D. Margulies

发表

Chemical input multiplicity facilitates arithmetical processing.

A. Shanzer, D. Margulies, G. Melman, 2004, Journal of the American Chemical Society.

A molecular full-adder and full-subtractor, an additional step toward a moleculator.

A. Shanzer, D. Margulies, G. Melman, 2006, Journal of the American Chemical Society.

Crystal structure of a lectin-like natural killer cell receptor bound to its MHC class I ligand

D. Margulies, R. Mariuzza, J. Tormo, 1999, Nature.

Lipopolysaccharide-Induced CD300b Receptor Binding to Toll-like Receptor 4 Alters Signaling to Drive Cytokine Responses that Enhance Septic Shock.

J. Coligan, D. Margulies, Chen-feng Qi, 2016, Immunity.

Genetic engineering of an H-2Dd/Q10b chimeric histocompatibility antigen: purification of soluble protein from transformant cell supernatants.

D. Margulies, J. McCluskey, A. L. Ramsey, 1986, Proceedings of the National Academy of Sciences of the United States of America.

Role of conserved regions of class I MHC molecules in the activation of CD8+ cytotoxic T lymphocytes by peptide and purified cell-free class I molecules.

C. DeLisi, J. Berzofsky, D. Margulies, 1993, International immunology.

A molecular keypad lock: a photochemical device capable of authorizing password entries.

Galina Melman, Abraham Shanzer, Clifford E Felder, 2007, Journal of the American Chemical Society.

Targeted protein surface sensors as a tool for analyzing small populations of proteins in biological mixtures.

D. Margulies, Leila Motiei, Zohar Pode, 2014, Angewandte Chemie.

Authorizing multiple chemical passwords by a combinatorial molecular keypad lock.

Leila Motiei, D. Margulies, M. Iron, 2013, Journal of the American Chemical Society.

Protein recognition by an ensemble of fluorescent DNA G-quadruplexes.

D. Margulies, A. Hamilton, 2009, Angewandte Chemie.

Digital analysis of protein properties by an ensemble of DNA quadruplexes.

Andrew D. Hamilton, D. Margulies, A. Hamilton, 2009, Journal of the American Chemical Society.

Enhanced antigen-specific antitumor immunity with altered peptide ligands that stabilize the MHC-peptide-TCR complex.

E. Jaffee, D. Margulies, D. Pardoll, 2000, Immunity.

Peptide libraries define the fine specificity of anti-polysaccharide antibodies to Cryptococcus neoformans.

D. Margulies, G. Nussbaum, L. Boyd, 1996, Journal of molecular biology.

Availability of autoantigenic epitopes controls phenotype, severity, and penetrance in TCR Tg autoimmune gastritis

D. Margulies, E. Shevach, K. Natarajan, 2008, European journal of immunology.

The Neuronal Migration Factor srGAP2 Achieves Specificity in Ligand Binding through a Two-Component Molecular Mechanism.

D. Margulies, Y. Opatowsky, J. Guez-Haddad, 2015, Structure.

The structure of mouse cytomegalovirus m04 protein obtained from sparse NMR data reveals a conserved fold of the m02-m06 viral immune modulator family.

A. Bax, Jinfa Ying, D. Margulies, 2014, Structure.

Determinant selection of major histocompatibility complex class I- restricted antigenic peptides is explained by class I-peptide affinity and is strongly influenced by nondominant anchor residues

D. Margulies, J. McCluskey, S Khilko, 1994, The Journal of experimental medicine.

An allosteric mechanism controls antigen presentation by the H-2K(b) complex.

D. Margulies, J. Strominger, D. Davis, 1999, Biochemistry.

Antibodies Directed Against the MHC-I Molecule H-2Dd Complexed with an Antigenic Peptide: Similarities to a T Cell Receptor with the Same Specificity1

I. M. Belyakov, J. Berzofsky, D. Margulies, 2000, The Journal of Immunology.

Different Vaccine Vectors Delivering the Same Antigen Elicit CD8+ T Cell Responses with Distinct Clonotype and Epitope Specificity1

D. Douek, D. Margulies, G. Nabel, 2009, The Journal of Immunology.

CD28, Costimulator or Agonist Receptor?

D. Margulies, 2003, The Journal of experimental medicine.

Decorating bacteria with self-assembled synthetic receptors

T. Salame, D. Margulies, T. Unger, 2020, Nature Communications.

An allosteric site in the T-cell receptor Cβ domain plays a critical signalling role

Peter Schuck, Huaying Zhao, Ad Bax, 2017, Nature Communications.

Structure and Function of Molecular Chaperones that Govern Immune Peptide Loading.

D. Margulies, K. Natarajan, Jiansheng Jiang, 2019, Sub-cellular biochemistry.

MHC Molecules, T cell Receptors, Natural Killer Cell Receptors, and Viral Immunoevasins-Key Elements of Adaptive and Innate Immunity.

D. Margulies, K. Natarajan, Jiansheng Jiang, 2019, Advances in experimental medicine and biology.

The Role of Molecular Flexibility in Antigen Presentation and T Cell Receptor-Mediated Signaling

A. Bax, D. Margulies, N. Sgourakis, 2018, Front. Immunol..

Excess β2 microglobulin promoting functional peptide association with purified soluble class I MHC molecules

J. Berzofsky, R. Germain, D. Margulies, 1991, Nature.

T cell receptor-MHC class I peptide interactions: affinity, kinetics, and specificity.

Young Sang Kim, D. Margulies, M. Corr, 1994, Science.

Molecular Logic as a Means to Assess Therapeutic Antidotes

D. Margulies, Leila Motiei, Linor Unger-Angel, 2019, Front. Chem..

TCR avidity: it's not how strong you make it, it's how you make it strong

D. Margulies, 2001, Nature Immunology.

Measuring interactions of MHC class I molecules using surface plasmon resonance.

D. Margulies, M. Corr, A. Bothwell, 1995, Journal of immunological methods.

Alterations in the HLA-B*57:01 Immunopeptidome by Flucloxacillin and Immunogenicity of Drug-Haptenated Peptides

Zhihua Li, D. Margulies, W. Hildebrand, 2021, Frontiers in Immunology.

Faculty Opinions recommendation of A major histocompatibility complex-peptide-restricted antibody and t cell receptor molecules recognize their target by distinct binding modes: crystal structure of human leukocyte antigen (HLA)-A1-MAGE-A1 in complex with FAB-HYB3.

D. Margulies, 2004 .

MHC‐restricted Ag85B‐specific CD8+ T cells are enhanced by recombinant BCG prime and DNA boost immunization in mice

D. Margulies, S. Hayakawa, S. Komine-Aizawa, 2019, European journal of immunology.

Assessing changes in the expression levels of cell surface proteins with a turn-on fluorescent molecular probe.

D. Margulies, T. Unger, T. Dadosh, 2021, Chemical communications.

Chimeric Anti-Staphylococcal Enterotoxin B Antibodies and Lovastatin Act Synergistically to Provide In Vivo Protection against Lethal Doses of SEB

D. Margulies, B. Osborne, K. Natarajan, 2011, PloS one.

Studying interactions involving the T-cell antigen receptor by surface plasmon resonance.

D. Margulies, M. Jelonek, S. Khilko, 1996, Current opinion in immunology.

MHC Class I/peptide interactions: Binding specificity and kinetics

D. Margulies, M. Corr, L. Boyd, 1993, Journal of molecular recognition : JMR.

Functional cell surface expression by a recombinant single‐chain class I major histocompatibility complex molecule with a cis‐active β2‐microglobulin domain

D. Margulies, S. Kozlowski, L. McHugh, 1994, European journal of immunology.

Lack of strict correlation of functional sensitization with the apparent affinity of MHC/peptide complexes for the TCR.

D. Margulies, A. Bothwell, L. Boyd, 1995, Journal of immunology.

Ly49A allelic variation and MHC class I specificity

D. Margulies, W. Yokoyama, J. Roland, 2001, Immunogenetics.

Host MHC class I molecules modulate in vivo expression of a NK cell receptor.

D. Margulies, W. Yokoyama, R. Hunziker, 1994, Journal of immunology.

Crystal structure of human CD69: a C-type lectin-like activation marker of hematopoietic cells.

D. Margulies, R. Mariuzza, K. Natarajan, 2000, Biochemistry.

Interaction of TAPBPR, a tapasin homolog, with MHC-I molecules promotes peptide editing

D. Margulies, Curtis McMurtrey, W. Hildebrand, 2016, Proceedings of the National Academy of Sciences.

Inhibition of an allospecific T cell hybridoma by soluble class I proteins and peptides: Estimation of the affinity of a T cell receptor for MHC

J. Coligan, D. Margulies, W. Maloy, 1989, Cell.

A recombinant, soluble, single-chain class I major histocompatibility complex molecule with biological activity.

D. Margulies, M. Corr, S. Kozlowski, 1992, Proceedings of the National Academy of Sciences of the United States of America.

The cellular environment regulates in situ kinetics of T‐cell receptor interaction with peptide major histocompatibility complex

D. Margulies, K. Natarajan, Cheng Zhu, 2015, European journal of immunology.

The lectin-like NK cell receptor Ly-49A recognizes a carbohydrate-independent epitope on its MHC class I ligand.

D. Margulies, J. Abastado, N. Matsumoto, 1998, Immunity.

This information is current as Specificity with Distinct Clonotype and Epitope T Cell Responses + Same Antigen Elicit CD 8 Different Vaccine Vectors Delivering the

D. Douek, D. Margulies, G. Nabel, 2009 .

Peptide-Protein Interactions

D. Margulies, K. Natarajan, M. Jelonek, 2000 .

Serum Angiotensin-1 Conver~_'ng Enzyme Activity Processes a Human Immunodeficiency Virus 1 gp160 Peptide for Presentation by Major Histocompatibility Complex Class I Molecules By Steven Kozlowski,* Maripat Corr,* Toshiyuki Takeshita,$

J. Berzofsky, R. Germain, D. Margulies, 1992 .

Serum angiotensin-1 converting enzyme activity processes a human immunodeficiency virus 1 gp160 peptide for presentation by major histocompatibility complex class I molecules

J. Berzofsky, R. Germain, D. Margulies, 1992, The Journal of experimental medicine.

Protein recognition by a pattern-generating fluorescent molecular probe.

D. Margulies, T. Unger, B. Markus, 2017, Nature nanotechnology.

Crystal structure of a TAPBPR–MHC I complex reveals the mechanism of peptide editing in antigen presentation

D. Margulies, K. Natarajan, Jiansheng Jiang, 2017, Science.

Analyzing Amyloid Beta Aggregates with a Combinatorial Fluorescent Molecular Sensor.

D. Margulies, Leila Motiei, Joydev Hatai, 2017, Journal of the American Chemical Society.

Induction of Immune Responses

D. Margulies, 2009 .

Induction of Immune Responses

D. Margulies, 2000 .

Induction of Immune Responses

D. Margulies, 2000 .

Control of autoimmunity by regulatory T cells.

D. Margulies, E. Shevach, K. Natarajan, 2001, Advances in experimental medicine and biology.

Crystal structure of the murine cytomegalovirus MHC-I homolog m144.

D. Margulies, R. Guan, R. Mariuzza, 2005, Journal of molecular biology.

Direct interaction of the mouse cytomegalovirus m152/gp40 immunoevasin with RAE-1 isoforms.

D. Margulies, S. Jonjić, P. Brown, 2010, Biochemistry.

Cutting Edge: Inhibition of the Interaction of NK Inhibitory Receptors with MHC Class I Augments Antiviral and Antitumor Immunity

D. Margulies, E. Shevach, K. Natarajan, 2020, The Journal of Immunology.

Variable MHC class I engagement by Ly49 natural killer cell receptors demonstrated by the crystal structure of Ly49C bound to H-2Kb

D. Margulies, R. Guan, R. Mariuzza, 2003, Nature Immunology.

Binding of the Natural Killer Cell Inhibitory Receptor Ly49A to Its Major Histocompatibility Complex Class I Ligand

D. Margulies, R. Mariuzza, J. Tormo, 2002, The Journal of Biological Chemistry.

Structural requirements for class I MHC molecule-mediated antigen presentation and cytotoxic T cell recognition of an immunodominant determinant of the human immunodeficiency virus envelope protein

J. Berzofsky, B. Moss, R. Germain, 1989, The Journal of experimental medicine.

Expression of H-2Dd and H-2Ld mouse major histocompatibility antigen genes in L cells after DNA-mediated gene transfer.

J. Seidman, G. Evans, E. Appella, 1983, Journal of immunology.

Molecular analysis of the same HIV peptide functionally binding to both a class I and a class II MHC molecule.

D. Margulies, S. Kozlowski, C. D. Pendleton, 1995, Journal of immunology.

Mice transgenic for a gene that encodes a soluble, polymorphic class I MHC antigen.

D. Margulies, R. Hunziker, 1991, Biotechnology.

This information is current as Receptor with the Same Specificity Antigenic Peptide: Similarities to a T Cell Complexed with an d Molecule H-2D Antibodies Directed Against the MHC-I

J. Berzofsky, D. Margulies, D. Chung, 2012 .

Fluorescent Labelling of Cell Surface Proteins on a Solid Support

D. Margulies, H. Cohen, Leila Motiei, 2021 .

Steps toward enhancing the fluorescence of small-molecule-based protein labels using supramolecular hosts

D. Margulies, Leila Motiei, P. K. Prasad, 2021 .

Functional expression of a transfected murine class II MHC gene

R. Germain, D. Margulies, M. Norcross, 1983, Nature.

Home schooling of NK cells.

D. Margulies, 2009, Immunity.

Interact with NK and TCR d Molecule : Distinct Sites of H-2 DdH-2 D NK and CTL Recognition of a Single Chain

I. M. Belyakov, J. Berzofsky, D. Margulies, 1999 .

A family of murine NK cell receptors specific for target cell MHC class I molecules.

D. Margulies, W. Seaman, W. Yokoyama, 1995, Seminars in immunology.

Spontaneous Organ-Specific Th2-Mediated Autoimmunity in TCR Transgenic Mice

D. Margulies, E. Shevach, K. Natarajan, 2004, The Journal of Immunology.

Autoimmunity in TCR Transgenic Mice Spontaneous Organ-Specific Th 2-Mediated Margulies

D. Margulies, E. Shevach, K. Natarajan, 2004 .

How MHC molecules grab citrullinated peptides to foster rheumatoid arthritis

D. Margulies, 2018, The Journal of Biological Chemistry.

Allospecific and virus-specific cytolytic T lymphocytes are restricted to the N or C1 domain of H-2 antigens expressed on L cells after DNA-mediated gene transfer.

J. Seidman, G. Evans, D. Margulies, 1983, Proceedings of the National Academy of Sciences of the United States of America.

Somatic cell hybridization of mouse myeloma cells

D. Margulies, W. Kuehl, M. Scharff, 1976, Cell.

Exon shuffling: New genes from old

D. Margulies, J. McCluskey, 1985, Survey of immunologic research.

Hybrid H-2 histocompatibility gene products assign domains recognized by alloreactive T cells.

J. Seidman, G. Evans, D. Margulies, 1983, Proceedings of the National Academy of Sciences of the United States of America.

Molecular interactions: stiff or floppy (or somewhere in between?).

D. Margulies, 2003, Immunity.

"Exon-shuffling" maps control of antibody- and T-cell-recognition sites to the NH2-terminal domain of the class II major histocompatibility polypeptide A beta.

R. Germain, D. Margulies, R. Lechler, 1985, Proceedings of the National Academy of Sciences of the United States of America.

A targeted glucocorticoid receptor antisense transgene increases thymocyte apoptosis and alters thymocyte development.

D. Margulies, J. Ashwell, M. Vacchio, 1995, Immunity.

Membrane Ia expression and antigen-presenting accessory cell function of L cells transfected with class II major histocompatibility complex genes

R. Germain, D. Margulies, D. M. Bentley, 1984, The Journal of experimental medicine.

H–2-like genes in the Tla region of mouse chromosome 17

J. Seidman, G. Evans, D. Margulies, 1982, Nature.

Engineering soluble major histocompatibility molecules: Why and how

D. Margulies, J. McCluskey, L. Boyd, 1987, Immunologic research.

The role of CD4/L3T4 in T-lymphocyte function.

R. Germain, D. Margulies, A. Singer, 1987, Annales de l'Institut Pasteur. Immunology.

A recombinant single-chain HLA-A2.1 molecule, with a cis active beta-2-microglobulin domain, is biologically active in peptide binding and antigen presentation.

D. Margulies, M. Mage, D. Loftus, 1996, Human immunology.

Two intermediate-avidity cytotoxic T lymphocyte clones with a disparity between functional avidity and MHC tetramer staining.

J. Berzofsky, D. Margulies, M. Derby, 2001, International immunology.

Structure and expression of a mouse major histocompatibility antigen gene , H 2 Ld ( gene cloning / transformation / nucleotide sequence )

J. Seidman, G. Evans, D. Margulies, 2022 .

Multivalent requirement for the stimulation of alloreactive T cells: studies with engineered soluble MHC class I proteins in vitro and in vivo.

D. Margulies, J. McCluskey, L. Kjer-Nielsen, 1990 .

Peptides tailored to perfection?

D. Margulies, 1992, Current Biology.

Naked or peptide-clothed MHC?

D. Margulies, 1989, Nature.

Inhibition of allorecognition by an H-2Kb-derived peptide is evidence for a T-cell binding region on a major histocompatibility complex molecule.

J. Coligan, D. Margulies, A. Singer, 1989, Proceedings of the National Academy of Sciences of the United States of America.

Synthetic nanobody–SARS-CoV-2 receptor-binding domain structures identify distinct epitopes

D. Margulies, K. Natarajan, Jiansheng Jiang, 2021, bioRxiv.

CD300b regulates the phagocytosis of apoptotic cells via phosphatidylserine recognition

J. Coligan, D. Margulies, Y. Murakami, 2014, Cell Death and Differentiation.

T cell activation by purified, soluble, class I MHC molecules. Requirement for polyvalency.

D. Margulies, J. McCluskey, J. Inman, 1988, Journal of immunology.

The HLA-B14 peptide binding site can accommodate peptides with different combinations of anchor residues.

K. Parker, J. Coligan, J. Shiloach, 1994, The Journal of biological chemistry.

Cell surface expression of an in vitro recombinant class II/class I major histocompatibility complex gene product

R. Germain, D. Margulies, J. McCluskey, 1985, Cell.

Independent and synergistic effects of disulfide bond formation, beta 2-microglobulin, and peptides on class I MHC folding and assembly in an in vitro translation system.

D. Margulies, R. Ribaudo, 1992, Journal of immunology.

T-cell recognition of a chimaeric class II/class I MHC molecule and the role of L3T4

R. Germain, D. Margulies, A. Singer, 1985, Nature.

Rapid Induction of Apoptosis in CD8+ HIV-1 Envelope-Specific Murine CTLs by Short Exposure to Antigenic Peptide1

J. Berzofsky, D. Margulies, Y. Nakagawa, 2002, The Journal of Immunology.

Control of expression of histocompatibility antigens (H-2) and beta 2-microglobulin in F9 teratocarcinoma stem cells.

J. Seidman, C. Croce, E. Appella, 1981, Proceedings of the National Academy of Sciences of the United States of America.

Combinatorial protein recognition as an alternative approach to antibody-mimetics.

D. Margulies, A. Hamilton, 2010, Current opinion in chemical biology.

Immunochemical analysis of a recombinant, genetically engineered, secreted HLA-A2/Q10b fusion protein.

D. Margulies, H. Sollinger, W. Burlingham, 1991, Human immunology.

Potent Neutralization of Staphylococcal Enterotoxin B by Synergistic Action of Chimeric Antibodies

D. Ratner, D. Margulies, B. Osborne, 2010, Infection and Immunity.

The natural killer cell receptor Ly-49A recognizes a peptide-induced conformational determinant on its major histocompatibility complex class I ligand.

D. Margulies, W. Yokoyama, M. Orihuela, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Plasmacytomas and Hybridomas

D. Margulies, B. Diamond, M. Scharff, 1980 .

Structural mechanism of tapasin-mediated MHC-I peptide loading in antigen presentation

P. Cresswell, D. Margulies, N. Sgourakis, 2022, Nature Communications.

Structural and dynamic studies of TAPBPR and Tapasin reveal the mechanism of peptide loading of MHC-I molecules.

D. Margulies, K. Natarajan, Jiansheng Jiang, 2020, Current opinion in immunology.

Protein surface recognition with targeted fluorescent molecular probes

D. Margulies, Leila Motiei, Yael Nissinkorn, 2016 .

Protein surface recognition with targeted fluorescent molecular sensors

D. Margulies, Leila Motiei, Yael Nissinkorn, 2016 .

Potent monoclonal antibodies neutralize Omicron sublineages and other SARS-CoV-2 variants

D. Margulies, E. Postnikova, Baoshan Zhang, 2022, Cell Reports.

Generation of anti-SARS CoV-2 monoclonal antibodies (mAbs) In vitro neutralization of SARS-CoV-2 variants Structural analysis In vivo animal studies

D. Margulies, T. Stephens, U. Buchholz, 2022 .

The biochemistry and cell biology of antigen processing and presentation.

R. Germain, D. Margulies, 1993, Annual review of immunology.

Letter to the Editor: Backbone and side chain resonance assignmentsof a TRAV14-3 mouse T cell receptor domain

D. Margulies, Jin-Shan Hu, D. Plaksin, 2005, Journal of biomolecular NMR.

Resistance to viral infection by intraepithelial lymphocytes in HIV-1 P18-I10-specific T-cell receptor transgenic mice.

D. Margulies, Y. Nakagawa, M. Shimizu, 2004, Biochemical and biophysical research communications.

Role of alpha3 domain of class I MHC molecules in the activation of high- and low-avidity CD8+ CTLs.

I. M. Belyakov, J. Berzofsky, D. Margulies, 2007, International immunology.

Role of a 3 domain of class I MHC molecules in the activation of high- and low-avidity CD8 1 CTLs

I. M. Belyakov, J. Berzofsky, D. Margulies, 2007 .

Exposure to Antigenic Peptide Envelope-Specific Murine CTLs by Short HIV-1 + Rapid Induction of Apoptosis in CD 8

J. Berzofsky, D. Margulies, Y. Nakagawa, 2002 .

Cell surface expression of the amino-terminal domain of A kappa alpha. Recognition of an isolated MHC antigenic structure by allospecific T cells but not alloantibodies.

J. Coligan, R. Germain, D. Margulies, 1988, Journal of immunology.

A Single Residue, Arginine 65, Is Critical for the Functional Interaction of Leukocyte-Associated Inhibitory Receptor-1 with Collagens1

J. Coligan, D. Margulies, Sriram Narayanan, 2009, The Journal of Immunology.

Analysis of hybrid H-2D and L antigens with reciprocally mismatched aminoterminal domains: functional T cell recognition requires preservation of fine structural determinants.

D. Margulies, J. Bluestone, J. McCluskey, 1986, Journal of immunology.

Serologic and T cell recognition of truncated transplantation antigens encoded by in vitro deleted class I major histocompatibility genes.

J. Coligan, D. Margulies, J. Bluestone, 1986, Journal of immunology.

Mutations in mouse myeloma cells: implications for human multiple myeloma and the production of immunoglobulins.

D. Margulies, M. Scharff, S. Weitzman, 1976, Annals of internal medicine.

THE USE OF MUTANT MYELOMA CELLS TO EXPLORE THE PRODUCTION OF IMMUNOGLOBULINS

S. Morrison, D. Margulies, W. Kuehl, 1975 .

Structure and function of murine cytomegalovirus MHC-I-like molecules: how the virus turned the host defense to its advantage

D. Margulies, K. Natarajan, A. Redwood, 2009, Immunologic research.

Rigidification of the alpha2 helix of an MHC class I molecule by a valine to proline mutation in position 165 does not prevent peptide-specific antigen presentation.

D. Margulies, M. Mage, D. Plaksin, 1997, Journal of immunology.

Medication detection by a combinatorial fluorescent molecular sensor.

D. Margulies, M. Iron, David Margulies, 2012, Angewandte Chemie.

Protein recognition by bivalent, ‘turn-on’ fluorescent molecular probes† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c5sc01038a Click here for additional data file.

M. Eisenstein, D. Margulies, B. Rout, 2015, Chemical science.

Sensing Protein Surfaces with Targeted Fluorescent Receptors.

S. Albeck, D. Margulies, A. Rabinkov, 2015, Chemistry.

Structure and function of natural killer cell receptors: multiple molecular solutions to self, nonself discrimination.

D. Margulies, R. Mariuzza, K. Natarajan, 2002, Annual review of immunology.

Preface

J. Coligan, D. Margulies, E. Shevach, 2012 .

Structural basis of MHC class I recognition by natural killer cell receptors

D. Margulies, R. Mariuzza, K. Natarajan, 2001, Immunological reviews.

A simple method for polyethylene glycol-promoted hybridization of mouse myeloma cells

D. Margulies, M. Gefter, M. Scharff, 1977, Somatic cell genetics.

Minimal requirements for peptide mediated activation of CD8+ CTL.

R C Brower, C. DeLisi, J. Berzofsky, 1994, Molecular immunology.

Structure and expression of a mouse major histocompatibility antigen gene, H-2Ld.

J. Seidman, G. Evans, D. Margulies, 1982, Proceedings of the National Academy of Sciences of the United States of America.

Broad Applications of Thiazole Orange in Fluorescent Sensing of Biomolecules and Ions

D. Margulies, Leila Motiei, Ohad Suss, 2021, Molecules.

Class I MHC/Peptide/ β2-Microglobulin Interactions:The Basis of Cytotoxic T-Cell Recognition

D. Margulies, M. Corr, L. Boyd, 1993 .

Stimulation of inducer T lymphocytes to undergo clonal expansion and differ- entiation requires recognition of nominal antigen in the context of polymorphic determinants of class II major histocompatibility complex (MHC) 1 glycoproteins

D. Margulies, D. M. Bentley, M. Norcross, 2003 .

MHC: Structure and Function

D. Margulies, S. Candon, 2004 .

The X-ray crystal structure of a Valpha2.6Jalpha38 mouse T cell receptor domain at 2.5 A resolution: alternate modes of dimerization and crystal packing.

E. Padlan, J. Navaza, D. Margulies, 1999, Journal of molecular biology.

Three-dimensional structure of H-2Dd complexed with an immunodominant peptide from human immunodeficiency virus envelope glycoprotein 120.

D. Margulies, E. Malchiodi, R. Mariuzza, 1998, Journal of molecular biology.

A T cell receptor V alpha domain expressed in bacteria: does it dimerize in solution?

A. Bax, E. Padlan, D. Margulies, 1996, The Journal of experimental medicine.

A T cell receptor V alpha domain expressed in bacteria: does it dimerize in solution?

A. Bax, E. Padlan, D. Margulies, 1996, The Journal of experimental medicine.

Molecular Biology

D. Margulies, 2010 .

Post‐thymectomy autoimmune gastritis: fine specificity and pathogenicity of anti‐H/K ATPase‐ reactive T cells

D. Margulies, E. Shevach, K. Natarajan, 1999, European journal of immunology.

Signals controlling alternative splicing of major histocompatibility complex H-2 class I pre-mRNA

J. Coligan, D. Margulies, J. McCluskey, 2004, Immunogenetics.

A Serine/Threonine Phosphorylation Site in the Ectodomain of a T Cell Receptor β Chain is Required for Activation by Superantigen

D. Margulies, M. Sitkovsky, C. Caldwell, 2003, Journal of receptor and signal transduction research.

Artificial signal transduction therapy: a futuristic approach to disease treatment.

D. Margulies, Leila Motiei, R. Peri-Naor, 2015, Future medicinal chemistry.

bca: an activation-related B-cell gene.

D. Margulies, L. Shapiro, P. Cohen, 1998, Molecular immunology.

Structural aspects of chaperone-mediated peptide loading in the MHC-I antigen presentation pathway

D. Margulies, K. Natarajan, Jiansheng Jiang, 2019, Critical reviews in biochemistry and molecular biology.

Exon shuffling: mapping polymorphic determinants on hybrid mouse transplantation antigens

J. Seidman, G. Evans, D. Margulies, 1982, Nature.

Failure of signaling through a chimeric class I-immunoglobulin molecule expressed on the surface of transfected B lymphoma cells and cells of transgenic mice.

W. Paul, D. Margulies, J. Mizuguchi, 1992, Cellular immunology.

H‐2 hemizygous mutants from a heterozygous cell line: role of mitotic recombination.

J. Seidman, G. Evans, D. Margulies, 1983, The EMBO journal.

A "chimeric" C57l-derived Ly49 inhibitory receptor resembling the Ly49D activation receptor.

D. Margulies, W. Yokoyama, H. Smith, 2001, Cellular immunology.

A transgenic mouse model for HLA‐B*57:01‐linked abacavir drug tolerance and reactivity

D. Margulies, K. Natarajan, M. Cardone, 2018, The Journal of clinical investigation.

Avidity of CD8 T cells sharpens immunodominance.

J. Berzofsky, D. Margulies, A. Dzutsev, 2007, International immunology.

Identification of the peptide binding motif for HLA-B44, one of the most common HLA-B alleles in the Caucasian population.

K. Parker, J. Coligan, J. Shiloach, 1995, Biochemistry.

Multiple pathways are involved in the extracellular processing of MHC class I-restricted peptides.

J. Berzofsky, D. Margulies, M. Corr, 1993, Journal of immunology.

Abacavir induces loading of novel self-peptides into HLA-B*57: 01 an autoimmune model for HLA-associated drug hypersensitivity

D. Margulies, Curtis McMurtrey, W. Hildebrand, 2012, AIDS.

MHC class I molecules, structure and function.

D. Margulies, R. Mariuzza, K. Natarajan, 1999, Reviews in immunogenetics.

Cytotoxic T lymphocyte recognition of class I H-2 antigens after DNA-mediated gene transfer.

J. Seidman, G. Evans, D. Margulies, 1984, Federation proceedings.

Structure and function of murine class II major histocompatibility complex genes.

R. Germain, W. Paul, D. Margulies, 1986, The Mount Sinai journal of medicine, New York.

Competitive Inhibition In Vivo and Skewing of the T Cell Repertoire of Antigen-Specific CTL Priming by an Anti-Peptide-MHC Monoclonal Antibody

J. Berzofsky, D. Margulies, D. Chung, 2001, The Journal of Immunology.

Class I Genes of the major histocompatibility complex

G. Evans, D. Margulies, 1983, Survey of immunologic research.

The extracellular domains of MHC class II molecules determine their processing requirements for antigen presentation.

D. Margulies, J. McCluskey, L. Kjer-Nielsen, 1990, Journal of immunology.

Endogenous peptides of a soluble major histocompatibility complex class I molecule, H-2Lds: sequence motif, quantitative binding, and molecular modeling of the complex

E. Padlan, D. Margulies, M. Corr, 1992, The Journal of experimental medicine.

The products of transferred H-2 genes express determinants that restrict hapten-specific cytotoxic T cells.

J. Seidman, G. Evans, D. Margulies, 1983, Journal of immunology.

Interactions of TCRs with MHC-peptide complexes: a quantitative basis for mechanistic models.

D. Margulies, 1997, Current opinion in immunology.

Split tolerance to the MHC class I molecule H-2Dd in animals transgenic for its soluble analog.

D. Margulies, E. Shevach, R. Hunziker, 1997, Human immunology.

Activating CTL precursors to reveal CTL function without skewing the repertoire by in vitro expansion

J. Berzofsky, D. Margulies, J. Cox, 2001, European journal of immunology.

MHC class I recognition by Ly49 natural killer cell receptors.

D. Margulies, R. Mariuzza, K. Natarajan, 2002, Molecular immunology.

A three-domain T cell receptor is biologically active and specifically stains cell surface MHC/peptide complexes.

D. Margulies, P. McPhie, D. Plaksin, 1997, Journal of immunology.

T-cell receptors: Feeling out the complex

E. Padlan, D. Margulies, 1997, Current Biology.

CD8 expression alters the fine specificity of an alloreactive MHC class I-specific T hybridoma.

D. Margulies, L. Pease, J. McCluskey, 1992, International immunology.

The TLR3 signaling complex forms by cooperative receptor dimerization

D. Davies, R. Ghirlando, D. Margulies, 2008, Proceedings of the National Academy of Sciences.

MHC‐restricted Ag85B‐specific CD8+ T cells are enhanced by recombinant BCG prime and DNA boost immunization in mice

D. Margulies, S. Hayakawa, S. Komine-Aizawa, 2018, European journal of immunology.

Direct binding of the MHC class I molecule H-2Ld to CD8: interaction with the amino terminus of a mature cell surface protein.

D. Margulies, P. Hudson, M. Jelonek, 1998, Journal of immunology.

Terminus of a Mature Cell Surface Protein to CD 8 : Interaction with the AminodH-2 L Direct Binding of the MHC Class I Molecule

D. Margulies, P. Hudson, M. Jelonek, 1998 .

Fluorescein as a model molecular calculator with reset capability

David Margulies, Galina Melman, Abraham Shanzer, 2005, Nature materials.

Structural basis of mouse cytomegalovirus m152/gp40 interaction with RAE1γ reveals a paradigm for MHC/MHC interaction in immune evasion

D. Margulies, K. Natarajan, H. Robinson, 2012, Proceedings of the National Academy of Sciences.

How the Virus Outsmarts the Host: Function and Structure of Cytomegalovirus MHC-I-Like Molecules in the Evasion of Natural Killer Cell Surveillance

D. Margulies, K. Natarajan, M. Revilleza, 2011, Journal of biomedicine & biotechnology.

Phosphorylation of Extracellular Domains of T-Lymphocyte Surface Proteins

D. Margulies, M. Sitkovsky, M. Jelonek, 1996, The Journal of Biological Chemistry.

Alternative processing of H‐2Dd pre‐mRNAs results in membrane expression of differentially phosphorylated protein products.

J. Coligan, D. Margulies, J. McCluskey, 1986, The EMBO journal.

Regulation of immunoglobulin expression in mouse myeloma cells.

S. Morrison, D. Margulies, M. Gefter, 1977, Cold Spring Harbor symposia on quantitative biology.

Mapping the Ligand of the NK Inhibitory Receptor Ly49A on Living Cells

D. Margulies, R. Mariuzza, K. Natarajan, 2000, The Journal of Immunology.

Receptor Ly 49 A on Living Cells Mapping the Ligand of the NK Inhibitory

D. Margulies, R. Mariuzza, J. Tormo, 2000 .

An affinity for learning

D. Margulies, David H. Margulies, 1996, Nature.

A T cell receptor transgenic model of severe, spontaneous organ‐specific autoimmunity

D. Margulies, E. Shevach, K. Natarajan, 2001, European journal of immunology.

Surface Binding Inhibitors of the SCF–KIT Protein–Protein Interaction

D. Margulies, I. Lax, J. Schlessinger, 2009, Chembiochem : a European journal of chemical biology.

Peptide exchange on MHC-I by TAPBPR is driven by a negative allostery release cycle

D. Margulies, E. L. Kovrigin, N. Sgourakis, 2018, Nature Chemical Biology.

A Novel MHC-I Surface Targeted for Binding by the MCMV m06 Immunoevasin Revealed by Solution NMR*

A. Bax, Jinfa Ying, D. Margulies, 2015, The Journal of Biological Chemistry.

T cell receptor-MHC class I peptide interactions: affinity, kinetics, and specificity.

D. Margulies, M. Corr, S. Maher, 1994, Science.

Interaction of the NK cell inhibitory receptor Ly49A with H-2Dd: identification of a site distinct from the TCR site.

D. Margulies, K. Natarajan, P. Schuck, 1999, Immunity.

H-2Dd exploits a four residue peptide binding motif

E. Padlan, D. Margulies, M. Corr, 1993, The Journal of experimental medicine.

Solution binding of an antigenic peptide to a major histocompatibility complex class I molecule and the role of beta 2-microglobulin.

D. Margulies, L. Boyd, S. Kozlowski, 1992, Proceedings of the National Academy of Sciences of the United States of America.

Ligand‐Receptor Interactions in the Immune System

D. Margulies, 2003 .

The Peptide-Receptive Transition State of MHC Class I Molecules: Insight from Structure and Molecular Dynamics

D. Margulies, K. Natarajan, H. Robinson, 2012, The Journal of Immunology.

Estimation of low frequency antigen-presenting cells with a novel RELISPOT assay.

J. Berzofsky, A. Dzutsev, D. Margulies, 2008, Journal of immunological methods.

Linkage of beta 2-microglobulin and ly-m11 by molecular cloning and DNA-mediated gene transfer.

J. Seidman, D. Margulies, J. Parnes, 1983, Proceedings of the National Academy of Sciences of the United States of America.

Chaperones and Catalysts: How Antigen Presentation Pathways Cope With Biological Necessity

D. Margulies, K. Natarajan, Jiansheng Jiang, 2022, Frontiers in Immunology.

Structures of synthetic nanobody–SARS-CoV-2 receptor-binding domain complexes reveal distinct sites of interaction

D. Margulies, Rick Huang, K. Natarajan, 2021, Journal of Biological Chemistry.

Structures of synthetic nanobody–SARS-CoV-2–RBD complexes reveal distinct sites of interaction and recognition of variants

D. Margulies, Rick Huang, K. Natarajan, 2021, Research square.

Direct detection of major histocompatibility complex class I binding to antigenic peptides using surface plasmon resonance. Peptide immobilization and characterization of binding specificity.

D. Margulies, M. Corr, J. Inman, 1993, The Journal of biological chemistry.

Structural Basis of the CD8αβ/MHC Class I Interaction: Focused Recognition Orients CD8β to a T Cell Proximal Position12

D. Margulies, K. Natarajan, Rui Wang, 2009, The Journal of Immunology.

Molecular Biology

D. Margulies, 2011 .

Molecular Biology

D. Margulies, 2010 .

Molecular Biology

D. Margulies, 2007 .

Molecular Biology

D. Margulies, 2004 .

Molecular Biology

D. Margulies, 2004 .

Molecular Biology

D. Margulies, 2002 .

Polymorphism at position nine of the MHC class I heavy chain affects the stability of association with beta 2-microglobulin and presentation of a viral peptide.

D. Margulies, R. Ribaudo, 1995, Journal of immunology.

Effects of Cross-Presentation, Antigen Processing, and Peptide Binding in HIV Evasion of T Cell Immunity

J. Berzofsky, D. Margulies, P. Berman, 2018, The Journal of Immunology.

NK and CTL recognition of a single chain H-2Dd molecule: distinct sites of H-2Dd interact with NK and TCR.

J. Berzofsky, D. Margulies, J. Dorfman, 1999, Journal of immunology.

Alternative protein products with different carboxyl termini from a single class I gene, H-2Kb.

J. Coligan, D. Margulies, J. McCluskey, 1986, Proceedings of the National Academy of Sciences of the United States of America.

Decorating bacteria with self-assembled synthetic receptors

T. Salame, D. Margulies, T. Unger, 2020, Nature Communications.

Peptide and beta 2-microglobulin regulation of cell surface MHC class I conformation and expression.

R. Germain, D. Margulies, G. Otten, 1992, Journal of immunology.

Glycoform Differentiation by a Targeted, Self-Assembled, Pattern-Generating Protein Surface Sensor.

D. Margulies, A. Rabinkov, Leila Motiei, 2020, Journal of the American Chemical Society.

Protein-Protein Communication and Enzyme Activation Mediated by a Synthetic Chemical Transducer.

D. Margulies, Leila Motiei, T. Ilani, 2015, Journal of the American Chemical Society.

on by bivalent , ‘ turn-on ’ fl uorescent molecular probes †

M. Eisenstein, D. Margulies, B. Rout, 2015 .

Analysis of a defect in the H-2 genes of SV40 transformed C3H fibroblasts that do not express H-2Kk.

G. Evans, D. Margulies, L. Gooding, 1983, Journal of immunology.

Message in a molecule

Leila Motiei, David Margulies, Tanmay Sarkar, 2016, Nature Communications.

User Authorization at the Molecular Scale.

Omer Lustgarten, Leila Motiei, David Margulies, 2017, Chemphyschem : a European journal of chemical physics and physical chemistry.

Tribological issues in perpendicular recording media

Kentaro Takano, R. J. Waltman, D. Margulies, 2007 .

Reciprocal cytotoxic T lymphocyte cross-reactivity interactions between two major epitopes within HIV-1 gp160.

J. Berzofsky, D. Margulies, K. Kurokohchi, 1996, Journal of immunology.

Crystal structure of the Ly49I natural killer cell receptor reveals variability in dimerization mode within the Ly49 family.

D. Margulies, R. Mariuzza, K. Natarajan, 2002, Journal of molecular biology.

Encrypting messages with artificial bacterial receptors

D. Margulies, Leila Motiei, Naama Lahav-Mankovski, 2020, Beilstein journal of organic chemistry.

A Molecular Secret Sharing Scheme.

Omer Lustgarten, Raanan Carmieli, Leila Motiei, 2018, Angewandte Chemie.

Combinatorial Fluorescent Molecular Sensors: The Road to Differential Sensing at the Molecular Level

Leila Motiei, D. Margulies, David Margulies, 2014, Synlett.

Cellular Expression and Crystal Structure of the Murine Cytomegalovirus Major Histocompatibility Complex Class I-like Glycoprotein, m153*

D. Margulies, H. Šimić, S. Jonjić, 2007, Journal of Biological Chemistry.

Enzyme-Artificial Enzyme Interactions as a Means for Discriminating among Structurally Similar Isozymes.

Leila Motiei, Karuthapandi Selvakumar, D. Margulies, 2015, Journal of the American Chemical Society.

Sensing Protein Surfaces with Targeted Fluorescent Receptors.

S. Albeck, D. Margulies, A. Rabinkov, 2015, Chemistry.

Mouse Cytomegalovirus m153 Protein Stabilizes Expression of the Inhibitory NKR-P1B Ligand Clr-b

D. Margulies, S. Jonjić, A. Makrigiannis, 2019, Journal of Virology.

Chaperone function in antigen presentation by MHC class I molecules—tapasin in the PLC and TAPBPR beyond

D. Margulies, K. Natarajan, Jiansheng Jiang, 2023, Frontiers in Immunology.

SARS-CoV-2 antibodies recognize 23 distinct epitopic sites on the receptor binding domain

M. Meier-Schellersheim, D. Margulies, K. Natarajan, 2023, Research square.

Structure and function of natural killer cell receptors: multiple molecular solutions to self, nonself discrimination.

D. Margulies, R. Mariuzza, K. Natarajan, 2002, Annual review of immunology.

The structure of mouse cytomegalovirus m04 protein obtained from sparse NMR data reveals a conserved fold of the m02-m06 viral immune modulator family.

A. Bax, Jinfa Ying, D. Margulies, 2014, Structure.

A Novel MHC-I Surface Targeted for Binding by the MCMV m06 Immunoevasin Revealed by Solution NMR*

A. Bax, Jinfa Ying, D. Margulies, 2015, The Journal of Biological Chemistry.

Protein recognition by a pattern-generating fluorescent molecular probe.

D. Margulies, T. Unger, H. Barr, 2017, Nature nanotechnology.

Lipopolysaccharide-Induced CD300b Receptor Binding to Toll-like Receptor 4 Alters Signaling to Drive Cytokine Responses that Enhance Septic Shock.

J. Coligan, D. Margulies, Chen-feng Qi, 2016, Immunity.

Home schooling of NK cells.

D. Margulies, 2009, Immunity.

Medication detection by a combinatorial fluorescent molecular sensor.

D. Margulies, M. Iron, B. Rout, 2012, Angewandte Chemie.

A Molecular Secret Sharing Scheme.

D. Margulies, R. Carmieli, Leila Motiei, 2018, Angewandte Chemie.

Structural Basis of the CD8αβ/MHC Class I Interaction: Focused Recognition Orients CD8β to a T Cell Proximal Position12

D. Margulies, K. Natarajan, Rui Wang, 2009, The Journal of Immunology.

Membrane Ia expression and antigen-presenting accessory cell function of L cells transfected with class II major histocompatibility complex genes

R. Germain, D. Margulies, D. M. Bentley, 1984, The Journal of experimental medicine.

Enzyme-Artificial Enzyme Interactions as a Means for Discriminating among Structurally Similar Isozymes.

D. Margulies, Leila Motiei, Karuthapandi Selvakumar, 2015, Journal of the American Chemical Society.

Antigen-processing and presentation pathways select antigenic HIV peptides in the fight against viral evolution

D. Margulies, 2009, Nature Immunology.

SARS-CoV-2 antibodies recognize 23 distinct epitopic sites on the receptor binding domain

D. Margulies, K. Natarajan, Jiansheng Jiang, 2023, Communications biology.

Degenerate MHC restriction reveals the contribution of class I MHC molecules in determining the fine specificity of CTL recognition of an immunodominant determinant of HIV-1 gp160 V3 loop.

J. Berzofsky, D. Margulies, M. Shirai, 1997, Journal of immunology.

Preface

J. Coligan, D. Margulies, E. Shevach, 2010 .

Preface

J. Coligan, D. Margulies, E. Shevach, 2005 .

Preface

J. Coligan, D. Margulies, E. Shevach, 2005 .

Protein-Protein Communication and Enzyme Activation Mediated by a Synthetic Chemical Transducer.

D. Margulies, Leila Motiei, T. Ilani, 2015, Journal of the American Chemical Society.

Monoclonal Antibodies: Producing Magic Bullets by Somatic Cell Hybridization

D. Margulies, 2005, The Journal of Immunology.

Bullets by Somatic Cell Hybridization Monoclonal Antibodies: Producing Magic

D. Margulies, 2013 .

Crystal structure of a TAPBPR–MHC I complex reveals the mechanism of peptide editing in antigen presentation

D. Margulies, K. Natarajan, Jiansheng Jiang, 2017, Science.

A structural and molecular dynamics approach to understanding the peptide-receptive transition state of MHC-I molecules.

D. Margulies, K. Natarajan, H. Robinson, 2013, Molecular immunology.