P. Schimmel

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Evidence for dispensable sequences inserted into a nucleotide fold.

R. Starzyk, T. Webster, P. Schimmel, 1987, Science.

Getting tRNA synthetases into the nucleus.

P. Schimmel, C. Wang, 1999, Trends in biochemical sciences.

Identification of the tRNA-Dihydrouridine Synthase Family*

V. de Crécy-Lagard, P. Schimmel, Reid C. Johnson, 2002, The Journal of Biological Chemistry.

Two mutations in the dispensable part of alanine tRNA synthetase which affect the catalytic activity.

L. Regan, P. Schimmel, M. Jasin, 1985, The Journal of biological chemistry.

Conformational energies and configurational statistics of copolypeptides containing L-proline.

P J Flory, P. Schimmel, P. Flory, 1968, Journal of molecular biology.

RNA pseudoknots that interact with components of the translation apparatus

P. Schimmel, 1989, Cell.

Two distinct cytokines released from a human aminoacyl-tRNA synthetase.

P. Schimmel, K. Wakasugi, 1999, Science.

Highly Differentiated Motifs Responsible for Two Cytokine Activities of a Split Human tRNA Synthetase*

P. Schimmel, K. Wakasugi, 1999, The Journal of Biological Chemistry.

Induction of Angiogenesis by a Fragment of Human Tyrosyl-tRNA Synthetase*

P. Schimmel, K. Ewalt, D. Cheresh, 2002, The Journal of Biological Chemistry.

VE-cadherin Links tRNA Synthetase Cytokine to Anti-angiogenic Function*

J. Reader, P. Schimmel, K. Ewalt, 2005, Journal of Biological Chemistry.

Editing-defective tRNA synthetase causes protein misfolding and neurodegeneration

S. Ackerman, P. Schimmel, M. Davisson, 2006, Nature.

Aminoacyl tRNA synthetases and their connections to disease

Sunghoon Kim, P. Schimmel, S. Park, 2008, Proceedings of the National Academy of Sciences.

The novel fragment of tyrosyl tRNA synthetase, mini‐ TyrRS, is secreted to induce an angiogenic response in endothelial cells

J. Reader, P. Schimmel, K. Ewalt, 2008, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Biologically active fragment of a human tRNA synthetase inhibits fluid shear stress-activated responses of endothelial cells

J. Reader, P. Schimmel, K. Ewalt, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Functional assembly of a randomly cleaved protein.

P. Schimmel, K. Shiba, K Shiba, 1992, Proceedings of the National Academy of Sciences of the United States of America.

Transfer RNA-dependent translocation of misactivated amino acids to prevent errors in protein synthesis.

P. Schimmel, T. Nomanbhoy, P Schimmel, 1999, Molecular cell.

Functional analysis of peptide motif for RNA microhelix binding suggests new family of RNA‐binding domains

N. Sardesai, P. Schimmel, L. R. de Pouplana, 1998, The EMBO journal.

Assembly of a catalytic unit for RNA microhelix aminoacylation using nonspecific RNA binding domains.

P. Schimmel, J. Chihade, 1999, Proceedings of the National Academy of Sciences of the United States of America.

Specific atomic groups and RNA helix geometry in acceptor stem recognition by a tRNA synthetase.

P. Schimmel, K. Musier-Forsyth, P. Beuning, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Transfer ribonucleic acid synthetase catalyzed deacylation of aminoacyl transfer ribonucleic acid in the absence of adenosine monophosphate and pyrophosphate.

P. Schimmel, A. Schreier, 1972, Biochemistry.

Synthesis of two polypeptide subunits of an aminoacyl tRNA synthetase as a single polypeptide chain.

P. Schimmel, T. Keng, 1983, Journal of biomolecular structure & dynamics.

A single base pair affects binding and catalytic parameters in the molecular recognition of a transfer RNA.

S. Park, P. Schimmel, Ya-Ming Hou, 1989, Biochemistry.

Deletions in the large (beta) subunit of a hetero-oligomeric aminoacyl-tRNA synthetase.

P. Schimmel, M. Toth, 1990, The Journal of biological chemistry.

Dissection of a class II tRNA synthetase: determinants for minihelix recognition are tightly associated with domain for amino acid activation.

P. Schimmel, D. Buechter, 1993, Biochemistry.

Molecular dissection of a transfer RNA and the basis for its identity.

C. Francklyn, P. Schimmel, Y. Hou, 1989, Trends in biochemical sciences.

Detection of leucine-independent DNA site occupancy of the yeast Leu3p transcriptional activator in vivo

P. Schimmel, C. Kirkpatrick, Paul Schimmel, 1995, Molecular and cellular biology.

Fragile T-stem in Disease-associated Human Mitochondrial tRNA Sensitizes Structure to Local and Distant Mutations*

P. Schimmel, S. Kelley, S. Steinberg, 2001, The Journal of Biological Chemistry.

A simple structural feature is a major determinant of the identity of a transfer RNA

Paul Schimmel, P. Schimmel, Ya-Ming Hou, 1988, Nature.

Structural analyses clarify the complex control of mistranslation by tRNA synthetases.

P. Schimmel, M. Guo, Min Guo, 2012, Current opinion in structural biology.

Mistranslation and its control by tRNA synthetases

P. Schimmel, 2011, Philosophical Transactions of the Royal Society B: Biological Sciences.

Cell growth inhibition by sequence‐specific RNA minihelices.

P. Schimmel, D. Hipps, 1995, The EMBO journal.

Charging of RNA Microhelices and Decoding Genetic Information: Evaluation of Functional Coupling Between Distal Parts of a tRNA Structure

P. Schimmel, 1993 .

Triple aminoacylation specificity of a chimerized transfer RNA.

P. Schimmel, C. Florentz, R. Giegé, 1993, Biochemistry.

A metal‐binding motif implicated in RNA recognition by an aminoacyl‐tRNA synthetase and by a retroviral gene product

P. Schimmel, W. Miller, Paul Schimmel, 1992, Molecular microbiology.

A single base pair dominates over the novel identity of an Escherichia coli tyrosine tRNA in Saccharomyces cerevisiae

P. Schimmel, V. Trézéguet, H. Edwards, 1991 .

Evidence for a "cysteine-histidine box" metal-binding site in an Escherichia coli aminoacyl-tRNA synthetase.

P. Schimmel, W. Miller, K. A. Hill, 1991, Biochemistry.

A single base pair dominates over the novel identity of an Escherichia coli tyrosine tRNA in Saccharomyces cerevisiae.

P. Schimmel, V. Trézéguet, H. Edwards, 1991, Molecular and cellular biology.

A bacterial amber suppressor in Saccharomyces cerevisiae is selectively recognized by a bacterial aminoacyl-tRNA synthetase

P. Schimmel, H. Edwards, 1990 .

Evidence that a major determinant for the identity of a transfer RNA is conserved in evolution.

P. Schimmel, Y. Hou, 1989, Biochemistry.

Modeling with in vitro kinetic parameters for the elaboration of transfer RNA identity in vivo.

P. Schimmel, Y. Hou, 1989, Biochemistry.

Structural organization of complexes of transfer RNAs with aminoacyl transfer RNA synthetases.

A. Rich, P. Schimmel, 1977, Nucleic acids research.

Tripartite functional assembly of a large class I aminoacyl tRNA synthetase.

P. Schimmel, K. Shiba, 1992, The Journal of biological chemistry.

A fragment of human TrpRS as a potent antagonist of ocular angiogenesis

P. Schimmel, K. Ewalt, D. Cheresh, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Sequence determination and modeling of structural motifs for the smallest monomeric aminoacyl-tRNA synthetase.

P. Schimmel, C. Mottes, K. Shiba, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Zinc-Independent Folate Biosynthesis: Genetic, Biochemical, and Structural Investigations Reveal New Metal Dependence for GTP Cyclohydrolase IB

Scott E. Gabriel, K. Shah, V. de Crécy-Lagard, 2009, Journal of bacteriology.

Structure-Based Phylogeny of Class IIa tRNA Synthetases in Relation to an Unusual Biochemistry

James R. Brown, P. Schimmel, L. Ribas de Pouplana, 2001, Journal of Molecular Evolution.

Activation of microhelix charging by localized helix destabilization.

P. Schimmel, R. Alexander, B. Nordin, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Human Lysyl-tRNA Synthetase Accepts Nucleotide 73 Variants and Rescues Escherichia coli Double-defective Mutant*

T. Noda, P. Schimmel, K. Musier-Forsyth, 1997, The Journal of Biological Chemistry.

Functional dissection of a predicted class-defining motif in a class II tRNA synthetase of unknown structure.

P. Schimmel, D. Buechter, M. Davis, 1994, Biochemistry.

Region of a conserved sequence motif in a class II tRNA synthetase needed for transfer of an activated amino acid to an RNA substrate.

P. Schimmel, K. Musier-Forsyth, J. P. Shi, 1994, Biochemistry.

Crystallization of a small fragment of an aminoacyl tRNA synthetase.

L. Regan, A. Rich, P. Schimmel, 1988, Journal of molecular biology.

Plasticity of Recognition of the 3′-End of Mischarged tRNA by Class I Aminoacyl-tRNA Synthetases*

P. Schimmel, B. Nordin, 2002, The Journal of Biological Chemistry.

Formation of two classes of tRNA synthetases in relation to editing functions and genetic code.

P. Schimmel, L. Ribas de Pouplana, L. R. Pouplana, 2001, Cold Spring Harbor symposia on quantitative biology.

Mutational analysis suggests the same design for editing activities of two tRNA synthetases.

P. Schimmel, L. Lin, L. Lin, 1996, Biochemistry.

Nucleotide determinants for tRNA-dependent amino acid discrimination by a class I tRNA synthetase.

P. Schimmel, B. Nordin, M. Farrow, 1999, Biochemistry.

Structural relationships and the classification of aminoacyl-tRNA synthetases.

P. Schimmel, J. Burbaum, Paul Schimmel, 1991, The Journal of biological chemistry.

Rabbit muscle creatine kinase: genomic cloning, sequencing, and analysis of upstream sequences important for expression in myocytes.

P. Schimmel, T. Yi, K. Walsh, 1991, Nucleic acids research.

Rationale for engineering an enzyme by introducing a mutation that compensates for a deletion.

L. Regan, P. Schimmel, L. Buxbaum, 1988, The Journal of biological chemistry.

A covalent adduct between the uracil ring and the active site of an aminoacyl tRNA synthetase

R. Starzyk, P. Schimmel, S. W. Koontz, 1982, Nature.

Binding of complementary oligonucleotides to free and aminoacyl transfer ribonucleic acid synthetase bound transfer ribonucleic acid.

O. Uhlenbeck, P. Schimmel, J. B. Lewis, 1972, Biochemistry.

Zinc-dependent cell growth conferred by mutant tRNA synthetase.

P. Schimmel, J. Landro, 1994, The Journal of biological chemistry.

Metal-binding site in a class I tRNA synthetase localized to a cysteine cluster inserted into nucleotide-binding fold.

P. Schimmel, J. Landro, 1993, Proceedings of the National Academy of Sciences of the United States of America.

Breaking sieve for steric exclusion of a noncognate amino acid from active site of a tRNA synthetase.

P. Schimmel, M. Swairjo, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Human glycyl-tRNA synthetase. Wide divergence of primary structure from bacterial counterpart and species-specific aminoacylation.

T. Noda, P. Schimmel, H. Motegi, 1994, The Journal of biological chemistry.

Active site of an aminoacyl-tRNA synthetase dissected by energy-transfer-dependent fluorescence.

P. Schimmel, T. Nomanbhoy, 2001, Bioorganic & medicinal chemistry letters.

Microarrays of cells expressing de ® ned cDNAs

A. Ortiz, P. Schimmel, B. Mukhopadhyay, 2001 .

Crystallization and preliminary X-ray characterization of the nitrile reductase QueF: a queuosine-biosynthesis enzyme.

V. de Crécy-Lagard, P. Schimmel, M. Swairjo, 2005, Acta crystallographica. Section F, Structural biology and crystallization communications.

Induction of a cellular enzyme for energy metabolism by transforming domains of adenovirus E1a

R. Kingston, P. Schimmel, J. Lillie, 1990, Molecular and cellular biology.

Isolation of a functional human gene for brain creatine kinase.

R. Kingston, P. Schimmel, R. Kaddurah-Daouk, 1988, The Journal of biological chemistry.

Effect of mini-tyrosyl-tRNA synthetase on ischemic angiogenesis, leukocyte recruitment, and vascular permeability.

P. Schimmel, K. Ewalt, J. Faber, 2008, American journal of physiology. Regulatory, integrative and comparative physiology.

Chiral-selective aminoacylation of an RNA minihelix: Mechanistic features and chiral suppression

P. Schimmel, K. Tamura, 2006, Proceedings of the National Academy of Sciences.

DNA-binding site for two skeletal actin promoter factors is important for expression in muscle cells

P. Schimmel, K. Walsh, 1988, Molecular and cellular biology.

Two nuclear factors compete for the skeletal muscle actin promoter.

P. Schimmel, K. Walsh, 1987, The Journal of biological chemistry.

Wide cross-species aminoacyl-tRNA synthetase replacement in vivo: yeast cytoplasmic alanine enzyme replaced by human polymyositis serum antigen.

P. Schimmel, K. Shiba, T. Ripmaster, 1995, Proceedings of the National Academy of Sciences of the United States of America.

Human cytoplasmic isoleucyl-tRNA synthetase: selective divergence of the anticodon-binding domain and acquisition of a new structural unit.

T. Noda, P. Schimmel, K. Shigesada, 1994, Proceedings of the National Academy of Sciences of the United States of America.

Operational RNA code for amino acids: species-specific aminoacylation of minihelices switched by a single nucleotide.

P. Schimmel, K. Shiba, B. Henderson, 1995, Proceedings of the National Academy of Sciences of the United States of America.

Functional expansion of the tRNA world under stress.

P. Schimmel, Xiang-Lei Yang, Xiang-lei Yang, 2011, Molecular cell.

Functional defects of pathogenic human mitochondrial tRNAs related to structural fragility

P. Schimmel, S. Kelley, S. Steinberg, 2000, Nature Structural Biology.

Aminoacyl tRNA synthetases as targets for new antiâ•’infectives

P. Schimmel, J. Tao, Jason E. Hill, 1998 .

Nucleotide sequence of yeast LEU2 shows 5′-noncoding region has sequences cognate to leucine

P. Schimmel, A. Andreadis, G. Kohlhaw, 1982, Cell.

When protein engineering confronts the tRNA world.

D. Söll, P. Schimmel, 1997, Proceedings of the National Academy of Sciences of the United States of America.

A mechanism for reducing entropic cost of induced fit in protein--RNA recognition.

P. Schimmel, S. Kim, L. Ribas de Pouplana, 1996, Biochemistry.

A eubacterial Mycobacterium tuberculosis tRNA synthetase is eukaryote-like and resistant to a eubacterial-specific antisynthetase drug.

P. Schimmel, M. Sassanfar, K. Shiba, 1996, Biochemistry.

Nanosecond relaxation processes of phospholipid bilayers in the transition zone.

P. Schimmel, R. Gamble, 1978, Proceedings of the National Academy of Sciences of the United States of America.

Evidence for a unique first position codon-anticodon mismatch in vivo.

P. Schimmel, E. J. Murgola, M. Toth, 1988, Journal of molecular biology.

Photo-induced joining of a transfer RNA with its cognate aminoacyl-transfer RNA synthetase.

P. Schimmel, H. Schoemaker, 1974, Journal of molecular biology.

Yeast LEU1. Repression of mRNA levels by leucine and relationship of 5'-noncoding region to that of LEU2.

P. Schimmel, Y. Hsu, 1984, The Journal of biological chemistry.

Multiple new genes that determine activity for the first step of leucine biosynthesis in Saccharomyces cerevisiae.

P. Schimmel, P. Drain, 1988, Genetics.

Cloning of GLN4: an essential gene that encodes glutaminyl-tRNA synthetase in Saccharomyces cerevisiae

P. Schimmel, S. Ludmerer, 1985, Journal of bacteriology.

Structural Relationships in Macromolecular Complexes Determined By Photochemical Crosslinking

P. Schimmel, V. Yue, 1977 .

Mechanism of an aminoacyl transfer ribonucleic acid synthetase

P. Schimmel, 1973 .

Dipole moments in relation to configuration of polypeptide chains.

P. Schimmel, P. Flory, 1967, Journal of the American Chemical Society.

Crystallization and preliminary X-ray analysis of a native human tRNA synthetase whose allelic variants are associated with Charcot-Marie-Tooth disease.

P. Schimmel, Xiang-Lei Yang, W. Xie, 2006, Acta crystallographica. Section F, Structural biology and crystallization communications.

Human lysyl-tRNA synthetase is secreted to trigger proinflammatory response

P. Schimmel, 2005 .

A Sephadex dialysis method of determining small molecule-macromolecule binding constants.

P. Schimmel, P. Fasella, G. Hammes, 1965, Biochimica et biophysica acta.

Perfecting the genetic code with an RNP complex.

P. Schimmel, Xiang-Lei Yang, 2006, Structure.

Antisense RNA complementary to 3' coding and noncoding sequences of creatine kinase is a potent inhibitor of translation in vivo.

P. Schimmel, R. Mulligan, J. Ch'ng, 1989, Proceedings of the National Academy of Sciences of the United States of America.

Effects of abnormal base ionizations on Mg2 plus binding to transfer ribonucleic acid as studied by a fluorescent probe.

P. Schimmel, D. C. Lynch, 1974, Biochemistry.

A Bacterial AmberSuppressor inSaccharomyces cerevisiae Is Selectively Recognized byaBacterial Aminoacyl-tRNA Synthetase

P. Schimmel, H. Edwards, 1990 .

An Investigation of Water-Urea and Water-Urea-Polyethylene Glycol Interactions

P. Schimmel, G. Hammes, 1967 .

Nanosecond relaxation processes in aqueous mononucleoside solutions.

P. Schimmel, L. M. Rhodes, 1971, Biochemistry.

Genetic code origins: Experiments and may explain a puzzle

P. Schimmel, L. R. Pouplana, 2016 .

Affinity coelectrophoresis for dissecting protein-RNA domain-domain interactions in a tRNA synthetase system.

P. Schimmel, A. Gale, 1996, Pharmaceutica acta Helvetiae.

Erratum: VE-cadherin links tRNA synthetase cytokine to antiangiogenic function (Journal of Biological Chemistry (2005) 280 (2405-2408))

J. Reader, P. Schimmel, K. Ewalt, 2007 .

Enzymatic aminoacylation of sequence-specific RNA minihelices and hybrid duplexes with methionine.

S. Martinis, P. Schimmel, 1992, Proceedings of the National Academy of Sciences of the United States of America.

Reversal of creatine kinase translational repression by 3' untranslated sequences.

P. Schimmel, J. Ch'ng, E. Holmes, 1990, Science.

Isolated RNA binding domain of a class I tRNA synthetase.

P. Schimmel, A. Gale, 1995, Biochemistry.

Reflections on the 20^ Taniguchi International Symposium - Tracing Biological Evolution in Protein and Gene Structures

P. Schimmel, 2001 .

Tracing Biological Evolution in Protein and Gene Structures: Proceedings of the 20th Taniguchi International Symposium, Division of Biophysics, Held in Nagoya, Japan, 31 October-4 November 1994

P. Schimmel, 郷通子, 1996 .

Base-analog-induced aminoacylation of an RNA helix by a tRNA synthetase

V. Erdmann, P. Schimmel, K. Musier-Forsyth, 1995 .

Evidence for interaction of an aminoacyl transfer RNA synthetase with a region important for the identity of its cognate transfer RNA.

S. Park, P. Schimmel, 1988, The Journal of biological chemistry.

On the rate law and mechanism of the adenosine triphosphate--pyrophosphate isotope exchange reaction of amino acyl transfer ribonucleic acid synthetases.

P. Schimmel, F. Cole, 1970, Biochemistry.

Two classes give lessons about CCA

P. Schimmel, Xiang-Lei Yang, Xiang-lei Yang, 2004, Nature Structural &Molecular Biology.

Interaction of polyamines with fragments and whole molecules of yeast phenylalanine-specific transfer RNA.

P. Schimmel, A. Schreier, 1975, Journal of molecular biology.

15. Aminoacyl-tRNA Synthetases

D. Söll, P. Schimmel, 1974 .

Yeast LEU5 is a PET-like gene that is not essential for leucine biosynthesis

P. Schimmel, P. Drain, 1986, Molecular and General Genetics MGG.

A bacterial amber suppressor in Saccharomyces cerevisiae is selectively recognized by a bacterial aminoacyl-tRNA synthetase

P. Schimmel, H. Edwards, 1990, Molecular and cellular biology.

Gene for yeast glutamine tRNA synthetase encodes a large amino-terminal extension and provides a strong confirmation of the signature sequence for a group of the aminoacyl-tRNA synthetases.

P. Schimmel, S. Ludmerer, 1987, The Journal of biological chemistry.

LEU3 of Saccharomyces cerevisiae encodes a factor for control of RNA levels of a group of leucine-specific genes

P. Schimmel, P. Friden, 1987, Molecular and cellular biology.

Genetic engineering: blessing or curse?

Paul Schimmel, P. Schimmel, 1978, Christianity today.

Incorporation of nonnatural amino acids into proteins.

Paul Schimmel, Tamara L Hendrickson, V. de Crécy-Lagard, 2004, Annual review of biochemistry.

Evidence for distinct locations for metal binding sites in two closely related class I tRNA synthetases.

P. Schimmel, J. Landro, E. Schmidt, 1993, Journal of Biomolecular Structure and Dynamics.

Aminoacyl tRNA synthetases as targets for new anti‐infectives

J Hill, P. Schimmel, J. Tao, 1998, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Polypeptide sequences essential for RNA recognition by an enzyme.

L. Regan, J. Bowie, P. Schimmel, 1987, Science.

2 Rapid Reactions and Transient States

P. Schimmel, G. Hammes, 1970 .

In Vitro Studies of Photochemically Cross-Linked Protein-Nucleic Acid Complexes. Determination of Cross-Linked Regions and Structural Relationships in Specific Complexes

P. Schimmel, H. Schoemaker, G. Budzik, 1976 .

Intron locations and functional deletions in relation to the design and evolution of a subgroup of class I tRNA synthetases

P. Schimmel, K. Shiba, A. Shepard, 1992, Protein science : a publication of the Protein Society.

Chiral-Selective Aminoacylation of an RNA Minihelix

Paul Schimmel, Koji Tamura, P. Schimmel, 2004, Science.

Interaction of human hemoglobin with adenine nucleotides.

P. Schimmel, H. H. Lo, 1969, The Journal of biological chemistry.

Three photo-cross-linked complexes of yeast phenylalanine specific transfer ribonucleic acid with aminoacyl transfer ribonucleic acid synthetases.

P. Schimmel, R. Giegé, H. Schoemaker, 1975, The Journal of biological chemistry.

Cooperative binding of magnesium to transfer ribonucleic acid studied by a fluorescent probe.

P. Schimmel, D. C. Lynch, 1974, Biochemistry.

Complementary use of chemical modification and site-directed mutagenesis to probe structure-activity relationships in enzymes.

P. Schimmel, A. Profy, 1988, Progress in nucleic acid research and molecular biology.

Transfer RNA in solution: selected topics.

P. Schimmel, A. Redfield, 1980, Annual review of biophysics and bioengineering.

Dynamics of lysozyme-saccharide interactions.

P. Schimmel, D. Chipman, 1968, The Journal of biological chemistry.

Conformational energy and configurational statistics of poly-L-proline.

P. Schimmel, P. Flory, 1967, Proceedings of the National Academy of Sciences of the United States of America.

Specific sequence homology and three-dimensional structure of an aminoacyl transfer RNA synthetase.

T. Webster, P. Schimmel, G. Mackie, 1984, Science.

RNA tetraloops as minimalist substrates for aminoacylation.

S. Martinis, P. Schimmel, J. P. Shi, 1992, Biochemistry.

Rapid deacylation by isoleucyl transfer ribonucleic acid synthetase of isoleucine-specific transfer ribonucleic acid aminoacylated with valine.

P. Schimmel, P R Schimmel, E W Eldred, 1972, The Journal of biological chemistry.

Investigation of the transfer of amino acid from a transfer ribonucleic acid synthetase-aminoacyl adenylate complex to transfer ribonucleic acid.

P. Schimmel, E. Eldred, 1972, Biochemistry.

Laser cross-linking of protein-nucleic acid complexes

P. Schimmel, G. Budzik, 1991 .

[14] Photo-cross-linking of protein-nucleic acid complexes

P. Schimmel, G. Budzik, 1977 .

Bone marrow–derived stem cells target retinal astrocytes and can promote or inhibit retinal angiogenesis

P. Schimmel, K. Ewalt, A. Otani, 2002, Nature Medicine.

Understanding the recognition of transfer RNAs by aminoacyl transfer RNA synthetases.

P. Schimmel, 1979, Advances in enzymology and related areas of molecular biology.

Effect of aminoacyl transfer RNA synthetases on H-5 exchange of specific pyrimidines in transfer RNAs.

P. Schimmel, H. Schoemaker, 1977, Biochemistry.

Discovery of a Gene Family Critical to Wyosine Base Formation in a Subset of Phenylalanine-specific Transfer RNAs*

V. de Crécy-Lagard, P. Schimmel, W. Waas, 2005, Journal of Biological Chemistry.

Inhibition of an aminoacyl transfer RNA synthetase by a specific trinucleotide derived from the sequence of its cognate transfer RNA.

P. Schimmel, H. Schoemaker, 1977, Biochemistry.

Interaction of manganese with fragments, complementary fragment recombinations, and whole molecules of yeast phenylalanine specific transfer RNA.

P. Schimmel, A. Schreier, A. A. Schreier, 1974, Journal of molecular biology.

Introduction to transfer RNA

A. Rich, P. Schimmel, 1977 .

Role of a tRNA Base Modification and Its Precursors in Frameshifting in Eukaryotes*

P. Schimmel, W. Waas, Z. Druzina, 2007, Journal of Biological Chemistry.

Parameters for the molecular recognition of transfer RNAs.

P. Schimmel, 1989, Biochemistry.

Aminoacylation of RNA minihelices with alanine

Paul Schimmel, C. Francklyn, P. Schimmel, 1989, Nature.

Small RNA Oligonucleotide Substrates for Specific Aminoacylations

S. Martinis, P. Schimmel, 1995 .

Aminoacyl-tRNA synthetases: general features and recognition of transfer RNAs.

D. Söll, P. Schimmel, D Söll, 1979, Annual review of biochemistry.

DYNAMICS OF TAUTOMERIZATION OF FORMYCIN

P. Schimmel, F. Cole, 1978 .

Equilibrium measurements of cognate and noncognate interactions between aminoacyl transfer RNA synthetases and transfer RNA.

P. Schimmel, S. S. Lam, 1975, Biochemistry.

Artificially ambiguous genetic code confers growth yield advantage.

P. Marlière, D. Metzgar, V. de Crécy-Lagard, 2004, Proceedings of the National Academy of Sciences of the United States of America.

A new troponin T and cDNA clones for 13 different muscle proteins, found by shotgun sequencing

W. Herlihy, P. Schimmel, S. Putney, 1983, Nature.

Molecular biology: Genetic code seizes pyrrolysine

P. Schimmel, K. Beebe, 2004, Nature.

Genetic code origins: tRNAs older than their synthetases?

P. Schimmel, R. Turner, B. Steer, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Industry benefits from the public funding of intellectual curiosity

P. Schimmel, 2000, Nature.

The emerging complexity of the tRNA world: mammalian tRNAs beyond protein synthesis

Paul Schimmel, P. Schimmel, 2017, Nature Reviews Molecular Cell Biology.

A human aminoacyl-tRNA synthetase as a regulator of angiogenesis

P. Schimmel, K. Ewalt, D. Cheresh, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Translation of a Yeast Mitochondrial tRNA Synthetase Initiated at Redundant non-AUG Codons*

P. Schimmel, Huei-Lin Tang, L. Yeh, 2004, Journal of Biological Chemistry.

Mutational isolation of a sieve for editing in a transfer RNA synthetase.

P. Schimmel, E. Schmidt, Paul Schimmel, 1994, Science.

Residues in a class I tRNA synthetase which determine selectivity of amino acid recognition in the context of tRNA.

P. Schimmel, P Schimmel, E Schmidt, 1995, Biochemistry.

Dominant lethality by expression of a catalytically inactive class I tRNA synthetase.

P. Schimmel, E. Schmidt, 1993, Proceedings of the National Academy of Sciences of the United States of America.

Evidence from cassette mutagenesis for a structure-function motif in a protein of unknown structure.

P. Schimmel, N. Clarke, D. C. Lien, 1988, Science.

Enzymatic aminoacylation of an eight-base-pair microhelix with histidine.

C. Francklyn, P. Schimmel, 1990, Proceedings of the National Academy of Sciences of the United States of America.

Operational RNA Code for Amino Acids in Relation to Genetic Code in Evolution*

P. Schimmel, L. Ribas de Pouplana, 2001, The Journal of Biological Chemistry.

Genetic code in evolution: switching species‐specific aminoacylation with a peptide transplant

P. Schimmel, K. Wakasugi, C. L. Quinn, 1998, The EMBO journal.

Species-specific microhelix aminoacylation by a eukaryotic pathogen tRNA synthetase dependent on a single base pair.

P. Schimmel, C. L. Quinn, N. Tao, 1995, Biochemistry.

An operational RNA code for amino acids and possible relationship to genetic code.

R Giegé, P. Schimmel, S. Yokoyama, 1993, Proceedings of the National Academy of Sciences of the United States of America.

Aminoacyl tRNA Synthetases

P. Schimmel, 2002 .

Major Anticodon-binding Region Missing from an Archaebacterial tRNA Synthetase*

P. Schimmel, B. Steer, 1999, The Journal of Biological Chemistry.

Domain-domain communication in a miniature archaebacterial tRNA synthetase.

P. Schimmel, B. Steer, 1999, Proceedings of the National Academy of Sciences of the United States of America.

RNA-RNA interactions between oligonucleotide substrates for aminoacylation.

P. Schimmel, B. Henderson, 1997, Bioorganic & medicinal chemistry.

Species-specific tRNA recognition in relation to tRNA synthetase contact residues.

P. Schimmel, L. Ribas de Pouplana, S. Nair, 1997, Journal of molecular biology.

Functional expansion of human tRNA synthetases achieved by structural inventions

P. Schimmel, Xiang-Lei Yang, M. Guo, 2010, FEBS letters.

Retrovirus-Specific Packaging of Aminoacyl-tRNA Synthetases with Cognate Primer tRNAs

Sunghoon Kim, P. Schimmel, K. Musier-Forsyth, 2002, Journal of Virology.

Essential nontranslational functions of tRNA synthetases.

Paul Schimmel, P. Schimmel, Min Guo, 2013, Nature chemical biology.

Structural switch of lysyl-tRNA synthetase between translation and transcription.

Sunghoon Kim, P. Schimmel, H. Nechushtan, 2013, Molecular cell.

Novel transfer RNAs that are active in Escherichia coli.

P. Schimmel, Y. Hou, 1992, Biochemistry.

An aminoacyl tRNA synthetase binds to a specific DNA sequence and regulates its gene transcription

P. Schimmel, S. Putney, 1981, Nature.

Two Classes of tRNA Synthetases Suggested by Sterically Compatible Dockings on tRNA Acceptor Stem

P. Schimmel, L. R. Pouplana, 2001, Cell.

The universal YrdC/Sua5 family is required for the formation of threonylcarbamoyladenosine in tRNA

V. de Crécy-Lagard, P. Schimmel, J. Williamson, 2009, Nucleic acids research.

Transfer RNA: From minihelix to genetic code

P. Schimmel, L. R. Pouplana, 1995, Cell.

An Active Dominant Mutation of Glycyl-tRNA Synthetase Causes Neuropathy in a Charcot-Marie-Tooth 2D Mouse Model

R. Burgess, P. Schimmel, G. Cox, 2006, Neuron.

Homeostatic mechanisms by alternative forms of tRNA synthetases.

P. Schimmel, M. Guo, 2012, Trends in biochemical sciences.

New functions of aminoacyl-tRNA synthetases beyond translation

P. Schimmel, Xiang-Lei Yang, M. Guo, 2010, Nature Reviews Molecular Cell Biology.

Oligonucleotide-directed peptide synthesis in a ribosome- and ribozyme-free system.

P. Schimmel, K. Tamura, 2001, Proceedings of the National Academy of Sciences of the United States of America.

A universal plate format for increased throughput of assays that monitor multiple aminoacyl transfer RNA synthetase activities.

P. Schimmel, W. Waas, K. Beebe, 2007, Analytical biochemistry.

Five specific protein-transfer RNA interactions.

P. Schimmel, 1980, CRC critical reviews in biochemistry.

Hazards and their exploitation in the applications of molecular biology to structure-function relationships.

P. Schimmel, 1990, Biochemistry.

An E. coli aminoacyl-tRNA synthetase can substitute for yeast mitochondrial enzyme function in vivo

P. Schimmel, H. Edwards, 1987, Cell.

Deletion of an essential gene in Escherichia coli by site-specific recombination with linear DNA fragments

P. Schimmel, M. Jasin, 1984, Journal of bacteriology.

LEU3 of Saccharomyces cerevisiae activates multiple genes for branched-chain amino acid biosynthesis by binding to a common decanucleotide core sequence

P. Schimmel, P. Friden, P Schimmel, 1988, Molecular and cellular biology.

Evidence that two present-day components needed for the genetic code appeared after nucleated cells separated from eubacteria.

P. Schimmel, L. Ribas de Pouplana, M. Frugier, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Evidence that the 3' end of a tRNA binds to a site in the adenylate synthesis domain of an aminoacyl-tRNA synthetase.

P. Schimmel, K. Hill, Paul Schimmel, 1989, Biochemistry.

Relationship of two human tRNA synthetases used in cell signaling.

P. Schimmel, K. Ewalt, Xiang-lei Yang, 2004, Trends in biochemical sciences.

Mutational switching of a yeast tRNA synthetase into a mammalian-like synthetase cytokine.

P. Schimmel, K. Ewalt, Xiang-lei Yang, 2002, Biochemistry.

Structure‐specific tRNA‐binding protein from the extreme thermophile Aquifex aeolicus

P. Schimmel, M. Swairjo, A. J. Morales, 1999, The EMBO journal.

Origin of mitochondria in relation to evolutionary history of eukaryotic alanyl-tRNA synthetase.

P. Schimmel, L. Ribas de Pouplana, L. R. Pouplana, 2000, Proceedings of the National Academy of Sciences of the United States of America.

A view into the origin of life: aminoacyl-tRNA synthetases

P. Schimmel, L. R. Pouplana, L. R. de Pouplana, 2000, Cellular and Molecular Life Sciences CMLS.

C-terminal zinc-containing peptide required for RNA recognition by a class I tRNA synthetase.

P. Schimmel, J. Landro, E. Glasfeld, 1996, Biochemistry.

Identification of Four Genes Necessary for Biosynthesis of the Modified Nucleoside Queuosine*

D. Metzgar, J. Reader, V. de Crécy-Lagard, 2004, Journal of Biological Chemistry.

Primary structure of histidine-tRNA synthetase and characterization of hisS transcripts.

K. Biemann, P. Schimmel, B. Gibson, 1985, The Journal of biological chemistry.

In vitro transcription of the histidine operon. Identification of the his promoter and leader and readthrough transcripts.

P. Schimmel, R. Freedman, 1981, The Journal of biological chemistry.

An aminoacyl tRNA synthetase whose sequence fits into neither of the two known classes

A. Ortiz, P. Schimmel, B. Mukhopadhyay, 2001, Nature.

All You Need Is RNA

P. Schimmel, R. Alexander, 1998, Science.

Maintaining genetic code through adaptations of tRNA synthetases to taxonomic domains.

P. Schimmel, H. Motegi, K. Shiba, 1997, Trends in biochemical sciences.

RNA recognition by designed peptide fusion creates "artificial" tRNA synthetase

P. Schimmel, R. Giegé, M. Frugier, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Functional Redundancy in the Nonspecific RNA Binding Domain of a Class I tRNA Synthetase*

P. Schimmel, Chien-Chia Wang, A. J. Morales, 2000, The Journal of Biological Chemistry.

Subtle atomic group discrimination in the RNA minor groove.

P. Schimmel, M. Frugier, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Assembly of a class I tRNA synthetase from products of an artificially split gene.

P. Schimmel, J. Burbaum, 1991, Biochemistry.

Yeast LEU2. Repression of mRNA levels by leucine and primary structure of the gene product.

P. Schimmel, A. Andreadis, M. Hermodson, 1984, The Journal of biological chemistry.

Insertion of new sequences into the catalytic domain of an enzyme.

R. Starzyk, P. Schimmel, J. Burbaum, 1989, Biochemistry.

A prokaryote and human tRNA synthetase provide an essential RNA splicing function in yeast mitochondria.

S. Martinis, P. Schimmel, C. Wang, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Understanding structural relationships proteins of unsolved three‐dimensional structure

J J Burbaum, R. Starzyk, P. Schimmel, 1990, Proteins.

Non-covalent protein assembly

P. Schimmel, J. Landro, 1993 .

Switching recognition of two tRNA synthetases with an amino acid swap in a designed peptide.

P. Schimmel, D. S. Auld, Paul Schimmel, 1995, Science.

Amino acid binding by the Class I aminoacyl‐tRNA synthetases: Role for a conserved proline in the signature sequence

P. Schimmel, J. Burbaum, 1992, Protein science : a publication of the Protein Society.

Synthetic peptide model of an essential region of an aminoacyl-tRNA synthetase.

S. Park, P. Schimmel, W. Miller, 1990, Biochemistry.

Aminoacyl tRNA synthetases: general scheme of structure-function relationships in the polypeptides and recognition of transfer RNAs.

P. Schimmel, P Schimmel, 1987, Annual review of biochemistry.

Internal structural features of E. coli glycyl-tRNA synthetase examined by subunit polypeptide chain fusions.

P. Schimmel, M. Toth, 1986, The Journal of biological chemistry.

M411_3c 107..110

Paul Schimmel, Angel R. Ortiz, Biswarup Mukhopadhyay, 2001 .

Amino acid replacements that compensate for a large polypeptide deletion in an enzyme.

P. Schimmel, M. Jasin, C. Ho, 1985, Science.

Acinetobacter sp. ADP1: an ideal model organism for genetic analysis and genome engineering.

Philippe Marlière, Paul Schimmel, David Metzgar, 2004, Nucleic acids research.

Cloning, partial sequencing, and in vitro transcription of the gene for alanine tRNA synthetase.

P. Schimmel, S. Putney, D. Meléndez, 1981, The Journal of biological chemistry.

RNA and DNA sequence recognition and structure-function of aminoacyl tRNA synthetases

R. Starzyk, P. Schimmel, S. Putney, 1982 .

GENES FOR TWO E. COLI AMINOACYL tRNA SYNTHETASES

P. Schimmel, T. Keng, S. Putney, 1982 .

Dominant negative inhibition by fragments of a monomeric enzyme.

P. Schimmel, W. Miller, K. Shiba, 1996, Proceedings of the National Academy of Sciences of the United States of America.

GTP hydrolysis in protein synthesis: two for Tu?

P. Schimmel, 1993, Science.

Isolation, characterization and structural implications of a nuclease-digested complex of aminoacyl transfer RNA and Escherichia coli elongation factor Tu.

P. Schimmel, D. Miller, E. Jekowsky, 1977, Journal of molecular biology.

Purification and properties of alanine tRNA synthetase from Escherichia coli A tetramer of identical subunits.

R. Sauer, P. Schimmel, S. Putney, 1981, The Journal of biological chemistry.

Strong selective pressure to use G:U to mark an RNA acceptor stem for alanine.

K. Hayashibara, P. Schimmel, K. Shiba, 1998, Biochemistry.

Gain-of-function mutational activation of human tRNA synthetase procytokine.

M. Kapoor, P. Schimmel, K. Ewalt, 2007, Chemistry & biology.

Global effects of mistranslation from an editing defect in mammalian cells.

Paul Schimmel, P. Schimmel, L. Nangle, 2006, Chemistry & biology.

Positional recognition of a tRNA determinant dependent on a peptide insertion.

P. Schimmel, M. Swairjo, M. Lovato, 2004, Molecular cell.

Aminoacyl-tRNA Synthetases as Clues to Establishment of the Genetic Code

P. Schimmel, L. R. Pouplana, 2004 .

Aminoacyl-tRNA synthetases: potential markers of genetic code development.

P. Schimmel, L. Ribas de Pouplana, L. R. Pouplana, 2001, Trends in biochemical sciences.

Structure of transfer RNA-AMINOACYL TRANSFER RNA synthetase complexes investigated by nuclease digestion.

P. Schimmel, L. Dickson, 1975, Archives of biochemistry and biophysics.

An editing-defective aminoacyl-tRNA synthetase is mutagenic in aging bacteria via the SOS response

P. Schimmel, Jamie M. Bacher, 2007, Proceedings of the National Academy of Sciences.

Elucidation of tRNA‐dependent editing by a class II tRNA synthetase and significance for cell viability

Paul Schimmel, P. Schimmel, K. Beebe, 2003, The EMBO journal.

Synthesis and purification of oligoribonucleotides using T4 RNA ligase and reverse-phase chromatography.

W. Herlihy, H. Munro, P. Schimmel, 1985, Analytical biochemistry.

Acceptor stem and anticodon RNA hairpin helix interactions with glutamine tRNA synthetase.

S. Martinis, D. Söll, P. Schimmel, 1993, Biochimie.

Small RNA helices as substrates for aminoacylation and their relationship to charging of transfer RNAs.

C. Francklyn, P. Schimmel, K. Musier-Forsyth, 1992, European journal of biochemistry.

A nucleotide that enhances the charging of RNA minihelix sequence variants with alanine.

C. Francklyn, P. Schimmel, J. P. Shi, 1990, Biochemistry.

Human Tyr-tRNA synthetase is a potent PARP-1 activating effector target for resveratrol

P. Schimmel, M. Sajish, 2014, Nature.

A domain for editing by an archaebacterial tRNA synthetase.

P. Schimmel, L. Ribas de Pouplana, K. Beebe, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Interstice mutations that block site-to-site translocation of a misactivated amino acid bound to a class I tRNA synthetase

Anthony C. Bishop, P. Schimmel, A. Bishop, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Thiol ligation of two zinc atoms to a class I tRNA synthetase: evidence for unshared thiols and role in amino acid binding and utilization.

P. Schimmel, J. Penner‐Hahn, D. Tierney, 1994, Biochemistry.

Inhibition of tumor angiogenesis by a natural fragment of a tRNA synthetase.

Ellie Tzima, Paul Schimmel, P. Schimmel, 2006, Trends in biochemical sciences.

Equilibrium measurements of the binding of cytidine 3'-phosphate to ribonuclease.

P. Schimmel, G. Hammes, 1965, Journal of the American Chemical Society.

Trbp111 selectively binds a noncovalently assembled tRNA-like structure

P. Schimmel, T. Kushiro, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Alanine transfer RNA synthetase: structure-function relationships and molecular recognition of transfer RNA.

P. Schimmel, 1990, Advances in enzymology and related areas of molecular biology.

Construction of intra-domain chimeras of aminoacyl-tRNA synthetases.

R. Starzyk, P. Schimmel, 1989, Journal of biomolecular structure & dynamics.

Modular arrangement of functional domains along the sequence of an aminoacyl tRNA synthetase

L. Regan, P. Schimmel, M. Jasin, 1983, Nature.

A DNA fragment with an alpha-phosphorothioate nucleotide at one end is asymmetrically blocked from digestion by exonuclease III and can be replicated in vivo.

S. Benkovic, P. Schimmel, S J Benkovic, 1981, Proceedings of the National Academy of Sciences of the United States of America.

Protein synthesis editing by a DNA aptamer.

P. Schimmel, S. Hale, S P Hale, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Relaxation spectra of enzymatic reactions.

P. Schimmel, G. Hammes, 1967, The Journal of physical chemistry.

Tumor endothelial cell tube formation model for determining anti-angiogenic activity of a tRNA synthetase cytokine.

P. Schimmel, W. Kiosses, Quansheng Zhou, 2008, Methods.

LEU3ofSaccharomyces cerevisiae Activates Multiple Genesfor Branched-Chain AminoAcidBiosynthesis byBinding toa CommonDecanucleotide CoreSequence

P. Schimmel, 1988 .

P. Schimmel, 1979 .

Dispensable pieces of an aminoacyl tRNA synthetase which activate the catalytic site

L. Regan, P. Schimmel, M. Jasin, 1984, Cell.

Peptide synthesis with a template-like RNA guide and aminoacyl phosphate adaptors

P. Schimmel, K. Tamura, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Efficient 50S ribosome-catalyzed peptide bond synthesis with an aminoacyl minihelix.

N. Sardesai, R. Green, P. Schimmel, 1999, Biochemistry.

Drug target validation: lethal infection blocked by inducible peptide.

P. Schimmel, T. Li, P. Wendler, 2000, Proceedings of the National Academy of Sciences of the United States of America.

One of two genes encoding glycyl-tRNA synthetase in Saccharomyces cerevisiae provides mitochondrial and cytoplasmic functions.

P. Schimmel, R. Turner, M. Lovato, 2000, The Journal of biological chemistry.

Effect of transfer ribonucleic acid on the rate law and mechanism of the adenosine triphosphate--pyrophosphate isotope exchange reaction of an aminoacyl transfer ribonucleic acid synthetase.

P. Schimmel, M. McNeil, 1972, Archives of biochemistry and biophysics.

Transiently misacylated tRNA is a primer for editing of misactivated adenylates by class I aminoacyl-tRNA synthetases.

Paul Schimmel, P. Schimmel, B. Nordin, 2003, Biochemistry.

Mutational separation of two pathways for editing by a class I tRNA synthetase.

Paul Schimmel, Shigeyuki Yokoyama, Osamu Nureki, 2002, Molecular cell.

Discrete determinants in transfer RNA for editing and aminoacylation.

P. Schimmel, S. Hale, D. S. Auld, 1997, Science.

Human alanyl-tRNA synthetase: conservation in evolution of catalytic core and microhelix recognition.

T. Noda, P. Schimmel, K. Shiba, 1995, Biochemistry.

Effect of 2-3-diphosphoglycerate and ATP on ethyl isocyanide binding to human hemoglobin.

P. Schimmel, H. H. Lo, 1972, Biochimica et biophysica acta.

Construction and analysis of deletions in the amino-terminal extension of glutamine tRNA synthetase of Saccharomyces cerevisiae.

P. Schimmel, S. Ludmerer, 1987, The Journal of biological chemistry.

A bacterial and silkworm aminoacyl-tRNA synthetase have a common epitope which maps to the catalytic domain of each.

L. Regan, P. Schimmel, J. Dignam, 1986, The Journal of biological chemistry.

Primary structures of both subunits of Escherichia coli glycyl-tRNA synthetase.

K. Biemann, T. Webster, P. Schimmel, 1983, The Journal of biological chemistry.

Two conformations of a crystalline human tRNA synthetase–tRNA complex: implications for protein synthesis

P. Schimmel, K. Ewalt, D. McRee, 2006, The EMBO journal.

Optical rotatory dispersion of ribonuclease and ribonuclease--nucleotide complexes.

P. Schimmel, G. Hammes, R. Cathou, 1965, Biochemistry.

Two tissue-specific isozymes of creatine kinase have closely matched amino acid sequences.

K. Biemann, H. Munro, P. Schimmel, 1985, Proceedings of the National Academy of Sciences of the United States of America.

Inhibited cell growth and protein functional changes from an editing-defective tRNA synthetase.

V. de Crécy-Lagard, P. Schimmel, Jamie M. Bacher, 2005, Proceedings of the National Academy of Sciences of the United States of America.

A sulfhydryl presumed essential is not required for catalysis by an aminoacyl-tRNA synthetase.

P. Schimmel, A. Profy, 1986, The Journal of biological chemistry.

Simultaneous binding of two proteins to opposite sides of a single transfer RNA

P. Schimmel, R. Giegé, T. Nomanbhoy, 2001, Nature Structural Biology.

Possible role of aminoacyl-RNA complexes in noncoded peptide synthesis and origin of coded synthesis.

P. Schimmel, B. Henderson, Paul Schimmel, 1994, Proceedings of the National Academy of Sciences of the United States of America.

Activation of angiogenic signaling pathways by two human tRNA synthetases.

P. Schimmel, K. Ewalt, 2002, Biochemistry.

Functional compensation of a recognition-defective transfer RNA by a distal base pair substitution.

P. Schimmel, Y. Hou, 1992, Biochemistry.

Extracellular tyrosyl‐tRNA synthetase cleaved by plasma proteinases and stored in platelet α‐granules: Potential role in monocyte activation

P. Schimmel, C. Thornburg, T. Kanaji, 2020, Research and practice in thrombosis and haemostasis.

Approaches to understanding the mechanism of specific protein-transfer RNA interactions

P. Schimmel, 1977 .

Functional contacts of a transfer RNA synthetase with 2′-hydroxyl groups in the RNA minor groove

P. Schimmel, K. Musier-Forsyth, 1992, Nature.

A tipping point for mistranslation and disease

P. Schimmel, M. Guo, 2009, Nature Structural &Molecular Biology.

Two photo-cross-linked complexes of isoleucine specific transfer ribonucleic acid with aminoacyl transfer ribonucleic acid synthetases.

P. Schimmel, H. Schoemaker, G. Budzik, 1975, The Journal of biological chemistry.

Structure-specific tRNA Determinants for Editing a Mischarged Amino Acid*

P. Schimmel, K. Beebe, E. Merriman, 2003, Journal of Biological Chemistry.

RNA Determinants for Translational Editing

P. Schimmel, B. Nordin, 1999, The Journal of Biological Chemistry.

Domain-domain communication in aminoacyl-tRNA synthetases.

P. Schimmel, R. Alexander, Paul Schimmel, 2001, Progress in nucleic acid research and molecular biology.

Distinct domains of tRNA synthetase recognize the same base pair

Paul Schimmel, P. Schimmel, K. Beebe, 2008, Nature.

Idiographic representation of conserved domain of a class II tRNA synthetase of unknown structure

Matthew W. Davis, P. Schimmel, L. R. Pouplana, 1993, Protein science : a publication of the Protein Society.

Aminoacylation of RNA oligonucleotides: minimalist structures and origin of specificity

P. Schimmel, Karin Musier Forsyth, 1993, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Aminoacylation of RNA minihelices: implications for tRNA synthetase structural design and evolution.

P. Schimmel, D. Buechter, 1993, Critical reviews in biochemistry and molecular biology.

Classes of aminoacyl-tRNA synthetases and the establishment of the genetic code.

P. Schimmel, 1991, Trends in biochemical sciences.

The dissection and engineering of sites that affect the activity of an enzyme of unknown structure.

P. Schimmel, K. Hill, 1990, Biotechnology.

Interpretation of Experiments that Delineate Transfer RNA Recognition in Vivo and in Vitro

P. Schimmel, 1990 .

Mass spectra of partial protein hydrolysates as a multiple phase check for long polypeptides deduced from DNA sequences: NH2-terminal segment of alanine tRNA synthetase.

W. Herlihy, K. Biemann, P. Schimmel, 1980, Proceedings of the National Academy of Sciences of the United States of America.

Rescuing an essential enzyme–RNA complex with a non‐essential appended domain

P. Schimmel, E.Fayelle Whelihan, E.Fayelle Whelihan, 1997, The EMBO journal.

Minor groove recognition of the critical acceptor helix base pair by an appended module of a class II tRNA synthetase.

P. Schimmel, D. Buechter, 1995, Biochemistry.

Aminoacylation of alanine minihelices. "Discriminator" base modulates transition state of single turnover reaction.

P. Schimmel, J. P. Shi, 1991, The Journal of biological chemistry.

Mutant enzymes and dissected tRNAs that elucidate motifs for protein-RNA recognition

P. Schimmel, 1991 .

SYNTHET ASES: GENERAL FEATURES AND RECOGNITION OF TRANSFER RNAS

P. Schimmel, Dieter Soil, 1979 .

Recent results on how aminoacyl transfer RNA synthetases recognize specific transfer RNAs

P. Schimmel, 1979, Molecular and Cellular Biochemistry.

Isotope labeling of free and aminoacyl transfer RNA synthetase-bound transfer RNA.

P. Schimmel, H. Schoemaker, 1976, The Journal of biological chemistry.

Mapping the structure of specific protein-transfer RNA complexes by a tritium labeling method.

P. Schimmel, H. Schoemaker, 1979, Methods in enzymology.

Evidence that tRNA synthetase-directed proton transfer stops mistranslation.

P. Schimmel, W. Waas, 2007, Biochemistry.

Genetic Code Ambiguity Confers a Selective Advantage on Acinetobacter baylyi

D. Metzgar, V. de Crécy-Lagard, P. Schimmel, 2007, Journal of bacteriology.

Isoleucyl transfer ribonucleic acid synthetase. The role of magnesium in amino acid activation.

P. Schimmel, F. Cole, 1970, Biochemistry.

Specificity for aminoacylation of an RNA helix: an unpaired, exocyclic amino group in the minor groove.

R. Green, J. Doudna, S. Scaringe, 1991, Science.

Ancient tRNA synthetase meets modern structural biology.

P. Schimmel, M. Guo, 2009, Structure.

An operational RNA code for amino acids and variations in critical nucleotide sequences in evolution

P. Schimmel, 1995, Journal of Molecular Evolution.

RNA minihelices and the decoding of genetic information

P. Schimmel, 1991, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

An Escherichia coli tyrosine transfer RNA is a leucine-specific transfer RNA in the yeast Saccharomyces cerevisiae.

P. Schimmel, V. Trézéguet, H. Edwards, 1991, Proceedings of the National Academy of Sciences of the United States of America.

A human aminoacyl-tRNA syl of angiogenesis

P. Schimmel, K. Ewalt, D. Cheresh, 2016 .

DNA APTAMER TARGETS TRANSLATIONAL EDITING MOTIF IN A TRNA SYNTHETASE

P. Schimmel, S. Hale, 1997 .

Evidence for Annexin II-S100A10 Complex and Plasmin in Mobilization of Cytokine Activity of Human TrpRS*

M. Kapoor, P. Schimmel, C. A. Myers, 2008, Journal of Biological Chemistry.

A new gamma-interferon-inducible promoter and splice variants of an anti-angiogenic human tRNA synthetase.

P. Schimmel, K. Ewalt, Eveline H Shue, 2004, Nucleic acids research.

Atomic Determinants for Aminoacylation of RNA Minihelices and Relationship to Genetic Code

P. Schimmel, K. Musier-Forsyth, 1999 .

Microhelix aminoacylation by a class I tRNA synthetase. Non-conserved base pairs required for specificity.

S. Martinis, P. Schimmel, 1993, The Journal of biological chemistry.

Aminoacyl-tRNA synthetase-catalyzed cleavage of the glycosidic bond of 5-halogenated uridines.

P. Schimmel, S. W. Koontz, 1979, Journal of Biological Chemistry.

C-terminal peptide appendix in a class I tRNA synthetase needed for acceptor-helix contacts and microhelix aminoacylation.

P. Schimmel, S. Kim, J. Landro, 1993, Biochemistry.

Function independence of microhelix aminoacylation from anticodon binding in a class I tRNA synthetase.

P. Schimmel, S. Kim, 1992, The Journal of biological chemistry.

An RNA binding site in a tRNA synthetase with a reduced set of amino acids.

P. Schimmel, S. Kim, L. Ribas de Pouplana, 1994, Biochemistry.

Species Barrier to RNA Recognition Overcome with Nonspecific RNA Binding Domains*

P. Schimmel, Chien-Chia Wang, Paul Schimmel, 1999, The Journal of Biological Chemistry.

Exiting an RNA world

P. Schimmel, S. Kelley, 2000, Nature Structural Biology.

Transfer RNA conformation in solution investigated by isotope labeling.

P. Schimmel, R. Gamble, 1974, Proceedings of the National Academy of Sciences of the United States of America.

Genetic code origins: experiments confirm phylogenetic predictions and may explain a puzzle.

P. Schimmel, L. R. Pouplana, 1999, Proceedings of the National Academy of Sciences of the United States of America.

Blocking site-to-site translocation of a misactivated amino acid by mutation of a class I tRNA synthetase

P. Schimmel, A. Bishop, T. Nomanbhoy, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Errors from selective disruption of the editing center in a tRNA synthetase.

P. Schimmel, T. Nomanbhoy, T. Hendrickson, 2000, Biochemistry.

Aminoacylation error correction

P. Schimmel, S. Hale, Laura Lin, 1996, Nature.

A mutation in the small (alpha) subunit of glycyl-tRNA synthetase affects amino acid activation and subunit association parameters.

P. Schimmel, M. Toth, 1990, The Journal of biological chemistry.

Misactivated amino acids translocate at similar rates across surface of a tRNA synthetase.

P. Schimmel, T. Nomanbhoy, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Acceptor helix interactions in a class II tRNA synthetase: photoaffinity cross-linking of an RNA miniduplex substrate.

P. Schimmel, K. Musier-Forsyth, 1994, Biochemistry.

Purification of glutamine tRNA synthetase from Saccharomyces cerevisiae. A monomeric aminoacyl-tRNA synthetase with a large and dispensable NH2-terminal domain.

P. Schimmel, D. Wright, S. Ludmerer, 1993, The Journal of biological chemistry.

Chemical Relaxation Spectra: Calculation of Relaxation Times for Complex Mechanisms1

P. Schimmel, G. Hammes, 1966 .

Relaxation spectra of the iron spin transition in methemoglobin.

P. Schimmel, A. Schwartz, 1974, Journal of molecular biology.

Analysis of the skeletal configuration of crystalline hen egg-white lysozyme.

P. Schimmel, D. Brant, 1967, Proceedings of the National Academy of Sciences of the United States of America.

Direct and specific photochemical cross-linking of adenosine 5'-triphosphate to an aminoacyl-tRNA synthetase.

P. Schimmel, V. Yue, 1977, Biochemistry.

Mutant aminoacyl-tRNA synthetase that compensates for a mutation in the major identity determinant of its tRNA.

P. Schimmel, W. Miller, Ya-Ming Hou, 1991, Biochemistry.

DNA Aptamer Targets Translational Editing Motif in a tRNA Synthetase.

P. Schimmel, S. Hale, 1997 .

RNA binding determinant in some class I tRNA synthetases identified by alignment-guided mutagenesis.

P. Schimmel, K. Shiba, A. Shepard, 1992, Proceedings of the National Academy of Sciences of the United States of America.

Different adaptations of the same peptide motif for tRNA functional contacts by closely homologous tRNA synthetases.

P. Schimmel, B. Steer, 1999, Biochemistry.

Overlapping nucleotide determinants for specific aminoacylation of RNA microhelices.

C. Francklyn, P. Schimmel, Jian‐Ping Shi, 1992, Science.

Enzymatic aminoacylation of single-stranded RNA with an RNA cofactor.

S. Scaringe, P. Schimmel, K. Musier-Forsyth, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Gene for Escherichia coli glycyl-tRNA synthetase has tandem subunit coding regions in the same reading frame.

R. Sauer, T. Webster, P. Schimmel, 1982, The Journal of biological chemistry.