P. Courtoy

J. Renauld, S. Constantinescu, P. Courtoy, 2012, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Azithromycin, a lysosomotropic antibiotic, has distinct effects on fluid-phase and receptor-mediated endocytosis, but does not impair phagocytosis in J774 macrophages.

Marcel Mettlen, P. Courtoy, P. van der Smissen, 2002, Experimental cell research.

A fluorescent radioiodinated oligonucleotidic photoaffinity probe for protein labeling: synthesis and photolabeling of thrombin.

P. Courtoy, E. Sonveaux, C. Berens, 1999, Bioconjugate chemistry.

Time course of pathogenic and adaptation mechanisms in cystinotic mouse kidneys.

P. Courtoy, C. Antignac, E. Levtchenko, 2014, Journal of the American Society of Nephrology : JASN.

Restoring the association of the T cell receptor with CD8 reverses anergy in human tumor-infiltrating lymphocytes.

P. Courtoy, T. Boon, P. van der Smissen, 2008, Immunity.

Selective internalization of the apical plasma membrane and rapid redistribution of lysosomal enzymes and mannose 6-phosphate receptors during osteoclast inactivation by calcitonin.

R. Baron, P. Courtoy, L. Neff, 1990, Journal of cell science.

Menstrual breakdown of human endometrium can be mimicked in vitro and is selectively and reversibly blocked by inhibitors of matrix metalloproteinases.

P. Courtoy, E. Marbaix, P. Moulin, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Hormone-Resistant ProstateCancerCells and ConferResistance toApoptosis

P. Courtoy, B. Tombal, N. Zanou, 2013 .

Reciprocal epithelial:endothelial paracrine interactions during thyroid development govern follicular organization and C-cells differentiation.

P. Courtoy, O. Feron, J. Collet, 2013, Developmental biology.

Mechanism of primitive duct formation in the pancreas and submandibular glands: a role for SDF-1

P. Courtoy, P. Vanderhaeghen, G. Rousseau, 2009, BMC Developmental Biology.

Occurrence of an HIV‐1 gp160 endoproteolytic activity in low‐density vesicles and evidence for a distinct density distribution from endogenously expressed furin and PC7/LPC convertases

N. Seidah, P. Courtoy, J. Ruysschaert, 1999, FEBS letters.

Furin and proprotein convertase 7 (PC7)/lymphoma PC endogenously expressed in rat liver can be resolved into distinct post-Golgi compartments.

P. Courtoy, J. Ruysschaert, E. Decroly, 1998, Biochemical Journal.

Identification of a specific epitope on the extracellular domain of the LDL-receptor of Trypanosoma brucei brucei.

I. Coppens, F. Opperdoes, P. Courtoy, 1994, Molecular and biochemical parasitology.

Comparison of the effects of hypertonic sucrose and intracellular potassium depletion on growth hormone receptor binding kinetics and down-regulation in IM-9 cells: evidence for a sequential block of receptor--mediated endocytosis.

P. Courtoy, P. De Meyts, M. Ilondo, 1991, Endocrinology.

1 – Molecular Interactions between Colloidal Gold, Proteins, and Living Cells

P. Courtoy, P. Baudhuin, S. Beauvois, 1989 .

Lack of cadherins Celsr2 and Celsr3 impairs ependymal ciliogenesis, leading to fatal hydrocephalus

T. Uemura, P. Courtoy, M. Montcouquiol, 2010, Nature Neuroscience.

Vps34/PI3KC3 deletion in kidney proximal tubules impairs apical trafficking and blocks autophagic flux, causing a Fanconi-like syndrome and renal insufficiency

P. Courtoy, B. Vanhaesebroeck, F. Jouret, 2018, Scientific Reports.

Vps 34 / PI 3 KC 3 deletion in kidney proximal tubules impairs apical trafficking and blocks autophagic flux , causing a Fanconi-like syndrome and renal insufficiency

P. Courtoy, B. Vanhaesebroeck, F. Jouret, 2018 .

Lactacystin decreases amyloid‐β peptide production by inhibiting β‐secretase activity

P. Courtoy, J. Octave, F. N'kuli, 2006, Journal of neuroscience research.

Polymeric IgA and Galactose-Specific Pathways in Rat Hepatocytes: Evidence for Intracellular Ligand Sorting

P. Courtoy, P. Baudhuin, C. De Roe, 1985 .

Relations between plasma membrane and lysosomal membrane. 1. Fate of covalently labelled plasma membrane protein.

P. Courtoy, P. Baudhuin, J. Quintart, 1987, European journal of biochemistry.

Marker enzymes in rat liver vesicles involved in transcellular transport.

P. Courtoy, P. Baudhuin, J. Quintart, 1989, European journal of biochemistry.

Receptor-mediated endocytosis of polymeric IgA and galactosylated serum albumin in rat liver. Evidence for intracellular ligand sorting and identification of distinct endosomal compartments.

P. Courtoy, Y. Schneider, J. Limet, 1985, European journal of biochemistry.

Cholesterol segregates into submicrometric domains at the living erythrocyte membrane: evidence and regulation

P. Courtoy, M. Veiga-da-Cunha, P. van der Smissen, 2015, Cellular and Molecular Life Sciences.

Natural ceramide is unable to escape the lysosome, in contrast to a fluorescent analogue

P. Courtoy, R. Salvayre, S. Gatt, 1998, FEBS letters.

v-Src induces constitutive macropinocytosis in rat fibroblasts.

P. Courtoy, P. Baudhuin, P. Cupers, 1996, Journal of cell science.

Intracellular routing and inhibitory activity of oligonucleopeptides containing a KDEL motif.

P. Courtoy, M. Monsigny, C. Pichon, 1997, Molecular pharmacology.

An M(r) 145,000 low-density lipoprotein (LDL)-binding protein is conserved throughout the Kinetoplastida order.

F. Opperdoes, P. Courtoy, J. Raper, 1996, Molecular and biochemical parasitology.

Activity, pharmacological inhibition and biological regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase in Trypanosoma brucei.

I. Coppens, P. Courtoy, T. Levade, 1995, Molecular and biochemical parasitology.

Metalloproteinase-dependent shedding of low-density lipoprotein receptor-related protein-1 ectodomain decreases endocytic clearance of endometrial matrix metalloproteinase-2 and -9 at menstruation.

P. Courtoy, P. Henriet, H. Emonard, 2009, Endocrinology.

The endocytic catalysts, Rab5a and Rab7, are tandem regulators of thyroid hormone production

P. Courtoy, C. Daumerie, M. van den Hove, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Retrieved constituents of large dense-cored vesicles and synaptic vesicles intermix in stimulation-induced early endosomes of noradrenergic neurons.

P. Courtoy, P. Baudhuin, J. Quatacker, 1998, Journal of cell science.

Host Plasma Low Density Lipoprotein Particles as an Essential Source of Lipids for the Bloodstream Forms of Trypanosoma brucei(*)

I. Coppens, P. Courtoy, T. Levade, 1995, The Journal of Biological Chemistry.

A TRIBUTE TO Professor Christian de Duve on his 90th birthday

P. Courtoy, 2007, Journal of cellular and molecular medicine.

What's new in the importance of receptors in pathology?

M. Dietel, P. Courtoy, J. Boonstra, 1988, Pathology, research and practice.

A mouse model suggests two mechanisms for thyroid alterations in infantile cystinosis: decreased thyroglobulin synthesis due to endoplasmic reticulum stress/unfolded protein response and impaired lysosomal processing.

P. Courtoy, C. Antignac, S. Cherqui, 2015, Endocrinology.

Polymeric IgA Binding to the Human pIgR Elicits Intracellular Signalling, but Fails to Stimulate pIgR‐Transcytosis

P. Courtoy, J. Vaerman, D. Giffroy, 2001, Scandinavian journal of immunology.

In vivo stimulation of polymeric Ig receptor transcytosis by circulating polymeric IgA in rat liver.

P. Courtoy, M. Maurice, B. Lardeux, 1998, International immunology.

Regulation of matrix metalloproteinase-9/gelatinase B expression and activation by ovarian steroids and LEFTY-A/endometrial bleeding-associated factor in the human endometrium.

P. Courtoy, P. Henriet, E. Marbaix, 2005, The Journal of clinical endocrinology and metabolism.

Regulation of matrix metalloproteinase-9/gelatinase B expression and activation by ovarian steroids and LEFTY-A/EBAF in the human endometrium *

P. Courtoy, P. Henriet, E. Marbaix, 2004 .

Paracrine stimulation of interstitial collagenase (MMP-1) in the human endometrium by interleukin 1alpha and its dual block by ovarian steroids.

P. Courtoy, C. Singer, E. Marbaix, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Progesterone regulates the activity of collagenase and related gelatinases A and B in human endometrial explants.

P. Courtoy, E. Marbaix, J. Donnez, 1992, Proceedings of the National Academy of Sciences of the United States of America.

Thrombopoietin receptor activation by myeloproliferative neoplasm associated calreticulin mutants.

C. Pecquet, P. Courtoy, W. Vainchenker, 2016, Blood.

Thyrotropin activates guanosine 5'-diphosphate/guanosine 5'-triphosphate exchange on the rate-limiting endocytic catalyst, Rab5a, in human thyrocytes in vivo and in vitro.

P. Courtoy, D. Tyteca, P. de Diesbach, 2007, The Journal of clinical endocrinology and metabolism.

Thyrotropin Activates Guanosine 5 (cid:1) -Diphosphate/Guanosine 5 (cid:1) -Triphosphate Exchange on the Rate-Limiting Endocytic Catalyst, Rab5a, in Human Thyrocytes in Vivo and in Vitro

P. Courtoy, D. Tyteca, C. Selvais, 2007 .

Syndecan Recyling Is Controlled by Syntenin-PIP 2 Interaction and Arf6

P. Courtoy, P. Zimmermann, G. David, 2005 .

Syndecan recycling is controlled by syntenin-PIP2 interaction and Arf6 (vol 9, pg 377, 2005)

P. Courtoy, P. Zimmermann, F. N'kuli, 2005 .

Polarized secretion of lysosomal enzymes: co-distribution of cation- independent mannose-6-phosphate receptors and lysosomal enzymes along the osteoclast exocytic pathway

R. Baron, P. Courtoy, L. Neff, 1988, The Journal of cell biology.

12 MEMBRANE PATHWAYS IN PLASMA CELLS AND MYELOMA CELLS lysosomes

P. Courtoy, M. Farquhar, Peter D. Oq, 2003 .

Azithromycin, a lysosomotropic antibiotic, impairs fluid-phase pinocytosis in cultured fibroblasts.

P. Courtoy, P. van der Smissen, M. Mingeot-Leclercq, 2001, European journal of cell biology.

Interaction of the macrolide azithromycin with phospholipids. I. Inhibition of lysosomal phospholipase A1 activity.

P. Courtoy, P. Tulkens, M. Mingeot-Leclercq, 1996, European journal of pharmacology.

Interleukin-1 receptor-ligand interactions modulate interstitial collagenase-1 production by human endometrial fibroblasts.

P. Courtoy, C. Singer, E. Marbaix, 1999, Molecular human reproduction.

Local cytokines induce differential expression of matrix metalloproteinases but not their tissue inhibitors in human endometrial fibroblasts.

P. Courtoy, C. Singer, E. Marbaix, 1999, European journal of biochemistry.

Regulation and restricted expression of interstitial collagenase suggest a pivotal role in the initiation of menstruation.

P. Courtoy, E. Marbaix, J. Donnez, 1996, Human reproduction.

Amyloid precursor protein controls cholesterol turnover needed for neuronal activity

Jean-Baptiste Demoulin, Donatienne Tyteca, Dominique Campion, 2013, EMBO molecular medicine.

In vivo perimenstrual activation of progelatinase B (proMMP-9) in the human endometrium and its dependence on stromelysin 1 (MMP-3) ex vivo.

P. Courtoy, E. Marbaix, P. Lemoine, 2001, The Biochemical journal.

Circulating sex hormones and endometrial stromelysin-1 (matrix metalloproteinase-3) at the start of bleeding episodes in levonorgestrel-implant users.

P. Courtoy, P. Henriet, D. Dubois, 2000, Human reproduction.

Metalloproteinase-dependent shedding of LRP-1 ectodomain decreases endocytic clearance of endometrial matrix metalloproteinases-2 and -9 at menstruation Abbreviated title. Regulation of Endometrial LRP-1 Shedding

P. Courtoy, P. Henriet, H. Emonard, 2009 .

Segregation of Fluorescent Membrane Lipids into Distinct Micrometric Domains: Evidence for Phase Compartmentation of Natural Lipids?

P. Courtoy, P. van der Smissen, D. Tyteca, 2011, PloS one.

Protection of Cystinotic Mice by Kidney-Specific Megalin Ablation Supports an Endocytosis-Based Mechanism for Nephropathic Cystinosis Progression.

P. Courtoy, C. Antignac, F. Jouret, 2019, Journal of the American Society of Nephrology : JASN.

Automated morphometric estimation of liver steatosis.

L. Arnould, P. Courtoy, J. P. Cosyn, 1979, Microscopica acta. Supplement.

Studying nonobstructive azoospermia in cystinosis: histologic examination of testes and epididymis and sperm analysis in a Ctns⁻/⁻ mouse model.

P. Courtoy, C. Antignac, O. Devuyst, 2012, Fertility and sterility.

The macrolide antibiotic azithromycin interacts with lipids and affects membrane organization and fluidity: Studies on langmuir-blodgett monolayers, liposomes and J774 macrophages

P. Courtoy, Y. Dufrêne, P. Tulkens, 2003, The Journal of Membrane Biology.

Class III PI3K Vps34 Controls Thyroid Hormone Production by Regulating Thyroglobulin Iodination, Lysosomal Proteolysis, and Tissue Homeostasis

P. Courtoy, B. Vanhaesebroeck, C. Maenhaut, 2020 .

Vps34 PI 3-kinase controls thyroid hormone production by regulating thyroglobulin iodination, lysosomal proteolysis and tissue homeostasis.

P. Courtoy, B. Vanhaesebroeck, C. Maenhaut, 2020, Thyroid : official journal of the American Thyroid Association.

Expression and role of Bcl-2 in rat blastocysts exposed to high D-glucose.

P. Courtoy, P. van der Smissen, H. Alexandre, 2001, Diabetes.

Analytical subcellular fractionation of endosomal compartments in rat hepatocytes.

P. Courtoy, 1993, Sub-cellular biochemistry.

Cell cholesterol modulates metalloproteinase‐dependent shedding of low‐density lipoprotein receptor‐related protein‐1 (LRP‐1) and clearance function

A. Noël, P. Courtoy, G. Perrot, 2011, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Role of oxidative stress in lysosomal membrane permeabilization and apoptosis induced by gentamicin, an aminoglycoside antibiotic.

P. Courtoy, J. Marchand-Brynaert, P. Tulkens, 2011, Free radical biology & medicine.

Vps34 PI 3-kinase controls thyroid hormone production by regulating thyroglobulin iodination, lysosomal proteolysis and tissue homeostasis

P. Courtoy, B. Vanhaesebroeck, C. Maenhaut, 2019, bioRxiv.

Vps34 PI 3-kinase controls thyroid hormone production by regulating thyroglobulin iodination, lysosomal proteolysis and tissue homeostasis

P. Courtoy, B. Vanhaesebroeck, C. Maenhaut, 2019, bioRxiv.

Endocytosis provides a major alternative pathway for lysosomal biogenesis in kidney proximal tubular cells

P. Courtoy, O. Devuyst, T. Willnow, 2007, Proceedings of the National Academy of Sciences.

Production of interleukin-1alpha by human endometrial stromal cells is triggered during menses and dysfunctional bleeding and is induced in culture by epithelial interleukin-1alpha released upon ovarian steroids withdrawal.

P. Courtoy, P. Henriet, E. Marbaix, 2008, The Journal of clinical endocrinology and metabolism.

Phosphatidylinositol 3-phosphate 5-kinase (PIKfyve) is an AMPK target participating in contraction-stimulated glucose uptake in skeletal muscle.

B. Viollet, D. Vertommen, F. Dequiedt, 2013, The Biochemical journal.

Endocytosis of the somatostatin analogue, octreotide, by the proximal tubule-derived opossum kidney (OK) cell line.

P. Courtoy, F. Jamar, O. Devuyst, 2005, Kidney international.

Pathways of Polymeric IgA, Secretory Component, and Galactose-Exposing Proteins During Receptor-Mediated Endocytosis in Rat Hepatocytes: Ultrastructural Demonstration and Requirements for Intracellular Ligand Sorting

P. Courtoy, P. Baudhuin, J. N. Limet, 1985 .

In situ assay of acid sphingomyelinase and ceramidase based on LDL-mediated lysosomal targeting of ceramide-labeled sphingomyelin.

P. Courtoy, R. Salvayre, T. Levade, 1996, Journal of lipid research.

Binding of matrilysin-1 to human epithelial cells promotes its activity

P. Courtoy, P. Henriet, H. Emonard, 2007, Cellular and Molecular Life Sciences.

Intracellular Sorting of Galactosylated Proteins and Polymeric Iga in Rat Hepatocytes

P. Courtoy, P. Baudhuin, J. Limet, 1982 .

P. Courtoy, P. Baudhuin, D. Hoekstra, 1997, Biochemical and biophysical research communications.

Infection by Mycoplasma hyorhinis strongly enhances uptake of antisense oligonucleotides: a reassessment of receptor-mediated endocytosis in the HepG2 cell line.

P. Courtoy, M. Delmée, F. N'kuli, 2003, Nucleic acids research.

Uptake of recombinant myeloperoxidase, free or fused to Fc gamma, by macrophages enhances killing activity toward micro-organisms.

P. Courtoy, L. Maródi, A. Bollen, 1996, DNA and cell biology.

Localization and serum concentration of secretory component during massive necrosis of human liver.

P. Courtoy, M. Reynaert, J. Vaerman, 1984, Gastroenterology.

Cellular processing of growth hormone in IM-9 cells: evidence for exocytosis of internalized hormone.

P. Courtoy, P. De Meyts, M. Ilondo, 1992, Endocrinology.

Syndecan recycling [corrected] is controlled by syntenin-PIP2 interaction and Arf6.

P. Courtoy, P. Zimmermann, F. N'kuli, 2005, Developmental cell.

Presence of cellular renin-angiotensin system in chromaffin cells of bovine adrenal medulla.

L. Arckens, P. Courtoy, F. Leenen, 2002, American journal of physiology. Heart and circulatory physiology.

Characterization of the PKD 1 Gene Product, Polycystin-1

P. Courtoy, G. Germino, L. Onuchic, 2002 .

Ubiquitination of the glycosomal matrix protein receptor PEX5 in Trypanosoma brucei by PEX4 displays novel features.

P. Courtoy, D. Rigden, P. Michels, 2013, Biochimica et biophysica acta.

Contribution of Kunitz Protease Inhibitor and Transmembrane Domains to Amyloid Precursor Protein Homodimerization

J. Renauld, S. Constantinescu, P. Courtoy, 2012, Neurodegenerative Diseases.

Receptor-mediated endocytosis in the bloodstream form of Trypanosoma brucei.

I. Coppens, F. Opperdoes, P. Courtoy, 1987, The Journal of protozoology.

In vitro correction of disorders of lysosomal transport by microvesicles derived from baculovirus-infected Spodoptera cells.

P. Courtoy, T. Goss, P. van der Smissen, 2013, Molecular genetics and metabolism.

Hematopoietic Stem Cells Transplantation Can Normalize Thyroid Function in a Cystinosis Mouse Model.

P. Courtoy, S. Cherqui, P. van der Smissen, 2016, Endocrinology.

Brief Reports: Lysosomal Cross‐Correction by Hematopoietic Stem Cell‐Derived Macrophages Via Tunneling Nanotubes

P. Courtoy, S. Cherqui, C. Rocca, 2015, Stem cells.

Cystinosin is a Component of the Vacuolar H+-ATPase-Ragulator-Rag Complex Controlling Mammalian Target of Rapamycin Complex 1 Signaling.

P. Courtoy, C. Antignac, I. Guerrera, 2016, Journal of the American Society of Nephrology : JASN.

Galactose-specific endocytosis in rat liver. Biochemical and morphological characterization of a low-density compartment isolated from hepatocytes.

P. Courtoy, P. Baudhuin, J. Limet, 1983, European journal of biochemistry.

Conversion of angiotensin II into active fragments by an endosomal pathway in bovine adrenal medullary cells in primary culture.

P. Courtoy, P. Baudhuin, W. De Potter, 1995, Endocrinology.

P. Courtoy, D. Tyteca, L. D'auria, 2010, Biochimica et biophysica acta.

Synchronous increase of four acute phase proteins synthesized by the same hepatocytes during the inflammatory reaction: a combined biochemical and morphologic kinetics study in the rat.

P. Courtoy, G. Feldmann, N. Moguilevsky, 1981, Laboratory investigation; a journal of technical methods and pathology.

Exogenous and endogenous sources of sterols in the culture-adapted procyclic trypomastigotes of Trypanosoma brucei.

I. Coppens, P. Courtoy, 1995, Molecular and biochemical parasitology.

Endocytosis

P. Courtoy, A. Dautry‐Varsat, 1992, NATO ASI Series.

Receptor-mediated endocytosis of phosphodiester oligonucleotides in the HepG2 cell line: evidence for non-conventional intracellular trafficking.

Etienne Sonveaux, P. Courtoy, M. Monsigny, 2002, Nucleic acids research.

Role of acidic compartments in Trypanosoma brucei, with special reference to low-density lipoprotein processing.

I. Coppens, F. Opperdoes, P. Courtoy, 1993, Molecular and biochemical parasitology.

The loss of the chloride channel, ClC-5, delays apical iodide efflux and induces a euthyroid goiter in the mouse thyroid gland.

P. Courtoy, F. Jouret, O. Devuyst, 2006, Endocrinology.

ZONAB promotes proliferation and represses differentiation of proximal tubule epithelial cells.

P. Courtoy, P. Verroust, F. Terzi, 2010, Journal of the American Society of Nephrology : JASN.

Molecular identification of aspartate N-acetyltransferase and its mutation in hypoacetylaspartia.

P. Courtoy, F. Collard, M. Vikkula, 2009, The Biochemical journal.

Regulation of matrix metalloproteinase (MMP) activity by the low-density lipoprotein receptor-related protein (LRP). A new function for an "old friend".

Marcel Mettlen, P. Courtoy, H. Emonard, 2005, Biochimie.

Induction of post-menstrual regeneration by ovarian steroid withdrawal in the functionalis of xenografted human endometrium.

P. Courtoy, P. Henriet, E. Marbaix, 2015, Human reproduction.

Tubular proteinuria in patients with HNF1α mutations: HNF1α drives endocytosis in the proximal tubule.

P. Courtoy, M. Pontoglio, S. Garbay, 2016, Kidney international.

A Short Treatment with Galactomannan GM-CT-01 Corrects the Functions of Freshly Isolated Human Tumor–Infiltrating Lymphocytes

P. Courtoy, P. van der Smissen, K. Thielemans, 2014, Clinical Cancer Research.

A galectin-3 ligand corrects the impaired function of human CD4 and CD8 tumor-infiltrating lymphocytes and favors tumor rejection in mice.

P. Courtoy, B. Weynand, M. Moser, 2010, Cancer research.

Lysosomal enzymes in the human endometrium: a biochemical study in untreated and levonorgestrel-treated women.

P. Courtoy, E. Marbaix, P. Baudhuin, 1991, Contraception.

Constitutive macropinocytosis in oncogene-transformed fibroblasts depends on sequential permanent activation of phosphoinositide 3-kinase and phospholipase C.

P. Courtoy, U. Krause, B. Payrastre, 2000, Molecular biology of the cell.

Loss of chloride channel ClC-5 impairs endocytosis by defective trafficking of megalin and cubilin in kidney proximal tubules

P. Courtoy, P. Verroust, O. Devuyst, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Regulation and Function of LEFTY-A/EBAF in the Human Endometrium

Etienne Marbaix, Pierre J. Courtoy, K. Osteen, 2002, The Journal of Biological Chemistry.

Regulation and function of LEFTY-A/EBAF in the human endometrium. mRNA expression during the menstrual cycle, control by progesterone, and effect on matrix metalloprotineases.

K. Osteen, P. Courtoy, P. Henriet, 2002, The Journal of biological chemistry.

Focal expression and final activity of matrix metalloproteinases may explain irregular dysfunctional endometrial bleeding.

P. Courtoy, M. Berlière, D. Dubois, 2004, The American journal of pathology.

Circulating Ovarian Steroids and Endometrial Matrix Metalloproteinases (MMPs)

P. Courtoy, P. Henriet, C. Singer, 2002, Annals of the New York Academy of Sciences.

Temporal and spatial association of matrix metalloproteinases with focal endometrial breakdown and bleeding upon progestin-only contraception.

P. Courtoy, P. Henriet, E. Marbaix, 2000, The Journal of clinical endocrinology and metabolism.

The expression of interstitial collagenase in human endometrium is controlled by progesterone and by oestradiol and is related to menstruation.

P. Courtoy, P. Henriet, E. Marbaix, 1995, The Biochemical journal.

Menstrual Activity of Matrix Metalloproteinases Is Decreased in Endometrium Regenerating after Thermal Ablation

P. Courtoy, P. Henriet, E. Marbaix, 2008 .

Src Triggers Circular Ruffling and Macropinocytosis at the Apical Surface of Polarized MDCK Cells

Marcel Mettlen, P. Courtoy, P. van der Smissen, 2006, Traffic.

v-Src accelerates spontaneous motility via phosphoinositide 3-kinase, phospholipase C and phospholipase D, but abrogates chemotaxis in Rat-1 and MDCK cells

Marcel Mettlen, R. Kiss, P. Courtoy, 2004, Journal of Cell Science.

Shift of equilibrium density induced by 3,3'-diaminobenzidine cytochemistry: a new procedure for the analysis and purification of peroxidase-containing organelles

P. Courtoy, P. Baudhuin, J. Quintart, 1984, The Journal of cell biology.

Molecular Identification of NAT8 as the Enzyme That Acetylates Cysteine S-Conjugates to Mercapturic Acids*

F. Opperdoes, P. Courtoy, M. Veiga-da-Cunha, 2010, The Journal of Biological Chemistry.

Differential subcellular membrane recruitment of Src may specify its downstream signalling.

Marcel Mettlen, P. Courtoy, P. van der Smissen, 2008, Experimental cell research.

Selective Direct Toxicity of Cocaine on Fetal Mouse Neurons: Teratogenic Implications of Neurite and Apoptotic Neuronal Loss

P. Courtoy, P. Evrard, M. Nassogne, 1998, Annals of the New York Academy of Sciences.

Micrometric segregation of fluorescent membrane lipids: relevance for endogenous lipids and biogenesis in erythrocytes[S]

P. Courtoy, M. Vikkula, P. van der Smissen, 2013, Journal of Lipid Research.

Characterization of the role of the receptors PEX5 and PEX7 in the import of proteins into glycosomes of Trypanosoma brucei.

D. Vertommen, P. Courtoy, P. Michels, 2007, Biochimica et biophysica acta.

CLC-5 and KIF3B interact to facilitate CLC-5 plasma membrane expression, endocytosis, and microtubular transport: relevance to pathophysiology of Dent's disease

F. Ashcroft, P. Rorsman, P. Courtoy, 2009, American journal of physiology. Renal physiology.

Class III Phosphoinositide 3‐Kinase/VPS34 and Dynamin are Critical for Apical Endocytic Recycling

P. Courtoy, B. Vanhaesebroeck, H. Emonard, 2013, Traffic.

Uptake of lactoferrin by the liver. II. Endocytosis by sinusoidal cells.

P. Courtoy, P. Masson, N. Moguilevsky, 1984, Laboratory investigation; a journal of technical methods and pathology.

Cocaine Induces Apoptosis in Cortical Neurons of Fetal Mice

P. Courtoy, P. Evrard, J. Louahed, 1997, Journal of neurochemistry.

Janus Kinases Affect Thrombopoietin Receptor Cell Surface Localization and Stability*

S. Constantinescu, P. Courtoy, J. Staerk, 2005, Journal of Biological Chemistry.

Chloride Channels and Endocytosis: New Insights from Dent’s Disease and ClC-5 Knockout Mice

P. Courtoy, F. Jouret, O. Devuyst, 2005, Nephron Physiology.

Altered polarity and expression of H+-ATPase without ultrastructural changes in kidneys of Dent's disease patients.

P. Courtoy, P. Verroust, O. Devuyst, 2003, Kidney international.

[Pseudo-lipoma of Glisson's capsule (author's transl)].

M. Fiévez, P. Courtoy, 1978, Gastroentérologie Clinique et Biologique.

[Circulatory dynamics in mitral stenosis; physiopathologic study of 23 cases].

P. Courtoy, H. Denolin, J. Lequime, 1953, Acta cardiologica.

Ubiquitous and kidney-specific subunits of vacuolar H+-ATPase are differentially expressed during nephrogenesis.

P. Courtoy, H. Debaix, F. Jouret, 2005, Journal of the American Society of Nephrology : JASN.

AUTOIMMUNE, CHOLESTATIC AND BILIARY DISEASE A Classification of Ductal Plate Malformations Based on Distinct Pathogenic Mechanisms of Biliary Dysmorphogenesis

C. Sempoux, P. Courtoy, K. Dahan, 2011 .

Lysosome-Dependent Activation of Human Dendritic Cells by the Vaccine Adjuvant QS-21

T. Reinheckel, P. Courtoy, Abdelatif Elouahabi, 2017, Front. Immunol..

1 A short treatment with galactomannan GM-CT-01 corrects the functions of freshly isolated human tumor-infiltrating lymphocytes

P. Courtoy, P. Bruggen, K. Thielemans, 2014 .

Comparison of antigen contents in co-cultures by an in situ immunoradiometric assay.

P. Courtoy, P. Baudhuin, M. Nassogne, 1999, Biology of the cell.

The matrix metalloproteinase-1 (MMP-1) expression in the human endometrium is inversely regulated by interleukin-1 alpha and sex steroids.

P. Courtoy, C. Singer, E. Marbaix, 2000, Ceska gynekologie.

Ovarian steroids, mitogen-activated protein kinases, and/or aspartic proteinases cooperate to control endometrial remodeling by regulating gene expression in the stroma and glands.

P. Courtoy, P. Henriet, E. Marbaix, 2010, Endocrinology.

Phosphorylation of APP695 at Thr668 decreases gamma-cleavage and extracellular Abeta.

P. Courtoy, J. Octave, Nathalie Pierrot, 2007, Biochemical and biophysical research communications.

Focal cellular origin and regulation of interstitial collagenase (matrix metalloproteinase-1) are related to menstrual breakdown in the human endometrium.

P. Courtoy, P. Henriet, E. Marbaix, 1996, Journal of cell science.

Cancer Therapy : Preclinical A Short Treatment with Galactomannan GM-CT-01 Corrects the Functions of Freshly Isolated Human Tumor – In fi ltrating Lymphocytes

P. Courtoy, P. Bruggen, K. Thielemans, 2014 .

The calcium-binding protein p54/NEFA is a novel luminal resident of medial Golgi cisternae that traffics independently of mannosidase II.

P. Courtoy, K. Gevaert, A. Tartakoff, 2002, European journal of cell biology.

Cystic fibrosis is associated with a defect in apical receptor-mediated endocytosis in mouse and human kidney.

P. Lebecque, P. Courtoy, C. Hermans, 2007, Journal of the American Society of Nephrology : JASN.

GATM Mutations Cause a Dominant Fibrillar Conformational Disease in Mitochondria-When Eternity Kills.

P. Courtoy, P. Henriet, 2018, Journal of the American Society of Nephrology : JASN.

Decrease of elastic moduli of DOPC bilayers induced by a macrolide antibiotic, azithromycin.

R. Brasseur, P. Courtoy, L. Lins, 2007, Biochimica et biophysica acta.

Mechanism of the thesaurismosis and altered lysosomal dynamics induced by poly-D-glutamic acid in kidney proximal tubular cells.

P. Courtoy, P. Tulkens, P. Maldague, 1996, Laboratory investigation; a journal of technical methods and pathology.

Uptake of lactoferrin by the liver. III. Critical role of the protein moiety.

P. Courtoy, P. Masson, N. Moguilevsky, 1984, Laboratory investigation; a journal of technical methods and pathology.

Low Density Lipoprotein Receptor-related Protein Mediates Endocytic Clearance of Pro-MMP-2·TIMP-2 Complex through a Thrombospondin-independent Mechanism*

László Patthy, Etienne Marbaix, Linda Troeberg, 2004, Journal of Biological Chemistry.

A quantitative model of traffic between plasma membrane and secondary lysosomes: evaluation of inflow, lateral diffusion, and degradation

P. Courtoy, P. Baudhuin, J. Quintart, 1988, The Journal of cell biology.

Endogenous sphingomyelin segregates into submicrometric domains in the living erythrocyte membrane[S]

P. Courtoy, M. Veiga-da-Cunha, H. Mizuno, 2014, Journal of Lipid Research.

Receptors for the host low density lipoproteins on the hemoflagellate Trypanosoma brucei: purification and involvement in the growth of the parasite.

I. Coppens, F. Opperdoes, P. Courtoy, 1988, Proceedings of the National Academy of Sciences of the United States of America.

ATG24 Represses Autophagy and Differentiation and Is Essential for Homeostasy of the Flagellar Pocket in Trypanosoma brucei

P. Courtoy, D. Rigden, P. Michels, 2015, PloS one.

Trypanosoma brucei brucei: antigenic stability of its LDL receptor and immunological cross-reactivity with the LDL receptor of the mammalian host.

I. Coppens, F. Opperdoes, P. Courtoy, 1992, Experimental parasitology.

PEGylation of anti-sialoadhesin monoclonal antibodies enhances their inhibitory potencies without impairing endocytosis in mouse peritoneal macrophages.

P. Courtoy, R. Vanbever, P. Crocker, 2009, Bioconjugate chemistry.

AMP-activated protein kinase induces actin cytoskeleton reorganization in epithelial cells.

D. Vertommen, P. Courtoy, B. Sid, 2010, Biochemical and biophysical research communications.

Thyroid follicle development requires Smad1/5- and endothelial cell-dependent basement membrane assembly

Takako Sasaki, P. Courtoy, G. Bommer, 2016, Development.

Rhophilin-2 is targeted to late-endosomal structures of the vesicular machinery in the presence of activated RhoB.

B. André, P. Courtoy, I. Pirson, 2006, Experimental cell research.

Spatiotemporal coupling of focal extracellular matrix degradation and reconstruction in the menstrual human endometrium.

P. Courtoy, P. Henriet, E. Marbaix, 2009, Endocrinology.

A Unique C‐terminal Domain Allows Retention of Matrix Metalloproteinase‐27 in the Endoplasmic Reticulum

P. Courtoy, P. Henriet, E. Marbaix, 2014, Traffic.

Epithelial: Endothelial cross-talk regulates exocrine differentiation in developing pancreas.

P. Carmeliet, P. Courtoy, F. Lemaigre, 2010, Developmental biology.

Vps34/PI3KC3 deletion in kidney proximal tubules impairs apical trafficking and blocks autophagic flux, causing a Fanconi-like syndrome and renal insufficiency

P. Courtoy, B. Vanhaesebroeck, F. Jouret, 2018, Scientific Reports.

In contrast to cocaine, prenatal exposure to methadone does not produce detectable alterations in the developing mouse brain.

P. Courtoy, P. Gressens, P. Evrard, 1998, Brain research. Developmental brain research.

Regulation of Macrophage Motility by the Water Channel Aquaporin-1: Crucial Role of M0/M2 Phenotype Switch

P. Courtoy, H. Debaix, T. Nishino, 2015, PloS one.

Matrix metalloproteinase-27 is expressed in CD163+/CD206+ M2 macrophages in the cycling human endometrium and in superficial endometriotic lesions.

P. Courtoy, P. Henriet, E. Marbaix, 2014, Molecular human reproduction.

Determinants of the enzymatic activity and the subcellular localization of aspartate N-acetyltransferase.

P. Courtoy, E. Van Schaftingen, D. Tyteca, 2012, The Biochemical journal.

Coordinated behavior of mitochondria in both space and time: a reactive oxygen species-activated wave of mitochondrial depolarization.

J. V. van Beek, H. Westerhoff, K. Krab, 2004, Biophysical journal.

Analytical Subcellular Fractionation of Receptor-Mediated Transcytosis in Rat Hepatocytes

P. Courtoy, P. Baudhuin, J. Vaerman, 1992 .

Acute ligand-independent Src activation mimics low EGF-induced EGFR surface signalling and redistribution into recycling endosomes.

P. Courtoy, D. Tyteca, P. de Diesbach, 2010, Experimental cell research.

Origin, originality, functions, subversions and molecular signalling of macropinocytosis.

Marcel Mettlen, P. Courtoy, B. Payrastre, 2002, International journal of medical microbiology : IJMM.

Response of matrix metalloproteinases and tissue inhibitors of metalloproteinases messenger ribonucleic acids to ovarian steroids in human endometrial explants mimics their gene- and phase-specific differential control in vivo.

Etienne Marbaix, P. Courtoy, P. Henriet, 2005, The Journal of clinical endocrinology and metabolism.

Biochemical characterization of bona fide polycystin-1 in vitro and in vivo.

P. Courtoy, G. Germino, L. Onuchic, 2001, American journal of kidney diseases : the official journal of the National Kidney Foundation.

Cholesterol segregates into submicrometric domains at the living erythrocyte membrane: evidence and regulation

P. Courtoy, M. Veiga-da-Cunha, M. Carquin, 2015, Cellular and Molecular Life Sciences.

Relations between plasma membrane and lysosomal membrane. 2. Quantitative evaluation of plasma membrane marker enzymes in the lysosomes.

P. Courtoy, P. Baudhuin, J. Quintart, 1987, European journal of biochemistry.

Identification, purification and partial characterisation of an oligonucleotide receptor in membranes of HepG2 cells.

P. Courtoy, M. Monsigny, E. Sonveaux, 2000, Nucleic acids research.

A rapid method purifies a glycoprotein of Mr 145,000 as the LDL receptor of Trypanosoma brucei brucei.

I. Coppens, F. Opperdoes, P. Courtoy, 1991, Biochemical and biophysical research communications.

The DAB-induced density shift: principle, validity and applications to endosomes.

P. Courtoy, P. Baudhuin, J. Quintart, 1988, Progress in clinical and biological research.

Selective neuronal toxicity of cocaine in embryonic mouse brain cocultures.

P. Courtoy, P. Evrard, M. Nassogne, 1995, Proceedings of the National Academy of Sciences of the United States of America.

Single photon emission-computed tomography (SPECT) for functional investigation of the proximal tubule in conscious mice.

François Jamar, Stanislas Pauwels, P. Courtoy, 2010, American journal of physiology. Renal physiology.

Segmental and subcellular distribution of CFTR in the kidney.

P. Courtoy, F. Jouret, O. Devuyst, 2011, Methods in molecular biology.

Cellular uptake of proMMP-2:TIMP-2 complexes by the endocytic receptor megalin/LRP-2

S. Moestrup, P. Courtoy, P. Henriet, 2017, Scientific Reports.

Molecular Aspects of the Interactions Between Protein, Colloidal Gold and Cultured-cells - Application To Galactosylated Serum-albumin and Rat Hepatocytes

P. Courtoy, P. Baudhuin, J. Quintart, 1982 .

Intra-renal and subcellular distribution of the human chloride channel, CLC-5, reveals a pathophysiological basis for Dent's disease.

P. Courtoy, O. Devuyst, R. Thakker, 1999, Human molecular genetics.

Fibronectin localization in the rat glomerulus

R. Hynes, P. Courtoy, Y. Kanwar, 1980, The Journal of cell biology.

Mice lacking renal chloride channel, CLC-5, are a model for Dent's disease, a nephrolithiasis disorder associated with defective receptor-mediated endocytosis.

Yanshu Wang, P. Courtoy, H. Wang, 2000, Human molecular genetics.

AUTOIMMUNE, CHOLESTATIC AND BILIARY DISEASE A Classification of Ductal Plate Malformations Based on Distinct Pathogenic Mechanisms of Biliary Dysmorphogenesis

C. Sempoux, P. Courtoy, K. Dahan, 2011 .

Extracellular vesicles from endothelial progenitor cells promote thyroid follicle formation

D. Vertommen, P. Courtoy, P. van der Smissen, 2018, Journal of extracellular vesicles.

Differential subcellular membrane recruitment of Src may specify its downstream signalling.

Marcel Mettlen, P. Courtoy, P. van der Smissen, 2008, Experimental cell research.

Plasma protein synthesis in experimental cirrhosis. Morphologic demonstration and functional correlations.

P. Courtoy, G. Feldmann, N. Moguilevsky, 1981, Laboratory investigation; a journal of technical methods and pathology.

LGP10D10, a Lysosomal Membrane Protein

P. Courtoy, J. Letesson, R. Wattiaux, 1992 .

Mechanism of primitive duct formation in the pancreas and submandibular glands: a role for SDF-1

P. Courtoy, P. Vanderhaeghen, G. Rousseau, 2009, BMC Developmental Biology.

Shift of equilibrium density induced by 3,3'-diaminobenzidine cytochemistry: a new procedure for the analysis and purification of peroxidase-containing organelles

P. Courtoy, P. Baudhuin, J. Quintart, 1984, The Journal of cell biology.

Ultrastructural Aspects of Trans-epithelial Transfer of Iga Through Rat-liver

P. Courtoy, P. Baudhuin, Y. Schneider, 1982 .

Association of Plasma-membrane Marker Enzymes With the Lysosomal Membrane in Cultured Rat Fibroblasts

P. Courtoy, P. Baudhuin, J. Quintart, 1983 .

Fibronectin in the microvasculature: localization in the pericyte-endothelial interstitium.

P. Courtoy, J. Boyles, P. Courtoy, 1983, Journal of ultrastructure research.

Endocytosis of the somatostatin analogue, octreotide, by the proximal tubule-derived opossum kidney (OK) cell line.

P. Courtoy, F. Jamar, O. Devuyst, 2005, Kidney international.

PEGylation of anti-sialoadhesin monoclonal antibodies enhances their inhibitory potencies without impairing endocytosis in mouse peritoneal macrophages.

P. Courtoy, R. Vanbever, P. Crocker, 2009, Bioconjugate chemistry.

Intracellular potassium depletion in IM-9 lymphocytes suppresses the slowly dissociating component of human growth hormone binding and the down-regulation of its receptors but does not affect insulin receptors.

P. Courtoy, J. Carpentier, M. Ilondo, 1986, Proceedings of the National Academy of Sciences of the United States of America.

A galectin-3 ligand corrects the impaired function of human CD4 and CD8 tumor-infiltrating lymphocytes and favors tumor rejection in mice.

P. Courtoy, B. Weynand, M. Moser, 2010, Cancer research.

Molecular Aspects of the Interactions Between Proteins and Colloidal Gold

P. Courtoy, P. Baudhuin, J. Quintart, 1984 .

P. Courtoy, C. Antignac, S. Cherqui, 2015, Endocrinology.

Menstrual activity of matrix metalloproteinases is decreased in endometrium regenerating after thermal ablation.

P. Courtoy, P. Henriet, P. Lemoine, 2009, Human reproduction.