W. Muster

发表

Comparative evaluation of in silico systems for ames test mutagenicity prediction: scope and limitations.

T. Singer, Alexander Hillebrecht, W. Muster, 2011, Chemical research in toxicology.

Specific Correction of Alternative Survival Motor Neuron 2 Splicing by Small Molecules: Discovery of a Potential Novel Medicine To Treat Spinal Muscular Atrophy.

F. Metzger, E. Pinard, W. Muster, 2016, Journal of medicinal chemistry.

Skin sensitization in silico protocol.

Thomas E. Exner, G. Myatt, J. Mestres, 2020, Regulatory toxicology and pharmacology : RTP.

Mouse lymphoma thymidine kinase locus gene mutation assay: International Workshop on Genotoxicity Test Procedures Workgroup report

W. Muster, K. Harrington-Brock, M. Moore, 2000, Environmental and molecular mutagenesis.

Mouse lymphoma thymidine kinase gene mutation assay: meeting of the International Workshop on Genotoxicity Testing, San Francisco, 2005, recommendations for 24-h treatment.

Julie Clements, Masamitsu Honma, Wolfgang Muster, 2007, Mutation research.

Introducing the Concept of Virtual Control Groups into Preclinical Toxicology Animal Testing

W. Muster, F. Pognan, T. Steger-Hartmann, 2020 .

Discovery of Balovaptan, a Vasopressin 1a Receptor Antagonist for the Treatment of Autism Spectrum Disorder.

A. Bruns, C. Bissantz, E. Pinard, 2020, Journal of medicinal chemistry.

Off-targetP ML: an open source machine learning framework for off-target panel safety assessment of small molecules

G. Ecker, W. Muster, Doha Naga, 2022, Journal of Cheminformatics.

Principles and Procedures for Assessment of Acute Toxicity Incorporating In Silico Methods.

Agnes L. Karmaus, David C. Jones, G. Myatt, 2022, Computational toxicology.

Phototoxicity and photogenotoxicity of nine pyridone derivatives.

Martin Potthast, W. Muster, S. Kirchner, 2003, Mutation research.

Introducing the concept of virtual control groups into preclinical toxicology testing.

Thomas Steger-Hartmann, Alexander Amberg, Wolfgang Muster, 2020, ALTEX.

Legacy data sharing to improve drug safety assessment: the eTOX project

Anne Hersey, Søren Brunak, Anthony J. Brookes, 2017, Nature Reviews Drug Discovery.

The 3T3 neutral red uptake phototoxicity test: practical experience and implications for phototoxicity testing--the report of an ECVAM-EFPIA workshop.

V. Rogiers, W. Muster, D. Bauer, 2012, Regulatory toxicology and pharmacology : RTP.

The photomutagenicity of fluoroquinolones and other drugs.

S Albertini, W. Muster, S. Albertini, 1998, Toxicology letters.

Genotoxicity of 17 gyrase- and four mammalian topoisomerase II-poisons in prokaryotic and eukaryotic test systems.

W. Muster, S. Albertini, E. Gocke, 1995, Mutagenesis.

Standardized UV-vis spectra as the foundation for a threshold-based, integrated photosafety evaluation.

W. Muster, D. Bauer, A. De Smedt, 2014, Regulatory toxicology and pharmacology : RTP.

The synthesis and biological evaluation of A-ring substituted steroidal p-quinones

W. Muster, M. Gašić, D. Milic, 1997 .

Abstract LB-085: RG70099: A novel, highly potent dual IDO1/TDO inhibitor to reverse metabolic suppression of immune cells in the tumor micro-environment

W. Muster, C. Fischer, I. Klaman, 2016 .

Genetic toxicology in silico protocol.

Raymond R Tice, Naomi L Kruhlak, Lidiya Stavitskaya, 2019, Regulatory toxicology and pharmacology : RTP.

In silico methods combined with expert knowledge rule out mutagenic potential of pharmaceutical impurities: an industry survey.

Nigel Greene, Susanne Glowienke, James S Harvey, 2012, Regulatory toxicology and pharmacology : RTP.

Computational toxicology in drug development.

Wolfgang Muster, Lutz Müller, Alexander Breidenbach, 2008, Drug discovery today.

Mouse lymphoma thymidine kinase gene mutation assay: Follow‐up International Workshop on Genotoxicity Test Procedures, New Orleans, Louisiana, April 2000

Julie Clements, Masamitsu Honma, Wolfgang Muster, 2002, Environmental and molecular mutagenesis.

A pharma-wide approach to address the genotoxicity prediction of primary aromatic amines

Mick D. Fellows, Robert A. Jolly, Alexander Amberg, 2018, Computational Toxicology.

In silico toxicology protocols.

Tudor I. Oprea, Naomi L Kruhlak, Lidiya Stavitskaya, 2018, Regulatory toxicology and pharmacology : RTP.

Increasing the Value of Data Within a Large Pharmaceutical Company Through In Silico Models.

W. Muster, A. Brigo, Doha Naga, 2022, Methods in molecular biology.

Computational Models to Predict Toxicological Endpoints in Drug Discovery and Strategies for Data Integration

A. Brigo, W. Muster, W. Muster, 2017 .

The Use of In Silico Models Within a Large Pharmaceutical Company.

Alessandro Brigo, Wolfgang Muster, W. Muster, 2016, Methods in molecular biology.

Suitable top concentration for tests with mammalian cells: mouse lymphoma assay workgroup.

Julie Clements, Masamitsu Honma, Wolfgang Muster, 2011, Mutation research.

Mouse lymphoma thymidine kinase gene mutation assay: International Workshop on Genotoxicity Tests Workgroup report--Plymouth, UK 2002.

Isao Yoshimura, Julie Clements, Masamitsu Honma, 2003, Mutation research.

Use of in silico systems and expert knowledge for structure-based assessment of potentially mutagenic impurities.

Scott Boyer, Nigel Greene, Lutz Müller, 2013, Regulatory toxicology and pharmacology : RTP.

Strategies for Using Computational Toxicology Methods in Pharmaceutical R&D

Wolfgang Muster, Lutz Müller, Alexander Breidenbach, 2006 .

Establishing best practise in the application of expert review of mutagenicity under ICH M7.

Lidiya Stavitskaya, Alexander Amberg, Steve Gutsell, 2015, Regulatory toxicology and pharmacology : RTP.

Genotoxicity assessment of drug metabolites in the context of MIST and beyond.

W. Muster, A. Brigo, A. Sutter, 2019, Chemical research in toxicology.

Qualification of impurities based on metabolite data.

W. Muster, Chuang Lu, B. Trela, 2019, Regulatory toxicology and pharmacology : RTP.

Principles and procedures for handling out-of-domain and indeterminate results as part of ICH M7 recommended (Q)SAR analyses

Lidiya Stavitskaya, Raymond Kemper, Glenn J. Myatt, 2018, Regulatory toxicology and pharmacology : RTP.

Structure-activity relationship of oxadiazoles and allylic structures in the Ames test: an industry screening approach.

W. Muster, S. Albertini, E. Gocke, 2003, Mutagenesis.

eTRANSAFE: data science to empower translational safety assessment

N. Blomberg, M. Mayer, F. Sanz, 2023, Nature Reviews Drug Discovery.

Principles and procedures for implementation of ICH M7 recommended (Q)SAR analyses.

Lidiya Stavitskaya, Raymond Kemper, Alexander Amberg, 2016, Regulatory toxicology and pharmacology : RTP.