K. Muthusamy

发表

Analysis and design of a novel hybrid topology for power quality improvement using multilevel inverter fed induction motor by reducing vibration for textile wastewater treatment applications

Vijayachitra Senniappan, Sathish Kumar Shanmugam, Karthikeyan Muthusamy, 2019, Journal of Vibroengineering.

E-Pharmacophore mapping and docking studies on Vitamin D receptor (VDR)

K. Muthusamy, S. Nagamani, C. Kesavan, 2012, Bioinformation.

Ligand-based Pharmacophore Modeling; Atom-based 3D-QSAR Analysis and Molecular Docking Studies of Phosphoinositide-Dependent Kinase-1 Inhibitors

K. Muthusamy, S. Nagamani, P. Kirubakaran, 2012, Indian journal of pharmaceutical sciences.

Vitamin D receptor (VDR) non-synonymous single nucleotide polymorphisms (nsSNPs) affect the calcitriol drug response - A theoretical insight.

K. Muthusamy, S. Nagamani, 2018, Journal of molecular graphics & modelling.

Combined sequence and sequence-structure based methods for analyzing FGF23, CYP24A1 and VDR genes

K. Muthusamy, S. Nagamani, K. D. Singh, 2016, Meta gene.

Antidiabetic, antihyperlipidaemic, and antioxidant activity of Syzygium densiflorum fruits in streptozotocin and nicotinamide-induced diabetic rats

K. Muthusamy, D. Chellappan, Gopinath Krishnasamy, 2016, Pharmaceutical biology.

Missense variants in the voltage sensing and pore domain of KCNH5 cause neurodevelopmental phenotypes including epilepsy

S. Ellard, K. Muthusamy, R. Møller, 2022, medRxiv.

In silico genome analysis and drug efficacy test of influenza A virus (H1N1) 2009

K. Muthusamy, K. D. Singh, 2009, Indian Journal of Microbiology.

Computational and Pharmacogenomics Insights on Hypertension Treatment: Rational Drug Design and Optimization Strategies.

K. Muthusamy, R. Kukreti, Jung-Kul Lee, 2019, Current drug targets.

E-pharmacophore filtering and molecular dynamics simulation studies in the discovery of potent drug-like molecules for chronic kidney disease

K. Muthusamy, S. Nagamani, J. Marshal, 2016, Journal of biomolecular structure & dynamics.

Molecular modeling, quantum polarized ligand docking and structure-based 3D-QSAR analysis of the imidazole series as dual AT1 and ETA receptor antagonists

K. Muthusamy, K. D. Singh, 2013, Acta Pharmacologica Sinica.

Chromatographic Detection of Antibacterial Antibiotics from Pseudomonas fluorescens (TNAU PF1) and Their Effect on Bacterial Wilt Pathogen Ralstonia solanacearum (KK2)

K. Muthusamy, Shiva Nagendran, Paranidharan Vaikuntavasan, 2019, International Research Journal of Pure and Applied Chemistry.

Drug Targets and Therapeutic Approaches of Alzheimer ’ s Disease

K. Muthusamy, Lakshmanan Loganathan, E. Palanivel, 2018 .

Pharmacophore modeling, 3D-QSAR, and molecular docking study on naphthyridine derivatives as inhibitors of 3-phosphoinositide-dependent protein kinase-1

K. Muthusamy, S. Nagamani, P. Kirubakaran, 2013, Medicinal Chemistry Research.

Computational study on cross-talking cancer signalling mechanism of ring finger protein 146, AXIN and Tankyrase protein complex

K. Muthusamy, Keerthana Natarajan, Lakshmanan Loganathan, 2019, Journal of biomolecular structure & dynamics.

Association of Vitamin-D and VDR with ACE2 Modulates the Severity in COVID-19

K. Muthusamy, A. Al‐Sehemi, M. Pannipara, 2021 .

The Binding Mode Prediction and Similar Ligand Potency in the Active Site of Vitamin D Receptor with QM/MM Interaction, MESP, and MD Simulation

K. Muthusamy, Nagamani Selvaraman, S. K. Selvam, 2016, Chemical biology & drug design.

In silico drug designing for the identification of promising antagonist hit molecules against bradykinin receptor

K. Muthusamy, Lakshmanan Loganathan, Manikandan Selvaraj, 2021 .

Inhibitory potential of Hydroxychavicol on Ehrlich ascites carcinoma model and in silico interaction on cancer targets

K. Muthusamy, S. Sivaramakrishnan, K. Premkumar, 2018, Natural product research.

Computational prediction of immunodominant antigenic regions & potential protective epitopes for dengue vaccination

K. Muthusamy, Krishnasamy Gopinath, Dharmalingam Nandhini, 2016, The Indian journal of medical research.

A PILOT STUDY ON THE PREVALENCE AND ASSOCIATION OF GPRC6A SINGLE NUCLEOTIDE POLYMORPHISMS IN SOUTH INDIAN PATIENTS WITH METABOLIC SYNDROME, METABOLIC SYNDROME AND INFERTILITY

Loganathan, K. Muthusamy, R. Gomathinayagam, 2019 .

Mitochondrial ATP6 and ND3 genes are associated with type 2 diabetic peripheral neuropathy.

K. Muthusamy, K. Matrougui, S. Elango, 2022, Diabetes & metabolic syndrome.

Expressing OsiSAP8, a Zinc-Finger Associated Protein Gene, Mitigates Stress Dynamics in Existing Elite Rice Varieties of the ‘Green Revolution’

K. Muthusamy, M. Prasanth, K. Balamurugan, 2022, Sustainability.

In vitro evaluation of antioxidant and antidiabetic activities of Syzygium densiflorum fruits

K. Muthusamy, Gopinath Krishnasamy, 2015 .

Pharmacophore modeling, 3D-QSAR, and molecular docking study on naphthyridine derivatives as inhibitors of 3-phosphoinositide-dependent protein kinase-1

K. Muthusamy, S. Nagamani, P. Kirubakaran, 2013, Medicinal Chemistry Research.

Isolation and characterization of bioactive compounds of Clematis gouriana Roxb. ex DC against snake venom phospholipase A2 (PLA2) computational and in vitro insights

K. Muthusamy, T. Sivaraman, S. Nagarajan, 2017, Journal of Biomolecular Structure and Dynamics.

Theoretical studies on benzimidazole derivatives as E. coli biotin carboxylase inhibitors

K. Muthusamy, S. Nagamani, P. Kirubakaran, 2012, Medicinal Chemistry Research.

Plant Isoquinoline Alkaloid Berberine Exhibits Chromatin Remodeling by Modulation of Histone Deacetylase To Induce Growth Arrest and Apoptosis in the A549 Cell Line.

K. Muthusamy, R. Sankar, S. Rajasekaran, 2016, Journal of agricultural and food chemistry.

Homology modeling, molecular dynamics, and molecular docking studies of Trichomonas vaginalis carbamate kinase

K. Muthusamy, S. Nagamani, P. Kirubakaran, 2011, Medicinal Chemistry Research.

Tannic acid attenuates TGF‐β1‐induced epithelial‐to‐mesenchymal transition by effectively intervening TGF‐β signaling in lung epithelial cells

K. Muthusamy, S. Rajasekaran, Venkateshwaran Krishnaswami, 2018, Journal of cellular physiology.

Introduction of Stereo Chemical Constraints into β-Amino Acid Residues

K. Muthusamy, Sathishkumar Chinnasamy, Selvakkumar Chinnasamy, 2016 .

First Report of Clonostachys rosea as a Mycoparasite on Sclerotinia sclerotiorum Causing Head Rot of Cabbage in India

K. Muthusamy, B. Prithiviraj, Pugalendhi Lakshmanan, 2023, Plants.

Exploring the Carbamazepine Interaction with Human Pregnane X Receptor and Effect on ABCC2 Using in Vitro and in Silico Approach

K. Muthusamy, R. Kukreti, A. Singhal, 2017, Pharmaceutical Research.

In silico identification and screening of CYP24A1 inhibitors: 3D QSAR pharmacophore mapping and molecular dynamics analysis

K. Muthusamy, Jung-Kul Lee, Gopinath Krishnasamy, 2019, Journal of biomolecular structure & dynamics.

Immunohistochemical staining for adipophilin, perilipin and TIP47

K. Muthusamy, F. Roberts, F. Roberts, 2006, Journal of Clinical Pathology.

Myocilin mutations among POAG patients from two populations of Tamil Nadu, South India, a comparative analysis

K. Muthusamy, A. Balakrishnan, P. Arumugam, 2011, Molecular vision.

Homology modeling, molecular dynamics, e-pharmacophore mapping and docking study of Chikungunya virus nsP2 protease

Shanthi Nagarajan, Jeyaraman Jeyakanthan, Kh. Dhanachandra Singh, 2011, Journal of Molecular Modeling.

Overcoming NADPH product inhibition improves D-sorbitol conversion to L-sorbose

K. Muthusamy, J. Sohng, V. Kalia, 2019, Scientific Reports.

Regulatory pathways of colorectal cancer and their synergistic cross-talk mechanism

K. Muthusamy, M. Jothimani, L. Loganathan, 2020 .

Tannic acid prevents macrophage-induced pro-fibrotic response in lung epithelial cells via suppressing TLR4-mediated macrophage polarization

K. Muthusamy, S. Rajasekaran, S. Mahapatra, 2019, Inflammation Research.

Molecular insights on TNKS1/TNKS2 and inhibitor-IWR1 interactions.

K. Muthusamy, S. Cho, G. Kothandan, 2014, Molecular bioSystems.

Sighting of tankyrase inhibitors by structure- and ligand-based screening and in vitro approach.

K. Muthusamy, K. Premkumar, P. Kirubakaran, 2014, Molecular bioSystems.

Insights into Structural Modifications of Valproic Acid and Their Pharmacological Profile

Y. Hasija, K. Muthusamy, R. Kukreti, 2021, Molecules.

ASSOCIATION OF PLEKHA7 (rs11024074) AND ULK4 (rs1052501) GENE POLYMORPHISM WITH ESSENTIAL HYPERTENSION RISK AMONG SOUTH INDIAN POPULATION

K. Muthusamy, S. Venkatramani, S. Thiagarajan, 2018 .

Genetic polymorphisms of EGF 5'-UTR and NAT2 857G/A associated with glioma in a case control study of Malaysian patients.

K. Muthusamy, K. Chua, V. Waran, 2012, Genetics and molecular research : GMR.

Vitamin D Receptor Genetic Variants among CKD Patients of South Indian Population

K. Muthusamy, R. Kukreti, S. Nagamani, 2018 .

Zn2+ ion of the snake venom metalloproteinase (SVMP) plays a critical role in ligand binding: a molecular dynamics simulation study

K. Muthusamy, S. Nagamani, Sathishkumar Chinnasamy, 2015 .

Gender-specific Association of ATP2B1 (rs2681472) Gene Polymorphism with Essential Hypertension in South Indian Population

K. Muthusamy, S. Venkatramani, S. Thiagarajan, 2017 .

Systemic induction of defense-related genes in tomato by Pseudomonas fluorescens suppresses bacterial wilt disease incited by Ralstonia solanacearum

K. Muthusamy, Shiva Nagendran, Paranidharan Vaikuntavasan, 2019 .

A computational study on role of 6-(hydroxymethyl)-3-[3,4,5-trihydroxy-6-[(3,4,5-trihydroxyoxan-2-yl)oxymethyl]oxan-2-yl]oxyoxane-2,4,5-triol in the regulation of blood glucose level

Karthikeyan Muthusamy, K. Muthusamy, Gopinath Krishnasamy, 2016, Journal of biomolecular structure & dynamics.

Computational Study on the Inhibitory Effect of Natural Compounds against the SARS-CoV-2 Proteins

K. Muthusamy, A. Al‐Sehemi, O. Pentikäinen, 2022, Bioinorganic chemistry and applications.

Design, synthesis, and characterization of α, β‐unsaturated carboxylic acid, and its urea based derivatives that explores novel epigenetic modulators in human non‐small cell lung cancer A549 cell line

K. Muthusamy, R. Chidambaram, Ravikumar Vilwanathan, 2018, Journal of cellular physiology.

Virtual screening assisted discovery of novel natural products to inhibit the catalytic mechanism of Mycobacterium tuberculosis InhA

K. Muthusamy, Manikandan Jayaraman, K. Ramadas, 2021 .

Structural insights on vitamin D receptor and screening of new potent agonist molecules: structure and ligand-based approach

K. Muthusamy, C. Kesavan, J. M. Jayaraj, 2020, Journal of biomolecular structure & dynamics.

Computational and in vitro insights on snake venom phospholipase A2 inhibitor of phytocompound ikshusterol3-O-glucoside of Clematis gouriana Roxb. ex DC.

K. Muthusamy, T. Sivaraman, S. Nagarajan, 2018, Journal of biomolecular structure & dynamics.

In silico insights on tankyrase protein: A potential target for colorectal cancer

K. Muthusamy, L. Loganathan, J. M. Jayaraj, 2018, Journal of biomolecular structure & dynamics.

Structural and functional insights on vitamin D receptor and CYP24A1 deleterious single nucleotide polymorphisms: A computational and pharmacogenomics perpetual approach

K. Muthusamy, A. Alhazmi, B. Kuriakose, 2021, Cell biochemistry and function.

Overcoming NADPH product inhibition improves D-sorbitol conversion to L-sorbose

K. Muthusamy, J. Sohng, In-Won Kim, 2019, Scientific Reports.

Evaluation of Anti-Pyretic Effect of Trichosanthes tricuspidata Linn on Albino Rats

K. Muthusamy, K. Manivel, 2011 .

Targeting Renin Receptor for the inhibition of Renin Angiotensin Aldosterone system: An alternative approach through in silico drug discovery

K. Muthusamy, Beena Briget Kuriakose, Eva Lobelle Sampayan, 2021, Computational and Theoretical Chemistry.

Role of Hydrophobic Patch in LRP6: A Promising Drug Target for Alzheimer's disease

K. Muthusamy, S. Nagamani, S. Prasad, 2016 .

Identification of potent inhibitors against snake venom metalloproteinase (SVMP) using molecular docking and molecular dynamics studies

K. Muthusamy, S. Nagamani, Sathishkumar Chinnasamy, 2015, Journal of biomolecular structure & dynamics.

TRAF2 and NCK-interacting kinase inhibitors for colorectal cancer; in vitro and theoretical validations.

K. Muthusamy, M. Alagumuthu, Nargis Begum Tajuddin, 2020, ACS combinatorial science.

High throughput virtual screening and E-pharmacophore filtering in the discovery of new BACE-1 inhibitors

K. Muthusamy, S. Nagamani, K. D. Singh, 2013, Interdisciplinary Sciences: Computational Life Sciences.

Mechanistic insights into the role of vitamin D and computational identification of potential lead compounds for Parkinson's disease

K. Muthusamy, B. Kuriakose, Jayaraj John Marshal, 2023, Journal of cellular biochemistry.

Design and synthesis of imidazole based zinc binding groups as novel small molecule inhibitors targeting Histone deacetylase enzymes in lung cancer

K. Muthusamy, S. Kandasamy, K. Srinivasan, 2020 .

Homology modeling, molecular dynamics, and molecular docking studies of Trichomonas vaginalis carbamate kinase

K. Muthusamy, S. Nagamani, P. Kirubakaran, 2012, Medicinal Chemistry Research.

Identification of novel small molecules that bind to the loop2 region of sclerostin - an in silico computational analysis.

K. Muthusamy, S. Nagamani, C. Kesavan, 2016, Physiological research.

Computational prediction of small molecules with predicted binding to FGFR3 and testing biological effects in bone cells

K. Muthusamy, S. Mohan, S. Nagamani, 2021, Experimental biology and medicine.

A theoretical insight to understand the molecular mechanism of dual target ligand CTA-018 in the chronic kidney disease pathogenesis

K. Muthusamy, S. Nagamani, 2018, PloS one.

Role of deleterious nsSNPs of klotho protein and their drug response: a computational mechanical insights.

K. Muthusamy, J. Jayaraj, 2023, Journal of biomolecular structure & dynamics.

Mechanistic insights on nsSNPs on binding site of renin and cytochrome P450 proteins: A computational perceptual study for pharmacogenomics evaluation

K. Muthusamy, B. Kuriakose, Sakeena Mushfiq, 2021, Journal of cellular biochemistry.

In silico studies on marine actinomycetes as potential inhibitors for Glioblastoma multiforme

Selvaraman Nagamani, Palani Kirubakaran, Roopa Kothapalli, 2011, Bioinformation.

Structural exploration of common pharmacophore based berberine derivatives as novel histone deacetylase inhibitor targeting HDACs enzymes

K. Muthusamy, S. Kandasamy, Ashokkumar Sekar, 2022, Journal of biomolecular structure & dynamics.

High throughput virtual screening and E-pharmacophore filtering in the discovery of new BACE-1 inhibitors

K. Muthusamy, S. Nagamani, Gopinath Krishnasamy, 2013, Interdisciplinary Sciences: Computational Life Sciences.

Gene signals and SNPs associated with Parkinson’s disease: A nutrigenomics and computational prospective insights

K. Muthusamy, N. M. Prabhu, B. Kuriakose, 2023, Neuroscience.

Nanopeptides: Non-Covalent Interactions in Chemistry and Biological Functions

K. Muthusamy, Sathishkumar Chinnasamy, C. Selvakkumar, 2016 .