologic response to a neoantigen, bacteriophage phiX-174, in baboons with long-term lymphohematopoietic reconstitution from highly purified CD34+ Lin- allogeneic marrow cells.

I. Bernstein, H. Ochs, E. Bryant, 1997, Blood.

Immunologic Reactivity in Canine Marrow Graft Recipients

H. Ochs, R. Storb, E. Thomas, 1974, The Journal of Immunology.

Abnormal primary antibody responses in pediatric trauma patients.

H. Ochs, B. Peterson, N. Wilson, 1989, The Journal of pediatrics.

WAVE/Scars in platelets.

H. Ochs, D. Yamazaki, T. Takenawa, 2005, Blood.

Self-infusion of intravenous immunoglobulin by immunodeficient patients at home.

H. Ochs, M. Lee, R. Wedgwood, 1987, The Journal of infectious diseases.

From clinical observations and molecular dissection to novel therapeutic strategies for primary immunodeficiency disorders

H. Ochs, D. Petroni, 2018, American journal of medical genetics. Part A.

Flow cytometry-based diagnosis of primary immunodeficiency diseases.

H. Kanegane, T. Morio, H. Ochs, 2018, Allergology international : official journal of the Japanese Society of Allergology.

Flow cytometry-based diagnosis of primary immunode fi ciency diseases

H. Kanegane, T. Morio, H. Ochs, 2017 .

Subcutaneous Immunoglobulin Replacement Therapy with Hizentra® is Safe and Effective in Children Less Than 5 Years of Age

H. Ochs, E. Haddad, N. Patel, 2015, Journal of Clinical Immunology.

Controversies in IgG replacement therapy in patients with antibody deficiency diseases.

H. Ochs, E. Gelfand, W. Shearer, 2013, The Journal of allergy and clinical immunology.

Suppression of human immunoglobulin E antibody production by a new naphthalene derivative.

H. Ochs, K. Takahashi, K. Komoriya, 1995, Immunopharmacology.

Long‐term outcomes of 176 patients with X‐linked hyper‐IgM syndrome treated with or without hematopoietic cell transplantation

L. Notarangelo, J. Chou, C. Cunningham-Rundles, 2017, The Journal of allergy and clinical immunology.

The pharmacokinetics of total IgG, IgG subclasses, and type specific antibodies in immunodeficient patients.

H. Ochs, M. Lee, R. Wedgwood, 1991, Immunological investigations.

Comparison of high-dose and low-dose intravenous immunoglobulin therapy in patients with primary immunodeficiency diseases.

H. Ochs, A. Ammann, D. Wara, 1984, The American journal of medicine.

Distinct interactions of the X-linked lymphoproliferative syndrome gene product SAP with cytoplasmic domains of members of the CD2 receptor family.

L. Notarangelo, H. Ochs, C. Duckett, 2001, Clinical immunology.

homeostasis and function populations and serves a unique role in marginal zone B-cell WASP confers selective advantage for specific hematopoietic cell

L. Notarangelo, H. Ochs, S. Snapper, 2013 .

WASP confers selective advantage for specific hematopoietic cell populations and serves a unique role in marginal zone B-cell homeostasis and function.

L. Notarangelo, H. Ochs, S. Snapper, 2008, Blood.

Diminished expression of CD40 ligand may contribute to the defective humoral immunity in patients with MHC class II deficiency

H. Ochs, D. Lewis, A. Aruffo, 1998, European journal of immunology.

Iron Deficiency in the Rat: Effects on Neutrophil Activation and Metabolism

H. Ochs, R. Person, B. Mackler, 1984, Pediatric Research.

Differentiation of lymphocyte function in vivo following transplantation of thymic epithelial monolayers.

H. Ochs, C. Handorf, H. Herrod, 1981, Clinical immunology and immunopathology.

Anti-CD3 antibodies modulate anti-factor VIII immune responses in hemophilia A mice after factor VIII plasmid-mediated gene therapy.

H. Ochs, D. Rawlings, C. Miao, 2009, Blood.

Serum Gm allotype levels in common variable immunodeficiency: preponderance of homozygous G2m(",") on IGHCG2.

H. Ochs, V. Oxelius, 1996, Experimental and clinical immunogenetics.

Neutralization of different echovirus serotypes by individual lots of intravenous immunoglobulin

H. Ochs, M. Farcet, T. Kreil, 2011, Journal of medical virology.

Characterization of B-cell lines established from two X-linked severe combined immunodeficiency patients: interleukin-15 binds to the B cells but is not internalized efficiently.

H. Ochs, K. Sugamura, K. Schooley, 1995, Blood.

Echovirus encephalitis/myositis in X-linked agammaglobulinemia.

H. Ochs, L. Corey, R. Wedgwood, 1985, The New England journal of medicine.

Successful treatment of echovirus meningoencephalitis and myositis-fasciitis with intravenous immune globulin therapy in a patient with X-linked agammaglobulinemia.

H. Ochs, P. Mease, R. Wedgwood, 1981, The New England journal of medicine.

Effect of antibodies directed against complement receptors on phagocytosis by polymorphonuclear leukocytes: use of iodination as a convenient measure of phagocytosis.

R. Schreiber, H. Ochs, P. Beatty, 1985, Journal of immunology.

Partial immune reconstitution of X-linked hyper IgM syndrome with recombinant CD40 ligand.

S. Pittaluga, H. Ochs, S. Migueles, 2011, Blood.

WIP is a chaperone for Wiskott–Aldrich syndrome protein (WASP)

K. Siminovitch, R. Geha, H. Ochs, 2007, Proceedings of the National Academy of Sciences.

Comparison of Common Monogenic Defects in a Large Predominantly Antibody Deficiency Cohort.

V. Lougaris, A. Plebani, H. Ochs, 2019, The journal of allergy and clinical immunology. In practice.

Targeting FcRn for immunomodulation: Benefits, risks, and practical considerations

C. Cunningham-Rundles, H. Ochs, D. Vinh, 2020, Journal of Allergy and Clinical Immunology.

Unique mutations of Bruton's tyrosine kinase in fourteen unrelated X-linked agammaglobulinemia families.

H. Ochs, J. Winkelstein, S. Chen, 1994, Human Molecular Genetics.

The role of neutrophil membrane glycoprotein 150 (Gp-150) in neutrophil-mediated endothelial cell injury in vitro.

H. Ochs, P. Beatty, J. Harlan, 1985, Journal of immunology.

Excellent Outcomes Following Hematopoietic Cell Transplantation for Wiskott-Aldrich Syndrome: A PIDTC Report.

L. Notarangelo, H. Ochs, J. Puck, 2020, Blood.

Hyper IgE syndromes: clinical and molecular characteristics

H. Ochs, T. Al-Shaikhly, 2018, Immunology and cell biology.

Immunoglobulin Replacement Therapy: Past, Present, Future

H. Ochs, 2015 .

Immunity: From Serendipitous Observations to Science-Based Specialty

H. Ochs, 2014 .

Activated B cells from patients with common variable immunodeficiency proliferate and synthesize immunoglobulin.

H. Ochs, M. Howard, H. Ishida, 1993, The Journal of clinical investigation.

Second attacks of pneumonia due to Mycoplasma pneumoniae.

H. Ochs, G. Kenny, H. Foy, 1977, The Journal of infectious diseases.

Human monocyte adherence to cultured vascular endothelium: monoclonal antibody-defined mechanisms.

H. Ochs, P. Beatty, J. Harlan, 1985, Journal of immunology.

CD40 ligand deficiency: treatment strategies and novel therapeutic perspectives

H. Ochs, B. Al-Ramadi, A. Condino-Neto, 2019, Expert review of clinical immunology.

Iron deficiency in the rat

H. Ochs, R. Person, B. Mackler, 1984 .

Ubiquitous high-level gene expression in hematopoietic lineages provides effective lentiviral gene therapy of murine Wiskott-Aldrich syndrome.

H. Ochs, B. Ryu, D. Rawlings, 2012, Blood.

The Wiskott-Aldrich Syndrome Protein Regulates Nuclear Translocation of NFAT2 and NF-κB (RelA) Independently of Its Role in Filamentous Actin Polymerization and Actin Cytoskeletal Rearrangement

H. Ochs, Y. Vyas, B. DuPont, 2005, The Journal of Immunology.

Cholangiopathy and tumors of the pancreas, liver, and biliary tree in boys with X-linked immunodeficiency with hyper-IgM.

L. Notarangelo, H. Ochs, J. Bonnefoy, 1997, Journal of immunology.

Combined De-Novo Mutation and Non-Random X-Chromosome Inactivation Causing Wiskott-Aldrich Syndrome in a Female with Thrombocytopenia

S. Scherer, H. Ochs, T. Torgerson, 2013, Journal of Clinical Immunology.

Long-term outcome and lineage-specific chimerism in 194 patients with Wiskott-Aldrich syndrome treated by hematopoietic cell transplantation in the period 1980-2009: an international collaborative study.

A. Fischer, A. Schulz, W. Friedrich, 2011, Blood.

Long-term outcome and lineage-speciﬁc chimerism in 194 patients with Wiskott-Aldrich syndrome treated by hematopoietic cell transplantation in the period 1980-2009: an international collaborative study

A. Fischer, A. Schulz, W. Friedrich, 2011 .

Immunologic, toxicologic and marrow transplantation studies in dogs given dimethyl myleran.

H. Ochs, R. Storb, E. Thomas, 1974, Biomedicine / [publiee pour l'A.A.I.C.I.G.].

Thymus transplantation after allogeneic bone marrow graft to prevent chronic graft-versus-host disease in humans.

H. Ochs, K. Sullivan, R. Storb, 1982, Transplantation.

Primary Immunodeficiency Diseases Associated with Neurologic Manifestations

H. Ochs, N. Rezaei, A. Aghamohammadi, 2012, Journal of Clinical Immunology.

Soluble molecules in intravenous immunoglobulin: benefits and limitations

H. Ochs, N. Rezaei, A. Aghamohammadi, 2016, Expert review of clinical immunology.

A Novel Homozygous JAK3 Mutation Leading to T-B+NK– SCID in Two Brazilian Patients

H. Ochs, T. Torgerson, G. Segundo, 2018, Front. Pediatr..

Mutations of the CD40 ligand gene in 13 Japanese patients with X-linked hyper-IgM syndrome

H. Ochs, S. Nonoyama, H. Nunoi, 1997, Human Genetics.

Evaluation of CD 4 + T Cell Function In Vivo in HIV-Infected Patients as Measured by Bacteriophage phiX 174 Immunization

H. Ochs, H. Lane, M. Feinberg, 2022 .

An emerging era of clinical benefit from gene therapy.

H. Ochs, H. Malech, 2015, JAMA.

IMMUNOLOGIC RECOVERY IN HUMAN MARROW GRAFT RECIPIENTS GIVEN CYCLOSPORINE OR METHOTREXATE FOR THE PREVENTION OF GRAFT‐VERSUS‐HOST DISEASE

H. Deeg, H. Ochs, R. Storb, 1984, Transplantation.

Recovery of antibody production in human allogeneic marrow graft recipients: influence of time posttransplantation, the presence or absence of chronic graft-versus-host disease, and antithymocyte globulin treatment.

H. Ochs, K. Sullivan, R. Storb, 1981, Blood.

A Novel Gain-of-Function IKBA Mutation Underlies Ectodermal Dysplasia with Immunodeficiency and Polyendocrinopathy

T. Hökfelt, J. Casanova, C. Picard, 2013, Journal of Clinical Immunology.

Fatal hemophagocytic lymphohistiocytosis associated with Epstein-Barr virus infection in a patient with a novel mutation in the signaling lymphocytic activation molecule-associated protein.

H. Ochs, J. Crowe, J. Whitlock, 2003, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

SARS-CoV-2 infection induces the production of autoantibodies in severe COVID-19 patients in an age-dependent manner

H. Ochs, G. Riemekasten, S. Z. Pour, 2022, medRxiv.

Defective neutrophil chemotaxis with variant ichthyosis, hyperimmunoglobulinemia E, and recurrent infections.

H. Ochs, S. Pincus, R. Clark, 1975, The Journal of pediatrics.

Complement, membrane glycoproteins, and complement receptors: their role in regulation of the immune response.

H. Ochs, P. Beatty, R. Wedgwood, 1986, Clinical immunology and immunopathology.

The NBT slide test: a simple screening method for detecting chronic granulomatous disease and female carriers.

H. Ochs, R. Igo, 1973, The Journal of pediatrics.

Missense mutations of the WASP gene cause intermittent X-linked thrombocytopenia.

L. Notarangelo, H. Ochs, S. Giliani, 2002, Blood.

The role of neutrophil membrane glycoprotein GP-150 in neutrophil adherence to endothelium in vitro.

H. Ochs, P. Beatty, T. Price, 1985, Blood.

Transient blockade of the inducible costimulator pathway generates long-term tolerance to factor VIII after nonviral gene transfer into hemophilia A mice.

G. Freeman, H. Ochs, D. Rawlings, 2008, Blood.

Naked DNA transfer of Factor VIII induced transgene-specific, species-independent immune response in hemophilia A mice.

H. Ochs, R. Kaufman, D. Rawlings, 2004, Molecular therapy : the journal of the American Society of Gene Therapy.

hemophilia A mice long-term tolerance for factor VIII following nonviral gene transfer into Transient blockade of the inducible costimulator pathway generates

G. Freeman, H. Ochs, D. Rawlings, 2008 .

Accumulation of peripheral autoreactive B cells in the absence of functional human regulatory T cells.

H. Ochs, T. Torgerson, C. Cancrini, 2013, Blood.

Intensive postgrafting immune suppression combined with nonmyeloablative conditioning for transplantation of HLA-identical hematopoietic cell grafts: results of a pilot study for treatment of primary immunodeficiency disorders

H. Ochs, T. Torgerson, R. Storb, 2007, Bone Marrow Transplantation.

Lymphocyte alterations in zinc-deficient calves with lethal trait A46.

H. Ochs, J. Ellis, D. Leach, 1989, Veterinary immunology and immunopathology.

Structure and function of the gastrointestinal tract in primary immunodeficiency syndromes (IDS) and in granulocyte dysfunction.

H. Ochs, M. Ament, S. Davis, 1975, Birth defects original article series.

Activated neutrophils disrupt endothelial monolayer integrity by an oxygen radical-independent mechanism.

H. Ochs, S. Schwartz, M. Reidy, 1985, Laboratory investigation; a journal of technical methods and pathology.

Primary immunodeficiencies: 2009 update.

A. Fischer, J. Casanova, L. Notarangelo, 2009, The Journal of allergy and clinical immunology.

Defective humoral immunity in pediatric acquired immune deficiency syndrome.

H. Ochs, R. Wedgwood, A. Rubinstein, 1985, The Journal of pediatrics.

Expanding the Clinical and Genetic Spectrum of Human CD40L Deficiency: The Occurrence of Paracoccidioidomycosis and Other Unusual Infections in Brazilian Patients

J. B. Oliveira, H. Ochs, T. Torgerson, 2011, Journal of Clinical Immunology.

Human Inborn Errors of Immunity: 2019 Update of the IUIS Phenotypical Classification

J. Casanova, J. Franco, A. Bousfiha, 2020, Journal of Clinical Immunology.

Mapping of a syndrome of X-linked thrombocytopenia with thalassemia to band Xp11-12: further evidence of genetic heterogeneity of X-linked thrombocytopenia

K. Niakan, G. Stamatoyannopoulos, H. Ochs, 2000 .

Mapping of a syndrome of X-linked thrombocytopenia with Thalassemia to band Xp11-12: further evidence of genetic heterogeneity of X-linked thrombocytopenia.

K. Niakan, G. Stamatoyannopoulos, H. Ochs, 2000, Blood.

Combined immunodeficiency and reticuloendotheliosis with eosinophilia.

H. Ochs, R. Wedgwood, S. Davis, 1974, The Journal of pediatrics.

Progressive neurodegeneration in patients with primary immunodeficiency disease on IVIG treatment.

R. Kobayashi, L. Notarangelo, C. Cunningham-Rundles, 2002, Clinical immunology.

Autoimmunity in the relatives of patients with immunodeficiency diseases.

H. Ochs, R. Wedgwood, P. Fialkow, 1977, Clinical and experimental immunology.

Chronic Granulomatous Disease: Report on a National Registry of 368 Patients

Richard B. Johnston, John I. Gallin, Harry L. Malech, 2000, Medicine.

V(D)J recombination defects in lymphocytes due to RAG mutations: severe immunodeficiency with a spectrum of clinical presentations.

E. Brooks, K. Schwarz, A. Villa, 2001, Blood.

The molecular basis and treatment of primary immunodeficiency disorders.

H. Ochs, B. Smart, 1997, Current opinion in pediatrics.

Rubella persistence in epidermal keratinocytes and granuloma M2 macrophages in patients with primary immunodeficiencies.

H. Ochs, K. Sullivan, F. Bonilla, 2016, The Journal of allergy and clinical immunology.

Primary Immunodeficiency Diseases: an Update on the Classification from the International Union of Immunological Societies Expert Committee for Primary Immunodeficiency 2015

J. Casanova, J. Franco, A. Bousfiha, 2015, Journal of Clinical Immunology.

Primary immunodeficiency diseases: an update from the International Union of Immunological Societies Primary Immunodeficiency Diseases Classification Committee.

Shigeaki Nonoyama, Mary Ellen Conley, Luigi D Notarangelo, 2007, The Journal of allergy and clinical immunology.

Human Inborn Errors of Immunity: 2019 Update on the Classification from the International Union of Immunological Societies Expert Committee

J. Casanova, J. Franco, A. Bousfiha, 2020, Journal of Clinical Immunology.

In vivo chromosomal instability in ataxia-telangiectasia homozygotes and heterozygotes

H. Ochs, M. Rosin, 1986, Human Genetics.

Canine X-linked severe combined immunodeficiency.

H. Ochs, B. Hartnett, P. Moore, 1999, Veterinary immunology and immunopathology.

Bone marrow transplantation for canine X-linked severe combined immunodeficiency.

H. Ochs, K. Weinberg, B. Hartnett, 1999, Veterinary immunology and immunopathology.

Full immunologic reconstitution following nonconditioned bone marrow transplantation for canine X-linked severe combined immunodeficiency.

H. Ochs, K. Weinberg, B. Hartnett, 1997, Blood.

Improving cellular therapy for primary immune deficiency diseases: recognition, diagnosis, and management.

L. Notarangelo, H. Ochs, J. Puck, 2009, The Journal of allergy and clinical immunology.

Antithymocyte Globulin Treatment of Established Human Graft-Versus-Host Disease by

P. Neiman, H. Ochs, R. Storb, 2011 .

Immunological Reactivity of Human Recipients of Syngeneic and Allogeneic Marrow Grafts

H. Ochs, R. Storb, A. Fefer, 1974 .

Correction to: Human Inborn Errors of Immunity: 2019 Update on the Classification from the International Union of Immunological Societies Expert Committee

J. Casanova, J. Franco, A. Bousfiha, 2020, Journal of Clinical Immunology.

The Hyper IgM Syndrome—An Evolving Story

H. Ochs, Amos Etzioni, 2004, Pediatric Research.

The X-Linked Hyper-IgM Syndrome: Clinical and Immunologic Features of 79 Patients

R. Geha, H. Ochs, E. Stiehm, 2003, Medicine.

H. Ochs, E. Stiehm, D. Rawlings, 2001, The Journal of pediatrics.

Immunologic reactivity in marrow graft recipients.

H. Ochs, R. Storb, E. Thomas, 1976, Transplantation proceedings.

Mycoplasma pneumoniae infections in patients with immunodeficiency syndromes: report of four cases.

H. Ochs, G. Kenny, H. Foy, 1973, The Journal of infectious diseases.

Multiplexed Proteomic Analysis for Diagnosis and Screening of Five Primary Immunodeficiency Disorders From Dried Blood Spots

Jeffrey R. Whiteaker, A. Paulovich, H. Ochs, 2020, Frontiers in Immunology.

X-linked thrombocytopenia (XLT) due to WAS mutations: clinical characteristics, long-term outcome, and treatment options.

A. Fischer, T. Morio, H. Ochs, 2010, Blood.

Absence of memory B cells in patients with common variable immunodeficiency.

H. Ochs, T. Miyawaki, S. Koyasu, 2002, Clinical immunology.

CD40 Ligand Deficiency in Latin America: Clinical, Immunological, and Genetic Characteristics

H. Ochs, L. Bezrodnik, Ileana Moreira, 2022, Journal of Clinical Immunology.

CD40 ligand and MHC class II expression are essential for human peripheral B cell tolerance

C. Cunningham-Rundles, H. Ochs, E. Meffre, 2007, The Journal of experimental medicine.

Molecular analysis of a large cohort of patients with the hyper immunoglobulin M (IgM) syndrome.

H. Ochs, T. Torgerson, Wen-I Lee, 2005, Blood.

The X-Linked Hyper-IgM Syndrome: Clinical and Immunologic Features of 79 Patients

R. Geha, H. Ochs, E. Stiehm, 2003, Medicine.

The CD40 ligand, gp39, is defective in activated T cells from patients with X-linked hyper-IgM syndrome

J. Bajorath, U. Francke, H. Ochs, 1993, Cell.

Hematopoietic stem cell transplantation in patients with gain‐of‐function signal transducer and activator of transcription 1 mutations

T. Morio, H. Ochs, T. Torgerson, 2017, The Journal of allergy and clinical immunology.

DOCK8 Deficiency: Clinical and Immunological Phenotype and Treatment Options - a Review of 136 Patients

J. Orange, A. Schulz, R. Geha, 2015, Journal of Clinical Immunology.

Primary Immunodeficiency Diseases: An Update on the Classification from the International Union of Immunological Societies Expert Committee for Primary Immunodeficiency

A. Fischer, J. Casanova, L. Notarangelo, 2011, Front. Immun..

Primary Immunodeficiency Diseases: an Update on the Classification from the International Union of Immunological Societies Expert Committee for Primary Immunodeficiency 2015

Steven M. Holland, Christoph Klein, Shigeaki Nonoyama, 2009, Front. Immun..

Novel signal transducer and activator of transcription 3 (STAT3) mutations, reduced T(H)17 cell numbers, and variably defective STAT3 phosphorylation in hyper-IgE syndrome.

M. Leppert, H. Ochs, T. Torgerson, 2008, Journal of Allergy and Clinical Immunology.

Clinical course of patients with WASP gene mutations.

Kohsuke Imai, Shigeaki Nonoyama, Yinzhu Jin, 2004, Blood.

First Report of the Hyper-IgM Syndrome Registry of the Latin American Society for Immunodeficiencies: Novel Mutations, Unique Infections, and Outcomes

H. Ochs, T. Torgerson, A. Durandy, 2014, Journal of Clinical Immunology.

Tuberculosis and impaired IL-23–dependent IFN-γ immunity in humans homozygous for a common TYK2 missense variant

J. Casanova, H. Ochs, S. Tangye, 2018, Science Immunology.

Lymphangiomatosis with chylothorax.

I. Bernstein, H. Ochs, F. Berberich, 1975, The Journal of pediatrics.

TH17 cells and regulatory T cells in primary immunodeficiency diseases.

H. Ochs, T. Torgerson, M. Oukka, 2009, The Journal of allergy and clinical immunology.

The 2015 IUIS Phenotypic Classification for Primary Immunodeficiencies

J. Casanova, J. Franco, A. Bousfiha, 2015, Journal of Clinical Immunology.

Gastrointestinal tract and immunodeficiency

H. Ochs, M. Ament, 1976 .

Minor Xp21 chromosome deletion in a male associated with expression of Duchenne muscular dystrophy, chronic granulomatous disease, retinitis pigmentosa, and McLeod syndrome.

C. Disteche, U. Francke, H. Ochs, 1985, American journal of human genetics.

Cancer in primary immunodeficiency diseases: Cancer incidence in the United States Immune Deficiency Network Registry

C. Cunningham-Rundles, H. Ochs, K. Sullivan, 2017, The Journal of allergy and clinical immunology.

The role of complement in the induction of antibody responses.

H. Ochs, M. Frank, R. Wedgwood, 1983, Clinical and experimental immunology.

Functional analysis of human memory B-cell subpopulations: IgD+CD27+ B cells are crucial in secondary immune response by producing high affinity IgM.

H. Ochs, K. Agematsu, K. Sugane, 2003, Clinical immunology.

Defective antibody response to bacteriophage ØX 174 in Down syndrome

H. Ochs, R. Wedgwood, H. Thuline, 1975 .

Congenital stem cell dysfunction associated with Turner-like phenotype.

H. Ochs, T. Price, K. Feldman, 1976, The Journal of pediatrics.

Lazy Leukocyte Syndrome—an Enigma Finally Solved?

A. Etzioni, H. Ochs, 2019, Journal of Clinical Immunology.

International Union of Immunological Societies: 2017 Primary Immunodeficiency Diseases Committee Report on Inborn Errors of Immunity

Steven M. Holland, Christoph Klein, Amos Etzioni, 2017, Journal of Clinical Immunology.

Human Inborn Errors of Immunity: 2019 Update of the IUIS Phenotypical Classification

J. Casanova, J. Franco, A. Bousfiha, 2020, Journal of Clinical Immunology.

Human Inborn Errors of Immunity: 2019 Update on the Classification from the International Union of Immunological Societies Expert Committee

J. Casanova, J. Franco, A. Bousfiha, 2020, Journal of Clinical Immunology.

Transcellular diapedesis is initiated by invasive podosomes.

R. Geha, H. Ochs, H. Dvorak, 2007, Immunity.

A point mutation in gp91-phox of cytochrome b558 of the human NADPH oxidase leading to defective translocation of the cytosolic proteins p47-phox and p67-phox.

H. Ochs, M. de Boer, D. Roos, 1994, The Journal of clinical investigation.

Which Is the Factual Basis, in Theory and Clinical Practice, for the Use of Intravenous Gammaglobulin in the Treatment of Severe Bacterial Infections?

H. Ochs, J. Alexander, H. Deicher, 1979, Vox sanguinis.

Thymosin fraction 5 does not accelerate reconstitution of immunologic reactivity after human marrow grafting

H. Ochs, R. Storb, A. Goldstein, 1983, British journal of haematology.

Normal Immunologic Response to a Neoantigen , Bacteriophage F X-174 , in Baboons With Long-Term Lymphohematopoietic Reconstitution From Highly Purified CD 34

I. Bernstein, H. Ochs, E. Bryant, 1997 .

Maternal-fetal transmission of SIV in macaques: disseminated adenovirus infection in an offspring with congenital SIV infection.

H. Ochs, M. Thouless, C. Tsai, 1991, Journal of medical primatology.

CD40 ligand deficiency causes functional defects of peripheral neutrophils that are improved by exogenous IFN‐&ggr;

L. Notarangelo, H. Ochs, T. Torgerson, 2018, The Journal of allergy and clinical immunology.

Severe food allergy as a variant of IPEX syndrome caused by a deletion in a noncoding region of the FOXP3 gene.

F. Rieux-Laucat, A. Fischer, H. Ochs, 2007, Gastroenterology.

Intravenous immunoglobulin therapy for active, extensive, and medically refractory idiopathic ulcerative or Crohn's colitis.

H. Ochs, D. Levine, R. Haggitt, 1992, The American journal of gastroenterology.

Class switch recombination defects: impact on b cell maturation and antibody responses.

J. Orange, H. Ochs, T. Torgerson, 2020, Clinical immunology.

Hyper IgM Syndrome: a Report from the USIDNET Registry

R. Geha, C. Cunningham-Rundles, H. Ochs, 2016, Journal of Clinical Immunology.

Human uracil–DNA glycosylase deficiency associated with profoundly impaired immunoglobulin class-switch recombination

A. Fischer, H. Ochs, P. Revy, 2003, Nature Immunology.

Activation-Induced Cytidine Deaminase Expression in Human B Cell Precursors Is Essential for Central B Cell Tolerance.

L. Notarangelo, J. Walter, W. Al-Herz, 2015, Immunity.

GPCR-specific autoantibody signatures are associated with physiological and pathological immune homeostasis

B. Engelhardt, H. Ochs, C. Scheibenbogen, 2018, Nature Communications.

CD4+ T-cell-directed antibody responses are maintained in patients with psoriasis receiving alefacept: results of a randomized study.

A. Gottlieb, T. Casale, H. Ochs, 2003, Journal of the American Academy of Dermatology.

Impaired induction of DNA lesions during immunoglobulin class-switch recombination in humans influences end-joining repair

H. Ochs, A. Durandy, K. Imai, 2010, Proceedings of the National Academy of Sciences.

Heterogeneity of chromosomal breakage levels in epithelial tissue of ataxia-telangiectasia homozygotes and heterozygotes

H. Ochs, R. Gatti, E. Boder, 1989, Human Genetics.

Syndrome (HIGM) Molecular Analysis of a Large Cohort of Patients with the Hyper IgM

H. Ochs, T. Torgerson, Wen-I Lee, 2013 .

Isolation of a novel gene mutated in Wiskott-Aldrich syndrome

U. Francke, J. Derry, H. Ochs, 1994, Cell.

WASP is involved in proliferation and differentiation of human haemopoietic progenitors in vitro

T. Morio, H. Ochs, T. Nakahata, 1999, British journal of haematology.

Isolation of a novel gene mutated in Wiskott-Aldrich syndrome.

U. Francke, J. Derry, H. Ochs, 1994, Cell.

Mutations of the Wiskott-Aldrich Syndrome Protein (WASP): hotspots, effect on transcription, and translation and phenotype/genotype correlation.

Silvia Giliani, Yinzhu Jin, Luigi D Notarangelo, 2004, Blood.

Mutations of the human BTK gene coding for bruton tyrosine kinase in X‐linked agammaglobulinemia

M Vihinen, S P Kwan, M. Vihinen, 1999, Human mutation.

Hyper-IgE syndrome is not associated with defects in several candidate toll-like receptor pathway genes.

Stephanie D Rodrigues, A. Aderem, H. Ochs, 2005, Human immunology.

WASP (Wiskott-Aldrich syndrome protein) gene mutations and phenotype

H. Ochs, K. Imai, S. Nonoyama, 2003, Current opinion in allergy and clinical immunology.

Severe COVID-19 Shares a Common Neutrophil Activation Signature with Other Acute Inflammatory States

I. Jurisica, N. Câmara, H. Ochs, 2022, bioRxiv.

The network interplay of interferon and Toll-like receptor signaling pathways in the anti-Candida immune response

I. Jurisica, N. Câmara, H. Ochs, 2021, Scientific Reports.

Involvement of wiskott-aldrich syndrome protein in B-cell cytoplasmic tyrosine kinase pathway.

H. Ochs, T. Kunikata, T. Yamadori, 1999, Blood.

Survival of wild polio by a patient with XLA.

H. Ochs, J. Winkelstein, T. Futatani, 2002, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

The relationship between cytokine and neutrophil gene network distinguishes SARS-CoV-2–infected patients by sex and age

I. Jurisica, N. Câmara, H. Ochs, 2021, JCI insight.

Autoantibodies targeting GPCRs and RAS-related molecules associate with COVID-19 severity

J. Silverberg, I. Jurisica, H. Ochs, 2022, Nature Communications.

IgG subclass deficiencies.

H. Ochs, R. Wedgwood, 1987, Annual review of medicine.

Home-Based Subcutaneous Immunoglobulin Versus Hospital-Based Intravenous Immunoglobulin in Treatment of Primary Antibody Deficiencies: Systematic Review and Meta Analysis

H. Ochs, N. Rezaei, A. Aghamohammadi, 2012, Journal of Clinical Immunology.

Subcutaneous immunoglobulin replacement therapy in the treatment of patients with primary immunodeficiency disease.

H. Ochs, T. Torgerson, S. Skoda-Smith, 2009 .

Prognostic factors for health-related quality of life in adults and children with primary antibody deficiencies receiving SCIG home therapy.

H. Ochs, A N N Gardulf, M. Borte, 2008, Clinical immunology.

Safety and Efficacy of Self-Administered Subcutaneous Immunoglobulin in Patients with Primary Immunodeficiency Diseases

H. Ochs, Sudhir Gupta, U. Nicolay, 2006, Journal of Clinical Immunology.

Octagam® 5%, an Intravenous IgG Product, Is Efficacious and Well Tolerated in Subjects with Primary Immunodeficiency Diseases

H. Ochs, P. Pinciaro, T. J. S. group, 2004, Journal of Clinical Immunology.

Targeted gene editing restores regulated CD40L function in X-linked hyper-IgM syndrome.

H. Ochs, T. Torgerson, A. Scharenberg, 2016, Blood.

Somatic mosaicism in Wiskott–Aldrich syndrome suggests in vivo reversion by a DNA slippage mechanism

D. Nelson, H. Ochs, F. Candotti, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Antibody responses to bacteriophage phi X-174 in human subjects exposed to the antarctic winter-over model of spaceflight.

D. Lugg, H. Ochs, J. Reuben, 2001, The Journal of allergy and clinical immunology.

Astrovirus Encephalitis in Boy with X-linked Agammaglobulinemia

James E. Goldman, W. Ian Lipkin, Mady Hornig, 2010, Emerging infectious diseases.

Structure and function of the Wiskott-Aldrich syndrome protein

Luigi D Notarangelo, L. Notarangelo, H. Ochs, 2005, Current opinion in hematology.

Tyrosine kinase signaling regulates Wiskott-Aldrich syndrome protein function, which is essential for megakaryocyte differentiation.

H. Ochs, T. Takenawa, A. Aruffo, 1997, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.

Giardiasis with malabsorption in X-linked agammaglobulinemia.

H. Ochs, M. Ament, S. Davis, 1972, The New England journal of medicine.

Immune dysregulation, polyendocrinopathy, enteropathy, and X-linked inheritance (IPEX), a syndrome of systemic autoimmunity caused by mutations of FOXP3, a critical regulator of T-cell homeostasis

H. Ochs, T. Torgerson, E. Gambineri, 2003, Current opinion in rheumatology.

Integrative systems immunology uncovers molecular networks of the cell cycle that stratify COVID‐19 severity

N. Câmara, H. Ochs, H. Nakaya, 2023, Journal of medical virology.

Severe COVID-19 Shares a Common Neutrophil Activation Signature with Other Acute Inflammatory States

I. Jurisica, N. Câmara, H. Ochs, 2021, bioRxiv.

A novel mutant γc chain from a patient with typical phenotype of X‐linked severe combined immunodeficiency (SCID) has partial signalling function for mediating IL‐2 and IL‐4 receptor action

H. Ochs, K. Kuropatwinski, H. Baumann, 1999, Clinical and experimental immunology.

Home-based immunoglobulin infusion therapy: quality of life and patient health perceptions.

R. Kobayashi, H. Ochs, J. Evans, 1991, Annals of allergy.

Subcutaneous immunoglobulin replacement therapy in the treatment of patients with primary immunodeficiency disease

H. Ochs, T. Torgerson, S. Skoda-Smith, 2010, Therapeutics and clinical risk management.

STAT3 mutation in the original patient with Job's syndrome.

H. Ochs, T. Torgerson, E. Renner, 2007, The New England journal of medicine.

Missense mutations affecting a conserved cysteine pair in the TH domain of Btk

M. Vihinen, H. Ochs, S. Koutaniemi, 1997, FEBS letters.

Single-cell analysis of normal and FOXP3-mutant human T cells: FOXP3 expression without regulatory T cell development.

A. Rudensky, H. Ochs, T. Torgerson, 2006, Proceedings of the National Academy of Sciences of the United States of America.

Human tyrosine kinase 2 deficiency reveals its requisite roles in multiple cytokine signals involved in innate and acquired immunity.

T. Morio, H. Ochs, H. Takada, 2006, Immunity.

The Wiskott-Aldrich syndrome

H. Ochs, 1998, Springer Seminars in Immunopathology.

The pleckstrin homology domain of the Wiskott-Aldrich syndrome protein is involved in the organization of actin cytoskeleton.

T. Morio, H. Ochs, T. Takenawa, 1999, Clinical immunology.

The Wiskott-Aldrich syndrome

H. Ochs, 2001, The Israel Medical Association journal : IMAJ.

Collagen induces tyrosine phosphorylation of Wiskott-Aldrich syndrome protein in human platelets.

H. Ochs, B. Druker, Y. Miyakawa, 1998, Blood.

International Union of Immunological Societies: 2017 Primary Immunodeficiency Diseases Committee Report on Inborn Errors of Immunity

J. Casanova, J. Franco, A. Bousfiha, 2017, Journal of Clinical Immunology.

History of primary immunodeficiency diseases

H. Ochs, W. Hitzig, 2012, Current opinion in allergy and clinical immunology.

Phosphorylation of the oxidase-related 48K phosphoprotein family in the unusual autosomal cytochrome-negative and X-linked cytochrome-positive types of chronic granulomatous disease.

S. Malawista, H. Ochs, B. Babior, 1988, Blood.

Familial hemophagocytic lymphohistiocytosis in two brothers with X‐linked agammaglobulinemia

H. Ochs, T. Torgerson, J. Neglia, 2008, Pediatric blood & cancer.

Human Inborn Errors of Immunity: 2022 Update on the Classification from the International Union of Immunological Societies Expert Committee

J. Casanova, J. Franco, A. Bousfiha, 2022, Journal of Clinical Immunology.

Autoimmunity and Inflammation in X-linked Agammaglobulinemia

C. Cunningham-Rundles, H. Ochs, K. Sullivan, 2014, Journal of Clinical Immunology.

A new RFLP marker, SP282, at the btk locus for genetic analysis in X‐linked agammaglobulinaemia families

H. Ochs, A. Walker, Sudhir Gupta, 1994, Prenatal diagnosis.

Finally Found: The Ataxia-Telangiectasia Gene and its Function

H. Ochs, R. Gatti, D. McCurdy, 2014 .

Characterization of soluble CD40 ligand released from human activated platelets.

T. Morio, H. Ochs, S. Mizutani, 2001, Journal of medical and dental sciences.

CD40 Ligand Mutants Responsible for X-linked Hyper-IgM Syndrome Associate with Wild Type CD40 Ligand*

H. Ochs, W. Osborne, K. Seyama, 1999, The Journal of Biological Chemistry.

Immunologic reconstitution following bone marrow transplantation for X-linked hyper IgM syndrome.

H. Ochs, R. Nelson, N. Day, 2001, Clinical immunology.

Heterogeneity of phenotype in two siblings with adenosine deaminase deficiency.

H. Ochs, D. Umetsu, M. Hershfield, 1994, The Journal of allergy and clinical immunology.

X-linked thrombocytopenia identified by flow cytometric demonstration of defective Wiskott-Aldrich syndrome protein in lymphocytes.

H. Kanegane, H. Ochs, T. Miyawaki, 2000, Blood.

Immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome: a model of immune dysregulation

H. Ochs, T. Torgerson, 2002, Current opinion in allergy and clinical immunology.

Localization of the gene for the Wiskott-Aldrich syndrome between two flanking markers, TIMP and DXS255, on Xp11.22-Xp11.3.

J. Ott, T. Lehner, H. Ochs, 1991, Genomics.

Wiskott–Aldrich Syndrome: from a Fatal Hematologic Disorder to a Curable Immunodeficiency

H. Ochs, B. Belohradsky, 2014 .

Dock8 Functions as an Adaptor That Links Toll-like Receptor– Myd88 Signaling to B Cell Activation Hhs Public Access

Alessandro Plebani, Rima Wakim, Kate Fitzgerald, 2022 .

Primary Immunodeficiency Diseases Associated with Neurologic Manifestations

H. Ochs, N. Rezaei, A. Aghamohammadi, 2012, Journal of Clinical Immunology.

A rare polyadenylation signal mutation of the FOXP3 gene (AAUAAA→AAUGAA) leads to the IPEX syndrome

Hans D. Ochs, Mary E. Brunkow, H. Ochs, 2001, Immunogenetics.

Immune response of a patient with deficiency of the fourth component of complement and systemic lupus erythematosus.

H. Ochs, R. Wedgwood, C. Jackson, 1979, The New England journal of medicine.

Genetics of primary immune deficiencies

H. Ochs, T. Torgerson, 2020, Stiehm's Immune Deficiencies.

Diagnostic approach to the hyper-IgE syndromes: immunologic and clinical key findings to differentiate hyper-IgE syndromes from atopic dermatitis.

H. Ochs, T. Torgerson, V. Wahn, 2010, The Journal of allergy and clinical immunology.

Immune dysregulation, polyendocrinopathy, enteropathy, X-linked: forkhead box protein 3 mutations and lack of regulatory T cells.

H. Ochs, T. Torgerson, 2007, The Journal of allergy and clinical immunology.

DOCK8 Deficiency: Clinical and Immunological Phenotype and Treatment Options - a Review of 136 Patients

J. Orange, A. Schulz, R. Geha, 2015, Journal of Clinical Immunology.

First Report of the Hyper-IgM Syndrome Registry of the Latin American Society for Immunodeficiencies: Novel Mutations, Unique Infections, and Outcomes

H. Ochs, T. Torgerson, A. Durandy, 2014, Journal of Clinical Immunology.

Cross-sectional analysis of students and school workers reveals a high number of asymptomatic SARS-CoV-2 infections during school reopening in Brazilian cities

H. Ochs, L. Cuevas, R. Ramos, 2022, Heliyon.

X-Linked Agammaglobulinemia: Infection Frequency and Infection-Related Mortality in the USIDNET Registry

C. Cunningham-Rundles, H. Ochs, K. Sullivan, 2022, Journal of Clinical Immunology.

Immune deficiencies , infection , and systemic immune disorders Stable hematopoietic cell engraftment after low-intensity nonmyeloablative conditioning in patients with immune dysregulation , polyendocrinopathy , enteropathy , X-linked syndrome

H. Ochs, T. Torgerson, R. Storb, 2010 .

adenosine deaminase deficiency Antibody responses to bacteriophage phi X174 in patients with

H. Ochs, R. Sorensen, R. Buckley, 2011 .

Nonmyeloablative Conditioning Followed by Allogeneic Marrow Grafts for Treatment of Primary Immune Deficiency Disorders: Preliminary Results of a Phase II Study

H. Ochs, T. Torgerson, R. Storb, 2011 .

ADA deficiency, immunologic and biochemical abnormalities, treatment

H. Ochs, 1990 .

Identification of a closely linked DNA marker, DXS178, to further refine the X-linked agammaglobulinemia locus.

S P Kwan, J. Terwilliger, J. Ott, 1990, Genomics.

B-cell function in canine X-linked severe combined immunodeficiency.

H. Ochs, K. Weinberg, B. Hartnett, 1998, Veterinary immunology and immunopathology.

Absence of IgD-CD 27 ( + ) memory B cell population in X-linked hyper-IgM syndrome

H. Ochs, A. Komiyama, S. Nonoyama, 2018 .

Clinical, Immunological, and Molecular Heterogeneity of 173 Patients With the Phenotype of Immune Dysregulation, Polyendocrinopathy, Enteropathy, X-Linked (IPEX) Syndrome

H. Ochs, T. Torgerson, E. Gambineri, 2018, Front. Immunol..

In vivo behavior of neutrophils from two patients with distinct inherited leukocyte adhesion deficiency syndromes.

H. Ochs, U. V. von Andrian, J. Paulson, 1993, The Journal of clinical investigation.

Homozygous Splice ADA2 Gene Mutation Causing ADA-2 Deficiency

H. Ochs, T. Torgerson, M. Hershfield, 2019, Journal of Clinical Immunology.

Actin cytoskeletal function is spared, but apoptosis is increased, in WAS patient hematopoietic cells.

H. Ochs, R. Rengan, G. Omann, 2000, Blood.

Abnormalities of lymphocyte locomotion in immunodeficiency disease.

H. Ochs, D. V. Van Epps, A. el-Naggar, 1983, Clinical and experimental immunology.

Novel Artemis gene mutations of radiosensitive severe combined immunodeficiency in Japanese families

Y. Fukushima, H. Ochs, A. Komiyama, 2003, Human Genetics.

Gastrointestinal Manifestations in X-linked Agammaglobulinemia

J. Walter, H. Ochs, M. Dorsey, 2017, Journal of Clinical Immunology.

The 2015 IUIS Phenotypic Classification for Primary Immunodeficiencies

J. Casanova, J. Franco, A. Bousfiha, 2015, Journal of Clinical Immunology.

A Phenotypic Approach for IUIS PID Classification and Diagnosis: Guidelines for Clinicians at the Bedside

J. Casanova, L. Notarangelo, R. Geha, 2013, Journal of Clinical Immunology.

characteristics, long-term outcome, and treatment options mutations: clinical WAS X-linked thrombocytopenia (XLT) due to

A. Fischer, T. Morio, H. Ochs, 2011 .

Induction of T-lymphocyte differentiation by thymic epithelial cell monolayers.

H. Ochs, R. Wedgwood, J. Willis-Carr, 1978, Clinical immunology and immunopathology.

Decreased somatic hypermutation induces an impaired peripheral B cell tolerance checkpoint.

M. van der Burg, L. Notarangelo, J. Walter, 2016, The Journal of clinical investigation.

Primary immunodeficiency disorders: general classification, new molecular insights, and practical approach to diagnosis and treatment.

H. Ochs, D. Hagin, 2014, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

Perinatal infection with human immunodeficiency virus. Specific antibody responses by the neonate.

H. Ochs, M. Dufford, K. Pyun, 1987, The New England journal of medicine.

Predominance of B-lymphocyte function after cultured thymus fragment therapy in severe combined immunodeficiency disease.

James F. Jones, H. Ochs, R. Hong, 1980, Clinical immunology and immunopathology.

Immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome and the scurfy mutant mouse

H. Ochs, R. Khattri, M. Brunkow, 2002 .

Successful hematopoietic cell transplantation in a patient with X‐linked agammaglobulinemia and acute myeloid leukemia

H. Ochs, T. Torgerson, J. López-Guisa, 2015, Pediatric blood & cancer.

Defective self-reactive antibody repertoire of serum IgM in patients with hyper-IgM syndrome.

A. Fischer, L. Notarangelo, H. Ochs, 1999, Journal of immunology.

R‐loops cause genomic instability in T helper lymphocytes from patients with Wiskott‐Aldrich syndrome

H. Ochs, L. Dupré, Seong‐Su Han, 2017, The Journal of allergy and clinical immunology.

Regulatory T cells in primary immunodeficiency diseases

H. Ochs, T. Torgerson, 2007, Current opinion in allergy and clinical immunology.

Psychosocial stress moderates the relationship of cancer history with natural killer cell activity

H. Ochs, K. Syrjala, I. Siegler, 1998, Annals of behavioral medicine : a publication of the Society of Behavioral Medicine.

FOXP3 Inhibits Activation-Induced NFAT2 Expression in T Cells Thereby Limiting Effector Cytokine Expression1

H. Ochs, T. Torgerson, I. Dozmorov, 2009, The Journal of Immunology.

Low serum thymic hormone levels in patients with chronic graft-versus-host disease.

H. Ochs, R. Storb, R. Good, 1982, Blood.

Cogan syndrome in childhood.

H. Ochs, S. Kundell, 1980, The Journal of pediatrics.

Humoral immunity in steroid-dependent children with asthma and hypogammaglobulinemia.

H. Ochs, E. Gelfand, G. Lack, 1996, The Journal of pediatrics.

Induction, binding specificity and function of human ICOS

H. Ochs, B. Ludewig, H. Mages, 2000, European journal of immunology.

patient hematopoietic cells Actin cytoskeletal function is spared, but apoptosis is increased, in WAS

H. Ochs, R. Rengan, G. Omann, 2013 .

The role of CD40L (gp39)/CD40 in T/B cell interaction and primary immunodeficiency.

H. Ochs, A. Aruffo, D. Hollenbaugh, 1994, Research in immunology.

CD40L modulates transcriptional signatures of neutrophils in the bone marrow associated with development and trafficking

I. Jurisica, H. Ochs, Yassir A. Mohamed, 2021, JCI insight.

Ambrisentan, an endothelin receptor type A-selective antagonist, inhibits cancer cell migration, invasion, and metastasis

H. Busch, H. Ochs, G. Riemekasten, 2020, Scientific Reports.

A custom 148 gene‐based resequencing chip and the SNP explorer software: new tools to study antibody deficiency

S. Chanock, M. Yeager, J. Orange, 2010, Human mutation.

Enteroviral meningoencephalitis as a complication of X-linked hyper IgM syndrome.

H. Ochs, H. Rotbart, L. Weiner, 1999, The Journal of pediatrics.

FOXP3 acts as a rheostat of the immune response

S. Ziegler, H. Ochs, T. Torgerson, 2005, Immunological reviews.

In vitro responses to a B-lymphoblastoid cell line in immunodeficiency diseases

H. Ochs, J. Sullivan, R. Wedgwood, 1982, Journal of Clinical Immunology.

IPEX, FOXP3 and regulatory T-cells: a model for autoimmunity

Hans D. Ochs, H. Ochs, T. Torgerson, 2007, Immunologic research.

Analysis of somatic hypermutations in the IgM switch region in human B cells.

H. Ochs, A. Durandy, Kanako Mitsui-Sekinaka, 2014, The Journal of allergy and clinical immunology.

Soluble CD40L is associated with increased oxidative burst and neutrophil extracellular trap release in Behçet’s disease

H. Ochs, T. Torgerson, L. Andrade, 2017, Arthritis Research & Therapy.

Intravenous gamma globulin (IVGG) therapy in immunodeficiency syndromes

H. Ochs, R. Wedgwood, S. Davis, 1974 .

Leukocyte Adhesion Deficiency Type II is a generalized defect of de novo GDP-fucose biosynthesis. Endothelial cell fucosylation is not required for neutrophil rolling on human nonlymphoid endothelium.

A Etzioni, A. Karsan, H. Ochs, 1998, The Journal of clinical investigation.

The effect of graft-versus-host disease on reconstitution of the immune system following marrow transplantation for aplastic anemia or leukemia.

H. Ochs, R. Storb, E. Thomas, 1978, Transplantation proceedings.

Inheritance and genetic linkage of transcobalamin II

H. Ochs, S. Yang, B. DuPont, 2004, Human Genetics.

CD11/CD18-independent neutrophil adherence to inducible endothelial-leucocyte adhesion molecules (E-LAM) in vitro.

H. Ochs, P. Beatty, T. Carlos, 1989, Immunology.

Immunoglobulin variable heavy chain cDNA sequence from a patient with X-linked agammaglobulinemia.

H. Ochs, R. Wedgwood, F. Mortari, 1991, Nucleic acids research.

Lymphocyte Proliferation Is Associated with Gender, Caregiving, and Psychosocial Variables in Older Adults

H. Ochs, P. Vitaliano, J. Scanlan, 2001, Journal of Behavioral Medicine.

Autoantibodies targeting G protein-coupled receptors: An evolving history in autoimmunity. Report of the 4th international symposium.

J. D. de Vries-Bouwstra, H. Ochs, Y. Shoenfeld, 2023, Autoimmunity reviews.

Cross‐sectional analysis reveals autoantibody signatures associated with COVID‐19 severity

H. Ochs, Y. Shoenfeld, C. Scheibenbogen, 2023, Journal of medical virology.

Genetic analysis of contiguous X-chromosome deletion syndrome encompassing the BTK and TIMM8A genes

H. Kanegane, H. Ochs, M. Yamada, 2011, Journal of Human Genetics.

Autoantibodies linked to autoimmune diseases associate with COVID-19 outcomes

J. Silverberg, N. Câmara, H. Ochs, 2022, medRxiv.

The relationship between autoantibodies targeting GPCRs and the renin-angiotensin system associates with COVID-19 severity

H. Ochs, Y. Shoenfeld, G. Riemekasten, 2021, medRxiv.

Histocompatibility antigens in childhood-onset arthritis.

H. Ochs, B. Nisperos, E. Thomas, 1976, The Journal of pediatrics.

Immune reactivity in dogs with spontaneous malignancy.

H. Ochs, R. Storb, E. Thomas, 1974, Journal of the National Cancer Institute.

Use of thymic grafts or thymic factors to augment immunologic recovery after bone marrow transplantation: brief report with 2 to 12 years' follow-up.

H. Ochs, K. Sullivan, R. Storb, 1988, Bone marrow transplantation.

Abnormal antibody responses in patients with persistent generalized lymphadenopathy

H. Handsfield, H. Ochs, A. Collier, 2004, Journal of Clinical Immunology.

Postgrafting Immune Suppression Combined with Nonmyeloablative Conditioning for Transplantation of HLA-Identical Hematopoietic Cell Grafts: Results of a Phase I Study for Treatment of Immunodeficiency Disorders.

H. Ochs, T. Torgerson, R. Storb, 2005 .

Pulmonary angiitis with atypical lymphoreticular infiltrates in Wiskott-Aldrich syndrome: possible relationship of lymphomatoid granulomatosis and EBV infection.

H. Ochs, D. Purtilo, J. Haas, 1986, Clinical immunology and immunopathology.

Necrotizing lymphoid vasculitis in X-linked lymphoproliferative syndrome.

H. Ochs, H. Lipscomb, D. Volsky, 1985, Archives of pathology & laboratory medicine.

Epstein-Barr virus-induced lymphoblastoid cell lines derived from the peripheral blood of patients with X-linked agammaglobulinemia can secrete IgM

H. Ochs, D. Levitt, R. Wedgwood, 1984, Journal of Clinical Immunology.

Clinical Phenotype and Long Term Outcome in a Large Cohort of X-Linked Thrombocytopenia (XLT)/Mild Wiskott-Aldrich-Syndrome Patients

A. Fischer, T. Morio, H. Ochs, 2008 .

Stress, sleep problems, and immune function in persons with cancer histories

H. Ochs, I. Siegler, P. Prinz, 2000 .

Classification of mutations in the human CD40 ligand, gp39, that are associated with X‐linked hyper IgM syndrome

K Seyama, J Bajorath, J. Bajorath, 1996, Protein science : a publication of the Protein Society.

Transient immune deficiency in patients with acute Epstein-Barr virus infection.

H. Ochs, E. Clark, A. Junker, 1986, Clinical immunology and immunopathology.

Patients with abnormal IgM levels: assessment, clinical interpretation, and treatment.

H. Ochs, 2008, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

DOCK8 and STAT3 dependent inhibition of IgE isotype switching by TLR9 ligation in human B cells.

R. Geha, W. Al-Herz, T. Chatila, 2017, Clinical immunology.

Signal transducer and activator of transcription 3 mutation with invasive eosinophilic disease

H. Ochs, H. Tcheurekdjian, R. Hostoffer, 2012, Allergy & rhinology.

Wiskott–Aldrich syndrome protein is involved in αIIbβ3‐mediated cell adhesion

Shigeaki Nonoyama, Hans D. Ochs, S. Tsuboi, 2006 .

Wiskott–Aldrich syndrome protein is involved in a IIb b 3-mediated cell adhesion

S. Tsuboi, H. Ochs, S. Nonoyama, 2006 .

Wiskott-Aldrich syndrome protein is involved in alphaIIb beta3-mediated cell adhesion.

S. Tsuboi, H. Ochs, S. Nonoyama, 2006, EMBO reports.

Recommendations for live viral and bacterial vaccines in immunodeficient patients and their close contacts.

J. Orange, L. Notarangelo, C. Cunningham-Rundles, 2014, The Journal of allergy and clinical immunology.

X-linked Hyper IgM Syndrome Presenting as Pulmonary Alveolar Proteinosis

H. Ochs, T. Torgerson, J. Verbsky, 2016, Journal of Clinical Immunology.

Intravenous immunoglobulin in idiopathic inflammatory bowel disease: results of an open-label therapeutic trial

H. Ochs, D. Levine, R. Haggitt, 1991 .

Mutations of the WASP gene in 10 Japanese patients with Wiskott-Aldrich syndrome and X-linked thrombocytopenia.

T. Morio, H. Ochs, S. Nonoyama, 2000, International journal of hematology.

Hematopoietic Stem Cell Transplantation for X-Linked Thrombocytopenia With Mutations in the WAS gene

L. Notarangelo, T. Morio, H. Ochs, 2014, Journal of Clinical Immunology.

The Wiskott-Aldrich syndrome.

H. Ochs, 1998, Clinical reviews in allergy & immunology.

Flebogamma® 5 % DIF Intravenous Immunoglobulin for Replacement Therapy in Children with Primary Immunodeficiency Diseases

H. Ochs, T. Craig, J. Sleasman, 2016, Journal of Clinical Immunology.

Role of C3 in humoral immunity. Defective antibody production in C3-deficient dogs.

H. Ochs, J. Morris, L. Cork, 1988, Journal of immunology.

Expanding the Clinical and Genetic Spectrum of Human CD40L Deficiency: The Occurrence of Paracoccidioidomycosis and Other Unusual Infections in Brazilian Patients

J. B. Oliveira, H. Ochs, T. Torgerson, 2012, Journal of Clinical Immunology.

FOXP 3 Inhibits Activation-Induced NFAT 2 Expression in T Cells Thereby Limiting Effector Cytokine Expression 1

H. Ochs, T. Torgerson, I. Dozmorov, 2009 .

Dried Blood Spots, an Affordable Tool to Collect, Ship, and Sequence gDNA from Patients with an X-Linked Agammaglobulinemia Phenotype Residing in a Developing Country

R. Kobayashi, H. Ochs, T. Torgerson, 2018, Front. Immunol..

Bruton's Tyrosine Kinase (BTK) Is Present in Normal Platelets, and Its Absence Identifies Patients with X-Linked Agammaglobulinemia (XLA) and Carrier Females

H. Ochs, Y. Baba, A. Oda, 1999, British journal of haematology.

CD4 and CD8 Counts Are Associated With Interactions of Gender and Psychosocial Stress

S. Borson, H. Ochs, P. Vitaliano, 1998, Psychosomatic medicine.

Intravenous immunoglobulin 10% in children with primary immunodeficiency diseases.

R. Kobayashi, H. Ochs, J. Moy, 2018, Immunotherapy.

Efficacy and Safety of Human Intravenous Immunoglobulin 10% (Panzyga®) in Patients with Primary Immunodeficiency Diseases: a Two-Stage, Multicenter, Prospective, Open-Label Study

R. Kobayashi, H. Ochs, Sudhir Gupta, 2017, Journal of Clinical Immunology.

Flebogamma® 5 % DIF Intravenous Immunoglobulin for Replacement Therapy in Children with Primary Immunodeficiency Diseases

H. Ochs, T. Craig, J. Sleasman, 2016, Journal of Clinical Immunology.

Conversion from Intravenous to Subcutaneous Immunolgobulin Therapy: Relationship Between Dose, Serum Trough IgG Concentration and Infection Rate in Patients with Primary Immune Deficiency Diseases

H. Ochs, M. Berger, 2006 .

Pharmacokinetics of a novel human intravenous immunoglobulin 10% in patients with primary immunodeficiency diseases: Analysis of a phase III, multicentre, prospective, open‐label study

R. Kobayashi, H. Ochs, Sudhir Gupta, 2018, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Evaluation of CD4+ T cell function In vivo in HIV-infected patients as measured by bacteriophage phiX174 immunization.

H. Ochs, H. Lane, M. Feinberg, 2000, The Journal of infectious diseases.

Efficacy and safety of home‐based subcutaneous immunoglobulin replacement therapy in paediatric patients with primary immunodeficiencies

H. Ochs, M. Borte, E. Bernatowska, 2011, Clinical and experimental immunology.

Modified immune globulin: Its use in the prophylactic treatment of patients with immune deficiency

H. Ochs, R. Wedgwood, S. Fischer, 1982, Journal of Clinical Immunology.

BTKbase, mutation database for X-linked agammaglobulinemia (XLA)

Mauno Vihinen, Pentti Riikonen, Ilkka Lappalainen, 1998, Nucleic Acids Res..

The clinical spectrum and immunopathological mechanisms underlying ZIKV-induced neurological manifestations.

N. Câmara, H. Ochs, G. Cabral-Miranda, 2021, PLoS neglected tropical diseases.

The urgent need for integrated science to fight COVID-19 pandemic and beyond

Michael R Hamblin, C. Camargo, R. Kelishadi, 2020, Journal of Translational Medicine.

Bispecific monoclonal antibody complexes bound to primate erythrocyte complement receptor 1 facilitate virus clearance in a monkey model.

H. Ochs, R. Taylor, E. Gilbert, 1997, Journal of immunology.

Diagnosis and evaluation of primary panhypogammaglobulinemia: a molecular and genetic challenge.

H. Ochs, T. Torgerson, E. Gelfand, 2013, Journal of Allergy and Clinical Immunology.

Contiguous X-chromosome Deletion Syndrome Encompassing the BTK, TIMM8A, TAF7L, and DRP2 Genes

H. Ochs, K. Sullivan, A. Šedivá, 2007, Journal of Clinical Immunology.

Isolation of cosmid and cDNA clones in the region surrounding the BTK gene at Xq21.3-q22.

D. Bentley, D. Vetrie, L. Notarangelo, 1994, Genomics.

Survival of antigen-specific antibody following administration of intravenous immunoglobulin in patients with primary immunodeficiency diseases.

H. Ochs, H. Hill, L. Corey, 1988, Monographs in allergy.

Quantity does not equal quality: Scientific principles cannot be sacrificed

Michael R Hamblin, H. Ochs, J. Talmadge, 2020, International Immunopharmacology.

Identification of residues on CD40 and its ligand which are critical for the receptor-ligand interaction.

J Bajorath, J. Bajorath, H. Ochs, 1995, Biochemistry.

HLA typing of cultured amniotic cells for the prenatal diagnosis of complement C4 deficiency

H. Ochs, B. Dupont, M. Pollack, 1980 .

HLA typing of cultured amniotic cells for the prenatal diagnosis of complement C4 deficiency.

H. Ochs, B. Dupont, M. Pollack, 1980, Clinical genetics.

Effects of administration of a single dose of a humanized monoclonal antibody to CD11a on the immunobiology and clinical activity of psoriasis.

M. Lebwohl, K. Wittkowski, H. Ochs, 2000, Journal of the American Academy of Dermatology.

Coding-region alterations in BTK do not universally cause X-linked agammaglobulinemia.

H. Ochs, E. Gelfand, J. Abbott, 2013, The Journal of allergy and clinical immunology.

BTKbase, mutation database for X-linked agammaglobulinemia (XLA)

Mauno Vihinen, Christine Kinnon, Igor Vorechovsky, 1996, Nucleic Acids Res..

A Phenotypic Approach for IUIS PID Classification and Diagnosis: Guidelines for Clinicians at the Bedside

A. Fischer, J. Casanova, L. Notarangelo, 2013, Journal of Clinical Immunology.

H. Ochs, B. Grimbacher, A. Filipovich, 2016, Journal of Clinical Immunology.

Ocular Involvement in Primary Immunodeficiency Diseases

H. Ochs, N. Rezaei, A. Aghamohammadi, 2013, Journal of Clinical Immunology.

BTKbase: XLA-mutation registry.

M. Vihinen, H. Ochs, H. Lehväslaiho, 1996, Immunology today.

X-linked lymphoproliferative syndrome: abnormal antibody responses to bacteriophage phi X 174.

H. Ochs, D. Purtilo, J. Sullivan, 1983, Birth defects original article series.

Correction to: Human Inborn Errors of Immunity: 2019 Update on the Classification from the International Union of Immunological Societies Expert Committee

J. Casanova, J. Franco, A. Bousfiha, 2020, Journal of Clinical Immunology.

Absence of functional fetal regulatory T cells in humans causes in utero organ-specific autoimmunity.

Matthew C. Altman, H. Ochs, T. Torgerson, 2017, The Journal of allergy and clinical immunology.

X-linked hyper IgM syndrome: a report of the first case in Thailand with a confirmed mutation of CD40 ligand gene.

H. Ochs, S. Santadusit, P. Vichyanond, 2000, Asian Pacific journal of allergy and immunology.

X-Linked Hyper-IgM Syndrome

H. Ochs, H. Rotbart, L. Weiner, 2020 .

Efficacy and Safety of Human Intravenous Immunoglobulin 10% (Panzyga®) in Patients with Primary Immunodeficiency Diseases: a Two-Stage, Multicenter, Prospective, Open-Label Study

R. Kobayashi, H. Ochs, Sudhir Gupta, 2017, Journal of Clinical Immunology.

IgG subclass levels in the serum of patients with primary immunodeficiency.

H. Ochs, V. Oxelius, R. Wedgwood, 1986, Monographs in allergy.

Immune deficiencies , infection , and systemic immune disorders Reduced thymic output , cell cycle abnormalities , and increased apoptosis of T lymphocytes in patients with cartilage-hair hypoplasia

K. Strauss, D. Morton, L. Notarangelo, 2011 .

Josiah F. Wedgwood (1950-2009).

A. Fischer, L. Notarangelo, R. Geha, 2010, The Journal of allergy and clinical immunology.

Tubular reticular structures in peripheral mononuclear cells of males with chronic granulomatous disease and female carriers

H. Ochs, A. Ammann, D. Wara, 1975 .

Regulation of antibody responses: the role of complement and adhesion molecules.

H. Ochs, S. Nonoyama, R. Wedgwood, 1993, Clinical immunology and immunopathology.

The clinical, molecular, and therapeutic features of patients with IL10/IL10R deficiency: a systematic review.

H. Ochs, Niusha Sharifinejad, M. Zaki-Dizaji, 2022, Clinical and experimental immunology.

Intra-amniotic inoculation of pigtailed macaque (Macaca nemestrina) fetuses with SIV and HIV-1.

H. Ochs, C. Tsai, R. Benveniste, 1993, Journal of medical primatology.

Inducible CO-stimulator molecule, a candidate gene for defective isotype switching, is normal in patients with hyper-IgM syndrome of unknown molecular diagnosis.

H. Ochs, E. Gambineri, A. Welcher, 2003, The Journal of allergy and clinical immunology.

The home administration of IVIG in children with primary immunodeficiency

H. Ochs, N. Lee, S. Fischer, 1991 .

Immune responses in adult female volunteers during the bed-rest model of spaceflight: antibodies and cytokines.

Gerald Sonnenfeld, Bruce Thompson, H. Ochs, 2008, The Journal of allergy and clinical immunology.

Immune deficiencies , infection , and systemic immune disorders Immune responses in adult female volunteers during the bedrest model of spaceflight : Antibodies and cytokines

H. Ochs, J. Reuben, Bang‐Ning Lee, 2009 .

The molecular basis of X-linked agammaglobulinemia, hyper-IgM syndrome, and severe combined immunodeficiency in humans.

H. Ochs, A. Aruffo, D. Hollenbaugh, 1994, Current opinion in hematology.

Genetic Analysis of C 4 Deficiency

H. Ochs, C. Alper, Z. Awdeh, 2022 .

Bruton's tyrosine kinase is a substrate of calpain in human platelets

H. Ochs, D. Dash, Saikat Mukhopadhyay, 2001, FEBS letters.

Costimulation via vascular cell adhesion molecule-1 induces in T cells increased responsiveness to the CD28 counter-receptor B7.

P. Linsley, H. Ochs, A. Aruffo, 1993, Cellular immunology.

Primary immunodeficiency diseases : a molecular and cellular approach

H. Ochs, J. Puck, C. I. Smith, 2014 .

The human immunodeficiency virus-infected infant. A diagnostic dilemma.

H. Ochs, 1989, American journal of diseases of children.

X-linked agammaglobulinemia in northern Thailand.

H. Ochs, M. Trakultivakorn, 2006, Asian Pacific journal of allergy and immunology.

Interleukin-21 stimulates B-cell immunoglobulin E synthesis in human beings concomitantly with activation-induced cytidine deaminase expression and differentiation into plasma cells.

H. Ochs, K. Agematsu, K. Sugane, 2009, Human immunology.

Prioritization of Evidence-Based Indications for Intravenous Immunoglobulin

J. Orange, C. Cunningham-Rundles, H. Ochs, 2013, Journal of Clinical Immunology.

In vivo neutrophil and lymphocyte function studies in a patient with leukocyte adhesion deficiency type II.

A Etzioni, H. Ochs, R. Gershoni-baruch, 1994, Blood.

Interferon-γ receptor deficiency: An expanding clinical phenotype?

J. Casanova, H. Ochs, 1999 .

Interferon-gamma receptor deficiency: An expanding clinical phenotype?

J. Casanova, H. Ochs, 1999, Jornal de Pediatria.

The role of adhesion molecules in the regulation of antibody responses.

H. Ochs, A. Aruffo, S. Nonoyama, 1993, Seminars in hematology.

IL-10 Deficiency Unleashes an Influenza-Specific Th17 Response and Enhances Survival against High-Dose Challenge1

H. Ochs, Jonathan D. Curtis, D. Rawlings, 2009, The Journal of Immunology.

Severe COVID-19 patients exhibit elevated levels of autoantibodies targeting cardiolipin and platelet glycoprotein with age: a systems biology approach

H. Ochs, A. Rosenberg, H. Amital, 2023, npj aging.

Primary Immunodeficiency Diseases: An Update on the Classification from the International Union of Immunological Societies Expert Committee for Primary Immunodeficiency

J. Casanova, L. Notarangelo, R. Geha, 2014, Front. Immunol..

Correction of equine severe combined immunodeficiency by bone marrow transplantation.

H. Ochs, W. Davis, N. Magnuson, 1986, Transplantation.

Bed rest and immunity

H. Ochs, J. Butel, A. Blancher, 2007 .

SCID and Other Inborn Errors of Immunity with Low TRECs — the Brazilian Experience

J. Walter, H. Ochs, T. Torgerson, 2022, Journal of Clinical Immunology.

Epstein-Barr virus-induced diseases in boys with the X-linked lymphoproliferative syndrome (XLP): update on studies of the registry.

H. Ochs, G. Vawter, J. Greally, 1982, The American journal of medicine.

Home self-administration of intravenous immunoglobulin therapy in children.

R. Kobayashi, H. Ochs, N. Lee, 1990, Pediatrics.

A Registry Study of 240 Patients with X-Linked Agammaglobulinemia Living in the USA

C. Cunningham-Rundles, H. Ochs, K. Sullivan, 2023, Journal of Clinical Immunology.

Primary Immune Deficiency Treatment Consortium (PIDTC) report.

M. van der Burg, L. Notarangelo, H. Bobby Gaspar, 2014, The Journal of allergy and clinical immunology.

Impaired induction of DNA lesions during immunoglobulin class-switch recombination in humans influences end-joining repair

H. Ochs, A. Durandy, K. Imai, 2010, Proceedings of the National Academy of Sciences.

TH17 cells and regulatory T cells in primary immunodeficiency diseases.

H. Ochs, T. Torgerson, M. Oukka, 2009, The Journal of allergy and clinical immunology.

Decreased somatic hypermutation induces an impaired peripheral B cell tolerance checkpoint.

M. van der Burg, L. Notarangelo, J. Walter, 2016, The Journal of clinical investigation.

Combined De-Novo Mutation and Non-Random X-Chromosome Inactivation Causing Wiskott-Aldrich Syndrome in a Female with Thrombocytopenia

S. Scherer, H. Ochs, T. Torgerson, 2013, Journal of Clinical Immunology.

Activation-Induced Cytidine Deaminase Expression in Human B Cell Precursors Is Essential for Central B Cell Tolerance.

L. Notarangelo, J. Walter, W. Al-Herz, 2015, Immunity.

DOCK8 functions as an adaptor that links Toll-like receptor–MyD88 signaling to B cell activation

Douglas R. McDonald, L. Notarangelo, A. Plebani, 2012, Nature Immunology.

Psychosocial stress moderates the relationship of cancer history with natural killer cell activity

H. Ochs, K. Syrjala, I. Siegler, 1998, Annals of behavioral medicine : a publication of the Society of Behavioral Medicine.

Immunoglobulin class responsible for gonococcal bactericidal activity of normal human sera.

G. Schoolnik, H. Ochs, T. Buchanan, 1979, Journal of immunology.

Transient immunomodulation with anti-CD40 ligand antibody and CTLA4Ig enhances persistence and secondary adenovirus-mediated gene transfer into mouse liver.

A. Gown, P. Linsley, M. Kay, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Targeted gene editing restores regulated CD40L function in X-linked hyper-IgM syndrome.

H. Ochs, T. Torgerson, A. Scharenberg, 2016, Blood.

Partial immune reconstitution of X-linked hyper IgM syndrome with recombinant CD40 ligand.

S. Pittaluga, H. Ochs, S. Migueles, 2011, Blood.

Characterization of exogenous type D retrovirus from a fibroma of a macaque with simian AIDS and fibromatosis.

H. Ochs, L. Arthur, C. Tsai, 1984, Science.

X-linked Hyper IgM Syndrome Presenting as Pulmonary Alveolar Proteinosis

H. Ochs, T. Torgerson, J. Verbsky, 2016, Journal of Clinical Immunology.

Immunomodulatory Effects of Mixed Hematopoietic Chimerism: Immune Tolerance in Canine Model of Lung Transplantation

R. Glenny, H. Ochs, R. Storb, 2009, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

Monitoring serum IL-18 levels is useful for treatment of a patient with systemic juvenile idiopathic arthritis complicated by macrophage activation syndrome

H. Ochs, K. Koike, K. Agematsu, 2011, Pediatric rheumatology online journal.

Dovepress Subcutaneous immunoglobulin replacement therapy in the treatment of patients with primary immunodeficiency

H. Ochs, T. Torgerson, S. Skoda-Smith, 2009 .

Dovepress Subcutaneous immunoglobulin replacement therapy in the treatment of patients with primary immunodeficiency

H. Ochs, T. Torgerson, S. Skoda-Smith, 2009 .

Autosomal Dominant Hyper-IgE Syndrome in the USIDNET Registry.

C. Cunningham-Rundles, S. Holland, H. Ochs, 2017, The journal of allergy and clinical immunology. In practice.