Ashley M. Smith

发表

A missense single-nucleotide polymorphism in a gene encoding a protein tyrosine phosphatase (PTPN22) is associated with rheumatoid arthritis.

Steven J. Schrodi, Annette Lee, P. Gregersen, 2004, American journal of human genetics.

The Bruton tyrosine kinase inhibitor PCI-32765 blocks B-cell activation and is efficacious in models of autoimmune disease and B-cell malignancy

Douglas H. Thamm, Erik Verner, L. Honigberg, 2010, Proceedings of the National Academy of Sciences.

Identification of Substrates of Human Protein-tyrosine Phosphatase PTPN22*

Steven R. Williams, L. Honigberg, Ashley M. Smith, 2006, Journal of Biological Chemistry.

Targeting factor D of the alternative complement pathway reduces geographic atrophy progression secondary to age-related macular degeneration

B. Yaspan, C. Regillo, L. Honigberg, 2017, Science Translational Medicine.

Mechanistic Basis for Type 2 Long QT Syndrome Caused by KCNH2 Mutations that Disrupt Conserved Arginine Residues in the Voltage Sensor

Ashley M. Smith, C. Elayi, B. Delisle, 2013, The Journal of Membrane Biology.

Function and Physiology Lysosomal Storage Disease: Revealing Lysosomal

Sean P. Dougherty, M. Yaylaoglu, L. Honigberg, 2015 .

Identification of longitudinally dynamic biomarkers in Alzheimer’s disease cerebrospinal fluid by targeted proteomics

L. Honigberg, Ashley M. Smith, D. Arnott, 2014, Molecular Neurodegeneration.

Effect of selective LRRK2 kinase inhibition on nonhuman primate lung

Paula Katavolos, Brian K. Fiske, Reina N. Fuji, 2015, Science Translational Medicine.

Functional Studies on the IBD Susceptibility Gene IL23R Implicate Reduced Receptor Function in the Protective Genetic Variant R381Q

L. Honigberg, Ashley M. Smith, A. Phillips, 2011, PloS one.

Inhibition of IgE-mediated secretion from human basophils with a highly selective Bruton's tyrosine kinase, Btk, inhibitor.

J. Schroeder, L. Honigberg, Ashley M. Smith, 2011, International immunopharmacology.

Mechanistic Basis for Type 2 Long QT Syndrome Caused by KCNH2 Mutations that Disrupt Conserved Arginine Residues in the Voltage Sensor

Daniel C Bartos, Ashley M. Smith, C. Elayi, 2013, The Journal of Membrane Biology.

A Phase I Dose Escalation Study of the Btk Inhibitor PCI-32765 in Relapsed and Refractory B Cell Non-Hodgkin Lymphoma and Use of a Novel Fluorescent Probe Pharmacodynamic Assay.

R. Advani, Sonali M. Smith, L. Honigberg, 2009 .

Sa.94. The Selective Btk Inhibitor PCI-32765 Blocks B Cell and Mast Cell Activation and Prevents Mouse Collagen Induced Arthritis

L. Honigberg, Ashley M. Smith, J. Buggy, 2008 .