R. Conaway

发表

Quantitative proteomic analysis of distinct mammalian Mediator complexes using normalized spectral abundance factors

M. Washburn, L. Florens, Andrew C. Paoletti, 2006, Proceedings of the National Academy of Sciences.

Emerging Roles of Ubiquitin in Transcription Regulation

R. Conaway, J. Conaway, C. S. Brower, 2002, Science.

Structure of the Cul1–Rbx1–Skp1–F boxSkp2 SCF ubiquitin ligase complex

S. Elledge, M. Pagano, R. Conaway, 2002, Nature.

Mechanism of transcription initiation and promoter escape by RNA polymerase II.

R. Conaway, J. Conaway, A. Dvir, 2001, Current opinion in genetics & development.

RNA polymerase II transcription factor SIII. II. Functional properties and role in RNA chain elongation.

R. Conaway, J. Conaway, J. Bradsher, 1993, The Journal of biological chemistry.

Positive regulation of general transcription factor SIII by a tailed ubiquitin homolog.

William Arbuthnot Sir Lane, R. Conaway, J. Conaway, 1995, Proceedings of the National Academy of Sciences of the United States of America.

Transcription elongation and human disease.

R. Conaway, J. Conaway, J W Conaway, 1999, Annual review of biochemistry.

Conserved abundance and topological features in chromatin‐remodeling protein interaction networks

Mihaela E. Sardiu, D. Herman, M. Washburn, 2015, EMBO reports.

Probabilistic assembly of human protein interaction networks from label-free quantitative proteomics

Mihaela E. Sardiu, M. Washburn, L. Florens, 2008, Proceedings of the National Academy of Sciences.

RNA Polymerase II Transcription

Danny Reinberg, D. Reinberg, R. Conaway, 2004 .

The Human EKC/KEOPS Complex Is Recruited to Cullin2 Ubiquitin Ligases by the Human Tumour Antigen PRAME

H. Stunnenberg, R. Conaway, J. Conaway, 2012, PloS one.

Subunit Architecture and Functional Modular Rearrangements of the Transcriptional Mediator Complex

C. Tomomori-Sato, Shigeo Sato, R. Conaway, 2014, Cell.

Identification of New Subunits of the Multiprotein Mammalian TRRAP/TIP60-containing Histone Acetyltransferase Complex*

T. Parmely, C. Tomomori-Sato, Shigeo Sato, 2003, Journal of Biological Chemistry.

YY1 functions with INO80 to activate transcription

M. Washburn, L. Florens, R. Conaway, 2007, Nature Structural &Molecular Biology.

Multiple modes of regulation of the human Ino80 SNF2 ATPase by subunits of the INO80 chromatin-remodeling complex

R. Conaway, J. Conaway, Lu Chen, 2013, Proceedings of the National Academy of Sciences.

New clues to actin function in chromatin regulation

R. Conaway, J. Conaway, A. J. Gottschalk, 2008, Nature Structural &Molecular Biology.

Mechanism of assembly of the RNA polymerase II preinitiation complex. Evidence for a functional interaction between the carboxyl-terminal domain of the largest subunit of RNA polymerase II and a high molecular mass form of the TATA factor.

R. Conaway, J. Conaway, J. Bradsher, 1992, The Journal of biological chemistry.

Purification and assay of the human INO80 and SRCAP chromatin remodeling complexes.

R. Conaway, J. Conaway, T. Yao, 2006, Methods.

Transcription initiated by RNA polymerase II and purified transcription factors from liver. Transcription factors alpha, beta gamma, and delta promote formation of intermediates in assembly of the functional preinitiation complex.

R. Conaway, J. Conaway, 1990, The Journal of biological chemistry.

Mechanism of promoter selection by RNA polymerase II: mammalian transcription factors alpha and beta gamma promote entry of polymerase into the preinitiation complex.

R. Conaway, J. Conaway, K. Garrett, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Transcription factor SIII: a novel component of the RNA polymerase II elongation complex.

R. Conaway, J. Conaway, J. Bradsher, 1993, Cellular & molecular biology research.

A Mammalian Homolog of Drosophila melanogaster Transcriptional Coactivator Intersex Is a Subunit of the Mammalian Mediator Complex*

T. Parmely, C. Tomomori-Sato, Shigeo Sato, 2003, Journal of Biological Chemistry.

A human cDNA encoding the small subunit of RNA polymerase II transcription factor SIII.

R. Conaway, J. Conaway, K. Garrett, 1994, Gene.

Identification of Elongin C and Skp1 Sequences That Determine Cullin Selection*

A. Mushegian, M. Ivan, R. Conaway, 2004, Journal of Biological Chemistry.

Degradation of p53 by adenovirus E4orf6 and E1B55K proteins occurs via a novel mechanism involving a Cullin-containing complex.

W. Kaelin, R. Conaway, J. Conaway, 2001, Genes & development.

Mechanism and regulation of transcriptional elongation by RNA polymerase II.

R. Conaway, J. Conaway, D. Reines, 1999, Current opinion in cell biology.

UBAP2/UBAP2L regulate UV-induced ubiquitylation of RNA polymerase II and are the human orthologues of yeast Def1.

R. Conaway, J. Conaway, J. Svejstrup, 2022, DNA repair.

Cockayne syndrome B protein regulates recruitment of the Elongin A ubiquitin ligase to sites of DNA damage

Brian D. Slaughter, R. Conaway, J. Conaway, 2017, The Journal of Biological Chemistry.

The Rbx1 subunit of SCF and VHL E3 ubiquitin ligase activates Rub1 modification of cullins Cdc53 and Cul2.

R. Conaway, J. Conaway, T. Kamura, 1999, Genes & development.

Biochemical purification and pharmacological inhibition of a mammalian prolyl hydroxylase acting on hypoxia-inducible factor

Mircea Ivan, Joan W Conaway, Irina Sorokina, 2002, Proceedings of the National Academy of Sciences of the United States of America.

The 3′ Pol II pausing at replication-dependent histone genes is regulated by Mediator through Cajal bodies’ association with histone locus bodies

C. Tomomori-Sato, Shigeo Sato, R. Conaway, 2022, Nature Communications.

Characterization of the Residues Phosphorylated in Vitro by Different C-terminal Domain Kinases*

M. Morange, R. Conaway, J. Conaway, 1998, The Journal of Biological Chemistry.

Role for the MED21-MED7 Hinge in Assembly of the Mediator-RNA Polymerase II Holoenzyme*

Mihaela E. Sardiu, M. Washburn, L. Florens, 2016, The Journal of Biological Chemistry.

Regulation of MYC Expression and Differential JQ1 Sensitivity in Cancer Cells

James E. Bradner, Cheng-Ming Chiang, Ananda L. Roy, 2014, PloS one.

Correction: Regulation of MYC Expression and Differential JQ1 Sensitivity in Cancer Cells

A. Shilatifard, J. Bradner, R. Conaway, 2015, PLoS ONE.

RNA polymerase II initiation factor α from rat liver is almost identical to human TFIIB

R. Conaway, J. Conaway, K. Garrett, 1992 .

Mechanism of assembly of the RNA polymerase II preinitiation complex. Transcription factors delta and epsilon promote stable binding of the transcription apparatus to the initiator element.

R. Conaway, J. Conaway, J. Bradsher, 1992, The Journal of biological chemistry.

Multifunctional RNA Polymerase I1 Initiation Factor 6 from Rat Liver

R. Conaway, Conaway, Hiroaki SerizawaS, 1993 .

A role for TFIIH in controlling the activity of early RNA polymerase II elongation complexes.

R. Conaway, J. Conaway, A. Dvir, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Assays for investigating transcription by RNA polymerase II in vitro.

R. Conaway, J. Conaway, A. Dvir, 1997, Methods.

Promoter Escape by RNA Polymerase II A ROLE FOR AN ATP COFACTOR IN SUPPRESSION OF ARREST BY POLYMERASE AT PROMOTER-PROXIMAL SITES*

R. Conaway, A. Dvir, Joan Weliky Conaway, 1996, The Journal of Biological Chemistry.

An RNA polymerase II transcription factor has an associated DNA-dependent ATPase (dATPase) activity strongly stimulated by the TATA region of promoters.

R. Conaway, J. Conaway, 1989, Proceedings of the National Academy of Sciences of the United States of America.

The RNA polymerase II general elongation factors.

R. Conaway, J. Conaway, D. Reines, 1996, Trends in biochemical sciences.

TFIIH action in transcription initiation and promoter escape requires distinct regions of downstream promoter DNA

R. Conaway, J. Conaway, A. Dvir, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Mechanism of promoter escape by RNA polymerase II.

R. Conaway, J. Conaway, A. Dvir, 1998, Cold Spring Harbor symposia on quantitative biology.

ATP activates transcription initiation from promoters by RNA polymerase II in a reversible step prior to RNA synthesis.

R. Conaway, J. Conaway, 1988, The Journal of biological chemistry.

A carboxyl-terminal-domain kinase associated with RNA polymerase II transcription factor delta from rat liver.

R. Conaway, J. Conaway, H. Serizawa, 1992, Proceedings of the National Academy of Sciences of the United States of America.

Direct Inhibition of RNA Polymerase II Transcription by RECQL5*

R. Conaway, J. Conaway, J. Svejstrup, 2009, The Journal of Biological Chemistry.

Edinburgh Research Explorer Regulation of the RNAPII Pool Is Integral to the DNA Damage Response

D. Tollervey, A. Stewart, R. Conaway, 2020 .

TFIIS and GreB Two Like-Minded Transcription Elongation Factors with Sticky Fingers

R. Conaway, J. Conaway, S. Kong, 2003, Cell.

Preparation and assay of RNA polymerase II elongation factors elongin and ELL.

A. Shilatifard, R. Conaway, J. Conaway, 2003, Methods in enzymology.

Light at the End of the Channel

R. Conaway, J. Conaway, 2000, Science.

The RNA polymerase II general elongation factors.

R. Conaway, J. Conaway, D. Reines, 1996, Trends in biochemical sciences.

Transcription Factors TFIIF, ELL, and Elongin Negatively Regulate SII-induced Nascent Transcript Cleavage by Non-arrested RNA Polymerase II Elongation Intermediates*

A. Shilatifard, R. Conaway, J. Conaway, 2001, The Journal of Biological Chemistry.

A Novel Activity Associated with RNA Polymerase II Elongation Factor SIII

R. Conaway, J. Conaway, Y. Takagi, 1995, The Journal of Biological Chemistry.

A multisubunit transcription factor essential for accurate initiation by RNA polymerase II.

R. Conaway, J. Conaway, 1989, The Journal of biological chemistry.

ELL-associated factors 1 and 2 are positive regulators of RNA polymerase II elongation factor ELL.

A. Shilatifard, R. Conaway, J. Conaway, 2005, Proceedings of the National Academy of Sciences of the United States of America.

A role for the Cockayne Syndrome B (CSB)-Elongin ubiquitin ligase complex in signal-dependent RNA polymerase II transcription

Brian D. Slaughter, R. Conaway, J. Conaway, 2021, The Journal of biological chemistry.

Transcription initiated by RNA polymerase II and purified transcription factors from liver. Cooperative action of transcription factors tau and epsilon in initial complex formation.

R. Conaway, J. Conaway, D. Reines, 1990, The Journal of biological chemistry.

Origins and activity of the Mediator complex.

R. Conaway, J. Conaway, Ronald C. Conaway, 2011, Seminars in cell & developmental biology.

ELL2, a new member of an ELL family of RNA polymerase II elongation factors.

A. Shilatifard, D. Duan, R. Conaway, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Title : Overcoming platinum resistance in preclinical models of ovarian cancer using the neddylation inhibitor MLN 4924

Berger, A. Jazaeri, Anindya Dutta, 2013 .

O-GlcNAc Transferase Catalyzes Site-Specific Proteolysis of HCF-1

W. Herr, R. Conaway, J. Conaway, 2011, Cell.

O-Linked N-acetylglucosamine transferase 1 regulates global histone H4 acetylation via stabilization of the nonspecific lethal protein NSL3

R. Conaway, J. Conaway, Yong Cai, 2017, The Journal of Biological Chemistry.

Association of DNA primase with the beta/gamma subunits of DNA polymerase alpha from Drosophila melanogaster embryos.

I. Lehman, R. Conaway, J. Rossignol, 1983, The Journal of biological chemistry.

Isolation of an intact DNA polymerase-primase from embryos of Drosophila melanogaster.

R. Conaway, J. Rossignol, I. R. Lehman, 1983, Proceedings of the National Academy of Sciences of the United States of America.

Synthesis by the DNA primase of Drosophila melanogaster of a primer with a unique chain length.

R. Conaway, I. R. Lehman, 1982, Proceedings of the National Academy of Sciences of the United States of America.

Activation of the SNF2 Family ATPase ALC1 by Poly(ADP-ribose) in a Stable ALC1·PARP1·Nucleosome Intermediate*

R. Conaway, J. Conaway, Aaron J. Gottschalk, 2012, The Journal of Biological Chemistry.

Metabolic Regulation of Transcription and Chromatin.

R. Conaway, 2018, Annual review of biochemistry.

Ribonucleic acid release activity of transcription termination protein rho is dependent on the hydrolysis of nucleoside triphosphates.

R. Conaway, J. Richardson, 1980, Biochemistry.

Biochemical assays for analyzing activities of ATP-dependent chromatin remodeling enzymes.

R. Conaway, J. Conaway, Lu Chen, 2014, Journal of visualized experiments : JoVE.

Generation and purification of human INO80 chromatin remodeling complexes and subcomplexes.

R. Conaway, J. Conaway, Lu Chen, 2014, Journal of visualized experiments : JoVE.

Human Mediator Subunit MED26 Functions as a Docking Site for Transcription Elongation Factors

A. Shilatifard, M. Washburn, L. Florens, 2011, Cell.

Roles of Mediator subunit MED26 in Regulation of Post‐initiation Events in RNA Pol II Transcription

Shigeo Sato, R. Conaway, J. Conaway, 2020, The FASEB Journal.

Immunoaffinity purification of protein complexes from Mammalian cells.

C. Tomomori-Sato, Shigeo Sato, R. Conaway, 2013, Methods in molecular biology.

Cell Reports Report Transcriptional Elongation Factor Elongin A Regulates Retinoic Acid-Induced Gene Expression during Neuronal Differentiation

R. Conaway, J. Conaway, T. Aso, 2012 .

Regulation of Heat Shock Gene Expression by RNA Polymerase II Elongation Factor, Elongin A*

A. Shilatifard, R. Conaway, J. Conaway, 2005, Journal of Biological Chemistry.

CTD-dependent and -independent mechanisms govern co-transcriptional capping of Pol II transcripts

C. Tomomori-Sato, Shigeo Sato, R. Conaway, 2018, Nature Communications.

CTD-dependent and -independent mechanisms govern co-transcriptional capping of Pol II transcripts

C. Tomomori-Sato, Shigeo Sato, R. Conaway, 2018, Nature Communications.

The RNA polymerase II elongation complex

R. Conaway, Teuiro Aso, Joan Weuky Conaway, 1995, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

RNA Polymerase II Transcription

D. Reinberg, R. Conaway, N. Proudfoot, 2004 .

Cryptic DNA-binding domain in the C terminus of RNA polymerase II general transcription factor RAP30.

R. Conaway, J. Conaway, S. Tan, 1994, Proceedings of the National Academy of Sciences of the United States of America.

Multifunctional RNA polymerase II initiation factor delta from rat liver. Relationship between carboxyl-terminal domain kinase, ATPase, and DNA helicase activities.

R. Conaway, J. Conaway, H. Serizawa, 1993, The Journal of biological chemistry.

A DNA primase activity associated with DNA polymerase alpha from Drosophila melanogaster embryos.

R. Conaway, I. R. Lehman, 1982, Proceedings of the National Academy of Sciences of the United States of America.

RNA polymerase II: a "nobel" enzyme demystified.

R. Conaway, J. Conaway, J. Svejstrup, 2006, Molecular cell.

RNA polymerase II bypass of oxidative DNA damage is regulated by transcription elongation factors

R. Conaway, J. Conaway, J. Egly, 2006, The EMBO journal.

The RNA polymerase II elongation complex.

A. Shilatifard, R. Conaway, J. Conaway, 2003, Annual review of biochemistry.

An RNA polymerase II transcription factor shares functional properties with Escherichia coli sigma 70.

R. Conaway, J. Conaway, 1990, Science.

Regulation of the RNAPII Pool Is Integral to the DNA Damage Response

D. Tollervey, A. Stewart, R. Conaway, 2020, Cell.

RNA Polymerase II and Basal Transcription Factors in Eukaryotes

R. Conaway, J. Conaway, 2004 .

von Hippel–Lindau protein binds hyperphosphorylated large subunit of RNA polymerase II through a proline hydroxylation motif and targets it for ubiquitination

R. Conaway, J. Conaway, Y. Sánchez, 2003, Proceedings of the National Academy of Sciences of the United States of America.

General transcription factors for RNA polymerase II.

R. Conaway, J. Conaway, J W Conaway, 1997, Progress in nucleic acid research and molecular biology.

Assembly of the Elongin A Ubiquitin Ligase Is Regulated by Genotoxic and Other Stresses*

Brian D. Slaughter, M. Washburn, L. Florens, 2015, The Journal of Biological Chemistry.

Dual Roles for Transcription Factor IIF in Promoter Escape by RNA Polymerase II*

R. Conaway, J. Conaway, R. Moreland, 1999, The Journal of Biological Chemistry.

A bacteriophage vector suitable for site-directed mutagenesis and high-level expression of multisubunit proteins in E. coli.

R. Conaway, J. Conaway, S. Tan, 1994, BioTechniques.

TRIM29 regulates the assembly of DNA repair proteins into damaged chromatin

M. Washburn, L. Florens, C. Tomomori-Sato, 2015, Nature Communications.

Mechanism of Action of RNA Polymerase II Elongation Factor Elongin

R. Conaway, J. Conaway, J. Hanas, 1998, The Journal of Biological Chemistry.

Purification of a human SRCAP complex that remodels chromatin by incorporating the histone variant H2A.Z into nucleosomes.

M. Washburn, L. Florens, R. Conaway, 2006, Biochemistry.

MED19 and MED26 Are Synergistic Functional Targets of the RE1 Silencing Transcription Factor in Epigenetic Silencing of Neuronal Gene Expression*

C. Tomomori-Sato, Shigeo Sato, R. Conaway, 2009, Journal of Biological Chemistry.

The INO80 chromatin remodeling complex in transcription, replication and repair.

R. Conaway, J. Conaway, 2009, Trends in biochemical sciences.

Transcription syndromes and the role of RNA polymerase II general transcription factors in human disease.

A. Shilatifard, R. Conaway, J. Conaway, 1996, The Journal of clinical investigation.

DNA-dependent protein kinase catalytic subunit (DNA-PKcs) contributes to incorporation of histone variant H2A.Z into nucleosomes

R. Conaway, J. Conaway, Yong Cai, 2019, Protein & Cell.

A conserved Mediator–CDK8 kinase module association regulates Mediator–RNA polymerase II interaction

C. Tomomori-Sato, Shigeo Sato, R. Conaway, 2013, Nature Structural &Molecular Biology.

The role of Mediator and Little Elongation Complex in transcription termination

M. Washburn, L. Florens, C. Tomomori-Sato, 2020, Nature Communications.

The Mediator complex and transcription elongation.

R. Conaway, J. Conaway, 2013, Biochimica et biophysica acta.

Roles of the Histone Chaperone FACT in Drosophila Gene Regulation and Chromatin Architecture

M. Blanchette, R. Conaway, J. Conaway, 2016, The FASEB Journal.

AFF4, a component of the ELL/P-TEFb elongation complex and a shared subunit of MLL chimeras, can link transcription elongation to leukemia.

A. Shilatifard, M. Washburn, L. Florens, 2010, Molecular cell.

Elongin functions as a loading factor for Mediator at ATF6α-regulated ER stress response genes

C. Tomomori-Sato, Shigeo Sato, R. Conaway, 2021, Proceedings of the National Academy of Sciences.

NRBP1-Containing CRL2/CRL4A Regulates Amyloid β Production by Targeting BRI2 and BRI3 for Degradation.

M. Washburn, L. Florens, C. Tomomori-Sato, 2020, Cell reports.

Defective Interplay of Activators and Repressors with TFIIH in Xeroderma Pigmentosum

D. Reinberg, X. Wang, C. Harris, 2001, Cell.

A Role for the TFIIH XPB DNA Helicase in Promoter Escape by RNA Polymerase II*

R. Conaway, J. Conaway, F. Tirode, 1999, The Journal of Biological Chemistry.

General initiation factors for RNA polymerase II.

R. Conaway, J. Conaway, J W Conaway, 1993, Annual review of biochemistry.

Imaging-based assays for investigating functions of the RNA polymerase II elongation factor Elongin and the Elongin ubiquitin ligase.

Brian D. Slaughter, R. Conaway, J. Conaway, 2019, Methods.

VHL-box and SOCS-box domains determine binding specificity for Cul2-Rbx1 and Cul5-Rbx2 modules of ubiquitin ligases.

Keiichi I Nakayama, Daisuke Kohda, R. Conaway, 2004, Genes & development.

MUF1, A Novel Elongin BC-interacting Leucine-rich Repeat Protein That Can Assemble with Cul5 and Rbx1 to Reconstitute a Ubiquitin Ligase*

A. Shilatifard, William Arbuthnot Sir Lane, R. Conaway, 2001, The Journal of Biological Chemistry.

The Elongin BC complex interacts with the conserved SOCS-box motif present in members of the SOCS, ras, WD-40 repeat, and ankyrin repeat families.

W. Kaelin, R. Conaway, J. Conaway, 1998, Genes & development.

Function and regulation of the Mediator complex.

R. Conaway, J. Conaway, Ronald C Conaway, 2011, Current opinion in genetics & development.

The mammalian Mediator complex and its role in transcriptional regulation.

Joan W Conaway, Tingting Yao, C. Tomomori-Sato, 2005, Trends in biochemical sciences.

Mediator structure and rearrangements required for holoenzyme formation

M. Washburn, L. Florens, R. Conaway, 2017, Nature.

Identification of the von Hippel-lindau tumor-suppressor protein as part of an active E3 ubiquitin ligase complex.

R. Klausner, R. Conaway, J. Conaway, 1999, Proceedings of the National Academy of Sciences of the United States of America.

A unified nomenclature for protein subunits of mediator complexes linking transcriptional regulators to RNA polymerase II.

Kevin Struhl, Min Han, Michael Carey, 2004, Molecular cell.

Subunit Organization of the Human INO80 Chromatin Remodeling Complex

Yong Cai, Laurence Florens, Michael P. Washburn, 2011, The Journal of Biological Chemistry.

Activation of HIF1alpha ubiquitination by a reconstituted von Hippel-Lindau (VHL) tumor suppressor complex.

R. Conaway, J. Conaway, T. Kamura, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Regulation of Hypoxia-Inducible mRNAs by the von Hippel-Lindau Tumor Suppressor Protein Requires Binding to Complexes Containing Elongins B/C and Cul2

W. Kaelin, R. Conaway, J. Conaway, 1998, Molecular and Cellular Biology.

Hepatitis B virus transactivator protein, HBx, associates with the components of TFIIH and stimulates the DNA helicase activity of TFIIH.

A. Siddiqui, R. Conaway, J. Conaway, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Transcription : mechanisms and regulation

R. Conaway, J. Conaway, Joan Weliky Conaway, 1994 .

Identification of a transcription factor IIIA-interacting protein.

B. Roe, R. Conaway, J. Conaway, 2000, Nucleic acids research.

Rbx1, a component of the VHL tumor suppressor complex and SCF ubiquitin ligase.

S. Elledge, W. Kaelin, William Arbuthnot Sir Lane, 1999, Science.

Mammalian mediator of transcriptional regulation and its possible role as an end-point of signal transduction pathways.

R. Kornberg, R. Conaway, J. Conaway, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Multiple Splice Variants of the Human HIF-3α Locus Are Targets of the von Hippel-Lindau E3 Ubiquitin Ligase Complex*

R. Conaway, J. Conaway, M. Ohh, 2003, The Journal of Biological Chemistry.

Interaction of von Hippel-Lindau tumor suppressor gene product with elongin.

R. Klausner, W. Linehan, R. Conaway, 1996, Methods in enzymology.

Elongin (SIII): a multisubunit regulator of elongation by RNA polymerase II

William Arbuthnot Sir Lane, R. Conaway, J. Conaway, 1995, Science.

MED26 regulates the transcription of snRNA genes through the recruitment of little elongation complex

C. Tomomori-Sato, Shigeo Sato, R. Conaway, 2015, Nature Communications.

Proteomics Reveals a Physical and Functional Link between Hepatocyte Nuclear Factor 4α and Transcription Factor IID*

M. Washburn, L. Florens, R. Conaway, 2009, The Journal of Biological Chemistry.

A set of consensus mammalian mediator subunits identified by multidimensional protein identification technology.

Boris Zybailov, Yong Cai, Michael P Washburn, 2004, Molecular cell.

Identification of Mammalian Mediator Subunits with Similarities to Yeast Mediator Subunits Srb5, Srb6, Med11, and Rox3* 210

William Arbuthnot Sir Lane, T. Parmely, C. Tomomori-Sato, 2003, The Journal of Biological Chemistry.

Mammalian mediator subunit mMED8 is an Elongin BC-interacting protein that can assemble with Cul2 and Rbx1 to reconstitute a ubiquitin ligase

Sohail Malik, Richard D Klausner, Robert Stearman, 2002, Proceedings of the National Academy of Sciences of the United States of America.

von Hippel-Lindau Protein Induces Hypoxia-regulated Arrest of Tyrosine Hydroxylase Transcript Elongation in Pheochromocytoma Cells*

R. Conaway, J. Conaway, M. Barton, 1999, The Journal of Biological Chemistry.

The tumour antigen PRAME is a subunit of a Cul2 ubiquitin ligase and associates with active NFY promoters

H. Stunnenberg, M. Washburn, L. Florens, 2011, The EMBO journal.

Synthetic peptides define critical contacts between elongin C, elongin B, and the von Hippel-Lindau protein.

B. Zbar, W. Kaelin, R. Conaway, 1999, The Journal of clinical investigation.

Control of elongation by RNA polymerase II.

A. Shilatifard, R. Conaway, J. Conaway, 2000, Trends in biochemical sciences.

Mechanism and regulation of transcriptional elongation and termination by RNA polymerase II.

A. Shilatifard, R. Conaway, J. Conaway, 1997, Current opinion in genetics & development.

A Role for FACT in RNA Polymerase II Promoter-Proximal Pausing.

J. Zeitlinger, M. Blanchette, R. Conaway, 2019, Cell reports.

Neuralized-like 1 (Neurl1) Targeted to the Plasma Membrane by N-Myristoylation Regulates the Notch Ligand Jagged1*

M. Washburn, L. Florens, C. Tomomori-Sato, 2008, Journal of Biological Chemistry.

Association of Cdk-activating kinase subunits with transcription factor TFIIH

R. Young, R. Weinberg, R. Conaway, 1995, Nature.

Mammalian Elongin A complex mediates DNA‐damage‐induced ubiquitylation and degradation of Rpb1

R. Conaway, J. Conaway, T. Aso, 2008, The EMBO journal.

In and out: histone variant exchange in chromatin.

J. Workman, R. Conaway, J. Conaway, 2005, Trends in biochemical sciences.

Cloning and Characterization of ELL-associated Proteins EAP45 and EAP20 A ROLE FOR YEAST EAP-LIKE PROTEINS IN REGULATION OF GENE EXPRESSION BY GLUCOSE*

A. Shilatifard, R. Conaway, J. Conaway, 2001 .

The Mammalian YL1 Protein Is a Shared Subunit of the TRRAP/TIP60 Histone Acetyltransferase and SRCAP Complexes*

J. Workman, M. Washburn, L. Florens, 2005, Journal of Biological Chemistry.

Subunit Architecture and Functional Modular Rearrangements of the Transcriptional Mediator Complex

C. Tomomori-Sato, Shigeo Sato, R. Conaway, 2014, Cell.

A Role for ATP and TFIIH in Activation of the RNA Polymerase II Preinitiation Complex Prior to Transcription Initiation (*)

R. Conaway, J. Conaway, A. Dvir, 1996, The Journal of Biological Chemistry.

The hunt for RNA polymerase II elongation factors: a historical perspective

R. Conaway, J. Conaway, 2019, Nature Structural & Molecular Biology.

An RNA Polymerase II Elongation Factor Encoded by the Human ELL Gene

A. Shilatifard, William Arbuthnot Sir Lane, R. Conaway, 1996, Science.

In Vivo Requirement of the RNA Polymerase II Elongation Factor Elongin A for Proper Gene Expression and Development

A. Shilatifard, R. Conaway, J. Conaway, 2004, Molecular and Cellular Biology.

Dissection of transcription factor TFIIF functional domains required for initiation and elongation.

R. Conaway, J. Conaway, S. Tan, 1995, Proceedings of the National Academy of Sciences of the United States of America.

Schizosaccharomyces pombe Pol II transcription elongation factor ELL functions as part of a rudimentary super elongation complex

M. Washburn, L. Florens, R. Conaway, 2018, Nucleic acids research.

Phosphorylation of C-terminal domain of RNA polymerase II is not required in basal transcription

R. Conaway, J. Conaway, H. Serizawa, 1993, Nature.

Endoplasmic Reticulum Stress-responsive Transcription Factor ATF6α Directs Recruitment of the Mediator of RNA Polymerase II Transcription and Multiple Histone Acetyltransferase Complexes*♦

M. Washburn, L. Florens, R. Conaway, 2012, The Journal of Biological Chemistry.

Transcriptional Properties of Mammalian Elongin A and Its Role in Stress Response*

Joan W Conaway, Makoto Inoue, Shigetaka Kitajima, 2013, The Journal of Biological Chemistry.

Transcriptional elongation factor elongin A regulates retinoic acid-induced gene expression during neuronal differentiation.

Joan W Conaway, Makoto Inoue, Shigetaka Kitajima, 2012, Cell reports.

Identification and Characterization of a Schizosaccharomyces pombe RNA Polymerase II Elongation Factor with Similarity to the Metazoan Transcription Factor ELL*♦

Arcady Mushegian, Joan W Conaway, Michael P Washburn, 2007, Journal of Biological Chemistry.

Proteasome recruitment and activation of the Uch37 deubiquitinating enzyme by Adrm1

M. Washburn, L. Florens, R. Conaway, 2006, Nature Cell Biology.

Cloning and Characterization of ELL-associated Proteins EAP45 and EAP20

A. Shilatifard, R. Conaway, J. Conaway, 2001, The Journal of Biological Chemistry.

Mediator comes out from the shadows.

R. Conaway, J. Conaway, 2009, Structure.

The role of Mediator and Little Elongation Complex in transcription termination

Yutaka Suzuki, M. Washburn, Ichigaku Takigawa, 2020, Nature Communications.

Multiomic Analysis of the UV-Induced DNA Damage Response

A. Stewart, R. Conaway, J. Conaway, 2016, Cell reports.

Role of core promoter structure in assembly of the RNA polymerase II preinitiation complex. A common pathway for formation of preinitiation intermediates at many TATA and TATA-less promoters.

R. Conaway, J. Conaway, T. Aso, 1994, The Journal of biological chemistry.

Isolation and Characterization of the Mouse Interleukin 3 Gene and Its Expression in Activated T Cells

K. Arai, R. Conaway, J. Conaway, 1988 .

Roles for both the RAP30 and RAP74 subunits of transcription factor IIF in transcription initiation and elongation by RNA polymerase II.

R. Conaway, J. Conaway, T. Aso, 1994, The Journal of biological chemistry.

Distinct modes of regulation of the Uch37 deubiquitinating enzyme in the proteasome and in the Ino80 chromatin-remodeling complex.

M. Washburn, L. Florens, R. Conaway, 2008, Molecular cell.

Poly(ADP-ribosyl)ation directs recruitment and activation of an ATP-dependent chromatin remodeler

M. Washburn, L. Florens, R. Conaway, 2009, Proceedings of the National Academy of Sciences.

A Mammalian Chromatin Remodeling Complex with Similarities to the Yeast INO80 Complex*

Michael K. Coleman, A. Mushegian, J. Workman, 2005, Journal of Biological Chemistry.

Elongin from Saccharomyces cerevisiae *

R. Conaway, J. Conaway, C. Arrowsmith, 2000, The Journal of Biological Chemistry.

Reconstitution of G1 cyclin ubiquitination with complexes containing SCFGrr1 and Rbx1.

S. Elledge, R. Conaway, J. Conaway, 1999, Science.

Structure and Function of RNA Polymerase II Elongation Factor ELL

A. Shilatifard, R. Conaway, J. Conaway, 1997, The Journal of Biological Chemistry.

Endoplasmic Reticulum Stress-responsive Transcription Factor ATF6 Directs Recruitment of the Mediator of RNA Polymerase II Transcription and Multiple Histone

M. Washburn, L. Florens, R. Conaway, 2012 .

Subunit Composition and Substrate Specificity of a MOF-containing Histone Acetyltransferase Distinct from the Male-specific Lethal (MSL) Complex*

M. Cole, M. Washburn, L. Florens, 2009, The Journal of Biological Chemistry.

Roles of SCF and VHL ubiquitin ligases in regulation of cell growth.

R. Conaway, J. Conaway, T. Kamura, 2002, Progress in molecular and subcellular biology.

The carboxyl terminus of RAP30 is similar in sequence to region 4 of bacterial sigma factors and is required for function.

K. Arai, R. Conaway, J. Conaway, 1992, The Journal of biological chemistry.

RNA polymerase II transcription factor SIII. I. Identification, purification, and properties.

R. Conaway, J. Conaway, J. Bradsher, 1993, The Journal of biological chemistry.

The Elongin BC complex and the von Hippel-Lindau tumor suppressor protein.

R. Conaway, J. Conaway, T. Kamura, 1998, Biochimica et biophysica acta.

Regulation of the Rhp26ERCC6/CSB chromatin remodeler by a novel conserved leucine latch motif

P. Russell, J. Ranish, R. Conaway, 2014, Proceedings of the National Academy of Sciences.

Resource Multiomic Analysis of the UV-Induced DNA Damage Response Graphical Abstract Highlights

A. Stewart, R. Conaway, J. Conaway, 2022 .

Molecular cloning of an essential subunit of RNA polymerase II elongation factor SIII.

William Arbuthnot Sir Lane, R. Conaway, J. Conaway, 1994, Proceedings of the National Academy of Sciences of the United States of America.

A Molecular Basis for Stabilization of the von Hippel-Lindau (VHL) Tumor Suppressor Protein by Components of the VHL Ubiquitin Ligase*

R. Conaway, J. Conaway, C. S. Brower, 2002, The Journal of Biological Chemistry.

Characterization of Cullin-box Sequences That Direct Recruitment of Cul2-Rbx1 and Cul5-Rbx2 Modules to Elongin BC-based Ubiquitin Ligases*

William B. Redwine, M. Washburn, L. Florens, 2008, Journal of Biological Chemistry.

An RNA polymerase II transcription system from rat liver. Purification of an essential component.

R. Conaway, J. Conaway, M. Bond, 1987, The Journal of biological chemistry.

Purification of RNA polymerase II general transcription factors from rat liver.

R. Conaway, J. Conaway, K. Garrett, 1996, Methods in enzymology.

1 Mammalian Elongin A complex mediates DNA-damage-induced ubiquitylation and degradation of Rpb 1 Running title : Mammalian Elongin A complex ubiquitylates Rpb

Joan, R. Conaway, T. Aso, 2010 .

Multiple roles for PARP1 in ALC1-dependent nucleosome remodeling

M. Washburn, L. Florens, C. Tomomori-Sato, 2021, Proceedings of the National Academy of Sciences.

The mammalian Mediator complex

M. Washburn, L. Florens, T. Parmely, 2005, FEBS letters.

The inducible elongin A elongation activation domain: structure, function and interaction with the elongin BC complex.

R. Conaway, J. Conaway, R. Barstead, 1996, The EMBO journal.

CTD-dependent and -independent mechanisms govern co-transcriptional capping of Pol II transcripts

C. Tomomori-Sato, Shigeo Sato, R. Conaway, 2018, Nature Communications.

Assays for investigating the mechanism of promoter escape by RNA polymerase II.

R. Conaway, J. Conaway, A. Dvir, 2003, Methods in enzymology.

A TATA sequence‐dependent transcriptional repressor activity associated with mammalian transcription factor IIA.

R. Conaway, J. Conaway, T. Aso, 1994, The EMBO journal.

Transcription initiated by RNA polymerase II and transcription factors from liver. Structure and action of transcription factors epsilon and tau.

R. Conaway, J. Conaway, K. Garrett, 1991, The Journal of biological chemistry.

The Elongin B Ubiquitin Homology Domain

A. Shilatifard, R. Conaway, J. Conaway, 1999, The Journal of Biological Chemistry.

Promoter Escape by RNA Polymerase II

R. Conaway, J. Conaway, A. Dvir, 1997, The Journal of Biological Chemistry.

Characterization of Elongin C Functional Domains Required for Interaction with Elongin B and Activation of Elongin A*

R. Conaway, J. Conaway, Y. Takagi, 1996, The Journal of Biological Chemistry.

A Mammalian Mediator Subunit that Shares Properties with Saccharomyces cerevisiae Mediator Subunit Cse2*

M. Washburn, L. Florens, B. Zybailov, 2004, Journal of Biological Chemistry.

Crosstalk between NSL Histone Acetyltransferase and MLL/SET Complexes: NSL Complex Functions in Promoting Histone H3K4 Di-Methylation Activity by MLL/SET Complexes

R. Conaway, J. Conaway, Yong Cai, 2013, PLoS genetics.

Role for Human Mediator Subunit MED25 in Recruitment of Mediator to Promoters by Endoplasmic Reticulum Stress-responsive Transcription Factor ATF6α*

M. Washburn, L. Florens, R. Conaway, 2013, The Journal of Biological Chemistry.

Binding of elongin A or a von Hippel-Lindau peptide stabilizes the structure of yeast elongin C.

R. Conaway, J. Conaway, C. Arrowsmith, 1999, Proceedings of the National Academy of Sciences of the United States of America.

ASB2 Is an Elongin BC-interacting Protein That Can Assemble with Cullin 5 and Rbx1 to Reconstitute an E3 Ubiquitin Ligase Complex*

Arndt Benecke, Charles A. Banks, R. Conaway, 2005, Journal of Biological Chemistry.

Both BC-Box Motifs of Adenovirus Protein E4orf6 Are Required To Efficiently Assemble an E3 Ligase Complex That Degrades p53

Paola Blanchette, Philip E. Branton, R. Conaway, 2004, Molecular and Cellular Biology.

Mechanism of promoter selection by RNA polymerase II: Mammalian transcription factors a and fry promote entry of polymerase into the preinitiation complex

R. Conaway, J. Conaway, K. Garrett, 2022 .

Faculty Opinions recommendation of FIH-1: a novel protein that interacts with HIF-1alpha and VHL to mediate repression of HIF-1 transcriptional activity.

R. Conaway, 2001 .

Assembly of the Mediator-RNA polymerase II holoenzyme 1 Role for the MED 21-MED 7 hinge in assembly of the Mediator-RNA polymerase II holoenzyme

Mihaela E. Sardiu, M. Washburn, L. Florens, 2016 .

Initiation of eukaryotic messenger RNA synthesis.

R. Conaway, J. Conaway, 1991, The Journal of biological chemistry.

The von Hippel-Lindau tumor suppressor complex and regulation of hypoxia-inducible transcription.

R. Conaway, J. Conaway, 2002, Advances in cancer research.

Distinct ubiquitin ligases act sequentially for RNA polymerase II polyubiquitylation

R. Conaway, J. Conaway, J. Svejstrup, 2009, Proceedings of the National Academy of Sciences.

A Unified Nomenclature for Protein Subunits of Mediator Complexes Conserved from Fungi to Humans: Med6/pmc5/arc/ Drip33/trap32, Med7/arc/drip/trap34/crsp33, Linking Transcriptional Regulators to Rna Polymerase Ii Arc/crsp/drip150/trap170, Soh1/trap18 (note That Soh1 Has Not Been yet Identified in Pu

F. Holstege, S. W. Emmons, A. Hinnebusch, 2022 .

Identification of Elongin C Sequences Required for Interaction with the von Hippel-Lindau Tumor Suppressor Protein*

R. Conaway, J. Conaway, A. Pause, 1997, The Journal of Biological Chemistry.

The tumour antigen PRAME is a subunit of a Cul2 ubiquitin ligase and associates with active NFY promoters

H. Stunnenberg, M. Washburn, L. Florens, 2011, The EMBO journal.

Distinct modes of regulation of the Uch37 deubiquitinating enzyme in the proteasome and in the Ino80 chromatin-remodeling complex.

M. Washburn, L. Florens, R. Conaway, 2008, Molecular cell.

A Role for FACT in RNA Polymerase II Promoter-Proximal Pausing.

J. Zeitlinger, M. Blanchette, R. Conaway, 2019, Cell reports.

The hunt for RNA polymerase II elongation factors: a historical perspective

R. Conaway, J. Conaway, 2019, Nature Structural & Molecular Biology.

An oligomeric form of the large subunit of transcription factor (TF) IIE activates phosphorylation of the RNA polymerase II carboxyl-terminal domain by TFIIH.

R. Conaway, J. Conaway, H. Serizawa, 1994, The Journal of biological chemistry.

Subunit Composition and Substrate Specificity of a MOF-containing Histone Acetyltransferase Distinct from the Male-specific Lethal (MSL) Complex*

M. Cole, M. Washburn, L. Florens, 2009, The Journal of Biological Chemistry.