Yogesh Sabnis

发表

The Promise of AI for DILI Prediction

Jiye Shi, Sepp Hochreiter, Günter Klambauer, 2021, Frontiers in Artificial Intelligence.

Identification of novel parasitic cysteine protease inhibitors using virtual screening. 1. The ChemBridge database.

Jiri Gut, Prashant V Desai, Mitchell Avery, 2004, Journal of medicinal chemistry.

Identification of Type‐II Inhibitors Using Kinase Structures

R. Kurumbail, Yogesh Sabnis, Chris Phillips, 2012, Chemical biology & drug design.

Investigation of the effect of molecular properties on the binding kinetics of a ligand to its biological target

Nichola L. Davies, Yogesh Sabnis, P. Driscoll, 2012 .

Structure-based approach to falcipain-2 inhibitors: synthesis and biological evaluation of 1,6,7-trisubstituted dihydroisoquinolines and isoquinolines.

Sanjay Batra, S. Batra, P. Rosenthal, 2003, Bioorganic & medicinal chemistry.

Transformation of lactone to lactam in sarcophine and antimalarial activity of the resulting N-substituted azasarcophines

Yogesh Sabnis, M. Hamann, K. Orabi, 2002 .

Developing irreversible inhibitors of the protein kinase cysteinome.

Nathanael S Gray, Qingsong Liu, Zheng Zhao, 2013, Chemistry & biology.

Evaluation of a diverse set of potential P1 carboxylic acid bioisosteres in hepatitis C virus NS3 protease inhibitors.

Yogesh Sabnis, A. Sandström, U. Danielson, 2007, Bioorganic & medicinal chemistry.

Exploration of acyl sulfonamides as carboxylic acid replacements in protease inhibitors of the hepatitis C virus full-length NS3.

A. Hallberg, Yogesh Sabnis, A. Johansson, 2006, Bioorganic & medicinal chemistry.

Phenylglycine as a novel P2 scaffold in hepatitis C virus NS3 protease inhibitors.

Yogesh Sabnis, G. Lindeberg, A. Karlén, 2007, Bioorganic & medicinal chemistry.

Interaction of artemisinin and its related compounds with hydroxypropyl-beta-cyclodextrin in solution state: experimental and molecular-modeling studies.

Yogesh Sabnis, B. Avery, M. Avery, 2003, Journal of pharmaceutical sciences.

A new structural theme in C2-symmetric HIV-1 protease inhibitors: ortho-substituted P1/P1' side chains.

L. Vrang, B. Samuelsson, A. Hallberg, 2006, Bioorganic & medicinal chemistry.

Design and Synthesis of a Pan-Janus Kinase Inhibitor Clinical Candidate (PF-06263276) Suitable for Inhaled and Topical Delivery for the Treatment of Inflammatory Diseases of the Lungs and Skin.

Yogesh Sabnis, J. Chrencik, G. Whitlock, 2017, Journal of medicinal chemistry.

In silico approaches in organ toxicity hazard assessment: current status and future needs in predicting liver toxicity.

Daniel P. Russo, Marlene T. Kim, Vinicius M. Alves, 2021, Computational toxicology.

Is it possible to increase hit rates in structure-based virtual screening by pharmacophore filtering? An investigation of the advantages and pitfalls of post-filtering.

Anders Karlén, Magnus Lundborg, Daniel Muthas, 2008, Journal of molecular graphics & modelling.

Design, Synthesis and Evaluation of Trisubstituted Thiazoles Targeting Plasmodium Falciparum Cysteine Proteases

Mitchell A. Avery, Prashant V. Desai, Philip J. Rosenthal, 2005, Medicinal Chemistry Research.

In silico approaches in organ toxicity hazard assessment: Current status and future needs for predicting heart, kidney and lung toxicities.

Daniel P. Russo, Vinicius M. Alves, G. Myatt, 2021, Computational toxicology.

Structure-activity relationships of the antimalarial agent artemisinin. 6. The development of predictive in vitro potency models using CoMFA and HQSAR methodologies.

Carlos R Rodrigues, F. Cohen, Yogesh Sabnis, 2002, Journal of medicinal chemistry.

Homology Modeling of Falcipain-2: Validation, De Novo Ligand Design and Synthesis of Novel Inhibitors

Prashant Desai, Yogesh Sabnis, P. Rosenthal, 2002, Journal of biomolecular structure & dynamics.

Synthesis, biological evaluation, and modeling studies of inhibitors aimed at the malarial proteases plasmepsins I and II.

D. Nöteberg, Elizabeth Hamelink, L. Vrang, 2005, Bioorganic & medicinal chemistry.

Discovery and synthesis of a new class of opioid ligand having a 3-azabicyclo[3.1.0]hexane core. An example of a 'magic methyl' giving a 35-fold improvement in binding.

Yogesh Sabnis, A. Pettman, N. Feeder, 2011, Bioorganic & medicinal chemistry letters.

Probing the structure of falcipain‐3, a cysteine protease from Plasmodium falciparum: Comparative protein modeling and docking studies

Prashant V Desai, Yogesh Sabnis, M. Avery, 2003, Protein science : a publication of the Protein Society.