P. Borrow

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Association of strong virus-specific CD4 T cell responses with efficient natural control of primary HIV-1 infection

D. Cornforth, I. Williams, J. Lifson, 2004, AIDS.

Determinants of Human Immunodeficiency Virus Type 1 Escape from the Primary CD8+ Cytotoxic T Lymphocyte Response

M. Nowak, D. Flower, G. Shaw, 2004, The Journal of experimental medicine.

Broad and strong memory CD4+ and CD8+ T cells induced by SARS-CoV-2 in UK convalescent individuals following COVID-19

P. Sopp, D. Stuart, P. Klenerman, 2020, Nature Immunology.

Infection of lymphocytes by a virus that aborts cytotoxic T lymphocyte activity and establishes persistent infection

P. Borrow, M. Oldstone, A. Tishon, 1991, The Journal of experimental medicine.

Kinetics of Expansion of Epitope-Specific T Cell Responses during Primary HIV-1 Infection1

Xiping Wei, Persephone Borrow, Brandon F. Keele, 2009, The Journal of Immunology.

The first T cell response to transmitted/founder virus contributes to the control of acute viremia in HIV-1 infection

Alan S. Perelson, Tanmoy Bhattacharya, Guido Ferrari, 2009, The Journal of experimental medicine.

Coupling In Silico and In Vitro Analysis of Peptide-MHC Binding: A Bioinformatic Approach Enabling Prediction of Superbinding Peptides and Anchorless Epitopes

Darren R Flower, Persephone Borrow, Irini A Doytchinova, 2004, The Journal of Immunology.

A trip down memory lane with Retrovirology

B. Berkhout, P. Borrow, F. Kirchhoff, 2019, Retrovirology.

HIV-1 gp41 envelope IgA is frequently elicited after transmission but has an initial short response half-life

W. Blattner, B. Haynes, D. Montefiori, 2013, Mucosal Immunology.

Discrimination Between Human Leukocyte Antigen Class I-Bound and Co-Purified HIV-Derived Peptides in Immunopeptidomics Workflows

P. Borrow, Anna E. Kliszczak, B. Kessler, 2018, Front. Immunol..

Chapter 22 Virus-induced alterations in cells

P. Borrow, J. C. D. L. Torre, 1998 .

Measles virus-mononuclear cell interactions.

P. Borrow, M. Oldstone, 1995, Current topics in microbiology and immunology.

Innate immune responses in primary HIV-1 infection

P. Borrow, N. Bhardwaj, 2008, Current opinion in HIV and AIDS.

SAP controls T cell responses to virus and terminal differentiation of TH2 cells

P. Borrow, A. Sharpe, A. Satoskar, 2001, Nature Immunology.

Activation of CCR2+ human proinflammatory monocytes by human herpesvirus-6B chemokine N-terminal peptide.

P. Borrow, U. Gompels, J. Catusse, 2013, The Journal of general virology.

Hybrid Spreading Mechanisms and T Cell Activation Shape the Dynamics of HIV-1 Infection

Ian Williams, Shi Zhou, Persephone Borrow, 2015, PLoS Comput. Biol..

Broad and strong memory CD4+ and CD8+ T cells induced by SARS-CoV-2 in UK convalescent COVID-19 patients

P. Sopp, D. Stuart, P. Klenerman, 2020, bioRxiv.

Innate immunity in acute HIV-1 infection.

P. Borrow, 2011, Current opinion in HIV and AIDS.

Blocking of feline immunodeficiency virus infection by a monoclonal antibody to CD9 is via inhibition of virus release rather than interference with receptor binding

P. Borrow, D. L. Lerner, B. Willett, 1997, Journal of virology.

Replication of lymphocytic choriomeningitis virus is restricted in terminally differentiated neurons

P. Borrow, P. Sanna, L. De, 1993, Journal of virology.

Contribution of proteasome-catalyzed peptide cis-splicing to viral targeting by CD8+ T cells in HIV-1 infection

G. Learn, B. Haynes, I. Williams, 2019, Proceedings of the National Academy of Sciences.

Multiple Mechanisms Contribute to Impairment of Type 1 Interferon Production during Chronic Lymphocytic Choriomeningitis Virus Infection of Mice1

P. Borrow, L. Lee, Shannon Burke, 2009, The Journal of Immunology.

Expression of the β‐glucan receptor, Dectin‐1, on murine leukocytes in situ correlates with its function in pathogen recognition and reveals potential roles in leukocyte interactions

S. Gordon, P. Taylor, P. Borrow, 2004, Journal of leukocyte biology.

HIV-1 infection – induced apoptotic microparticles inhibit human DCs via CD 44

B. Haynes, P. Borrow, S. Khan, 2012 .

HIV-1 infection-induced apoptotic microparticles inhibit human DCs via CD44.

B. Haynes, P. Borrow, S. Khan, 2012, The Journal of clinical investigation.

Completeness of HIV-1 Envelope Glycan Shield at Transmission Determines Neutralization Breadth

Bette Korber, Gwo-Yu Chuang, Peter D. Kwong, 2018, Cell reports.

CD4+ T Follicular Helper Cells in Human Tonsils and Blood Are Clonally Convergent but Divergent from Non-Tfh CD4+ Cells

A. N. Davydov, A. McMichael, P. Borrow, 2020, Cell reports.

Dynamics of Transforming Growth Factor (TGF)-β Superfamily Cytokine Induction During HIV-1 Infection Are Distinct From Other Innate Cytokines

I. Williams, P. Borrow, E. Giannoulatou, 2020, Frontiers in Immunology.

Noncytopathic Clearance of Lymphocytic Choriomeningitis Virus from the Hepatocyte

F. Chisari, P. Borrow, L. Guidotti, 1999, The Journal of experimental medicine.

Discriminated selection among viral peptides with the appropriate anchor residues: implications for the size of the cytotoxic T-lymphocyte repertoire and control of viral infection

P. Borrow, H. Lewicki, M. Oldstone, 1995, Journal of virology.

Impact of Micropolymorphism Outside the Peptide Binding Groove in the Clinically Relevant Allele HLA-C*14 on T Cell Responses in HIV-1 Infection

P. Borrow, S. Oka, Wayne Paes, 2022, Journal of virology.

Virus-induced immunosuppression: kinetic analysis of the selection of a mutation associated with viral persistence

P. Borrow, J. C. de la Torre, M. Oldstone, 1994, Journal of virology.

Replication ofLymphocytic Choriomeningitis VirusIs Restricted inTerminally Differentiated Neuronst

P. Borrow, P. Sanna, G. Rall, 1993 .

Characterization of lymphocytic choriomeningitis virus-binding protein(s): a candidate cellular receptor for the virus

P. Borrow, M. Oldstone, 1992, Journal of virology.

Virus infection‐associated bone marrow B cell depletion and impairment of humoral immunity to heterologous infection mediated by TNF‐α/LTα

S. Gloster, P. Borrow, L. Hyland, 2005, European journal of immunology.

Circulating inflammatory biomarkers can predict and characterize tuberculosis-associated immune reconstitution inflammatory syndrome

L. Haddow, P. Easterbrook, P. Borrow, 2011, AIDS.

HIV-1 Promotes the Degradation of Components of the Type 1 IFN JAK/STAT Pathway and Blocks Anti-viral ISG Induction

P. Borrow, N. Stevenson, C. O’Farrelly, 2018, EBioMedicine.

interference with receptor binding. via inhibition of virus release rather than infection by a monoclonal antibody to CD9 is Blocking of feline immunodeficiency virus

P. Borrow, D. L. Lerner, B. Willett, 2013 .

Immunization-induced inflammatory infiltration of the central nervous system in transgenic mice expressing a microbial antigen in astrocytes

L. Mucke, P. Borrow, M. Ruppe, 1995, Journal of Neuroimmunology.

Mechanisms of viral clearance and persistence

P. Borrow, 1997, Journal of viral hepatitis.

Cell‐surface bound pertussis toxin induces polyclonal T cell responses with high levels of interferon‐γ in the absence of interleukin‐12

P. Borrow, P. Beverley, K. Rigley, 2003, European journal of immunology.

Biomagnetic isolation of antigen-specific CD8+ T cells usable in immunotherapy

M. Jackson, P. A. Peterson, P. Borrow, 1998, Nature Biotechnology.

Defective B cell responses in the absence of SH2D1A.

W. Leonard, P. Borrow, A. Satoskar, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Viruses transfer the antiviral second messenger cGAMP between cells

P. Borrow, Alice Mayer, J. Rehwinkel, 2015, Science.

Polyinosinic Acid Is a Ligand for Toll-like Receptor 3*

P. Borrow, I. Haga, A. Bowie, 2007, Journal of Biological Chemistry.

Molecular Basis ofViral Persistence: a Single AminoAcidChange intheGlycoprotein ofLymphocytic Choriomeningitis VirusIs Associated withSuppression oftheAntiviral Cytotoxic T- Lymphocyte Response andEstablishment ofPersistencet

P. Borrow, M. Salvato, E. Shimomaye, 1991 .

Functional Characterization of Intracellular and Secreted Forms of a Truncated Hepatitis C Virus E2 Glycoprotein

P. Borrow, J. Dubuisson, J. McKeating, 2000, Journal of Virology.

Germinal Center B Cell and T Follicular Helper Cell Responses to Viral Vector and Protein-in-Adjuvant Vaccines

P. Borrow, S. Draper, A. D. Douglas, 2016, The Journal of Immunology.

Evidence of dysregulation of dendritic cells in primary HIV infection

K. Shianna, J. Fellay, M. Markowitz, 2010, Blood.

Antisense-Derived HIV-1 Cryptic Epitopes Are Not Major Drivers of Viral Evolution during the Acute Phase of Infection

A. McMichael, P. Borrow, J. Carlson, 2018, Journal of Virology.

HIV-1 Infection Functional Flexibility in HIV-2 Compared to TCR Heterogeneity and + Greater CD8

H. Whittle, I. Williams, P. Borrow, 2003 .

Epitopes Superbinding Peptides and Anchorless Approach Enabling Prediction of Peptide-MHC Binding : A Bioinformatic Coupling In Silico and In Vitro Analysis of Flower

I. Doytchinova, S. Gloster, P. Borrow, 2004 .

Mechanism of lymphocytic choriomeningitis virus entry into cells.

P. Borrow, M. Oldstone, 1994, Virology.

Elucidation of the Signatures of Proteasome-Catalyzed Peptide Splicing

P. Borrow, Wayne Paes, N. Ternette, 2020, Frontiers in Immunology.

Elucidation of the signatures of proteasome-catalysed peptide splicing

P. Borrow, Wayne Paes, N. Ternette, 2020, bioRxiv.

CTL escape viral variants. I. Generation and molecular characterization.

K. Hahn, D. Jewell, I. Wilson, 1995, Virology.

CD45 is required for type I IFN production by dendritic cells

P. Borrow, E. Tchilian, P. Beverley, 2006, European journal of immunology.

Study of the mechanisms by which CD4+ T cells contribute to protection in Theiler's murine encephalomyelitis.

P. Borrow, A. Nash, C. Welsh, 1993, Immunology.

Asymptomatic Primary Infection with Epstein-Barr Virus: Observations on Young Adult Cases

P. Borrow, P. Moss, A. Rickinson, 2017, Journal of Virology.

Deletion of the deISGylating enzyme USP 18 enhances 1 tumour cell antigenicity and radiosensitivity 2 3

A. Damianou, P. Borrow, V. Cerundolo, 2020 .

IL-15 re-programming compensates for NK cell mitochondrial dysfunction in HIV-1 infection

S. Rowland-Jones, P. Borrow, Michael Loran Dustin, 2019 .

Influenza H2 haemagglutinin activates B cells via a MyD88‐dependent pathway

P. Borrow, S. Wharton, David Wiseman, 2006, European journal of immunology.

Lymphocytic Choriomeningitis Virus (LCMV)

P. Borrow, 2003 .

Reciprocal Immunomodulation in a Schistosome and Hepatotropic Virus Coinfection Model1

P. Borrow, Q. Bickle, M. Edwards, 2005, The Journal of Immunology.

Altered CD45 isoform expression affects lymphocyte function in CD45 Tg mice.

P. Borrow, D. Tough, L. Hyland, 2004, International immunology.

Altered CD 45 isoform expression affects lymphocyte function in CD 45 Tg mice

P. Borrow, D. Tough, L. Hyland, 2004 .

Mapping the epitopes of the Human Leukocyte Antigen E antibodies 3D12 and 4D12

A. McMichael, P. Borrow, S. Brackenridge, 2022, bioRxiv.

RAB11FIP5-Deficient Mice Exhibit Cytokine-Related Transcriptomic Signatures

B. Haynes, P. Borrow, S. Xia, 2020, ImmunoHorizons.

Transcriptomic Signatures -Deficient Mice Exhibit Cytokine-Related RAB11FIP5

B. Haynes, P. Borrow, S. Xia, 2020 .

A role for the transcription factor RelB in IFN‐α production and in IFN‐α‐stimulated cross‐priming

P. Borrow, D. Lo, D. Tough, 2006 .

Rapid Activation of Spleen Dendritic Cell Subsets following Lymphocytic Choriomeningitis Virus Infection of Mice: Analysis of the Involvement of Type 1 IFN1

P. Borrow, Delyth M. Reid, M. Edwards, 2005, The Journal of Immunology.

Analysis of the Involvement of Type 1 IFN Choriomeningitis Virus Infection of Mice: Subsets following Lymphocytic Rapid Activation of Spleen Dendritic Cell

P. Borrow, Delyth M. Reid, M. Edwards, 2005 .

Virus-induced immunosuppression. 1. Age at infection relates to a selective or generalized defect.

P. Borrow, M. Oldstone, A. Tishon, 1993, Virology.

Viral persistence and disease: cytopathology in the absence of cytolysis.

P. Borrow, J. C. de la Torre, M. Oldstone, 1991, British medical bulletin.

Theiler's virus: an experimental model of virus-induced demyelination.

P. Borrow, A. Nash, C. Welsh, 1990, Autoimmunity.

Circadian regulation of human immunodeficiency virus type 1 replication

P. Borrow, J. McKeating, Anna E. Kliszczak, 2022, bioRxiv.

REGULATION OF THE CELL SURFACE EXPRESSION OF CLASSICAL AND NON- 1 CLASSICAL MHC PROTEINS BY THE HUMAN CYTOMEGALOVIRUS UL40 AND 2 RHESUS CYTOMEGALOVIRUS RH67 PROTEINS

P. Borrow, S. Brackenridge, A. McMichael, 2022 .

Major expansion of CD8+ T cells with a predominant Vβ usage during the primary immune response to HIV

Persephone Borrow, Anthony S. Fauci, Michael S. Saag, 1994, Nature.

Interleukin-10 responses to therapeutic vaccination during highly active antiretroviral therapy and after analytical therapy interruption

A. McMichael, P. Borrow, M. Davenport, 2009, AIDS.

Deep analysis of the USP18-dependent ISGylome and proteome unveils important roles for USP18 in tumour cell antigenicity and radiosensitivity

Andreas C. Damianou, A. Damianou, P. Borrow, 2020, bioRxiv.

Susceptibility to Theiler's virus-induced demyelinating disease correlates with astrocyte class II induction and antigen presentation.

P. Borrow, A. Nash, 1992, Immunology.

Evaluation of the effects of human leukocyte IFN-alpha on the immune response to the HBV vaccine in healthy unvaccinated individuals.

P. Borrow, C. Castilletti, M. Capobianchi, 2008, Vaccine.

Galectin-9 is rapidly released during acute HIV-1 infection and remains sustained at high levels despite viral suppression even in elite controllers.

Marion C Lanteri, Jeffrey N. Martin, P. Borrow, 2014, AIDS research and human retroviruses.

Phenotypic properties of transmitted founder HIV-1

Feng Gao, Bette Korber, Hui Li, 2013, Proceedings of the National Academy of Sciences.

Induction of a Striking Systemic Cytokine Cascade prior to Peak Viremia in Acute Human Immunodeficiency Virus Type 1 Infection, in Contrast to More Modest and Delayed Responses in Acute Hepatitis B and C Virus Infections

Mila Lebedeva, John Heitman, Persephone Borrow, 2009, Journal of Virology.

Distinct patterns of hepcidin and iron regulation during HIV-1, HBV, and HCV infections

P. J. Norris, A. Prentice, I. Williams, 2014, Proceedings of the National Academy of Sciences.

Induction of a strong HIV-specific CD8+ T cell response in mice using a fowlpox virus vector expressing an HIV-1 multi-CTL-epitope polypeptide.

P. Borrow, M. Skinner, S. Laidlaw, 2002, Viral immunology.

Viral infection switches non-plasmacytoid dendritic cells into high interferon producers

Persephone Borrow, Hermann Unger, Lena Alexopoulou, 2003, Nature.

Cytokines induced during chronic hepatitis B virus infection promote a pathway for NK cell–mediated liver damage

P. Borrow, Kevin T. Williams, G. Reynolds, 2007, The Journal of experimental medicine.

Receptor structure, binding, and cell entry of arenaviruses.

P. Borrow, S. Kunz, M. Oldstone, 2002, Current topics in microbiology and immunology.

Evolutionary dynamics of hepatitis C virus envelope genes during chronic infection.

Shelley L. Hemsley, D. Flower, P. Borrow, 2005, The Journal of general virology.

HIV-1 Populations in Semen Arise through Multiple Mechanisms

Cassandra B. Jabara, Corbin D. Jones, P. Borrow, 2010, PLoS pathogens.

Viral cross talk: intracellular inactivation of the hepatitis B virus during an unrelated viral infection of the liver.

F. Chisari, P. Borrow, I. Gresser, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Reappraisal of the Relationship between the HIV-1-Protective Single-Nucleotide Polymorphism 35 Kilobases Upstream of the HLA-C Gene and Surface HLA-C Expression

A. McMichael, P. Borrow, S. Brackenridge, 2011, Journal of Virology.

Origin and Evolution of HIV-1 in Breast Milk Determined by Single-Genome Amplification and Sequencing

G. Learn, D. Montefiori, S. Meshnick, 2010, Journal of Virology.

Inhibition of the Type I Interferon Antiviral Response During Arenavirus Infection

P. Borrow, J. C. de la Torre, L. Martínez-Sobrido, 2010, Viruses.

Aberrant B cell repertoire selection associated with HIV neutralizing antibody breadth

K. Roskin, H. Liao, B. Haynes, 2020, Nature Immunology.

Differences in Affinity of Binding of Lymphocytic Choriomeningitis Virus Strains to the Cellular Receptor α-Dystroglycan Correlate with Viral Tropism and Disease Kinetics

K. Campbell, P. Borrow, S. Kunz, 2001, Journal of Virology.

Virus-induced immunosuppression: immune system-mediated destruction of virus-infected dendritic cells results in generalized immune suppression

P. Borrow, M. Oldstone, C. Evans, 1995, Journal of virology.

Pathogen-derived HLA-E bound epitopes reveal broad primary anchor pocket tolerability and conformationally malleable peptide binding

L. Picker, A. McMichael, P. Borrow, 2018, Nature Communications.

Mouse and human antibodies bind HLA-E-leader peptide complexes and enhance NK cell cytotoxicity

B. Haynes, A. McMichael, P. Borrow, 2020, Communications Biology.

Type I interferons produced by dendritic cells promote their phenotypic and functional activation.

Ion Gresser, Persephone Borrow, Filippo Belardelli, 2002, Blood.

Defining the HLA class I‐associated viral antigen repertoire from HIV‐1‐infected human cells

M. Nielsen, C. Brander, P. Borrow, 2015, European journal of immunology.

Magnitude and Quality of Cytokine and Chemokine Storm during Acute Infection Distinguish Nonprogressive and Progressive Simian Immunodeficiency Virus Infections of Nonhuman Primates

Norman L. Letvin, Persephone Borrow, Nicola Ternette, 2016, Journal of Virology.

Induction of Bystander T Cell Proliferation by Viruses and Type I Interferon in Vivo

J. Sprent, P. Borrow, D. Tough, 1996, Science.

Deletion of the deISGylating enzyme USP18 enhances tumour cell antigenicity and radiosensitivity

Andreas C. Damianou, A. Damianou, P. Borrow, 2020, British Journal of Cancer.

Innate immunity against HIV: a priority target for HIV prevention research

P. Borrow, R. Shattock, A. Vyakarnam, 2010, Retrovirology.

HLA variants have different preferences to present proteins with specific molecular functions which are complemented in frequent haplotypes

Isaac B. Woodhouse, P. Borrow, D. Chudakov, 2022, Frontiers in Immunology.

HLA binding of self-peptides is biased towards proteins with specific molecular functions

Isaac B. Woodhouse, P. Borrow, D. Chudakov, 2021, bioRxiv.

Prevalence of antibodies to Epstein-Barr virus nuclear antigen 2B in persons infected with the human immunodeficiency virus.

D. Cooper, P. Borrow, T. Sculley, 1988, The Journal of infectious diseases.

HLA-E–restricted, Gag-specific CD8+ T cells can suppress HIV-1 infection, offering vaccine opportunities

L. Picker, A. McMichael, P. Borrow, 2021, Science Immunology.

cGAMP loading enhances the immunogenicity of VLP vaccines

P. Borrow, J. Rehwinkel, A. Townsend, 2020, bioRxiv.

Protein/AS01B vaccination elicits stronger, more Th2-skewed antigen-specific human T follicular helper cell responses than heterologous viral vectors

B. Haynes, P. Borrow, Yue Chen, 2021, Cell reports. Medicine.

The role of CD8+T cells in the acute and chronic phases of Theiler's murine encephalomyelitis virus-induced disease in mice.

P. Borrow, A. Nash, C. Welsh, 1992, The Journal of general virology.

Aberrant B cell repertoire selection associated with HIV neutralizing antibody breadth

K. Roskin, H. Liao, B. Haynes, 2020, Nature Immunology.

Identification of alpha-dystroglycan as a receptor for lymphocytic choriomeningitis virus and Lassa fever virus.

K. Campbell, P. Borrow, R. Compans, 1998, Science.

Relative resistance of HIV-1 founder viruses to control by interferon-alpha

H. Ding, J. Kappes, I. Williams, 2013, Retrovirology.

Vertical T cell immunodominance and epitope entropy determine HIV-1 escape.

Feng Gao, Hui Li, Guido Ferrari, 2012, The Journal of clinical investigation.

Fitness Costs and Diversity of the Cytotoxic T Lymphocyte (CTL) Response Determine the Rate of CTL Escape during Acute and Chronic Phases of HIV Infection

Alan S. Perelson, Guido Ferrari, Vitaly V. Ganusov, 2011, Journal of Virology.

Relationship between Functional Profile of HIV-1 Specific CD8 T Cells and Epitope Variability with the Selection of Escape Mutants in Acute HIV-1 Infection

Mario Roederer, Bette Korber, Guido Ferrari, 2011, PLoS pathogens.

The immune response during acute HIV-1 infection: clues for vaccine development

Persephone Borrow, Andrew J. McMichael, Barton F. Haynes, 2009, Nature Reviews Immunology.

Transmitted Virus Fitness and Host T Cell Responses Collectively Define Divergent Infection Outcomes in Two HIV-1 Recipients

Jessica L. Prince, A. Perelson, G. Shaw, 2015, PLoS pathogens.

Antiviral pressure exerted by HIV-l-specific cytotoxic T lymphocytes (CTLs) during primary infection demonstrated by rapid selection of CTL escape virus

Xiping Wei, Persephone Borrow, George M. Shaw, 1997, Nature Medicine.

Detection of Antibody-Dependent Complement-Mediated Inactivation of both Autologous and Heterologous Virus in Primary Human Immunodeficiency Virus Type 1 Infection

D. Cornforth, I. Williams, P. Newton, 2005, Journal of Virology.

Development of the antibody response in acute HIV-1 infection

David Cornforth, Persephone Borrow, Peter Balfe, 2004, AIDS.

Cytotoxic T‐lymphocyte escape viral variants: how important are they in viral evasion of immune clearance in vivo?

G. Shaw, P. Borrow, 1998, Immunological reviews.

A single amino acid change in the glycoprotein of lymphocytic choriomeningitis virus is associated with the ability to cause growth hormone deficiency syndrome

P. Borrow, J. C. de la Torre, M. Oldstone, 1996, Journal of virology.

Virus-specific CD8+ cytotoxic T-lymphocyte activity associated with control of viremia in primary human immunodeficiency virus type 1 infection

G. Shaw, P. Borrow, B. Hahn, 1994, Journal of virology.

Molecular basis of viral persistence: a single amino acid change in the glycoprotein of lymphocytic choriomeningitis virus is associated with suppression of the antiviral cytotoxic T-lymphocyte response and establishment of persistence

P. Borrow, M. Oldstone, M. Salvato, 1991, Journal of virology.

Cross-priming of CD8+ T cells stimulated by virus-induced type I interferon

P. Borrow, D. Tough, D. Gewert, 2003, Nature Immunology.

Copy Number Variation of KIR Genes Influences HIV-1 Control

K. Shianna, D. Ge, A. Need, 2011, PLoS biology.

HIV-1 Epitope-Specific CD8+ T Cell Responses Strongly Associated with Delayed Disease Progression Cross-Recognize Epitope Variants Efficiently1

D. Cornforth, I. Williams, P. Borrow, 2006, The Journal of Immunology.

Mapping the SARS-CoV-2 spike glycoprotein-derived peptidome presented by HLA class II on dendritic cells

B. Haynes, P. Borrow, P. Acharya, 2021, Cell Reports.

Variants Efficiently Disease Progression Cross-Recognize Epitope Responses Strongly Associated with Delayed T Cell + HIV-1 Epitope-Specific CD 8

D. Cornforth, I. Williams, P. Borrow, 2006 .

Integrating In Silico and In Vitro Analysis of Peptide Binding Affinity to HLA-Cw*0102: A Bioinformatic Approach to the Prediction of New Epitopes

Channa K. Hattotuwagama, Irini A. Doytchinova, Darren R. Flower, 2009, PloS one.

A Stronger Innate Immune Response During Hyperacute Human Immunodeficiency Virus Type 1 (HIV-1) Infection Is Associated With Acute Retroviral Syndrome

T. Ndung’u, S. Rowland-Jones, A. Kamali, 2021, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Hypoxic microenvironment shapes HIV-1 replication and latency

P. Borrow, M. Ashcroft, J. McKeating, 2020, Communications Biology.

Adaptive Reconfiguration of Natural Killer Cells in HIV-1 Infection

I. Williams, P. Borrow, M. Maini, 2018, Front. Immunol..

Distinct Kinetics of Gag-Specific CD4+ and CD8+ T Cell Responses during Acute HIV-1 Infection

B. Haynes, C. Gray, A. McMichael, 2012, Journal of Immunology.

Infection T Cell Responses during Acute HIV-1 + CD 8 and + Distinct Kinetics of Gag-Specific CD 4 and

B. Haynes, A. McMichael, M. Betts, 2012 .

Elevation of Intact and Proteolytic Fragments of Acute Phase Proteins Constitutes the Earliest Systemic Antiviral Response in HIV-1 Infection

B. Haynes, A. McMichael, P. Borrow, 2010, PLoS pathogens.

The promise and challenge of anti-HIV cellular immunity

P. Borrow, E. Turnbull, 2006, Current opinion in HIV and AIDS.

Transmission of Single HIV-1 Genomes and Dynamics of Early Immune Escape Revealed by Ultra-Deep Sequencing

Alan S. Perelson, Timothy C. Wallstrom, Tanmoy Bhattacharya, 2010, PloS one.

Heightened resistance to host type 1 interferons characterizes HIV-1 at transmission and after antiretroviral therapy interruption

R. Siliciano, P. Sharp, M. Nussenzweig, 2021, Science Translational Medicine.

Heightened resistance to type 1 interferons characterizes HIV-1 at transmission and following treatment interruption

P. Borrow, A. Fenton-May, 2020 .

Heightened resistance to type 1 interferons characterizes HIV-1 at transmission and following analytical treatment interruption

R. Siliciano, P. Sharp, M. Nussenzweig, 2020 .

HIV-Host Interactions: Implications for Vaccine Design.

B. Korber, J. Sodroski, B. Haynes, 2016, Cell host & microbe.

Escape is a more common mechanism than avidity reduction for evasion of CD8+ T cell responses in primary human immunodeficiency virus type 1 infection

I. Williams, G. Shaw, P. Borrow, 2011, Retrovirology.

Multisite Comparison of High-Sensitivity Multiplex Cytokine Assays

J. Margolick, P. Borrow, C. Rinaldo, 2011, Clinical and Vaccine Immunology.

A multi-site comparison of high-sensitivity multiplex cytokine assays 1 Running Title : Multi-site comparison of multiplex cytokine assays 2 3

J. Margolick, P. Borrow, C. Rinaldo, 2011 .

Sexually transmitted founder HIV-1 viruses are relatively resistant to Langerhans cell-mediated restriction

J. Kappes, P. Borrow, B. Hahn, 2019, PloS one.

Resistance to type 1 interferons is a major determinant of HIV-1 transmission fitness

G. Learn, B. Haynes, P. Sharp, 2017, Proceedings of the National Academy of Sciences.

Viral Escape from Neutralizing Antibodies in Early Subtype A HIV-1 Infection Drives an Increase in Autologous Neutralization Breadth

Anurag Sethi, S. Gnanakaran, Persephone Borrow, 2013, PLoS pathogens.

Hepatitis C Virus Envelope Glycoprotein Fitness Defines Virus Population Composition following Transmission to a New Host

S. Réhman, P. Borrow, A. Tarr, 2012, Journal of Virology.

New Host Composition following Transmission to a Fitness Defines Virus Population Hepatitis C Virus Envelope Glycoprotein

P. Borrow, A. Tarr, J. Ball, 2012 .

Cross-Sectional Detection of Acute HIV Infection: Timing of Transmission, Inflammation and Antiretroviral Therapy

Guido Ferrari, Hui Li, David Margolis, 2011, PloS one.

Broad TCR Usage in Functional HIV-1-Specific CD8+ T Cell Expansions Driven by Vaccination during Highly Active Antiretroviral Therapy1

A. McMichael, P. Borrow, P. Bowness, 2007, The Journal of Immunology.

The immune response to human immunodeficiency virus type 1 (HIV-1)

P. Borrow, E. Turnbull, 2005 .

Greater CD8+ TCR Heterogeneity and Functional Flexibility in HIV-2 Compared to HIV-1 Infection1

Darren R. Flower, Persephone Borrow, Lucy Dorrell, 2003, The Journal of Immunology.

Mapping the SARS-CoV-2 spike glycoprotein-derived peptidome presented by HLA class II on dendritic cells

B. Haynes, P. Borrow, P. Acharya, 2020, bioRxiv.

Immunologic characteristics of HIV‐infected individuals who make broadly neutralizing antibodies

P. Borrow, M. A. Moody, 2017, Immunological reviews.

Heterosexual Transmission of Subtype C HIV-1 Selects Consensus-Like Variants without Increased Replicative Capacity or Interferon-α Resistance

Martin J. Deymier, P. Borrow, S. Allen, 2015, PLoS pathogens.

Differential Immunodominance Hierarchy of CD8+ T-Cell Responses in HLA-B*27:05- and -B*27:02-Mediated Control of HIV-1 Infection

M. Carrington, B. Walker, M. John, 2017, Journal of Virology.

Differential Immunodominance Hierarchy of CD8+ T-Cell Responses in HLA-B*27:05- and -B*27:02-Mediated Control of HIV-1 Infection

M. Carrington, B. Walker, M. John, 2017, Journal of Virology.

Monsef Benkirane awarded 2013 Ming K. Jeang Foundation Retrovirology Prize: Landmark HIV-1 research honoured

B. Berkhout, M. Wainberg, P. Borrow, 2013, Retrovirology.

Resistance of Transmitted Founder HIV-1 to IFITM-Mediated Restriction

P. Borrow, B. Hahn, P. Kellam, 2016, Cell host & microbe.

Subordinate Effect of -21M HLA-B Dimorphism on NK Cell Repertoire Diversity and Function in HIV-1 Infected Individuals of African Origin

B. Haynes, P. Borrow, D. Peppa, 2020, Frontiers in Immunology.

Subordinate effect of −21M HLA-B dimorphism on NK cell repertoire diversity and function in HIV-1 infected individuals of African origin

B. Haynes, P. Borrow, D. Peppa, 2019, bioRxiv.

RAB11FIP5 Expression and Altered Natural Killer Cell Function Are Associated with Induction of HIV Broadly Neutralizing Antibody Responses

Ricardo Henao, C. Woods, G. Ginsburg, 2018, Cell.

Investigation of the role of delayed-type-hypersensitivity responses to myelin in the pathogenesis of Theiler's virus-induced demyelinating disease.

P. Borrow, W. Blakemore, A. Nash, 1998, Immunology.

CD40 Ligand-Mediated Interactions Are Involved in the Generation of Memory CD8+ Cytotoxic T Lymphocytes (CTL) but Are Not Required for the Maintenance of CTL Memory following Virus Infection

J. Sprent, P. Borrow, R. Flavell, 1998, Journal of Virology.

The CD40-CD154 system in anti-infective host defense.

P. Borrow, E. Pamer, R. Flavell, 1997, Current opinion in immunology.

CD40L-deficient mice show deficits in antiviral immunity and have an impaired memory CD8+ CTL response

P. Borrow, R. Flavell, M. Oldstone, 1996, The Journal of experimental medicine.

Initial T cell frequency dictates memory CD8+ T cell lineage commitment

Leo Lefrançois, Persephone Borrow, P. Borrow, 2005, Nature Immunology.

Identification of Immunodominant HIV-1 Epitopes Presented by HLA-C*12:02, a Protective Allele, Using an Immunopeptidomics Approach

P. Borrow, S. Oka, Wayne Paes, 2019, Journal of Virology.

Shared Alterations in NK Cell Frequency, Phenotype, and Function in Chronic Human Immunodeficiency Virus and Hepatitis C Virus Infections

Rachel E. Owen, P. Klenerman, I. Williams, 2005, Journal of Virology.

Inclusion of cGAMP within virus‐like particle vaccines enhances their immunogenicity

P. Borrow, J. Rehwinkel, R. Russell, 2021, EMBO reports.

Strategies for HIV-1 vaccines that induce broadly neutralizing antibodies

F. Alt, B. Haynes, A. McMichael, 2022, Nature Reviews Immunology.

Emergence of a distinct HIV‐specific IL‐10‐producing CD8+ T‐cell subset with immunomodulatory functions during chronic HIV‐1 infection

I. Williams, A. McMichael, P. Borrow, 2013, European journal of immunology.

Immune perturbations in HIV-1–infected individuals who make broadly neutralizing antibodies

H. Liao, B. Haynes, D. Montefiori, 2016, Science Immunology.

CD4+ T follicular helper (Tfh) cells in human tonsil and blood are clonally convergent, but divergent from non-Tfh CD4+ cells. Brenna et al.

A. N. Davydov, A. McMichael, P. Borrow, 2019 .

HLA-E restricted, HIV-1 suppressing, Gag specific CD8+ T cells offer universal vaccine opportunities

L. Picker, A. McMichael, P. Borrow, 2020, bioRxiv.

Computational vaccinology: quantitative approaches.

Pingping Guan, Debra J. Taylor, Peter V Coveney, 2003, Novartis Foundation symposium.

Analysis of peptide-protein binding using amino acid descriptors: prediction and experimental verification for human histocompatibility complex HLA-A0201.

Pingping Guan, Darren R Flower, Persephone Borrow, 2005, Journal of medicinal chemistry.

Towards the chemometric dissection of peptide – HLA-A*0201 binding affinity: comparison of local and global QSAR models

Irini A. Doytchinova, Darren R. Flower, Valerie Walshe, 2005, J. Comput. Aided Mol. Des..

Epitope Specificity and Relative Clonal Abundance Do Not Affect CD8 Differentiation Patterns during Lymphocytic Choriomeningitis Virus Infection

P. Borrow, J. D. Di Santo, C. Evaristo, 2009, Journal of Virology.

Pathogen-derived HLA-E bound epitopes reveal broad primary anchor pocket tolerability and conformationally malleable peptide binding

L. Picker, A. McMichael, P. Borrow, 2018, Nature Communications.

Targeting autoantibodies in COVID-19

P. Borrow, I. Pedroza-Pacheco, 2021, Nature Reviews Immunology.

Analysis of the binding of hepatitis C virus genotype 1a and 1b E2 glycoproteins to peripheral blood mononuclear cell subsets.

P. Borrow, A. Tarr, J. Dubuisson, 2005, The Journal of general virology.

A trip down memory lane with Retrovirology

B. Berkhout, P. Borrow, F. Kirchhoff, 2019, Retrovirology.

Professor Mark Wainberg

B. Berkhout, P. Borrow, A. Fassati, 2017, Retrovirology.

Immune checkpoint modulation enhances HIV-1 antibody induction

F. Alt, Laura L. Sutherland, B. Haynes, 2020, Nature Communications.

Alterations in Receptor Binding Properties of Recent Human Influenza H3N2 Viruses Are Associated with Reduced Natural Killer Cell Lysis of Infected Cells

Rachel E. Owen, P. Borrow, W. Barclay, 2007, Journal of Virology.

Preexisting memory CD4+ T cells contribute to the primary response in an HIV-1 vaccine trial

B. Haynes, W. Fischer, N. Frahm, 2021, The Journal of clinical investigation.

The Host-Pathogen Interaction New Themes from Dendritic Cell Biology

P. Borrow, M. Rescigno, 2001, Cell.

Astroglial overproduction of TGF-β1 enhances inflammatory central nervous system disease in transgenic mice

L. Mucke, T. Wyss-Coray, P. Borrow, 1997, Journal of Neuroimmunology.

Antiretroviral Therapy Driven by Vaccination during Highly Active T Cell Expansions + HIV-1-Specific CD8 Broad TCR Usage in Functional

A. McMichael, P. Borrow, P. Bowness, 2007 .

Intracellular trafficking of HLA-E and its regulation

A. McMichael, P. Borrow, S. Brackenridge, 2023, The Journal of experimental medicine.

Loss of DNAM‐1 contributes to CD8+ T‐cell exhaustion in chronic HIV‐1 infection

J. Kappes, B. Haynes, I. Williams, 2010, European journal of immunology.

Immune checkpoint modulation enhances HIV-1 antibody induction

F. Alt, Laura L. Sutherland, B. Haynes, 2020, Nature Communications.

Empirical, AI, and QSAR Approaches to Peptide-MHC Binding Prediction

Channa K. Hattotuwagama, Pingping Guan, Matthew N. Davies, 2007 .

Characterization of secreted and intracellular forms of a truncated hepatitis C virus E2 protein expressed by a recombinant herpes simplex virus.

P. Klenerman, P. Borrow, M. Lucas, 2003, The Journal of general virology.

Chronic HIV infection affects the expression of the 2 transcription factors required for CD8 T-cell differentiation into cytolytic effectors.

I. Williams, G. Shaw, P. Borrow, 2012, Blood.

The Magnitude and Kinetics of the Mucosal HIV-Specific CD8+ T Lymphocyte Response and Virus RNA Load in Breast Milk

S. Meshnick, N. Letvin, P. Borrow, 2011, PloS one.

HLA-E–restricted SARS-CoV-2–specific T cells from convalescent COVID-19 patients suppress virus replication despite HLA class Ia down-regulation

P. Klenerman, A. McMichael, P. Borrow, 2023, Science Immunology.

Infection of lymphocytes by a virus that aborts cytotoxic T lymphocyte activity and establishes persistent infection

P. Borrow, M. Oldstone, A. Tishon, 1991, The Journal of experimental medicine.

Differential Immunodominance Hierarchy of CD8 (cid:2) T-Cell Responses in HLA-B * 27:05- and -B * 27:02-Mediated Control of HIV-1 Infection

B. Walker, M. John, S. Mallal, 2018 .

Differential Immunodominance Hierarchy of CD8 (cid:2) T-Cell Responses in HLA-B * 27:05- and -B * 27:02-Mediated Control of HIV-1 Infection

B. Walker, M. John, S. Mallal, 2018 .

HIV-1 Infection Functional Flexibility in HIV-2 Compared to Greater CD8+ TCR Heterogeneity and

H. Whittle, D. Flower, I. Williams, 2013 .

Mapping the epitopes of the Human Leukocyte Antigen E antibodies 3D12 and 4D12

A. McMichael, P. Borrow, S. Brackenridge, 2023, bioRxiv.

Pharmacological activation of the circadian component REV-ERB inhibits HIV-1 replication

P. Borrow, J. McKeating, P. Balfe, 2020, Scientific Reports.

CD4+ T follicular helper (Tfh) cells in human tonsil and blood are clonally convergent, but divergent from non-Tfh CD4+ cells

A. N. Davydov, A. McMichael, P. Borrow, 2019, bioRxiv.

Analysis of peptide-protein binding using amino acid descriptors: prediction and experimental verification for human histocompatibility complex HLA-A0201.

D. Flower, I. Doytchinova, P. Guan, 2005, Journal of medicinal chemistry.

Distinct patterns of hepcidin and iron regulation during HIV-1, HBV, and HCV infections

P. J. Norris, A. Prentice, I. Williams, 2014, Proceedings of the National Academy of Sciences.

Chronic HIV infection affects the expression of the 2 transcription factors required for CD8 T-cell differentiation into cytolytic effectors.

I. Williams, G. Shaw, P. Borrow, 2012, Blood.

Regulation of the cell surface expression of classical and non-classical MHC proteins by the human cytomegalovirus UL40 and rhesus cytomegalovirus rh67 proteins

P. Borrow, S. Brackenridge, A. McMichael, 2022, bioRxiv.

CD40L-deficient mice show deficits in antiviral immunity and have an impaired memory CD8+ CTL response

P. Borrow, M. Oldstone, A. Tishon, 1996, The Journal of experimental medicine.

Innate immunity against HIV: a priority target for HIV prevention research

P. Borrow, R. Shattock, A. Vyakarnam, 2010, Retrovirology.

Vertical T cell immunodominance and epitope entropy determine HIV-1 escape.

A. Perelson, B. Korber, P. Hraber, 2012, Journal of Clinical Investigation.

Resistance to type 1 interferons is a major determinant of HIV-1 transmission fitness

G. Learn, B. Haynes, P. Sharp, 2017, Proceedings of the National Academy of Sciences.

MARS an improved de novo peptide candidate selection method for non-canonical antigen target discovery in cancer

Isaac B. Woodhouse, P. Borrow, L. Eisenlohr, 2024, Nature communications.

In Silico Immunology

Channa K. Hattotuwagama, Debra J. Taylor, Shelley L. Hemsley, 2007 .

Circulating inflammatory biomarkers can predict and characterize tuberculosis-associated immune reconstitution inflammatory syndrome

L. Haddow, P. Easterbrook, P. Borrow, 2011, AIDS.

A high affinity monoclonal antibody against HLA-E-VL9 enhances natural killer cell anti-tumor killing

P. Borrow, S. Brackenridge, W. Rountree, 2024, bioRxiv.

MAPPING THE EPITOPES OF THE 1 HUMAN LEUKOCYTE ANTIGEN E 2 ANTIBODIES 3D12 AND 4D12

P. Borrow, S. Brackenridge, Andrew J. McMichael, 2022 .