B. Schäfer

发表

Inhibition of differentiation in myoblasts deprived of the interferon-related protein PC4.

D. Guardavaccaro, M. Ciotti, B. Schäfer, 1995, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.

Prediction of chromosomal aneuploidy from gene expression data

D. Notterman, S. Raimondi, E. Domany, 2007, Genes, chromosomes & cancer.

PAX3 is expressed in human melanomas and contributes to tumor cell survival.

R. Dummer, B. Schäfer, F. A. Scholl, 2001, Cancer research.

New insights to the MLL recombinome of acute leukemias

M. Krzywinski, E. Clappier, B. Schäfer, 2009, Leukemia.

PROTEINS : STRUCTURE , FUNCTIONS AND PATHOLOGY

C. Heizmann, B. Schäfer, 2002 .

S100 proteins: structure, functions and pathology.

C. Heizmann, B. Schäfer, G. Fritz, 2002, Frontiers in bioscience : a journal and virtual library.

Calcium regulation of Ndr protein kinase mediated by S100 calcium‐binding proteins

C. Heizmann, B. Schäfer, B. Hemmings, 1998, The EMBO journal.

S100A1-deficient male mice exhibit increased exploratory activity and reduced anxiety-related responses.

C. Heizmann, B. Schäfer, P. Erne, 2006, Biochimica et biophysica acta.

Repression of the candidate tumor suppressor gene S100A2 in breast cancer is mediated by site-specific hypermethylation.

C. Heizmann, B. Schäfer, F. A. Scholl, 1997, Cell calcium.

Distinct gene expression profiles determine molecular treatment response in childhood acute lymphoblastic leukemia.

Thomas Flohr, Martin Stanulla, Brigitte Schlegelberger, 2005, Blood.

Six S100 genes are clustered on human chromosome 1q21: identification of two genes coding for the two previously unreported calcium-binding proteins S100D and S100E.

C. Heizmann, B. Schäfer, P. Erne, 1993, Proceedings of the National Academy of Sciences of the United States of America.

Immunohistochemical localization of the Ca2+ binding S100 proteins in normal human skin and melanocytic lesions

C. Heizmann, B. Schäfer, R. Böni, 1997, The British journal of dermatology.

NuRD subunit CHD4 regulates super-enhancer accessibility in rhabdomyosarcoma and represents a general tumor dependency

J. Khan, B. Schäfer, M. Gstaiger, 2020, eLife.

Minimal residual disease-directed risk stratification using real-time quantitative PCR analysis of immunoglobulin and T-cell receptor gene rearrangements in the international multicenter trial AIEOP-BFM ALL 2000 for childhood acute lymphoblastic leukemia

B. Schäfer, M. Schrappe, C. Bartram, 2008, Leukemia.

Distinct subcellular localization of calcium binding S100 proteins in human smooth muscle cells and their relocation in response to rises in intracellular calcium.

D. Atar, C. Heizmann, B. Schäfer, 1998, Journal of cell science.

α-Parvalbumin reduces depolarizationminduced elevations of cytosolic free calcium in human neuroblastoma cells

C. Heizmann, B. Schäfer, T. Knöpfel, 1996 .

Expression of intracellular calcium-binding proteins in cultured skin fibroblasts from Alzheimer and normal aged donors.

C. Heizmann, B. Schäfer, G. Gibson, 1994, Biochimica et biophysica acta.

Differential expression of the Ca2+ binding S100A6 protein in normal, preneoplastic and neoplastic colon mucosa.

C. Heizmann, B. Schäfer, J. Osterreicher, 2000, European journal of cancer.

The proprotein convertase furin is required to maintain viability of alveolar rhabdomyosarcoma cells

B. Schäfer, P. Jaaks, E. Koscielniak, 2016, Oncotarget.

Differential expression of S100B and S100A6(1) in the human fetal and aged cerebral cortex.

C. Heizmann, B. Schäfer, W. Chan, 2000, Brain research. Developmental brain research.

CD133 Positive Embryonal Rhabdomyosarcoma Stem-Like Cell Population Is Enriched in Rhabdospheres

H. Moch, H. Rehrauer, B. Schäfer, 2011, PloS one.

A human POU domain gene, mPOU, is expressed in developing brain and specific adult tissues.

G. Lyons, B. Schäfer, E. Wey, 1994, European journal of biochemistry.

In vivo amplification of the PAX3-FKHR and PAX7-FKHR fusion genes in alveolar rhabdomyosarcoma.

J. Biegel, B. Schäfer, R. Davis, 1996, Human molecular genetics.

A Perspective on Polo-Like Kinase-1 Inhibition for the Treatment of Rhabdomyosarcomas

B. Schäfer, P. Kearns, S. Fulda, 2019, Front. Oncol..

Aurora A kinase inhibition destabilizes PAX3-FOXO1 and MYCN and synergizes with Navitoclax to induce Rhabdomyosarcoma cell death.

D. Surdez, O. Delattre, B. Schäfer, 2019, Cancer research.

University of Birmingham A perspective on polo-like kinase-1 inhibition for the treatment of rhabdomyosarcoma

B. Schäfer, P. Kearns, S. Fulda, 2019 .

CRISPR activation screen identifies TGFβ-associated PEG10 as a crucial tumor suppressor in Ewing sarcoma

B. Schäfer, Q. Ngo, F. Niggli, 2022, Scientific Reports.

Complementary DNA sequence and chromosomal mapping of a human proteoglycan-binding cell-adhesion protein (dermatopontin).

M. Rocchi, B. Schäfer, R. Gitzelmann, 1993, Genomics.

Single-cell mapping of tumor heterogeneity in pediatric rhabdomyosarcoma reveals developmental signatures with therapeutic relevance

P. Bühlmann, H. Blau, B. Schäfer, 2022, bioRxiv.

A combinatorial drug screen in PDX-derived primary rhabdomyosarcoma cells identifies the NOXA - BCL-XL/MCL-1 balance as target for re-sensitization to first-line therapy in recurrent tumors

B. Schäfer, P. Bode, M. Wachtel, 2021, Neoplasia.

Cannabinoid receptor 1 is a potential drug target for treatment of translocation-positive rhabdomyosarcoma

B. Schäfer, G. Velasco, M. Guzmán, 2009, Molecular Cancer Therapeutics.

Molecular features of a human rhabdomyosarcoma cell line with spontaneous metastatic progression

B. Schäfer, F. A. Scholl, D. Betts, 2000, British Journal of Cancer.

ESF-EMBO Symposium “Molecular Biology and Innovative Therapies in Sarcomas of Childhood and Adolescence” Sept 29–Oct 4, Polonia Castle Pultusk, Poland

B. Schäfer, S. Fulda, H. Kovar, 2013, Front. Oncol..

PLK1 phosphorylates PAX3-FOXO1, the inhibition of which triggers regression of alveolar Rhabdomyosarcoma.

B. Schäfer, D. Herrero-Martín, E. Koscielniak, 2015, Cancer research.

Transcriptional modulation of the anti-apoptotic protein BCL-XL by the paired box transcription factors PAX3 and PAX3/FKHR

B. Schäfer, F. Barr, C. Margue, 2000, Oncogene.

S100A1, a new marker for acute myocardial ischemia.

C. Heizmann, B. Schäfer, E. Minder, 2000, Biochemical and biophysical research communications.

Selective association of S100A6 1 According to the new nomenclature of S100 proteins [23]. 1 (calcyclin)-immunoreactive astrocytes with the tangential migration pathway of subventricular zone cells in the rat

T. Kosaka, C. Heizmann, B. Schäfer, 1997, Brain Research.

S100 protein translocation in response to extracellular S100 is mediated by receptor for advanced glycation endproducts in human endothelial cells.

C. Heizmann, B. Schäfer, Hsiao-Ling Hsieh, 2004, Biochemical and biophysical research communications.

Expression pattern of S100 calcium‐binding proteins in human tumors

C. Heizmann, B. Schäfer, E. Ilg, 1996, International journal of cancer.

Molecular testing of rhabdomyosarcoma in clinical trials to improve risk stratification and outcome: A consensus view from European paediatric Soft tissue sarcoma Study Group, Children's Oncology Group and Cooperative Weichteilsarkom-Studiengruppe.

B. Schäfer, D. Hawkins, A. Kelsey, 2022, European journal of cancer.

Identification of a rhabdomyosarcoma targeting peptide by phage display with sequence similarities to the tumour lymphatic‐homing peptide LyP‐1

B. Schäfer, H. Witt, F. Niggli, 2009, International journal of cancer.

Zooming in on an ”undruggable” target

B. Schäfer, M. Wachtel, 2018 .

Ca2+ -dependent interaction of S100A1 with the sarcoplasmic reticulum Ca2+ -ATPase2a and phospholamban in the human heart.

C. Heizmann, B. Schäfer, P. Erne, 2003, Biochemical and biophysical research communications.

Distinct gene expression proﬁles determine molecular treatment response in childhood acute lymphoblastic leukemia

B. Schäfer, C. Bartram, K. Welte, 2004 .

Cancer Stem Cells in Pediatric Sarcomas

B. Schäfer, S. Satheesha, 2014 .

Binding of Ca2+ and Zn2+ to Human Nuclear S100A2 and Mutant Proteins*

C. Heizmann, J. Cox, B. Schäfer, 1998, The Journal of Biological Chemistry.

Immunohistochemical detection of EGFR, fibrillin‐2, P‐cadherin and AP2β as biomarkers for rhabdomyosarcoma diagnostics

B. Schäfer, I. Leuschner, F. Niggli, 2009, Histopathology.

Increased expression of S100A4 and its prognostic significance in esophageal squamous cell carcinoma.

C. Heizmann, B. Schäfer, I. Ninomiya, 2001, International journal of oncology.

Telomerase Activity in Cell Lines of Pediatric Soft Tissue Sarcomas

B. Schäfer, U. Klotz, M. Schwab, 2003, Pediatric Research.

Prognostic significance of the Ca(2+) binding protein S100A2 in laryngeal squamous-cell carcinoma.

C. Heizmann, B. Schäfer, F. Michetti, 2000, International journal of cancer.

Inv(11)(p13p15) and Myf-3(MyoD1) in a Malignant Extrarenal Rhabdoid Tumor of a Premature Newborn

B. Schäfer, W. Holzgreve, F. A. Scholl, 2000, Pediatric Research.

The LIM-only protein FHL2 is a negative regulator of E4F1

B. Schäfer, C. Sardet, C. Paul, 2006, Oncogene.

Ultrastructural distribution of the S100A1 Ca2+-binding protein in the human heart.

C. Heizmann, B. Schäfer, A. Mandinova, 2001, Physiological research.

Characterization of the human S100A12 (calgranulin C, p6, CAAF1, CGRP) gene, a new member of the S100 gene cluster on chromosome 1q21.

C. Heizmann, B. Schäfer, I. Marenholz, 1996, Cell calcium.

Characterization of the human and mouse cDNAs coding for S100A13, a new member of the S100 protein family.

C. Heizmann, B. Schäfer, P. Erne, 1996, Biochemical and biophysical research communications.

Generation of a novel rtTA transgenic mouse to induce time‐controlled, tissue‐specific alterations in Pax2‐expressing cells

B. Schäfer, F. Niggli, A. Burger, 2011, Genesis.

Analysis of Ca2+-Binding S100 Proteins in Human Heart by HPLC-Electrospray Mass Spectrometry

C. Heizmann, B. Schäfer, P. Erne, 1993 .

Analysis of CA(2+)-binding S100 proteins in human heart by HPLC-electrospray mass spectrometry.

C. Heizmann, B. Schäfer, P. Erne, 1993, Biochemical and biophysical research communications.

The MLL recombinome of acute leukemias in 2017

E. Clappier, J. Cayuela, V. V. D. van der Velden, 2017, Leukemia.

Array comparative genomic hybridization reveals unbalanced gain of the MYCN region in Wilms tumors.

B. Schäfer, D. Betts, F. Niggli, 2007, Cancer genetics and cytogenetics.

Molecular Characterization of Circulating Tumor DNA in Pediatric Rhabdomyosarcoma: A Feasibility Study

D. Surdez, O. Delattre, B. Schäfer, 2022, JCO precision oncology.

Targeting the EWS-ETS transcriptional program by BET bromodomain inhibition in Ewing sarcoma

B. Schäfer, S. Burdach, F. Neff, 2015, Oncotarget.

Human recombinant alpha-parvalbumin and nine mutants with individually inactivated calcium- and magnesium-binding sites: biochemical and immunological properties.

C. Heizmann, J. Cox, B. Schäfer, 1996, Biochimica et biophysica acta.

The Ca2+-binding S100A2 protein is differentially expressed in epithelial tissue of glandular or squamous origin.

C. Heizmann, R. Kiss, B. Schäfer, 2002, Histology and histopathology.

Immunolocalization of the calcium binding S100A1, S100A5 and S100A6 proteins in the dog cochlea during postnatal development.

C. Heizmann, R. Kiss, B. Schäfer, 2001, Brain research. Developmental brain research.

The human paired domain gene PAX7 (Hup1) maps to chromosome 1p35-1p36.2.

B. Schäfer, M. Mattei, 1993, Genomics.

S100A13 and S100A6 exhibit distinct translocation pathways in endothelial cells.

C. Heizmann, J. Cox, B. Schäfer, 2002, Journal of cell science.

Isolation of a YAC clone covering a cluster of nine S100 genes on human chromosome 1q21: rationale for a new nomenclature of the S100 calcium-binding protein family.

C. Heizmann, B. Schäfer, M. Mattei, 1995, Genomics.

Expression analysis of S100 proteins and RAGE in human tumors using tissue microarrays.

C. Heizmann, B. Schäfer, Hsiao-Ling Hsieh, 2003, Biochemical and biophysical research communications.

Ca2+‐binding proteins S100A6 * and S100B in primary cutaneous melanoma

C. Heizmann, R. Dummer, B. Schäfer, 1997 .

Immunohistochemical localization of S100A1 and S100A6 in postnatally developing salivary glands of rats

C. Heizmann, B. Schäfer, Y. Takai, 1998, Histochemistry and Cell Biology.

Single-cell profiling of alveolar rhabdomyosarcoma reveals RAS pathway inhibitors as cell-fate hijackers with therapeutic relevance

P. Bühlmann, H. Blau, D. Surdez, 2023, Science advances.

Purification and Cation Binding Properties of the Recombinant Human S100 Calcium-binding Protein A3, an EF-hand Motif Protein with High Affinity for Zinc (*)

C. Heizmann, J. Cox, B. Schäfer, 1995, The Journal of Biological Chemistry.

Induction of autophagy-dependent necroptosis is required for childhood acute lymphoblastic leukemia cells to overcome glucocorticoid resistance.

B. Schäfer, M. Schrappe, J. Bourquin, 2010, The Journal of clinical investigation.

Immunohistochemical evaluation of the Ca2+-binding S-100 proteins S-100A1, S-100A2, S-100A4, S-100A6 and S-100B in salivary gland tumors

C. Heizmann, B. Schäfer, P. Shrestha, 1996 .

S100 proteins in Corpora Amylacea from normal human brain 1 1 Published on the World Wide Web on 5 May 2000.

C. Heizmann, R. Kiss, B. Schäfer, 2000, Brain Research.

Fenretinide induces a new form of dynamin-dependent cell death in pediatric sarcoma

B. Schäfer, A. Kaech, U. Ziegler, 2020, Cell Death & Differentiation.

Supratentorial Pilocytic Astrocytomas, Astrocytomas, Anaplastic Astrocytomas and Glioblastomas are Characterized by a Differential Expression of S100 Proteins

C. Heizmann, R. Kiss, B. Schäfer, 1999, Brain pathology.

Phenotypic profiling with a living biobank of primary rhabdomyosarcoma unravels disease heterogeneity and AKT sensitivity

J. Tchinda, D. Surdez, O. Delattre, 2020, Nature Communications.

PAX3-FOXO1: Zooming in on an "undruggable" target.

B. Schäfer, M. Wachtel, Marco Wachtel, 2017, Seminars in cancer biology.

Gene Expression Signatures Identify Rhabdomyosarcoma Subtypes and Detect a Novel t(2;2)(q35;p23) Translocation Fusing PAX3 to NCOA1

P. Bühlmann, M. Dettling, B. Schäfer, 2004, Cancer Research.

Combined Inhibition of Epigenetic Readers and Transcription Initiation Targets the EWS-ETS Transcriptional Program in Ewing Sarcoma

W. Weichert, U. Dirksen, B. Schäfer, 2020, Cancers.

PI3K/AKT signaling modulates transcriptional expression of EWS/FLI1 through specificity protein 1

B. Schäfer, Laura A. Lopez-Garcia, F. Niggli, 2015, Oncotarget.

Small‐molecule screen identifies modulators of EWS/FLI1 target gene expression and cell survival in Ewing's sarcoma

B. Schäfer, F. Niggli, Marco Wachtel, 2012, International journal of cancer.

Isolation of genes differentially expressed in human primary myoblasts and embryonal rhabdomyosarcoma

B. Schäfer, F. A. Scholl, M. Genini, 1996, International journal of cancer.

Subtractive cloning and characterization of DRAL, a novel LIM-domain protein down-regulated in rhabdomyosarcoma.

B. Schäfer, A. Remppis, M. Mattei, 1997, DNA and cell biology.

Comparative expression profiling identifies an in vivo target gene signature with TFAP2B as a mediator of the survival function of PAX3/FKHR

B. Schäfer, F. Niggli, M. Wachtel, 2007, Oncogene.

The PAX5 oncogene is expressed in N-type neuroblastoma cells and increases tumorigenicity of a S-type cell line.

B. Schäfer, R. Stahel, D. Betts, 2004, Carcinogenesis.

The transcriptional activator PAX3-FKHR rescues the defects of Pax3 mutant mice but induces a myogenic gain-of-function phenotype with ligand-independent activation of Met signaling in vivo.

B. Schäfer, M. Buckingham, F. Relaix, 2003, Genes & development.

Induction of apoptosis in rhabdomyosarcoma cells through down-regulation of PAX proteins.

B. Schäfer, A. Remppis, F. Rauscher, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Miswired Enhancer Logic Drives a Cancer of the Muscle Lineage

J. Khan, Jun S. Wei, B. Schäfer, 2020, iScience.

The LIM-only Protein DRAL/FHL2 Interacts with and Is a Corepressor for the Promyelocytic Leukemia Zinc Finger Protein*

J. Licht, B. Schäfer, E. Ehler, 2002, The Journal of Biological Chemistry.

childhood T-cell ALL: results of the AIEOP-BFM-ALL 2000 study Late MRD response determines relapse risk overall and in subsets of

B. Schäfer, M. Schrappe, C. Bartram, 2013 .

Late MRD response determines relapse risk overall and in subsets of childhood T-cell ALL: results of the AIEOP-BFM-ALL 2000 study.

J. V. van Dongen, B. Schäfer, M. Schrappe, 2011, Blood.

Emerging roles for PAX transcription factors in cancer biology.

B. Schäfer, 1998, General physiology and biophysics.

Subcellular targeting of metabolic enzymes to titin in heart muscle may be mediated by DRAL/FHL-2

Daniel Auerbach, Stephan Lange, B. Schäfer, 2002, Journal of Cell Science.

High Frequency of Tumor Propagating Cells in Fusion-Positive Rhabdomyosarcoma

B. Schäfer, E. Casanova, P. Bode, 2021, Genes.

Molecular cloning and characterization of the human S100A14 gene encoding a novel member of the S100 family.

I. Petersen, K. Schlüns, C. Heizmann, 2002, Genomics.

Dral Is a P53-Responsive Gene Whose Four and a Half Lim Domain Protein Product Induces Apoptosis

B. Schäfer, E. Ehler, P. Mcloughlin, 2000, The Journal of cell biology.

Is a p 53-responsive Gene Whose Four and a Half LIM Domain Protein Product Induces Apoptosis

B. Schäfer, E. Ehler, P. Mcloughlin, 2000 .

USP19 deubiquitinates EWS-FLI1 to regulate Ewing sarcoma growth

B. Schäfer, P. Jaaks, Laura A. Lopez-Garcia, 2019, Scientific Reports.

Proteasomal Degradation of the EWS-FLI1 Fusion Protein Is Regulated by a Single Lysine Residue*

B. Schäfer, Laura A. Lopez-Garcia, F. Niggli, 2016, The Journal of Biological Chemistry.

The MLL recombinome of acute leukemias

M. D. Boer, R. Pieters, R. Pieters, 2006, Leukemia.

Interfering with Hedgehog Pathway: New Avenues for Targeted Therapy in Rhabdomyosarcoma.

B. Schäfer, G. Manzella, Gabriele Manzella, 2016, Current drug targets.

pathway lymphoblastic leukemia cells to dexamethasone via an Akt-dependent Low dose arsenic trioxide sensitizes glucocorticoid-resistant acute

B. Schäfer, M. Schrappe, J. Bourquin, 2013 .

Low-dose arsenic trioxide sensitizes glucocorticoid-resistant acute lymphoblastic leukemia cells to dexamethasone via an Akt-dependent pathway.

B. Schäfer, M. Schrappe, J. Bourquin, 2007, Blood.

The MLL recombinome of acute leukemias in 2013

W. Choi, S. Bohlander, E. Clappier, 2013, Leukemia.

YAP/TAZ inhibition reduces metastatic potential of Ewing sarcoma cells

B. Schäfer, L. Kenner, M. Kauer, 2021, Oncogenesis.

Unpeaceful roles of mutant PAX proteins in cancer.

B. Schäfer, M. Wachtel, 2015, Seminars in cell & developmental biology.

Reduced-Intensity Delayed Intensification in Standard-Risk Pediatric Acute Lymphoblastic Leukemia Defined by Undetectable Minimal Residual Disease: Results of an International Randomized Trial (AIEOP-BFM ALL 2000).

B. Schäfer, M. Schrappe, C. Bartram, 2017, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Subcellular distribution of S100 proteins in tumor cells and their relocation in response to calcium activation

B. Schäfer, T. Bächi, A. Mueller, 1999, Histochemistry and Cell Biology.

Advances in Brief PAX 3 Is Expressed in Human Melanomas and Contributes to Tumor Cell Survival 1

R. Dummer, B. Schäfer, F. A. Scholl, 2001 .

Immunohistochemical detection of PAX-FOXO1 fusion proteins in alveolar rhabdomyosarcoma using breakpoint specific monoclonal antibodies

P. Meltzer, J. Khan, B. Schäfer, 2020, Modern Pathology.

The S100 family of EF-hand calcium-binding proteins: functions and pathology.

C. Heizmann, B. Schäfer, B W Schäfer, 1996, Trends in biochemical sciences.

Targets for cancer therapy in childhood sarcomas.

B. Schäfer, M. Wachtel, 2010, Cancer treatment reviews.

Prognostic significance of the Ca2+ binding protein S100A2 in laryngeal squamous‐cell carcinoma

C. Heizmann, B. Schäfer, F. Michetti, 2000 .

Helicase CHD 4 is an epigenetic coregulator of PAX 3-FOXO 1 in alveolar rhabdomyosarcoma

B. Schäfer, K. Mamchaoui, P. Nanni, 2019 .

Helicase CHD4 is an epigenetic coregulator of PAX3-FOXO1 in alveolar rhabdomyosarcoma.

B. Schäfer, K. Mamchaoui, P. Nanni, 2016, The Journal of clinical investigation.

Rhabdomyosarcoma: current challenges and their implications for developing therapies.

J. Khan, R. Pal, C. Keller, 2014, Cold Spring Harbor perspectives in medicine.

Systematic analysis of molecular defects in the ferrochelatase gene from patients with erythropoietic protoporphyria.

B. Schäfer, X. Schneider-Yin, J. Deybach, 1998, American journal of human genetics.

PAX3 and PAX7 exhibit conserved cis-acting transcription repression domains and utilize a common gain of function mechanism in alveolar rhabdomyosarcoma

B. Schäfer, F. Barr, J. Bennicelli, 1999, Oncogene.

S100A13. Biochemical characterization and subcellular localization in different cell lines.

C. Heizmann, J. Cox, B. Schäfer, 2000, The Journal of biological chemistry.

BIOCHEMICAL CHARACTERIZATION AND SUBCELLULAR LOCALIZATION IN DIFFERENT CELL LINES*

C. Heizmann, J. Cox, B. Schäfer, 2000 .

Negative correlation of single-cell PAX3:FOXO1 expression with tumorigenicity in rhabdomyosarcoma

M. Boerries, Manching Ku, B. Schäfer, 2021, Life Science Alliance.

Human ferrochelatase: a novel mutation in patients with erythropoietic protoporphyria and an isoform caused by alternative splicing

B. Schäfer, X. Schneider-Yin, E. Minder, 1995, Human Genetics.

Molecular defects in erythropoietic protoporphyria with terminal liver failure

B. Schäfer, G. Burg, X. Schneider-Yin, 1994, Human Genetics.

Recessive inheritance of erythropoietic protoporphyria with liver failure.

B. Schäfer, X. Schneider-Yin, E. Minder, 1994, Lancet.

The Calcium-binding Protein S100A2 Interacts with p53 and Modulates Its Transcriptional Activity*

C. Heizmann, B. Schäfer, S. Ferrari, 2005, Journal of Biological Chemistry.

Targeting hedgehog signaling reduces self-renewal in embryonal rhabdomyosarcoma

B. Schäfer, P. Jaaks, E. Koscielniak, 2015, Oncogene.

Novel FGFR4-Targeting Single-Domain Antibodies for Multiple Targeted Therapies against Rhabdomyosarcoma

B. Schäfer, F. Perez, P. Luciani, 2020, Cancers.

Expression of Ca2+‐binding proteins of the S100 family in malignant human breast‐cancer cell lines and biopsy samples

C. Heizmann, B. Schäfer, U. Eppenberger, 1994, International journal of cancer.

Novel Ca2+-binding S100 Proteins, Glial Fibrillary Acidic Protein and Tenascin in Chondro-osseous Tumors

C. Heizmann, B. Schäfer, Y. Takai, 1997 .

Differential expression of S100 calcium‐binding proteins characterizes distinct clinical entities in both WHO grade II and III astrocytic tumours

C. Heizmann, R. Kiss, B. Schäfer, 2000, Neuropathology and applied neurobiology.

Inhibition of HDACs reduces Ewing sarcoma tumor growth through EWS-FLI1 protein destabilization

B. Schäfer, Q. Ngo, F. Niggli, 2022, Neoplasia.

Gene expression profiles and risk stratification in childhood acute lymphoblastic leukemia

P. Bühlmann, M. Dettling, B. Schäfer, 2004 .

Human α and β parvalbumins

C. Heizmann, B. Schäfer, S. Frutiger, 1993 .

Human alpha and beta parvalbumins. Structure and tissue-specific expression.

C. Heizmann, B. Schäfer, S. Frutiger, 1993, European journal of biochemistry.

S100 Protein Family

C. Heizmann, B. Schäfer, 2002 .

S100A2, a Putative Tumor Suppressor Gene, Regulates In Vitro Squamous Cell Carcinoma Migration

Isabelle Camby, Robert Kiss, Isabelle Salmon, 2001, Laboratory Investigation.

Clustered organization of S100 genes in human and mouse.

C. Heizmann, B. Schäfer, F. Niggli, 1998, Biochimica et biophysica acta.

Altered expression of the Ca(2+)-binding protein S100A1 in human cardiomyopathy.

C. Heizmann, B. Schäfer, P. Erne, 1996, Biochimica et biophysica acta.

Correlation of S100A4 expression with invasion and metastasis in oral squamous cell carcinoma.

C. Heizmann, B. Schäfer, Takuma Sasaki, 2004, Oral oncology.

Development and progression of malignancy in human colon tissues are correlated with expression of specific Ca(2+)-binding S100 proteins.

R. Kiss, B. Schäfer, C. Decaestecker, 2001, Histology and histopathology.

Distribution of a specific calcium‐binding protein of the S100 protein family, S100A6 (calcyclin), in subpopulations of neurons and glial cells of the adult rat nervous system

T. Kosaka, C. Heizmann, B. Schäfer, 1999, The Journal of comparative neurology.

S100 alpha, CAPL, and CACY: molecular cloning and expression analysis of three calcium-binding proteins from human heart.

C. Heizmann, B. Schäfer, P. Erne, 1992, Biochemistry.

Structural insight into human Zn(2+)-bound S100A2 from NMR and homology modeling.

C. Heizmann, B. Schäfer, W. Chazin, 2001, Biochemical and biophysical research communications.

Purification and characterization of the recombinant human calcium-binding S100 proteins CAPL and CACY.

C. Heizmann, J. Cox, B. Schäfer, 1994, Biochemistry.

Paracrine Placental Growth Factor Signaling in Response to Ionizing Radiation Is p53-Dependent and Contributes to Radioresistance

B. Schäfer, M. Pruschy, I. Telarovic, 2021, Molecular Cancer Research.

S 100 A 13 and S 100 A 6 exhibit distinct translocation pathways in endothelial cells

C. Heizmann, J. Cox, B. Schäfer, 2002 .

The First European Interdisciplinary Ewing Sarcoma Research Summit

P. Sorensen, U. Dirksen, O. Delattre, 2012, Front. Oncol..

BAF complexes drive proliferation and block myogenic differentiation in fusion-positive rhabdomyosarcoma

J. Khan, Jun S. Wei, Chaoyu Wang, 2021, Nature Communications.

Multidisciplinary management of childhood sarcoma: time to expand

B. Schäfer, F. Niggli, 2010, Expert review of anticancer therapy.

Effect of cell history on response to helixloophelix family of myogenic regulators

H. Blau, B. Schäfer, G. Darlington, 1990, Nature.

Brain S100A5 Is a Novel Calcium-, Zinc-, and Copper Ion-binding Protein of the EF-hand Superfamily*

C. Heizmann, J. Cox, B. Schäfer, 2000, The Journal of Biological Chemistry.

International Standardization of Minimal Residual Disease Assessment for in Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia (Ph+ALL) Expressing m-BCR-ABL Transcripts: Updated Results of Quality Control Procedures by the EWALL and ESG-MRD-ALL Consortia

E. Yeoh, J. Cayuela, B. Schäfer, 2011 .

Identification of novel DNA binding sites recognized by the transcription factor mPOU (POU6F1).

B. Schäfer, E. Wey, 1996, Biochemical and Biophysical Research Communications - BBRC.

The Proprotein Convertase Furin Contributes to Rhabdomyosarcoma Malignancy by Promoting Vascularization, Migration and Invasion

B. Schäfer, P. Jaaks, M. Bernasconi, 2016, PloS one.

FGFR4 signaling couples to Bim and not Bmf to discriminate subsets of alveolar rhabdomyosarcoma cells

M. Okoniewski, B. Schäfer, F. Niggli, 2014, International journal of cancer.

Genomic and Epigenetic Changes Drive Aberrant Skeletal Muscle Differentiation in Rhabdomyosarcoma

B. Schäfer, J. Shipley, R. Alaggio, 2023, Cancers.

Subtype and prognostic classification of rhabdomyosarcoma by immunohistochemistry.

Silvia Behnke, B. Schäfer, I. Leuschner, 2006, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Ca(2+)-binding proteins S100A6 and S100B in primary cutaneous melanoma.

C. Heizmann, R. Dummer, B. Schäfer, 1997, Journal of cutaneous pathology.

p21 Downregulation is an important component of PAX3/FKHR oncogenicity and its reactivation by HDAC inhibitors enhances combination treatment

B. Schäfer, F. Niggli, D. Walter, 2010, Oncogene.

Phosphorylation regulates transcriptional activity of PAX3/FKHR and reveals novel therapeutic possibilities.

D. Fabbro, B. Schäfer, H. Troxler, 2008, Cancer research.

Localization of the Ca(2+)-binding S100A1 protein in slow and fast skeletal muscles of the rat.

C. Heizmann, B. Schäfer, B. Maco, 1997, General physiology and biophysics.

The second European interdisciplinary Ewing sarcoma research summit – A joint effort to deconstructing the multiple layers of a complex disease

Nathan C. Sheffield, P. Meltzer, P. Sorensen, 2016, Oncotarget.

Transcriptional regulation of S100A1 and expression during mouse heart development.

G. Lyons, C. Heizmann, B. Schäfer, 2000, Biochimica et biophysica acta.

Duxbling Stem Cells Meet Tumorigenesis.

B. Schäfer, 2018, Cell stem cell.

Prospective Evaluation of MRD-Kinetics in 274 Children with High-Risk ALL Treated in Trial ALL-BFM 2000: Insights into Development of Resistance and Impact on Further Refinement of Treatment Stratification Strategies.

B. Schäfer, M. Schrappe, C. Bartram, 2007 .

Furin Targeted Drug Delivery for Treatment of Rhabdomyosarcoma in a Mouse Model

Michele Bernasconi, B. Schäfer, F. Niggli, 2010, PloS one.

The KMT2A recombinome of acute leukemias in 2023

E. Clappier, V. V. D. van der Velden, B. Schäfer, 2023, Leukemia.

Clonal expansion of a new MLL rearrangement in the absence of leukemia.

B. Schäfer, R. Marschalek, L. Trakhtenbrot, 2005, Blood.

Prenatal origin of separate evolution of leukemia in identical twins

M. Dettling, B. Schäfer, D. Betts, 2004, Leukemia.

CHAPTER 138 – The Family of S100 Cell Signaling Proteins

C. Heizmann, B. Schäfer, G. Fritz, 2003 .

Cell-Based Small-Molecule Compound Screen Identifies Fenretinide as Potential Therapeutic for Translocation-Positive Rhabdomyosarcoma

B. Schäfer, Aleksandar Boro, David Herrero Martín, 2013, PloS one.

Fenretinide induces a new form of dynamin-dependent cell death in pediatric sarcoma

B. Schäfer, A. Kaech, U. Ziegler, 2020, Cell Death & Differentiation.

Fenretinide Acts as Potent Radiosensitizer for Treatment of Rhabdomyosarcoma Cells

B. Schäfer, M. Pruschy, S. Bender, 2021, Frontiers in Oncology.

USP19 deubiquitinates EWS-FLI1 to regulate Ewing sarcoma growth

B. Schäfer, P. Jaaks, Laura A. Lopez-Garcia, 2019, Scientific Reports.

The calcium-binding protein S 100 A 2 interacts with p 53 and modulates its transcriptional activity

C. Heizmann, B. Schäfer, S. Ferrari, 2017 .

The MLL recombinome of acute leukemias in 2013

W. Choi, S. Bohlander, E. Clappier, 2013, Leukemia.

Clinical significance of S100A4 and E-cadherin-related adhesion molecules in non-small cell lung cancer.

C. Heizmann, B. Schäfer, B. Schafer, 2000, International journal of oncology.

Localization of Ca2+-binding S100 proteins in epithelial tumours of the skin

C. Heizmann, B. Schäfer, Y. Takai, 1998, Virchows Archiv.

Molecular cloning and characterization of a human PAX-7 cDNA expressed in normal and neoplastic myocytes.

B. Schäfer, M. Busslinger, T. Czerny, 1994, Nucleic acids research.

Preferred analysis methods for single genomic regions in RNA sequencing revealed by processing the shape of coverage

Alicja Szabelska, Ralph Schlapbach, Anna Leśniewska, 2011, Nucleic acids research.

Alpha-parvalbumin reduces depolarization-induced elevations of cytosolic free calcium in human neuroblastoma cells.

C. Heizmann, B. Schäfer, T. Knöpfel, 1996, Cell Calcium.

Unpeaceful roles of mutant PAX proteins in cancer.

B. Schäfer, M. Wachtel, Marco Wachtel, 2015, Seminars in Cell and Developmental Biology.

PLK1 phosphorylates PAX3-FOXO1, the inhibition of which triggers regression of alveolar Rhabdomyosarcoma.

B. Schäfer, D. Herrero-Martín, E. Koscielniak, 2015, Cancer Research.

Targets for cancer therapy in childhood sarcomas.

B. Schäfer, Marco Wachtel, 2010, Cancer treatment reviews.

Cloning and Characterization of the Human PAX7 Promoter

B. Schäfer, F. Niggli, Omar V. Murmann, 2000, Biological chemistry.

Single cell transcriptomic profiling identifies tumor-acquired and therapy-resistant cell states in pediatric rhabdomyosarcoma

B. Schäfer, Elizabeth Stewart, D. Langenau, 2023, bioRxiv.

Late MRD response determines relapse risk overall and in subsets of childhood T-cell ALL: results of the AIEOP-BFM-ALL 2000 study.

J. V. van Dongen, B. Schäfer, M. Schrappe, 2011, Blood.

PAX3-FOXO1 uses its activation domain to recruit CBP/P300 and shape RNA Pol2 cluster distribution

Richard C. Sallari, B. Schäfer, Q. Ngo, 2023, Nature communications.

Rapid Molecular Diagnosis of Erythropoietic Protoporphyria among Swiss Patients

B. Schäfer, X. Schneider-Yin, J. Deybach, 1998, Clinical chemistry and laboratory medicine.