A. Kleber

发表

Basic mechanisms of cardiac impulse propagation and associated arrhythmias.

Y. Rudy, A. Kleber, 2004, Physiological reviews.

Cardiac tissue geometry as a determinant of unidirectional conduction block: assessment of microscopic excitation spread by optical mapping in patterned cell cultures and in a computer model.

V. Fast, A. Kleber, 1995, Cardiovascular research.

Genetic and Molecular Basis of Cardiac Arrhythmias: Impact on Clinical Management

R. Hauer, S. Priori, D. Roden, 2022 .

Genetic and molecular basis of cardiac arrhythmias: impact on clinical management part III.

R. Hauer, S. Priori, D. Roden, 1999, Circulation.

Role of wavefront curvature in propagation of cardiac impulse.

V. Fast, A. Kleber, Vladimir G. Fast, 1997, Cardiovascular research.

Electrical uncoupling and increase of extracellular resistance after induction of ischemia in isolated, arterially perfused rabbit papillary muscle.

A. Kleber, M. Janse, C. Riegger, 1987, Circulation research.

ST-segment elevation in the electrocardiogram: a sign of myocardial ischemia.

A. Kleber, 2000, Cardiovascular research.

Cooperative coupling of cell-matrix and cell–cell adhesions in cardiac muscle

Kevin Kit Parker, Hyungsuk Lee, Megan L. McCain, 2012, Proceedings of the National Academy of Sciences.

The “Border Zone” in Myocardial Ischemia: An Electrophysiological, Metabolic, and Histochemical Correlation in the Pig Heart

A. Kleber, D. Durrer, M. Janse, 1979, Circulation research.

Consequences of acute ischemia for the electrical and mechanical function of the ventricular myocardium. A brief review

A. Kleber, 1990, Experientia.

Pathophysiology and Prevention of Atrial Fibrillation

Michael R. Rosen, Marianne J. Legato, Peter J. Schwartz, 2001, Circulation.

Changes in conduction velocity during acute ischemia in ventricular myocardium of the isolated porcine heart.

A. Wilde, A. Kleber, R. Coronel, 1986, Circulation.

Electrophysiological basis for arrhythmias caused by acute ischemia. Role of the subendocardium.

A. Capucci, A. Kleber, R. Coronel, 1986, Journal of molecular and cellular cardiology.

Paradoxical Improvement of Impulse Conduction in Cardiac Tissue by Partial Cellular Uncoupling

V. Fast, A. Kleber, S. Rohr, 1997, Science.

Microscopic conduction in cultured strands of neonatal rat heart cells measured with voltage-sensitive dyes.

V. Fast, A. Kleber, V G Fast, 1993, Circulation research.

Block of impulse propagation at an abrupt tissue expansion: evaluation of the critical strand diameter in 2- and 3-dimensional computer models.

V. Fast, A. Kleber, V G Fast, 1995, Cardiovascular research.

Slow conduction in cardiac tissue, I: effects of a reduction of excitability versus a reduction of electrical coupling on microconduction.

A. Kleber, S. Rohr, S Rohr, 1998, Circulation research.

Mechanism and Time Course of S‐T and T‐Q Segment Changes during Acute Regional Myocardial Ischemia in the Pig Heart Determined by Extracellular and Intracellular Recordings

D Durrer, M J Janse, A. Kleber, 1978, Circulation research.

Flow of “Injury” Current and Patterns of Excitation during Early Ventricular Arrhythmias in Acute Regional Myocardial Ischemia in Isolated Porcine and Canine Hearts: Evidence for Two Different Arrhythmogenic Mechanisms

A. Kleber, D. Durrer, M. Janse, 1980, Circulation research.

Conduction of the impulse in the ischemic myocardium — implications for malignant ventricular arrhythmias

A. Kleber, A. G. Kléber, A. Kléber, 1987, Experientia.

Propagation of Electrical Activity in Ischemic and Infarcted Myocardium as the Basis of Ventricular Arrhythmias

A. Kleber, M. Janse, ANDRÉ G. KLÉBER, 1992 .

Normal and Abnormal Conduction in the Heart

V. Fast, A. Kleber, M. Janse, 2011 .

Cellular electrical uncoupling during ischemia

H. Tan, A. Kleber, M. Janse, 1998 .

Electrical coupling of cardiac myocyte cell sheets to the heart.

A. Kleber, W. Zimmermann, T. Eschenhagen, 2006, Circulation research.

Ascona Workshop on Cardiomyocyte Biology: highlights from the Sixth International Workshop.

A. Kleber, M. Schaub, 2010, Journal of cardiovascular pharmacology.

Central role for GSK3β in the pathogenesis of arrhythmogenic cardiomyopathy.

A. Kleber, D. Judge, J. Saffitz, 2016, JCI insight.

Effects of sucrose solution on the longitudinal tissue resistivity of trabecular muscle from mammalian heart

A. Kleber, 1973, Pflügers Archiv.

A. Kleber, A. Buxton, E. Anter, 2018, JACC. Clinical electrophysiology.

Founder of cardiac cellular electrophysiology: Honouring Silvio Weidmann, 7 April 1921– 11 July 2005

A. Kleber, E. Niggli, R. Weingart, 2006, The Journal of physiology.

CLASS ICAL PERSPECT IVES Founder of cardiac cellular electrophysiology: Honouring

A. Kleber, 2005 .

Ischemia and Na+/K+ Pump Function

A. Kleber, W. Cascio, 1989 .

Autocrine Regulation of Myocyte Cx43 Expression by VEGF

A. Kleber, J. Saffitz, Kathryn A. Yamada, 2002, Circulation research.

Characterizing the Molecular Pathology of Arrhythmogenic Cardiomyopathy in Patient Buccal Mucosa Cells

H. Calkins, A. Kleber, D. Judge, 2016, Circulation. Arrhythmia and electrophysiology.

Arrhythmogenic Cardiomyopathy - New Insights into Disease Mechanisms and Drug Discovery.

A. Kleber, J. Saffitz, C. Macrae, 2014, Progress in pediatric cardiology.

An Alternatively Translated Connexin 43 Isoform, GJA1-11k, Localizes to the Nucleus and Can Inhibit Cell Cycle Progression

A. Kleber, T. Hong, R. Shaw, 2020, Biomolecules.

Ventricular Arrhythmias in the First 15 Minutes of Acute Regional Myocardial Ischemia in the Isolated Pig Heart: Possible Role of Injury Currents

A. Kleber, D. Durrer, M. Janse, 1980 .

Rapid Communications Anisotropic Conduction in Monolayers of Neonatal Rat Heart Cells Cultured

V. Fast, A. Kleber, 2005 .

Activation During Sinus Rhythm in Ventricles With Healed Infarction: Differentiation Between Arrhythmogenic and Nonarrhythmogenic Scar.

A. Kleber, A. Buxton, E. Anter, 2019, Circulation. Arrhythmia and electrophysiology.

Slow conduction in cardiac tissue: insights from optical mapping at the cellular level.

A. Kleber, S. Rohr, J. Kucera, 2001, Journal of electrocardiology.

Extracellular volume and transsarcolemmal proton movement during ischemia and reperfusion: A 31P NMR spectroscopic study of the isovolumic rat heart

S. Neubauer, K. Clarke, A. Kleber, 1993, NMR in biomedicine.

No effect of thromboxane A2 on the attachment of tumor cell lines MDA MB 231, DU145, and U937 to the basement membrane in an in-vitro model.

R. Hartmann, A. Kleber, J. Jose, 2001, Journal of Cancer Research and Clinical Oncology.

Techniques and Problems in Correlating Cellular Electrophysiology and Morphology in Cardiac Nodal Tissues

A. Kleber, M. Janse, J. Tranum-Jensen, 1978 .

The Effect of the Finite Extracellular Resistance on Impulse Conduction in the Ventricular Myocardium

A. Kleber, G. Yan, 1991 .

Pathophysiology and Prevention of Atrial Fibrillation Current

M. Allessie, A. Camm, P. Schwartz, 2001 .

Pathophysiology and Prevention of Atrial Fibrillation Current Perspective

M. Allessie, A. Camm, P. Schwartz, 2001 .

Discontinuous Propagation of the Cardiac Impulse and Arrhythmogenesis

Y. Rudy, A. Kleber, 1999, Journal of cardiovascular electrophysiology.

Genetic and molecular basis of cardiac arrhythmias : Impact on clinical management

R. Hauer, S. Priori, D. Roden, 1999 .

Beating Guinea Pig Ventricular Muscle

A. Wilde, A. Kleber, 2005 .

Erratum: "Identification of a New Modulator of the Intercalated Disc in a Zebrafish Model of Arrhythmogenic Cardiomyopathy" (Science Translational Medicine (2014) 6:261 (261er6))

H. Calkins, A. Kleber, D. Judge, 2014 .

The works of Dirk Durrer (1918–1984)

T. Opthof, Michiel J. Janse, André G. Kléber, 2012, Netherlands Heart Journal.

GJA1-20k Arranges Actin to Guide Cx43 Delivery to Cardiac Intercalated Discs

A. Kleber, T. Hong, R. Shaw, 2017, Circulation research.

Changes inconduction velocity during acute ischemia inventricular myocardium oftheisolated porcine heart

A. Kleber, 1986 .

An autonomously swimming biohybrid fish designed with human cardiac biophysics

G. Lauder, A. Kleber, K. Parker, 2022, Science.

Pathogenesis of Arrhythmogenic Cardiomyopathy.

A. Kleber, J. Saffitz, A. Asimaki, 2015, The Canadian journal of cardiology.

Electrical Propagation in Synthetic Ventricular Myocyte Strands From Germline Connexin43 Knockout Mice

Jeffrey E. Saffitz, André G. Kléber, Robert Weingart, 2004, Circulation research.

Synthetic Strands of Neonatal Mouse Cardiac Myocytes: Structural and Electrophysiological Properties

J E Saffitz, A. Kleber, J. Saffitz, 2000, Circulation research.

Extracellular potassium accumulation in acute myocardial ischemia.

A. Kleber, 1984, Journal of molecular and cellular cardiology.

Extracellular K+ and H+ shifts in early ischemia: mechanisms and relation to changes in impulse propagation.

A. Kleber, M. Janse, C. Riegger, 1987, Journal of molecular and cellular cardiology.

Electrophysiological changes and ventricular arrhythmias in the early phase of regional myocardial ischemia.

M J Janse, A. Kleber, M. Janse, 1981, Circulation research.

27 – Cell-to-Cell Communication and Impulse Propagation

A. Kleber, 2018 .

Role of the intercalated disc in cardiac propagation and arrhythmogenesis

A. Kleber, J. Saffitz, 2014, Front. Physiol..

Connexin43 ablation in foetal atrial myocytes decreases electrical coupling, partner connexins, and sodium current.

Megan L. McCain, A. Kleber, K. Parker, 2012, Cardiovascular research.

The Interaction Between Na+ and Ca2+ Inward Currents in Cardiac Propagation.

A. Kleber, A. L. Wit, 2020, Circulation research.

Identification of a New Modulator of the Intercalated Disc in a Zebrafish Model of Arrhythmogenic Cardiomyopathy

H. Calkins, A. Kleber, D. Judge, 2014, Science Translational Medicine.

Dephosphorylation and Intracellular Redistribution of Ventricular Connexin43 During Electrical Uncoupling Induced by Ischemia

J E Saffitz, R B Schuessler, A. Kleber, 2000, Circulation research.

The fibrillating atrial myocardium. What can the detection of wave breaks tell us?

A. Kleber, A G Kleber, A. Kléber, 2000, Cardiovascular research.

Animal models of cardiac arrhythmias.

A. Kleber, T. Opthof, M. Janse, 1998, Cardiovascular research.

Metastable Atrial State Underlies the Primary Genetic Substrate for MYL4 Mutation-Associated Atrial Fibrillation

Michael J. Steinbaugh, S. Sui, A. Kleber, 2019, Circulation.

Relative Contributions of Connexins 40 and 43 to Atrial Impulse Propagation in Synthetic Strands of Neonatal and Fetal Murine Cardiomyocytes

A. Kleber, J. Saffitz, A. Baertschi, 2006, Circulation research.

Adenoviral Expression of IKs Contributes to Wavebreak and Fibrillatory Conduction in Neonatal Rat Ventricular Cardiomyocyte Monolayers

José Jalife, Stephan Rohr, Sandeep V Pandit, 2007, Circulation research.

Pulsatile Stretch Remodels Cell-to-Cell Communication in Cultured Myocytes

J E Saffitz, A. Kleber, J. Saffitz, 2000, Circulation research.

Functional and structural assessment of intercellular communication. Increased conduction velocity and enhanced connexin expression in dibutyryl cAMP-treated cultured cardiac myocytes.

J E Saffitz, V. Fast, A. Kleber, 1996, Circulation research.

Circulating MicroRNA-30d Is Associated With Response to Cardiac Resynchronization Therapy in Heart Failure and Regulates Cardiomyocyte Apoptosis: A Translational Pilot Study

Jagmeet P. Singh, D. Kass, Saumya Das, 2015, Circulation.

Real time, confocal imaging of Ca(2+) waves in arterially perfused rat hearts.

Lorenz Büchler, A. Baader, A. Kleber, 2002, Cardiovascular research.

The search for novel antiarrhythmic strategies

G. Breithardt, R. Campbell, A. Camm, 1998 .

Effects of mechanical forces and mediators of hypertrophy on remodeling of gap junctions in the heart.

A. Kleber, J. Saffitz, Jeffrey E Saffitz, 2004, Circulation research.

New approaches to antiarrhythmic therapy: emerging therapeutic applications of the cell biology of cardiac arrhythmias(1).

J. Camm, C. January, D. Roden, 2001, Cardiovascular research.

Gap Junctions in the Heart Effects of Mechanical Forces and Mediators of Hypertrophy on Remodeling of

A. Kleber, J. Saffitz, 2004 .

Mediators of Cardiac Hypertrophy and Failure and Mechanical Forces Regulate Gap Junctional Conductance Regulatory Sites on Connexin Proteins , Connexin

A. Kleber, J. Saffitz, 2004 .

Effect of Oxygen Withdrawal on Active and Passive Electrical Properties of Arterially: Perfused Rabbit Ventricular Muscle

A. Kleber, C. Riegger, G. Alperovich, 1989, Circulation research.

A micropatterning approach for imaging dynamic Cx43 trafficking to cell–cell borders

Luke P. Lee, A. Kleber, SoonGweon Hong, 2014, FEBS letters.

Gap junctions, slow conduction, and ventricular tachycardia after myocardial infarction.

A. Kleber, J. Saffitz, 2012, Journal of the American College of Cardiology.

Spatial changes in transmembrane potential during extracellular electrical shocks in cultured monolayers of neonatal rat ventricular myocytes.

V. Fast, A. Kleber, A. Gillis, 1996, Circulation research.

Anisotropic activation spread in heart cell monolayers assessed by high-resolution optical mapping. Role of tissue discontinuities.

V. Fast, A. Kleber, J. Saffitz, 1996, Circulation research.

Anisotropic conduction in monolayers of neonatal rat heart cells cultured on collagen substrate.

V. Fast, A. Kleber, 1994, Circulation research.

Fibrosis and Arrhythmogenesis

A. Kleber, M. Janse, 2019, Cardiac Mapping.

The shape of the electrical action-potential upstroke: a new aspect from optical measurements on the surface of the heart.

A. Kleber, André G Kléber, 2005, Circulation research.

Optical recording of impulse propagation in designer cultures. Cardiac tissue architectures inducing ultra-slow conduction.

A. Kleber, S. Rohr, S Rohr, 1999, Trends in cardiovascular medicine.

Slow conduction in cardiac tissue, II: effects of branching tissue geometry.

A. Kleber, S. Rohr, S Rohr, 1998, Circulation research.

Activation of cardiac tissue by extracellular electrical shocks: formation of 'secondary sources' at intercellular clefts in monolayers of cultured myocytes.

V. Fast, A. Kleber, A. Gillis, 1998, Circulation research.

Patterned growth of neonatal rat heart cells in culture. Morphological and electrophysiological characterization.

A. Kleber, S. Rohr, S Rohr, 1991, Circulation research.

The Role of Microscopic Tissue Structure in Defibrillation

A. Kleber, A. Gillis, 2021, Cardiac Bioelectric Therapy.

Microstructure, Cell-to-Cell Coupling, and Ion Currents as Determinants of Electrical Propagation and Arrhythmogenesis.

Stephan Rohr, A. Kleber, S. Rohr, 2017, Circulation. Arrhythmia and electrophysiology.

Substrates of Cardiac Reentrant Arrhythmias: The Possible Role of Tissue Regeneration and Replacement

A. Kleber, 2011 .

Chapter 24 – Intercellular Communication and Impulse Propagation

A. Kleber, 2004 .

Ionic Imbalance in Acute Myocardial Ischemia

A. Kleber, W. Cascio, G. Yan, 1989 .

Insights into the Pathogenesis of Catecholaminergic Polymorphic Ventricular Tachycardia from Engineered Human Heart Tissue.

Vassilios J. Bezzerides, W. Pu, A. Kleber, 2019, Circulation.

Ablation of Reentry-Vulnerable Zones Determined by Left Ventricular Activation From Multiple Directions: A Novel Approach for Ventricular Tachycardia Ablation

P. Neužil, J. Petrů, A. Kleber, 2020, Circulation. Arrhythmia and electrophysiology.

A. Kleber, M. Janse, 2003 .

Endothelial extracellular vesicles contain protective proteins and rescue ischemia-reperfusion injury in a human heart-on-chip

Johan U. Lind, Benjamin D. Pope, B. Budnik, 2020, Science Translational Medicine.

GJA1-20k, an internally translated isoform of Connexin 43, is an actin capping protein

A. Kleber, T. Hong, R. Shaw, 2022, bioRxiv.

Auxiliary trafficking subunit GJA1-20k protects Connexin43 from degradation and limits ventricular arrhythmias.

A. Kleber, P. Lampe, M. Katsumata, 2020, The Journal of clinical investigation.

The early years of cellular cardiac electrophysiology and Silvio Weidmann (1921-2005).

A. Kleber, E. Niggli, R. Weingart, 2006, Heart rhythm.

Cell‐to‐Cell Coupling Between Host and Donor Cells in the In Situ Myocardium

A. Kleber, 2003, Circulation research.

Engineering Cardiac Cell Junctions In Vitro to Study the Intercalated Disc

Megan L. McCain, A. Kleber, T. Desplantez, 2014, Cell communication & adhesion.

Gap junctions and conduction of cardiac excitation.

A. Kleber, 2011, Heart rhythm.

Coupling between cardiac cells-An important determinant of electrical impulse propagation and arrhythmogenesis.

A. Kleber, Qianru Jin, 2021, Biophysics reviews.

Cell-to-cell coupling in engineered pairs of rat ventricular cardiomyocytes: relation between Cx43 immunofluorescence and intercellular electrical conductance.

Megan L. McCain, A. Kleber, K. Parker, 2012, American journal of physiology. Heart and circulatory physiology.

Virtual sources associated with linear and curved strands of cardiac cells.

L Tung, A. Kleber, L. Tung, 2000, American journal of physiology. Heart and circulatory physiology.

Oita International Electrocardiology Symposium 2000 “Electrophysiology and Management of Lethal Arrhythmias in the New Millennium: From Genes to Bedside”

A. Kleber, S. Rohr, J. Kucera, 2000 .

Na+ channel transfection to rescue propagation.

A. Kleber, 2010, Heart rhythm.

Role of the Cardiac Sodium Current in Excitability and Conduction

A. Kleber, 2014 .

Electrical Coupling and Propagation in Engineered Ventricular Myocardium With Heterogeneous Expression of Connexin43

Megan L. McCain, A. Kleber, K. Parker, 2012, Circulation research.

Crosstalk between theoretical and experimental studies for the understanding of cardiac electrical impulse propagation.

A. Kleber, 2007, Journal of electrocardiology.

conductancece and intercellular electrical ventricular cardiomyocytes: relation between Cx43 Cell-to-cell coupling in engineered pairs of rat

Megan L. McCain, A. Kleber, K. Parker, 2012 .

Impulse Propagation in Synthetic Strands of Neonatal Cardiac Myocytes With Genetically Reduced Levels of Connexin43

Yoram Rudy, Y. Rudy, A. Kleber, 2003, Circulation research.

Abstract 15076: Altered Trafficking of Junctional Proteins Mediated by SAP97 in Arrhythmogenic Cardiomyopathy

A. Kleber, J. Saffitz, C. Macrae, 2013 .

Virtual Sources and Sinks During Extracellular Field Shocks in Cardiac Cell Cultures: Effects of Source-Sink Interactions Between Adjacent Tissue Boundaries

A. Kleber, M. Lemay, J. Kucera, 2012, Circulation. Arrhythmia and electrophysiology.

From the Needle to the Optrode:

A. Kleber, 2003 .

Molecular and cellular aspects of re-entrant arrhythmias

V. Fast, A. Kleber, A. G. Kleber, 2004, Basic Research in Cardiology.

Cardiac cell-to-cell junctions as an origin of inherited arrhythmogenic disorders.

A. Kleber, 2007, Heart rhythm.

Pathophysiology of acute ischemia: Potential targets for antiarrhythmic drugs

A. Kleber, 1994 .