J. T. Metz

发表

Navigating the kinome.

P. Hajduk, J. T. Metz, Eric F. Johnson, 2011, Nature chemical biology.

Rational approaches to targeted polypharmacology: creating and navigating protein-ligand interaction networks.

P. Hajduk, J. T. Metz, 2010, Current opinion in chemical biology.

Assignments of 31P NMR resonances in oligodeoxyribonucleotides: origin of sequence-specific variations in the deoxyribose phosphate backbone conformation and the 31P chemical shifts of double-helical nucleic acids.

D. Gorenstein, J. T. Metz, V. Roongta, 1988, Biochemistry.

Evolving molecules using multi-objective optimization: applying to ADME/Tox.

Sean Ekins, S. Ekins, J. T. Metz, 2010, Drug discovery today.

Ligand efficiency indices as guideposts for drug discovery.

J. T. Metz, C. Abad-Zapatero, Cele Abad-Zapatero, 2005, Drug discovery today.

Theoretical studies of stereoselective hydroborations

M. Paddon-Row, K. Houk, J. T. Metz, 1984 .

Theory and modeling of stereoselective organic reactions.

M. Paddon-Row, Y. Li, D. Spellmeyer, 1986, Science.

Enhancement of chemical rules for predicting compound reactivity towards protein thiol groups

Jeffrey R. Huth, Philip J. Hajduk, James T. Metz, 2007, J. Comput. Aided Mol. Des..

Non-amidine-containing 1,2-dibenzamidobenzene inhibitors of human factor Xa with potent anticoagulant and antithrombotic activity.

J. T. Metz, J. Masters, T. Craft, 2000, Journal of medicinal chemistry.

Application of Belief Theory to Similarity Data Fusion for Use in Analog Searching and Lead Hopping

Yvonne C. Martin, Steven W. Muchmore, Scott P. Brown, 2008, J. Chem. Inf. Model..

Algorithms for network analysis in systems-ADME/Tox using the MetaCore and MetaDrug platforms

T. Nikolskaya, Y. Nikolsky, S. Ekins, 2006, Xenobiotica; the fate of foreign compounds in biological systems.

P NMR AND TWO-DIMENSIONAL NMR SPECTRA OF NUCLEIC ACIDS AND 2D NOESY-CONSTRAINED MOLECULAR MECHANICS CALCULATIONS FOR STRUCTURAL SOLUTION OF DUPLEX OLIGONUCLEOTIDES*

D. Gorenstein, J. T. Metz, V. Roongta, 2007 .

ALOHA: a novel probability fusion approach for scoring multi-parameter drug-likeness during the lead optimization stage of drug discovery

Steven W. Muchmore, Rishi R. Gupta, Robert J. Gregg, 2013, Journal of Computer-Aided Molecular Design.

Topography-biased compound library design: the shape of things to come?

Irini Akritopoulou-Zanze, J. T. Metz, I. Akritopoulou‐Zanze, 2007, Drug discovery today.

Multiobjective Optimization for Drug Discovery

Sean Ekins, J. Dana Honeycutt, James T. Metz, 2010 .