Andrew G Smith

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Circadian Cycling of the Mouse Liver Transcriptome, as Revealed by cDNA Microarray, Is Driven by the Suprachiasmatic Nucleus

R. Akhtar, A. B. Reddy, E. Maywood, 2002, Current Biology.

Hepatic gene expression in protoporphyic Fech mice is associated with cholestatic injury but not a marked depletion of the heme regulatory pool.

Andrew G Smith, T. Gant, D. Dinsdale, 2005, The American journal of pathology.

Associations between ultraviolet radiation, basal cell carcinoma site and histology, host characteristics, and rate of development of further tumors.

Andrew G Smith, V. Samarasinghe, J. Lear, 2005, Journal of the American Academy of Dermatology.

Defective TPA signalling compromises HaCat cells as a human in vitro skin carcinogenesis model.

Andrew G Smith, T. Gant, K. Ridd, 2010, Toxicology in vitro : an international journal published in association with BIBRA.

Toxicology of DDT and Some Analogues

Andrew G Smith, 2010 .

CHAPTER 60 – DDT and its Analogs

Andrew G Smith, 2001 .

Basal cell carcinoma

Andrew G Smith, J. Lear, C. Griffiths, 2000, Cancer.

Multiple polymorphic loci determine basal hepatic and splenic iron status in mice

K. Broman, Andrew G Smith, R. Davies, 2006, Hepatology.

B2 SINE retrotransposon causes polymorphic expression of mouse 5-aminolevulinic acid synthase 1 gene.

Andrew G Smith, R. Davies, T. Chernova, 2008, Biochemical and biophysical research communications.

Goitre and wasting induced in hamsters by hexachlorobenzene

Andrew G Smith, D. Dinsdale, A. Wright, 1987, Archives of Toxicology.

Chapter 6 Disruption of Heme Synthesis by Polyhalogenated Aromatics

Andrew G Smith, T. Chernova, 2009 .

92 – Porphyria Caused by Chlorinated AH Receptor Ligands and Associated Mechanisms of Liver Injury and Cancer

Andrew G Smith, 2003 .

Uroporphyria and hepatic carcinogenesis induced by polychlorinated biphenyls-iron interaction: absence in the Cyp1a2(-/-) knockout mouse.

Andrew G Smith, D. Nebert, R. Davies, 2005, Biochemical and biophysical research communications.

Cyp1a1(-/-) male mice: protection against high-dose TCDD-induced lethality and wasting syndrome, and resistance to intrahepatocyte lipid accumulation and uroporphyria.

Andrew G Smith, D. Nebert, P. Sinclair, 2004, Toxicology and applied pharmacology.

Mevastatin accelerates loss of synaptic proteins and neurite degeneration in aging cortical neurons in a heme-independent manner

I. Forsythe, Andrew G Smith, J. Steinert, 2010, Neurobiology of Aging.

Polymorphism in the nuclear excision repair gene ERCC2/XPD: association between an exon 6–exon 10 haplotype and susceptibility to cutaneous basal cell carcinoma

Andrew G Smith, J. Lear, R. Strange, 2005, Human mutation.

Rapid induction of hepatic fibrosis in the gerbil after the parenteral administration of iron‐dextran complex

Andrew G Smith, P. Carthew, B. Dorman, 1991, Hepatology.

Toxicology elsewhere

Andrew G Smith, R. Edwards, D. Lison, 1995 .

Seven-Year Prospective Study of Nonmelanoma Skin Cancer Incidence in U.K. Renal Transplant Recipients

Andrew G Smith, P. Harden, A. Fryer, 2007, Transplantation.

Complex gene-chemical interactions: hepatic uroporphyria as a paradigm.

Andrew G Smith, G. Elder, 2010, Chemical research in toxicology.

Essential role of the AH receptor in the dysfunction of heme metabolism induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin.

Andrew G Smith, T. Gant, R. Davies, 2008, Chemical research in toxicology.

Polychlorinated dibenzo-p-dioxins and the human immune system: 4 studies on two Spanish families with increased body burdens of highly chlorinated PCDDs.

Andrew G Smith, C. Rappe, D. Neubert, 2008, Environment international.

Complex response to physiological and drug-induced hepatic heme demand in monoallelic ALAS1 mice

Andrew G Smith, T. Chernova, S. Robinson, 2021, Molecular genetics and metabolism reports.

Complicity of haem in some adverse drug-reactions

Andrew G Smith, V. Vágány, 2015 .

Early Failure of N-Methyl-d-aspartate Receptors and Deficient Spine Formation Induced by Reduction of Regulatory Heme in Neurons

I. Forsythe, Andrew G Smith, R. Challiss, 2011, Molecular Pharmacology.

Characterization and accumulation of ferritin in hepatocyte nuclei of mice with iron overload

Andrew G Smith, D. Dinsdale, P. Carthew, 1990, Hepatology.

The Value of Skin Biopsy in Inflammatory Dermatoses

Andrew G Smith, A. Biswas, M. Stephens, 2009, The American Journal of dermatopathology.

Sebaceous hyperplasia and skin cancer in patients undergoing renal transplant.

Andrew G Smith, P. Harden, A. Fryer, 2006, Journal of the American Academy of Dermatology.

Factors associated with nonmelanoma skin cancer following renal transplantation in Queensland, Australia.

D. Nicol, Andrew G Smith, P. Harden, 2003, Journal of the American Academy of Dermatology.

Patients with both basal and squamous cell carcinomas are at a lower risk of further basal cell carcinomas than patients with only a basal cell carcinoma.

Andrew G Smith, J. Lear, R. Strange, 2009, Journal of the American Academy of Dermatology.

Associations between UVR exposure and basal cell carcinoma site and histology.

Andrew G Smith, J. Lear, C. Griffiths, 2004, Cancer letters.

PTCH polymorphism is associated with the rate of increase in basal cell carcinoma numbers during follow‐up: Preliminary data on the influence of an exon 12‐exon 23 haplotype

Andrew G Smith, J. Lear, R. Strange, 2004, Environmental and molecular mutagenesis.

Gene expression and amplification in breast carcinoma cells with intrinsic and acquired doxorubicin resistance

J. Styles, D. Lipson, Andrew G Smith, 2001, Oncogene.

Induction of iron homeostasis genes during estrogen-induced uterine growth and differentiation

G. Orphanides, J. Ashby, Andrew G Smith, 2006, Molecular and Cellular Endocrinology.

Porphyrin analysis by reversed-phase high-performance liquid chromatography: biomedical applications

Andrew G Smith, J. Francis, 1985 .

Heme Deficiency Is Associated with Senescence and Causes Suppression of N-Methyl-d-aspartate Receptor Subunits Expression in Primary Cortical Neurons

Andrew G Smith, P. Nicotera, T. Chernova, 2006, Molecular Pharmacology.

Heme Deficiency is Associated with Senescence and Causes Suppression of NMDA Receptor Subunits Expression in

Andrew G Smith, P. Nicotera, T. Chernova, 2005 .

Single-molecule PCR analysis of germ line mutation induction by anticancer drugs in mice.

Andrew G Smith, Y. Dubrova, Colin D. Glen, 2008, Cancer research.

Germline mutation induction at mouse repeat DNA loci by chemical mutagens.

Andrew G Smith, Y. Dubrova, C. Vilariño-Güell, 2003, Mutation research.

The regulatory role of heme in neurons.

Emma Lloyd Raven, Tatyana Chernova, Andrew G Smith, 2011, Metallomics : integrated biometal science.

Dealkylation during electron impact mass spectrometric analysis of N‐ monoalkylated porphyrin methyl esters

Andrew G Smith, P. Farmer, 1982 .

Carcinogenicity of iron in conjunction with a chlorinated environmental chemical, hexachlorobenzene, in c57bl/10scsn mice

Andrew G Smith, P. Carthew, M. Manson, 1989, International journal of cancer.

The association between chemical-induced porphyria and hepatic cancer

Andrew G Smith, J. Foster, 2018, Toxicology research.

Non-ahr gene susceptibility Loci for porphyria and liver injury induced by the interaction of 'dioxin' with iron overload in mice.

R. Akhtar, Andrew G Smith, M. Festing, 2002, Molecular pharmacology.

Hexachlorobenzene stimulates uroporphyria in low affinity AHR mice without increasing CYP1A2.

Andrew G Smith, S. Robinson, P. Sinclair, 2007, Toxicology and applied pharmacology.

p53 deficiency does not affect mutation rate in the mouse germline

Andrew G Smith, K. Burr, Y. Dubrova, 2005, Oncogene.

A microarray analysis of differential gene expression associated with the development of doxorubicin resistance in breast carcinoma

J. Styles, D. Lipson, Andrew G Smith, 2003 .

Association between functional polymorphism in EGF gene and malignant melanoma

Andrew G Smith, J. Lear, R. Strange, 2002, The Lancet.

The Aryl Hydrocarbon Receptor: Differential Contribution to T Helper 17 and T Cytotoxic 17 Cell Development

Andrew G Smith, I. Kimber, R. Dearman, 2014, PloS one.

Plasma levels of enoxaparin oligosaccharides, antifactor-Xa and thrombin generation in patients undergoing haemodialysis.

Andrew G Smith, M. Jose, Ritam Prasad, 2020, Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis.

Chapter 3:DDT and Other Chlorinated Insecticides

Andrew G Smith, 2012 .

Combined effects of gender, skin type and polymorphic genes on clinical phenotype: use of rate of increase in numbers of basal cell carcinomas as a model system.

Andrew G Smith, J. Lear, R. Strange, 2003, Cancer letters.

Adjuvant Sandwich Chemotherapy and Radiation Versus Adjuvant Chemotherapy Alone for Locally Advanced Bladder Cancer

Andrew G Smith, W. Hwang, J. Christodouleas, 2016 .

Vitamin D receptor polymorphisms are associated with altered prognosis in patients with malignant melanoma.

Andrew G Smith, J. Lear, R. Strange, 2000, Clinical cancer research : an official journal of the American Association for Cancer Research.

A model for nurse-led skin cancer surveillance following renal transplantation.

Andrew G Smith, P. Harden, H. Ramsay, 2002, Nephrology nursing journal : journal of the American Nephrology Nurses' Association.

Glutathione S-transferase GSTP1 and cyclin D1 genotypes: association with numbers of basal cell carcinomas in a patient subgroup at high-risk of multiple tumours.

Andrew G Smith, F. Ali-Osman, J. Lear, 2000, Pharmacogenetics.

Rapid induction of hepatic fibrosis in the gerbil after the parenteral administration of iron‐dextran complex

Andrew G Smith, P. Carthew, B. Dorman, 1991, Hepatology.

Basal cell carcinoma

Andrew G Smith, J. Lear, C. Wong, 2000, BMJ : British Medical Journal.

Neonatal tamoxifen treatment of mice leads to adenomyosis but not uterine cancer.

J. Styles, Andrew G Smith, T. Gant, 2005, Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie.

Clinical risk factors associated with nonmelanoma skin cancer in renal transplant recipients.

Andrew G Smith, P. Harden, A. Fryer, 2000, American journal of kidney diseases : the official journal of the National Kidney Foundation.

Polymorphisms in glutathione S-transferases are associated with altered risk of nonmelanoma skin cancer in renal transplant recipients: a preliminary analysis.

Andrew G Smith, P. Harden, R. Strange, 2001, The Journal of investigative dermatology.

Gene expression profiles associated with inflammation, fibrosis, and cholestasis in mouse liver after griseofulvin.

Andrew G Smith, T. Gant, R. Davies, 2002, EHP toxicogenomics : journal of the National Institute of Environmental Health Sciences.

Basal cell carcinomas: association of allelic variants with a high-risk subgroup of patients with the multiple presentation phenotype.

Andrew G Smith, J. Lear, A. Fryer, 2001, Pharmacogenetics.

Presentation with multiple cutaneous basal cell carcinomas: association of glutathione S-transferase and cytochrome P450 genotypes with clinical phenotype.

Andrew G Smith, J. Lear, A. Fryer, 1999, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.

Persistent health effects of dioxin contamination in herbicide production.

Andrew G Smith, M. Neuberger, M. Hansson, 1999, Environmental research.

Search for Ha-ras codon 61 mutations in liver tumours caused by hexachlorobenzene and Aroclor 1254 in C57BL/10ScSn mice with iron overload.

Andrew G Smith, P. Carthew, A. Smith, 1992, Carcinogenesis.

Sex-linked hepatic uroporphyria and the induction of cytochromes P450IA in rats caused by hexachlorobenzene and polyhalogenated biphenyls.

Andrew G Smith, C. Wolf, J. B. Greig, 1990, Biochemical pharmacology.

Interaction between iron metabolism and 2,3,7,8-tetrachlorodibenzo-p-dioxin in mice with variants of the Ahr gene: a hepatic oxidative mechanism.

Andrew G Smith, R. Edwards, S. Robinson, 1998, Molecular pharmacology.

The regulatory role of heme in neurons.

Andrew G Smith, T. Chernova, E. Raven, 2011, Metallomics : integrated biometal science.

Iron as a synergist for hepatocellular carcinoma induced by polychlorinated biphenyls in Ah-responsive C57BL/10ScSn mice.

Andrew G Smith, P. Carthew, A. Smith, 1990, Carcinogenesis.