D. K. Treiber

发表

A quantitative analysis of kinase inhibitor selectivity

Mindy I. Davis, L. Wodicka, P. Zarrinkar, 2008, Nature Biotechnology.

Comprehensive analysis of kinase inhibitor selectivity

Mindy I. Davis, L. Wodicka, P. Zarrinkar, 2011, Nature Biotechnology.

A small molecule–kinase interaction map for clinical kinase inhibitors

L. Wodicka, D. Lockhart, P. Zarrinkar, 2005, Nature Biotechnology.

Progress towards a public chemogenomic set for protein kinases and a call for contributions

Stephen J. Capuzzi, T. Willson, Mathias Frederiksen, 2017, bioRxiv.

Kinetic intermediates trapped by native interactions in RNA folding.

P. Zarrinkar, D. K. Treiber, J. Williamson, 1998, Science.

Exposing the kinetic traps in RNA folding.

D. K. Treiber, J. Williamson, James R. Williamson, 1999, Current opinion in structural biology.

Dual kinase-bromodomain inhibitors for rationally designed polypharmacology

L. Wodicka, S. Knapp, O. Fedorov, 2014, Nature chemical biology.

Fast folding mutants of the Tetrahymena group I ribozyme reveal a rugged folding energy landscape.

D. K. Treiber, J. Williamson, M. S. Rook, 1998, Journal of molecular biology.

Ins and outs of kinase DFG motifs.

D. K. Treiber, N. Shah, 2013, Chemistry & biology.

The role of damaged DNA recognition proteins in the genotoxicities of ultraviolet light and the anticancer drug cisplatin

D. K. Treiber, 1993 .

Characterization of a DNA damage-recognition protein from mammalian cells that binds specifically to intrastrand d(GpG) and d(ApG) DNA adducts of the anticancer drug cisplatin.

D. K. Treiber, S. Lippard, J. Essigmann, 1990, Biochemistry.

The Kinase Chemogenomic Set (KCGS): An Open Science Resource for Kinase Vulnerability Identification

T. Willson, Mathias Frederiksen, S. Knapp, 2019, bioRxiv.

Response to Molecule–kinase interaction map

D. Lockhart, P. Zarrinkar, D. K. Treiber, 2005, Nature Biotechnology.

An ultraviolet light-damaged DNA recognition protein absent in xeroderma pigmentosum group E cells binds selectively to pyrimidine (6-4) pyrimidone photoproducts.

D. K. Treiber, J. Essigmann, Z. Chen, 1992, Nucleic acids research.

Identification of a Chemical Probe for Family VIII Bromodomains through Optimization of a Fragment Hit.

S. Knapp, O. Fedorov, M. Bunnage, 2016, Journal of medicinal chemistry.

Reply to BIRB-796 is not an effective ABL(T315I) inhibitor

D. Lockhart, P. Zarrinkar, D. K. Treiber, 2005, Nature Biotechnology.

Novel series of pyrrolotriazine analogs as highly potent pan-Aurora kinase inhibitors.

D. K. Treiber, Zdravko V. Milanov, R. Armstrong, 2011, Bioorganic & medicinal chemistry letters.

Donated chemical probes for open science

Anton Simeonov, Steve Hitchcock, Stefan Laufer, 2018, eLife.

Structure of the kinase domain of an imatinib-resistant Abl mutant in complex with the Aurora kinase inhibitor VX-680.

Daniel K. Treiber, John Kuriyan, David J. Lockhart, 2006, Cancer research.

Inhibition of drug-resistant mutants of ABL, KIT, and EGF receptor kinases.

William Pao, Harold Varmus, Daniel K Treiber, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Discovery of AC710, a Globally Selective Inhibitor of Platelet-Derived Growth Factor Receptor-Family Kinases.

D. K. Treiber, Brian T. Campbell, R. Armstrong, 2012, ACS medicinal chemistry letters.

An optimal Mg(2+) concentration for kinetic folding of the tetrahymena ribozyme.

D. K. Treiber, J. Williamson, M. S. Rook, 1999, Proceedings of the National Academy of Sciences of the United States of America.

Activation state-dependent binding of small molecule kinase inhibitors: structural insights from biochemistry.

Daniel K Treiber, Mindy I. Davis, L. Wodicka, 2010, Chemistry & biology.

Beyond kinetic traps in RNA folding.

D. K. Treiber, J. Williamson, J R Williamson, 2001, Current opinion in structural biology.

Cisplatin-DNA adducts are molecular decoys for the ribosomal RNA transcription factor hUBF (human upstream binding factor).

D. K. Treiber, J. Essigmann, H. Jantzen, 1994, Proceedings of the National Academy of Sciences of the United States of America.

A CCHC metal‐binding domain in Nanos is essential for translational regulation

D. Curtis, R. Lehmann, P. Zamore, 1997, The EMBO journal.

Utilizing comprehensive and mini-kinome panels to optimize the selectivity of quinoline inhibitors for cyclin G associated kinase (GAK).

D. K. Treiber, W. Zuercher, C. Asquith, 2019, Bioorganic & medicinal chemistry letters.

Kinetic oligonucleotide hybridization for monitoring kinetic folding of large RNAs.

D. K. Treiber, J. Williamson, 2000, Methods in enzymology.

Utilizing comprehensive and mini-kinome panels to optimize the selectivity of quinoline inhibitors for cyclin G associated kinase (GAK)

D. K. Treiber, W. Zuercher, C. Asquith, 2018, bioRxiv.

Abstract 5387: Dual kinase/bromodomain inhibitors for rationally designed polypharmacology

L. Wodicka, S. Knapp, O. Fedorov, 2014 .